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Dissertations / Theses on the topic 'Polymorphism'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Balasubramaniam, Dharini. "Extension polymorphism." Thesis, University of St Andrews, 1998. http://hdl.handle.net/10023/13495.

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Any system that models a real world application has to evolve to be consistent with its changing domain. Dealing with evolution in an effective manner is particularly important for those systems that may store large amounts of data such as databases and persistent languages. In persistent programming systems, one of the important issues in dealing with evolution is the specification of code that will continue to work in a type safe way despite changes to type definitions. Polymorphism is one mechanism which allows code to work over many types. Inclusion polymorphism is often said to be a model

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2

McLure, Craig Anthony. "Duplication and polymorphism with particular reference to regulators of complement activation." University of Western Australia. Centre for Molecular Immunology and Instrumentation, 2005. http://theses.library.uwa.edu.au/adt-WU2005.0103.

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[Truncated abstract] For the convenience of the reader, detailed figures and tables have been enlarged and compiled in Appendix 2, at the end of this thesis. This thesis is presented as an approach to identify, annotate and detect genomic duplication and polymorphism within large genomic regions. To demonstrate this, I have used as a model, the genomic region known as the Regulators of Complement Activation (RCA). The RCA complex is located on the long arm of chromosome 1 at position 1q32 and is a reservoir of complement regulatory proteins. The genes of the RCA share many similarities implyi

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3

Li, Wenjing. "Nucléation non-photochimique induite par laser (NPLIN) : Contribution au mécanisme de nucléation à travers des études expérimentales sur le sulfathiazole, L-acide glutamique et la glycine et la modélisation de quelques petites molécules." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLC019.

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Cette thèse a pour but de démontrer la faisabilité de la technique de Nucléation non-Photochimique Induite par Laser (NPLIN) appliquée aux composés pharmaceutiques organiques. Avec nos résultats expérimentaux, ceux obtenus dans la littérature et calculs théoriques ab initio, nous avons discuté du mécanisme de la méthode NPLIN.Cette thèse a décrit en premier lieu, le nouveau montage expérimental semi-automatisé adapté aux exigences des études NPLIN développé à CentraleSupelec. Des expériences NPLIN sur le sulfathiazole (STZ), l-acid glutamique (LGA) et la glycine (GLY) sont menées pour étudier

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4

Lamarche, François 1955. "Modelling polymorphism with categories." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75961.

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In this work we describe a category of domains, whose objects are in general categories instead of posets, such that J.-Y. Girard's category of qualitative domains and stable functions is contained in it as a full subcategory. We describe two ways of interpreting Martin-Lof type theory in this category, the first one allowing $ Sigma$ and $ Pi$, the second one only $ Pi$. Finally we show how to extend the second interpretation to a model of the theory of constructions.

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5

Bano, Anthony M. "Polymorphism in biomineral nanoparticles." Thesis, University of Warwick, 2012. http://wrap.warwick.ac.uk/49891/.

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Biomineralisation is the process by which living things produce hard mineral tissues with unique physical properties. The study of this process can help us produce biomimetic materials, reproducing such properties, with the study of nucleation and crystallisation of the materials being particularly important. I have used molecular simulation techniques to help gain a greater understanding of these processes, focussing particularly on identifying the conformations and solid phases available to nanoparticles of two biomineral compounds. The bones and teeth of mammals are made largely of calcium

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6

Wilkie, Susan Elizabeth. "DNA polymorphism in Allium." Thesis, University of Hertfordshire, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332242.

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7

Pidvysotska, N. I. "Polymorphism of Edwards syndrome." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/17149.

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8

Maneggia, Paola. "Models of linear polymorphism." Thesis, University of Birmingham, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414964.

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9

Saraph, A. "Nucleotide polymorphism in schizophrenia." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2002. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2774.

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10

Zhang, Shuohao. "Supporting polymorphism in XML data." Online access for everyone, 2006. http://www.dissertations.wsu.edu./Dissertations/Summer2006/s%5Fzhang%5F071906.pdf.

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11

Ogbebor, Omokhaye P. "Studies on rabies virus polymorphism." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6079.

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Rabies viruses have very simple genomes made up of single-stranded, negative sense, non-segmented ribonucleic acid (RNA). Most, if not all RNA virus populations may exist as complex mixtures of genetic and phenotypic variants often referred to as quasispecies populations. A quantitative relative fitness assay has previously been used to demonstrate loss of fitness in RNA virus populations due to Muller's Ratchet and to show gains of fitness by natural selection during virus passages. Due to their mutation rates, rapid replication, large population sizes and controlled (variable or constant) ho

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12

Hafez, Ismail Mahmoud. "Lipid polymorphism and intracellular delivery." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0021/NQ56555.pdf.

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13

Wang, Wei. "Plasminogen polymorphism in dairy cattle." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=26174.

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A genetic approach to lowering protease (plasmin) levels in milk, requires the presence of polymorphism of bovine plasminogen. This study was conducted to determine to what extent genetic polymorphism exists in dairy cattle. Bovine plasminogen was first purified from Holstein cow plasma by affinity chromatography on Lysine-Sepharose and antibodies to bovine plasminogen were raised by monthly intramuscular injection of the isolated bovine plasminogen into rabbits. For plasminogen phenotyping, blood samples were collected at random from 50 Holstein and Ayrshire cattle, and plasminogen was isolat

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14

Budd, Laura Elizabeth. "Polymorphism in small organic compounds." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/3967.

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The effect of temperature on the crystal structure of deuterated piperidine has been studied using neutron powder diffraction. Differential scanning calorimetry indicates that there are multiple phases accessible via changes in temperature however there is no evidence of this in the neutron powder diffraction study with only one phase observed in the range 2 – 250 K and under various crystallisation conditions. The effect of pressure up to 2.79 GPa has also been determined. The compression of the structure is facilitated through the closing up of voids in the structure and no phase transition

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15

Fonseca, Gutierrez Maria del Carmen. "Genetic polymorphism in systemic sclerosis." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409294.

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16

Marshall, Karen Elizabeth. "Structural polymorphism of amyloidogenic peptides." Thesis, University of Sussex, 2010. http://sro.sussex.ac.uk/id/eprint/2447/.

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The folding of a protein from a linear chain of amino acids into its functional native state is one of the most widely investigated yet enigmatic events to take place in the natural world. An ever‐increasing number of proteins and peptides are known to fold, or “misfold”, into protease‐resistant amyloid fibrils that share a common cross‐β structure, despite having no apparent sequence homology. Self‐assembly of particular proteins or peptides into amyloid is believed to be the molecular basis of many diseases, including Alzheimer's Disease, Type II diabetes and the transmissible spongiform enc

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17

Mitchell, John Edward. "Structural polymorphism in repeated DNA." Thesis, University of Portsmouth, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306945.

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18

Lundy, Zoe. "Functional consequences of MICA polymorphism." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711616.

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19

Nguyen, Thi Yen. "Polymorphism of Organic Molecular Crystals." Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/18812.

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Die Kristallisation ist ein wichtiger Teilprozess bei der industriellen Herstellung vieler Materialien und Medikamente. Es ist jedoch ein vielschichtiger, physikalischer Vorgang, der noch nicht vollständig aufgeklärt ist. Der Schwerpunkt dieser Arbeit liegt auf der Kristallisation von organischen, polymorphen Verbindungen aus unterschiedlichen Lösungsmitteln. Die Kristallisationsstudien wurden in einem akustischen Levitator mit Klimakammer, der den Einfluss von Temperatur, Feuchtigkeit und festen Oberflächen steuert, durchgeführt. Verschiedene analytische in-situ-Methoden und deren Koppl

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20

Lejeune, Julien. "Génétique et génomique des récepteurs de faible affinité pour le IgG - Implications pour le développement et l'analyse de la variabilité des effets des anticorps thérapeutiques." Thesis, Tours, 2010. http://www.theses.fr/2010TOUR3140/document.

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Les récepteurs Fc jouent un rôle important en permettant aux cellules de l’immunité d’interagir avec lesanticorps, notamment thérapeutiques. Dans cette thèse, nous montrons que des mécanismes de recombinaisonhomologue, de knock-in par insertion rétrovirale et de duplication segmentale ont permis l’acquisition chez lesPrimates (FCGR2A) puis chez les Hominidés (FCGR2C et FCGR3B) de gènes codant des récepteurs Fc ayantde nouvelles propriétés, tout en rendant instable ce cluster (variation de nombre de copies), et très complexeson analyse chez l’Homme. Grâce à une approche originale de pyroséquenc

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21

Genini, Sem. "Establishment of quick-methods to reveal DNA-polymorphisms single strand conformational polymorphism (SSCP) and heteroduplex analysis (HA) /." Zurich : Swiss Federal Institute of Technology, Department of Animal Sciences, Breeding Biology, 2002. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=50.

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22

Bilson, Richard C. "Implementing overload and polymorphism in Cforal." Waterloo, Ont. : University of Waterloo, [Dept. of Computer Science], 2003. http://etd.uwaterloo.ca/etd/rcbilson2003.pdf.

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Thesis (M.Math.)--University of Waterloo.<br>"A thesis presented to the University of Waterloo in fulfillment of the thesis requirement for the degree of Master of Mathematics in Computer Science". Includes bibliographical references.

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23

Svärd, Michael. "Crystal Polymorphism of Substituted Monocyclic Aromatics." Licentiate thesis, KTH, Chemical Engineering and Technology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-10501.

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24

Bilson, Richard C. "Implementing Overloading and Polymorphism in Cforall." Thesis, University of Waterloo, 2003. http://hdl.handle.net/10012/1166.

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The programming language Cforall extends the C language with, among other things, overloading, parametric polymorphism, and functions that can return multiple values from a single call. This thesis presents an outline of the first implementation of the core Cforall language. An effective implementation of Cforall requires complete support for new language constructs while preserving the behaviour and efficiency of existing C programs. Analyzing the meaning of Cforall programs requires significantly more sophisticated techniques than are necessary for C programs; existing techniques fo

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25

Gracin, Sandra. "Solubility and polymorphism of molecular compounds /." Stockholm, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-267.

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26

Keats, Clare J. "Crystallization and polymorphism of putative drugs." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404167.

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27

Atkinson, Kathryn. "The adaptive significance of plumage polymorphism." Thesis, University of Canterbury. Zoology, 2004. http://hdl.handle.net/10092/5813.

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Plumage polymorphism is displayed in a number of diverse species and therefore, is presumed to have evolved independently on multiple occasions. To date, no study has established whether any of the hypotheses proposed to explain its evolution in single species are relevant across all avian taxa. Using comparative analyses which included all species displaying a plumage polymorphism involving melanin pigmentation, I found no support for either sexual or apostatic selection being responsible for the evolution of plumage polymorphism. Weak support for a role for disruptive selection was indicated

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28

Koesters, Nils B. "Investigating life-history polymorphism : modelling mites." Thesis, University of Stirling, 2005. http://hdl.handle.net/1893/21630.

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The thesis presents research on the life-history polymorphism in the mite Sancassania berlesei. Males of this species are andropolymorphic: there are two distinct male phenotypes. One, the fighter, develops a third thickened leg pair, with which it kills off other fighters and males which do not exhibit a third thickened leg pair, the non-fighters. A review of the life-history of S. berlesei is given, focussing on its general biology, diet, dispersal and mating behaviour. This is followed by a review of the andropolymorphism, and the current understanding of the mechanisms underlying it. The m

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29

Lancaster, R. W. "Studies of polymorphism by physical methods." Thesis, University of East Anglia, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378885.

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30

Bartle, Elizabeth Anne. "The polymorphism of binary lipid mixtures." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305427.

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31

Hogan, J. L. "The polymorphism of headgroup methylated phosphatidylethanolamines." Thesis, University of Southampton, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235235.

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32

Lai, Tsai-Ta Christopher. "Control of polymorphism in continuous crystallization." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104203.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Continuous manufacturing has gained significant interest in recent years as the ultra-lean mode of pharmaceutical production. Albeit the increasing number of studies on the process dynamics in continuous crystallization, in particular in yield improvement and impurity separation, the research community lacks the systematic understanding of the control of polymorphism in continuous crystallization. Variations in the

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33

Boyer, Stephan. "The kernel of ad hoc polymorphism." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106072.

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Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (page 41).<br>Ad hoc polymorphism allows a value to take on multiple types, with a separate definition of the value provided for each type. We offer a new formalization of this old concept as a typed lambda calculus. Motivated by the aspiration of extending System F with ad hoc constraints, we introduce a new mechanism for implicit parameter passing. Putting these ideas together, we present a pra

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34

剛貴, 田中, and Goki Tanaka. "Structural polymorphism of alpha-synuclein fibrils." Thesis, https://doors.doshisha.ac.jp/opac/opac_link/bibid/BB13115616/?lang=0, 2019. https://doors.doshisha.ac.jp/opac/opac_link/bibid/BB13115616/?lang=0.

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35

Satarifard, Vahid. "Polymorphism of Biomembranes at the Nanoscale." Doctoral thesis, Humboldt-Universität zu Berlin, 2021. http://dx.doi.org/10.18452/22252.

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In dieser Arbeit untersuchen wir den Polymorphismus von Biomembranen im Nanometerbereich anhand von Computermodellen. In Kapitel drei werden auf Dissipative Particle Dynamis basierende molekulare Simulationen genutzt, um die Wechselwirkungen zwischen Membranen und Nanotropfen mit hohen Oberflächenspannungen in der Größenordnung von Milli Newton pro Meter zu untersuchen. Wir zeigen, dass Nanotropfen eine negative Linienspannung an der dreiphasigen Kontaktlinie mit der Membran aufweisen. Die negative Linienspannung führt zu einem spontanen Symmetriebruch des Membran-Tropfensystems und zur Bildun

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36

Mackay, Elaine A. "Polymorphism of cadmium-induced mussel metallothioneins." Thesis, University of Aberdeen, 1990. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU024434.

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Metallothioneins are ubiquitous sulphur-rich heavy metal binding proteins whose biosynthesis is induced in response to a variety of agents, including heavy metals. A number of isoforms of metallothionein are known to be induced by heavy metals in the common mussel Mytilus edulis, and recently interest has centred on the nature of these proteins and their possible utility as pollution indicator agents. Cadmium-induced metallotheioneins were isolated from mussels by procedures which included gel permeation and anion-exchange chromatography. They were shown to comprise two molecular mass classes

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37

Svärd, Michael. "Crystal polymorphism of substituted monocyclic aromatics /." Stockholm : Skolan för kemivetenskap, Kungliga Tekniska högskolan, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-10501.

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38

Hahn, Patrick Daniel. "Social control of polymorphism in Zootermopsis." Diss., The University of Arizona, 1992. http://hdl.handle.net/10150/185916.

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The sex-specific effects of reproductives and of soldiers on the reproductivity (i.e., tendency to develop into replacement reproductives) of pseudergates of Zootermopsis nevadensis were studied. Reproductives inhibit reproductivity in pseudergates of their own sex only. Reproductives neither inhibit nor stimulate reproductivity in pseudergates of the opposite sex. Reproductives do not require the presence of a reproductive of the opposite sex to stimulate them to inhibit reproductivity in pseudergates. Soldiers had no effect on the reproductivity of pseudergates. The effects of group size and

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39

Mahmoudi, Abd-elrachid. "Etude génotypique et phénotypique des polymorphismes du récepteur du complément de type 1 (CR1,CD35) dans la maladie d’Alzheimer." Thesis, Reims, 2015. http://www.theses.fr/2015REIMM201/document.

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Les études d'association pangénomiques ont permis d'identifier de nouveaux loci, dont le gène CR1 comme associé au risque de maladie d'Alzheimer (MA). Le récepteur du complément de type 1 (CR1) est une glycoprotéine transmembranaire, présente notamment à la surface des érythrocytes (CR1E), mais également dans le plasma sous forme soluble (CR1s). Le CR1 peut prendre des formes fonctionnelles différentes, qui pourraient conférer des niveaux de risque différents, voire suggérer des mécanismes physiopathologiques de la MA. Si la relation entre CR1 et MA est aujourd'hui connue, son mécanisme reste

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40

Afridi, Sarwat. "Influence de variants génétiques candidats sur des phenotypes liés au paludisme à Plasmodium falciparum et effet fonctionnel du polymorphisme NCR3-412 associés au paludisme." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM4037.

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Le paludisme est une cause majeure de morbidité et de mortalité, plus particulièrement en Afrique sub-saharienne. De très nombreuses observations sont en faveur de l'existence de facteurs génétiques contrôlant le devenir de l'infection palustre. Il est très probable que certains variants génétiques de gènes candidats du paludisme affectent la résistance du paludisme à travers leur effet sur la réponse immunitaire acquise. Afin de vérifier cette hypothèse, nous avons étudié, dans une population vivant au Burkina Faso, des variants génétiques de HBB, IL4, IL12B, TNF, LTA, FCGR2A et NCR3 dont l'a

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41

Liu, Shuk Ming. "Single nucleotide polymorphism in human microsomal glutathione s-transferase gene and colorectal cancer /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202003%20LIU.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 95-105). Also available in electronic version. Access restricted to campus users.

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42

Takeuchi, Izumi. "Theories of Parametric Polymorphism and Data Types." 京都大学 (Kyoto University), 2000. http://hdl.handle.net/2433/180905.

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43

Kabbage, Mehdi. "Amplified fragment length polymorphism in Mycosphaerella graminicola." Diss., Manhattan, Kan. : Kansas State University, 2007. http://hdl.handle.net/2097/255.

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44

Jobs, Magnus. "Technology development for genome and polymorphism analysis /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-413-5/.

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45

Jordan, Gabriele. "Polymorphism of normal colour vision in humans." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240178.

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46

Taylor, P. "Recursive domains, indexed category theory and polymorphism." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384532.

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47

Anwar, Ghazanfar Ali. "Genetic polymorphism in proinflammatory cytokines in bronchiectasis." Thesis, University of Newcastle Upon Tyne, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.576646.

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Bronchiectasis is a disease characterised by chronic bronchial sepsis and exerts considerable morbidity in those affected. In approximately 50% of cases the aetiology is unknown (idiopathic), raising the possibility of genetic predisposition. Cytokines such as IL-1, IL-6, IL-8 and TNFα are potent neutrophil recruiting molecules and are abundant in bronchiectatic secretions. Cytokine polymorph isms can lead to constitutively high production, and have been associated with a number of chronic inflammatory states. Hypothesis: Gene polymorph isms associated with high cytokine production predispose

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48

Atan, Deniz. "Cytokine gene polymorphism in non-infectious uveitis." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492470.

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Non-infectious uveitis is a blinding intraocular inflammatory disorder with an autoimmune pathogenesis. Like other autoimmune diseases, uveitis has multifactorial and polygenic aetiology. The results of this study have shown that polymorphisms of the ILIO and TNF genes influence the susceptibility and seventy of uveitis. These polymorphisms were either known to correlate with altered transcription levels, or linked with other polymorphisms positioned within regulatory conserved non-coding sequences. Thus the identification of specific genetic variants that confer susceptibility or resistance t

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49

Smith, Judith Alexis. "Polymorphism, parasites and fitness in Soay sheep." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270757.

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50

Semple, Colin A. M. "Maintenance of inversion polymorphism in Drosophila melanogaster." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/11380.

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The work which is presented investigated the maintenance of inversion polymorphism in both real and simulated populations. Observations were made of a naturally occurring polymorphism for the common cosmopolitan inversion <I>In(3R)P</I> in populations of the fruit fly <I>Drosophila melanogaster</I>. Male mating success and larval to adult viability were estimated in both inbred and outbred populations of Californian flies. In addition, departures from random mating were sought. Computer simulation of the maintenance of inversion polymorphism was also undertaken. The modelling examined the deve

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