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Journal articles on the topic 'Polysaccharide'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Al-Wraikat, Majida, Yun Liu, Limei Wu, Zeshan Ali, and Jianke Li. "Structural Characterization of Degraded Lycium barbarum L. Leaves’ Polysaccharide Using Ascorbic Acid and Hydrogen Peroxide." Polymers 14, no. 7 (2022): 1404. http://dx.doi.org/10.3390/polym14071404.

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Plant-derived polysaccharide’s conformation and chain structure play a key role in their various biological activities. Lycium barbarum L. leaves’ polysaccharide is well renowned for its health functions. However, its functional bioactivities are greatly hindered by its compact globular structure and high molecular weight. To overcome such issue and to improve the functional bioactivities of the polysaccharides, degradation is usually used to modify the polysaccharides conformation. In this study, the ethanol extract containing crude Lycium barbarum L. leaves’ polysaccharide was first extracte

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Khalilova, Gulnoza Abduvahobovna, Abbaskhan Sabirkhanovich Turaev, Bakhtiyor Ikromovich Muhitdinov, Al'bina Vasil'yevna Filatova, Saida Bokizhonovna Haytmetova, and Nodirali Sokhobatalievich Normakhamatov. "ISOLATION, PHYSICO-CHEMICAL CHARACTERISTICS OF POLYSACCHARIDE ISOLATED FROM THE FRUIT BODY OF INONOTUS HISPIDUS." chemistry of plant raw material, no. 3 (September 27, 2021): 99–106. http://dx.doi.org/10.14258/jcprm.2021039028.

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The article is devoted to the study of polysaccharides isolated from the basidiomycete raw material I. hispidus and studying their physical and chemical properties. Water-soluble polysaccharides were isolated from mushroom raw materials by the method of sequential water extraction and the yield was 9.44%. Polysaccharides were separated into neutral fractions by ion exchange chromatography and purified from proteins and peptides. During the separation process, it was determined that the polysaccharide sample consisted of homogeneous polysaccharides, while the carbohydrate content of the purifie

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3

Whang, Yoon Hee, Soo Kyung Kim, Hyeseon Yoon, et al. "Reduction of free polysaccharide contamination in the production of a 15-valent pneumococcal conjugate vaccine." PLOS ONE 15, no. 12 (2020): e0243909. http://dx.doi.org/10.1371/journal.pone.0243909.

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Glycoconjugate vaccines are vaccines in which a bacterial polysaccharide antigen is conjugated to a carrier protein to enhance immunogenicity by promoting T cell-dependent immune response. However, the free (unreacted) polysaccharides remaining after the conjugation process can inhibit the immunogenicity of a conjugate vaccine. Thus, we aimed to reduce the unbound free polysaccharides in the polysaccharide-protein conjugation process for the development of a new 15-valent pneumococcal conjugate vaccine (PCV15) by varying some factors that may affect the conjugation results such as polysacchari

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4

Chen, Yan, Hanchen Du, Wenjie Qu, et al. "Comparison of Polygonatum sibiricum Polysaccharides from Different Extraction Methods." Foods 14, no. 13 (2025): 2188. https://doi.org/10.3390/foods14132188.

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Although our previous research has indicated that the ultrasound-assisted extraction–deep eutectic solvent method possessed the highest extraction yield for Polygonatum sibiricum Polysaccharide, it is uncertain whether the Polygonatum sibiricum Polysaccharide that was extracted by the ultrasound-assisted extraction–deep eutectic solvent method possesses the same performance as that extracted by other methods and whether separation and purification affect the performance of Polygonatum sibiricum Polysaccharide. This paper aimed to compare the differences in performance among the Polygonatum sib

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5

Schifferle, R. E., H. J. Jennings, M. R. Wessels, E. Katzenellenbogen, R. Roy, and D. L. Kasper. "Immunochemical analysis of the types Ia and Ib group B streptococcal polysaccharides." Journal of Immunology 135, no. 6 (1985): 4164–70. http://dx.doi.org/10.4049/jimmunol.135.6.4164.

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Abstract The types Ia and Ib group B streptococcal type-specific polysaccharides have remarkable immunologic differences despite a great deal of structural similarity. Although these two complex polysaccharides differ only by a single glycosidic linkage, they are antigenically distinct. Furthermore, terminal sialic acid residues appear to be critical to the immunodeterminant on the type Ia polysaccharide, whereas the antigenicity of the type Ib polysaccharide does not show this dependence on sialic acid. In the current investigation we defined better the immunodeterminant of these polysacchari

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6

Guo, Qingbin, Xingyue Xiao, Laifeng Lu, et al. "Polyphenol–Polysaccharide Complex: Preparation, Characterization, and Potential Utilization in Food and Health." Annual Review of Food Science and Technology 13, no. 1 (2022): 59–87. http://dx.doi.org/10.1146/annurev-food-052720-010354.

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Polysaccharides and polyphenols coexist in many plant-based food products. Polyphenol–polysaccharide interactions may affect the physicochemical, functional, and physiological properties, such as digestibility, bioavailability, and stability, of plant-based foods. In this review, the interactions (physically or covalently linked) between the selected polysaccharides and polyphenols are summarized. The preparation and structural characterization of the polyphenol–polysaccharide conjugates, their structural–interaction relationships, and the effects of the interactions on functional and physiolo

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7

Yang, Haiyan, Dawei Wang, Jia Deng, et al. "Activity and Structural Characteristics of Peach Gum Exudates." International Journal of Polymer Science 2018 (June 3, 2018): 1–5. http://dx.doi.org/10.1155/2018/4593735.

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Polysaccharide fractions were prepared from peach gum exudates by treatments with alkaline hydrogen peroxide (AHP) and liquid hot water (LHW). The structural characteristics and activities of the polysaccharide fractions were comparatively studied. The results suggested that arabinogalactans substituted with xylose and uronic acids were the main structure of all polysaccharide fractions. AHP and LHW treatments introduced the degradation of the polysaccharides, reducing the molecular weight of polysaccharides from 182500 g/mol to 78450 g/mol and 68420 g/mol, respectively. The decreasement of mo

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8

Savidge, Rodney Arthur, and J. Ross Colvin. "Production of cellulose and soluble polysaccharides by Acetobacter xylinum." Canadian Journal of Microbiology 31, no. 11 (1985): 1019–25. http://dx.doi.org/10.1139/m85-192.

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Alkali-insoluble cellulose and water-soluble polysaccharide production by wild-type Acetobacter xylinum colony and liquid cultures was investigated. The mass of cellulose exceeded that of soluble polysaccharides in liquid cultures while the reverse situation occurred in colony cultures. The soluble polysaccharide fraction, 3 × 105 to 5 × 105 in molecular weight, was found by DEAE-Sephacel chromatography to be a complex of several acidic, nitrogenfree polysaccharides. One acidic polysaccharide was predominant in the complex, and gas–liquid chromatography and mass spectrometry showed this to con

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9

Wang, Zi, Ju-Hong Chen, Ling-Shuai Wang, Juan Ding, Ming-Wen Zhao, and Rui Liu. "GlPP2C1 Silencing Increases the Content of Ganodermalingzhi Polysaccharide (GL-PS) and Enhances Slt2 Phosphorylation." Journal of Fungi 8, no. 9 (2022): 949. http://dx.doi.org/10.3390/jof8090949.

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Polysaccharides have attracted much attention in the food industry due to their diverse biological activities. To date, research on the mechanism of polysaccharide synthesis has mainly focused on the role of crucial enzymes in the polysaccharide synthesis pathway, but other genes that regulate polysaccharide synthesis have not been well explored. In this study, the GlPP2C1 gene, encoding a phosphoprotein type 2C phosphatase, was cloned, and PP2C-silenced strains (PP2C1i-1 and PP2C1i-3) were screened. Measurements of the polysaccharide content and cell wall tolerance revealed that GlPP2C1 silen

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10

Wang, Qiong, Mengmeng Xu, Liting Zhao, Lei Chen, and Zhongyang Ding. "Novel Insights into the Mechanism Underlying High Polysaccharide Yield in Submerged Culture of Ganoderma lucidum Revealed by Transcriptome and Proteome Analyses." Microorganisms 11, no. 3 (2023): 772. http://dx.doi.org/10.3390/microorganisms11030772.

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Polysaccharides are crucial dietary supplements and traditional pharmacological components of Ganoderma lucidum; however, the mechanisms responsible for high polysaccharide yields in G. lucidum remain unclear. Therefore, we investigated the mechanisms underlying the high yield of polysaccharides in submerged cultures of G. lucidum using transcriptomic and proteomic analyses. Several glycoside hydrolase (GH) genes and proteins, which are associated with the degradation of fungal cell walls, were significantly upregulated under high polysaccharide yield conditions. They mainly belonged to the GH

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11

Phomkaivon, Naraporn, Preeyanut Pongponpai, Prapat Kosawatpat, Bussaba Thongdang, and Wanida Pan-utai. "Extraction, Characterisation and Evaluation of Antioxidant and Probiotic Growth Potential of Water-Soluble Polysaccharides from Ulva rigida Macroalgae." Foods 13, no. 11 (2024): 1630. http://dx.doi.org/10.3390/foods13111630.

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Ulva rigida green macroalgae contain a variety of polysaccharides. A recent study investigated the optimum concentration and yield of polysaccharide extraction from oven-dried U. rigida biomass using a water-soluble polysaccharide extraction method that adhered to safety standards. This study utilised complete factorial experiments to examine the effects of varying factors on polysaccharide extraction. Results showed a positive correlation between increased levels of all factors and higher polysaccharide extraction yield. This study also found that the main factors and their interaction had a

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Masselot--Joubert, Loreleï, and María Agostina Di Renzo. "ATP-Binding Cassette (ABC) Transporters and Antibiotic Resistance: Specialized Systems for Capsular Polysaccharide Export in Gram-Negative Pathogens." Polysaccharides 6, no. 2 (2025): 38. https://doi.org/10.3390/polysaccharides6020038.

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ABC transporters are a large family of proteins that mediate the export or import of a variety of molecules, including capsular polysaccharides. The capsules are an important virulence factor that protect bacteria from host immune system attacks, antibiotics, and physicochemical changes in their environment. In some Gram-negative pathogenic bacteria, ABC transporter-dependent systems facilitate the export of capsular polysaccharides. These transport systems are composed of three parts: the ABC transporter and the polysaccharide co-polymerase protein in the inner membrane and the outer membrane

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13

Li, Jingyuan, Hong Xiang, Qian Zhang, and Xiaoqing Miao. "Polysaccharide-Based Transdermal Drug Delivery." Pharmaceuticals 15, no. 5 (2022): 602. http://dx.doi.org/10.3390/ph15050602.

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Materials derived from natural plants and animals have great potential for transdermal drug delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources. Compared with synthetic polymers, polysaccharides have the advantages of non-toxicity and biodegradability, ease of modification, biocompatibility, targeting, and antibacterial properties. Currently, polysaccharide-based transdermal drug delivery vehicles, such as hydrogel, film, microneedle (MN), and tissue scaffolds are being developed. The addition of polysaccharides allows these vehicles to exhibit better-swelli

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14

Yong, Raymond N., and Diana Mourato. "Influence of polysaccharides on kaolinite structure and properties in la kaolinite–water system." Canadian Geotechnical Journal 27, no. 6 (1990): 774–88. http://dx.doi.org/10.1139/t90-091.

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The influence of soil organics on the development of soil structure and behaviour of soils is the motivation for this study. Xanthan and dextran, two soil polysaccharides, were examined in relation to their influence on the development of the structure of kaolinite–polysaccharide systems and also on resultant physicochemical properties. The kaolinite–polysaccharide soils were formed in suspensions under anaerobic and low redox potential conditions to simulate environmental conditions that exist in subsurface soils. Information on the rheology of the kaolinite–polysaccharide system, zeta potent

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15

Oshchepkova, Yuliya Igorevna, and Shavkat Ismailovich Salikhov. "ISOLATION AND STUDY OF POLYSACCHARIDES OF MARGILAN RADISH RAPHANUS SATIVUS." chemistry of plant raw material, no. 3 (October 2, 2023): 109–15. http://dx.doi.org/10.14258/jcprm.20230311689.

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The purpose of this research is to isolate and study the physicochemical characteristics of polysaccharides in the seeds of the Margilan radish of the Brassicaceae family cultivated in the Republic of Uzbekistan. For the first time, a water-soluble fraction of polysaccharides was isolated from radish seeds by sowing Margilan successive extraction after the extraction of proteins and polyphenols. Anion exchange chromatography and gel filtration were used to obtain homogeneous polysaccharides. The polysaccharide fraction was separated by ion-exchange chromatography, purified on a Sephadex

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16

Vu Thi, Bach Phuong, Minh Dai Cao та Ngo Diem Phuong Quach. "Extraction and evaluation of α-glucosidase inhibitory activity of polysaccharide from Urena lobata L. roots". Research Journal of Biotechnology 18, № 8 (2023): 11–15. http://dx.doi.org/10.25303/1808rjbt011015.

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Polysaccharides are compounds found in the roots of Urena lobata L. Polysaccharides are of interest due to many valuable biological activities such as immunomodulatory, anti-cancer, diabetes treatment, anti-inflammatory and antioxidant. In this research, polysaccharides extracted from Urena lobata L. roots were analyzed by GC-MS (Gas Chromatography Mass Spectometry) and GPC (Gel Permeation Chromatography). The results show that the polysaccharide from Urena lobata L. natural roots is a heteropolysaccharide. This polysaccharide has two peaks with the weighted average molecular weights (Mw) as 1

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17

Lu, Aijing, and Suming Li. "Polysaccharides as a Hydrophilic Building Block of Amphiphilic Block Copolymers for the Conception of Nanocarriers." Pharmaceutics 16, no. 4 (2024): 467. http://dx.doi.org/10.3390/pharmaceutics16040467.

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Polysaccharides are gaining increasing attention for their relevance in the production of sustainable materials. In the domain of biomaterials, polysaccharides play an important role as hydrophilic components in the design of amphiphilic block copolymers for the development of drug delivery systems, in particular nanocarriers due to their outstanding biocompatibility, biodegradability, and structural versatility. The presence of a reducing end in polysaccharide chains allows for the synthesis of polysaccharide-based block copolymers. Compared with polysaccharide-based graft copolymers, the str

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18

Ofoedu, Chigozie E., Lijun You, Chijioke M. Osuji, et al. "Hydrogen Peroxide Effects on Natural-Sourced Polysacchrides: Free Radical Formation/Production, Degradation Process, and Reaction Mechanism—A Critical Synopsis." Foods 10, no. 4 (2021): 699. http://dx.doi.org/10.3390/foods10040699.

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Numerous reactive oxygen species (ROS) entities exist, and hydrogen peroxide (H2O2) is very key among them as it is well known to possess a stable but poor reactivity capable of generating free radicals. Considered among reactive atoms, molecules, and compounds with electron-rich sites, free radicals emerging from metabolic reactions during cellular respirations can induce oxidative stress and cause cellular structure damage, resulting in diverse life-threatening diseases when produced in excess. Therefore, an antioxidant is needed to curb the overproduction of free radicals especially in biol

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19

Zhao, Yue, Bocheng Yan, Zhaoyu Wang, Mingjing Li, and Wei Zhao. "Natural Polysaccharides with Immunomodulatory Activities." Mini-Reviews in Medicinal Chemistry 20, no. 2 (2020): 96–106. http://dx.doi.org/10.2174/1389557519666190913151632.

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Natural polysaccharide is a kind of natural macromolecular which can be extracted from plants, fungi, algae, animals, and bacteria. The monosaccharide compositions and glucosidic bonds of polysaccharides from different origins vary substantially. Natural polysaccharides have been shown to possess complex, important and multifaceted biological activities including antitumor, anticoagulant, antioxidative, antiviral, immunomodulatory, antihyperlipidemic and antihepatotoxic activities. Their properties are mainly due to their structural characteristics. It is necessary to develop polysaccharide im

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20

Pérez-Burgos, María, and Lotte Søgaard-Andersen. "Biosynthesis and function of cell-surface polysaccharides in the social bacterium Myxococcus xanthus." Biological Chemistry 401, no. 12 (2020): 1375–87. http://dx.doi.org/10.1515/hsz-2020-0217.

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AbstractIn bacteria, cell-surface polysaccharides fulfill important physiological functions, including interactions with the environment and other cells as well as protection from diverse stresses. The Gram-negative delta-proteobacterium Myxococcus xanthus is a model to study social behaviors in bacteria. M. xanthus synthesizes four cell-surface polysaccharides, i.e., exopolysaccharide (EPS), biosurfactant polysaccharide (BPS), spore coat polysaccharide, and O-antigen. Here, we describe recent progress in elucidating the three Wzx/Wzy-dependent pathways for EPS, BPS and spore coat polysacchari

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Zhang, Jing, Qian Li, Xiaochen Jiang, et al. "Effect of sulfated polysaccharides on the digestion of DNA by pepsin under simulated gastric juice in vitro." Food & Function 11, no. 2 (2020): 1790–97. http://dx.doi.org/10.1039/c9fo02578b.

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22

Han, Cheng-Feng, Shu-Ting Liu, Rong-Rong Yan, et al. "Salicylic Acid and Jasmonic Acid Increase the Polysaccharide Production of Nostoc flagelliforme via the Regulation of the Intracellular NO Level." Foods 12, no. 5 (2023): 915. http://dx.doi.org/10.3390/foods12050915.

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To significantly improve the polysaccharide production of Nostoc flagelliforme, a total of 12 chemicals were evaluated for their effects on polysaccharide accumulation. The results showed that salicylic acid and jasmonic acid increased the accumulation of the polysaccharides in N. flagelliforme significantly, by more than 20%. Three polysaccharides, namely control-capsule polysaccharide, salicylic acid-capsule polysaccharide, and jasmonic acid-capsule polysaccharide, were extracted and purified from N. flagelliforme under normal, salicylic acid, and jasmonic acid culture conditions, respective

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23

Yan, Pei Sheng, Li Ya Ma, and Li Xin Cao. "Optimization of Enzymatic Hydrolytic Extraction Conditions for High Yield Polysaccharide Manufacturing from Liquid Fermented Materials of Hypsizigus Marmoreus." Applied Mechanics and Materials 145 (December 2011): 154–58. http://dx.doi.org/10.4028/www.scientific.net/amm.145.154.

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Polysaccharides extracted from fruiting body and mycelia of higher fungi have been found to show various biological activities. Traditionally, these polysaccharides are manufactured by the hot water extraction method. Low polysaccharide yield is the disadvantage of this method. This paper reports the optimal conditions to manufacture polysaccharide with high-yield from Hypsizigus marmoreus mycelia using enzymatic hydrolytic extraction method. Neutral protease was selected as the most cost efficient among six enzymes. The uniform design was further conducted to optimize the enzymatic hydrolytic

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Dong, Shiyi, Yu Wu, Yutong Luo, et al. "Study on the Extraction Technology and Antioxidant Capacity of Rhodymenia intricata Polysaccharides." Foods 13, no. 23 (2024): 3964. https://doi.org/10.3390/foods13233964.

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A red alga named Rhodymenia intricata was explored, and the extraction technology and antioxidant capacity of its polysaccharides were investigated. The crude polysaccharides were extracted using the ultrasound-assisted water extraction method, precipitated by alcohol, and purified using the trichloroacetic acid method. Subsequently, the scavenging rates of polysaccharides on hydroxyl, DPPH, and ABTS free radicals, were determined both prior to and following purification to evaluate their antioxidant activity. Extraction technology was optimized to improve polysaccharide yield, and the optimal

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Wessels, Michael R., Lawrence C. Paoletti, Hilde-Kari Guttormsen, Francis Michon, Anello J. D’Ambra, and Dennis L. Kasper. "Structural Properties of Group B Streptococcal Type III Polysaccharide Conjugate Vaccines That Influence Immunogenicity and Efficacy." Infection and Immunity 66, no. 5 (1998): 2186–92. http://dx.doi.org/10.1128/iai.66.5.2186-2192.1998.

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ABSTRACT In this study, we tested the hypothesis that the immunogenicity and protective efficacy of polysaccharide-protein conjugate vaccines are influenced by three variables: (i) molecular size of the conjugate, (ii) molecular size of the polysaccharide used for conjugation, and (iii) extent of polysaccharide-to-protein cross-linking. Type III group B Streptococcus capsular polysaccharide was linked by reductive amination at multiple sites to tetanus toxoid to create a polysaccharide-protein conjugate (III-TT). A single lot of III-TT was fractionated into small, medium, and large M rpools. W

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Toshtemirova, Charos Toshtemirovna, Abdulhamid Abdulvohid ugli Turaboev, Nodirali Sokhobatalievich Normakhamatov, and Fotimahon Akbarovna Kodiralieva. "ISOLATION AND STUDY OF THE PHYSICOCHEMICAL PROPERTIES OF POLYSACCHARIDES FROM PLANT MATERIALS GENTIANA OLIVIERI GRISEB." chemistry of plant raw material, no. 2 (June 26, 2023): 87–95. http://dx.doi.org/10.14258/jcprm.20230211777.

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Methods for isolating and purifying polysaccharides of the aerial part from plant materials of the Gentian Olivier – Gentiana. Olivieri Griseb (family Gentianaceae ) have been developed and studied for the qualitative and quantitative content of polysaccharides in the herb as biologically active components that determine its anti-inflammatory and sequestering (moisture retention agents) effects in the normalization of gastrointestinal disorders. The qualitative and quantitative characteristics of the content of the polysaccharide complex were determined, including water-soluble polysaccharides

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Curiel-Fernández, María, Belén Ayestarán, Zenaida Guadalupe, and Silvia Pérez-Magariño. "Polysaccharide content of extracts obtained from unfermented skins from red varieties." BIO Web of Conferences 68 (2023): 02028. http://dx.doi.org/10.1051/bioconf/20236802028.

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Grape pomace is one of the main by-products generated by wine industry and contains several bioactive compounds such as polysaccharides. They are contained in the cell walls of the grape skins. The variety can be an important factor influencing the polysaccharide content of grapes. Actually, there is great interest in the revaluation of by-products and their incorporation into the production process. Therefore, the aim of this work was to evaluate the polysaccharide content of different extracts obtained from unfermented pomaces of different red grape varieties from Castilla y León. Eight diff

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Dubashynskaya, Natallia, Daria Poshina, Sergei Raik, Arto Urtti, and Yury A. Skorik. "Polysaccharides in Ocular Drug Delivery." Pharmaceutics 12, no. 1 (2019): 22. http://dx.doi.org/10.3390/pharmaceutics12010022.

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Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as polysaccharide derivatives, have been successfully used to augment drug delivery in the treatment of ocular pathologies. The properties of polysaccharides can be extensively modified to optimize ocular drug formulations and to obtain biocompatible and biodegradable drugs with improved bioavailability and tailored pharmacological effects. This review discusses the available polysaccharide choices for overcoming the difficulties associated with ocular drug delivery, and it explores the reasons for the dep

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Rohrer, Jeffrey S. "Vaccine Quality Ensured by High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection." SLAS TECHNOLOGY: Translating Life Sciences Innovation 25, no. 4 (2019): 320–28. http://dx.doi.org/10.1177/2472630319890309.

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Many important vaccines use bacterial capsular polysaccharides, or shorter polysaccharides or oligosaccharides, derived from the capsular polysaccharides, conjugated to protein. It is imperative that manufacturers understand the carbohydrate composition of these vaccines and deliver a product with a consistent polysaccharide or polysaccharide conjugate composition and content. High-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) is a major technique used to understand the carbohydrate composition of these vaccines and ensure product quality. HPAE-PAD sep

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Morais, Victor, and Norma Suarez. "Conjugation Mechanism for Pneumococcal Glycoconjugate Vaccines: Classic and Emerging Methods." Bioengineering 9, no. 12 (2022): 774. http://dx.doi.org/10.3390/bioengineering9120774.

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Licensed glycoconjugate vaccines are generally prepared using native or sized polysaccharides coupled to a carrier protein through random linkages along the polysaccharide chain. These polysaccharides must be chemically modified before covalent linking to a carrier protein in order to obtain a more defined polysaccharide structure that leads to a more rational design and safer vaccines. There are classic and new methods for site-selective glycopolysaccharide conjugation, either chemical or enzymatic modification of the polysaccharide length or of specific amino acid residues of the protein car

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Loganina, V. I., I. A. Pronin, A. A. Karmanov, and M. I. Filinova. "RHEOLOGICAL PROPERTIES OF LIME COMPOSITIONS WITH POLYSACCHARIDES ADDITIVES." Bulletin of South Ural State University series "Construction Engineering and Architecture" 24, no. 1 (2024): 28–33. http://dx.doi.org/10.14529/build240104.

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Lime compositions with polysaccharide additives are being studied. The results are aimed at creating a new lime plaster composition with improved performance properties. Materials and methods. Standard methods for studying rheological and technological properties were used. Results. The influence of polysaccharides on changes in the rheological properties of lime compositions has been established. It has been established that the introduction of a polysaccharide additive (hydroxyethylcellulose) helps to accelerate the development of plastic strength. The results of infrared spectroscopy indica

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Zhang, Jie, Kanwal Rida, Jiahao Wen, et al. "Screening of Lentinula edodes Strains for High Polysaccharide Production and In Vitro Antioxidant Activities." Journal of Fungi 11, no. 5 (2025): 347. https://doi.org/10.3390/jof11050347.

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Lentinan is one of the main metabolites of Lentinula edodes and exhibits numerous biological properties, such as antitumor and antioxidant activity. Despite recent advancements, its commercialization remains constrained by a lengthy cultivation cycle, low yield, and high cost. Therefore, screening strains with high polysaccharide production or enhanced bioactivity at the mycelial fermentation stage is of significant importance. In this study, the mycelial polysaccharide content and in vitro antioxidant activity of 18 L. edodes strains were evaluated under shaking and static culture conditions.

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Olech, Marta, Natalia Nowacka-Jechalke, Maciej Masłyk, et al. "Polysaccharide-Rich Fractions from Rosa rugosa Thunb.—Composition and Chemopreventive Potential." Molecules 24, no. 7 (2019): 1354. http://dx.doi.org/10.3390/molecules24071354.

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The huge health-beneficial potential of polysaccharides encourages the search for novel sources and applications of these compounds. One poorly explored source of polysaccharides is the rose. The content and biological activity of polysaccharides in rose organs is an almost completely unaddressed topic, therefore, polysaccharide-rich extracts (crude polysaccharides, CPLs) from petals, leaves, hips, and achenes of Rosa rugosa Thunb. were studied for their composition and the influence on various cellular processes involved in the development of cancer and other civilization diseases. The study

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Xu, Junpeng, and Shan-hui Hsu. "Enhancement of Cell Behavior by the Polysaccharide Extract of Arthrospira and Potential Biomedical Applications." Molecules 28, no. 2 (2023): 732. http://dx.doi.org/10.3390/molecules28020732.

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Arthrospira is one of the most studied cyanobacteria and has been reported with practical applications. Among the substances derived from Arthrospira, polysaccharides have received relatively less attention than phycocyanins, though they have more abundant structural variations and specific properties. Herein, a new Arthrospira-derived sulfated polysaccharide was explored for its potential bioactive functions. The ability of this sulfated polysaccharide to promote the behavior of neural stem cells (NSCs) in three-dimensional hydrogel was examined for the first time. NSCs encapsulated in the su

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Domenico, Philip, Dana L. Diedrich, and David C. Straus. "Extracellular polysaccharide production by Klebsiella pneumoniae and its relationship to virulence." Canadian Journal of Microbiology 31, no. 5 (1985): 472–78. http://dx.doi.org/10.1139/m85-088.

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Klebsiella pneumoniae serotype 1 and serotype 2 and their capsular variants were examined for production of cell-associated capsular polysaccharides and extracellular capsular polysaccharides. The virulence of these organisms in experimental animals was examined via intraperitoneal injection in mice and transtracheal inoculation into the lungs of rats. It was found that the production of either polysaccharide component correlated with the observed virulence. The extracellular polysaccharides were purified by ethanol precipitation, electrodialysis, extraction with quaternary ammonium salts, and

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Liu, Qing, Jun Tang, Siqin Li, Jing Li, Bin Tan, and Tianwei Liu. "Studies on the Extraction of Guarana Peel Polysaccharides and its Effect on Blood Glucose Lipids in Mice." Cardiovascular Reviews 2, no. 3 (2024): 7–15. http://dx.doi.org/10.26689/cr.v2i3.8354.

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Objective: To study the extraction of Guarana peel polysaccharides (GPP) by two different methods and to investigate the effect of extracted polysaccharides on haemoglycaemia and lipids in mice. Methods: The polysaccharides were extracted by aqueous alcoholic precipitation with two different solvents, methanol/ethanol mixed solvent or 95% ethanol and the mice were fed and tested for changes in endogenous related substances, respectively. Results: The concentration of polysaccharide extracted by methanol/ethanol mixed solvent was 116.367 μg/mL, while the concentration of polysaccharide extracte

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Su, Chunyu, Yutong Chen, Shujing Tian, Chunxiu Lu, and Qizhuang Lv. "Research Progress on Emerging Polysaccharide Materials Applied in Tissue Engineering." Polymers 14, no. 16 (2022): 3268. http://dx.doi.org/10.3390/polym14163268.

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The development and application of polysaccharide materials are popular areas of research. Emerging polysaccharide materials have been widely used in tissue engineering fields such as in skin trauma, bone defects, cartilage repair and arthritis due to their stability, good biocompatibility and reproducibility. This paper reviewed the recent progress of the application of polysaccharide materials in tissue engineering. Firstly, we introduced polysaccharide materials and their derivatives and summarized the physicochemical properties of polysaccharide materials and their application in tissue en

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Wang, Bo, Lu Han, Jun-Mei Liu, et al. "Lycium Genus Polysaccharide: An Overview of Its Extraction, Structures, Pharmacological Activities and Biological Applications." Separations 9, no. 8 (2022): 197. http://dx.doi.org/10.3390/separations9080197.

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Polysaccharide is considered to be the main active ingredient of the genus Lycium L., which is taken from the dried fruit of the famous Chinese herbal medicine and precious tonic known as wolfberry. Traditional uses include nourishing the liver and kidney and improving eyesight, with widespread use in the clinical practice of traditional Chinese medicine. Many studies have focused on the isolation and identification of the genus Lycium L. polysaccharide and its biological activities. However, the variety of raw materials and the mechanisms of polysaccharides differ. After extraction, the struc

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Kanaani, Y. M., A. Adin, and Ch Rav-Acha. "Biofilm Interactions in Water Reuse Systems: Adsorption of Polysaccharide to Kaolin." Water Science and Technology 26, no. 3-4 (1992): 673–82. http://dx.doi.org/10.2166/wst.1992.0448.

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Interactions of biofilms with dissolved and suspended aquatic matter play an important role in many water work technologies. In order to get a better insight into the driving forces for these interactions, the adsorption of polysaccharides to kaolin clay was studied. The linear adsorption coefficients, obtained at various pH levels, were all substantially lower than those obtained in other studies for humic materials(HA) at pH 6 k=60ml/g for polysaccharide, but for HA k=700ml/g. This is explained in light of the higher hydrophobicity of humic materials. The adsorption coefficient for polysacch

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Pan, Y. K., Y. H. Han, and R. Q. Huang. "Isolation and Purification of Polysaccharides from Litchi Seeds, with an Analysis of in Vitro Hypoglycemic Effect." Acta Alimentaria 49, no. 4 (2020): 365–74. http://dx.doi.org/10.1556/066.2020.49.4.1.

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Polysaccharides from litchi (Litchi chinensis) seeds were isolated and puriﬁed using ion exchange column chromatography. Molecular weight distribution of polysaccharides and monosaccharides were detected. Preliminary structural characterisation of polysaccharides was conducted using infrared, nuclear magnetic, and other spectroscopy techniques in combination with methylation analysis. In vitro cell culture experiments were designed to detect the eﬀects of polysaccharides on cell growth and cellular glucose consumption. We extracted and analysed three polysaccharides from litchi seed. Monosacch

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Silva, Inês M. V., Fernanda Machado, Maria João Moreno, Cláudia Nunes, Manuel A. Coimbra, and Filipe Coreta-Gomes. "Polysaccharide Structures and Their Hypocholesterolemic PoTential." Molecules 26, no. 15 (2021): 4559. http://dx.doi.org/10.3390/molecules26154559.

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Several classes of polysaccharides have been described to have hypocholesterolemic potential, namely cholesterol bioaccessibility and bioavailability. This review will highlight the main mechanisms by which polysaccharides are known to affect cholesterol homeostasis at the intestine, namely the effect (i) of polysaccharide viscosity and its influence on cholesterol bioaccessibility; (ii) on bile salt sequestration and its dependence on the structural diversity of polysaccharides; (iii) of bio-transformations of polysaccharides and bile salts by the gut microbiota. Different quantitative struct

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Vukojevic, Jelena, Mirjana Stajic, Sonja Duletic-Lausevic, and Jasmina Simonic. "Effect of medium pH and cultivation period on mycelial biomass, polysaccharide, and ligninolytic enzyme production by Ganoderma lucidum from Montenegro." Archives of Biological Sciences 58, no. 3 (2006): 179–82. http://dx.doi.org/10.2298/abs0603179v.

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The effect of initial medium pH on biomass, extracellular and intracellular polysaccharide, and ligninolytic enzyme production by Ganoderma lucidum was investigated at different pH values after 7 and 14 days of cultivation. Maximal production of biomass was recorded at pH 4.5 and 5.0; maximal production of extracellular polysaccharides at pH 7.0 and 3.0; and maximal production of intracellular polysaccharides at pH 7.0 and 5.5. Ligninolytic enzymes were not produced at any pH of the medium. Maximal biomass production was obtained on the 11th day of cultivation; maximal extracellular polysaccha

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Obukhanych, Tetyana V., and Michel C. Nussenzweig. "T-independent type II immune responses generate memory B cells." Journal of Experimental Medicine 203, no. 2 (2006): 305–10. http://dx.doi.org/10.1084/jem.20052036.

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Unlike T-dependent immune responses against protein antigens, T-independent responses against polysaccharides confer long-lasting humoral immunity in the absence of recall responses and are not known to generate memory B cells. Here we report that polysaccharide antigens elicit memory B cells that are phenotypically distinct from those elicited by protein antigens. Furthermore, memory B cell responses against polysaccharides are regulated by antigen-specific immunoglobulin G antibodies. As the generation and regulation of immunologic memory is central to vaccination, our findings help explain

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Cui, Feng-Jie, Li-Sun Qian, Wen-Jing Sun, et al. "Ultrasound-Assisted Extraction of Polysaccharides from Volvariella volvacea: Process Optimization and Structural Characterization." Molecules 23, no. 7 (2018): 1706. http://dx.doi.org/10.3390/molecules23071706.

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The aims of the present study were to optimize the operational parameters to maximize the yield of ultrasound-assisted polysaccharide extraction from Volvariella volvacea (straw mushroom) fruiting bodies by using for the first time one-factor-at-a-time and three-level Box-Behnken factorial designs. A maximum polysaccharide yield of 8.28 ± 0.23% was obtained under the optimized conditions of ultrasound power of 175 W, extraction temperature of 57 °C, extraction time of 33 min, and the ratio of liquid to raw material of 25:1, respectively. Compared to the hot-water extraction, the ultrasound-ass

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Chen, Zishuo, Jiayi Wu, Na Wang, et al. "Isolation, Characterization, Moisturization and Anti-HepG2 Cell Activities of a Novel Polysaccharide from Cyanobacterium aponinum." Molecules 29, no. 19 (2024): 4556. http://dx.doi.org/10.3390/molecules29194556.

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Polysaccharides from cyanobacteria are extensively reported for their complex structures, good biocompatibility, and diverse bioactivities, but only a few cyanobacterial species have been exploited for the biotechnological production of polysaccharides. According to our previous study, the newly isolated marine cyanobacterium Cyanobacterium aponinum SCSIO-45682 was a good candidate for polysaccharide production. This work provided a systematic study of the extraction optimization, isolation, structural characterization, and bioactivity evaluation of polysaccharides from C. aponinum SCSIO-45682

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Furusawa, Go, Nor Azura Azami, and Aik-Hong Teh. "Genes for degradation and utilization of uronic acid-containing polysaccharides of a marine bacterium Catenovulum sp. CCB-QB4." PeerJ 9 (March 9, 2021): e10929. http://dx.doi.org/10.7717/peerj.10929.

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Background Oligosaccharides from polysaccharides containing uronic acids are known to have many useful bioactivities. Thus, polysaccharide lyases (PLs) and glycoside hydrolases (GHs) involved in producing the oligosaccharides have attracted interest in both medical and industrial settings. The numerous polysaccharide lyases and glycoside hydrolases involved in producing the oligosaccharides were isolated from soil and marine microorganisms. Our previous report demonstrated that an agar-degrading bacterium, Catenovulum sp. CCB-QB4, isolated from a coastal area of Penang, Malaysia, possessed 183

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Bac, Vo Hoai, Tran Thi Van Anh, Nguyen Thi Mai Phuong, Nguyen Thi Thanh Huong, and Le Van Truong. "OPTIMIZED EXTRACTION AND IMMUNOSTIMULATORY EFFECTS OF POLYSACCHARIDES FROM PSEUDERANTHEMUM PALATIFERUM (NEES) RADLK." Vietnam Journal of Biotechnology 16, no. 2 (2018): 327–35. http://dx.doi.org/10.15625/1811-4989/16/2/13445.

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Pseuderanthemum palatiferum (Ness) Radlk is a tree native of Vietnam with various use in traditional medicine. It has been used for the treatment of many diseases including wound, colitis, stomach-aches, trauma, high blood pressure, nephritis, diarrhoea. However, the research on effective constituents from P. palatiferum has mainly been focused on small-molecular compounds. Some compounds: flavonoids, phytol, palmitic acid, ß-sitosterol, triterpenoid saponin, stigmasterol and salicylic acid have been detected in leaves. Polysaccharides have attracted great attentions for its benefits to human

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Sun, Yanzhen, Xiaodong Jing, Xiaoli Ma, Yinglong Feng, and Hao Hu. "Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy." International Journal of Molecular Sciences 21, no. 23 (2020): 9159. http://dx.doi.org/10.3390/ijms21239159.

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Chemotherapy is still the most direct and effective means of cancer therapy nowadays. The proposal of drug delivery systems (DDSs) has effectively improved many shortcomings of traditional chemotherapy drugs. The technical support of DDSs lies in their excellent material properties. Polysaccharides include a series of natural polymers, such as chitosan, hyaluronic acid, and alginic acid. These polysaccharides have good biocompatibility and degradability, and they are easily chemical modified. Therefore, polysaccharides are ideal candidate materials to construct DDSs, and their clinical applica

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Arnosti, C., M. Wietz, T. Brinkhoff, et al. "The Biogeochemistry of Marine Polysaccharides: Sources, Inventories, and Bacterial Drivers of the Carbohydrate Cycle." Annual Review of Marine Science 13, no. 1 (2021): 81–108. http://dx.doi.org/10.1146/annurev-marine-032020-012810.

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Polysaccharides are major components of macroalgal and phytoplankton biomass and constitute a large fraction of the organic matter produced and degraded in the ocean. Until recently, however, our knowledge of marine polysaccharides was limited due to their great structural complexity, the correspondingly complicated enzymatic machinery used by microbial communities to degrade them, and a lack of readily applied means to isolate andcharacterize polysaccharides in detail. Advances in carbohydrate chemistry, bioinformatics, molecular ecology, and microbiology have led to new insights into the str

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Qian, Lijuan, Mengxiang Du, Xiaoyan Yang, et al. "Microanalysis Characterization and Immunomodulatory Effect for Selenium-Enriched Polysaccharide from Morchella esculenta (L.) Pers." Molecules 28, no. 7 (2023): 2885. http://dx.doi.org/10.3390/molecules28072885.

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Morchella esculenta (L.) Pers., referred to as Morel, is a medicinal and edible homologous fungus, which contains many bioactive substances. In Morel, polysaccharides are the most abundant and have various bioactivities. In the present work, two novel polysaccharides, Se-MPS and MPS, were prepared and purified from selenium-enriched (Se-enriched) and common Morel mycelia, respectively, and their structural and immunomodulatory properties were evaluated. The results show that Se-enriched treatment significantly changed the polysaccharides’ chemical composition, molecular weight, and sugar chain

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