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1

Liu, Huaping, Yong Qin, Ruoyu Wang, Dongfei Zhang, and Bingxiao Lu. "The Performance of the Self-Supplying Vortex Generator Jets on a High-Speed Compressor Cascade." International Journal of Turbo & Jet-Engines 36, no. 1 (2019): 113–25. http://dx.doi.org/10.1515/tjj-2016-0056.

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Abstract The self-supplying vortex generator jet (SVGJ) is introduced to the separation control of a high-speed compressor cascade with an inlet Mach number of 0.67. A parametric investigation concerning the jet location and the injection angle is conducted numerically. The effect mechanisms of SVGJ on the cascade performance are analyzed in detail. The potentials of SVGJ at off-design points are also discussed. The vortex generated by the jet utilizing the pressure difference between the pressure surface and suction surface could enhance the fluid exchange between the boundary layer and the m
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2

Mininni, P. D., D. Rosenberg, and A. Pouquet. "Isotropization at small scales of rotating helically driven turbulence." Journal of Fluid Mechanics 699 (April 13, 2012): 263–79. http://dx.doi.org/10.1017/jfm.2012.99.

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AbstractWe present numerical evidence of how three-dimensionalization occurs at small scale in rotating turbulence with Beltrami ($\mathit{ABC}$) forcing, creating helical flow. The Zeman scale ${\ell }_{\Omega } $ at which the inertial and eddy turn-over times are equal is more than one order of magnitude larger than the dissipation scale, with the relevant domains (large-scale inverse cascade of energy, dual regime in the direct cascade of energy $E$ and helicity $H$, and dissipation) each moderately resolved. These results stem from the analysis of a large direct numerical simulation on a g
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3

Nossuli, T. O., V. Lakshminarayanan, G. Baumgarten, et al. "A chronic mouse model of myocardial ischemia-reperfusion: essential in cytokine studies." American Journal of Physiology-Heart and Circulatory Physiology 278, no. 4 (2000): H1049—H1055. http://dx.doi.org/10.1152/ajpheart.2000.278.4.h1049.

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Reperfusion of the ischemic myocardium is associated with a cytokine cascade that reflects a cellular response to injury. We studied this cascade in the mouse and found that acute surgical trauma in sham-operated animals obscured early changes in cytokine induction that occur during myocardial ischemia-reperfusion (MI/R). Therefore, we utilized a new implantable device that allows occlusion and reperfusion of the left anterior descending coronary artery in a closed-chest mouse at any time after instrumentation. Induction of interleukin (IL)-6 and tumor necrosis factor (TNF)-α mRNA in the whole
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4

Matsubara, Daiki, Takuma Kunieda, Yuhki Yanase, et al. "Time Course of Priming Effect of TF Inducers on Synergistic TF Expression and Intra-Cellular Gap Formation of Human Vascular Endothelial Cells via the Extrinsic Coagulation Cascade." International Journal of Molecular Sciences 24, no. 15 (2023): 12388. http://dx.doi.org/10.3390/ijms241512388.

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Chronic spontaneous urticaria (CSU) is characterized by daily recurring wheal and flare with itch for more than 6 weeks. The extrinsic coagulation system has been shown to be activated in correlation with CSU severity. We have reported that tissue factor (TF), a trigger of the extrinsic coagulation cascade, is synergistically expressed on vascular endothelial cells by simultaneous stimulation with TF inducers (TFI), followed by activation of the extrinsic coagulation cascade and hyper permeability in vitro. However, vascular endothelial cells are not likely to be simultaneously stimulated by m
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5

Elsasser, Ted H., Stanislaw Kahl, Carol MacLeod, Benjamin Nicholson, James L. Sartin, and Congjun Li. "Mechanisms Underlying Growth Hormone Effects in Augmenting Nitric Oxide Production and Protein Tyrosine Nitration during Endotoxin Challenge." Endocrinology 145, no. 7 (2004): 3413–23. http://dx.doi.org/10.1210/en.2004-0063.

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Abstract The present study defined the effects of GH administration on components of the nitric oxide (NO)-generating cascade to account for observed increases in NO production and protein nitration after an immune challenge. Calves were assigned to groups with or without GH treatment (100 μg GH/kg body weight or placebo im, daily for 12 d) and with or without low-level endotoxin [lipopolysaccharide (LPS), 2.5 μg/kg, or placebo, iv]. Plasma was obtained for estimation of NO changes as [NO2− + NO3−] (NOx). Transcutaneous liver biopsies were collected for measurement of protein tyrosine nitratio
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6

Grace, Marcy B., Cheng-Min Chang, Vijay K. Singh, et al. "In Vivo Induction of Cytokine mRNA and Protein in Mice by the Radioprotectant Steroid 5-Androstenediol." Blood 104, no. 11 (2004): 4224. http://dx.doi.org/10.1182/blood.v104.11.4224.4224.

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Abstract We previously showed 5-androstenediol (5-AED) injected sc enhanced survival in mice exposed to whole-body gamma-irradiation, ameliorated radiation-induced neutropenia in mice, dogs, and monkeys, and induced increases in bone marrow GM-CFC in irradiated mice. Radiation-induced decreases in platelets, natural killer cells, red blood cells, and monocytes were also blunted by the steroid. Administration of 5-AED caused functional activation of circulating granulocytes (phagocytic ability), monocytes (oxidative burst), and natural killer cells (surface CD11b expression). To test our hypoth
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7

Vítek, Petr, Barbora Veselá, and Karel Klem. "Spatial and Temporal Variability of Plant Leaf Responses Cascade after PSII Inhibition: Raman, Chlorophyll Fluorescence and Infrared Thermal Imaging." Sensors 20, no. 4 (2020): 1015. http://dx.doi.org/10.3390/s20041015.

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The use of photosystem II (PSII) inhibitors allows simulating cascade of defense and damage responses, including the oxidative stress. In our study, PSII inhibiting herbicide metribuzin was applied to the leaf of the model plant species Chenopodium album. The temporally and spatially resolved cascade of defense responses was studied noninvasively at the leaf level by combining three imaging approaches: Raman spectroscopy as a principal method, corroborated by chlorophyll a fluorescence (ChlF) and infrared thermal imaging. ChlF imaging show time-dependent transport in acropetal direction throug
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8

Park, Pierce, Mark Haas, Patrick N. Cunningham, Lihua Bao, Jessy J. Alexander, and Richard J. Quigg. "Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes." American Journal of Physiology-Renal Physiology 282, no. 2 (2002): F352—F357. http://dx.doi.org/10.1152/ajprenal.00160.2001.

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Ischemia-reperfusion injury (IRI) is a complex and incompletely understood process involving a cascade of events that culminates in apoptotic and/or necrotic cell death. Natural IgM antibodies and complement have been implicated in the pathogenesis of IRI in a variety of organ systems as have T lymphocytes in renal IRI. To investigate the role of Ig and T lymphocytes in renal IRI, recombination-activating gene (RAG)-1-deficient mice were studied. RAG-1(−/−) mice were not protected from acute renal failure induced by 27.5 min of bilateral renal ischemia and subsequent reperfusion [serum urea ni
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9

Steinmann, Andrea, Maurice Finger, Christian Nowacki, et al. "Heterologous Lignan Production in Stirred-Tank Reactors—Metabolomics-Assisted Bioprocess Development for an In Vivo Enzyme Cascade." Catalysts 12, no. 11 (2022): 1473. http://dx.doi.org/10.3390/catal12111473.

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Towards establishing a prospective industrial microbial lignan production process, we set up and investigated the biotransformation of coniferyl alcohol to secoisolariciresinol with recombinant Escherichia coli in a stirred-tank reactor (STR). Initially, we tested different cofactor concentrations and antifoam additions in shake flasks. Next, we designed an STR batch bioprocess and tested aeration rates, pH regulation, and substrate-feeding strategies. Targeted metabolomics of phenylpropanoids and lignans assisted the bioprocess development by monitoring the lignan pathway activity. We found t
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10

Smith, Stephanie A., Julie N. Collins, Sharon H. Choi, and James H. Morrissey. "Novel Polyphosphate-Binding Proteins in Human Plasma and Platelet Releasates." Blood 118, no. 21 (2011): 2270. http://dx.doi.org/10.1182/blood.v118.21.2270.2270.

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Abstract Abstract 2270 Introduction: Inorganic polyphosphates (polyP) are negatively charged, linear phosphate polymers found throughout biology. PolyP is secreted in substantial amounts by activated human platelets and it also accumulates in many infectious microorganisms. We have shown that polyP is a potent hemostatic regulator, acting at multiple points in the clotting cascade; in particular, polyP triggers the contact pathway, enhances FXI activation by thrombin, accelerates factor V activation, and modulates fibrin clot structure. Since there may be other, as-yet undiscovered (patho)phys
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11

Pillo, Gelsomina, Maria Grazia Mascolo, Cristina Zanzi, et al. "Mechanistic Interrogation of Cell Transformation In Vitro: The Transformics Assay as an Exemplar of Oncotransformation." International Journal of Molecular Sciences 23, no. 14 (2022): 7603. http://dx.doi.org/10.3390/ijms23147603.

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The Transformics Assay is an in vitro test which combines the BALB/c 3T3 Cell Transformation Assay (CTA) with microarray transcriptomics. It has been shown to improve upon the mechanistic understanding of the CTA, helping to identify mechanisms of action leading to chemical-induced transformation thanks to RNA extractions in specific time points along the process of in vitro transformation. In this study, the lowest transforming concentration of the carcinogenic benzo(a)pyrene (B(a)P) has been tested in order to find molecular signatures of initial events relevant for oncotransformation. Appli
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12

Alatas, Masrur, Maria Theresia Sri Budiastuti, Totok Gunawan, and Prabang Setyono. "Stage of Potential Identification Irrigation Channel Topography Analysis for Micro-Hydro Power in the Kalibawang Irrigation Primary Channel, Yogyakarta, Indonesia." International Journal of Sustainable Development and Planning 16, no. 5 (2021): 953–64. http://dx.doi.org/10.18280/ijsdp.160516.

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This study was designed to determine the stages in the identification of micro-hydro in irrigation channels based on the classification and level of data requirements in a project, starting from the initial study, feasibility study and detailed engineering design. The study was conducted with site selection criteria using four information systems and technology tools, namely Google Earth, GIS Topography, UAV Drone Phantom DJI 4, and Nikkon DTM 332 Total Station. The results shows through GE and GIS, obtained 23 potential points, 7 of which are high potential, followed by field measurements wit
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13

Hippchen, Yanick, Gargi Tewary, Daniela Jung, et al. "Cultured Human Foreskin as a Model System for Evaluating Ionizing Radiation-Induced Skin Injury." International Journal of Molecular Sciences 23, no. 17 (2022): 9830. http://dx.doi.org/10.3390/ijms23179830.

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Purpose: Precise molecular and cellular mechanisms of radiation-induced dermatitis are incompletely understood. Histone variant H2A.J is associated with cellular senescence and modulates senescence-associated secretory phenotype (SASP) after DNA-damaging insults, such as ionizing radiation (IR). Using ex vivo irradiated cultured foreskin, H2A.J was analyzed as a biomarker of radiation-induced senescence, potentially initiating the inflammatory cascade of radiation-induced skin injury. Methods: Human foreskin explants were collected from young donors, irradiated ex vivo with 10 Gy, and cultured
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14

Poulsen, L. C., J. A. Bøtkjær, O. Østrup, et al. "Two waves of transcriptomic changes in periovulatory human granulosa cells." Human Reproduction 35, no. 5 (2020): 1230–45. http://dx.doi.org/10.1093/humrep/deaa043.

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Abstract STUDY QUESTION How does the human granulosa cell (GC) transcriptome change during ovulation? SUMMARY ANSWER Two transcriptional peaks were observed at 12 h and at 36 h after induction of ovulation, both dominated by genes and pathways known from the inflammatory system. WHAT IS KNOWN ALREADY The crosstalk between GCs and the oocyte, which is essential for ovulation and oocyte maturation, can be assessed through transcriptomic profiling of GCs. Detailed transcriptional changes during ovulation have not previously been assessed in humans. STUDY DESIGN, SIZE, DURATION This prospective co
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15

Wang, Yifan, Leo W. Beukeboom, Bregje Wertheim, and Roelof A. Hut. "Transcriptomic Analysis of Light-Induced Genes in Nasonia vitripennis: Possible Implications for Circadian Light Entrainment Pathways." Biology 12, no. 9 (2023): 1215. http://dx.doi.org/10.3390/biology12091215.

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Circadian entrainment to the environmental day–night cycle is essential for the optimal use of environmental resources. In insects, opsin-based photoreception in the compound eye and ocelli and CRYPTOCHROME1 (CRY1) in circadian clock neurons are thought to be involved in sensing photic information, but the genetic regulation of circadian light entrainment in species without light-sensitive CRY1 remains unclear. To elucidate a possible CRY1-independent light transduction cascade, we analyzed light-induced gene expression through RNA-sequencing in Nasonia vitripennis. Entrained wasps were subjec
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16

Arun, Ashutosh, Kayla J. Rayford, Ayorinde Cooley, et al. "Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells." International Journal of Molecular Sciences 21, no. 14 (2020): 4912. http://dx.doi.org/10.3390/ijms21144912.

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The protozoan parasite Trypanosoma cruzi is the causative agent of Chagas disease. This neglected tropical disease causes severe morbidity and mortality in endemic regions. About 30% of T. cruzi infected individuals will present with cardiac complications. Invasive trypomastigotes released from infected cells can be carried in the vascular endothelial system to infect neighboring and distant cells. During the process of cellular infection, the parasite induces host cells, to increase the levels of host thrombospondin-1 (TSP-1), to facilitate the process of infection. TSP-1 plays important role
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17

Jendrossek, Verena, Sophie Fillon, Claus Belka, Ilka Müller, Beatrice Puttkammer, and Florian Lang. "Apoptotic Response of Chang Cells to Infection with Pseudomonas aeruginosa Strains PAK and PAO-I: Molecular Ordering of the Apoptosis Signaling Cascade and Role of Type IV Pili." Infection and Immunity 71, no. 5 (2003): 2665–73. http://dx.doi.org/10.1128/iai.71.5.2665-2673.2003.

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ABSTRACT Pseudomonas aeruginosa is a gram-negative facultative opportunistic pathogen associated with severe infections in immunocompromised hosts and in patients with cystic fibrosis. P. aeruginosa strains show divergent pathogenicity in vivo and trigger apoptosis of and/or are internalized into human host cells. In the present study, we studied the molecular ordering of apoptosis signaling upon infection of human conjunctiva epithelial Chang cells with P. aeruginosa PAK as well as the role of bacterial pili in the response to the infection. Our results show that CD95 up-regulation is followe
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18

Hippler, R., B. Siegmann, C. D. Lin, N. Toshima, and J. B. Wang. "Alignment of H(2p) in H+–H collisions." Canadian Journal of Physics 74, no. 11-12 (1996): 959–61. http://dx.doi.org/10.1139/p96-814.

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The integral alignment of H(2p) in H+–H collisions is re-examined. The previously observed differences between experiment and theoretical calculations cannot be attributed to cascade effects from the H(n = 3) states.
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19

Torre, María F., María Martinez-Ferran, Néstor Vallecillo, Sergio L. Jiménez, Carlos Romero-Morales, and Helios Pareja-Galeano. "Supplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review." Antioxidants 10, no. 2 (2021): 279. http://dx.doi.org/10.3390/antiox10020279.

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Muscle damage induced by exercise may have several consequences such as delayed-onset muscle soreness, a side-effect of the release of free radicals during oxidative stress. To mitigate the oxidative stress cascade, the oral intake of antioxidants has been assessed by several research groups. This review examines whether supplementation with vitamin C and/or vitamin E is able to prevent or attenuate delayed-onset muscle soreness after eccentric exercise. The PubMed, Web of Science, Medline, and Embase databases were searched to identify studies meeting the inclusion criteria: primary randomize
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20

Watt, Matthew J., and Lawrence L. Spriet. "Regulation and role of hormone-sensitive lipase activity in human skeletal muscle." Proceedings of the Nutrition Society 63, no. 2 (2004): 315–22. http://dx.doi.org/10.1079/pns2004360.

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Hormone-sensitive lipase (HSL) is believed to play a regulatory role in initiating the degradation of intramuscular triacylglycerol (IMTG) in skeletal muscle. A series of studies designed to characterise the response of HSL to three stimuli: exercise of varying intensities and durations; adrenaline infusions; altered fuel supply have recently been conducted in human skeletal muscle. In an attempt to understand the regulation of HSL activity the changes in the putative intramuscular and hormonal regulators of the enzyme have also been measured. In human skeletal muscle at rest there is a high c
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21

Zhao, Chenghan, Xiang Li, Da Xie, and Mingjie Pan. "The Inertial Energy Control Strategy of the Cascade H-Bridge Module applied in Photovoltaic System." E3S Web of Conferences 261 (2021): 01053. http://dx.doi.org/10.1051/e3sconf/202126101053.

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This paper put forward the inertial control strategy based on the control of charge and discharge of supercapacitor and the trigger angle of H-bridge which integrates photovoltaic (PV) system. The whole cascade H-bridge structure is composed of traditional photovoltaic module, Boost/Buck circuit, supercapacitor (SC), and H-bridge circuit. First, the charging state and the inertial energy power support of the SC are analysed. Then the control strategy of the cascade H-bridge is proposed. To verify the efficiency of the control strategy, a cascade chain consists of 12 H-bridge unit was built in
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22

Shi, Li Ping, Zheng Da Wang, and Ya Jing Hu. "Study of Cascade Seven-Level Parallel Active Filter." Advanced Materials Research 433-440 (January 2012): 6038–42. http://dx.doi.org/10.4028/www.scientific.net/amr.433-440.6038.

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Multi-level inverter can output high voltage directly and can be connected without transformer, so it is applied more and more widely in high power situation. This paper presents a cascade H bridge seven-level parallel active power filter. This paper analyzes the principle of cascade H bridge multi-level inverter, designs a cascade H bridge seven-level SAPF based on CPS-SPWM, and the principle and the effect are simulated. The simulation results show that this system can compensate load harmonic current.
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Lee, Seongjun, and Jonghoon Kim. "Optimized Modeling and Control Strategy of the Single-Phase Photovoltaic Grid-Connected Cascaded H-bridge Multilevel Inverter." Electronics 7, no. 9 (2018): 207. http://dx.doi.org/10.3390/electronics7090207.

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This paper presents the modeling and control-loop design method with an inverted decoupling scheme of a single-phase photovoltaic grid-connected five-level cascaded H-bridge multilevel inverter. For the unity power factor, the proportional and integral current controller with a duty ratio feed-forward compensation is used. In addition, in order to achieve the maximum power point tracking of each photovoltaic array, when the stacked modules are in the partial shading condition, each direct current (DC) voltage is stably controlled to their maximum power points (MPP) by dedicated voltage control
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24

Yao, Zhipeng, Tao Li, Muhua Cao, et al. "The Role of Circulating Neutrophils in Increased Procoagulant Activity after Acute Ischemic Stroke." Blood 128, no. 22 (2016): 3682. http://dx.doi.org/10.1182/blood.v128.22.3682.3682.

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Abstract Introduction: Acute ischemic stroke (AIS) is a hypoxic ischemic disorder associated with a sterile inflammatory reaction. Neuronal injury from ischemic stroke is aggravated by invading peripheral polymorphonuclear cells (PMNs). Neutrophils not only have a remarkable neurotoxic effect from the release of proteolytic enzymes, but also foster coagulation cascade by exposing membrane phosphatidylserine (PS), aggregating to platelets and releasing neutrophil extracellular traps (NETs). However, the role of circulating neutrophils in hypercoagulation state after AIS remains unclear. Our aim
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25

Erbe, L. H., K. Gęba, and W. Krawcewicz. "Equivariant Fixed Point Index and the Period-Doubling Cascades." Canadian Journal of Mathematics 43, no. 4 (1991): 738–47. http://dx.doi.org/10.4153/cjm-1991-042-4.

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Properties of fixed points of equivariant maps have been studied by several authors including A. Dold (cf. [2], 1982), H. Ulrich (cf. [9], 1988), A. Marzantowicz (cf. [7], 1975) and others. Closely related is the work of R. Rubinsztein (cf. [8], 1976) in which he investigated homotopy classes of equivariant maps between spheres. There have been many attempts to introduce and effectively apply these concepts to nonlinear problems. In particular we mention the work of E. Dancer (cf. [1], 1982) in which some applications to nonlinear problems are given.
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Shi, Hang, David J. Babinski, and Tobias Ritter. "Modular C–H Functionalization Cascade of Aryl Iodides." Journal of the American Chemical Society 137, no. 11 (2015): 3775–78. http://dx.doi.org/10.1021/jacs.5b01082.

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Mehta, Vaibhav P., José-Antonio García-López, and Michael F. Greaney. "Ruthenium-Catalyzed Cascade CH Functionalization of Phenylacetophenones." Angewandte Chemie 126, no. 6 (2014): 1555–59. http://dx.doi.org/10.1002/ange.201309114.

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Mehta, Vaibhav P., José-Antonio García-López, and Michael F. Greaney. "Ruthenium-Catalyzed Cascade CH Functionalization of Phenylacetophenones." Angewandte Chemie International Edition 53, no. 6 (2014): 1529–33. http://dx.doi.org/10.1002/anie.201309114.

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Dai, Xian Bin, Xiao Hua Yuan, and Wei Du. "Research of Simulation in the Main Circuit of Static Var Generator Based on Cascade H-Bride." Applied Mechanics and Materials 392 (September 2013): 409–12. http://dx.doi.org/10.4028/www.scientific.net/amm.392.409.

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This paper introduces the working principle of the research of simulation in the main circuit of Static Var Generator based on Cascade H-Bride and takes the three-phase Static Var Generator based on cascade H-Bride with rated capacity 10kVar,rated voltage 380V for example to proceed the MATLAB simulation. The research shows that the more amount of cascade H-Bride, the more number of output voltage levels in the main circuit of Static Var Generator, the smaller value of voltage waveform distortion factor, and the less harmonic content be inject in electric network, which improves power index.
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Zhang, Shuai, Yuanhong Ma, Jingbo Lan, Feijie Song, and Jingsong You. "Gold-catalyzed cascade C–H/C–H cross-coupling/cyclization/alkynylation: an efficient access to 3-alkynylpyrroles." Organic & Biomolecular Chemistry 13, no. 21 (2015): 5867–70. http://dx.doi.org/10.1039/c5ob00599j.

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Kupchishin, Anatoliy I., Alexander A. Kupchishin, Natalia A. Voronova, and Viktor M. Lisitsyn. "Cascade Probability Method and its Relationship with Boltzmann Equations." Key Engineering Materials 712 (September 2016): 123–29. http://dx.doi.org/10.4028/www.scientific.net/kem.712.123.

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The paper suggests and develops a cascade probability method (in particular, for flows of plasma particles), the essence of which is to obtain and apply cascade probability functions (CPF) to cases of different particles. CPF is the probability of particles formed at a certain depth h' reaching a certain depth h after i collisions. The work has considered the interaction of particles with matter; yielded the general solution for cascade probability method and a particular solution for the case of a collided particle not changing its direction and the flow rate not depending on time.
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Fu, Leiqing, Jie-Ping Wan, Liyun Zhou, and Yunyun Liu. "Copper-catalyzed C–H/N–H annulation of enaminones and alkynyl esters for densely substituted pyrrole synthesis." Chemical Communications 58, no. 11 (2022): 1808–11. http://dx.doi.org/10.1039/d1cc06768k.

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The synthesis of 2-vinyl pyrroles has been achieved via copper-catalyzed cascade reactions of enaminones and alkyl propiolates. The synthesis of 2,3-dicarboxylate-functionalized products has been tuned by using internal alkynyl dicarboxylates.
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Roesler, F. L., E. J. Mierkiewicz та S. M. Nossal. "The geocoronal H α cascade component determined from geocoronal H β intensity measurements". Journal of Geophysical Research: Space Physics 119, № 8 (2014): 6642–47. http://dx.doi.org/10.1002/2014ja020026.

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34

Moulick, Sanjib, Naresh V. Tambada, Basant K. Singh, and B. C. Mal. "Aeration characteristics of a rectangular stepped cascade system." Water Science and Technology 61, no. 2 (2010): 415–20. http://dx.doi.org/10.2166/wst.2010.828.

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Aeration experiments, maintaining nappe flow conditions, were carried out on a rectangular stepped cascade of total height 3.0 m to determine the total number of steps, slope of the entire cascade and hydraulic loading rate at which maximum overall aeration efficiency occurs, keeping the surface area of individual steps constant. Based on dimensional analysis, the overall aeration efficiency at standard conditions (E20) was expressed as a function of square of total number of steps (N2) and dimensionless discharge (dc/h), where dc and h represent critical depth in a rectangular prismatic chann
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Gu, Binjie, Xiaoli Yu, Zhaojun Xu, Feng Pan, and Dawei Wang. "A Single-Step Palladium-Catalysed Synthesis of Naphtho[2,3-b]Benzofuran-6,11-Diones and 2-(Hydroxyphenyl)Naphthalene-1,4-Diones." Journal of Chemical Research 41, no. 10 (2017): 564–68. http://dx.doi.org/10.3184/174751917x15045169836235.

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Palladium-catalysed competitive three-component C–H functionalisation reactions and cascade coupling ring-closing reactions of quinones with iodophenols in dihaloalkanes are described. During initial attempts to conduct C–H functionalisation reactions of quinones with iodophenols in dihaloalkanes, surprisingly a three-component C–H functionalisation reaction was discovered. Furthermore, as the reaction of chloroquinones with iodophenols was in progress, another surprising cascade coupling with ring closure was achieved. This provided an efficient single-step synthesis of naphtho[2,3- b]benzofu
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Nagl, Prarthana, Sharma C S, Manoj Hirani, and Phulambrikar S. "Cascade H-Bridge Multilevel Inverter Fed Induction Motor Drive." IJIREEICE 5, no. 1 (2017): 32–35. http://dx.doi.org/10.17148/ijireeice.2017.5107.

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Zhang, Zeyuan, Zhen Dai, Xinkun Ma, et al. "Cu-catalyzed one-pot synthesis of fused oxazepinone derivatives via sp2 C–H and O–H cross-dehydrogenative coupling." Organic Chemistry Frontiers 3, no. 7 (2016): 799–803. http://dx.doi.org/10.1039/c6qo00040a.

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Luo, Liangliang, Xiao-Pan Chen, Zhao-Feng Li, Yuan Zhou, You-Cai Xiao, and Fen-Er Chen. "Palladium(ii)-catalyzed aerobic oxidative O–H/C–H isocyanide insertion: facile access to pyrrolo[2,1-c][1,4]benzoxazine derivatives." Organic & Biomolecular Chemistry 19, no. 19 (2021): 4364–68. http://dx.doi.org/10.1039/d1ob00393c.

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Ghosn, Youssef, Mohammed Hussein Kamareddine, Antonios Tawk, et al. "Analysis of gastric and duodenal biopsy results in patients presenting with dyspepsia: a cross-sectional study in a middle eastern population." BMJ Open Gastroenterology 6, no. 1 (2019): e000330. http://dx.doi.org/10.1136/bmjgast-2019-000330.

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ObjectiveCorrea’s cascade is a ‘Model for Gastric Cancer Development’ described by Peleyo Correa. The reversibility of Correa’s cascade remains debatable. The literature contains insufficient data on the specific stage of the cascade during which Helicobacter pylori is detected, treated, and the effect on prognosis. Herein, we aim to determine the prevalence of various precancerous and cancerous gastric lesions in patients presenting with dyspepsia, the prevalence of gastritis and H. pylori infection, the prevalence of duodenal pathology in patients presenting with dyspepsia, identify the stag
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Thombal, Raju S., Mohammad Aslam, Sonaimuthu Mohandoss, and Yong Rok Lee. "Rhodium-catalyzed cascade C–H activation/annulation/1,6-acyl migration: direct construction of free N–H indoles under mild conditions." New Journal of Chemistry 46, no. 13 (2022): 6126–33. http://dx.doi.org/10.1039/d2nj00508e.

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Fu, Lan Fang, He Xu Sun, and Yan Cai Zhu. "Sample Time Staggered One-Cycle Control Based on Three-Phase H-Bridge Cascade VSI." Advanced Materials Research 516-517 (May 2012): 1822–26. http://dx.doi.org/10.4028/www.scientific.net/amr.516-517.1822.

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The One-Cycle Control(OCC) technique not only provides fast dynamic response, but also can admirably suppress the perturbation yielded by dc source and eliminate the undesired harmonic contents.The cascade H-bridge VSI has very low dv/dt and distortion in the voltage output waveform.Sample time staggered one-cycle control(STS-OCC) based on three-phase H-bridge cascade VSI is proposed. It yields all of the advantages of the OCC and cascade VSI.The results of the simulation and analysis show that the STS-OCC technology has high equivalent work frequency, little switching loss and quick dynamic r
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Chen, Chao, Yu Hao, Ting-Yu Zhang, et al. "Computational and experimental studies on copper-mediated selective cascade C–H/N–H annulation of electron-deficient acrylamide with arynes." Chemical Communications 55, no. 6 (2019): 755–58. http://dx.doi.org/10.1039/c8cc08708c.

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Gao, Qian-Ci, Yi-Fei Li, Jun Xuan, and Xiao-Qiang Hu. "Practical synthesis of isocoumarins via Rh(III)-catalyzed C–H activation/annulation cascade." Beilstein Journal of Organic Chemistry 19 (January 30, 2023): 100–106. http://dx.doi.org/10.3762/bjoc.19.10.

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Herein, we report an unprecedented Rh(III)-catalyzed C–H activation/annulation cascade of readily available enaminones with iodonium ylides towards the convenient synthesis of isocoumarins. This coupling system proceeds in useful chemical yields (up to 93%) via a cascade C–H activation, Rh-carbenoid migratory insertion and acid-promoted intramolecular annulation. The success of gram-scale reaction and diverse functionalization of isocoumarins demonstrated the synthetic utility of this protocol.
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Zhang, Qijing, Qianrong Li та Chengming Wang. "Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone". RSC Advances 11, № 21 (2021): 13030–33. http://dx.doi.org/10.1039/d1ra01779a.

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Lin, Binzhou, Shanshan Shi, Yiqun Cui, Yupei Liu, Guo Tang, and Yufen Zhao. "Oxidative C(sp3)–H amidation of tertiary arylamines with nitriles." Organic Chemistry Frontiers 5, no. 19 (2018): 2860–63. http://dx.doi.org/10.1039/c8qo00794b.

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46

Wang, Rui, and J. R. Falck. "Ruthenium catalyzed oxidative annulation with alkynes via cascade C–H/N–H bond functionalizations." Journal of Organometallic Chemistry 759 (June 2014): 33–36. http://dx.doi.org/10.1016/j.jorganchem.2014.02.014.

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Kizaka-Kondoh, S., K. Sato, K. Tamura, H. Nojima, and H. Okayama. "Raf-1 protein kinase is an integral component of the oncogenic signal cascade shared by epidermal growth factor and platelet-derived growth factor." Molecular and Cellular Biology 12, no. 11 (1992): 5078–86. http://dx.doi.org/10.1128/mcb.12.11.5078-5086.1992.

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Our recent studies with cell mutants indicate that a cascade shared by the epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) signals exists in NRK cells and mediates oncogenic signals induced by many oncogenes (A. Masuda, S. Kizaka-Kondoh, H. Miwatani, Y. Terada, H. Nojima, and H. Okayama, New Biol. 4:489-503, 1992). We have employed the antisense RNA technique to investigate possible involvement of Raf-1 kinase in this signal transduction cascade. NRK cell clones highly reduced in the Raf-1 production are generated by the expression of a c-raf-1 antisense RNA. They have
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Kizaka-Kondoh, S., K. Sato, K. Tamura, H. Nojima, and H. Okayama. "Raf-1 protein kinase is an integral component of the oncogenic signal cascade shared by epidermal growth factor and platelet-derived growth factor." Molecular and Cellular Biology 12, no. 11 (1992): 5078–86. http://dx.doi.org/10.1128/mcb.12.11.5078.

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Our recent studies with cell mutants indicate that a cascade shared by the epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) signals exists in NRK cells and mediates oncogenic signals induced by many oncogenes (A. Masuda, S. Kizaka-Kondoh, H. Miwatani, Y. Terada, H. Nojima, and H. Okayama, New Biol. 4:489-503, 1992). We have employed the antisense RNA technique to investigate possible involvement of Raf-1 kinase in this signal transduction cascade. NRK cell clones highly reduced in the Raf-1 production are generated by the expression of a c-raf-1 antisense RNA. They have
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Arabuli, Lili, Igor A. Iashchishyn, Nina V. Romanova, et al. "Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly." International Journal of Molecular Sciences 22, no. 16 (2021): 8556. http://dx.doi.org/10.3390/ijms22168556.

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The amyloid cascade is central for the neurodegeneration disease pathology, including Alzheimer’s and Parkinson’s, and remains the focus of much current research. S100A9 protein drives the amyloid-neuroinflammatory cascade in these diseases. DOPA and cyclen-based compounds were used as amyloid modifiers and inhibitors previously, and DOPA is also used as a precursor of dopamine in Parkinson’s treatment. Here, by using fluorescence titration experiments we showed that five selected ligands: DOPA-D-H-DOPA, DOPA-H-H-DOPA, DOPA-D-H, DOPA-cyclen, and H-E-cyclen, bind to S100A9 with apparent Kd in t
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Dongbang, Sun, Blaine Pedersen, and Jonathan A. Ellman. "Asymmetric synthesis of (−)-naltrexone." Chemical Science 10, no. 2 (2019): 535–41. http://dx.doi.org/10.1039/c8sc03748e.

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