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Journal articles on the topic 'Poor Ovarian Reserve'

Author: Grafiati

Published: 2 June 2025

Last updated: 19 July 2025

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1

Jirge, PadmaRekha. "Poor ovarian reserve." Journal of Human Reproductive Sciences 9, no. 2 (2016): 63. http://dx.doi.org/10.4103/0974-1208.183514.

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Kaul - Mahajan, Nalini. "Management of Poor Ovarian Response." Fertility & Reproduction 05, no. 04 (2023): 307. http://dx.doi.org/10.1142/s2661318223741218.

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Poor ovarian response (POR) occurs in approximately 9-24% of patients in ART. It presents a challenge to the reproductive consultant and causes immense emotional distress to the couple. Over the last few decades, ART has seen an improvement on both the clinical and embryological front however, adequate management of POR remains elusive. Etio-pathogenesis of the condition is poorly understood and varying definitions of POR have been used in studies. In recent years the POSEIDON criteria have been proposed to define this group of ‘low-prognosis’ patients and to optimize management. POSEIDON grou

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Sibincic, S., D. Milacic, N. Jovanic, N. Lazic, A. Rodic, and T. Pavlovic. "Testing ovarian reserve with “poor responders”." International Journal of Gynecology & Obstetrics 70 (2000): B34—B35. http://dx.doi.org/10.1016/s0020-7292(00)86199-8.

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Sanverdi, Ilhan, Enis Ozkaya, Suna Kucur, Dilsat Bilen, Meryem Eken, and Bulent Bilgic. "Antral Follicle Diameter Variance Within Each Ovary May Be A Predictor For Poor Response In Cases With Normal Ovarian Reserve." Experimental and Clinical Endocrinology & Diabetes 126, no. 08 (2018): 521–27. http://dx.doi.org/10.1055/s-0043-125404.

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Abstract Objectives To determine the predictive value of antral follicle diameter variance within each ovary for ovarian response in cases with normal ovarian reserve tests. Methods This is a prospective observational study. One hundred and thirty nine infertile women who underwent ART in IVF-ICSI unit of Zeynep Kamil women and children’s Health Training and research hospital between January 2017 to June 2017 were recruited. Blood samples were collected on day 2/day 3 for assessment of serum FSH and estradiol. Trans-vaginal sonography was done for antral follicle count. During antral follicle

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Pandey, Divya Gupta Monika. "Poor Ovarian Response: Diagnosis And Management." British Journal of Pharmaceutical and Medical Research 04, no. 02 (2019): 1770–77. https://doi.org/10.24942/bjpmr.2019.487.

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Management of women with poor ovarian response is a challenging task for reproductive medicine clinicians, which limits the success of any treatment modality. The approach should rather be identification of expected poor responders and plan the stimulation protocol accordingly. In addition, these women should receive appropriate counselling and adequate psychological support too. Case based approach can help in effective management

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Dubinskaya, E. D., A. S. Gasparov, N. V. Dmitrieva, and N. M. Krylova. "Intraovarian autoplasmotherapy in patients with diminished ovarian reserve." Voprosy ginekologii, akušerstva i perinatologii 20, no. 6 (2021): 72–80. http://dx.doi.org/10.20953/1726-1678-2021-6-72-80.

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Objective. To evaluate the efficacy of Intraovarian autoplasmotherapy (platelet-rich plasma/PRP) in the activation of ovarian function in patients with diminished ovarian reserve and “poor” response in the in vitro fertilization (IVF) cycles, as well as its influence on the quality of life. Patients and methods. A total of 120 patients with diminished ovarian reserve and a history of IVF cycle failure who refused to use donor oocytes were included in the study. All patients underwent intraovarian PRP therapy based on the proprietary technology. The quality of life, the ovarian function, and th

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Baker, Katherine M., Rodolfo FernandezCriado, Jennifer L. Eaton, and Virginia A. Mensah. "The Clinical Utility of Measures of Ovarian Reserve." Obstetrical & Gynecological Survey 80, no. 2 (2025): 121–33. https://doi.org/10.1097/ogx.0000000000001362.

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Importance Measures of ovarian reserve, particularly anti-Müllerian hormone, have been increasingly and inaccurately utilized as “fertility tests.” It is important to understand the available measures of ovarian reserve and how to appropriately interpret and integrate their use into clinical practice. Objective The objectives of this article are to review the process of reproductive aging, define ovarian reserve, describe the available measures of ovarian reserve, and discuss the clinical utility of these measures. Evidence Acquisition A literature search was performed using the electronic dat

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Dr Vipin Kumar, Dr Kasturi R Nath, Dr Swati Dongre, Dr Asem Tokenova, and Dr Nargis Ashurova. "Effect of intra ovarian injection of platelet rich plasma to patients with diminished ovarian reserve (DOR)- A Prospective Study." IAR Journal of Medicine and Surgery Research 3, no. 5 (2022): 7–11. http://dx.doi.org/10.47310/iarjmsr.2022.v03i05.02.

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Background: Diminished ovarian reserve (DOR) is among the common findings in infertile women with no significant underlying condition especially women with advanced age. The aim of this study was to investigate the intra-ovarian potential of platelet-rich plasma (PRP) administration on oocytesdependent variables in the DOR women. A few years ago, we used intrauterine PRP injection in patients with recurrent implantation failure (RIF) which led to noticeable findings. Nowadays, PRP is used more widely in reproductive medicine due to its regenerative potentials; however, not enough data is avail

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Uddin, Muhammad J., Jesmine Banu, Shakeela Ishrat, et al. "Effect of autologous platelet rich plasma on anti-mullerian hormone and antral follicle count in sub fertile women with poor ovarian reserve." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 2 (2022): 292. http://dx.doi.org/10.18203/2320-1770.ijrcog20220033.

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Background: Ovarian aging may be reversible. Platelet rich plasma (PRP) has growth factors that promote cellular proliferation and folliculogenesis. Recently published studies and case reports suggest that ovarian rejuvenation can be done by PRP treatment. The objective of the study was to evaluate the effect of platelet rich plasma on ovarian reserve markers such as anti mullerian hormone (AMH) and antral follicle count (AFC) in sub fertile women with poor ovarian reserve (POR).Methods: The self-controlled quasi experimental study was carried out on 29 sub fertile women with poor ovarian rese

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Anwar, Sadia, Sadia Shamsher, Sadaf Saifullah, Amna Javed, Kalsoom Essa Bhettani, and Sajjad Ahmad. "Prevalence of Diminished Ovarian Reserve in Sub-fertile Women Under 40 years of Age." Annals of Punjab Medical College 17, no. 4 (2023): 427–30. http://dx.doi.org/10.29054/apmc/2023.1228.

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Background: Diminished ovarian reserve defined as when woman ovaries lose their reproductive potential in terms of quality and quantity of eggs leading to reduced fecundability and poor ovarian response to stimulation. Female age is most common prognostic element but diminished ovarian reserve is quite common under 40 years old young sub-fertile women. It is best assessed by hormonal tests like FSH and AMH levels. Objective: To assess the prevalence of diminished ovarian reserve among sub-fertile women under 40 years age. Study Design: Cross sectional study. Settings: Department of Obstetrics

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Xu, Huiyu, Li Shi, Guoshuang Feng, et al. "An Ovarian Reserve Assessment Model Based on Anti-Müllerian Hormone Levels, Follicle-Stimulating Hormone Levels, and Age: Retrospective Cohort Study." Journal of Medical Internet Research 22, no. 9 (2020): e19096. http://dx.doi.org/10.2196/19096.

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Background Previously, we reported a model for assessing ovarian reserves using 4 predictors: anti-Müllerian hormone (AMH) level, antral follicle count (AFC), follicle-stimulating hormone (FSH) level, and female age. This model is referred as the AAFA (anti-Müllerian hormone level–antral follicle count–follicle-stimulating hormone level–age) model. Objective This study aims to explore the possibility of establishing a model for predicting ovarian reserves using only 3 factors: AMH level, FSH level, and age. The proposed model is referred to as the AFA (anti-Müllerian hormone level–follicle-sti

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Choi, Tae-Young, Ji Hee Jun, Hye Won Lee, et al. "Korean medicines for poor ovarian reserve in infertility." Medicine 98, no. 44 (2019): e17731. http://dx.doi.org/10.1097/md.0000000000017731.

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Cedars, Marcelle I. "Managing poor ovarian response in the patient with diminished ovarian reserve." Fertility and Sterility 117, no. 4 (2022): 655–56. http://dx.doi.org/10.1016/j.fertnstert.2022.02.026.

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S, Gangothri. "Revitalizing Ovarian Function: Autologous Stem Cell Therapy in Poor Ovarian Reserve." Asian Research Journal of Gynaecology and Obstetrics 7, no. 1 (2024): 145–52. https://doi.org/10.9734/arjgo/2024/v7i1221.

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Faraj, Radwan, Yegu Palaniappan, and M. Kasmi. "Successful clinical pregnancy in a poor ovarian responder- A multipronged approach." Obstetrics & Gynecology International Journal 15, no. 4 (2024): 151–53. http://dx.doi.org/10.15406/ogij.2024.15.00752.

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A 38-year-old woman presented with secondary infertility persisting for four years, having previously conceived a child twelve years ago. Her medical history included bilateral ovarian cystectomies due to large dermoids. Investigations revealed a significantly reduced ovarian reserve, indicated by an AMH level of 0.50 ng/mL and FSH of 15. Her partner demonstrated satisfactory semen parameters. Initial attempts at ovarian stimulation with clomiphene citrate were unsuccessful, prompting a transition to in vitro fertilization (IVF) due to the patient's age and diminished ovarian reserve. However,

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Gorkem, Umit, Ferit Kucukler, Cihan Togrul, and Şebnem Gulen. "Obesity Does not Compromise Ovarian Reserve Markers in Infertile Women." Geburtshilfe und Frauenheilkunde 79, no. 01 (2019): 79–85. http://dx.doi.org/10.1055/a-0650-4723.

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Abstract Introduction In the literature, conflicting results from studies examining the relationship between obesity and ovarian reserve have been reported. The purpose of the study is to investigate whether obesity adversely affects serum concentrations of ovarian reserve markers in infertile women with different ovarian reserve status. Materials and Methods A total of 402 women were assigned to three groups according to body mass index (BMI; < 25 kg/m2: normal, n = 198; 25.0 – 29.9 kg/m2: overweight, n = 126; and ≥ 30 kg/m2: obese, n = 78). The women were also divided into two groups acco

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Case series on ovarian PRP and its effect on IVF outcomes." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 3 (2024): 56–60. https://doi.org/10.5281/zenodo.15407393.

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<strong>Abstract</strong> Poor ovarian reserve is one of the most challenging causes in IVF. It greatly affects the success rate .PRP (Platelet Rich Plasma) is a component of blood which contains numerous growth factor and cytokines which has shown promising result in regenerative medicine .This case series comprise of three cases with low ovarian reserve who were offered ultrasound guided ovarian PRP(Platelet Rich Plasma) before undergoing IVF stimulation. Case selection was done with strict criteria .Ovarian PRP was done on day 6 or day 7 of cycle preceding IVF stimulation .20 ml of blood sa

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Arora, Mala, and Mandeep Kaur. "Diminished Ovarian Reserve, Causes, Assessment and Management." International Journal of Infertility & Fetal Medicine 4, no. 2 (2013): 45–55. http://dx.doi.org/10.5005/jp-journals-10016-1060.

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ABSTRACT Diminished ovarian reserve predicts diminished ovarian response to stimulation but does not predict cycle fecundity. It has been recently defined by ESHRE, the Bologna's criteria, according to which at least two of the following three features should be present: (1) Age >40 years/any other risk factor for DOR, (2) abnormal ovarian reserve test, i.e. antral follicle count, AMH, (3) poor ovarian response in a previous stimulated cycle, i.e. less than three follicles after standard gonadotropin stimulation. Poor response to maximal stimulation on two previous occasions also defines DO

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Sa’diah, Yasmin Sabina, Agung Dewanto, and Lukman Ade Chandra. "#98 : Autologous Platelet-Rich Plasma Administration’s Efficacy in Patients with Low Ovarian Reserve: A Systematic Review and Meta-Analysis." Fertility & Reproduction 05, no. 04 (2023): 718–20. http://dx.doi.org/10.1142/s2661318223744272.

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Background and Aims: Autologous platelet-rich plasma (PRP) as a novel therapeutic approach has been utilized in multiple aspects of medicine because it contains stem cells and growth factors. There is still controversy over the effectiveness of this strategy in managing infertile women with low ovarian reserve due to the lack of evidence-based studies. This study aimed to systematically investigate and meta-analyze the best available evidence from clinical trials evaluating the impact of autologous platelet-rich plasma on low ovarian reserve. Methods: Systematic searches in electronic database

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Cohen, J., N. Chabbert-Buffet, and E. Darai. "Diminished ovarian reserve, premature ovarian failure, poor ovarian responder—a plea for universal definitions." Journal of Assisted Reproduction and Genetics 32, no. 12 (2015): 1709–12. http://dx.doi.org/10.1007/s10815-015-0595-y.

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Vora, Amishi Vijay, Purnima Nadkarni, Pooja Nadkarni Singh, Vaibhav Nadkarni, and Aditi Nadkarni. "Case reports for embryo banking: for women who want their own." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 7 (2019): 2926. http://dx.doi.org/10.18203/2320-1770.ijrcog20193072.

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Out of the many challenges in management of female factor infertility, poor responders and low response to stimulation in aged and even younger women, seems to be a common problem. It is very difficult to offer one particular management strategy or treatment protocol for optimum outcome in this group of women of poor responders. In a low resource set up, IVF (In vitro Fertilization) specialist doctors usually face a challenge in treating women with poor/ low ovarian reserve as ovum / gamete donation is considered as a taboo in various sections of society even today. Hence women insist on havin

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Girsh, E., A. Harlev, and L. Grin. "IN-VITRO ACTIVATION OF OVARIAN FOLLICULAR RESIDUAL RESERVE." Reproductive Medicine, no. 4(45) (December 20, 2020): 25–28. http://dx.doi.org/10.37800/rm2020-1-34.

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The newly developed in-vitro activation (IVA) method provides a novel fertility treatment for patients with premature ovarian insufficiency. The IVA method pretends to promote growth of residual ovarian follicles at early stages of their development. Based on preliminary data, poor ovarian response (POR) patients with decreased ovarian reserve (DOR) who have multiple secondary follicles, IVA is a promising technique to promote growth of secondary follicle as well.

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Scantamburlo, Viviane Margareth, Renate von Linsingen, Lidio Jair Ribas Centa, et al. "Association between decreased ovarian reserve and poor oocyte quality." Obstetrics & Gynecology Science 64, no. 6 (2021): 532–39. http://dx.doi.org/10.5468/ogs.20168.

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Objective To analyze the association between oocyte quality and decreased ovarian reserve (DOR) markers in young women undergoing controlled ovarian stimulation (COS).Methods This retrospective study included 49 patients classified as having DOR based on anti-Müllerian hormone (AMH) levels, follicle-stimulating hormone (FSH) levels, or antral follicle counts (AFCs; <10). Images of all obtained oocytes were analyzed, and oocyte quality was classified according to maturity and morphology. The COS protocol utilized gonadotropin (FSH and/or human menopausal gonadotropin [hMG]) doses ranging fro

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Younis, J. S., A. Skournik, O. Radin, S. Haddad, S. Bar-Ami, and M. Ben-Ami. "Poor oocyte retrieval − A manifestation of low ovarian reserve." Fertility and Sterility 82 (September 2004): S141. http://dx.doi.org/10.1016/j.fertnstert.2004.07.359.

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Strelko, G. V. "Anatomo-functional state of organs of small tangs in poor responders." HEALTH OF WOMAN, no. 6(132) (July 30, 2018): 50–54. http://dx.doi.org/10.15574/hw.2018.132.50.

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The objective: study of the anatomical and functional status of the uterus and ovaries in poor responders in ART programs. Materials and methods. Determination of the anatomical features and functional status of the uterus and ovaries in «poor responders» to exclude a clinically significant pathology that would affect the success of the ART program was performed by ultrasound scanning with the study of topografts, sizes, contours, echostructure of the uterus and ovary and determination of the volume of the ovaries and the number of antral follicles. Blood flow in the vessels of the stroma of t

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Zotov, S. V., V. V. Likhacheva, P. Yu Motyreva, O. V. Azarova, and B. I. Ayzikovich. "Risk factors for diminished ovarian reserve in women: Current state of the problem." Acta Biomedica Scientifica 9, no. 3 (2024): 69–78. http://dx.doi.org/10.29413/abs.2024-9.3.6.

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Ovarian reserve is the basis of female fertility. The main markers of ovarian reserve are the level of anti-Mullerian hormone and the number of antral follicles. In addition to the natural age-related loss of follicles, many women experience a premature diminished ovarian reserve associated with a number of factors. This can be caused by both various diseases and environmental factors, lifestyle, and social aspects.The aim of this review was to examine the influence of external factors on the ovarian reserve and women fertility. A systematic analysis of data from modern scientific literature,

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Elprince, Mohamed, Eman A. Kishk, Ola M. Metawie, and Magda M. Albiely. "Ovarian stimulation after dehydroepiandrosterone supplementation in poor ovarian reserve: a randomized clinical trial." Archives of Gynecology and Obstetrics 302, no. 2 (2020): 529–34. http://dx.doi.org/10.1007/s00404-020-05603-5.

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Gopinath, P. M., and Sahityalakshmi Manoharan. "Comparison of Trans-Resveratrol (98% Pure) with Resveratrol (40%) as Rejuvenation Therapy on Ovarian Reserve Parameters and Pregnancy Outcomes in Infertile Adult Women with Poor Ovarian Reserve, Undergoing Assisted Conception Cycles – A Double Arm, Randomized, Open Label Study." Scholars Journal of Applied Medical Sciences 11, no. 12 (2023): 2049–52. http://dx.doi.org/10.36347/sjams.2023.v11i12.010.

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This is a Phase IV Randomized, double arm Open labelled trial, conducted at SIMS hospital, Vadapalani, Chennai. It involves all women seeking fertility treatment with poor ovarian reserve, who are planned to undergo assisted conception cycles, including IUI & IVF. The study included women aged between 21 and 45 years, with Poor ovarian reserve with regular menstrual cycles (21–35 days), prestimulation parameters (AFC<5, AMH<1.2 ng/ml), History of previous poor ovarian response </= 5 oocytes with a conventional stimulation protocol, Couples undergoing the ICSI cycle with ejaculated

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Bernabeu, Rafael, José A. Ortiz, and Belén Lledó. "Exploring the epigenetic profile of women with poor ovarian reserve." Fertility and Sterility 115, no. 3 (2021): 599–600. http://dx.doi.org/10.1016/j.fertnstert.2020.12.023.

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Younis, Johnny S., Alex Skournik, Orit Radin, Sami Haddad, Shalom Bar-ami, and Moshe Ben-ami. "Poor oocyte retrieval is a manifestation of low ovarian reserve." Fertility and Sterility 83, no. 2 (2005): 504–7. http://dx.doi.org/10.1016/j.fertnstert.2004.09.021.

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Suyama, Julie A., Katherine E. Cameron, Mary D. Sammel, and Clarisa R. Gracia. "Pregnancies in cancer survivors: ovarian reserve is a poor prognosticator." Fertility and Sterility 112, no. 3 (2019): e21. http://dx.doi.org/10.1016/j.fertnstert.2019.07.188.

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Vladimirov, Iavor K., Desislava M. Tacheva, Krassimir B. Kalinov, Aneta V. Ivanova, and Victoria D. Blagoeva. "Prognostic value of some ovarian reserve tests in poor responders." Archives of Gynecology and Obstetrics 272, no. 1 (2005): 74–79. http://dx.doi.org/10.1007/s00404-004-0713-z.

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Boudry, Liese, Annalisa Racca, Herman Tournaye, and Christophe Blockeel. "Type and dose of gonadotropins in poor ovarian responders: does it matter?" Therapeutic Advances in Reproductive Health 15 (January 2021): 263349412110242. http://dx.doi.org/10.1177/26334941211024203.

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Infertile patients with a diminished ovarian reserve, also referred to as poor ovarian responders, constitute a substantial and increasing population of patients undergoing in vitro fertilization. The management of patients with poor ovarian response is still a controversial issue. Almost a century has passed since the introduction of the first gonadotropin. A broad collection of urinary and recombinant gonadotropins, including biosimilars, is commercially available now. Despite great advances in assisted reproductive technology, there remains uncertainty about the optimal treatment regimen fo

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Kaminskiy, A. V., O. O. Chayka та N. V. Yesyp. "Current view оn protocols of controlled ovarian hyperstimulation in women of reproductive age with different ovarian reserve". HEALTH OF WOMAN, № 9-10(155-156) (30 грудня 2020): 11–18. http://dx.doi.org/10.15574/hw.2020.155-156.11.

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Reproductology is one of the most dynamically developing branches of modern medical science. It becomes especially important in the context of changes of recent years in society, the main of which is the postponement of childbirth compared to previous generations. In addition, such an important and multifactorial problem as infertility encourages scientists to find different ways to overcome it, taking into account the number of etiological factors and different initial reproductive potential of each member of the couple. In vitro fertilization (IVF) can comprehensively solve the problem, as t

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Arpitha, M. U., B. M. Bhavya, and A. G. Athira. "Infertility Due to Low Ovarian Reserve – Treated by Matra basti-A Case Report." Indian Journal of Ayurveda and Integrative Medicine KLEU 4, no. 2 (2023): 75–78. http://dx.doi.org/10.4103/ijaim.ijaim_27_23.

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ABSTRACT Reduction in quantity and quality of oocytes due to poor ovarian reserve is an important cause of infertility in many couples of reproductive age groups. Evaluating ovarian reserve and individualizing the therapeutic strategies are very important for optimizing the success rate. A 35-year-old female presented with difficulty in conception for 4 years. She was diagnosed with primary infertility due to a low anti-Mullerian hormone (AMH) level in a modern hospital. She was given assisted reproductive treatments at various hospitals and was not successful. Hence, the patient approached ou

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Banu, Jesmine, Mostafa M., Nishat Jahan, et al. "Efficacy of autologous platelet rich plasma for ovarian rejuvenation in infertile women having poor ovarian reserve." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 11 (2022): 2948. http://dx.doi.org/10.18203/2320-1770.ijrcog20222782.

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Background: Poor ovarian reserve (POR) is a condition in which the ovary loses its normal reproductive potential and compromising fertility. Normal function of the ovaries and adequate good quality follicles are responsible for the reproductive process of a woman. Various treatment methods exist for POR, but the present study was conducted to observe the effectiveness of platelet rich plasma infusion through measurement of AMH and AFC values and pregnancy outcomes.Methods: This prospective observational study was done in the department of reproductive endocrinology and infertility from July 20

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Kim, Jihyun, Hoyoung Lee, Tae-Young Choi, et al. "Acupuncture for Poor Ovarian Response: A Randomized Controlled Trial." Journal of Clinical Medicine 10, no. 10 (2021): 2182. http://dx.doi.org/10.3390/jcm10102182.

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Acupuncture is believed to improve ovarian reserve and reproductive outcomes in women undergoing in vitro fertilization (IVF). This study was conducted to evaluate the effect of network-optimized acupuncture followed by IVF on the oocyte yield in women showing a poor ovarian response. This study was an exploratory randomized controlled trial conducted from June 2017 to January 2020 at the Pusan National University Hospital. Women diagnosed with poor ovarian response were enrolled and randomly divided into two groups: IVF alone and Ac + IVF groups (16 acupuncture sessions before IVF treatment).

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Holton, Rebecca A., Abigail M. Harris, Barenya Mukerji, Tanu Singh, Ferdusy Dia, and Karen M. Berkowitz. "CHTF18 ensures the quantity and quality of the ovarian reserve†." Biology of Reproduction 103, no. 1 (2020): 24–35. http://dx.doi.org/10.1093/biolre/ioaa036.

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Abstract The number and quality of oocytes, as well as the decline in both of these parameters with age, determines reproductive potential in women. However, the underlying mechanisms of this diminution are incompletely understood. Previously, we identified novel roles for CHTF18 (Chromosome Transmission Fidelity Factor 18), a component of the conserved Replication Factor C-like complex, in male fertility and gametogenesis. Currently, we reveal crucial roles for CHTF18 in female meiosis and oocyte development. Chtf18−/− female mice are subfertile and have fewer offspring beginning at 6 months

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MH, Mostafa, Nganjo Kuva Endeley, and Ahmed MHAM Mostafa. "Conventional IVF versus modified natural IVF for poor ovarian reserve patients." Women's Health 8, no. 6 (2019): 310–13. http://dx.doi.org/10.15406/mojwh.2019.08.00256.

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Tabs, Dunja, and Nebojsa Radunovic. "Role of maternal and paternal age in an assisted reproductive program." Medical review 55, no. 11-12 (2002): 535–38. http://dx.doi.org/10.2298/mpns0212535t.

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Introduction Many infertile couples try to become parents spontaneously, neglecting the possibility to conceive artificially, so they seek medical help in their late reproductive age. Maternal age Major aspects of maternal age in regard to assisted reproduction consider oocytes, ovaries and endometrium. Also, some habits and maternal diseases associated with aging may have an impact on fertility (smoking, atherosclerosis, previous gynecological operations etc.). Even though estimating the ovarian reserve is the most objective test in assessing female fertility, it has a limited predictive valu

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Spremovic-Radjenovic, Svetlana, Jovan Bila, Aleksandra Gudovic, Snezana Vidakovic, Milan Dokic, and Nebojsa Radunovic. "Poor ovarian response to stimulation for in vitro fertilization." Srpski arhiv za celokupno lekarstvo 143, no. 5-6 (2015): 354–61. http://dx.doi.org/10.2298/sarh1506354s.

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The term ?poor respond (POR) patients? is used for the group of women who respond badly to usual doses of gonadotropins in in vitro fertilization (IVF) treatments; the consequence is low pregnancy rate. A consensus was reached on the minimal criteria needed to define POR. At least two of the following three features must be present: 1. advanced maternal age (40 years or more) 2. previous POR (3 or less oocytes with a conventional stimulation protocol) 3. abnormal ovarian reserve (AMH 0.5-1.1 ng/ml or AFC 5-7). The aim is to find better therapeutic options for these patients. Increased levels o

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Martirosyan, Yana O., Denis N. Silachev, Tatiana A. Nazarenko, Almina M. Birukova, Polina A. Vishnyakova, and Gennadiy T. Sukhikh. "Stem-Cell-Derived Extracellular Vesicles: Unlocking New Possibilities for Treating Diminished Ovarian Reserve and Premature Ovarian Insufficiency." Life 13, no. 12 (2023): 2247. http://dx.doi.org/10.3390/life13122247.

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Despite advancements in assisted reproductive technology (ART), achieving successful pregnancy rates remains challenging. Diminished ovarian reserve and premature ovarian insufficiency hinder IVF success—about 20% of in vitro fertilization (IVF) patients face a poor prognosis due to a low response, leading to higher cancellations and reduced birth rates. In an attempt to address the issue of premature ovarian insufficiency (POI), we conducted systematic PubMed and Web of Science research, using keywords “stem cells”, “extracellular vesicles”, “premature ovarian insufficiency”, “diminished ovar

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Vuong, Lan Ngoc, Tuong M. Ho, Anh N. Ha, et al. "The effect of intra-ovarian androgen priming on ovarian reserve parameters in Bologna poor responders." Reproductive BioMedicine Online 40, no. 2 (2020): 223–28. http://dx.doi.org/10.1016/j.rbmo.2019.11.005.

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Singh, Neeta, Rinchen Zangmo, Sunesh Kumar, et al. "A prospective study on role of dehydroepiandrosterone (DHEA) on improving the ovarian reserve markers in infertile patients with poor ovarian reserve." Gynecological Endocrinology 29, no. 11 (2013): 989–92. http://dx.doi.org/10.3109/09513590.2013.824957.

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Polyzos, N. P., and B. Popovic-Todorovic. "SAY NO to mild ovarian stimulation for all poor responders: it is time to realize that not all poor responders are the same." Human Reproduction 35, no. 9 (2020): 1964–71. http://dx.doi.org/10.1093/humrep/deaa183.

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ABSTRACT Over the last 25 years, a vast body of literature has been published evaluating different treatment modalities for the management of poor ovarian responders. Despite the evidence that maximizing ovarian response can improve the chances of live born babies in poor responders, there are still voices suggesting that all poor responders are the same, irrespective of their age and their actual ovarian reserve. This has resulted in the suggestion of adopting a mild ovarian stimulation approach for all poor responders, based on the results of several trials which failed to identity differenc

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Das, Subrata, Namrata Bhattacharya, Ritu Mahata, Sudip Ghosh, Anindya Sundar Bhar, and Pragati Srivastava. "Correlation of Follicle-stimulating Hormone, Anti-Mullerian Hormone, and Antral Follicle Count with Age in Ovarian Reserve Testing." International Journal of Applied & Basic Medical Research 14, no. 3 (2024): 162–68. http://dx.doi.org/10.4103/ijabmr.ijabmr_81_24.

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Abstract Objective: Ovarian reserve and hence ovarian response has a key role in assisted reproductive technology and predicting response to gonadotrophins in controlled ovarian hyperstimulation. Various tools, namely follicle-stimulating hormone (FSH), anti-Mullerian hormone (AMH), antral follicle count (AFC), estradiol, etc., have been studied to discover the best determinant of ovarian reserve. The aim of our study is to correlate different reproductive hormones with age of women to estimate ovarian reserve and to evaluate reliable marker for aiding infertility treatment. Materials and Meth

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Rai, Seema, Yasaswi Khandavalli, and Rama S. Lodha. "Is there a perfect protocol for patients with low ovarian reserve: a retrospective study comparing antagonist or agonist protocol in patients with low ovarian reserve." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 8 (2020): 3151. http://dx.doi.org/10.18203/2320-1770.ijrcog20203046.

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Background: The high prevalence of infertility has made it a major healthcare problem in the present era. A majority of patients presenting with infertility have poor ovarian reserve (POR). Patients with POR are challenging to treat due to reduced treatment success and high cycle cancellation rate as there is no uniform definition and treatment protocol for these patients. The present retrospective study was performed to compare the pregnancy outcome between a long agonist protocol and flexible antagonist protocol in patients with POR. Patients with AMH ≤1.5 ng/mL and AFC ≤4 was included in th

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Nadă, Elena-Silvia, Cătălin Bogdan Coroleucă, Ciprian Andrei Coroleucă, and Elvira Brătilă. "Ovarian Stimulation for In Vitro Fertilization and Reproductive Outcome after Surgical Treatment of Endometriosis Compared with Tubal Factor Infertility." Clinics and Practice 14, no. 1 (2023): 1–12. http://dx.doi.org/10.3390/clinpract14010001.

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Endometriosis is a common cause of infertility among reproductive-age women. A low ovarian reserve is associated with the presence of endometriotic cysts, and this is accentuated even more after surgery. Patients with a history of endometrioma are a special category of poor ovarian reserve requiring in vitro fertilization (IVF). The aim of this retrospective study was to evaluate the characteristics and outcome of ovarian stimulation and embryo transfer in women with a history of ovarian surgery for endometrioma compared with a control group with tubal factor infertility. A total of 146 patien

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Ubaldi, Filippo, Alberto Vaiarelli, Rosario D’Anna, and Laura Rienzi. "Management of Poor Responders in IVF: Is There Anything New?" BioMed Research International 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/352098.

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Despite the fact that in the last two decades an enormous number of papers on the topic of poor ovarian response have been published in the literature, so far it has been impossible to identify any efficient treatment to improve the ovarian response and the clinical outcome of this group of patients. The incidence of poor ovarian responders among infertile women has been estimated at 9–24% but according to recent reviews, it seems to have slightly increased. The limitation in quantifying the incidence of these patients among the infertile population is due to the difficulty of a clear definiti

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Voros, Charalampos, Antonia Varthaliti, Despoina Mavrogianni, et al. "Epigenetic Alterations in Ovarian Function and Their Impact on Assisted Reproductive Technologies: A Systematic Review." Biomedicines 13, no. 3 (2025): 730. https://doi.org/10.3390/biomedicines13030730.

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Background: Epigenetic modifications have an important role in controlling ovarian function, modulating ovarian response and implantation success in Assisted Reproductive Technologies (ART). The alterations, such as DNA methylation and non-coding RNA control, have been identified as key variables regulating ovarian physiology and reproductive outcomes. This systematic review investigates the significance of epigenetic pathways in ovarian function, with an emphasis on their effect on ART success rates. Methods: A thorough search of the PubMed, Scopus, and EMBASE databases was performed to find

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