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Relevant bibliographies by topics / Population modeling approaches / Dissertations / Theses

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Dissertations / Theses on the topic 'Population modeling approaches'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Awasthi, Rakesh. "Application of modeling-based approaches to study the pharmacokinetics and pharmacodynamics of Delta-9-tetrahydrocannabinol (THC) and its active metabolite." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5410.

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The medical use of marijuana is increasing, yet little is known about the exposure-response relationships resulting in its psychoactive effects. Δ9-tetrahydrocannabinol (THC) and its active metabolite (11-hydroxy-THC; THC-OH) are the principal psychoactive components in marijuana. It is well known that the plasma concentrations of the psychoactive components of marijuana do not directly relate to the observed psychoactive effects. The presence of a counter-clockwise hysteresis in the plasma concentrations-effect plot demonstrates a temporal delay between the plasma concentrations and observed

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2

Riff, Camille. "Pharmacocinétique de la ropivacaïne et de la lidocaïne au cours de la chirurgie carcinologique du sein et évaluation de la toxicité aux anesthésiques locaux en anesthésie locorégionale." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0395/document.

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Ces dernières décennies, de nouvelles techniques d’anesthésie-analgésie locorégionales ont permis d’améliorer la prise en charge post-opératoire. Cependant, les anesthésiques locaux (AL) exposent les patients à un risque de toxicité systémique potentiellement fatale. La première étude est une étude rétrospective ayant inclus des cas potentiels de toxicité systémique aux AL. Cette étude a montré que, face à l’importante variabilité pharmacocinétique des AL observée, l’interprétation des concentrations est difficile. Sa contribution au diagnostic clinique est limitée aux prélèvements précoces ap

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Bhongsatiern, Jiraganya (JJ). "Population Pharmacokinetics and Dosing Recommendations of Vancomycin in Neonates Using Modeling and Simulation Approach." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1447689427.

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Trifonova, Neda. "Machine-learning approaches for modelling fish population dynamics." Thesis, Brunel University, 2016. http://bura.brunel.ac.uk/handle/2438/13386.

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Ecosystems consist of complex dynamic interactions among species and the environment, the understanding of which has implications for predicting the environmental response to changes in climate and biodiversity. Understanding the nature of functional relationships (such as prey-predator) between species is important for building predictive models. However, modelling the interactions with external stressors over time and space is also essential for ecosystem-based approaches to fisheries management. With the recent adoption of more explorative tools, like Bayesian networks, in predictive ecolog

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Sharp, Jennifer M. "A geometric approach to modelling interacting populations." Thesis, University of Plymouth, 1997. http://hdl.handle.net/10026.1/1789.

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The purpose of this thesis is to present a different approach to the formulation of differential equation mathematical models for interacting populations. It does this through considering a geometric method. The solution to the differential equations are forced, through theuformulation, to lie on the surface of well known three-dimensional shapes. It is this that allows detailed analysis of how, and why, the solution of the equations behave as they do. The thesis firstly reviews some of the skills and techniques used in the formulation and alysis of differential equation models to give a backg

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Edwards, Andrew Michael. "A rational dynamical-systems approach to plankton population modelling." Thesis, University of Leeds, 1997. http://etheses.whiterose.ac.uk/21072/.

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Understanding the dynamics of plankton populations is of major importance since plankton form the basis of marine food webs throughout the world's oceans and play a significant role in the global carbon cycle. In this thesis we examine the dynamical behaviour of plankton models, exploring sensitivities to the number of variables explicitly modelled, to the functional forms used to describe interactions, and to the parameter values chosen. The practical difficulties involved in data collection lead to uncertainties in each of these aspects of model formulation. The first model we investigate co

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Gibiansky, Ekaterina. "Population pharmacokinetics : model-free approach and nonlinear mixed-effects modelling." Thesis, University of Greenwich, 1999. http://gala.gre.ac.uk/8654/.

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The work is devoted to the application and further development of modern statistical methods to study pharmacokinetics of drugs. Specifically, it deals with applications and development of repeated measures analysis, so called 'population approach' methods, in the field of pharmacokinetics. hi the first part of the thesis, a new, model-free approach is developed and tested. It introduces a model-free measure of patient's exposure to drugs, and then investigates the relationships between the exposure level and covariates using various statistical techniques. Classification tree models (CART) an

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Podéus, Henrik. "Neural response of a Neuron population : A mathematical modelling approach." Thesis, Linköpings universitet, Avdelningen för medicinsk teknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-177797.

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The brain – the organ that allows us to be aware of our surroundings – consists of a complex network of neurons, which seemingly allows the human brain to be able of abstract thinking, emotions, and cognitive function. To learn how the brain is capable of this, the two main branches of neuroscience study either neurons in detail, or how they communicate within neuronal networks. Both these branches often tackle the complexity using a combination of experiments and mathematical modelling. A third and less studied aspect of neuroscience concerns the neurovascular coupling (NVC), for which my res

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9

Rosario, Maria C. P. "Applications of population and other analytical approaches to pharmacokinetic and pharmacokinetic/pharmacodynamic modelling." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272881.

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10

Nothnagl, Margit. "Interaction between greenhouse grown chrysanthemum and Frankliniella occidentalis : a modelling approach /." Alnarp : Department of Crop Science, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200697.pdf.

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11

Parikh, Nidhi Kiranbhai. "Behavior Modeling and Analytics for Urban Computing: A Synthetic Information-based Approach." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/84967.

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The rapid increase in urbanization poses challenges in diverse areas such as energy, transportation, pandemic planning, and disaster response. Planning for urbanization is a big challenge because cities are complex systems consisting of human populations, infrastructures, and interactions and interdependence among them. This dissertation focuses on a synthetic information-based approach for modeling human activities and behaviors for two urban science applications, epidemiology and disaster planning, and with associated analytics. Synthetic information is a data-driven approach to create a det

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Alassadi, Abdulrahman. "An Individual-based Simulation Approach for Generating a Synthetic Stroke Population." Thesis, Malmö universitet, Malmö högskola, Institutionen för datavetenskap och medieteknik (DVMT), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-41895.

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The time to treatment plays a major factor in recovery for stroke patients, and simulation techniques can be valuable tools for testing healthcare policies and improving the situation for stroke patients. However, simulation requires individual-level data about stroke patients which cannot be acquired due to patient’s privacy rules. This thesis presents a hybrid simulation model for generating a synthetic population of stroke patients by combining Agent-based and microsimulation modeling. Subsequently, Agent-based simulation is used to estimate the locations where strokes happen. The simulatio

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13

Hershfeld, Donald Christopher. "Assessing potential navigation impacts to the Kanawha river ecosystem: a modeling approach." Thesis, Virginia Tech, 1987. http://hdl.handle.net/10919/45796.

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<p>An extensive study of the biota of the Kanawha River was integrated to examine the trophic basis of fish production and predict potential impacts of increased tow traffic at two sites in the Winfield Pool. Total standing stock and production of adult fish were estimated as 242 kg/ha and 188 kg/ha/yr, respectively. Sixtyâ one species were categorized into six trophic groups. Trophic generalists (omnivores and herbivore/detritivores) consumed a variety of foods including considerable detritus. These groups accounted for 73 to 83% of total ichthyomass and 81% of total adult production. T

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You, Benoît. "Dynamic analysis of serum tumor marker decline during anti-cancer treatment using population kinetic modeling approach." Phd thesis, Université Claude Bernard - Lyon I, 2011. http://tel.archives-ouvertes.fr/tel-00848364.

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Several cancers are associated with abnormal serum concentrations of tumor markers such as prostate specific antigen (PSA) in prostate tumor diseases, alfa-fetoprotein (AFP) or human chorionic gonadotrophin (hCG) in germ cell tumors or persistent gestational trophoblastic diseases (GTD). Cancer treatment should induce decline of serum tumor marker concentrations. The predictive values of many kinetic parameters supposed to characterize tumor marker declines such as nadir, time-point cutoff, half-life, time to normalization etc..., have been reported in previous studies. However very few of the

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Lartey, Nathaniel. "Differentials in unemployment duration across households in South Africa: A two-level modelling approach." University of the Western Cape, 2018. http://hdl.handle.net/11394/6783.

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Philosophiae Doctor - PhD<br>This study aimed to examine the structural changes affecting the duration of unemployment across households in South Africa. It made use of existing datasets from the Labour Force Survey produced by Statistics South Africa, covering a period of six years (2011-2016). Relations among demographic and household variables were explored to determine how they related to unemployment duration. On the basis of the relations identified, a predictive analysis of unemployment duration was attempted using two-level modelling. The results suggest a significant difference in the

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Smith, Gillian W. "Modelling patterns of polydrug use in the population of Great Britain : A latent class approach." Thesis, University of Ulster, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502892.

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Worrall, Eve. "An economic evaluation of malaria early warning systems in Africa : a population dynamic modelling approach." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250226.

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Barnes, Jami R. "An Integrative Approach to Conservation of the Crested Caracara (Caracara Cheriway)in Florida: Linking Demographic and Habitat Modeling for Prioritization." Bowling Green, Ohio : Bowling Green State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1182527612.

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Gabr, Hend Mohammed Kamel Mohammed. "Investigating poverty and labour force participation among older population in Egypt : a multilevel simultaneous equations modeling approach." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6551/.

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This study has investigated the relationship between elderly poverty and their labour force participation based on the Egyptian Household Observatory Survey - Round 7 dataset (IDSC, 2010). I have considered two methodological problems that plague many existent researches, endogeneity and hierarchical structure of the data. A measure of poverty in old age that captured five broad dimensions of poverty has been constructed using factor analysis technique. To investigate the main determinants of poverty and labour force participation, I have developed four single-level models and four multilevel-

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20

Wendling, Thierry. "Hierarchical mechanistic modelling of clinical pharmacokinetic data." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/hierarchical-mechanistic-modelling-of-clinical-pharmacokinetic-data(573652c9-d3fb-4233-bea7-7abd7ef48d4b).html.

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Pharmacokinetic and pharmacodynamic models can be applied to clinical study data using various modelling approaches depending on the aim of the analysis. In population pharmacokinetics for instance, simple compartmental models can be employed to describe concentration-time data, identify prognostic factors and interpolate within well-defined experimental conditions. The first objective of this thesis was to illustrate such a ‘semi-mechanistic’ pharmacokinetic modelling approach using mavoglurant as an example of a compound under clinical development. In particular, methods to accurately charac

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Tiret, Mathieu. "Approche multilocus du génome dans les modèles de génétique des populations." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLA002/document.

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La génétique des populations est l’étude de l’évolution des fréquences alléliques au sein d’une population et de l’influence des pressions évolutives sur ces fréquences. Au sein de cette discipline, des modèles de population et des mesures génétiques sont développés pour pouvoir expliquer et prédire les données génétiques. Toutefois, au fur et à mesure des avancées technologiques, de nouveaux types de données sont disponibles, et il devient primordial de développer de nouveaux modèles et de nouvelles mesures pour pouvoir expliquer ces nouvelles données génétiques, plus denses et plus riches en

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22

Zurell, Damaris. "Integrating dynamic and statistical modelling approaches in order to improve predictions for scenarios of environmental change." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5684/.

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Species respond to environmental change by dynamically adjusting their geographical ranges. Robust predictions of these changes are prerequisites to inform dynamic and sustainable conservation strategies. Correlative species distribution models (SDMs) relate species’ occurrence records to prevailing environmental factors to describe the environmental niche. They have been widely applied in global change context as they have comparably low data requirements and allow for rapid assessments of potential future species’ distributions. However, due to their static nature, transient responses to env

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Walker, Neil J. "The analysis of epidemiological data on bovine tuberculosis in a wild badger population : an investigation of approaches to statistical modelling." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633250.

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Bovine tuberculosis is a chronic disease common to a wide range of mammalian specie~ caused by infection with the bacteria Mycobacterium bovis. Eurasian Badgers Meles meles are implicated in the spread of bovine tuberculosis to domestic cattle in the United Kingdom. A long-term study into the epidemiology of bovine tuberculosis in a wild badger population at Woodchester Park in Gloucestershire, England, has been ongoing since 1975. This has given rise to a dataset of more than 15000 observations to date consisting of various de: mographic and biological data on resident badgers in addition to

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Wood, David. "Forest Disturbance and the Long Term Population Persistence of the Mt. Graham Red Squirrel: A Spatially Explicit Modeling Approach." Thesis, The University of Arizona, 2007. http://hdl.handle.net/10150/193362.

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We combined field data with high-resolution satellite imagery and a spatially explicit population model to predict long-term population dynamics of the endangered Mt. Graham red squirrel (MGRS: Tamiasciurus hudsonicus grahamensis), with the goal of examining effects of disturbance on MGRS population dynamics. We found that modeling MGRS dynamics improved with population specific data. Our results indicate that predation and competition potentially have large, adverse effects on population abundance. Habitat quality analysis indicates much of the spruce-fir forest is degraded to the point th

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Udono, Ken, and n/a. "Modelling Seawater Desalination With Waste Incineration Energy Using Dynamic Systems Approach." Griffith University. School of Information and Communication Technology, 2006. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20070110.164750.

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Water shortage issues have been growing concerns in many cities around the world in recent years, especially in Eastern cities of Australia, which is the driest continent on the earth. The aim of this PhD thesis is a development of a model to study the use of waste incineration energy supplemented by alternative energy to power seawater desalination. It is to aid the freshwater supply of a drought stricken city in Eastern Australia. My work contributes to a development of efficient model in a simpler understandable way to reduce efforts required for modelling complex multi domain problems. Thi

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Botha, Jakobus Stephanus. "Modelling dominance shifts of anchovy and sardine with a frame-based approach : sensitivity to the underlying sardine population dynamics." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/10261.

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Includes bibliographical references.<br>It has been shown that sardine and anchovy populations in the southern Benguela have alternated dominance during the past 50 years, and a frame based model that explores the usefulness of frames within a marine ecosystem by modelling sardine/anchovy dominance shifts in the southern Benguela has been developed in a previous study. The existing model contains a sardine population sub-model without age structure and the inclusion of age-structure allows age-related dynamics to be incorporated in the model design. In this mini-dissertation, an age-structured

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27

Staley, Jeremy Ross. "Aspects of the population dynamics of Lochmaea suturalis Thompson (Coleoptera: Chrysomelidae; sub-family: Galerucinae), the heather beetle : a combined laboratory and modelling approach." Thesis, University of Newcastle Upon Tyne, 2000. http://hdl.handle.net/10443/956.

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This thesis describes a series of laboratory and field experiments that quantify the population dynamics of the heather beetle (Lochmaea suturalis Thomson), in relation to temperature and its host plant heather (Calluna vulgaris (L. ) Hull). The sex ratio, fecundity, egg laying threshold temperature, emergence threshold temperature, life stage development periods, and life stage mortalities were investigated. It was shown that the life stages were significantly dependent on temperature, whilst it was shown that there was no significant relationship between larval growth and Calluna vulgaris pl

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Inoue, Kentaro. "A Comprehensive Approach to Conservation Biology: From Population Genetics to Extinction Risk Assessment for Two Species of Freshwater Mussels." Miami University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=miami1437683696.

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Suvarnaraksha, Apinun. "Biology of two keystone fish species and fish assemblage patterns and modeling approaches in tropical river basin : case study of Ping river basin, Thailand." Toulouse 3, 2011. http://thesesups.ups-tlse.fr/1537/.

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La région Indo-Birmane est un formidable hotspot de diversité biologique, mais il existe un manque évident de connaissances fiables sur la diversité des poissons, la biologie et l'histoire de vie des communautés, ainsi que des approches de modélisation des données. Ce travail de thèse apporte des informations sur la diversité des poissons et de la distribution dans une zone de montagne de haute et de basse altitude dans la partie supérieure du bassin du fleuve Chao Phraya, en Thaïlande. Des données de terrain ont été collectées sur quatorze années entre Janvier 1996 et avril 2009, couvrant 272

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Christal, Anna. "Intraspecific variation in seed dormancy and germination among populations of Stellaria media and Galium aparine : a modelling approach to investigate the effects of environmental and management factors." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/27792.

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This thesis aims to describe aspects of the ecology of two common winter annual weed species, <i>Stellaria media</i> and <i>Galium aparine</i>, in order to support the development of more sustainable weed control measures in arable crops. In arable crops, effective broad-leaved weed control tends to be associated with the early removal of weed seedlings and this may be facilitated by predictions of the timing and extent of weed seedling emergence. Seedling emergence can be divided into three stages: seed dormancy, seed germination and seedling pre-emergence growth. Seed dormancy and germinatio

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Cave, Vanessa M. "Statistical models for the long-term monitoring of songbird populations : a Bayesian analysis of constant effort sites and ring-recovery data." Thesis, St Andrews, 2010. http://hdl.handle.net/10023/885.

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Chu, Yue. "SVD-BAYES: A SINGULAR VALUE DECOMPOSITION-BASED APPROACH UNDER BAYESIAN FRAMEWORK FOR INDIRECT ESTIMATION OF AGE-SPECIFIC FERTILITY AND MORTALITY." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1609638415015896.

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Leding, Albin. "Optimized design recommendation for first pharmacokinetic in vivo experiments for new tuberculosis drugs using pharmacometrics modelling and simulation." Thesis, Uppsala universitet, Institutionen för farmaci, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447311.

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Tuberculosis, the leading cause of death by a single infection disease caused by bacteria, requires long treatments and the bacteria are prone to develop drug resistance. Therefore, new efficient treatment regiments needs developing, which requires new tools for drug development. A major reason for discontinuance of a drug under development is undesired pharmacokinetic properties. Therefore, it is important to have early information of this, preferably the first time the drug is tested in animals. The first in vivo pharmacokinetic experiment is often done in mice and the only information prese

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Sanchis, Cano Ángel. "Economic analysis of wireless sensor-based services in the framework of the Internet of Things. A game-theoretical approach." Doctoral thesis, Universitat Politècnica de València, 2018. http://hdl.handle.net/10251/102642.

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El mundo de las telecomunicaciones está cambiando de un escenario donde únicamente las personas estaban conectadas a un modelo donde prácticamente todos los dispositivos y sensores se encuentran conectados, también conocido como Internet de las cosas (IoT), donde miles de millones de dispositivos se conectarán a Internet a través de conexiones móviles y redes fijas. En este contexto, hay muchos retos que superar, desde el desarrollo de nuevos estándares de comunicación al estudio de la viabilidad económica de los posibles escenarios futuros. En esta tesis nos hemos centrado en el estudio de la

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Jagadesh, Soushieta. "Biogeography of Emerging Infectious Diseases In search for the hotspots of Disease X: A biogeographic approach to mapping the predictive risk of WHO’s Blueprint Priority Diseases Emerging human infectious diseases of aquatic origin: a comparative biogeographic approach using Bayesian spatial modelling Global emergence of Buruli Ulcer Spatial variations between Leishmania species: A biogeographic approach to mapping the distribution of Leishmania species in French Guiana Mapping priority neighborhoods: A novel approach to cluster identification in HIV/AIDS population." Thesis, Guyane, 2020. http://www.theses.fr/2020YANE0007.

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La récente pandémie de Covid19 nous rappelle, si cela était encore nécessaire, que la propagation des maladies infectieuses ignore les frontières géographiques. Les changements combinés de biodiversité locale et l’utilisation des terres, l’augmentation de la connectivité internationale par le transport et le commerce ainsi que la menace imminente du changement climatique a accru le risque d’émergence et de réémergence des maladies infectieuses (EMI). Jusqu’à présent la réponse des politiques de santé publique a été la surveillance passive sans toutefois s’avérer réellement efficace dans la pré

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Khomarudin, Muhammad Rokhis [Verfasser]. "Tsunami risk and vulnerability : remote sensing and GIS approaches for surface roughness determination, settlement mapping and population distribution modeling / eingereicht Muhammad Rokhis Khomarudin." 2010. http://d-nb.info/1009607820/34.

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"Populations, farming systems and social transitions in Sahelian Niger : an agent-based modeling approach." Université catholique de Louvain, 2008. http://edoc.bib.ucl.ac.be:81/ETD-db/collection/available/BelnUcetd-06152008-182729/.

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Stretch, Anne-Marie. "A modelling approach to elephant and tree population dynamics for a small game farm." Thesis, 2005. http://hdl.handle.net/10321/110.

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Thesis (M.Tech.: Information Technology)-Durban Institute of Technology, 2005 iii, iii, 85 leaves<br>Throughout Africa, growing human populations and resulting loss of wildlife habitat is a critical issue for most animal species. It is more and more common for privately owned small or medium sized farms to reintroduce wildlife on their land and such protected areas are fast becoming the only refuges available to wild animals. However a comprehensive understanding of the complex ecological processes taking place is vital for the effective management of restricted areas and the conservation

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Bastos, Rita Coelho. "Foraging ecology of breeding shearwaters in the North Atlantic: A multi-level modelling approach to support upcoming decision-making for the conservation of marine ecosystems." Doctoral thesis, 2021. http://hdl.handle.net/10348/10493.

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Tese de Doutoramento em Ciência, Tecnologia e Gestão do Mar<br>Global warming is forcing persistent and unprecedented changes in the marine environment, imposing a major challenge to scientists, policy makers and environmental managers in finding solutions for the oceans future sustainability. Marine top predators, such as seabirds, are largely regulated by food web dynamics, offering unique insights into marine ecosystem status and change. Therefore, predicting seabird responses to variations in resources availability and anticipating their ability to cope with future environmental conditions

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Hatzopoulou, Marianne. "An Integrated Multi-model Approach for Predicting the Impact of Household Travel on Urban Air Quality and Simulating Population Exposure." Thesis, 2008. http://hdl.handle.net/1807/16731.

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The population and economic growth experienced by Canadian metropolitan areas in the past twenty years, has been associated with increased levels of car ownership and vehicle kilometres travelled leading to a deterioration of air quality and public health and an increase in greenhouse gas emissions. The need to modify urban growth patterns has motivated planning agencies in Canada to develop a broad range of policies aiming at achieving a more sustainable transportation sector. The challenge however, remains in the ability to test the effectiveness of proposed policy measures. This situation h

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Lin, Ching-Yu, and 林勁宇. "Analyzing Associations of Chronic Risk Factors With Dementia in a Population-Based Cohort of Stroke Cases – a Semi-Markov Modeling Approach." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/86y4td.

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碩士<br>國立臺灣科技大學<br>工業管理系<br>105<br>This study employed a multistate semi-Markov model and the cox proportional method to analysis associations of various chronic risk factors with the dementia. We included 10,627 patients of stroke diagnosed between 2000 and 2010 who were recruited in National Health Insurance Research Database (NHIRD) for a population-based study, and retrospectively followed up until the end of 2010. Chronic, hemorrhagic stroke and ischemic stroke were included as intermediate states, and vascular dementia and non-vascular dementia were included as competing absorbing states.

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Bauer, Silke [Verfasser]. "Modelling competition with the field-of-neighbourhood approach : from individual interactions to population dynamics of plants / vorgelegt von Silke Bauer." 2003. http://d-nb.info/972758828/34.

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Suleman, Nazira. "Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals." Master's thesis, 2018. http://hdl.handle.net/10451/40032.

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Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2018<br>A farmacoeconomia é uma disciplina que avalia o uso de medicamentos em termos de recursos na maximização da saúde da população. Dado que os recursos para os cuidados de saúde são finitos, a avaliação económica envolve a estimativa do custo de oportunidade, i.e., os benefícios marginais perdidos como resultado do deslocamento de tratamentos ou serviços existentes para financiar novos medicamentos. A farmacocinética é a ciência que visa o estudo do movimento de fármacos no organismo, o que inclui

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