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Journal articles on the topic 'Porous biomaterials'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Bonini, Fabien, Sébastien Mosser, Flavio Maurizio Mor, et al. "The Role of Interstitial Fluid Pressure in Cerebral Porous Biomaterial Integration." Brain Sciences 12, no. 4 (2022): 417. http://dx.doi.org/10.3390/brainsci12040417.

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Recent advances in biomaterials offer new possibilities for brain tissue reconstruction. Biocompatibility, provision of cell adhesion motives and mechanical properties are among the present main design criteria. We here propose a radically new and potentially major element determining biointegration of porous biomaterials: the favorable effect of interstitial fluid pressure (IFP). The force applied by the lymphatic system through the interstitial fluid pressure on biomaterial integration has mostly been neglected so far. We hypothesize it has the potential to force 3D biointegration of porous

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2

Bonfield, William. "Designing porous scaffolds for tissue engineering." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 364, no. 1838 (2005): 227–32. http://dx.doi.org/10.1098/rsta.2005.1692.

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Biomaterials are either modified natural or synthetic materials, with an appropriate response in the host tissue, which find application in a wide spectrum of implants and prostheses used in reconstructive medicine. The subsequent integration and longevity of the implanted device depends on the effectiveness of the associated biological repair. Hence, there has been considerable interest in the development of novel, second generation, biomaterials, which are favourably bioactive in terms of promoting the desired cellular response in vivo . Such biomaterials in a porous form can also act as cel

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Okulov, I. V., A. V. Okulov, I. V. Soldatov, et al. "Open porous dealloying-based biomaterials as a novel biomaterial platform." Materials Science and Engineering: C 88 (July 2018): 95–103. http://dx.doi.org/10.1016/j.msec.2018.03.008.

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4

Chen, Chang Jun, and Min Zhang. "Fabrication Methods of Porous Tantalum Metal Implants for Use as Biomaterials." Advanced Materials Research 476-478 (February 2012): 2063–66. http://dx.doi.org/10.4028/www.scientific.net/amr.476-478.2063.

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Porous tantalum; biomaterials; bone ingrowth; laser cladding; Abstract. Porous tantalum, a new low modulus metal with a characteristic appearance similar to cancellous/trabecular bone, is currently available for use in several orthopedic applications (hip and knee arthroplasty, spine surgery, and bone graft substitute). The open-cell structure of repeating dodecahedrons is produced via carbon vapor deposition/infiltration of commercially pure tantalum onto a vitreous carbon scaffolding. This transition metal maintains several interesting biomaterial properties, including: a high volumetric por

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5

Septiadi, Wayan Nata, and Nandy Putra. "Boiling Phenomenon of Tabulate Biomaterial Wick Heat Pipe." Applied Mechanics and Materials 776 (July 2015): 289–93. http://dx.doi.org/10.4028/www.scientific.net/amm.776.289.

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This research purposed to know the performance of heat pipe using wick made from biomaterial. Biomaterial (Coral) is the porous media which has the relative homogenous and small porous structures. The homogenous structures and the small biomaterial have the better capillarity and could be used as wick to circulate condensate in heat pipe. The heat pipe made from copper pipe with 50 mm in length and the inside and outer diameter was 25 mm and 24 mm in each, with the wick as thick as 1 mm made from Tabulate. Heat sink was adhered to the condenser part of heat pipe as wide as 637.5 cm2. The study

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6

Miao, Xigeng, and Dan Sun. "Graded/Gradient Porous Biomaterials." Materials 3, no. 1 (2009): 26–47. http://dx.doi.org/10.3390/ma3010026.

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7

Peng, Zhiyu, Pei Tang, Li Zhao, et al. "Advances in biomaterials for adipose tissue reconstruction in plastic surgery." Nanotechnology Reviews 9, no. 1 (2020): 385–95. http://dx.doi.org/10.1515/ntrev-2020-0028.

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AbstractAdipose tissue reconstruction is an important technique for soft tissue defects caused by facial plastic surgery and trauma. Adipose tissue reconstruction can be repaired by fat transplantation and biomaterial filling, but there are some problems in fat transplantation, such as second operation and limited resources. The application of advanced artificial biomaterials is a promising strategy. In this paper, injectable biomaterials and three-dimensional (3D) tissue-engineered scaffold materials for adipose tissue reconstruction in plastic surgery are reviewed. Injectable biomaterials in

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8

Zadpoor, Amir A. "Additively manufactured porous metallic biomaterials." Journal of Materials Chemistry B 7, no. 26 (2019): 4088–117. http://dx.doi.org/10.1039/c9tb00420c.

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Additively manufactured (AM, =3D printed) porous metallic biomaterials with topologically ordered unit cells have created a lot of excitement and are currently receiving a lot of attention given their great potential for improving bone tissue regeneration and preventing implant-associated infections.

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9

Ayers, Reed A., Douglas E. Burkes, Guglielmo Gottoli, et al. "Combustion synthesis of porous biomaterials." Journal of Biomedical Materials Research Part A 81A, no. 3 (2007): 634–43. http://dx.doi.org/10.1002/jbm.a.31017.

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10

Kim, Hyeon Joo, Hyun Suk Kim, Akira Matsumoto, In-Joo Chin, Hyoung-Joon Jin, and David L. Kaplan. "Processing Windows for Forming Silk Fibroin Biomaterials into a 3D Porous Matrix." Australian Journal of Chemistry 58, no. 10 (2005): 716. http://dx.doi.org/10.1071/ch05170.

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In the present study we clarify phase diagrams related to silk fibroin processing into three-dimensional porous structures useful for biomaterials and for scaffolds in tissue engineering. All-aqueous and organic solvent (hexafluoroisopropanol) modes of processing are compared relative to solution concentration of silk protein polymer and size of porogen (NaCl particles). The results clarify the range of conditions under which these biomaterial matrices can be formed, with a broader range of pore sizes and smoother surface morphology generated from the organic solvent process. These structures

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11

Chen, Ji Yong, You Rong Duan, and Xing Dong Zhang. "Effect of Microstructure on Osteoinductivity of Biomaterials." Key Engineering Materials 284-286 (April 2005): 289–92. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.289.

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Two sets of porous biphasic calcium phosphate ceramics (BCP) were prepared for dynamic SBF experiment: porous BCP with micropores on the walls of macropores( set A) and porous BCP with dense walls of macropores (set B). Apatite layer could only formed on the macropore walls with micropores. Four groups of specimens were prepared for animal experiments. Group A was porous BCP ceramics with micropores on the walls of macropores; group B was porous BCP with dense walls of macropores; group C was porous BCP ceramics with apatite layers formed by static SBF[2]on their surfaces; group D was porous B

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12

Pinheiro, Juliana Campos, Braz da Fonseca Neto, Jabes Gennedyr da Cruz Lima, et al. "Use of biomaterials in the surgical regenerative treatment of peri-implantitis: systematic review." Research, Society and Development 10, no. 12 (2021): e275101220454. http://dx.doi.org/10.33448/rsd-v10i12.20454.

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The aim of this study was to review the scientific literature regarding the effectiveness of different biomaterials in the regenerative treatment of peri-implantitis. A systematic literature search was performed in PubMed/Medline, Web of Science, Science Direct, Embase, and the Cochrane Collaboration Library. Studies on the use of biomaterials in the regenerative treatment of peri-implantitis were selected. The search strategy retrieved 253 articles. After selection, six articles met all inclusion criteria and were included in the present systematic review. The studies showed that an initial t

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13

Ansari, Mojtaba. "Bone tissue regeneration: biology, strategies and interface studies." Progress in Biomaterials 8, no. 4 (2019): 223–37. http://dx.doi.org/10.1007/s40204-019-00125-z.

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AbstractNowadays, bone diseases and defects as a result of trauma, cancers, infections and degenerative and inflammatory conditions are increasing. Consequently, bone repair and replacement have been developed with improvement of orthopedic technologies and biomaterials of superior properties. This review paper is intended to sum up and discuss the most relevant studies performed in the field of bone biology and bone regeneration approaches. Therefore, the bone tissue regeneration was investigated by synthetic substitutes, scaffolds incorporating active molecules, nanomedicine, cell-based prod

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14

Lin, Qiukai, Yingzhe Cheng, and Dexing Chen. "Synthesis of hierarchically porous carbon doped with molybdate for capturing the greenhouse gas SF₆." Journal of Physics: Conference Series 3009, no. 1 (2025): 012062. https://doi.org/10.1088/1742-6596/3009/1/012062.

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Abstract Biomass carbon materials are economical and effective for preparing gas adsorbents. In this study, tung nut shells were pyrolyzed to create three types of porous structural carbonized biomass doped with molybdate for capturing SF6. The material prepared at 800°C (BioM8) possessed abundant micropore structures that were close to sulfur hexafluoride’s kinetic diameter. BioM8 exhibited the highest SF6 adsorption capacity (44.36 cm3/g at 0.1 bar and 298 K in ambient conditions). Multiple analysis techniques revealed that the biomaterial co-doped with molybdate improved porosity formation

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15

Prakasam, Mythili, Jean-François Silvain, and Alain Largeteau. "Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review." Bioengineering 8, no. 11 (2021): 170. http://dx.doi.org/10.3390/bioengineering8110170.

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Biomaterials and their clinical application have become well known in recent years and progress in their manufacturing processes are essential steps in their technological advancement. Great advances have been made in the field of biomaterials, including ceramics, glasses, polymers, composites, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. One of the common impediments in the bioceramics an

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16

Nurzynska, Aleksandra, Katarzyna Klimek, Iga Swierzycka, Krzysztof Palka, and Grazyna Ginalska. "Porous Curdlan-Based Hydrogels Modified with Copper Ions as Potential Dressings for Prevention and Management of Bacterial Wound Infection—An In Vitro Assessment." Polymers 12, no. 9 (2020): 1893. http://dx.doi.org/10.3390/polym12091893.

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Bacterial infections at the wound site still remain a huge problem for current medicine, as they may lead to development of chronic wounds. In order to prevent such infections, there is a need to use wound dressings that possess ability to inhibit bacterial colonization. In this study, three new curdlan-based biomaterials modified with copper ions were fabricated via simple and inexpensive procedure, and their structural, physicochemical, and biological properties in vitro were evaluated. Received biomaterials possessed porous structure, had ability to absorb high amount of simulated wound flu

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17

Amalakanti, Sridhar, Rajendra Prasad Mulpuri, and Vijaya Chandra Reddy Avula. "Recent advances in biomaterial design for nerve guidance conduits: a narrative review." Advanced Technology in Neuroscience 1, no. 1 (2024): 32–42. http://dx.doi.org/10.4103/atn.atn-d-23-00005.

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Researchers have made significant strides in developing biomaterials for nerve guiding conduits, exploring natural polymers like chitosan, collagen, and silk, along with synthetic counterparts such as silicone, poly(lactic-co-glycolic acid), polycaprolactone, and poly(L-lactic acid). Each material offers distinct benefits, necessitating further study for refinement. Diverse conduit designs, including hollow/non-porous, porous, grooved, multi-channel, and fiber/hydrogel-filled conduits, have been created. Multi-channel and aligned fiber designs stand out for providing effective topographical cu

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18

Zalewska, Justyna, Vladyslav Vivcharenko, and Anna Belcarz. "Gypsum-Related Impact on Antibiotic-Loaded Composite Based on Highly Porous Hydroxyapatite—Advantages and Disadvantages." International Journal of Molecular Sciences 24, no. 24 (2023): 17178. http://dx.doi.org/10.3390/ijms242417178.

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Highly porous hydroxyapatite is sometimes considered toxic and useless as a biomaterial for bone tissue regeneration because of the high adsorption of calcium and phosphate ions from cell culture media. This negatively affects the osteoblast’s growth in such ion-deprived media and suggests “false cytotoxicity” of tested hydroxyapatite. In our recent study, we showed that a small addition of calcium sulfate dihydrate (CSD) may compensate for this adsorption without a negative effect on other properties of hydroxyapatite-based biomaterials. This study was designed to verify whether such CSD-supp

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19

Prakasam, Mythili, Ali Chirazi, Grzegorz Pyka, Anna Prokhodtseva, Daniel Lichau, and Alain Largeteau. "Fabrication and Multiscale Structural Properties of Interconnected Porous Biomaterial for Tissue Engineering by Freeze Isostatic Pressure (FIP)." Journal of Functional Biomaterials 9, no. 3 (2018): 51. http://dx.doi.org/10.3390/jfb9030051.

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Biomaterial for tissue engineering is a topic of huge progress with a recent surge in fabrication and characterization advances. Biomaterials for tissue engineering applications or as scaffolds depend on various parameters such as fabrication technology, porosity, pore size, mechanical strength, and surface available for cell attachment. To serve the function of the scaffold, the porous biomaterial should have enough mechanical strength to aid in tissue engineering. With a new manufacturing technology, we have obtained high strength materials by optimizing a few processing parameters such as p

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20

Vacanti, Charles A. "The Impact of Biomaterials Research on Tissue Engineering." MRS Bulletin 26, no. 10 (2001): 798–99. http://dx.doi.org/10.1557/mrs2001.207.

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The three most important components of tissue engineering are biomaterials, cellular biology, and vascular supply. Biomaterials are needed to control the delivery of new cells into the body. In the absence of biomaterials, cells that are injected into a vein, a cavity, or tissue tend to disperse, so a sufficiently high density of cells to perform the intended function—replacement or repair of a damaged structure—is never achieved.1 A porous delivery system is needed that confines the cells to the desired location and promotes their nourishment until blood vessels grow in and new tissue is form

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21

Bai, Yunpeng, Takahiro Kanno, Hiroto Tatsumi, et al. "Feasibility of a Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/poly-d/l-lactide Composite as a Regenerative Biomaterial in Maxillofacial Surgery." Materials 11, no. 10 (2018): 2047. http://dx.doi.org/10.3390/ma11102047.

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This study evaluated the feasibility of a novel three-dimensional (3D) porous composite of uncalcined and unsintered hydroxyapatite (u-HA) and poly-d/l-lactide (PDLLA) (3D-HA/PDLLA) for the bony regenerative biomaterial in maxillofacial surgery, focusing on cellular activities and osteoconductivity properties in vitro and in vivo. In the in vitro study, we assessed the proliferation and ingrowth of preosteoblastic cells (MC3T3-E1 cells) in 3D-HA/PDLLA biomaterials using 3D cell culture, and the results indicated enhanced bioactive proliferation. After osteogenic differentiation of those cells

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22

Popescu, Ileana Nicoleta, Aurora Anca Poinescu, Dan Nicolae Ungureanu, and Adrian Picu. "Novel Developments in Advanced Materials Fields: Porous and Non-Porous Biomaterials Used in Regenerative Medicine and Tissue Engineering." Scientific Bulletin of Valahia University - Materials and Mechanics 19, no. 20 (2023): 42–52. http://dx.doi.org/10.2478/bsmm-2023-0007.

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Abstract In this brief review, porous and non-porous biomaterials used as scaffolds in regenerative medicine and tissue engineering and new innovative techniques to obtain biomaterials were discussed. Various methods have been presented to obtain advanced materials used as scaffolds, such as (i) 3D printed biomineral composites obtained with bacteria-loaded ink (bactoInk), (ii) the use of vegetable waste, such as rice husks, parsley, spinach or cocoa in the development of bioplastics, (iii) the use of natural biological materials of animal origin (such as bovine bones, corals, snail shells or

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23

Turco, Gianluca, Davide Porrelli, Eleonora Marsich, et al. "Three-Dimensional Bone Substitutes for Oral and Maxillofacial Surgery: Biological and Structural Characterization." Journal of Functional Biomaterials 9, no. 4 (2018): 62. http://dx.doi.org/10.3390/jfb9040062.

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Background: Bone substitutes, either from human (autografts and allografts) or animal (xenografts) sources, suffer from inherent drawbacks including limited availability or potential infectivity to name a few. In the last decade, synthetic biomaterials have emerged as a valid alternative for biomedical applications in the field of orthopedic and maxillofacial surgery. In particular, phosphate-based bone substitution materials have exhibited a high biocompatibility due to their chemical similitude with natural hydroxyapatite. Besides the nature of the biomaterial, its porous and interconnected

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24

Tsai, Sung Pei, Chien Yang Hsieh, Chung Yu Hsieh, Yaw Nan Chang, Da Ming Wang, and Hsyue Jen Hsieh. "Gamma-Poly(glutamic acid)/Chitosan Composite Scaffolds for Tissue Engineering Applications." Materials Science Forum 539-543 (March 2007): 567–72. http://dx.doi.org/10.4028/www.scientific.net/msf.539-543.567.

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The development of tissue engineering provides a novel approach to restore bodily functions by seeding cells onto various scaffolds. Although chitosan is a non-toxic biomaterial, its cytocompatibility still needs to be improved. In this study, gamma-poly(glutamic acid) (γ-PGA) was blended with chitosan to prepare both dense and porous γ-PGA/chitosan composite scaffolds using the freeze-gelation method. This method saves time and energy, and there is less residual solvent. SEM micrographs demonstrated that an interconnected porous structure with a pore size of 30-100 micrometer was present in t

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Dejaco, Alexander, Vladimir S. Komlev, Jakub Jaroszewicz, Wojciech Swieszkowski, and Christian Hellmich. "Fracture safety of double-porous hydroxyapatite biomaterials." Bioinspired, Biomimetic and Nanobiomaterials 5, no. 1 (2016): 24–36. http://dx.doi.org/10.1680/jbibn.15.00021.

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26

weerts, A. H., G. lian, and D. martin. "Modeling Rehydration of Porous Biomaterials: Anisotropy Effects." Journal of Food Science 68, no. 3 (2003): 937–42. http://dx.doi.org/10.1111/j.1365-2621.2003.tb08268.x.

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27

Kapfer, Sebastian, Susan Sporer, Stephen T. Hyde, Klaus Mecke, and Gerd E. Schroeder-Turk. "Elastic and Morphological Properties of Porous Biomaterials." Biophysical Journal 98, no. 3 (2010): 571a. http://dx.doi.org/10.1016/j.bpj.2009.12.3103.

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28

Kim, Yeon-wook. "Mechanical properties of highly porous Ti49.5Ni50.5 biomaterials." Intermetallics 62 (July 2015): 56–59. http://dx.doi.org/10.1016/j.intermet.2015.03.011.

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29

Stmmilto, C. Z., I. Zbicinski, and X. D. Liu. "Thermal Drying of Biomaterials with Porous Carriers." Drying Technology 13, no. 5-7 (1995): 1447–62. http://dx.doi.org/10.1080/07373939508917032.

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30

Marshall, A. J., and B. D. Ratner. "Quantitative characterization of sphere-templated porous biomaterials." AIChE Journal 51, no. 4 (2005): 1221–32. http://dx.doi.org/10.1002/aic.10390.

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31

Koolen, Marianne, Saber Amin Yavari, Karel Lietaert, Ruben Wauthle, Amir A. Zadpoor, and Harrie Weinans. "Bone Regeneration in Critical-Sized Bone Defects Treated with Additively Manufactured Porous Metallic Biomaterials: The Effects of Inelastic Mechanical Properties." Materials 13, no. 8 (2020): 1992. http://dx.doi.org/10.3390/ma13081992.

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Additively manufactured (AM) porous metallic biomaterials, in general, and AM porous titanium, in particular, have recently emerged as promising candidates for bone substitution. The porous design of such materials allows for mimicking the elastic mechanical properties of native bone tissue and showed to be effective in improving bone regeneration. It is, however, not clear what role the other mechanical properties of the bulk material such as ductility play in the performance of such biomaterials. In this study, we compared the bone tissue regeneration performance of AM porous biomaterials ma

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32

Nan, Nan, Wanhe Hu, and Jingxin Wang. "Lignin-Based Porous Biomaterials for Medical and Pharmaceutical Applications." Biomedicines 10, no. 4 (2022): 747. http://dx.doi.org/10.3390/biomedicines10040747.

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Over the past decade, lignin-based porous biomaterials have been found to have strong potential applications in the areas of drug delivery, tissue engineering, wound dressing, pharmaceutical excipients, biosensors, and medical devices. Lignin-based porous biomaterials have the addition of lignin obtained from lignocellulosic biomass. Lignin as an aromatic compound is likely to modify the materials’ mechanical properties, thermal properties, antioxidant, antibacterial property, biodegradability, and biocompatibility. The size, shape, and distribution of pores can determine the materials’ porous

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Bhat, Sumrita, and Ashok Kumar. "Biomaterials in Regenerative Medicine." Journal of Postgraduate Medicine, Education and Research 46, no. 2 (2012): 81–89. http://dx.doi.org/10.5005/jp-journals-10028-1018.

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ABSTRACT Limitations with the conventional methods have bought biomaterials to the forefront for the repair and restoration of tissue functions. Recent advances in the area of biomaterials have revolutionized the field of tissue engineering and regenerative medicine. According to the nature of polymers they are divided into different classes and each one has found applicability in the area of regenerative medicine. Each class of biomaterials has a set of properties which makes them appropriate for a specific application. The most important property is the behavior of biomaterials when implante

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Fassina, Lorenzo, Enrica Saino, Maria Gabriella Cusella De Angelis, Giovanni Magenes, Francesco Benazzo, and Livia Visai. "Low-Power Ultrasounds as a Tool to Culture Human Osteoblasts inside Cancellous Hydroxyapatite." Bioinorganic Chemistry and Applications 2010 (2010): 1–8. http://dx.doi.org/10.1155/2010/456240.

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Bone graft substitutes and cancellous biomaterials have been widely used to heal critical-size long bone defects due to trauma, tumor resection, and tissue degeneration. In particular, porous hydroxyapatite is widely used in reconstructive bone surgery owing to its biocompatibility. In addition, the in vitro modification of cancellous hydroxyapatite with osteogenic signals enhances the tissue regeneration in vivo, suggesting that the biomaterial modification could play an important role in tissue engineering. In this study, we have followed a tissue-engineering strategy where ultrasonically st

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35

Meng, Zeng-Dong, Cheng-Jian Wang, Yu-Qin Zhang, Chong Luo, Ze-Yu Wang, and Wei-Chao Li. "Porous Hydroxyapatite/Strontium Oxide Composite Ceramic Preparation and Properties of Biomaterials." Journal of Biomaterials and Tissue Engineering 9, no. 6 (2019): 783–88. http://dx.doi.org/10.1166/jbt.2019.2056.

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Objective: This study aims to added strontium to hydroxyapatite (HA) through physical means and prepare porous composite ceramic materials with good mechanical properties to further improve the osteogenesis-inducing effect of bone repairing materials. Methods: The composite powders of strontium oxide/hydroxyapatite (SrO/HA) was obtained by mechanical milling. Then, porous SrO/HA composite ceramics were prepared by spark plasma sintering. The composition, structure and morphology of these porous composite ceramic materials were characterized using X-ray diffraction and scanning electron microsc

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Klost, Martina, Claudia Keil, and Pavel Gurikov. "Dried Porous Biomaterials from Mealworm Protein Gels: Proof of Concept and Impact of Drying Method on Structural Properties and Zinc Retention." Gels 10, no. 4 (2024): 275. http://dx.doi.org/10.3390/gels10040275.

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Dried porous materials can be found in a wide range of applications. So far, they are mostly prepared from inorganic or indigestible raw materials. The aim of the presented study was to provide a proof of concept for (a) the suitability of mealworm protein gels to be turned into dried porous biomaterials by either a combination of solvent exchange and supercritical drying to obtain aerogels or by lyophilization to obtain lyophilized hydrogels and (b) the suitability of either drying method to retain trace elements such as zinc in the gels throughout the drying process. Hydrogels were prepared

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Dec, Paweł, Andrzej Modrzejewski, and Andrzej Pawlik. "Existing and Novel Biomaterials for Bone Tissue Engineering." International Journal of Molecular Sciences 24, no. 1 (2022): 529. http://dx.doi.org/10.3390/ijms24010529.

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The treatment of bone defects remains one of the major challenges in modern clinical practice. Nowadays, with the increased incidence of bone disease in an aging population, the demand for materials to repair bone defects continues to grow. Recent advances in the development of biomaterials offer new possibilities for exploring modern bone tissue engineering strategies. Both natural and synthetic biomaterials have been used for tissue repair. A variety of porous structures that promote cell adhesion, differentiation, and proliferation enable better implant integration with increasingly better

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Zhen, Le, Rebecca Darrow, Ningjing Chen, et al. "Soft, precision engineered porous, hydrogel scaffolds mechanically tailored toward applications in the central nervous system." Journal of Bioactive and Compatible Polymers 39, no. 6 (2024): 507–21. http://dx.doi.org/10.1177/08839115241287215.

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Diseases and traumatic injuries to the central nervous system (CNS) demand the development of new biomaterials to improve healing and treatment options. Matching material mechanical properties to specific tissues and optimizing material porous structures are central goals for improving biomaterials. However, biomaterials with both precision-controlled porous structures and brain-matched mechanical properties (low modulus) are still lacking. In this study, we developed soft hydrogel scaffolds with mechanical properties similar to that of CNS tissues, and a uniform 40 µm porous structure—40 µm p

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Takemura, Taro, Hong Song Fan, Toshiyuki Ikoma, M. Tanaka, and Nobutaka Hanagata. "Gene Expression Profile of Osteoblast-Like Cells on Calcium Phosphate Biomaterials." Key Engineering Materials 330-332 (February 2007): 1087–90. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.1087.

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Gene expression profile of osteoblast-like cells cultured on dense disk materials and porous materials of calcium phosphate ceramics was constructed from DNA microarray analyses. The profile revealed that gene expression patterns of porous materials were significantly different from those of dense disk materials. The porous materials had a capacity to induce expressions of genes involved in osteoblast differentiation, while dense disk materials regulated gene expressions related to osteoclastogenesis.

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Barsch, Friedrich, Andreas Mamilos, Volker H. Schmitt, et al. "In Vivo Comparison of Synthetic Macroporous Filamentous and Sponge-like Skin Substitute Matrices Reveals Morphometric Features of the Foreign Body Reaction According to 3D Biomaterial Designs." Cells 11, no. 18 (2022): 2834. http://dx.doi.org/10.3390/cells11182834.

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Synthetic macroporous biomaterials are widely used in the field of skin tissue engineering to mimic membrane functions of the native dermis. Biomaterial designs can be subclassified with respect to their shape in fibrous designs, namely fibers, meshes or fleeces, respectively, and porous designs, such as sponges and foams. However, synthetic matrices often have limitations regarding unfavorable foreign body responses (FBRs). Severe FBRs can result in unfavorable disintegration and rejection of an implant, whereas mild FBRs can lead to an acceptable integration of a biomaterial. In this context

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Zhang, Yin, Nengjian Yao, Fei Wang, Wenda Li, and Shengxiang Jiang. "A novel in situ self foaming method for the synthesis of porous calcium metaphosphate biomaterials." RSC Adv. 4, no. 104 (2014): 60007–16. http://dx.doi.org/10.1039/c4ra11097h.

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Porous ceramics were synthesized using an in situ self-foaming method. The method can be fabricated a porous biomaterials without pore-forming agents. The method can overcome the shortcomings of the pore-forming agent method.

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Nukavarapu, Syam P., Rao S. Bezwada, Deborah L. Dorcemus, Neeti Srivasthava, and Robert J. Armentano. "Novel Absorbable Polyurethane Biomaterials and Scaffolds for Tissue Engineering." MRS Proceedings 1621 (2014): 93–99. http://dx.doi.org/10.1557/opl.2014.359.

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ABSTRACTThis study reports a novel class of biodegradable polyurethane biomaterials and three-dimensional scaffolds for tissue engineering. Solvent casted polyurethane films were studied for biocompatibility by seeding with human bone marrow derived stromal cells. In order to develop a three-dimensional and porous structure, a dynamic solvent sintering method was applied to the polyurethanes for the first time. Microstructural studies on the sintered scaffolds reveal porous structure formation with bonding between the adjacent microspheres. In conclusion, this study establishes new polyurethan

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Shen, Teng Fei, Man Geng Lu, and Li Yan Liang. "Microporous Bio-Membrane Materials Based on High Molecular Weight Polylactide and Low Molecular Weight Poly(ethylene glycol)." Advanced Materials Research 567 (September 2012): 123–26. http://dx.doi.org/10.4028/www.scientific.net/amr.567.123.

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In this work, microporous membrane biomaterials based on high weight molecular polylactide (PLA) and low molecular weight poly(ethylene glycol) (PEG) using rapid solvent evaporation method were prepared and investigated. The effect of PEG segments added on the thermal and degradation behaviors was studied. According to the results, produced PLA/PEG biomaterial has lower glass transition temperature (Tg)in comparison with neat PLA. It was also found that the degradation rates of the PLA/PEG biomaterials were significantly increased with adding of PEG, which explained by increasing hydrophilic g

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James, Roshan, Paulos Mengsteab, and Cato T. Laurencin. "Regenerative Engineering: Studies of the Rotator Cuff and other Musculoskeletal Soft Tissues." MRS Advances 1, no. 18 (2016): 1255–63. http://dx.doi.org/10.1557/adv.2016.282.

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ABSTRACT‘Regenerative Engineering’ is the integration of advanced materials science, stem cell science, physics, developmental biology and clinical translation to regenerate complex tissues and organ systems. Advanced biomaterial and stem cell science converge as mechanisms to guide regeneration and the development of prescribed cell lineages from undifferentiated stem cell populations. Studies in somite development and tissue specification have provided significant insight into pathways of biological regulation responsible for tissue determination, especially morphogen gradients, and paracrin

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Renaud, Matthieu, Philippe Bousquet, Gerard Macias, et al. "Allogenic Stem Cells Carried by Porous Silicon Scaffolds for Active Bone Regeneration In Vivo." Bioengineering 10, no. 7 (2023): 852. http://dx.doi.org/10.3390/bioengineering10070852.

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To date, bone regeneration techniques use many biomaterials for bone grafting with limited efficiencies. For this purpose, tissue engineering combining biomaterials and stem cells is an important avenue of development to improve bone regeneration. Among potentially usable non-toxic and bioresorbable scaffolds, porous silicon (pSi) is an interesting biomaterial for bone engineering. The possibility of modifying its surface can allow a better cellular adhesion as well as a control of its rate of resorption. Moreover, release of silicic acid upon resorption of its nanostructure has been previousl

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Dejaco, Alexander, Vladimir S. Komlev, Jakub Jaroszewicz, Wojciech Swieszkowski, Christian Hellmich, and Masoud Mozafari. "Discussion: Fracture safety of double-porous hydroxyapatite biomaterials." Bioinspired, Biomimetic and Nanobiomaterials 5, no. 4 (2016): 176–77. http://dx.doi.org/10.1680/jbibn.16.00025.

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Chikhi, M. "Effective thermal conductivity of porous biomaterials: Numerical investigation." Journal of Building Engineering 32 (November 2020): 101763. http://dx.doi.org/10.1016/j.jobe.2020.101763.

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Hedayati, R., S. Amin Yavari, and A. A. Zadpoor. "Fatigue crack propagation in additively manufactured porous biomaterials." Materials Science and Engineering: C 76 (July 2017): 457–63. http://dx.doi.org/10.1016/j.msec.2017.03.091.

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Mattioli-Belmonte, M., G. Lucarini, A. Zizzi, A. Alhuwalia, and G. Vozzi. "A comparative study of porous and engineered biomaterials." Biomedicine & Pharmacotherapy 62, no. 8 (2008): 487–88. http://dx.doi.org/10.1016/j.biopha.2008.07.003.

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Kohlhauser, C., C. Hellmich, C. Vitale-Brovarone, A. R. Boccaccini, A. Rota, and J. Eberhardsteiner. "Ultrasonic Characterisation of Porous Biomaterials Across Different Frequencies." Strain 45, no. 1 (2009): 34–44. http://dx.doi.org/10.1111/j.1475-1305.2008.00417.x.

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