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Journal articles on the topic 'Porous titanium implant'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Zhang, Xuesong, Guoquan Zheng, Jiaqi Wang, et al. "Porous Ti6Al4V Scaffold Directly Fabricated by Sintering: Preparation andIn VivoExperiment." Journal of Nanomaterials 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/205076.

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The interface between the implant and host bone plays a key role in maintaining primary and long-term stability of the implants. Surface modification of implant can enhance bone ingrowth and increase bone formation to create firm osseointegration between the implant and host bone and reduce the risk of implant losing. This paper mainly focuses on the fabricating of 3-dimensiona interconnected porous titanium by sintering of Ti6Al4V powders, which could be processed to the surface of the implant shaft and was integrated with bone morphogenetic proteins (BMPs). The structure and mechanical prope

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2

Takemoto, Mitsuru, Shunsuke Fujibayashi, Masashi Neo, et al. "Bone Ingrowth Into Porous Bioactive Titanium Implant for Load-Bearing Use: Experimental Study Using a Novel Canine Anterior Interbody Fusion Model." Key Engineering Materials 330-332 (February 2007): 987–90. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.987.

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We have developed a porous titanium implant sintered with spacer particles (porosity = 50 %, average pore size ± standard deviation = 303 ± 152 !m, yield compression strength = 100MPa). This porous titanium was successfully treated with chemical and thermal treatment that gives a bioactive micro-porous titania layer on the titanium surface, and it is expected as effective biomaterial for biological fixation on load bearing condition. In this study, ten adult female beagle dogs underwent anterior lumbar interbody fusion at L6-7 using either BT-implant or non-treated implant (NT-implant), then f

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Takemoto, Mitsuru, Shunsuke Fujibayashi, Tomiharu Matsushita, J. Suzuki, Tadashi Kokubo, and Takashi Nakamura. "Enhanced Osteoinductivity of Porous Titanium Implant by Sodium Removal." Key Engineering Materials 309-311 (May 2006): 1315–20. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.1315.

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The aim of this study was to optimize the surface treatment and to accelerate the osteoinductivity of porous bioactive titanium implant. Previous studies have reported that sodium removal with hot water treatment converts sodium titanate on the surface of an alkali-treated titanium plate into titania with a specific structure, which has better bioactivity than sodium titanate. We developed a dilute hydrochloric acid (HCl) treatment for porous titanium, which removed sodium from the complexly shaped porous structure more effectively than conventional hot water treatment. Three types of surface

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Barbosa, Luzinete Pereira, Lucio Salgado, N. Filho Karsokas, and Márcia Kazumi Nagamine. "Characterization of HDH Titanium Powder for Biomaterial Applications." Materials Science Forum 660-661 (October 2010): 188–93. http://dx.doi.org/10.4028/www.scientific.net/msf.660-661.188.

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Several materials have been used as surgical implants since the 16th century. Materials can be implanted in the human body; however, the choice of the appropriate material is based on the required mechanical, physical, chemical, and biological properties. Until now two classes of metals namely stainless steel and cobalt-chromium-molybdenum alloys became known as materials for implant applications. They were considered suitable for surgical implant procedures but many researchers and surgeons were not completely satisfied with their performance. The main problem of the modern science is to find

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5

Alshehri, Fahad, Mohammed Alshehri, Terrence Sumague, et al. "Evaluation of Peri-Implant Bone Grafting Around Surface-Porous Dental Implants: An In Vivo Study in a Goat Model." Materials 12, no. 21 (2019): 3606. http://dx.doi.org/10.3390/ma12213606.

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Dental implants with surface-porous designs have been recently developed. Clinically, peri-implant bone grafting is expected to promote early osseointegration and bone ingrowth when applied with surface-porous dental implants in challenging conditions. The aim of this study was to comparatively analyze peri-implant bone healing around solid implants and surface-porous implants with and without peri-implant bone grafting, using biomechanical and histomorphometrical assessment in a goat iliac bone model. A total of 36 implants (4.1 mm wide, 11.5 mm long) divided into three groups, solid titanium

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Tanaka, Kojiro, Mitsuru Takemoto, Shunsuke Fujibayashi, et al. "Long-Term Study of Osteoconductivity of Bioactive Porous Titanium Metals: Effect of Sodium Removal by Dilute HCl Treatment." Key Engineering Materials 396-398 (October 2008): 353–56. http://dx.doi.org/10.4028/www.scientific.net/kem.396-398.353.

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In a previous study, we have reported that sodium removal by dilute hydrochloric acid (HCl) converted the sodium titanate layer on the surface of an alkali-treated porous titanium into titania with a specific structure that has better bioactivity than sodium titanate. We have shown that a porous titanium with this treatment have good osteoinductivity in soft tissue of canines. In the present study, we investigated the effect of this treatment on the osteoconductive abilities of porous bioactive titanium implant in the long term. Three types of surface treatments were applied: (a) no treatment

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7

Sidun, Jarosław, and Jan Ryszard Dąbrowski. "Bone Ingrowth Processes on Porous Metalic Implants." Solid State Phenomena 147-149 (January 2009): 776–81. http://dx.doi.org/10.4028/www.scientific.net/ssp.147-149.776.

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The surface of an endosseous implant has fundamental importance in forming mechanical and chemical connection with osseous tissue. One of the methods of enlarging area is using technology of powder metallurgy. The paper presents research regarding osteointegration of porous materials for implants made for Co-Cr-Mo and titanium with Bioglass type-S2. The research was made on the castrated goats averaging one year of age, from this oneself herds. Bone growth process on surfaces of implants made with additional bioglass was significantly intense. The amount of osseous tissue and the number of con

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Takemoto, Mitsuru, Shunsuke Fujibayashi, Tomiharu Matsushita, J. Suzuki, Tadashi Kokubo, and Takashi Nakamura. "Mechanical Properties and Osteoconductivity of Porous Bioactive Titanium Metal." Key Engineering Materials 284-286 (April 2005): 263–66. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.263.

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Porous bioactive titanium implant was produced by plasma-spray method and succeeding chemical and thermal treatment. This porous titanium implant possess a porosity of 40% and complex interconnective porous structure. Mechanical property of porous titanium was characterized for compressive and 4-point bending properties, as well as compressive fatigue. Bone tissue response and biocompatibility of porous bioactive titanium implant was evaluated by in vivo osteoconductive model. Ultimate compression strength and bending strength were 280 and 101 MPa. Bone ingrowth showed significant increases in

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9

Shayganpour, Amirreza, Alberto Rebaudi, Pierpaolo Cortella, Alberto Diaspro, and Marco Salerno. "Electrochemical coating of dental implants with anodic porous titania for enhanced osteointegration." Beilstein Journal of Nanotechnology 6 (November 20, 2015): 2183–92. http://dx.doi.org/10.3762/bjnano.6.224.

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Clinical long-term osteointegration of titanium-based biomedical devices is the main goal for both dental and orthopedical implants. Both the surface morphology and the possible functionalization of the implant surface are important points. In the last decade, following the success of nanostructured anodic porous alumina, anodic porous titania has also attracted the interest of academic researchers. This material, investigated mainly for its photocatalytic properties and for applications in solar cells, is usually obtained from the anodization of ultrapure titanium. We anodized dental implants

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10

Likibi, Fidele, Michel Assad, Christine Coillard, Gilles Chabot, and Charles-H. Rivard. "PERIPROSTHETIC BONE DENSITY CHANGES EVALUATION USING COMPUTED TOMOGRAPHY." Hirurgiâ pozvonočnika, no. 4 (December 15, 2005): 072–76. http://dx.doi.org/10.14531/ss2005.4.72-76.

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The aim of this study was to examine the effect of the presence of two types of metallic intervertebral lumbar fusion implants (a porous nitinol and a hollow titanium cylindrical implants) in the implant peripheral tissue after 3, 6 and 12 months post-implantation in a lumbar sheep model in order to evaluate and compare the biofunctionality and biocompatibility of both implants. 19 sheep were used to evaluate this bone density variation using computer tomography (CT). 16 of them received both implants at either level L2–L3 or L4–L5 and 3 other non-treated animals were used as controls. Results

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11

Takemoto, Mitsuru, Shunsuke Fujibayashi, Masashi Neo, et al. "A porous bioactive titanium implant for spinal interbody fusion: an experimental study using a canine model." Journal of Neurosurgery: Spine 7, no. 4 (2007): 435–43. http://dx.doi.org/10.3171/spi-07/10/435.

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Object Porous biomaterials with adequate pore structure and appropriate mechanical properties are expected to provide a new generation of devices for spinal interbody fusion because of their potential to eliminate bone grafting. The purpose of this study was to evaluate the fusion characteristics of porous bioactive titanium implants using a canine anterior interbody fusion model. Methods Porous titanium implants sintered with volatile spacer particles (porosity 50%, average pore size 303 μm, compressive strength 116.3 MPa) were subjected to chemical and thermal treatments that give a bioactiv

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12

Hong, Ji-Youn, Seok-Yeong Ko, Wonsik Lee, Yun-Young Chang, Su-Hwan Kim, and Jeong-Ho Yun. "Enhancement of Bone Ingrowth into a Porous Titanium Structure to Improve Osseointegration of Dental Implants: A Pilot Study in the Canine Model." Materials 13, no. 14 (2020): 3061. http://dx.doi.org/10.3390/ma13143061.

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A porous titanium structure was suggested to improve implant stability in the early healing period or in poor bone quality. This study investigated the effect of a porous structure on the osseointegration of dental implants. A total of 28 implants (14 implants in each group) were placed in the posterior mandibles of four beagle dogs at 3 months after extraction. The control group included machined surface implants with an external implant–abutment connection, whereas test group implants had a porous titanium structure added to the apical portion. Resonance frequency analysis (RFA); removal tor

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13

Tikhilov, R. M., I. I. Shubnyakov, A. O. Denisov, et al. "BONE AND SOFT TISSUES INTEGRATION IN POROUS TITANIUM IMPLANTS (EXPERIMENTAL RESEARCH)." Traumatology and Orthopedics of Russia 24, no. 2 (2018): 95–107. http://dx.doi.org/10.21823/2311-2905-2018-24-2-95-107.

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Aim. It’s common that revision arthroplasty of the large joints demands replacing of bone defects of irregular geometrical shapes and simultaneous restoring of support ability and ability to integrate surrounding muscular and tendinous structures into an implant that is required for a complete restoration of joint function.The purpose.To experimentally study the process of integration for muscular and bone tissue as well as tendinous and ligamentous structures into porous titanium materials.Material and methods. During in vivo experiment the authors created a standardized bone defect in 6 rabb

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Ko, S. Y., J. Y. Hong, W. Lee, Y. Y. Chang, K. B. Park, and J. H. Yun. "Osteoconductivity of Porous Titanium Structure on Implants in Osteoporosis." Journal of Dental Research 100, no. 10 (2021): 1178–85. http://dx.doi.org/10.1177/00220345211023724.

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In compromised bone conditions such as osteoporosis, developments of the implant surface are necessary to secure the stability of implants. This study investigated the effect of the surface porous titanium structure (PS) on the osseointegration of implants in osteoporotic bone. Bilateral ovariectomy (OVX) was performed in 4 female beagle dogs to induce osteoporosis for 32 wk. Success of induction was based on the evaluation of bone mineral density by Hounsfield units (HU) in computed tomography images. Posterior teeth in both mandibles were extracted 1 wk after OVX, and a total of 30 implants

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15

Rodríguez, Ángel, Paloma Trueba, José Manuel Amado, et al. "Surface Modification of Porous Titanium Discs Using Femtosecond Laser Structuring." Metals 10, no. 6 (2020): 748. http://dx.doi.org/10.3390/met10060748.

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The failure of titanium implants is associated with two main problems that include the bone resorption and fracture of the surrounding bone tissue (stiffness incompatibility) and implant loosening (poor osseointegration). The development of porous titanium implants with low Young modulus solve the stress shielding phenomenon, while the modification of the implant surface must be implemented to promote a fast bond between the implant and bone. In this work, femtosecond laser micromachining was applied to modify the topography of the surface of Ti porous samples obtained by a space-holder techni

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16

Shi, Jianping, Huixin Liang, Jie Jiang, Wenlai Tang, and Jiquan Yang. "Design and Performance Evaluation of Porous Titanium Alloy Structures for Bone Implantation." Mathematical Problems in Engineering 2019 (October 9, 2019): 1–9. http://dx.doi.org/10.1155/2019/5268280.

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Implant parts prepared by traditional design and manufacturing methods generally have problems of high stiffness and heavy self-weight, which may cause stress shielding effect between the implanted part and the host bone, and eventually cause loosening of the implanted part. Based on the implicit surface function equations, several porous implant models with controlled pore structure were designed. By adjusting the parameters, the apparent elastic modulus of the porous implant model can be regulated. The biomechanical simulation experiment was performed using CAE software to simulate the stres

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17

Groessner-Schreiber, B., and R. S. Tuan. "Enhanced extracellular matrix production and mineralization by osteoblasts cultured on titanium surfaces in vitro." Journal of Cell Science 101, no. 1 (1992): 209–17. http://dx.doi.org/10.1242/jcs.101.1.209.

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Long-term stability of orthopaedic and dental implants depends on the integration of the artificial material into the surrounding bone tissue. The physical and chemical properties of implants, including those made of metals such as titanium, are thought to influence osseointegration. Despite the known importance of this interface, little is known about the factors that promote its formation. In this study, chick embryonic calvarial osteoblasts were cultured in vitro on smooth, rough-textured and porous-coated titanium surfaces and examined for morphology, biosynthesis of extracellular matrix a

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18

Brentel, Aline Scalone, Luana Marotta Reis de Vasconcellos, Marize Varella Oliveira, et al. "Histomorphometric analysis of pure titanium implants with porous surface versus rough surface." Journal of Applied Oral Science 14, no. 3 (2006): 213–18. http://dx.doi.org/10.1590/s1678-77572006000300013.

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The purpose of this study was to analyze the bone repair around commercially pure titanium implants with rough and porous surface, fabricated using powder metallurgy technique, after their insertion in tibiae of rabbits. Seven male rabbits were used. Each animal received 3 porous-surface implants in the left tibia and 3 rough-surface implants in the right tibia. The rabbits were sacrificed 4 weeks after surgery and fragments of the tibiae containing the implants were submitted to histological and histomorphometric analyses to evaluate new bone formation at the implant-bone interface. Means (%)

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Eltlhawy, Basma, Tawfik El-Midany, Noha Fouda, and Ibrahim Eldesouky. "Finite Element Assessment of a Porous Tibial Implant Design Using Rhombic Dodecahedron Structure." Solid State Phenomena 318 (May 2021): 71–81. http://dx.doi.org/10.4028/www.scientific.net/ssp.318.71.

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The current research presents a novel porous tibia implant design based on porous structure. The implant proximal portion was designed as a porous rhombic dodecahedron structure with 500 μm pore size. Finite element method (FEM) was used to assess the stem behavior under compressive loading compared to a solid stem model. CATIA V5R18 was used for modeling both rhombic dodecahedron and full solid models. Static structural analysis was carried out using ANSYS R18.1 to asses the implant designs. The results indicated enhanced clinical performance of tibial-knee implants compared to the solid tita

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20

Beckmann, Nicholas A., Rudi G. Bitsch, Mareike Schonhoff, Klaus-Arno Siebenrock, Martin Schwarze, and Sebastian Jaeger. "Comparison of the Primary Stability of Porous Tantalum and Titanium Acetabular Revision Constructs." Materials 13, no. 7 (2020): 1783. http://dx.doi.org/10.3390/ma13071783.

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Adequate primary stability of the acetabular revision construct is necessary for long-term implant survival. The difference in primary stability between tantalum and titanium components is unclear. Six composite hemipelvises with an acetabular defect were implanted with a tantalum augment and cup, using cement fixation between cup and augment. Relative motion was measured at cup/bone, cup/augment and bone/augment interfaces at three load levels; the results were compared to the relative motion measured at the same interfaces of a titanium cup/augment construct of identical dimensions, also imp

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Silva de Medeiros, Waléria, Marize Varella de Oliveira, and José Mauro Granjeiro. "Evaluation of Biomimetic Solution for Coating Powder Metallurgy Porous Titanium Samples." Materials Science Forum 591-593 (August 2008): 703–7. http://dx.doi.org/10.4028/www.scientific.net/msf.591-593.703.

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In order to improve implant-bone attachment, porous titanium has been used to achieve the ingrowth of bone tissue within the porous structure. Although this biomaterial has shown efficient bone adhesion for orthopedic and dental implants, the ideal surface must have chemical bonds at the implant-bone interface. In this work, samples of pure porous titanium were produced by powder metallurgy technique and submitted to biomimetic process in order to evaluate the material’s bioactivity and to enhance its osteoconductivity. The samples were immersed in modified simulated body fluid (mSBF) which in

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Bobik, G., J. Żmudzki, and K. Majewska. "Bone tissue loads around titanium femoral implant and coated with porous layer." Journal of Achievements in Materials and Manufacturing Engineering 2, no. 90 (2018): 77–84. http://dx.doi.org/10.5604/01.3001.0012.8386.

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Purpose: Difference in the mechanical properties of bone and stiffer femoral implant causes bone tissue resorption, which may result in implant loosening and periprosthetic fractures. The introduction of porous material reduces the stiffness of the implant. The aim of the study was to analyse the influence of porous shell of femoral revision implant on bone tissue loading distribution with use the finite element method. Design/methodology/approach: Load transfer in the femur has been investigated using the finite element method (Ansys). Cementless implant models were placed in the anatomical f

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Hu, Xiao-Fan, Ya-Fei Feng, Geng Xiang, Wei Lei, and Lin Wang. "Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone." Journal of Materials Chemistry B 6, no. 15 (2018): 2274–88. http://dx.doi.org/10.1039/c7tb03247a.

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Maksimkin, Aleksey V., Fedor S. Senatov, Kirill Niaza, Tarek Dayyoub, and Sergey D. Kaloshkin. "Ultra-High Molecular Weight Polyethylene/Titanium-Hybrid Implant for Bone-Defect Replacement." Materials 13, no. 13 (2020): 3010. http://dx.doi.org/10.3390/ma13133010.

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A hybrid implant with a structure mimicking that of natural bone was developed. Titanium alloy Ti–6Al–4V prepared with three-dimensional (3D)-printing technology was used to simulate the cortical-bone layer. The mismatch in the mechanical properties of bone and titanium alloy was solved by creating special perforations in the titanium’s surface. Porous ultra-high molecular weight polyethylene (UHMWPE) with high osteogenous properties was used to simulate the cancellous-bone tissue. A method for creating a porous UHMWPE structure inside the titanium reinforcement is proposed. The porous UHMWPE

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Silva de Medeiros, Waléria, Luiz Carlos Pereira, Robson Pacheco Pereira, and Marize Varella de Oliveira. "Characterization of CaP Coating Deposited on Porous Titanium." Key Engineering Materials 396-398 (October 2008): 307–10. http://dx.doi.org/10.4028/www.scientific.net/kem.396-398.307.

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Synthetic Hydroxyapatite (HA) has been used as coating in order to enhance biocompatibility of titanium implants. Osseointegration at the implant-bone interface can be positively affected by the presence of HA coating and other biocompatible calcium phosphates (CaP) deposited on titanium implants, due to the high biocompatibility of these bioceramics. The biomimetic process is based on the nucleation and growth of a bioceramic film onto a substrate immersed in a body fluid solution (SBF) and it can be applied to deposit CaP coatings onto metallic substrates. The present work presents results o

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Lu, Xia, Li Ang Xing, Pei Zhi Wang, and Jun Fu. "Fabrication and Bioactivity of Porous Titanium Implant." Key Engineering Materials 342-343 (July 2007): 613–16. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.613.

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The aim of this study is to fabricate an implant framework for tissue engineering by sintering titanium beads and coating with hydroxyapatite and test its biocompatibility and bioactivity in vitro. The porous titanium with and without hydroxyapatite coating were involved in study groups. Osteoblastic proliferation, activity of alkaline phosphatase, mRNA of osteocalcin and bone sialoprotein were detected by MTT-assay, ALP test and real-time polymerase chain reaction respectively. The results indicated that the porous titanium material with/without HA coating could promote osteoblastic prolifera

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Lung, Christie Y. K., Mohamed M. Abdalla, Chun Hung Chu, Iris Yin, Sofiya-Roksolana Got, and Jukka P. Matinlinna. "A Multi-Element-Doped Porous Bioactive Glass Coating for Implant Applications." Materials 14, no. 4 (2021): 961. http://dx.doi.org/10.3390/ma14040961.

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Objectives: The objectives of the study were (1) to develop a novel multi-element-doped porous 58S bioactive glass coating for titanium implants and (2) to investigate the physiochemical, cell cytotoxic and antibacterial properties of this novel coating for titanium implants. Methods: This study employed the sol–gel method to develop a silver-, cobalt (II) oxide- and titanium dioxide-doped 58S bioactive glass coating. The surface topography and in vitro bioactivity of the new bioactive glass-coated implants were studied using scanning electron microscopy (SEM) and energy-dispersive X-ray spect

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28

Bondarenko, Stanislav, Ninel Dedukh, Volodymyr Filipenko, Mandus Akonjom, Ahmed Amine Badnaoui, and Ran Schwarzkopf. "Comparative analysis of osseointegration in various types of acetabular implant materials." HIP International 28, no. 6 (2018): 622–28. http://dx.doi.org/10.1177/1120700018759314.

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Background: There is a lack of comparative data on osseointegration (BIC) of acetabular cup surfaces in hip arthroplasty in both normal bone mineral density and in conditions of osteoporosis. Aim: To compare osseointegration of acetabular implants with various types of surfaces in an animal model with normal and osteoporotic bone tissue. Material and Methods: The study was performed on 60 rats. To simulate osteoporosis ovariectomy was performed in 30 animals. Thirty healthy rats served as controls. In standardised defects of the distal metadiaphysis of the femur we implanted: porous tantalum T

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Wally, Zena, William van Grunsven, Frederik Claeyssens, Russell Goodall, and Gwendolen Reilly. "Porous Titanium for Dental Implant Applications." Metals 5, no. 4 (2015): 1902–20. http://dx.doi.org/10.3390/met5041902.

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Duncan, Warwick J., Min-Ho Lee, Tae-Sung Bae, Sook-Jeong Lee, Jennifer Gay, and Carolina Loch. "Anodisation Increases Integration of Unloaded Titanium Implants in Sheep Mandible." BioMed Research International 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/857969.

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Spark discharge anodic oxidation forms porous TiO2films on titanium implant surfaces. This increases surface roughness and concentration of calcium and phosphate ions and may enhance early osseointegration. To test this, forty 3.75 mm × 13 mm titanium implants (Megagen, Korea) were placed into healed mandibular postextraction ridges of 10 sheep. There were 10 implants per group: RBM surface (control), RBM + anodised, RBM + anodised + fluoride, and titanium alloy + anodised surface. Resonant frequency analysis (RFA) was measured in implant stability quotient (ISQ) at surgery and at sacrifice af

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Arab, Hamid Reza, Hamid Reza Boostani, Amir Moeintaghavi, and Farid Shiezadeh. "Porous Titanium Granules for Sinus Floor Augmentation: A Case Series Study." Open Dentistry Journal 13, no. 1 (2019): 339–45. http://dx.doi.org/10.2174/1874210601913010339.

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Background: Sinus grafting with autogenous bone and other bone substitutes has been shown to be a safe technique with high predictability of success, but it has not been determined which of these materials provide better osteogenic potential. The aim of the present study was to clinically and radiographically evaluate the use of Natix™ grafting material in maxillary sinus elevation procedures with simultaneous implant placement in humans. Materials and Methods: Fifteen patients (6 women and 9 men) requiring augmentation of the maxillary sinus before implant placement were voluntarily enrolled

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Godlewski(, Bartosz, and Maciej Dominiak. "Advantages and Disadvantages of the Use of Various Types of Interbody Implants in Cervical Spine Surgery. Critical Review of the Literature." Ortopedia Traumatologia Rehabilitacja 22, no. 4 (2020): 213–22. http://dx.doi.org/10.5604/01.3001.0014.3457.

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Background. Most cervical spine procedures in patients with degenerative disc disease involve discectomy and removal of osteophytes in posterior vertebral body surfaces followed by interbody stabilisation with an interbody implant. Interbody implants are made of a variety of materials, differing in structural design, shape and surface topography. Considering that fusion between the implant and host bone is crucial for long-term positive outcomes, the choice of an appropriate implant is significantly important clinically and continues to be an important area of study. Material and methods. Rel

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Eldesouky, Ibrahim, Hassan El-Hofy, and Ola Harrysson. "Research: Design and Analysis of a Low-Stiffness Porous Hip Stem." Biomedical Instrumentation & Technology 51, no. 6 (2017): 474–82. http://dx.doi.org/10.2345/0899-8205-51.6.474.

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Abstract Two major problems are associated with total hip replacement: 1) stress shielding and 2) the adverse tissue reaction to certain elements of the implant material. In this regard, a porous implant provides lower stiffness and vacancies for bone ingrowth, making it more suitable for the human bone compared with a solid stem. Moreover, second-generation titanium biomedical alloys, such as TNZT (Ti35Nb7Zr5Ta) and TMZF (Ti12Mo6Zr2Fe), have been introduced to prevent the adverse tissue reactions related to aluminum and vanadium elements of the popular Ti6Al4V alloy. In the current work, an a

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Tailor, Satish, N. Vashishtha, Ankur Modi, and SC Modi. "Thermally Sprayed Porous PEEK Coating for Biomedical Implants." Journal of Thermal Spray and Engineering 1, no. 1 (2018): 32–36. http://dx.doi.org/10.52687/2582-1474/116.

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The present study reports the novel results of microstructural and mechanical properties of highly porous Polyetheretherketone (PEEK) coating. PEEK is already considered as a material for biomedical implants. A new kind of approach is proposed for manufacturing of highly porous PEEK coating on a dense PEEK coating for orthopedic implants and successfully implemented to create novel biomimetic porous PEEK coating by means of thermal spray process. To imitate the structure of natural bone, as-sprayed top PEEK coating has porosity of more than 60% vol. and pore sizes of 30-80 μm. Mechanical resul

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Freitas, Gileade P., Helena B. Lopes, Evandro C. Martins-Neto, Paulo T. de Oliveira, Marcio M. Beloti, and Adalberto L. Rosa. "Effect of Surface Nanotopography on Bone Response to Titanium Implant." Journal of Oral Implantology 42, no. 3 (2016): 240–47. http://dx.doi.org/10.1563/aaid-joi-d-14-00254.

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Clinical success of implant therapy is directly related to titanium (Ti) surface properties and the quality of bone tissue. The treatment of Ti implants with H2SO4/H2O2 is a feasible, reproducible, and low-cost technique to create surface nanotopography (Ti-Nano). As this nanotopography induces osteoblast differentiation, we hypothesized that it may affect bone response to Ti. Thus, this study was designed to evaluate the bone response to a machined Ti implant treated with H2SO4/H2O2 to generate Ti-Nano and to compare it with a commercially available microtopographic Ti implant (Ti-Porous). Im

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Wang, Yaling, Xianshuai Chen, Chunyu Zhang, et al. "Studies on the performance of selective laser melting porous dental implant by finite element model simulation, fatigue testing and in vivo experiments." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 233, no. 2 (2018): 170–80. http://dx.doi.org/10.1177/0954411918816114.

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Biomaterials have been widely used for stomatological reconstructive surgery in recent years. Many studies have demonstrated that the porous structure of an implant promotes bone ingrowth and its stiffness can be controlled via the design of the porosity. Although some researchers have paid attention to investigating the porous structure for dental implants, the biomechanical properties and osseointegration have not been well studied. In this study, finite element analysis and experiments have been used to evaluate the biomechanical performance and osseointegration of dental implants with poro

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Kawai, Toshiyuki, Mitsuru Takemoto, Shunsuke Fujibayashi, et al. "Enhanced Osteoconductivity of Positively Charged Titanium Metal." Key Engineering Materials 493-494 (October 2011): 787–90. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.787.

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We previously found that a positively charged Ti metal has a higher apatite forming ability in vitro than a non-charged Ti metal. For in vivo analysis using a rabbit model, two types of Ti metal were examined: porous Ti metals heat-treated subsequent to a mixed acid treatment (MHs) and porous Ti metals not heat-treated subsequent to the same mixed acid treatment (MOs). Although MHs and MOs had the same macro- and micro-structure, they had different surface charges. MHs, considered positively charged, had significantly higher bone ingrowth than MOs, considered charged zero. Similarly, MHs had s

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Elias, Carlos Nelson, Patricia Abdo Gravina, Costa e. Silva Filho, and Pedro Augusto de Paula Nascente. "Preparation of Bioactive Titanium Surfaces via Fluoride and Fibronectin Retention." International Journal of Biomaterials 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/290179.

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Statement of Problem. The chemical or topographic modification of the dental implant surface can affect bone healing, promote accelerated osteogenesis, and increase bone-implant contact and bonding strength.Objective. In this work, the effects of dental implant surface treatment and fibronectin adsorption on the adhesion of osteoblasts were analyzed.Materials and Methods. Two titanium dental implants (Porous-acid etching and PorousNano-acid etching followed by fluoride ion modification) were characterized by high-resolution scanning electron microscopy, atomic force microscopy, and X-ray diffr

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Rüegg, Jasmine, Ralf Schumacher, Franz E. Weber, and Michael de Wild. "Mechanical anisotropy of titanium scaffolds." Current Directions in Biomedical Engineering 3, no. 2 (2017): 607–11. http://dx.doi.org/10.1515/cdbme-2017-0127.

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AbstractThe clinical performance of an implant, e.g. for the treatment of large bone defects, depends on the implant material, anchorage, surface topography and chemistry, but also on the mechanical properties, like the stiffness. The latter can be adapted by the porosity. Whereas foams show isotropic mechanical properties, digitally modelled scaffolds can be designed with anisotropic behaviour. In this study, we designed and produced 3D scaffolds based on an orthogonal architecture and studied its angle-dependent stiffness. The aim was to produce scaffolds with different orientations of the m

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Marenzi, Gaetano, Gianrico Spagnuolo, Josè Camilla Sammartino, Roberta Gasparro, Alberto Rebaudi, and Marco Salerno. "Micro-Scale Surface Patterning of Titanium Dental Implants by Anodization in the Presence of Modifying Salts." Materials 12, no. 11 (2019): 1753. http://dx.doi.org/10.3390/ma12111753.

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The bone-implant interface influences peri-implant bone healing and osseointegration. Among various nano-engineering techniques used for titanium surface modification, anodization is a simple, high-throughput and low-cost process, resulting in a nanoporous oxide coating which can promote osseointegration and impart antimicrobial and immunomodulatory properties. We anodized rounded tip dental implants of commercial grade titanium in aqueous phosphoric acid modified with calcium and potassium acetate, and characterized the resulting surface morphology and composition with scanning electron micro

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Ng, Sabrina Livia, Subhabrata Das, Yen-Peng Ting, Raymond Chung Wen Wong, and Nattharee Chanchareonsook. "Benefits and Biosafety of Use of 3D-Printing Technology for Titanium Biomedical Implants: A Pilot Study in the Rabbit Model." International Journal of Molecular Sciences 22, no. 16 (2021): 8480. http://dx.doi.org/10.3390/ijms22168480.

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Background: Titanium has been used in osteosynthesis for decades and its compatibility and safety is unquestioned. Studies have shown that there is release and collection of titanium in the organ systems with little note of toxicity. The gold standard is considered to be titanium osteosynthesis plate produced by milling methods. The use of customized titanium plates produced with 3D printing, specifically direct metal laser sintering, have found increasing use in recent years. It is unknown how much titanium is released in these printed titanium implants, which is known to be potentially porou

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Goia, Tamiye Simone, Kalan Bastos Violin, Marcelo Yoshimoto, José Carlos Bressiani, and Ana Helena Almeida Bressiani. "Osseointegration of Titanium Alloy Macroporous Implants Obtained by PM with Addition of Gelatin." Advances in Science and Technology 76 (October 2010): 259–63. http://dx.doi.org/10.4028/www.scientific.net/ast.76.259.

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Studies of titanium and its alloys commonly used as biomaterials aim to improve bone-implant interface related problems, which may determine the quality, bone repairing time and therefore the implant clinical success. The goal of this study was to evaluate, in rats, osseointegration of macroporous implants produced by powder metallurgy (PM) method with controlled addition of gelatin. As control group, samples of commercially pure titanium (cpTi) and Ti-13Nb-13Zr alloy obtained by the PM process were used. To obtaining the porous samples, at most 15% in weight of gelatin was added to metallic p

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Xavier, Samuel Porfírio, Karen Emi Ikuno, and Marconi Gonzaga Tavares. "Enhanced bone apposition to Brazilian microrough titanium surfaces." Brazilian Dental Journal 21, no. 1 (2010): 18–23. http://dx.doi.org/10.1590/s0103-64402010000100003.

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It has recently been reported that machined and microrough (micro) Brazilian titanium (Ti) implants have good production standards. The aim of this study was to evaluate in vivo bone formation around 2 different implant surfaces placed in dog's mandible. Thirty-two screw-typed Ti implants were used in this study. Mandibular premolars were extracted in 8 dogs and, after 12 weeks, 2 machined (Neodent Titamax, Brazil) and 2 micro implants (Neodent Titamax Porous, Brazil) were placed in each animal. Biopsies were taken at 3 and 8 weeks post-implantation and stained with Stevenel's blue and Alizari

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Takemoto, Mitsuru, Shunsuke Fujibayashi, B. Otsuki, Tomiharu Matsushita, Tadashi Kokubo, and Takashi Nakamura. "3-D Analysis of Pore Structure of Porous Biomaterials Using Micro Focus X-Ray Computed Tomography." Key Engineering Materials 309-311 (May 2006): 1095–98. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.1095.

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Generally, characterizations of pore structures of porous biomaterials are mainly based on 2-dimensional (2-D) analysis using cross sectional micrographs. However, interconnectivity of each pore may be more important factor, when tissue ingrowth into deeper pores is considered. In this paper, using micro-CT imaging with 3-D image processing software, analyses of porous material based on 3-demensional (3-D) geometrical considerations were successfully performed. Plasmasprayed porous titanium implant (PT) and four types of sintered porous titanium implants (ST50- 200, ST50-500, ST70-200, and ST7

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Mirgazizov, M. Z., M. A. Chobonyan, V. I. Itin, and V. E. Gunther. "Production technology and strength properties of porous permeable materials based on titanium and titanium nickelide for dental implantology." Kazan medical journal 74, no. 1 (1993): 70–72. http://dx.doi.org/10.17816/kazmj64619.

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Currently, for dental implantology, structures from porous permeable materials based on titanium and titanium nickelide have been proposed and substantiated. The main advantages of titanium in comparison with other medical materials based on metals and alloys (stainless steel, alloys based on cobalt, chromium, nickel) are high elasticity, sufficient mechanical strength, and increased corrosion resistance in biological media. Porous titanium also retains these qualities. However, titanium, including porous titanium, has some disadvantages: low shear resistance, low wear resistance, and increase

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Kim, Yeon Wook. "Surface Modification of Ti Dental Implants by Grit-Blasting and Micro-Arc Oxidation." Advanced Materials Research 47-50 (June 2008): 467–70. http://dx.doi.org/10.4028/www.scientific.net/amr.47-50.467.

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The osseointegration capability of titanium dental implants is related to their chemical composition and surface roughness. In this study, the combination of grit-blasting and micro-arc oxidation had been used for producing the improved implant surfaces. The ceramic particles were projected to titanium dental implants through a nozzle at high velocity by means of compressed air to get high surface roughness. Then the surface of titanium implants was modified by micro-arc oxidation treatment. The current density, frequency and duty were 50-300 mA/cm2, 100 Hz, and 50%, respectively. A porous TiO

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Vulović, Aleksandra, Fernando Gustavo Warchomicka, and Nenad Filipović. "Finite Element Analysis of Surface Modification of Titanium Alloy Used for Hip Implant." Materials Science Forum 1016 (January 2021): 1544–48. http://dx.doi.org/10.4028/www.scientific.net/msf.1016.1544.

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Titanium and its alloys, especially Ti-6Al-4V have found application as hip implants due to their mechanical properties, excellent biocompatibility, and corrosion resistance. The use of cementless hip implants has increased over the years as it is thought that this type is more durable compared to cemented hip implants. Cementless hip implants have a porous surface that allows the bone to grow into it and form a strong bone–implant connection. The goal of this study is the use of Finite Element Method simulations to obtain information about how different types of surface topography of a TI-6Al

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Alontseva, D. L., M. B. Abilev, A. M. Zhilkashinova, et al. "Optimization of Hydroxyapatite Synthesis and Microplasma Spraying of Porous Coatings Onto Titanium Implants." Advances in Materials Science 18, no. 3 (2018): 79–94. http://dx.doi.org/10.1515/adms-2017-0043.

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AbstractThe paper presents the main results of development and optimization of the synthesis of hydroxyapatite and the application of the micro-plasma spraying technique for biocompatible coatings. The hydroxyapatite synthesis was optimized using the mathematical modelling method. Synthesized hydroxyapatite was studied by IR spectrometry and X-ray diffraction analysis for assessment of the compatibility of the chemical and phase composition to the bone tissue. The Ca/P ratio of the obtained hydroxyapatite was 1.65, which is close to that of bone tissue (1.67). To increase the adhesion strength

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Piglionico, Sofia, Julie Bousquet, Naveen Fatima, Matthieu Renaud, Pierre-Yves Collart-Dutilleul, and Philippe Bousquet. "Porous Tantalum vs. Titanium Implants: Enhanced Mineralized Matrix Formation after Stem Cells Proliferation and Differentiation." Journal of Clinical Medicine 9, no. 11 (2020): 3657. http://dx.doi.org/10.3390/jcm9113657.

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Titanium dental implants are used routinely, with surgical procedure, to replace missing teeth. Even though they lead to satisfactory results, novel developments with implant materials can still improve implant treatment outcomes. The aim of this study was to investigate the efficiency of porous tantalum (Ta) dental implants for osseointegration, in comparison to classical titanium (Ti). Mesenchymal stem cells from the dental pulp (DPSC) were incubated on Ta, smooth titanium (STi), and rough titanium (RTi) to assess their adhesion, proliferation, osteodifferentiation, and mineralized matrix pr

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Im, Yeon Min, Dong Woo Khang, and Tae Hyun Nam. "Nanostructured Titanium Biomaterials: Understanding and Applications." Materials Science Forum 654-656 (June 2010): 2053–56. http://dx.doi.org/10.4028/www.scientific.net/msf.654-656.2053.

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Nanostructured implant materials are considered as promising future biomaterials. Specifically, titanium based nanomaterial is the mostly used implant materials in orthopedic, dental and vascular surgeries. Due to the advantage of nanoscale features, treatment with nano porous and nano bump surface features have shown enhanced biocompatibilities, such as adhesion, proliferation and differentiation for bone and vascular cells. In addition, nanotoxicity issue with immune cells (macrophages) is currently paramount interest for determining subsequent tissue cellular response on implanted biomateri

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