Academic literature on the topic 'Porphyrin metabolism'

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Journal articles on the topic "Porphyrin metabolism"

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Thunell, S. "Porphyrins, porphyrin metabolism and porphyrias. I. Update." Scandinavian Journal of Clinical and Laboratory Investigation 60, no. 7 (2000): 509–40. http://dx.doi.org/10.1080/003655100448310.

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Straka, J. G., J. M. Rank, and J. R. Bloomer. "Porphyria and Porphyrin Metabolism." Annual Review of Medicine 41, no. 1 (1990): 457–69. http://dx.doi.org/10.1146/annurev.me.41.020190.002325.

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Hindmarsh, J. T. "The porphyrias: recent advances." Clinical Chemistry 32, no. 7 (1986): 1255–63. http://dx.doi.org/10.1093/clinchem/32.7.1255.

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Abstract Recent research has elucidated several of the hitherto poorly understood steps in heme synthesis. This review describes this metabolic pathway and pinpoints the enzymatic blockages in the various porphyrias. Recent advances in the understanding of the etiology of porphyria cutanea tarda are discussed, as are the abnormalities of porphyrin metabolism seen in chronic renal failure and in lead poisoning. An outline is given of the clinical and biochemical abnormalities seen in the porphyrias. Included is an algorithm to aid in the differential diagnosis of these diseases, and a brief rev
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Krivosheev, Alexander B., L. Ya Kupriyanova, and M. A. Kondratova. "DOUBLE PORPHYRIA: LITERATURE REVIEW AND ANALYSIS OF CLINICAL OBSERVATION." Russian Journal of Skin and Venereal Diseases 21, no. 2 (2018): 120–24. http://dx.doi.org/10.18821/1560-9588-2018-21-2-120-124.

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A brief review of the literature on the problem of double porphyria and analysis of its own observation is presented. For more than 10 years patient B was observed for more than 10 years with a verified diagnosis of acute intermittent porphyria, which manifested with acute pain abdominal syndrome, neurological disorders in the form of peripheral polyneuropathy and hemiparesis of lower extremities, and hypertension syndrome was also noted. The observed clinical symptoms corresponded to an acute porphyrin crisis in the manifestation and / or relapse of acute intermittent porphyria. The diagnosis
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Baytaeva, D. A., and S. S. Bessmel’tsev. "Porphyrin metabolism in secondary hepatic porphyria in patients with hereditary deficiency of glucose-6-phosphate dehydrogenase." Kazan medical journal 93, no. 3 (2012): 451–55. http://dx.doi.org/10.17816/kmj1865.

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Aim. The study the porphyrin metabolism during the development of secondary hepatic porphyria in patients with glucose-6-phosphate dehydrogenase deficiency. Methods. Examined were 148 male patients aged 5-19 years (median 12 years) with impaired activity of glucose-6-phosphate dehydrogenase in combination with β-thalassemia and without it. Qualitative and quantitative methods of examining the activity of this enzyme were used in order to verify the diagnosis. Taking into account the varying degree of glucose-6-phosphate dehydrogenase deficiency, the indices of metabolism of the enzyme and of t
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Schoenfeld, N., and R. Mamet. "Interference of ofloxacin with determination of urinary porphyrins." Clinical Chemistry 40, no. 3 (1994): 417–19. http://dx.doi.org/10.1093/clinchem/40.3.417.

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Abstract The second-generation quinolone ofloxacin interferes with the screening test of porphyrins. We observed a 20-fold increase in the porphyrin concentration measured in urine of an ofloxacin-treated patient, compared with drug-free normal urine. Two other fluorinated 4-quinolones tested, norfloxacin and ciprofloxacin, had a less marked effect (a twofold increase), whereas the first-generation quinolone, nalidixic acid, did not affect the measured porphyrin concentration at all. The interference is probably due to the overlap in the emission fluorescence spectra of ofloxacin and urinary p
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Paw, Barry H., Yvette Y. Yien, Raymond F. Robledo, et al. "Tmem14c Plays An Essential Role In Mitochondrial Heme Metabolism." Blood 122, no. 21 (2013): 427. http://dx.doi.org/10.1182/blood.v122.21.427.427.

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Abstract Red cells synthesize large amounts of heme during terminal differentiation. Central to this process is the transport and trafficking of heme synthesis intermediates within the cell. Despite the importance of transport during heme synthesis, the molecules involved in this process are largely unknown. In a screen for genes that are upregulated during erythroid terminal differentiation, we identified Tmem14c, a predicted multi-pass transmembrane protein as an essential component of the porphyrin metabolism pathway. Here, we report that Tmem14c facilitates the synthesis of mitochondrial p
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S. Thunell, P. Harper, A. Brock, N. "Porphyrins, porphyrin metabolism and porphyrias. II. Diagnosis and monitoring in the acute porphyrias." Scandinavian Journal of Clinical and Laboratory Investigation 60, no. 7 (2000): 541–60. http://dx.doi.org/10.1080/003655100448329.

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Baytaeva, D. A., та S. S. Bessmeltsev. "The metabolitic role of the iron porphyrin complex in the development of anemic syndrome in patients with minor form of β-thalassemia". Kazan medical journal 93, № 1 (2012): 7–11. http://dx.doi.org/10.17816/kmj2135.

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Aim. To determine the significance of the main indicators of metabolism of porphyrins and markers of iron metabolism in the development of anemic syndrome during β-thalassemia minor. Methods. Examined were 58 patients with β-thalassemia minor with a concomitant deficiency of the enzyme glucose-6-phosphate dehydrogenase and 150 patients β-thalassemia minor without the concomitant enzymopathy. Hemoglobin electrophoresis was used to verify the diagnosis of β-thalassemia. Evaluated were the main indicators of porphyrin metabolism in the erythrocytes and urine in comparison with the reserve pool of
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Harper, S. Thunell, P. "Porphyrins, porphyrin metabolism, porphyrias. III. Diagnosis, care and monitoring in porphyria cutanea tarda - suggestions for a handling programme." Scandinavian Journal of Clinical and Laboratory Investigation 60, no. 7 (2000): 561–80. http://dx.doi.org/10.1080/003655100448338.

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Dissertations / Theses on the topic "Porphyrin metabolism"

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Luo, Jin-Li. "Porphyrin metabolism in porphyria cutanea tarda." Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315308.

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Guo, Rong. "Porphyrin metabolism in congenital erythropoietic porphyria." Thesis, Open University, 1992. http://oro.open.ac.uk/57392/.

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Meso-hydroxyuroporphyrin I, B-hydroxypropionic acid uroporphyrin I, hydroxyacetic acid uroporphyrin I and peroxyacetic acid uroporphyrin I have been isolated from the urine and plasma of patients with congenital erythropoietic porphyria (CEP) by high-performance liquid chromatography and characterized by liquid secondary ion mass spectrometry and chemical properties. The physico-chemical properties of these compounds have been studied. The hydroxy- and peroxyacetic acid- uroporphyrin I derivatives are the true metabolites of uroporphyrinogen I in vivo and their presence in urine and plasma is
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Cai, Hong. "Free radicals in porphyrin metabolism and photodynamic therapy of cancer." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392344.

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Lôvo, Luciana de Paula Baggini. "Uso de manganêsporfirinas na oxidação de hidrocarbonetos e no metabolismo de drogas." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-17012007-092631/.

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A imobilização da MeP em suportes inorgânicos permite isolar o sítio de reação prevenindo a dimerização e/ou auto-destruição oxidativa da mesma, constituindo-se num catalisador biomimético. Neste projeto foi objetivo avaliar o comportamento biomimético de manganês porfirinas, comparando sistemas imobilizadas de diferentes maneiras em sílica funcionalizada em processos de oxigenação do cicloocteno ecicloexano, incluindo metabolismo de um fármaco. A primeira etapa do projeto consistiu na obtenção dos sistemas catalíticos contendo metaloporfirinas imobilizadas em sílicas modificadas. Para iss
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Homedan, Chadi. "La fonction mitochondriale dans un modèle murin de Porphyrie Aiguë Intermittente (PAI)." Thesis, Angers, 2015. http://www.theses.fr/2015ANGE0077/document.

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Les déficits héréditaires de la synthèse de l’hème sont à l’origine de pathologies métaboliques appelées porphyries. La plus sévère est une porphyrie hépatique, la porphyrie aiguë intermittente (PAI). Des liens métaboliques étroits existent entre la synthèse de l’hème et la mitochondrie. L’objectif de ce travail était d’étudier l’impact de la crise aiguë de PAI sur le fonctionnement énergétique mitochondrial. Nous avons montré, dans un modèle murin déficitaire en hydroxymethylbilane synthase (HMBS) mimant biologiquement la crise de PAI, un dysfonctionnement énergétique mitochondrial. L’activit
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Schweikert, Katja, and n/a. "The functional biology of Porphyra sp. in New Zealand." University of Otago. Department of Botany, 2007. http://adt.otago.ac.nz./public/adt-NZDU20080910.114121.

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The intertidal red algal genus Porphyra is found on rocky shores worldwide. In the Northern Hemisphere the genus is well studied but there is a paucity of data on southern hemisphere Porphyra and even less on New Zealand Porphyra. The species� taxonomy has been undergoing revision since the late 1990�s, when it was discovered that the main species P. columbina and P. lilliputana reported for New Zealand were a combination of several endemic species. These species are found from the low to the high intertidal watermark; hence they are exposed to fluctuating stresses such as desiccation, tempera
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Inada, Natalia Mayumi. "Ação fotodinamica de meso-porfirinas sobre função mitocondrial e viabilidade de celulas LNCaP." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/308197.

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Orientador: Anibal Eugenio Vercesi<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-06T17:46:44Z (GMT). No. of bitstreams: 1 Inada_NataliaMayumi_D.pdf: 2015643 bytes, checksum: 46616bc6e9a94ab575e17060c6ed0645 (MD5) Previous issue date: 2006<br>Resumo: A ação das meso-porfirinas catiônica Fe(III)TMPyP e aniônica Fe(III)TPPS4 sobre a função mitocondrial e viabilidade de células de tumor de próstata LNCaP foi investigada. O tratamento das suspensões mitocondriais com 1 µM de Fe(III)TMPyP por 2 minutos e 45 segundos no
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Santos, Maria Leonor Veríssimo dos. "A transcriptomic approach to the metabolism of porphyrin-like pigments in a marine Polychaeta (Eulalia sp.)." Master's thesis, 2020. http://hdl.handle.net/10362/114346.

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The last decade witnessed a growing interest on marine natural pigments for biotechnological and biomedical applications. One of the most abundant naturally occurring pigments are the tetrapyrroles which are prized targets due to their photodynamic properties. Their most notorious representatives are porphyrins. Animal porphyrins result from the breakdown of heme and are known as bile pigments, the best known of which are biliverdin and bilirubin. Because of their unique chemical structure, porphyrins can have several applications such as photosensitizers in photodynamic therapy as w
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Becker, David Morris. "Studies on the metabolism of drug-induced porphyria." Thesis, 2015. http://hdl.handle.net/10539/16181.

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Giles, Kaleigh. "Insight into the Functionality of an Unusual Glycoside Hydrolase from Family 50." Thesis, 2014. http://hdl.handle.net/1828/5832.

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Agarose and porphyran are related galactans that are only found within red marine algae. As such, marine microorganisms have adapted to using these polysaccharides as carbon sources through the acquisition of unique Carbohydrate Active enZymes (CAZymes). A recent metagenome study of the microbiomes from a Japanese human population identified putative CAZymes in several bacterial species, including Bacteroides plebeius that have significant amino acid sequence similarity with those from marine bacteria. Analysis of one potential CAZyme from B. plebeius (BpGH50) is described here. While displayi
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Books on the topic "Porphyrin metabolism"

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Moore, Michael R., Kenneth E. L. McColl, Claude Rimington, and Abraham Goldberg. Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2.

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International Congress on Porphyrins and Porphyrias (2nd 1985 Paris, France). Porphyrins and porphyrias =: Porphyrines et porphyries : proceedings of the Second International Congress on Porphyrins and Porphyrias held in Paris (France), 19-22 June, 1985. J. Libbey, 1986.

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International, Congress on Porphyrins and Porphyrias (2nd 1985 Paris France). Porphyrins and porphyrias: Proceedings of the Second International Congress on Porphyrins and Porphyrias held in Paris (France) 19-22 June, 1985 = Porphyrines et porphyries. Editions INSERM, 1986.

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The chemistry and biochemistry of N-substituted porphyrins. VCH Publishers, 1987.

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Parker, James N., and Philip M. Parker. Porphyria: A bibliography and dictionary for physicians, patients, and genome researchers [to Internet references]. ICON Health Publications, 2007.

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R, Moore Michael, and Wintrobe Maxwell Myer 1901-, eds. Disorders of porphyrin metabolism. Plenum Medical Book Co., 1987.

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A, Goldberg, K. E. L. McColl, and M. R. Moore. Disorders of Porphyrin Metabolism. Springer, 2012.

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Wolstenholme, G. E. W., and Elaine C. P. Millar. Porphyrin Biosynthesis and Metabolism. Wiley & Sons, Incorporated, John, 2009.

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Goldberg, Sir Abraham. Disorders of Porphyrin Metabolism. Springer, 2012.

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Webb, S. M., and R. A. Hoffman. Harderian Glands: Porphyrin Metabolism, Behavioral, and Endocrine Effects. Springer, 1992.

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Book chapters on the topic "Porphyrin metabolism"

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Nagaraj, Viswanathan Arun, Pundi Narasimhan Rangarajan, and Govindarajan Padmanaban. "Porphyrin Metabolism." In Encyclopedia of Malaria. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8757-9_4-1.

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Moore, Michael R., Kenneth E. L. McColl, Claude Rimington, and Abraham Goldberg. "Porphyrins in Diseases Other than the Porphyrias." In Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_10.

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Bloomer, Joseph R., and Hiba Risheg. "Bilirubin and Porphyrin Metabolism." In Atlas of the Liver. Current Medicine Group, 2004. http://dx.doi.org/10.1007/978-1-4615-6502-4_1.

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Doss, M. O. "Alcohol and Porphyrin Metabolism." In Alcohol Related Diseases in Gastroenterology. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70048-4_13.

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Hahn, Martin, and Herbert L. Bonkovsky. "Disorders of Porphyrin Metabolism." In Diseases of the Liver and Bile Ducts. Humana Press, 1998. http://dx.doi.org/10.1007/978-1-4612-1808-1_19.

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Moore, Michael R., Kenneth E. L. McColl, Claude Rimington, and Abraham Goldberg. "Congenital Porphyria." In Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_9.

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Moore, Michael R., Kenneth E. L. McColl, Claude Rimington, and Abraham Goldberg. "Porphyria in Animals." In Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_11.

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Moore, Michael R., Kenneth E. L. Mccoll, Claude Rimington, and Abraham Goldberg. "Cutaneous Hepatic Porphyria." In Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_7.

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Rimington, Claude. "Perspective." In Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_12.

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Moore, Michael R., Kenneth E. L. McColl, Claude Rimington, and Abraham Goldberg. "The History, Classification, and Incidence of the Porphyrias." In Disorders of Porphyrin Metabolism. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_1.

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Conference papers on the topic "Porphyrin metabolism"

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Dai, Jing, Yunjing Luo, Yuanbin She, and Rugang Zhong. "Notice of Retraction: Metabolism of Phenanthrene in Peroxynitrite/Fe(III) Porphyrin System by HPLC-MS." In 2011 5th International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2011. http://dx.doi.org/10.1109/icbbe.2011.5780236.

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