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Dissertations / Theses on the topic 'Porphyromonas gingivalis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Loomer, Peter Michael. "The direct effects of Porphyromonas gingivalis 2561 on bone formation and mineral resorption in vitro." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ27685.pdf.

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2

Meuric, Vincent. "Virulence de Porphyromonas gingivalis." Rennes 1, 2008. http://www.theses.fr/2008REN1B197.

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"Porphyromonas gingivalis est une bactérie anaérobie stricte responsable des maladies parodontales. La respiration et la régulation des gènes de virulence restent inconnues. Ce travail explore la chaîne respiratoire et montre l'aérotolérance de la bactérie. Les résultats affirment la capacité de transmission aéroportée et inter individus par des mécanismes activant des gènes de résistance au stress oxydatif tel que "tpx" sous la dépendance d'OsyR régulateur transcriptionnel. Après une analyse de la littérature sur les principaux gènes de virulence, hémagglutinines et gingipaïnes, les études ex

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3

Hoppe, Tatjana [Verfasser]. "Maligne Transformation gingivaler Epithelzellen durch Porphyromonas gingivalis / Tatjana Hoppe." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/1140525883/34.

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4

Lobos, Matthei Ignacio Felipe. "Regulación de survivina en células epiteliales gingivales infectadas por Porphyromonas gingivalis." Tesis, Universidad de Chile, 2014. http://www.repositorio.uchile.cl/handle/2250/117229.

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Memoria para optar el título de Bioquímico<br>La periodontitis crónica es una enfermedad de etiología infecciosa, caracterizada por la respuesta inflamatoria e inmune exacerbada por parte del hospedero que produce la destrucción de tejidos de soporte del diente. Actualmente, se postula que para el establecimiento de esta patología se produce una sucesión ecológica desde una comunidad microbiana asociada a salud hacia una asociada a enfermedad periodontal. En esta sucesión es imprescindible la presencia de ciertos patógenos que faciliten el remodelamiento de la microbiota oral y la progresión h

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5

Bugueño, Valdebenito Isaac Maximiliano. "Caracterización de aislados clínicos de Porphyromonas gingivalis y su efecto en la viabilidad de células epiteliales gingivales." Tesis, Universidad de Chile, 2014. http://www.repositorio.uchile.cl/handle/2250/130110.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>La periodontitis es una enfermedad infecciosa multifactorial, caracterizada por una respuesta inflamatoria exacerbada que produce la destrucción de las estructuras que dan soporte al diente, incluyendo la encía, el ligamento periodontal, el cemento radicular y el hueso alveolar. Para la iniciación de las periodontitis, se requiere la presencia de una comunidad bacteriana subgingival compleja en la cual coexisten diversos géneros y especies microbianas. Dentro de las especies del complejo rojo de Socransky qu

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6

Maley, Janette. "Genetic studies on Porphyromonas gingivalis W83." Thesis, University of Leicester, 1994. http://hdl.handle.net/2381/35395.

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Until recently molecular biological approaches to the study of putative virulence factors of the oral pathogen Porphyromonas gingivalis were limited. This was due to the absence of a genetic system which could facilitate the production of isogenic mutant derivatives. Among the many components produced, the capsule is believed to be of particular importance in the pathogenicity of P. gingivalis. In order to identify mutants lacking capsular polysaccharide, purified capsular material from P. gingivalis W83 was used to generate capsule-specific antisera. However, these antisera contained antibodi

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7

Xie, Hua. "Regulation of fimbrillin expression in Porphyromonas gingivalis." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/6392.

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8

Rodrigues, Richelle Soares. "PrevalÃncia de Porphyromonas gingivalis, genÃtipo fima II de Porphyromonas gingivalis e Aggregatibacter actinomycetemcomitans em indivÃduos com periodontite agressiva generalizada." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11486.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>Porphyromonas gingivalis e Aggregatibacter actinomycetemcomitans sÃo periodontopatÃgenos associados Ã periodontite agressiva. A fÃmbria, uma estrutura relacionada Ã adesÃo e Ã invasÃo de cÃlulas, Ã um dos principais fatores de virulÃncia de P. gingivalis. Baseado na sequÃncia de nucleotÃdeos, seis genÃtipos(fimA) que codificam a fÃmbria principal dessas bactÃrias foram identificados, sendo o fimA II mais comumente relacionado Ã destruiÃÃo periodontal. O objetivo dest

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9

Rodrigues, Richelle Soares. "Prevalência de Porphyromonas gingivalis, genótipo fima II de Porphyromonas gingivalis e Aggregatibacter actinomycetemcomitans em indivíduos com periodontite agressiva generalizada." reponame:Repositório Institucional da UFC, 2014. http://www.repositorio.ufc.br/handle/riufc/7904.

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RODRIGUES, Richelle Soares. Prevalência de Porphyromonas gingivalis, genótipo fima II de Porphyromonas gingivalis e Aggregatibacter actinomycetemcomitans em indivíduos com periodontite agressiva generalizada. 2014. 44 f. Dissertação (Mestrado em Odontologia) - Universidade Federal do Ceará. Faculdade de Farmácia, Odontologia e Enfermagem, Fortaleza, 2014.<br>Submitted by denise santos (denise.santos@ufc.br) on 2014-04-04T13:13:32Z No. of bitstreams: 1 2014_dis_rsrodrigues.pdf: 909297 bytes, checksum: 47ad16e66062d057016963a13334a1f2 (MD5)<br>Approved for entry into archive by denise santos(den

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10

Herrera, Bustamante Sergio Humberto. "Variabilidad del LPS de Porphyromonas gingivalis y Porphyromonas endodontalis en dientes con periodontitis apical asintomática." Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/137646.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>La Periodontitis Apical Asintomática (PAA) corresponde a una patología periapical de origen infeccioso que se caracteriza por la respuesta negativa a los tests de sensibilidad pulpar del diente afectado y por presentar, al examen radiográfico, un área radiolúcida peri y/o pararadicular. Histológicamente se puede clasificar como quiste radicular inflamatorio (QRI) o granuloma periapical (GP). Las comunidades microbianas asociadas a la PAA se caracterizan por infectar el sistema de canales radiculares (SCR) de

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11

Houalet-Jeanne, Sylvie. "Etude in-vitro de l'internalisation de Porphyromonas gingivalis dans la cellule pariétale gingivale." Rennes 1, 2001. http://www.theses.fr/2001REN1B085.

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Porphyromonas gingivalis (P. Gingivalis) est décrit comme l'un des pathogènes majeurs de la maladie parodontale. Il est également impliqué dans l'étiologie de pathologies systémiques. A ce jour, les mécanismes précis de son pouvoir de virulence gardent d'importantes zones d'ombre. Le travail présenté ici, s'applique à confirmer le potentiel invasif de la bactérie face à la cellule hôte, et à préciser son devenir dans la cellule épithéliale. L'utilisation de différents marqueurs sur un modèle in vitro, nous a permis de détecter P. Gingivalis au sein de cellules épithéliales de lignée KB en Micr

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12

Al-Qutub, Montaser Nazmi. "Lipopolysaccharide lipid A structural heterogeneity of Porphyromonas gingivalis /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/6383.

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13

Yuan, Lihui. "Quorum sensing regulated gene expression in Porphyromonas gingivalis." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0010043.

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Thesis (Ph.D.)--University of Florida, 2005.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 134 pages. Includes Vita. Includes bibliographical references.

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14

Ally, Nafisa. "The specificity of proteinase-adhesins from Porphyromonas gingivalis." Monash University, Dept. of Biochemistry and Molecular Biology, 2003. http://arrow.monash.edu.au/hdl/1959.1/9477.

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15

Fawell, Stuart Colin. "Polymorphism in the rag locus of porphyromonas gingivalis." Thesis, Queen Mary, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412704.

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16

Muzahim, Kzar Ryam. "Porphyromonas gingivalis inducerar frisättningav IL-8 från monocyter." Thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-37667.

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17

Bhatti, Manpreet. "A study of the photolysis of Porphyromonas gingivalis." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311934.

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18

Abusleme, Ramos Loreto Andrea. "Genotipificación de porphyromonas gingivalis en pacientes con periodontitis." Tesis, Universidad de Chile, 2009. http://repositorio.uchile.cl/handle/2250/135077.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Autor no autoriza el acceso a texto completo de su documento<br>La periodontitis es un tipo de enfermedad periodontal que afecta a los tejidos de inserción de las piezas dentarias. En la actualidad, entre los agentes etiológicos que tienen mayor participación en la génesis de las periodontitis, destacan A. actinomycetemcomitans y las bacterias pertenecientes al complejo rojo. P. gingivalis presenta diversos factores de virulencia, como su capacidad de adherencia a los tejidos periodon

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19

Schlenker, Courtney. "The Characterization of PG0228 in Porphyromonas gingivalis W83." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/219.

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Periodontitis affects 10 to 15 percent of most adult populations and can contribute to numerous systemic diseases. Porphyromonas gingivalis, a gram-negative anaerobic bacterium, is a recognized prime causative agent in periodontitis. Studies have shown a number of small non-coding RNAs (sRNAs) have been related to bacterial virulence. Many of these sRNAs require the facilitation of the bacterial Sm-like protein, Hfq, for optimum function. Hfq is a RNA chaperone involved in RNA stability, sRNA function, and polyadenylation. Mutants lacking in Hfq often show pleiotropic phenotypes, although the

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20

Dwyer, Holly. "Characterization of putative Porphyromonas gingivalis RNA-binding proteins." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3550.

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Porphyromonas gingivalis (P. gingivalis) is a gram-negative, anaerobic bacterium recognized as a major player in progression of periodontal disease. P. gingivalis survives in the oral cavity while being exposed to dynamic environmental conditions such as pH, temperature, nutrient availability and host immune responses such as oxygen tension and nitrosative stress. Survival and pathogenesis of P. gingivalis in the oral cavity require mechanisms to regulate gene expression in response to the extracellular signals. Little is known about the regulatory mechanisms of P. gingivalis in the oral cavit

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21

Singh, Umadatt. "The adherence properties of Bacteroides gingivalis." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/31013.

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A Bacteroides gingivalis adhesin mediating attachment to red blood cells and buccal epithelial cells was isolated, cloned and characterized. The isolation procedure involved gentle stirring of the cells followed by ammonium sulphate precipitation, ion-exchange and gel chromatography. The native molecule had a Mr in excess of 10⁶ kDa and was made up of subunits with an Mr of 43 kDa. Antisera raised to the adhesin and its subunits reacted with antigens on the surface of B. gingivalis cells. No reaction with fimbriae was seen. The IgG fractions from these antisera inhibited the adherence of B. gi

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22

Shelburne, C. E. "Stress-induced P. gingivalis gene expression in periodontal disease." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269172.

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23

Díaz, Patricia I. "Studies on the oxidative stress response of porphyromonas gingivalis : a thesis submitted in fulfillment of the requirements for admission to the degree of Doctor of Philosophy /." Title page, summary and table of contents only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phd5426.pdf.

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24

Fariña, Espinosa Valeska Gissel. "Respuesta inmune humoral y endotexemia en infección endodóntica con Porphyromonas endodontalis y Porphyromonas gingivalis en periodontitis apical asintomática." Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/137589.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Introducción: La periodontitis apical asintomática (PAA) corresponde a una patología de etiología polimicrobiana que resulta en la destrucción del periodonto apical debido a una reacción inflamatoria crónica. Existe evidencia creciente de que infecciones crónicas en la cavidad oral pueden producir diseminación de productos bacterianos e inflamatorios a la circulación general y activación del sistema inmune con posible inducción de efectos sistémicos adversos. El potencial efecto sistémico asociado a PAA y en

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25

Palm, Eleonor. "Inflammatory responses of gingival fibroblasts in the interaction with the periodontal pathogen Porphyromonas gingivalis." Doctoral thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-38660.

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26

Bainbridge, Brian W. "Generation and function of Porphyromonas gingivalis lipid A heterogeneity /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/6394.

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27

Zark, S. "Mechanisms of immunomodulation by the periodontal pathogen Porphyromonas gingivalis." Thesis, Queen's University Belfast, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546428.

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28

Belfield, Louise Alicia. "Interactions between porphyromonas gingivalis and macrophages in oral pathology." Thesis, University of Plymouth, 2013. http://hdl.handle.net/10026.1/1611.

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Macrophages play a fundamental role in driving both inflammatory and immunosuppressive conditions of the oral mucosa. Periodontitis, a chronic inflammatory condition affecting the supporting structures of the teeth, is widely prevalent, affecting a large proportion of the global population, and has been linked to the development of systemic inflammatory diseases. Oral squamous cell carcinoma (OSCC) is placed sixth in the WHO rankings of cancer incidence worldwide, and despite continuing research into underlying mechanisms, incidence is on the rise. Aberrant macrophage function has been implica

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Montenegro, Chipana Alex. "Actividad antibacteriana de Caesalpinia spinosa (tara) sobre Porphyromonas gingivalis." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/3723.

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La periodontitis es una enfermedad de etiología infecciosa que presenta como síntomas el sangrado e inflamación de encías, movilidad dentaria, recesiones gingivales, en las que diversas enfermedades sistémicas favorecen su progresión. Uno de estos agentes más importantes es Porphyromonas gingivalis, especie bacteriana anaeróbica estricta, Gram negativo. A su vez, el uso de antibióticos sistémicos está indicado sólo en ciertos tipos de periodontitis, y no siempre el tratamiento es exitoso. Hoy en día, tanto en medicina general como odontológica, se está investigando nuevas alternativas de trata

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30

Sai, Suhasini Yanamandra. "Role of Extracytoplasmic Function Sigma Factors in Porphyromonas gingivalis." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/488.

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Porphyromonas gingivalis is a major etiological agent that is responsible for the cause and progression of periodontal diseases. The bacterium is exposed to various environmental conditions and oxidative stress conditions while it is in the oral cavity. So, P. gingivalis should have an efficient regulatory system in order to adjust and survive in the oral cavity. But little is known about the regulatory mechanisms that help the bacteria to survive in the oral cavity. So, it is essential to understand and characterize these regulatory mechanisms. The response and adaptation of P. gingivalis to

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31

Warren, Cheyanne. "The Response of HN4 Cells to Porphyromonas gingivalis DNA." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1572.

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Periodontal disease is one of the most common human diseases. Bacteria trigger the onset and progression of the disease and among them Porphyromonas gingivalis has been demonstrated to be a major etiologic agent. Although the interaction of the bacterium with the host is of major importance for the understanding of the disease mechanisms, both the host as well as the pathogen components involved in the interaction remain poorly understood. One of the bacterial components capable of eliciting a host response is unmethylated CpG DNA motifs found in bacteria. Thus, the first aim was to determine

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Paranjape, Anuya R. "Investigating the transcriptional regulation by OxyR in Porphyromonas gingivalis." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/413.

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Periodontal diseases are bacterially induced, inflammatory diseases which are responsible for loss of alveolar bone and connective tissue supporting the teeth which results in loss of teeth. Gram negative anaerobic bacteria are highly associated with these diseases. One of them is Porphyromonas gingivalis belonging to the phylum Bacteroidetes. Infection by P. gingivalis is recurrent after physical removal of the bacteria from the oral cavity and even after antibiotic treatment as development of resistance is not rare. Hence complete understanding the biology of this bacterium is of significanc

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33

Belvin, Benjamin. "HcpR of Porphyromonas gingivalis utilizes heme to bind NO." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/639.

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The obligate anaerobe Porphyromonas gingivalis is the etiological agent responsible for periodontal disease. It must withstand high levels of reactive nitrogen species in the oral cavity generated by the host and other oral flora. The mechanisms allowing for protection against such stress remain poorly understand. HcpR is an FNR-CRP family regulator that has been implicated in regulation of the nitrosative stress response. In this study we characterize the biochemical properties of HcpR. It is a homo-dimer that is composed of 3 domains – a heme-binding domain, dimerization helix, and a DNA-bin

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Rostami, Soheil. "Characterization of a putative TonB deficient Porphyromonas gingivalis mutant." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3492.

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Porphorymonas gingivalis is one of the major bacterial pathogens responsible for the initiation and progression of periodontal disease. The bacterium requires hemin uptake for its growth and has developed sophisticated mechanisms to extract hemin from hemin containing proteins in the oral cavity. Hemin first binds to receptors on the surface of P. gingivalis and is then taken up in an energy dependent manner. TonB is an inner membrane bound protein that spans the periplasm and is believed to be involved in the passage of hemin through the double membrane of P. gingivalis. However, the TonB pro

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35

Wu, Fan [Verfasser]. "Porphyromonas gingivalis induces PD-L1 upregulation in prostate cancer cells : impact of the periodontopathogenic bacterium Porphyromonas gingivalis on prostate cancer cells / Fan Wu." Gießen : Universitätsbibliothek, 2021. http://d-nb.info/1233036661/34.

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Meléndez, Stefony Martina Cassandra. "Tipificación de Aggregatibacter actinomycetemcomitans y Porphyromonas gingivalis en pacientes afectados con periodontitis." Tesis, Universidad de Chile, 2013. http://www.repositorio.uchile.cl/handle/2250/117483.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Introducción: Las periodontitis son un conjunto de enfermedades infecciosas, caracterizadas por la destrucción de los tejidos de inserción de los dientes, cuya causa es el biofilm subgingival. Porphyromonas gingivalisy Aggregatibacter actinomycetemcomitansson bacterias periodonto-patógenas del biofilm subgingival que han sido ampliamente asociadas al inicio, progresión y severidad de la enfermedad.Sobre la base de la cápsula extracelular de P. gingivalis y del Opolisacárido del LPS de A. actinomycetemcomit

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Blasi, Beriain Ignacio. "Porphyromonas gingivalis LPS stimulates autophagy using a TLR mediated pathway." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/461098.

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Resum: Porphyromonas gingivalis often subverts host cell autophagic processes for its own survival. Our previous studies document the association of the cargo sorting protein, melanoregulin (MREG), with its binding partner, the autophagic protein, microtubule-associated protein 1 light chain 3 (LC3) in macrophages incubated with P. gingivalis (strain 33277). Differences in the lipid A moiety of lipopolysaccharide (LPS) affect the virulence of P. gingivalis; penta-acylated LPS1690 is a weak Toll-like receptor 4 agonist compared with Escherichia coli LPS, whereas tetra-acylated LPS1435/1449 act

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Geraldo, Barbara Maria Corrêa. "Efeito antimicrobiano e imunomodulador de Lactobacillus reuteri em cultura de osteoblastos e Galleria mellonella desafiados por Porphyromonas gingivalis /." São José dos Campos, 2017. http://hdl.handle.net/11449/151089.

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Orientador: Ana Lia Anbinder<br>Banca: Maria Aparecida Neves Jardini<br>Banca: Débora Pallos<br>Resumo: Os tratamentos mais usados para periodontite são a raspagem e aplainamento radicular, tratamento não cirúrgico, associado ou não ao uso de antimicrobianos. No entanto, novas terapias têm sido testadas com foco na modulação da resposta do hospedeiro. Alguns micro-organismos têm efeitos benéficos na saúde dos seres humanos, pois produzem efeitos antimicrobianos e anti-inflamatórios, os chamados probióticos. O presente trabalho avaliou o efeito antimicrobiano de Lactobacillus reuteri sobre Porp

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39

Suwannakul, Suttipalin. "Isolation of porphyromonas gingivalis that differs in epithelial cells invasion." Thesis, University of Sheffield, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527233.

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40

Rigg, Gordon P. "Molecular characterisation of PgaA, an antigen from periodontopathogen Porphyromonas gingivalis." Thesis, University of Leicester, 1995. http://hdl.handle.net/2381/35411.

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Molecular cloning techniques were used to investigate antigenic determinants of periodontopathogen P. gingivalis in an attempt to begin to explore the cell surface of this organism. A genomic library generated in Escherichia coli was probed with polyclonal antiserum specific for P. gingivalis whole cells. Clone pGPR1, which contained a 307 bp fragment of P. gingivalis DNA sequence, was found to react with both polyclonal antiserum and a monoclonal antibody (mAb) specific for the trypsin-like protease of this organism (Brick190). This fragment was used to probe a second P. gingivalis genomic li

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41

Montgomery, Anna Barbara Kay. "Porphyromonas gingivalis peptidylarginine deiminase in the aetiology of rheumatoid arthritis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:b98d61c0-9863-4b20-a352-3737010fe8f1.

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Anti-citrullinated protein antibodies (ACPA) are the main autoantibodies in rheumatoid arthritis (RA). Citrullination is the conversion of arginine to citrulline by peptidylarginine deiminase (PAD) enzymes. Periodontitis (PD) is a risk factor for RA, and there is evidence this may be due to citrullination by the unique prokaryotic PAD enzyme expressed by PD pathogen Porphyromonas gingivalis (PPAD). The aim of this work was to characterise PPAD, and investigate its potential role in the aetiology of RA. The 3D crystal structure of PPAD was solved, and functional residues identified. The catalyt

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42

Igboin, Christina. "Comparative genomic analysis and host-pathogen interactions of porphyromonas gingivalis." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1197405913.

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43

He, Jia. "Identification and Characterization of Metal Uptake Loci in Porphyromonas gingivalis." Available to VCU users at :, 2007. http://hdl.handle.net/10156/1263.

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Mirpanah, Jacob. "Biochemical Analysis of Putative RNA-Binding Proteins in Porphyromonas gingivalis." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5379.

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BIOCHEMICAL ANALYSIS OF PUTATIVE RNA-BINDING PROTEINS IN PORPHYROMONAS GINGIVALIS By Jacob Mirpanah Bachelor of Arts in Biology, University of Virginia, 2015 A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Physiology and Biophysics at Virginia Commonwealth University Virginia Commonwealth University, 2018 Major Director: Janina P. Lewis, Ph.D., Philips Institute for Oral Health Research RNA-Binding Proteins (RBPs) play important regulatory roles in countless cellular processes. Often via the induction of a structural change in RNA’s second

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Rojas, Celis Ana Victoria. "El Antígeno O de Porphyromonas gingivalis participa en la modulación de los niveles de Interleuquina-8 y de la migración en células epiteliales gingivales." Tesis, Universidad de Chile, 2018. http://repositorio.uchile.cl/handle/2250/170366.

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Memoria para optar al título de Bioquímico<br>La periodontitis es una enfermedad inflamatoria crónica de las estructuras que soportan las piezas dentales, la cual está asociada a un proceso infeccioso causado por un cambio en la ecología local de la biopelícula bacteriana oral. Un 90% de la población chilena presenta signos clínicos de esta patología. Porphyromonas gingivalis (P. gingivalis) se ha propuesto como un agente etiológico clave en la periodontitis. En nuestro laboratorio, se obtuvieron aislados clínicos de P. gingivalis provenientes de individuos sanos, en los que se vio ausencia de

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Herath, Mudiyanselage Thanuja Darshani Kumari Herath. "A systems biological study on heterogeneous Porphyromonas gingivalis lipopolysaccharides: human gingivalfibroblasts interaction : molecular mechanisms and implications inperiodontal pathogenesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50162615.

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Porphyromonas gingivalis is a keystone periodontopathogen and its lipopolysacharide (LPS) is strongly associated with periodontal disease. A long-standing controversy occurs on the role of P. gingivalis LPS in induction of innate host response in different cell types. It has recently been found that P. gingivalis LPS displays remarkable heterogeneity with both tetra- (LPS1435/1449) and penta-acylated (LPS1690) lipid A structures. However, the potential effects of heterogeneous structures of P. gingivalis LPS on modulating host innate responses in human gingival fibrobalsts (HGFs) - the most a

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Celis, Sersen Andrés Osvaldo. "Presencia de porphyromonas gingivalis, Genotipos fimA-I, II, III y IV, en un grupo de escolares chilenos de 4 a 8 años de edad." Tesis, Universidad de Chile, 2012. http://www.repositorio.uchile.cl/handle/2250/112097.

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Trabajo de Investigación Requisito para optar al Título de Cirujano Dentista<br>Autor no autoriza el acceso a texto completo de su tesis en el Portal de Tesis Electrónicas<br>INTRODUCCIÓN: Especies bacterianas anaeróbicas potencialmente patogénicas constituyen un porcentaje significativo de la microbiota normal de la cavidad bucal y hoy se sabe que su capacidad de colonizar y sobrevivir durante la niñez temprana, depende de las condiciones medioambientales que ofrezca el hospedero. Sin embargo, se desconoce la edad en que estas especies bacterianas comienzan a colonizar la cavidad bucal

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Burgess, Nicola. "Quorum sensing and regulation of virulence gene expression in Porphyromonas gingivalis." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394845.

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Maietta, Nathan. "Effect of pH on the transcriptional profile of Porphyromonas gingivalis W83." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2222.

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Porphyromonas gingivalis, a gram-negative, anaerobic bacterium, is widely recognized as a causative agent for periodontal disease. Despite sequencing of the complete genome, no research exists examining gene regulation response in P. gingivalis to shifts in pH. Previous studies have shown that P. gingivalis is capable of surviving in the variety of micro- environmental niches found within the oral cavity, including basic and acidic pH conditions. However, the underlying mechanisms of this survival are not well understood. This study examined P. gingivalis by comparing bacteria shocked at three

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Singh, Amrita. "ROLE OF CAPSULE IN THE INTERACTION OF PORPHYROMONAS GINGIVALIS WITH HOST." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/140.

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Periodontal disease is a chronic oral disease that is triggered by bacteria. One of these bacteria is Porphyromonas gingivalis. Some strains of P. gingivalis produce capsule, however, so far the role of capsule in the interactions with host cells in P. gingivalis is not well understood. Here, we investigated the contribution of capsule to triggering host response as well as its protective role on bacterial internalization by host cells with subsequent killing. qRT-PCR analysis showed more upregulation of expression of various groups of genes in macrophages challenged with the non-capsulated st

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