Relevant bibliographies by topics / Portosystemic

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Portosystemic'

Author: Grafiati
Published: 19 February 2023

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Journal articles on the topic "Portosystemic"

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Conn, Harold O., Martin Rössle, Lewis Levy, and Franz X. Glocker. "Portosystemic myelopathy: Spastic paraparesis after portosystemic shunting." Scandinavian Journal of Gastroenterology 41, no. 5 (January 2006): 619–25. http://dx.doi.org/10.1080/00365520500318932.

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Uflacker, R., A. de O. Silva, L. A. d'Albuquerque, R. L. Piske, and G. S. Mourão. "Chronic portosystemic encephalopathy: embolization of portosystemic shunts." Radiology 165, no. 3 (December 1987): 721–25. http://dx.doi.org/10.1148/radiology.165.3.3685350.

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Leite, Andréa Farias de Melo, Américo Mota Jr., Francisco Abaeté Chagas-Neto, Sara Reis Teixeira, Jorge Elias Junior, and Valdair Francisco Muglia. "Acquired portosystemic collaterals: anatomy and imaging." Radiologia Brasileira 49, no. 4 (August 2016): 251–56. http://dx.doi.org/10.1590/0100-3984.2015.0026.

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Abstract Portosystemic shunts are enlarged vessels that form collateral pathological pathways between the splanchnic circulation and the systemic circulation. Although their causes are multifactorial, portosystemic shunts all have one mechanism in common-increased portal venous pressure, which diverts the blood flow from the gastrointestinal tract to the systemic circulation. Congenital and acquired collateral pathways have both been described in the literature. The aim of this pictorial essay was to discuss the distinct anatomic and imaging features of portosystemic shunts, as well as to provide a robust method of differentiating between acquired portosystemic shunts and similar pathologies, through the use of illustrations and schematic drawings. Imaging of portosystemic shunts provides subclinical markers of increased portal venous pressure. Therefore, radiologists play a crucial role in the identification of portosystemic shunts. Early detection of portosystemic shunts can allow ample time to perform endovascular shunt operations, which can relieve portal hypertension and prevent acute or chronic complications in at-risk patient populations.
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Mahros, AyaM, ReemM Mohammed, YoussefM Sewifee, NahedA Makhlof, HamdyM Ibrahim, and Ahmed Helmy. "Portosystemic collaterals." Journal of Current Medical Research and Practice 6, no. 2 (2021): 109. http://dx.doi.org/10.4103/jcmrp.jcmrp_90_18.

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Vulgamott, Jim C. "Portosystemic Shunts." Veterinary Clinics of North America: Small Animal Practice 15, no. 1 (January 1985): 229–42. http://dx.doi.org/10.1016/s0195-5616(85)50013-3.

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Rao, Prasanna K. S., Keyur A. Sheth, Raghunandan Nadig, Mallikarjun Patil, and Adarsh K. Channagiri. "Portosystemic Myelopathy: A Rare Neurological Presentation of Portosystemic Shunts." Journal of Clinical and Experimental Hepatology 2, no. 4 (December 2012): 393–95. http://dx.doi.org/10.1016/j.jceh.2012.10.005.

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Maddison, J. E., D. Yau, P. Stewart, and G. C. Farrell. "Cerebrospinal fluid γ-aminobutyric acid levels in dogs with chronic portosystemic encephalopathy." Clinical Science 71, no. 6 (December 1, 1986): 749–53. http://dx.doi.org/10.1042/cs0710749.

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1. Cerebrospinal fluid (CSF) γ-aminobutyric acid (GABA) levels were measured in a dog model of spontaneous chronic portosystemic encephalopathy. 2. Dogs with congenital portacaval shunts (intra- or extra-hepatic) develop neurological features of abnormal psychomotor behaviour and depressed consciousness that are consistent with the symptoms of chronic portosystemic encephalopathy in humans. In the five dogs studied, plasma ammonia was elevated, as was CSF tryptophan, both usual biochemical abnormalities in portosystemic encephalopathy. 3. CSF levels of GABA in five dogs with portosystemic encephalopathy (100 ± 13 pmol/ml) were not significantly different from those in five control dogs (96 ± 14 pmol/ml). CSF levels of GABA were not altered after ammonia infusion. 4. If enhanced GABA-ergic neurotransmission, due to influx of gut-derived GABA into the brain, is responsible for the pathophysiology of chronic portosystemic encephalopathy in this model, it is not reflected by increased levels of GABA in CSF.
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Izzo, Francesca, Edoardo Poggi, Francisco J. Pérez Duarte, and Filippo Cinti. "Laparoscopic portosystemic shunt attenuation in two cats." Journal of Feline Medicine and Surgery Open Reports 8, no. 1 (January 2022): 205511692210814. http://dx.doi.org/10.1177/20551169221081416.

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Case series summary Gradual attenuation of an extrahepatic portosystemic shunt using cellophane banding was achieved with a laparoscopic technique in two cats. The portosystemic shunts were treated via a right or left lateral laparoscopic approach. Ultrasonography or CT angiography were used to verify the results of surgery. The success of the procedure was confirmed by normalisation of serum bile acid concentrations and clinical signs at the final re-evaluation. Relevance and novel information The aim of this case series was to determine the feasibility and outcome of laparoscopy for portosystemic shunt attenuation in two cats. Laparoscopic portosystemic shunt attenuation appeared to be a feasible, safe and effective procedure in cats.
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Hüsing-Kabar, A., T. Meister, M. Köhler, W. Domschke, I. Kabar, C. Wilms, B. Hild, HH Schmidt, and HS Heinzow. "Is de novo hepatocellular carcinoma after transjugular intrahepatic portosystemic shunt increased?" United European Gastroenterology Journal 6, no. 3 (September 20, 2017): 413–21. http://dx.doi.org/10.1177/2050640617732886.

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Background Portal hypertension is a major complication of liver cirrhosis. Transjugular intrahepatic portosystemic shunt is effective in treatment of portal hypertension. However, decreased parenchymal portal venous flow after transjugular intrahepatic portosystemic shunt insertion favours ischaemic liver injury which has been discussed to induce hepatocarcinogenesis causing hepatocellular cancer. Aim This study aimed to explore the association between transjugular intrahepatic portosystemic shunt placement and the development of hepatocellular cancer. Methods A total of 1338 consecutive liver cirrhosis patients were included in this retrospective study between January 2004–December 2015. Data were analysed with regard to development of hepatocellular cancer during follow-up. Binary logistic regression and Kaplan-Meier analyses were conducted for the assessment of risk factors for hepatocellular cancer development. In a second step, to rule out confounders of group heterogeneity, case-control matching was performed based on gender, age, model of end-stage liver disease score and underlying cause of cirrhosis (non-alcoholic steatohepatitis, alcoholic liver disease and viral hepatitis). Results Besides established risk factors such as older age, male gender and underlying viral hepatitis, statistical analysis revealed the absence of transjugular intrahepatic portosystemic shunt insertion as a risk factor for hepatocellular cancer development. Furthermore, matched-pair analysis of 432 patients showed a significant difference ( p = 0.003) in the emergence of hepatocellular cancer regarding transjugular intrahepatic portosystemic shunt placement versus the non-transjugular intrahepatic portosystemic shunt cohort. Conclusion In patients with end-stage liver disease, transjugular intrahepatic portosystemic shunt insertion is significantly associated with reduced rates of hepatocellular cancer development.
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Durleshter, V. M., S. A. Gabriel’, N. V. Korochanskaya, A. Yu Buhtoyarov, P. V. Markov, D. S. Murashko, O. A. Oganesyan, L. G. Izmailova, M. A. Basenko, and Yu V. Horon'ko. "Transjugular intrahepatic portosystemic stent-shunt as minimally invasive method of portal hypertension correction in multi-disciplinary clinic." Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery 25, no. 4 (December 17, 2020): 95–106. http://dx.doi.org/10.16931/1995-5464.2020495-106.

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Aim. Optimization of the tactics of management of patients with liver cirrhosis who underwent Transjugular Intrahepatic Portosystemic Shunt – TIPS based on own experience and literature data. Materials and methods. From 2014 to 2019 years 51 Transjugular Intrahepatic Portosystemic Shunt procedures were performed. Results. The indications for Transjugular Intrahepatic Portosystemic Shunt procedure were detailed. The tactics of treatment in post-operative period was assessed. Shot-term and long-term results of the treatment were discussed. Especial attention was put to persons who included in patient list of liver transplantation. Conclusion. Transjugular Intrahepatic Portosystemic Shunt allows obtaining stable decompression in portal system that reduces frequency of bleeding relapse from gastric and esophageal veins. The mortality was decreased, and patients can wait till liver transplantation.
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Dissertations / Theses on the topic "Portosystemic"

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Jalan, Rajiv. "Transjugular intrahepatic portosystemic stent-shunt." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/22346.

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The purpose of this thesis was to evaluate (i) the effect of TIPSS on the natural history of cirrhosis (ii) the changes in shunt function following its insertion and study the potential pathogenic mechanisms (iii) the place of TIPSS in the management of variceal haemorrhage in patients with cirrhosis and (iv) the use of TIPSS as a 'model' to study the pathogenesis of sodium retention in patients with cirrhosis. The thesis aims to answer these questions by studying defined cohorts of patients with cirrhosis and portal hypertension undergoing TIPSS insertion for a variety of indications. The thesis is divided into various sections which deal with the above questions. The first section deals with the outcome of patients with cirrhosis treated with TIPSS and assesses the factors predicting mortality, rebleeding, encephalopathy and shunt insufficiency. It also prospectively assesses changes in liver function, neuropsychological profile, haematological profile and appraises their relationship with changes in the portal pressure. Studies in the next section were designed to evaluate the methods for assessment of shunt function and to study the pathogenesis of shunt insufficiency. The place of TIPSS in the management of variceal haemorrhage in patients with cirrhosis is evaluated in a randomised and controlled study in comparison with variceal band ligation. The last section looks at the mechanisms of sodium retention in cirrhosis particularly with reference to the 'hepatorenal reflex'. The final chapter is dedicated to discussing the findings of this study in the light of the available literature and define the areas of deficiency in our understanding and to outline future perspectives. In conclusion, TIPSS is an exciting innovation which is relatively safe and can be performed in the vast majority of patients with cirrhosis with a very low procedure related mortality. Although its place in the management of uncontrolled variceal haemorrhage appears certain, further controlled studies are needed to assess its role in the secondary prophylaxis of variceal haemorrhage and in refractory ascites.
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Rosenqvist, Kerstin. "Transjugular intrahepatic portosystemic shunt in the treatment of symptomatic portal hypertension." Doctoral thesis, Uppsala universitet, Radiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-321538.

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Portal hypertension (PHT) is a condition with serious complications, such as variceal bleeding, refractory ascites and bowel ischemia. The cause of PHT may be pre-, intra- or post-hepatic. Initial treatment is pressure-reducing drugs and the treatment of acute symptoms. Ten patients presented with severe abdominal pain and acute portomesenteric venous thrombosis. Their response to systemic anticoagulation was insufficient. Treatment with primary continuous thrombolysis by a transhepatic or transjugular approach in four patients resulted in major complications, incomplete recanalization and a 75% survival rate. Treatment with repeated transjugular thrombectomy (TT) combined with the creation of a transjugular intrahepatic portosystemic shunt (TIPS) achieved near complete recanalization, prompt symptom relief and 100% survival in five patients treated with this method as the primary intervention. In one patient, treated with TT and TIPS secondary to surgical thrombectomy and bowel resection, the outcome was fatal. Nineteen patients with portal vein thrombosis presented with acute or threatening variceal bleeding or refractory ascites. TIPS was feasible in 16 of the 18 patients in whom it was attempted and symptom relief was achieved in the majority of them. In 14 patients with Budd-Chiari syndrome, 13 patients were treated with TIPS, four of them after previous liver vein angioplasty. The 5-year transplantation-free survival rate was 100% in patients treated with primary TIPS. In 131 patients with variceal bleeding treated with TIPS, the survival at 12 months in patients with and without cirrhosis was 70% and 100% respectively and in accordance with previous studies. A high Child-Pugh score prior to TIPS and severe HE within 12 months after TIPS was related to an increased mortality. The occurrence of HE after TIPS did not correlate with the PSG after TIPS. Re-bleeding within 12 months after TIPS occurred in 10 patients and was associated with TIPS dysfunction. In conclusion, endovascular intervention, mainly TIPS, seems to be safe and effective for treating patients with complications of PHT, regardless of the underlying cause of disease and site of venous blood flow obstruction. HE may occur more frequently after TIPS than medical and endoscopic treatment, but is often mild and easily treated. In selected patients with PHT, TIPS may improve survival.
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Barrera, Gutierrez Juan Carlos. "Transjugular Intrahepatic Portosystemic Shunt (Tips), Duration of Procedural Time and Correlation with Early Morbidity and Mortality." Kent State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=kent1628778237908844.

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Tivers, Michael Samuel. "The role of hepatic regeneration and angiogenesis in the response to surgical attenuation of congenital portosystemic shunts in dogs." Thesis, Royal Veterinary College (University of London), 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618310.

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Ernandes, Mariane Ceschin. "Avaliação do metabolismo proteico e aminoacídico de cães com shunt portossistêmico." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-04122018-115325/.

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No desvio portossistêmico, o sangue proveniente do trato gastrintestinal não é direcionado ao fígado para ser metabolizado e sim desviado para a circulação sistêmica. O acúmulo dessas substâncias tóxicas associado às alterações funcionais do órgão pode resultar em encefalopatia hepática. O manejo nutricional é o ponto chave para o sucesso da terapia. Dessa forma, o presente estudo objetivou avaliar os efeitos do emprego de um alimento hipoproteico nas concentrações séricas aminoacídicas de cães com desvio portossistêmico. Foram incluídos nove cães com diagnóstico de desvio portossistêmico (Shunt) e nove cães saudáveis (Controle). Os animais foram avaliados no dia um (T0) e após 60 dias (T60) de ingestão de uma dieta hipoproteica comercial. Nos dois momentos foram coletadas amostras de sangue para realização de hemograma, leucograma, bioquímica sérica, determinação dos aminoácidos séricos e amônia. A análise estatística dos resultados referentes aos hemogramas e exames bioquímicos foi baseada em um modelo misto que considerou efeito fixos de grupo, tempo e interação e, para os aminoácidos somente efeitos fixos de grupo (p<0,05). Os animais do grupo controle apresentaram maiores valores de proteína total (p<0,0001), ureia (p<0,0001), creatinina (p=0,0163), albumina (p<0,0001) e colesterol (p=0,0012) quando comparado ao grupo Shunt que apresentou maiores valores de hematócrito (p=0,0213), ALT e FA (p=0,0253 e p=0,0004, respectivamente), amônia em jejum (p=0,0083) e amônia pós-prandial (p=0,0036). Em relação aos aminoácidos séricos, o grupo Shunt apresentou valores maiores quando comparados ao grupo Controle nas concentrações dos aminoácidos fenilalanina (p=0,0054), glutamato (p=0,0066), serina (p=0,0054) e tirosina (p=0,0106), já o aminoácido sérico alanina (p=0,0280), a razão de Fischer (p=0,0093) e a razão da concentração sérica de aminoácidos de cadeia ramificada e tirosina (p=0,0243) foram maiores no grupo Controle. Concluiu-se que o manejo dietético foi eficiente em prevenir a progressão da doença e controlar os sinais clínicos, sem promover aumento nas concentrações séricas dos aminoácidos de cadeia ramificada.
In the portosystemic shunt, the blood coming from the gastrointestinal tract is not directed to the liver to be metabolized but rather diverted to the systemic circulation. The accumulation of these toxic substances associated with functional alterations of the organ can result in hepatic encephalopathy. Nutritional management is the key to successful therapy. Thus, the present study aimed to evaluate the effects of the use of a hypoproteic food on the protein and amino acid profile of dogs with portosystemic shunt. For this, nine dogs with a diagnosis of portosystemic shunt (Shunt) and nine healthy dogs (Control) were included. The dogs were evaluated on day one (T0) and after 60 days (T60) feeding a commercial hypoprotein diet. Blood samples were collected for hemogram, leukogram, serum biochemistry, determination of serum amino acids and ammonia. For the analysis of hemograms and biochemistry, a mixed model was used considering group fixed effects, time and interaction, and for amino acids only group fixed effects (p<0.05). The results showed that the animals in the Control group presented higher values of total protein (p<0.0001), urea (p<0.0001), creatinine (p=0.0163), albumin (p<0.0001) and cholesterol (p=0.0012) when compared to the Shunt group that presented higher values of hematocrit (p=0.0213), ALT and FA (p=0.0253 and p=0.0004, respectively), fasting ammonia (p=0.0083) and postprandial ammonia (p=0.0036). Serum amino acids (p=0.0054), glutamate (p=0.0066), serine (p=0.0054) and tyrosine (p=0.0054) were higher in the Shunt group than in the Control group (0.0106). The Fischer ratio (p=0.0093) and the ratio of serum concentration of branched-chain amino acids and tyrosine (p=0.0243) were higher for the Control group. In conclusion, that dietary management was efficient in preventing disease progression and controlling clinical signs without increasing branched-chain amino acids.
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Kamikawa, Lilian. "Avaliação morfométrica e hemodinâmica comparativa dos vasos envolvidos no desvio portossistêmico em cães." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-10042008-150101/.

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Foi realizado o estudo morfométrico e o estudo hemodinâmico da veia porta em vinte cães normais, de idade igual e inferior a 120 dias, e em cinco cães portadores de desvio portossistêmico, de idades entre 90 e 360 dias. Dois animais do grupo de cães portadores de desvio portossistêmico foram submetidos ao tratamento cirúrgico (colocação de anel ameróide) e avaliações subseqüentes ao procedimento cirúrgico foram realizados. Nos cães do grupo normal, as margens hepáticas apresentaram-se entre 1,50cm e 3,00cm depois da margem costal. As médias dos diâmetros médios da veia porta (VP), veia cava caudal (VCC) e aorta abdominal (AO) obtidas foram respectivamente, 0,38cm, 0,37cm e 0,41cm. As proporções entre os diâmetros médios VP/VCC e VP/AO apresentaram médias de 1,10 e 0,94, respectivamente. As médias das áreas de VP, VCC e AO mediram respectivamente, 0,12cm2, 0,11cm2 e 0,14cm2. No estudo hemodinâmico de VP destes animais, utilizando-se o ultra-som Doppler, a velocidade média de fluxo sangüíneo portal (VMFSP) mediu 17,77cm/s. A média de fluxo sangüíneo portal (FSP) mediu 83,11ml/min/kg. O índice de congestão (IC) apresentou média de 0,009. Para o grupo de cães portadores de desvio portossistêmico, o fígado apresentou redução de seu volume, sendo visibilizado entre 1,00cm e 2,00cm antes da margem costal. No estudo morfométrico, as médias dos diâmetros médios obtidos de VP, VCC e AO mensuraram respectivamente, 0,52cm, 0,79cm e 0,58cm. As proporções entre os diâmetros médios VP/VCC e VP/AO mediram respectivamente, 0,62 e 0,84. As médias das áreas de VP, VCC e AO mediram respectivamente, 0,22cm2, 0,56cm2 e 0,27cm2. Ao ultra-som Doppler a VMFSP mediu 26,10cm/s e a média do IC obtido foi de 0,009. Nos animais do grupo de cães portadores de desvio portossistêmico submetidos ao procedimento cirúrgico, foi observado aumento de volume hepático na semana seguinte à colocação do anel ameróide e a VMFSP manteve-se inferior a 19,50cm/s em todos exames subseqüentes à cirurgia no cão 1.
The morphometry and haemodynamic aspects of portal vein were studied in 20 normal dogs with less than 120 days of age and in 5 dogs presenting portosystemic shunting with ages between 90 and 360 days. 2 dogs of the group of animals with portosystemic shunting were submitted to surgical treatment, using a specialized device (ameroid constrictor). Subsequent evaluations were made after the surgical procedure. In the normal group the hepatic margins were seen 1.50cm to 3.00cm below de costal margin. Collected data indicated that the mean diameter of portal vein (VP), caudal vena cava (VCC) and abdominal aorta (AO) measured respectively, 0.38cm, 0.37cm and 0.41cm. The VP/VCC and VP/AO mean ratios were respectively, 1.10 and 0.94. The average of VP, VCC and AO areas were respectively, 0.12cm2, 0.11cm2 and 0.14cm2. The haemodynamic of portal vein was studied by ultrasound Doppler and the mean velocity of portal blood flow (VMFSP) measured was 17.77cm/s. It was verified that portal blood flow (FSP) average was 83.11ml/min/kg and the congestion index (IC) average was 0.009. In the group of animals presenting portosystemic shunting, the hepatic margins were seen 1.00cm to 2.00cm above the costal margin. The morphometry of VP, VCC and AO presented a mean diameter of 0.52cm, 0.79cm and 0.59cm, respectively. The VP/VCC and VP/AO mean ratios were respectively, 0.62 and 0.84. The average of VP, VCC and AO areas were respectively, 0.22cm2, 0.56cm2 and 0.27cm2. The haemodynamic study demonstrated that the VMFSP measured was 26.10cm/s and de IC average was 0.009. In the group of animals with portosystemic shunting which were submitted to surgical treatment, an increase of the liver size was seen from the first ultrasonographic evaluation. The measurements of VMFSP collected in the post surgical period were <= 19.50cm/s in dog 1.
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Pina, Mónica Patrícia Pereira. "Tratamento cirúrgico de shunts portossistémicos congénitos em cães : estudo retrospetivo de 13 casos clínicos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2020. http://hdl.handle.net/10400.5/20544.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Os shunts portossistémicos congénitos (SPS) correspondem a malformações vasculares que estabelecem uma comunicação entre a circulação venosa portal e a circulação sistémica, e afetam mais frequentemente os cães de raça pura. Apesar de o tratamento médico ser a primeira abordagem em cães com SPS congénito, a completa resolução clínica está dependente da correção cirúrgica. Este estudo pretendeu caracterizar uma amostra de 13 cães com diagnóstico de SPS que foram submetidos a correção cirúrgica, procurando correlacionar os parâmetros clínicos e laboratoriais com a ocorrência de complicações pós-cirúrgicas a curto e a longo prazo. A amostra em estudo incluiu 8 fêmeas e 5 machos, com idades compreendidas entre os 2 meses e os 4 anos, pertencentes às raças Yorkshire terrier (n=5), Caniche anão (n=2), Chihuahua (n=1), Retriever do Labrador (n=1), Schnauzer miniatura (n=1) e Shih Tzu (n=1), incluindo também cães sem raça definida (n=2). Todos os indivíduos foram submetidos a correção cirúrgica de shunt portossistémico através de técnicas extravasculares de oclusão parcial, que tiveram lugar no Centro Hospitalar Veterinário e no Hospital Referência Veterinária Montenegro. A grande maioria dos cães apresentava SPS de localização extra-hepática (n=12) e apenas um cão apresentava um SPS intra-hepático. As complicações pós-cirúrgicas afetaram mais de metade da amostra (n=7) e incluíram hipertensão portal (n=3), alterações neurológicas (n=1), hipoglicemia (n=1), recorrência de sinais clínicos (n=2) e morte (n=1). Apesar de não existir uma correlação estatisticamente significativa entre o BUN e a ocorrência de complicações pós-cirúrgicas, verificou-se haver uma tendência para os cães com valores inferiores de BUN apresentarem uma maior incidência de complicações pós-cirúrgicas a curto prazo. Concluímos que a manifestação clínica desta doença tende a ser precoce (cães com idade inferior a 1 ano), sendo os sinais gastrointestinais os mais frequentemente descritos e a raça Yorkshire terrier a mais frequentemente afetada. O tamanho reduzido da amostra, a existência de historiais médicos incompletos e a discrepância entre protocolos médicos foram as principais limitações deste estudo, impedindo a obtenção de resultados estatisticamente significativos. Mais estudos serão necessários para padronizar as inúmeras variações morfológicas dos shunts e para determinar quais os fatores associados a um melhor prognóstico.
ABSTRACT - SURGICAL TREATMENT OF CONGENITAL PORTOSYSTEMIC SHUNTS IN DOGS: RETROSPECTIVE STUDY OF 13 CLINICAL CASESCongenital portosystemic shunts are vascular malformations that provides communication between portal and systemic circulation, which typically affects purebred dogs. Although medical treatment is the first-line option for dogs with congenital portosystemic shunt, the complete clinical recovery depends of surgical intervention. This study intended to characterize a sample of 13 dogs with portosystemic shunt diagnosis which were submitted to surgical correction and to correlate the clinical and laboratory parameters with the occurrence of short-term and long-term postoperative complications. The studied sample included 8 females and 5 males, with an age interval between 2 months and 4 years, belonging to the breeds Yorkshire terrier (n=5), Toy Poodle (n=2) , Chihuahua (n=1), Labrador Retriever (n=1), Miniature Schnauzer (n=1) and Shih Tzu (n=1), including mixed-breed dogs (n=2). All dogs were treated using extravascular surgical techniques for gradual occlusion portosystemic shunts, which took place at the Centro Hospitalar Veterinário and Hospital Referência Veterinária Montenegro. The majority of the dogs had an extrahepatic shunt (n=12) and only one dog presented an intrahepatic shunt. Postoperative complications affected more than half of the sample (n=7) and included portal hypertension (n=3), post attenuation neurological signs (n=1), hypoglycemia (n=1), recurrence of clinical signs (n=12) and death (n=1). Although there isn’t a significant correlation between BUN and postoperative complications, it was observed a tendency for dogs with lower BUN to have a higher incidence of short-term postoperative complications. We conclude that the clinical manifestation of this disease tends to be early (dogs under 1- year age), the gastrointestinal symptoms were the most reported and the Yorkshire terrier were the breed most affected. A small sample size, incomplete medical records and discrepancy between the medical protocols were the major limitations in this study, that could explain the upsense of statistically significant results. More studies will be required to describe the numerous variations in the morphology of the shunts and to identify the factors associated with a better prognosis.
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Schmidt, Peter. "Prä- und postoperative Untersuchungen bei Hunden mit angeborenem Portosystemischen Shunt unter besonderer Berücksichtigung der Serumgallensäurenkonzentration nach Stimulation mit Ceruletid." Doctoral thesis, Universitätsbibliothek Leipzig, 2004. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-36974.

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Es wurden 44 Hunde mit einem kongenitalen Portosystemischen Shunt präoperativ hinsichtlich ihrer Leberzellintegrität (ALT, AP, GLDH, GGT) und ihrer hepatischen Synthese- (Harnstoff, Cholesterin, Albumin) bzw. Metabolisierungsrate (Ammoniak) untersucht. Die hepatische Durchblutungs- und Resorptionsrate wurde anhand des Verlaufs der Serumgallensäuren im Gallensäuren-Stimulationstest mit Ceruletid (0,3µg/kg KM i.v.)vor und 30 min nach Stimulation (FSBA; PSBA) beurteilt. Eine Verlaufsuntersuchung erfolgte bei den Hunden, bei denen das Shuntgefäß in zwei Operationen verschlossen worden war. Die Untersuchungen wurden jeweils prae operationem, am zweiten, vierten und siebten Tag post operationem sowie abschließend mindestens 120 Tage nach vollständigem Verschluss des Shuntgefäßes durchgeführt. Es wurden die Ergebnisse der einzelnen Untersuchungstage untereinander mit Hilfe des gepaarten t-Tests sowie mit einer Kontrollgruppe (63 lebergesunde Hunde)unter Anwendung des unpaaren t-Tests verglichen
The hepatic enzymes: alanine aminotransferase (ALT), alkaline phosphatase (AP), glutamat dehydrogenase (GLDH), gamma-glutamyl transferase (GGT); the hepatic synthetic (urea, cholesterol, albumin) and metabolic activity (ammonia) and the hepatic blood flow (serum bile acid stimulation test) were determined in 44 dogs with congeintal portosystemic shunt and in 63 healthy dogs. After determination of fasting serum bile acids (FSBA), the gallbladder contraction was induced by administration of 0,3µg/kg iv ceruletide (Takus). Blood samples of the poststimulatin serum bile acids (PSBA) were taken 30 minutes post administration. The portosystemic shunt was first attenuated (surgery 1) and 4 weeks later completely ligated (surgery 2). All dogs treated with this surgical procedure were examined with the described laboratory design before surgery, the second, the fourth, the seventh day after surgery and approxiamtely 120 days after complete ligation in a follow up study. To compare the developmentof the biochemical and hepatic alterations the paired and unpaired t-test were used
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Lopes, Paula Alexandra Ferreirinha. "Caracterização clínica e laboratorial dos diferentes tipos morfológicos de shunts portossistémicos congénitos extra-hepáticos na espécie canis familiaris : estudo retrospetivo." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/18273.

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Dissertação de Mestrado Integrado em Medicina Veterinária
O shunt portossistémico (SPS) de origem congénita pode ser intra ou extra-hepático, e é uma comunicação macrovascular entre a veia porta ou suas tributárias e a veia cava caudal ou outra veia sistémica (ázigos e frénica) sem atravessar o parênquima hepático, resultando em consequências sistémicas expressas pela sintomatologia clínica do doente, a qual se relaciona com o grau de compromisso hepático e com a localização desse desvio. O presente estudo retrospetivo foi realizado com uma amostra de 26 cães (N=26), diagnosticados com SPS congénito extra-hepático, dividida em dois grupos de acordo com o local de inserção: 1) caudal ao fígado (esplenocava e gastrocava direita) e 2) diafragmática (gastrocava esquerda, gastrofrénica esquerda e gastroázigos esquerda). O objetivo do estudo foi tentar estabelecer uma relação entre os parâmetros clínicos e analíticos laboratoriais do doente com SPS e os principais locais de inserção. De acordo com os resultados obtidos, verificou-se que, a idade do aparecimento dos sinais clínicos parece estar relacionada com o local de inserção (p=0,006), sendo os doentes com shunt com inserção na veia frénica e ázigos diagnosticados com idades ≥ a 2 anos. De igual modo, a encefalopatia hepática esteve presente de forma estatisticamente significativa em quase todos os pacientes com shunt com inserção caudal ao fígado (p=0,05). À exceção do shunt gastroázigos esquerda, verificou-se a presença de atraso no crescimento e baixa condição corporal para todos os doentes com SPS. Da relação com a analítica laboratorial apenas se verificou diferenças significativas para o parâmetro hematócrito (p=0,01), o qual estava mais baixo nos shunts com inserção caudal ao fígado. No que respeita à urinálise, verificou-se que com idade >12 meses, têm maior predisposição para cristalúria e calculose (p=0,02). Por se tratar de um estudo retrospetivo, a falta de uniformidade no que respeita aos dados referentes de cada doente surge como uma limitação que poderá ter contribuído para os resultados obtidos.
ABSTRACT - CLINICAL AND LABORATORIAL CHARACTERIZATION OF THE DIFFERENT MORPHOLOGIC TYPES OF CONGENITAL EXTRAHEPATIC PORTOSYSTEMIC SHUNTS IN THE SPECIES CANIS FAMILIARIS – RETROSPETIVE STUDY - Congenital portosystemic shunt (CPSS) are macrovascular communication between the portal vein or its tributaries and the caudal vena cava or other systemic veins (azygos and phrenic), and they can be intra or extrahepatic. Different systemic consequences with a various clinical signs and symptoms are seen in these patients, being related to the level of hepatic impairment and its location. This retrospective study used a sample of 26 dogs (N=26), diagnosed with extrahepatic CPSS. The sample was divided in two groups according to the region of the shunt insertion: 1) caudal to the liver (spleno-caval and right gastro-caval) and 2) diaphragmatic (left gastro-caval, left gastro-phrenic and left gastro-azygos). The aim of the study was to understand the presence or not, of relationship between the clinical and laboratorial parameters and the region of the CPSS insertion. According to the results, the age of the onset of clinical signs seems to be related to the region of the CPSS insertion (p=0,006), with a insertion in the phrenic and azygos vein being diagnosed in patients with more than 2 years old. Hepatic encephalopathy was presented in almost patients with shunt with insertion caudal to liver (p=0,05), and except for the left gasto-azygos shunt, the presence of stunted growth and poor weight gain was found in all patients with CPSS. Regarding to the laboratory parameters studied, statistical significant differences were registered only for the hematocrit which was lower in CPSS with insertion caudal to the liver (p=0,01). Also, it was possible to notice that patients older than 12 months are more prone to develop crystalluria and calculosis (p=0,02). The lack of uniformity in each patient data was the major limitation presented by the study, and it have contributed to the results obtained.
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Poincloux, Laurent. "Shunt portosystémique par échoendoscopie sur modèle animal." Thesis, Clermont-Ferrand 1, 2016. http://www.theses.fr/2016CLF1MM08.

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L’échoendoscopie thérapeutique occupe une place croissante et incontournable de l’activité médico-chirurgicale en pathologie digestive depuis le développement des sondes sectorielles. Les domaines d’application de cette technique interventionnelle mini-invasive sont de plus en plus nombreux, d’une part en pathologie biliopancréatique et entérale permettant la réalisation d’anastomoses évitant un recours à la chirurgie traditionnelle, et d’autre part en cancérologie digestive car elle permet de délivrer un agent thérapeutique, une source de rayonnement ou des cellules liées au système immunitaire dans une lésion ciblée. L’abord vasculaire est une voie récente et prometteuse de l’échoendoscopie interventionnelle offrant des perspectives thérapeutiques en hépatologie notamment dans le domaine de l’hypertension portale. Ce travail se décompose en trois parties décrivant successivement l’état de l'art des applications de l’échoendoscopie interventionnelle, puis deux travaux originaux expérimentaux : dans un premier temps, le transfert de la technique d’anastomose biliodigestive (réalisée régulièrement dans notre centre) à l’abord vasculaire portosystémique sur animal sain, puis dans un deuxième temps la validité de la technique sur modèle animal de fibrose hépatique. La première série d’expérimentations a permis de mettre au point la technique de création d’un shunt intrahépatique portosystémique par échoendoscopie chez 23 cochons sains, en collaboration avec l’équipe de radiologie vasculaire. Ces procédures ont été réalisées dans une salle de cathétérisme vasculaire expérimentale (laboratoire Caviti) dans le cadre du laboratoire d’accueil ISIT (Image Science for Interventional Techniques, Pr. L. Boyer, Pr. J.-Y. Boire, UMR CNRS/UDA 6284). Les résultats ont été concluants puisque le shunt est apparu faisable dans 91% des cas, fonctionnel dans 81% des cas avec une morbidité de 14,2%. La deuxième série d’expérimentations a permis de valider cette technique d’échoendoscopie chez un modèle porcin de fibrose hépatique par embolisation radiologique, en collaboration avec l’Institut National de Recherche Agroalimentaire de Theix pour la stabulation des animaux. Ce travail multidisciplinaire a permis une collaboration étroite entre endoscopistes, radiologues, chirurgiens viscéraux et anatomopathologistes, s’inscrivant dans une démarche de recherche transversale. Les résultats sont encourageants puisqu’un shunt intrahépatique porto-systémique par échoendoscopie s’est révélé techniquement faisable et fonctionnel sur modèle de fibrose hépatique avec une survie à 7 jours des animaux dans deux tiers des cas. Avant d’envisager une étude princeps chez l’homme, des études complémentaires sont néanmoins nécessaires sur des modèles porcins présentant une fibrose hépatique associée à une hypertension portale en augmentant la durée de stabulation, en homogénéisant la procédure de squelettisation de l’artère hépatique et en adaptant la dose de solution injectée. Cette technique pourrait constituer à terme une alternative en cas d’échec de la technique standard pour complications de l’hypertension portale (shunt intrahépatique portosystémique par voie transjugulaire) chez des patients alors en situation d’impasse thérapeutique
Therapeutic endoscopic ultrasonography is a growing and essential part of the medical and surgical activity in digestive pathology since the development of sectoral probes. The fields of application of this minimally invasive interventional technique are more and more numerous, on the one hand in biliopancreatic and enteral pathology, allowing the realization of anastomoses without traditional surgery, and on the other hand in digestive oncology, because it makes it possible to deliver a therapeutic agent, a source of radiation or cells linked to the immune system in a targeted lesion. The vascular approach is a recent and promising way of interventional endoscopic ultrasound offering therapeutic perspectives in hepatology, especially in the field of portal hypertension.This work is divided into three parts successively describing the state of the art of the applications of interventional ultrasonoscopy, then two original experimental works: initially, the transfer of the technique of biliodigestive anastomosis (performed regularly in our center ) at the portosystemic vascular approach on healthy animal, then in a second time the validity of the animal model technique of liver fibrosis.The first series of experiments led to the development of the technique for the creation of an intrahepatic shunt portosystemic by echoendoscopy in 23 healthy pigs, in collaboration with the vascular radiology team. These procedures were performed in an experimental vascular catheterization room (Caviti laboratory) as part of the ISIT host laboratory (Image Science for Interventional Techniques, Prof. L. Boyer, Pr. J.-Y.Boire, UMR CNRS / UDA 6284). The results were conclusive since the shunt appeared feasible in 91% of cases, functional in 81% of cases with a morbidity of 14.2%. The second series of experiments validated this endoscopic ultrasound technique in a porcine model of liver fibrosis by X-ray embolization, in collaboration with Theix National Institute for Food Research for Animal Stabling. This multidisciplinary work has allowed close collaboration between endoscopists, radiologists, visceral surgeons and anatomopathologists, as part of a transversal research approach. The results are encouraging since a porto-systemic intrahepatic shunt by endoscopic ultrasonography proved to be technically feasible and functional on a hepatic fibrosis model with a 7-day survival of the animals in two-thirds of the cases. Before considering a primary study in humans, additional studies are nevertheless necessary on porcine models presenting hepatic fibrosis associated with portal hypertension by increasing the duration of stabulation, by homogenizing the procedure of skeletonization of the hepatic artery and by adjusting the dose of injected solution. This technique could eventually be an alternative in case of failure of the standard technique for complications of portal hypertension (intrahepatic portosystemic shunt transjugular) in patients then in a situation of therapeutic impasse
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Books on the topic "Portosystemic"

1

1925-, Conn Harold O., ed. TIPS: Transjugular intrahepatic portosystemic shunts. New York: Igaku-Shoin, 1996.

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(Editor), Harold O. Conn, Julio Palmaz (Editor), Josef Rosch (Editor), and Martin Rossle (Editor), eds. Tips: Transjugular Intrahepatic Portosystemic Shunts. Igaku-Shoin Medical Pub, 1996.

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TIPS: Transjugular intrahepatic portosystemic shunts. Igaku-Shoin, 1996.

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Grosso, Maurizio, Gerd Noldge, and Cesare Fava. Transjugular Intrahepatic Portosystemic Shunt (TIPS) indications, techniques and results. Idelson-Gnocchi Ltd. Publishing, 1998.

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Kinney, Thomas, and Kazim Narsinh. Use of Prolapsing Guidewire to Secure Portal Venous Access During the TIPS Procedure. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0075.

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Perhaps the most critical portion of the transjugular intrahepatic portosystemic shunt procedure involves obtaining secure portal venous access. An acute angle of entry into the portal venous system during intrahepatic portosystemic shunt creation can make retrograde advancement of a guidewire into the splenic or superior mesenteric vein difficult. However, securing access from the jugular access site to the portal system with a reliable guidewire is of critical importance during the procedure. This chapter presents a technique to advance a flexible-tip guidewire antegrade into right portal vein branches prior to prolapsing the guidewire into the main portal vein to secure transjugular portal venous access.
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Irani, Zubin, and Sara Zhao. Adjustable Small-Diameter TIPS. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0081.

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Transjugular intrahepatic portosystemic shunt (TIPS) was first described by Rosch et al. in 1969, and in 1982, Colopinto et al. described its first clinical application in a patient with cirrhosis and variceal hemorrhage. It was not until 1988 that the first metal-lined shunt was created, and in 1997 the first polytetrafluoroethylene (PTFE)-lined stent was used in humans for shunt revision after stenosis, created by pinning the Gore PTFE graft material between two metal stents. Introduced in 2000, the Viatorr stent graft is now the most commonly used device for TIPS. One of the major side effects of TIPS creation is hepatic encephalopathy (HE). This chapter discusses the adjustable small-diameter transjugular intrahepatic portosystemic shunt.
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Ferral, Hector. Optimal Imaging Techniques of the Portal Vasculature During TIPS Creation: Use of the CO2 Portogram. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0074.

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Transjugular intrahepatic portosystemic shunt creation is one of the most complex interventional procedures. It requires skills in imaging, vessel catheterization, guidewire techniques, balloon angioplasty, endovascular stent deployment, and embolization techniques. The key step during this procedure is obtaining access into the portal vein. This chapter discusses how to perform a CO2 portogram to obtain access to the portal vein during the creation of a transjugular intrahepatic portosystemic shunt (TIPS). The CO2 portogram may be performed with an angiographic catheter wedged in the hepatic vein, with an occlusion balloon inflated within the hepatic vein, or with the transhepatic needle within the liver parenchyma—the so-called “intraparenchymal” injection. Those performing a CO2 portogram should have knowledge of CO2 and a user-friendly CO2 delivery system to avoid common CO2 complications.
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Williams, Ashleigh, and John Christie. Hepatic disease. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198719410.003.0007.

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This chapter describes the anaesthetic management of the patient with liver disease and its sequelae. Acute liver failure and chronic liver failure are discussed, together with their anaesthetic implications on coagulation and drug metabolism. Major sequelae of liver disease are discussed, including portal hypertension, varices, and hepatorenal syndrome. The preoperative investigation and optimization, treatment, and anaesthetic management of the patient with liver failure are described. The investigation and management of post-operative liver dysfunction are described. The anaesthetic management of acute oesophageal variceal haemorrhage and transjugular intrahepatic portosystemic shunt (TIPSS) are described.
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Plotnik, Adam N., and Stephen Kee. Advancing the TIPS Sheath Through a Difficult Cirrhotic Liver: Pay It Forward Off the Balloon. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0076.

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The “pay it forward off the balloon” technique for advancing the transjugular intrahepatic portosystemic shunt (TIPS) sheath may be employed during a difficult TIPS case when the interventionalist has already accessed the portal vein but cannot get the standard 10 Fr TIPS sheath through the fibrotic tract into the portal vein to thereby allow placement of a standard TIPS covered stent. In some patients, the fibrotic recoil of the parenchymal hepatic tract can be so severe that the basic balloon dilation maneuver fails. The pay it forward off the balloon technique employs the use of a 6 mm × 4-cm balloon, which is placed through the 10 Fr TIPS sheath and advanced over the wire and across the fibrotic tract into the portal vein.
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Kahn, S. Lowell. The Gun-Site and Percutaneous Portocaval Techniques for the Challenging TIPS. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0077.

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Since its inception, the “Achilles’ heel” of the transjugular intrahepatic portosystemic shunt (TIPS) procedure has been catheterization of the portal vein from the systemic venous circulation. In the majority of TIPS procedures, the portal vein is readily identified with conventional technique and the procedure is completed in no more than 60–90 minutes, if not less. However, there are certain anatomic situations that can make performance of a TIPS procedure difficult. A small cirrhotic liver with an abnormal hepatic to portal venous orientation, t hrombosis or cavernous transformation of the portal vasculature, and atrophic or absent (Budd–Chiari) hepatic veins all produce unique challenges for the interventionalist. In such situations, the use of alternative TIPS techniques may be warranted. In this chapter, two alternative TIPS techniques are discussed to assist with challenging anatomy.
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Book chapters on the topic "Portosystemic"

1

Kirby, Barbara. "Portosystemic." In Complications in Small Animal Surgery, 461–66. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119421344.ch63.

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Shaw, Jawaid, and Jasmohan S. Bajaj. "Portosystemic Encephalopathy." In Liver Disorders, 481–506. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30103-7_29.

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Monnet, Eric, Lisa Klopp, Angela J. Marolf, Eric Monnet, Craig B. Webb, Ronald Bright, and Daniel D. Smeak. "Portosystemic Shunts." In Small Animal Soft Tissue Surgery, 407–40. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118997505.ch43.

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Braun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "Portosystemic Encephalopathy." In Encyclopedia of Molecular Mechanisms of Disease, 1703. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_8713.

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Keller, Ninette. "Portosystemic Liver Shunts." In Chronic Disease Management for Small Animals, 239–41. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119201076.ch24.

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Weisse, Chick. "Portosystemic Shunt Embolization." In Veterinary Image-Guided Interventions, 215–26. Oxford: John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118910924.ch21.

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Garcia-Pagán, Juan Carlos, Juan G. Abraldes, and Jaume Bosch. "Transjugular Intrahepatic Portosystemic Shunt." In Urgent Interventional Therapies, 389–402. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118504499.ch45.

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Price, Grant J. "Transjuglar Intrahepatic Portosystemic Shunt." In An Internist’s Illustrated Guide to Gastrointestinal Surgery, 297–307. Totowa, NJ: Humana Press, 2003. http://dx.doi.org/10.1007/978-1-59259-389-7_25.

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Park, Jae Hyung, Joon Koo Han, Jin Wook Chung, and Man Chung Han. "Transjugular Intrahepatic Portosystemic Shunt." In Modern Vascular Surgery, 561–68. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2632-1_60.

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Kissane, Jennifer, Janet A. Neutze, and Harjit Singh. "Transjugular Intrahepatic Portosystemic Shunt." In Radiology Fundamentals, 309–15. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-22173-7_44.

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Conference papers on the topic "Portosystemic"

1

Gadahadh, Ravi. "Management of Pediatric Congenital Portosystemic Shunt." In PAIRS 2022 Annual Congress. Thieme Medical and Scientific Publishers Pvt. Ltd., 2022. http://dx.doi.org/10.1055/s-0042-1756239.

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Saleem, Shadi. "Type II Congenital Portosystemic Shunt: Consideration for Endovascular Closure." In PAIRS Annual Meeting. Thieme Medical and Scientific Publishers Pvt. Ltd., 2019. http://dx.doi.org/10.1055/s-0041-1730612.

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Jarmakani, Maha, Shadi Saleem, and Mahmoud Elkaissi. "Type II Congenital Portosystemic Shunt: Consideration for Endovascular Closure." In Abstracts of 3rd Annual Meeting of the American Society of Digestive Disease Interventions. Thieme Medical Publishers, 2017. http://dx.doi.org/10.1055/s-0037-1603704.

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Olatunde, O., V. V. Tambe, A. Kattamanchi, and V. Jasti. "Clinical Response of Hepatopulmonary Syndrome to Transjugular Intrahepatic Portosystemic Shunting." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5510.

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Jansen, C., P. Philipp Moeller, C. Meyer, CC Kolbe, C. Bogs, A. Pohlmann, R. Schierwagen, et al. "Increase in liver stiffness after transjugular intrahepatic portosystemic shunt predicts mortality." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1605109.

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Müllner-Bucsics, TA, K. Lampichler, C. Vierziger, M. Schoder, F. Wolf, D. Bauer, B. Simbrunner, et al. "Covered transjugular intrahepatic portosystemic shunt improves hypersplenism-associated cytopenia in cirrhosis." In 54. Jahrestagung & 31. Fortbildungskurs der Österreichischen Gesellschaft für Gastroenterologie & Hepatologie – ÖGGH (Hybrid Veranstaltung). Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1734282.

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Bucsics, T., M. Schoder, M. Mandorfer, P. Schwabl, F. Karnel, M. Peck-Radosavljevic, M. Trauner, and T. Reiberger. "Transjugular intrahepatic portosystemic shunt implantation improves renal function in patients with ascites." In 52. Jahrestagung & 30. Fortbildungskurs der Österreichischen Gesellschaft für Gastroenterologie & Hepatologie (ÖGGH). Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1691919.

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Thetford, J., S. Jasuja, and N. Barot. "Improving High Output Heart Failure with Trans-Jugular Intrahepatic Portosystemic Shunt Revision." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7300.

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Utturkar, Atul, and Shadi Saleem. "Revision of a Transjugular Intrahepatic Portosystemic Shunt Using a Percutaneous Transhepatic Approach." In 4th Annual Meeting of the American Society of Digestive Disease Interventions. Thieme Medical Publishers, 2017. http://dx.doi.org/10.1055/s-0038-1641630.

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Ju, Connie, Wendy Coronado, and Baljendra Kapoor. "Predictors and Management of Hepatic Encephalopathy in Patients with Transjugular Intrahepatic Portosystemic Shunt." In Abstracts of 5th Annual Meeting of the American Society of Digestive Disease Interventions. Thieme Medical Publishers, 2019. http://dx.doi.org/10.1055/s-0039-1679912.

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Reports on the topic "Portosystemic"

1

Hu, Yang Yang, Xing Zhang, Yue Luo, and Yadong Wang. Systematic review and Meta analysis of the efficacy and safety of rifaximin in the prevention and treatment of hepatic encephalopathy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2023. http://dx.doi.org/10.37766/inplasy2023.2.0061.

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Review question / Objective: P：Liver cirrhosis patients with risk factors associated with HE attack;HE patients caused by chronic liver diseases represented by cirrhosis. I: Rifaximin treatment. C: Other drugs or placebo. O：HE incidence; HE improvement; All-cause mortality; Blood ammonia level; PSE index; mental state; NCT-A; NCT-B; Adverse events. Condition being studied: Hepatic encephalopathy(HE) is a neuropsychiatric disorder syndrome based on metabolic disorders, which is caused by severe acute and chronic liver dysfunction or various abnormalities of portosystemic shunt (hereinafter referred to as portosystemic shunt). The research data shows that the prevalence of OHE in patients with cirrhosis is 10-14%, and the prevalence of HE in patients with decompensated cirrhosis is 16-21%. HE can lead to 60-80% of patients with liver cirrhosis with mild cognitive impairment, affecting their ability of daily life and quality of life. When OHE occurs, the one-year mortality rate of patients with liver cirrhosis is 64%, which brings a heavy economic burden to patients and public health resources. Therefore, the prevention and early management of HE is very important.
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Yang, Ming, Youwei Wu, Yiwen Qiu, and Wentao Wang. Comparision between Transjugular Intrahepatic Portosystemic Shunt and Endoscopic Therapy for Prevention of Variceal Re-bleeding: A Meta-Analysis of Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0142.

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Review question / Objective: The efficacy and safety of placement of transjugular intrahepatic portosystemic shunts (TIPS) in patients with cirrhosis and acute variceal bleeding is controversial. Eligibility criteria: (1) RCTs that compared TIPS and ET for the prevention of variceal rebleeding in patients with cirrhosis; (2) TIPS and ET (EVL or injection therapy) were after randomization; (3) patients in the included studies were aged 18 years old or older; (4) The prognosis that assessed the effects of treatments included at least one of the following outcomes: the overall mortality, the rate of variceal re-bleeding, the incidence of postoperative HE, and new or worsening ascites.
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