Academic literature on the topic 'Positive chemotaxis'

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Journal articles on the topic "Positive chemotaxis"

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Kim, Hye-Eun, Maiko Shitashiro, Akio Kuroda, Noboru Takiguchi, Hisao Ohtake, and Junichi Kato. "Identification and Characterization of the Chemotactic Transducer in Pseudomonas aeruginosa PAO1 for Positive Chemotaxis to Trichloroethylene." Journal of Bacteriology 188, no. 18 (2006): 6700–6702. http://dx.doi.org/10.1128/jb.00584-06.

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ABSTRACT Pseudomonas aeruginosa PAO1 is repelled by trichloroethylene (TCE), and the methyl-accepting chemotaxis proteins PctA, PctB, and PctC serve as the major chemoreceptors for negative chemotaxis to TCE. In this study, we found that the pctABC triple mutant of P. aeruginosa PAO1 was attracted by TCE. Chemotaxis assays of a set of mutants containing deletions in 26 potential mcp genes revealed that mcpA (PA0180) is the chemoreceptor for positive chemotaxis to TCE. McpA also detects tetrachloroethylene and dichloroethylene isomers as attractants.
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Pestonjamasp, Kersi N., Carol Forster, Chunxiang Sun, et al. "Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis." Blood 108, no. 8 (2006): 2814–20. http://dx.doi.org/10.1182/blood-2006-01-010363.

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Abstract Chemotactic responsiveness is crucial to neutrophil recruitment to sites of infection. During chemotaxis, highly divergent cytoskeletal programs are executed at the leading and trailing edge of motile neutrophils. The Rho family of small GTPases plays a critical role in cell migration, and recent work has focused on elucidating the specific roles played by Rac1, Rac2, Cdc42, and Rho during cellular chemotaxis. Rac GTPases regulate actin polymerization and extension of the leading edge, whereas Rho GTPases control myosin-based contraction of the trailing edge. Rac and Rho signaling are thought to crosstalk with one another, and previous research has focused on mutual inhibition of Rac and Rho signaling during chemotaxis. Indeed, polarization of neutrophils has been proposed to involve the activity of a negative feedback system where Rac activation at the front of the cell inhibits local Rho activation, and vice versa. Using primary human neutrophils and neutrophils derived from a Rac1/Rac2-null transgenic mouse model, we demonstrate here that Rac1 (and not Rac2) is essential for Rho and myosin activation at the trailing edge to regulate uropod function. We conclude that Rac plays both positive and negative roles in the organization of the Rhomyosin “backness” program, thereby promoting stable polarity in chemotaxing neutrophils.
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Somasundar, Ambika, Subhadip Ghosh, Farzad Mohajerani, et al. "Positive and negative chemotaxis of enzyme-coated liposome motors." Nature Nanotechnology 14, no. 12 (2019): 1129–34. http://dx.doi.org/10.1038/s41565-019-0578-8.

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Senba, Takasi, and Takasi Suzuki. "A quasi-linear parabolic system of chemotaxis." Abstract and Applied Analysis 2006 (2006): 1–21. http://dx.doi.org/10.1155/aaa/2006/23061.

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We consider a quasi-linear parabolic system with respect to unknown functionsuandvon a bounded domain ofn-dimensional Euclidean space. We assume that the diffusion coefficient ofuis a positive smooth functionA(u), and that the diffusion coefficient ofvis a positive constant. IfA(u)is a positive constant, the system is referred to as so-called Keller-Segel system. In the case where the domain is a bounded domain of two-dimensional Euclidean space, it is shown that some solutions to Keller-Segel system blow up in finite time. In three and more dimensional cases, it is shown that solutions to so-called Nagai system blow up in finite time. Nagai system is introduced by Nagai. The diffusion coefficients of Nagai system are positive constants. In this paper, we describe that solutions to the quasi-linear parabolic system exist globally in time, if the positive functionA(u)rapidly increases with respect tou.
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Sampedro, Inmaculada, Daniel Pérez-Mendoza, Laura Toral, Esther Palacios, César Arriagada, and Inmaculada Llamas. "Effects of Halophyte Root Exudates and Their Components on Chemotaxis, Biofilm Formation and Colonization of the Halophilic Bacterium Halomonas Anticariensis FP35T." Microorganisms 8, no. 4 (2020): 575. http://dx.doi.org/10.3390/microorganisms8040575.

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Increase in soil salinity poses an enormous problem for agriculture and highlights the need for sustainable crop production solutions. Plant growth-promoting bacteria can be used to boost the growth of halophytes in saline soils. Salicornia is considered to be a promising salt-accumulating halophyte for capturing large amounts of carbon from the atmosphere. In addition, colonization and chemotaxis could play an important role in Salicornia-microbe interactions. In this study, the role of chemotaxis in the colonization of the halophilic siredophore-producing bacteria, Halomonas anticariensis FP35T, on Salicornia hispanica plants was investigated. The chemotactic response of FP35T to Salicornia root exudates showed optimum dependence at a salt concentration of 5 % NaCl (w/v). Oleanolic acid, the predominant compound in the exudates detected by HPLC and identified by UPLC-HRMS Q-TOF, acts as a chemoattractant. In vitro experiments demonstrated the enhanced positive effects of wild-type H. anticariensis strain FP35T on root length, shoot length, germination and the vigour index of S. hispanica. Furthermore, these positive effects partially depend on an active chemotaxis system, as the chemotaxis mutant H. anticariensis FP35 ΔcheA showed reduced plant growth promotion for all the parameters tested. Overall, our results suggest that chemotaxis responses to root exudates play an important role in interactions between Salicornia and halophilic bacteria, enhance their colonization and boost plant growth promotion. Preliminary results also indicate that root exudates have a positive impact on H. anticariensis FP35T biofilm formation under saline conditions, an effect which totally depends on the presence of the cheA gene.
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Sly, Laura M., Elizabeth A. Worobec, Richard E. Perkins, and Paul V. Phibbs Jr. "Reconstitution of glucose uptake and chemotaxis in Pseudomonas aeruginosa glucose transport defective mutants." Canadian Journal of Microbiology 39, no. 11 (1993): 1079–83. http://dx.doi.org/10.1139/m93-163.

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Wild-type glucose uptake and glucose chemotaxis activities were restored in glucose transport defective Pseudomonas aeruginosa strains PFB360 and PFB362 after introduction of plasmid pPZ129, containing a 1.1-kilobase DNA fragment that is essential for the expression of the P. aeruginosa periplasmic glucose binding protein. The restoration of glucose uptake and chemotaxis to wild-type levels in these strains was also achieved by reconstitution with cold-shock fluid and purified glucose binding protein isolated from P. aeruginosa PA01 wild-type strain H103 grown in conditions resulting in the induction of the high-affinity glucose transport system. Glucose uptake was determined by whole cell uptake and shock fluid binding of D-[U-14C]glucose, using standard filter binding assays. Positive chemotaxis towards glucose was assessed by capillary assays using 10 mM glucose, the amount required for optimal chemotaxis, and judged by plating capillary contents accumulated after 30 min.Key words: glucose-binding protein, Pseudomonas aeruginosa, glucose transport, chemotaxis.
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ZHU, MEI, and J. D. MURRAY. "PARAMETER DOMAINS FOR GENERATING SPATIAL PATTERN: A COMPARISON OF REACTION–DIFFUSION AND CELL-CHEMOTAXIS MODELS." International Journal of Bifurcation and Chaos 05, no. 06 (1995): 1503–24. http://dx.doi.org/10.1142/s0218127495001150.

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Reaction–diffusion and cell-chemotaxis mechanisms have been widely used as models for biological pattern formation. Applications require the formation of specific patterns. Both mechanisms involve local reaction dynamics and diffusion. In addition, the cell-chemotaxis mechanism involves chemotactic movement in response to an external gradient. It has been considered that chemotaxis is like negative diffusion which has a destabilizing effect. In this paper, we use a general weakly nonlinear analysis and numerical simulations to divide the parameter space into different domains giving rise to specific classes of spatial patterns, namely, spots and stripes, compare the robustness and sensitivity of the different models, and discuss spatial patterns intermediate between stripes and spots. We show that chemotaxis is not always a destabilizing factor — it can also have positive diffusion effect.
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Melnichuk, T. N. "THE RHIZOBACTERIA CHEMOTAXIS TO EXUDATION OF VEGETABLE PLANTS ON MEDIUM WITH AGAR." Agriciltural microbiology 7 (October 23, 2008): 21–28. http://dx.doi.org/10.35868/1997-3004.7.21-28.

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The modified method of positive chemotaxis determination at the culture of rhizobakteria to vegetable plant exudates on the medium with agar was proposed. It is a substitution of artificial introduction of chemoeffectors with native exudates of seedlings of the definite plants which are a complex of compounds. This method provides determination of positive chemotaxis (the initial stage of plants-microbes associations forming), allows to explain the promoted activity of strains at their application in microbic complexes and it is considered to be perspective for initial evaluation of new and industrial strains.
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Vangnai, Alisa S., Kazuki Takeuchi, Shota Oku, et al. "Identification of CtpL as a Chromosomally Encoded Chemoreceptor for 4-Chloroaniline and Catechol in Pseudomonas aeruginosa PAO1." Applied and Environmental Microbiology 79, no. 23 (2013): 7241–48. http://dx.doi.org/10.1128/aem.02428-13.

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ABSTRACTBacterial chemotaxis influences the ability of bacteria to survive and thrive in most environments, including polluted ones. Despite numerous reports of the phenotypic characterization of chemotactic bacteria, only a few molecular details of chemoreceptors for aromatic pollutants have been described. In this study, the molecular basis of chemotaxis toward an environmentally toxic chlorinated aromatic pollutant, 4-chloroaniline (4CA), was evaluated. Among the threePseudomonasspp. tested,Pseudomonas aeruginosaPAO1 exhibited positive chemotaxis both to the nonmetabolizable 4CA, where 4-chloroacetanilide was formed as a dead-end transformation product, and to the metabolizable catechol. Molecular analysis of all 26 mutants with a disrupted methyl-accepting chemotaxis gene revealed that CtpL, a chromosomally encoded chemoreceptor, was responsible for the positive chemotactic response toward 4CA. Since CtpL has previously been described to be a major chemoreceptor for inorganic phosphate at low concentrations in PAO1, this report describes a fortuitous ability of CtpL to function toward aromatic pollutants. In addition, its regulation not only was dependent on the presence of the chemoattractant inducer but also was regulated by conditions of phosphate starvation. These results expand the range of known chemotactic transducers and their function in the environmental bacterium PAO1.
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Shi, Wenyuan, Zhaomin Yang, Yongzhi Geng, Lawrence E. Wolinsky, and Michael A. Lovett. "Chemotaxis in Borrelia burgdorferi." Journal of Bacteriology 180, no. 2 (1998): 231–35. http://dx.doi.org/10.1128/jb.180.2.231-235.1998.

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ABSTRACT Borrelia burgdorferi is a motile spirochete which has been identified as the causative microorganism in Lyme disease. The physiological functions which govern the motility of this organism have not been elucidated. In this study, we found that motility of B. burgdorferi required an environment similar to interstitial fluid (e.g., pH 7.6 and 0.15 M NaCl). Several methods were used to detect and measure chemotaxis of B. burgdorferi. A number of chemical compounds and mixtures were surveyed for the ability to induce positive and negative chemotaxis of B. burgdorferi. Rabbit serum was found to be an attractant for B. burgdorferi, while ethanol and butanol were found to be repellents. Unlike some free-living spirochetes (e.g., Spirochaeta aurantia), B. burgdorferi did not exhibit any observable chemotaxis to common sugars or amino acids. A method was developed to produce spirochete cells with a self-entangled end. These cells enabled us to study the rotation of a single flagellar bundle in response to chemoattractants or repellents. The study shows that the frequency and duration for pausing of flagella are important for chemotaxis of B. burgdorferi.
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Dissertations / Theses on the topic "Positive chemotaxis"

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Sharma, Ved Prakash. "Phospholipid signaling in neutrophil chemotaxis evidence of a positive feedback loop /." [Gainesville, Fla.] : University of Florida, 2007. http://purl.fcla.edu/fcla/etd/UFE0021423.

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Müller, Nadja. "Generierung und Evaluation von modifizierten NK-Zellen mit SDF-1alpha-Chemotaxis und Reaktivität gegen EGFRvIII-positive Gliomzellen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-149550.

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Die vorliegende Arbeit beinhaltet die Generierung und Evaluation von Natürlichen Killerzellen, die EGFRvIII-positive und SDF-1alpha sekretierende primäre Glioblastomzellen aufspüren, erkennen und effizient abtöten können. Die Kombination der gelenkten Zytotoxizität mit einer optimierten Migration von Effektorzellen des Immunsystems wird auf Grundlage der in dieser Arbeit gewonnenen Daten als ein vielversprechender Ansatz für eine zukünftige Therapie des primären Glioblastoms vorgeschlagen.
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Müller, Nadja [Verfasser], Hanns Achim [Akademischer Betreuer] Temme, and Günter [Akademischer Betreuer] Vollmer. "Generierung und Evaluation von modifizierten NK-Zellen mit SDF-1alpha-Chemotaxis und Reaktivität gegen EGFRvIII-positive Gliomzellen / Nadja Müller. Gutachter: Hanns Achim Temme ; Günter Vollmer. Betreuer: Hanns Achim Temme." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://d-nb.info/1068447826/34.

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Book chapters on the topic "Positive chemotaxis"

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Gooch, Jan W. "Positive Chemotaxis." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_14545.

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Ordal, George W., Leticia Màrquez-Magaña, and Michael J. Chamberlin. "Motility and Chemotaxis." In Bacillus subtilis and Other Gram-Positive Bacteria. ASM Press, 2014. http://dx.doi.org/10.1128/9781555818388.ch53.

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Tian, Ya, and Guoqing Xie. "Boundedness of Solutions for Indirect Chemotaxis Model with Diffusion-Dependent Signal Concentration." In Fuzzy Systems and Data Mining IX. IOS Press, 2023. http://dx.doi.org/10.3233/faia231073.

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This work establishes an indirect chemotaxis model with diffusion-dependent signal concentration { ut = Δ(uγ(v)), vt = Δv – v + w, wt = Δw – w + u for all (x,t) ∈ Ω × (0,∞), in a smooth bounded domain Ω ⊂ ℝ2 under the homogeneous second boundary condition, and the positive function γ fulfills assumptions: γ(s) ∈ C3([0,∞)) and γ′(s) ≤ 0 (∀s > 0). By some prior estimation, the boundedness of solutions can be obtained from this model.
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Lynch, Michael R. "Environmental Sensing." In Evolutionary Cell Biology. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/oso/9780192847287.003.0022.

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Abstract Unicellular organisms use signal transduction (ST) systems to sense external environmental stimuli and relay information to internal regulators of intracellular responses, chemotaxis being one such example. Most ST systems operate via additions and removals of phosphoryl groups on the participating proteins. Substitutions of just a few amino-acid residues are often sufficient to alter the mode of intermolecular communication, providing a potential means for the origin of new systems as well as the neutral drift of pre-existing systems. Bacterial ST systems are typically quite simple and modular in nature, relying on pairs of sensor and regulator proteins whose crosstalk is insulated from other such pairs; in most species, dozens to hundreds of such systems are specialized to sensing different environmental stimuli. The maintenance of ST systems in states of readiness entails a considerable cost in terms of recurrent ATP expenditure. Although the underlying participants operate as conventional Michaelis–Menten enzymes, the pathways are structured in ways that can generate very steep responses to external signal concentrations, in some cases allowing for near switch-like behavior in downstream responses. With certain kinds of positive-feedback loops included, such systems can lead to semi-stable bimodal phenotype distributions among otherwise genetically uniform cells. This may be either advantageous or maladaptive depending on the environmental context. Eukaryotic ST systems tend to be much more complicated than those in bacteria, commonly involving cascades of multiple intermediate steps, and with considerable crosstalk among different partners. It remains unclear whether this added complexity has been driven by adaptive or nonadaptive forces peculiar to multicellular species.
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Conference papers on the topic "Positive chemotaxis"

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Nestoridis, Theodoros, Konstantinos Kantelis, Stathis Mavridopoulos, Georgios Papadimitriou, and Petros Nicopolitidis. "Directional transmission in biological nanonetworks via positive Chemotaxis." In NANOCOM '19: The Sixth Annual ACM International Conference on Nanoscale Computing and Communication. ACM, 2019. http://dx.doi.org/10.1145/3345312.3345491.

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Hoshikawa, N., H. Niino, J. Imura, Y. Ashihara, and K. Shirasawa. "CHEMOTAXIS OF POLYMORPHONUCLEAR LEUKOCYTES BY VASCULAR PERMEABILITY FACTOR FROM BOVINE PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643164.

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Bovine platelet a-granule acid extract (BPAE) contains vascular permeability factor (VPF) as human platelets. VPF plays as a mediator depending on polymorphonuclear (PMN) leukocytes and possesses a potent cell growth activity in cultured fibroblasts. This study was carried out to examine the chemotactic activity of VPF for PMN leukocytes of rabbits. For the study of chemotaxis, the PMN leukocytes were collected from the ascites after production by an injection of 0.1% oyster glycogen in 0.85% NaCl solution into the peritoneal cavity of rabbits. They were suspended in the Gey's balanced salt solution with supplementation of 2% human albumin. Partial purification of BPAE was performed by gel filteration using Sephadex G-50 so as to exclude the influence of PF-4 and 8-TG. BPAE, as the attractant solution, was prepared at the several concentration in the Gey's solution. Human serum activated with zymosan was used as the positive control. Effects of protamine sulfate, a competitive inhibitor of platelet-derived growth factor (PDGF), on the chemotactic activity of VPF were also studied. Chemotaxis of the PMN leukocytes was measured in the modified Boyden chamber with a 3jJm-pore filter. Five high power (x400) grids were counted per filter and cell migration was corrected by subtraction of blanks in which the lower compartment contained medium only. The most striking chemotactic response was obtained when BPAE was used at the concentration of 0.1μg/ml. However, the response was reduced at the concentration of more than 1μg/ml. The activity of BPAE (0.1μg/ml) was about 60% of the positive control level. The migration was reduced to 18% of the positive control by protamine sulfate (3μg/ml) at that concentration of BPAEIt is concluded that VPF induces chemotaxis to PMN leukocytes at the concentration lesser than that enhancing the vascular permeability response. Furthermore, protamine sulfate inhibits the VPF-induced migration of PMN leukocytes. Those findings may indicate that VPF acts as PDGF in function. Therefore, it is likely that the factor attracts PMN leukocytes and promotes cell growth in the inflamed region
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Braun, Rhea, Maxwell Tfirn, and Roseanne Ford. "Sonification of Chemotactic Waves of Bacteria." In ICAD 2023: The 28th International Conference on Auditory Display. International Community for Auditory Display, 2023. http://dx.doi.org/10.21785/icad2023.8263.

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Chemotaxis is the ability of certain microscopic organisms to sense and swim towards beneficial or away from detrimental chemicals in their surroundings. Identifying this behavior is important for understanding the relationships between species and their environments in the natural world. Predicting migration of an entire population from known characteristics of individual microorganisms is a key contribution, but can be a laborious process and requires watching and waiting for visual evidence of the process on a large population scale. Sonification offers a novel solution to this problem by allowing the observer to tap into our auditory sensory system to process information. In this project, we developed and assessed a proof-of-concept sonification tool as a high throughput, real-time screening tool for chemotaxis in populations of swimming bacteria. The tool operates by reporting the y-axis position of bacteria that appear in the microscope image as microsecond duration pitched notes, giving the user a sense of the average location of the population. In this paper, we present how it has been used as a chemotaxis assay and as a tool to locate traveling waves of bacteria as they pass through the field of view in order to capture data at specific timepoints, which is used to analyze individual swimming patterns of microorganisms within the wave.
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Guzma´n Pardo, Maria Alejandra, Rodrigo Nicoletti, and Jonas de Carvalho. "Shaft Shape Multi Objective Optimization Based on Bacterial Chemotaxis." In ASME Turbo Expo 2010: Power for Land, Sea, and Air. ASMEDC, 2010. http://dx.doi.org/10.1115/gt2010-23359.

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Chemotaxis is the biased movement developed by certain living organisms as a response to chemical gradients present in their environment. Thanks to advances in the computing field, bacterial chemotactical strategies and its excellent ability in searching can be modeled, simulated and emulated, thus developing bio-inspired optimization methods alternatively to classical methods. In this work, a multi objective optimization algorithm based on bacterial chemotaxis is proposed and applied to the shape optimization of shafts. Design variables are the diameters along shaft’s length and different constraints are tested, such as variable torques, critical velocities, and position of elements. The design results are obtained in terms of final weight and design safety factors at specific points of the shaft, thus leading to a front of optimum solutions, i.e. to the different possible design solutions that satisfy design constraints, where the engineer can find the best compromise solution for his application.
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