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Dissertations / Theses on the topic 'Positive inotrope'

Author: Grafiati
Published: 4 June 2021
Last updated: 10 March 2023

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1

Weintraub, Joe͏̈lle. "Les hétérosides cardiotoniques : propriétés pharmacologiques et mécanisme de leur action inotrope positive." Paris 5, 1988. http://www.theses.fr/1988PA05P057.

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2

Chamberland, Caroline. "Action inotrope positive de l'apéline liée à l'augmentation de l'amplitude du courant sodique dans les myocytes cardiaque de chien." Mémoire, Université de Sherbrooke, 2008. http://savoirs.usherbrooke.ca/handle/11143/3965.

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L'apéline est l'agoniste du récepteur APJ-R (putative angiotensin II receptor like), récepteur couplé aux protéines G. Exprimée dans le coeur de plusieurs espèces dont l'homme, l'apéline joue un rôle important dans le système cardiovasculaire. L'apéline a un effet inotrope positif sur le coeur. Szokodi et al. ont démontré que cet effet était dû à l'activation de la cascade PLC-PKC et que les échangeurs sodium-hydrogène (NHE) et sodium-calcium (NCX) étaient impliqués. Ils ont également démontré que l'augmentation de la force contractile du myocarde n'était pas due à l'augmentation du courant ca
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3

ALEMANNI, MATTEO. "The modulation of SERCA pump activity as a tool for management of hearth failure." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/7462.

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The current positive inotropic interventions for the management of heart failure (HF) are all associated to an unchanged or increased long term mortality, which limit their use. Istaroxime (IST) is a novel positive inotrope able to inhibit Na+, K+ ATPase and to stimulate SERCA pump. We employed IST as a tool to assess the role of a mild SERCA stimulation as a positive inotropic intervention. In a guinea pig model of HF, where the sarcoplasmic reticulum (SR) function was deranged, IST was able to restore an optimal SR function, increase the SR Ca2+ content and to improve all the EC coupling par
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4

Razafinjatovo, Jean-Jacques. "Inhibiteurs de phosphodiestérases et autres inotropes positifs apparentes." Strasbourg 1, 1988. http://www.theses.fr/1988STR15067.

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5

Weisselberg, Tilman Wilhelm. "Die Wirkung von Stickstoffmonoxid auf Isoprenalin-induzierte positiv inotrope Effekte beim hypertrophierten Herzen der Ratte." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963216902.

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6

Bell, David. "Receptors for positive inotropic peptides and associated mechanisms of contractile coupling in isolated ventricular cardiomyocytes." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359022.

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7

Quiniou, Gilles. "Les nouveaux inotropes positifs dans le traitement de l'insuffisance cardiaque, à propos d'une étude ouverte au centre hospitalier de la côte basque sur l'Enoxinome oral." Bordeaux 2, 1989. http://www.theses.fr/1989BOR25216.

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8

Marciniak, Gilbert. "Nouveaux heterocycles doues d'activites antiangineuses, inotropes positives ou antagonistes des canaux calciques : synthese, modelisation et relations structure-activite." Université Louis Pasteur (Strasbourg) (1971-2008), 1987. http://www.theses.fr/1987STR13142.

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Recherche par modelisation moleculaire sur ordinateur d'une structure commune a cinq inotrpes positifs connus ; synthese et proprietes pharmacologiques de nouveaux inotropes positifs (pyridyl-quinoles) ; preparation et pharmacologie de composes apparentes a la perhexiline ; synthese et activite biologique de dihydropyridines
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9

Marciniak, Gilbert. "Nouveaux hétérocycles doués d'activités antiangineuses, inotropes positives ou antagonistes des canaux calciques synthèse, modélisation et relations structure-activité /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37607708r.

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10

Kania, Sebastian Martin Albert [Verfasser], Rolf [Akademischer Betreuer] Wachter, Wolfram-Hubertus [Gutachter] Zimmermann, and Wolfgang [Gutachter] Krick. "Der positiv inotrope Effekt von Insulin am menschlichen Myokard / Sebastian Martin Albert Kania. Betreuer: Rolf Wachter. Gutachter: Wolfram-Hubertus Zimmermann ; Wolfgang Krick." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://d-nb.info/1105759962/34.

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11

Geilfus, Diana [Verfasser], and Bernhard [Akademischer Betreuer] Graf. "Direkte kardiale Effekte positiv inotroper Pharmaka bei Sepsis-induzierter kardialer Dysfunktion am isoliert perfundierten Rattenherzen / Diana Geilfus. Gutachter: Bernhard Graf. Betreuer: Bernhard Graf." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2010. http://d-nb.info/1042722390/34.

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12

Ritterhoff, Julia [Verfasser], and Martin [Akademischer Betreuer] Müller. "S100A1 acts positive inotropic and prevents Ca2+ triggered after-contractions in a model of Engineered Heart Tissue / Julia Ritterhoff ; Betreuer: Martin Müller." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/1177809273/34.

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13

Potter, Tetyana [Verfasser]. "Hemmung der Alpha-1-beta-1-Isoform der Na,K-ATPase aber fehlender positiv inotroper Effekt von 8-Methoxycoumestrol im humanen Myokard – neue Aspekte in der Pharmakologie der Herzglykoside / Tetyana Potter." Köln : Deutsche Zentralbibliothek für Medizin, 2010. http://d-nb.info/1007870699/34.

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14

Klenowski, Paul Mark. "Molecular and structural requirements of the ß1L-adrenoceptor." Thesis, Queensland University of Technology, 2012.

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Noradrenaline which occurs naturally in the body binds to beta-adrenoceptors on the heart, causing the heart to beat faster and with greater force in response to increased demand. This enables the heart to provide oxygenated blood to vital organs. Prolonged overstimulation by noradrenaline can be harmful to the heart and lead to the progression of heart disease. In these circumstances beta-adrenoceptors are blocked with drugs called beta-blockers. Beta-blockers block the effects of noradrenaline by binding to the same site on the beta-adrenoceptor. Some beta-blockers such as CGP12177 can also
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15

Christoph, Johannes. "Die Herzfunktion während milder Hypothermie bei anästhesierten Schweinen: gesteigerte Inotropie auf Kosten einer diastolischen Dysfunktion." Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07F-2.

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16

Schoffstall, Brenda. "Modulators of myosin activity and actomyosin interaction potential for 2'-DEOXY-ATP (dATP) as a positive inotrope in cardiac muscle /." 2006. http://etd.lib.fsu.edu/theses/available/etd-10272006-190157/.

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Thesis (Ph. D.)--Florida State University, 2006.<br>Advisor: P. Bryant Chase, Florida State University, College of Arts and Sciences, Institute of Molecular Biophysics. Title and description from dissertation home page (viewed May 9, 2007). Document formatted into pages; contains xvi, 168 pages. Includes bibliographical references.
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17

CHANG, GWO-JYH, and 張國志. "MECHANISMS FOR THE POSITIVE INOTROPY AND ANTIARRHYTHMIC ACTION." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/75934889446371021452.

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博士<br>國立臺灣大學<br>藥理學研究所<br>85<br>The mechanisms of the positive inotropic action of a new synthetictetrahydroisoquinoline compound, SL-1, were investigated in isolated ratcardiac tissues and ventricular myocytes. SL-1 (3-300 ? M) produced a rapidlydeveloping, concentration-dependent positive inotropic response in both atrialand ventricular muscles and a negative chronotropic effect in spontaneouslybeating right atria. The positive inotropic effect was not prevented bypretreatment with reserp
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18

Kania, Sebastian Martin Albert. "Der positiv inotrope Effekt von Insulin am menschlichen Myokard." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-8773-0.

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19

Geilfus, Diana. "Direkte kardiale Effekte positiv inotroper Pharmaka bei Sepsis-induzierter kardialer Dysfunktion am isoliert perfundierten Rattenherzen." Doctoral thesis, 2010. http://hdl.handle.net/11858/00-1735-0000-0006-AF7F-4.

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20

Weißelberg, Tilman Wilhelm [Verfasser]. "Die Wirkung von Stickstoffmonoxid auf Isoprenalin-induzierte positiv inotrope Effekte beim hypertrophierten Herzen der Ratte / von Tilman Wilhelm Weißelberg." 2001. http://d-nb.info/963216902/34.

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21

Sabatschus, Ingo. "Verminderung des b-adrenergen [Beta-adrenergen] positiv inotropen Effekts im atrialen Myokard von Patienten mit Vorhofflimmern /." 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014578734&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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22

Dincer, Deniz [Verfasser]. "Effektivität von positiv inotropen Substanzen am Vorhofsmyokard von Patienten mit chronischem Vorhofflimmern / vorgelegt von Deniz Dincer." 2007. http://d-nb.info/984921648/34.

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23

Mahnecke, Nina [Verfasser]. "Bedeutung der Myosin-Leichtketten-Kinase für den alpha1-adrenergen positiv inotropen Effekt im Herzmuskel / vorgelegt von Nina Mahnecke." 2008. http://d-nb.info/991706714/34.

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