Academic literature on the topic 'Post-extraction complications'

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Journal articles on the topic "Post-extraction complications"

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Saravanan, Keerthika. "Assessment of post extraction complications in Indians." Bioinformation 17, no. 12 (2021): 1120–25. http://dx.doi.org/10.6026/973206300171120.

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Extraction is one of the commonest procedures in dentistry. Therefore, it is of interest to evaluate the post extraction complications in patients undergoing extractions of permanent teeth. A total of 70 adult patients who had undergone dental extractions and presented with post -operative complications were included in the study and evaluated. Data collected was statistically analyzed using SPSS software and results obtained. Most of the patients with post extraction complications were in the age group of 31-40 years (21.6%), followed by 21-30 (20.2%) and 61-70 years (20.2%). Dry socket (39.19%) was the common post extraction complication in our study especially in the age group of 31-40 years. There was a statistically significant association between age of the patients and the post extraction complications (p<0.001). In our study, post extraction complications were commonly observed in age group of 31-40 years with a predilection for males. Dry socket was the most common post extraction complication. Age of the patient has a significant effect on post extraction complications. However, gender, smoking habits and systemic diseases have no influence on post extraction complications.
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Md Sohaib Shahzan and Madhulaxmi Marimuthu. "Post extraction complications - An institution based retrospective study." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 1970–74. http://dx.doi.org/10.26452/ijrps.v11ispl3.3701.

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Tooth extraction is one of the most common procedures undertaken in the dental clinic. As with any surgical procedure, even a simple tooth extraction can result in complications. Post extraction complications can be annoying to the patient, thereby causing mild morbidity and have an impact on their quality of life. Complications are wide starting from common ones like alveolitis and root fracture, dry socket, infraction, halitosis, pain, trismus and uncommon ones like displacement of root fragments within the sinus and oral antral fistula. The aim of this study was to evaluate post-extraction complications among patients visiting saveetha dental college. This is a retrospective study. We reviewed patient records and analysed the data of 86000 patients between June 2019 and March 2020. From a pooled sample size of 23000 extractions done during this period, data of patients reporting for post-extraction complications were segregated and analysed. The statistical analysis was done using SPSS Version 20 by IBM. The results were analysed using the chi-square test. In this study, we observed that among a sample of 23000 simple extractions, only 42 patients had reported back with post-extraction complications (0.18%). These complications were more in males than in females. When compared between maxillary and mandibular arch, the mandible had more incidence with 54.16%. The most common complication was dry socket (58.34%). Pain as a complication was more in males than in females. Within the limits of the study, the incidence of post-extraction complication is more in males than females. Higher incidence of complication was seen in a mandibular arch (54.16%) than in maxillary arch (45.84%).
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Assiry, Muad, Mohammed Aloqbi, Hassan Albrahim, et al. "Prevalence and Management of Post-Extraction Complications." Journal of Complementary Medicine Research 14, no. 2 (2023): 90. http://dx.doi.org/10.5455/jcmr.2023.14.02.14.

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Introduction: Simple tooth extraction is one of the most common procedures performed by general dentists and Oral and Maxillofacial surgeons throughout daily practice. However, although it is a simple procedure, tooth-related complications could occur at any time. These complications are categorized into immediate and delayed complications. Immediate complications are due to either tooth-related or dentist-related factors and require prompt actions and immediate management. Tooth-related factors depend on tooth morphology and tooth structure conditions. Dentist-related factors depend on the proper selection and application of the instruments. On the other hand, delayed complications might occur after two days or more following the extraction. Objective: To evaluate the prevalence, prediction of risk factors complications, prevention and management of possible immediate and delayed post-extraction complications occurring in our Oral Surgery clinics at King Abdulaziz University Dental Hospital. Method: An observation and assessment of the extraction procedure, data collected via validated survey were used to gather the following: Demographic data, medical history, cause of extraction, number of tooth/teeth extracted, complications if any, and who did the procedure. For each patient who underwent dental extraction, a survey was filled out, by a doctor other than the operator and the procedure was assessed under observation to record any complications that occurred during the procedure and assess the undertaken management in such a case without intervention. Data was analyzed using Chi-square test through SPSS. Result: We observed 172 extraction procedures with 160 different patients, 12 had extraction more than once. A total 350 teeth were extracted from 160 patients, we observed 92 complications (53.4%) between immediate and delayed, 7 patients had both, the most common immediate complication was soft tissue injury with (81.7%) 67/82, and for the delayed complications the most common was dry socket (64.7%) 11/17 patients. Conclusion: In conclusion, we found a significant association between the number of post-operative complications, their management, and the experience of the operator
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Stewart, Matthew, Emily Levey, and Namita Nayyer. "Salt water mouthwash post extraction reduced post operative complications." Evidence-Based Dentistry 16, no. 1 (2015): 27–28. http://dx.doi.org/10.1038/sj.ebd.6401084.

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Anjum, Patan, K. V. N. R. Pratap, T. Madhavi Padma, V. Siva Kalyan, and V. Srujan Kumar. "POST EXTRACTION COMPLICATIONS AND MANAGEMENT- KNOWLEDGE BASED STUDY AMONG UNDERGRADUATE DENTAL STUDENTS IN KHAMMAM, TELANGANA." International Journal of Advanced Research 12, no. 12 (2024): 891–95. https://doi.org/10.21474/ijar01/20094.

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Background: Complications following exodontia is not always avoidable. So, dentists should be aware about the treatment to manage complications following exodontia. Hence, it is necessary to ascertain dental students knowledge and attitude towards post extraction complications and its management. Aim: To assess the knowledge regarding post extraction complications and its management among dental students in Khammam, Telangana. Material and Method: Among 150 undergraduate (clinical) students a cross-sectional questionnaire survey was conducted in a tertiary care teaching dental hospital. The sample consists of 87 final years and 63 interns. They were asked to fill a questionnaire which was sent to their mobiles through google link which consists of 20 questions regarding knowledge and attitude about post extraction complications. Result and Conclusion: Majority of dental students have good quality of knowledge towards post extraction complications. Both the final years and interns have almost equal knowledge regarding post extraction complications. Although dental students have good quality of knowledge towards post extraction complications it is not adequate to manage some rare complications. So, there it is necessary to upgrade their knowledge. The need for this study is if the complications of post extractions are not treated properly it might lead to furthermorelife-threatening complications such as morbidity and death. So it is important for a dental to have an adequate idea and knowledge regarding post extraction complications including some rare complications along with its management.
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Madhuluxmi, Madhuluxmi. "The link between gender and post-extraction complications of teeth." Bioinformation 16, no. 12 (2020): 1128–33. http://dx.doi.org/10.6026/973206300161128.

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Extraction of teeth is a common procedure in dentistry. Recalling patients for monitoring wound healing is a concern in surgical procedures. It allows foreseeing signs or/and symptoms possibly related to surgical complications. Therefore, it is of interest to document the link between gender and complications in post extraction. The null hypothesis was age and gender had no impact on post dental extraction. We used patient records at Saveetha Dental College, India for this study. The overall follow-up rate post-extraction is less compared to known literature. Data shows that males outnumbered the females and those “above 40 years” than “below 40 years” in follow-up. Thus, we report that factors such as gender, age and the presence of a post-operative complication play a key role in determining whether a patient reports back for follow-up after routine extractions.
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Madhuluxmi, Madhuluxmi. "The link between gender and post-extraction complications of teeth." Bioinformation 16, no. 12 (2020): 1128–33. http://dx.doi.org/10.6026/973206300161128.

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Extraction of teeth is a common procedure in dentistry. Recalling patients for monitoring wound healing is a concern in surgical procedures. It allows foreseeing signs or/and symptoms possibly related to surgical complications. Therefore, it is of interest to document the link between gender and complications in post extraction. The null hypothesis was age and gender had no impact on post dental extraction. We used patient records at Saveetha Dental College, India for this study. The overall follow-up rate post-extraction is less compared to known literature. Data shows that males outnumbered the females and those “above 40 years” than “below 40 years” in follow-up. Thus, we report that factors such as gender, age and the presence of a post-operative complication play a key role in determining whether a patient reports back for follow-up after routine extractions.
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Budacu, Cristian Constantin, Gheorghe Raftu, Mihaela Debita, Oana Ciurcanu, and Constantin Mihai. "Current Guidance for Postextractional Hemmoragic Prophylaxis and Treatment." Revista de Chimie 70, no. 4 (2019): 1381–84. http://dx.doi.org/10.37358/rc.19.4.7132.

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Post-operative bleeding is a topical issue in dental practice, fact reflected by the etiopathogenic, morpho pathological and therapeutic aspects; may occur at any time as a complication of dental extraction, due to local factors or general factors. The peculiarity of the dental extraction complication lies in the fact that the physician must immediately resort to firm measures leading to its solving in the shortest while, the most prolonged bleeding can put the patient�s life at risk. Therefore surgery must be justified and applied only when the noticing methods are not effective.Knowing the pathology of the patient and its medication are of major importance in order to prevent post-operative hemorrhage complications. Dental extraction is the most frequent intervention of oral surgery that is addressed to both the dentist and the dento-alveolar surgeon, and is performed almost daily in the surgery.One of the local complications of dental extraction is post-surgical hemorrhage. Establishing a therapeutic, prophylactic and curative plan for this complication by conducting a good history of the patient accompanied by paraclinical examinations, the use of a well-established surgical technique can prevent post- operative hemorrhagic complications. The statistical survey was conducted between 2015 -2017; performed on a group of 225 patients. Knowing the methods of prophylaxis and treatment for post-operative bleeding, as well as the correct diagnosis of its causes are mandatory for every practitioner. Post-operative hemorrhage is a complication that can be prevented by making a correct and complete anamnesis, having as its etiology local causes (the most common) or general causes.
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Dua, Piyush, Lengam Tabing, Debleena Sarkar, Muskan Grover, and Aviral Verma. "Liver Clot: The Rare Post-Extraction Complication Striking within 72 Hours." EAS Journal of Medicine and Surgery 6, no. 07 (2024): 219–23. http://dx.doi.org/10.36349/easjms.2024.v06i07.002.

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Oral and Maxillofacial Surgeons may encounter complications while performing major as well as minor surgical procedures, either intraoperatively or postoperatively. Bleeding after a dental extraction is a frequent complication following surgery. This article discusses an uncommon postoperative complication characterized by prolonged bleeding and the formation of a "liver clot" coagulum, observed 72 hours following the extraction of root stump in an elderly female during a follow-up visit.
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Adeyemo, Wasiu Lanre, Akinola Ladipo Ladeinde, and Mobolanle Olugbemiga Ogunlewe. "Clinical Evaluation of Post-Extraction Site Wound Healing." Journal of Contemporary Dental Practice 7, no. 3 (2006): 40–49. http://dx.doi.org/10.5005/jcdp-7-3-40.

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Abstract Aim The aim of this prospective study was to evaluate the clinical pattern of post-extraction wound healing with a view to identify the types, incidence, and pattern of healing complications following non-surgical tooth extraction. Study Design A total of 311 patients, who were referred for non-surgical (intra-alveolar) extractions, were included in the study. The relevant pre-operative information recorded for each patient included age and gender of the patient, indications for extraction, and tooth/teeth removed. Extractions were performed under local anesthesia with dental forceps, elevators, or both. Patients were evaluated on the third and seventh postoperative days for alveolus healing assessment. Data recorded were: biodata, day of presentation for alveolus healing assessment, day of onset of any symptoms, body temperature (°C) in cases of alveolus infection, and presence or absence of pain. Results Two hundred eighty-two patients (282) with 318 extraction sites were evaluated for alveolus healing. Healing was uneventful in 283 alveoli (89%), while 35 alveoli (11%) developed healing complications. These complications were: localized osteitis 26 (8.2%); acutely infected alveolus 5 (1.6%); and an acutely inflamed alveolus 4 (1.2%). Females developed more complications than males (p=0.003). Most complications were found in molars (60%) and premolars (37.1%). Localized osteitis caused severe pain in all cases, while infected and inflamed alveolus caused mild or no pain. Thirty patients (12%) among those without healing complications experienced mild pain. Conclusions Most of the post-extraction alveoli healed uneventfully. Apart from alveolar osteitis (AO), post-extraction alveolus healing was also complicated by acutely infected alveoli and acutely inflamed alveoli. This study also demonstrated a painful alveolus is not necessarily a disturbance of post-extraction site wound healing; a thorough clinical examination must, therefore, be made to exclude any of the complications. Citation Adeyemo WL, Ladeinde AL, Ogunlewe MO. Clinical Evaluation of Post-extraction Site Wound Healing. J Contemp Dent Pract 2006 July;(7)3:040-049.
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Books on the topic "Post-extraction complications"

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Cascarini, Luke, Clare Schilling, Ben Gurney, and Peter Brennan. In the emergency department. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198767817.003.0004.

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This chapter discusses oral and maxillofacial surgery in the A&E department, including, The paediatric OMFS patient, Overview of maxillofacial trauma, Mandibular fractures, Zygomatic fractures, Orbital floor fractures, Maxillary fractures, Nose, naso-ethmoidal, and frontal bone fractures, Face and scalp soft tissue injuries, Penetrating injuries to the neck, Intra-oral injuries, Dento-alveolar trauma, Dento-alveolar infections, Post-extraction complications, Head and neck soft tissue infections, Salivary gland diseases, and Miscellaneous conditions
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Palomäki, Outi, and Petri Volmanen. Alternative neural blocks for labour analgesia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0018.

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Although neuraxial analgesia is available to the majority of parturients in developed countries, alternative neural blocks for labour analgesia are needed for medical, individual, and institutional reasons. Paracervical and pudendal blocks are usually administered transvaginally by an obstetrician. An injection of 0.25% bupivacaine using a superficial technique into the lateral fornixes gives rapid pain relief and has been found to have no negative effect on either fetal oxygenation, or maternal and neonatal outcomes. Low rates of post-analgesic bradycardia and high rates of spontaneous vaginal delivery have been described in low-risk populations. The analgesic effect of a paracervical block is moderate and is limited to the first stage of labour. A pudendal block, administered transvaginally, can be used for pain relief in the late first stage, the second stage, in cases of vacuum extraction, or for episiotomy repair. In clinical use, 1% lidocaine gives rapid pain relief but the success rate is variable. The complications of pudendal block are rare and localized. The sympathetic and paravertebral blocks are currently mainly of historic interest. However, they may benefit parturients in exceptional conditions if the anaesthesiologist is experienced in the techniques. Lumbar sympathetic block provides fast pain relief during the first stage of labour when a combination of 0.5% bupivacaine with fentanyl and epinephrine is employed. With the currently available data, no conclusion on the analgesic effects of thoracic paravertebral block can be drawn when it is used for labour pain relief. Potential maternal risks limit the use of these methods in modern obstetrics.
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Book chapters on the topic "Post-extraction complications"

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Oram, Osman. "Axial Length Changes." In Complications of Glaucoma Surgery. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780195382365.003.0062.

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The biometric changes of the human eye with lowered intraocular pressure (IOP), like those observed after glaucoma surgery, have been investigated by in vivo studies. Leydolt et al demonstrated IOP-dependent axial eye length changes in human eyes. An axial eye length decrease of 2 μm/mm Hg with short-term reduction of IOP was observed. They suggested that this concomitant shortening of axial length and IOP reduction could be a result of a decrease in scleral length owing to the reduced IOP or an increase in choroidal blood flow compensating the reduced ocular fundus pulsations during the increased IOP phase. In another in vivo study, Read et al showed that axial length underwent significant variation over a 24-hour period in normal human eyes, and a significant association existed between the change in axial length and the change in IOP, as measured by dynamic contour tonometry. The association observed between IOP and axial length was found to be consistent with the hypothesis of passive expansion and contraction of the globe in response to IOP. Studies on trabeculectomy patients, performed with or without cataract extraction, have shown a significant decrease of axial length after surgery, correlated with IOP reduction. Similarly, IOP lowering after tube shunt surgery may produce a decrease in axial length that is dependent on the amount of IOP lowering. Understanding how axial length changes impact clinical decisions, such as lens power choice for cataract surgery, is important for treating patients after glaucoma surgery or patients who have had previous glaucoma surgery. Table 41.1 summarizes reported axial length changes following different types of trabeculectomy procedures. Nemeth and Horoczi noted decreased axial length and increased thickness and volume of the ocular wall 4 days after trabeculectomy. In a retrospective study, Cashwell and Martin found a significant decrease in axial length (mean: 0.423 mm, range: 2.8 to +0.5 mm) after successful initial trabeculectomy in 62 patients using ultrasound biometry. Preoperative factors found to be associated with a greater decrease in axial length were young age, myopia, exposure to an antimetabolite, and a post-trabeculectomy IOP drop greater than 30 mmHg.
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Mitchell, David A., Laura Mitchell, and Lorna McCaul. "Oral surgery." In Oxford Handbook of Clinical Dentistry. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199679850.003.0009.

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Contents. Principles of surgery of the mouth. Asepsis and antisepsis. Forceps, elevators, and other instruments. The extraction of teeth. Complications of extracting teeth. Post-operative bleeding. Suturing. Dento-alveolar surgery: bisphosphonates. Dento-alveolar surgery: removal of roots. Dento-alveolar surgery: removal of unerupted teeth. Dento-alveolar surgery: removal of third molars. Dento-alveolar surgery: coronectomy. Dento-alveolar surgery: third-molar technique. Dento-alveolar surgery: apicectomy. Dento-alveolar surgery: other aids to endodontics. Dento-alveolar surgery: helping the orthodontist. Dento-facial infections. Biopsy. Cryosurgery. Non-tumour soft-tissue lumps in the mouth. Non-tumour hard-tissue lumps. Cysts of the jaws. Benign tumours of the mouth. The maxillary antrum. Minor preprosthetic surgery. Implantology. Lasers. Minimally invasive surgery.
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Rabie, Bassam. "Managing Soft tissue complication in Immediate Post Extraction Implants." In Treatment Planning Steps in Oral Implantology: A Color Atlas. Jaypee Brothers Medical Publishers (P) Ltd., 2018. http://dx.doi.org/10.5005/jp/books/14127_125.

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García G., Maiora J., Tapia A., and De Blas M. "Computer-aided Diagnosis of Abdominal Aortic Aneurysm after Endovascular Repair Using Texture Analysis." In Frontiers in Artificial Intelligence and Applications. IOS Press, 2012. https://doi.org/10.3233/978-1-61499-105-2-716.

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Endovascular repair is a minimal invasive alternative to open surgical therapy. From a long term perspective, complications such as prostheses displacement or leaks inside the aneurysm sac (endoleaks) could appear influencing the evolution of treatment. The objective of this work is to develop a preliminary Computer-aided diagnosis system (CAD) for an automated classification of EVAR progression from computed tomography angiography CTA images. The system is based on the extraction of texture features from thrombus aneurysm samples and a posterior classification. Regions of interest (ROIs) from patients with different post-EVAR evolution were extracted by experienced radiologists. Three conventional texture-analysis methods such as the gray level co-occurrence matrix (GLCM), the gray level run length matrix (GLRLM), and the gray level difference method (GLDM), were applied to each ROI to obtain texture features. Classification of the ROI is carried out by three different strategies. In the first one each feature set is fed to a neural network (NN). The second consists of a single neural network fed with a reduced version of texture features after a feature selection process. The third one comprised an ensembles of classifiers (ECs), formed by three NNs, each using as input one of the feature sets. The final decision is based on the application of a voting scheme across the outputs of the individual NNs. Classification results from the three classification strategies are evaluated using a receiver operating-characteristics (ROC) analysis and area under the roc curve (Az) performance. The multiple classification scheme using the three sets of texture features results in a better performance, as compared to the classification performance of the other alternatives.
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Esteban, Olivia, Javier Mateo, Paula Casas, Javier Lara, and Javier Ascaso. "Cataract Surgery in Post-Vitrectomized Eyes." In Current Cataract Surgical Techniques. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95467.

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Because of the application of vitreoretinal surgical techniques to a broader range of posterior segment diseases and because cataract develops frequently in postvitrectomy eyes, cataract surgeons should be familiar with the challenges of cataract extraction in vitrectomized eyes. Cataract surgery after pars plana vitrectomy significantly improves visual acuity in 85% of cases, limited by retinal comorbidity and surgical complications. However, despite recent advances, this surgery remains a special challenge. The cataract surgeon can prepare for these challenges with awareness of such potential factors as an excessively mobile posterior capsule, silicon oil removal and special considerations concerning intraocular lens selection and power calculation. And consider the postoperative complications as posterior capsule opacification or refractive errors.
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Conference papers on the topic "Post-extraction complications"

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Sun, Wei, James G. Brigman, Cheng Ji, Pratap Nair, Fangyuan Ma, and Jingde Wang. "Data-Driven Soft Sensors for Process Industries: Case Study on a Delayed Coker Unit." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.185205.

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This research addresses the challenges associated with data-driven soft sensors in industrial applications, where successful implementations remain limited. The scarcity of practical applications can be attributed to variable operating conditions and frequent disturbances in real-time processes. Industrial data are often nonlinear, dynamic, and highly unbalanced, complicating efforts to capture the essential characteristics of underlying processes. To tackle these issues, we propose a comprehensive solution for industrial application, that encompasses feature selection, feature extraction, and model updating. Feature selection aims to pinpoint the independent variables that have a substantial impact on key performance indicators, including quality, safety, efficiency, reliability, and sustainability. By doing so, it simplifies the model and boosts its predictive accuracy. The process begins with screening variables based on process knowledge, followed by a thorough analysis of correlation and redundancy to eliminate redundant information, which can burden computational resources and degrade prediction accuracy. We propose a mutual information-based algorithm for feature selection that assesses the relevance and redundancy among process variables through a comprehensive correlation function. This algorithm ranks variables by their importance using a Greedy search method to identify the optimal set of variables. After selecting the optimal variables, feature extraction is carried out to derive internal features from this set and establish a relationship between these latent features and the output variables. Given the intricate nature of industrial processes, we employ deep learning techniques, specifically Long Short-Term Memory (LSTM) networks, which are a type of Recurrent Neural Network (RNN) well-suited for capturing long-term dependencies in sequential data. LSTMs excel at modeling temporal correlations due to their ability to maintain memory states that allow for learning from sequential data over extended periods. To address short-term nonstationary features resulting from process disturbances, we incorporate a differential unit into the latent layer of the LSTM network. Once trained, the model is updated during online applications to incorporate gradual changes in equipment and reaction agents. Quality-related data, although typically available only post-measurement, can be leveraged to fine-tune model parameters, ensuring sustained predictive accuracy over time. To validate our approach, we present a case study on a delayed coker unit, yielding promising long-term predictions for tube metal temperature and showcasing the potential of our methodology for industrial applications.
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Reports on the topic "Post-extraction complications"

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Dioguardi, Mario. Post-Extraction Complications in Patients Undergoing Oral Bisphosphonate Therapy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0035.

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Dignam, Peter, Mariam Elshafey, Aparna Jeganathan, Magdalen Foo, Joon Soo Park, and Manorika Ratnaweera. Prevalence and factors influencing post-operative complications following tooth extraction: Narrative review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.4.0028.

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Hsieh, Patrick, Eric Apaydin, Robert G. Briggs, et al. Diagnosis and Treatment of Tethered Spinal Cord. Agency for Healthcare Research and Quality (AHRQ), 2024. http://dx.doi.org/10.23970/ahrqepccer274.

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Objectives. To summarize the evidence regarding diagnosis, prophylactic treatment, symptomatic treatment, and repeat surgery of tethered spinal cord. Data sources. We searched PubMed®, Embase®, CINAHL, Web of Science, SCOPUS, clinicaltrials.gov, ICTRP, Cochrane Database of Systematic Reviews, PROSPERO, ECRI repository, G-I-N, MagicApp, and ClinicalKey from inception to March 2024; reference-mined reviews; and contacted research authors. Review methods. The review followed a detailed protocol and was supported by a Technical Expert Panel. Systematic review software (DistillerSR) was utilized for all screening and data extraction tasks. Citation screening was facilitated by machine learning; two independent reviewers each screened full text citations for eligibility; one literature reviewer extracted data and a methodologist checked for accuracy. Risk of bias assessments focused on key sources of bias for diagnostic and intervention studies. We conducted strength of evidence (SoE) and applicability assessments for key outcomes. The protocol for the review has been registered in PROSPERO (CRD42023461296). Results. Searches identified 6,285 citations; 2,005 were obtained as full text. In total, 103 studies met inclusion criteria, with an additional 355 case series providing additional information. We found the strongest evidence for accuracy of MRI in diagnosing tethered spinal cord. Specifically, studies indicated this modality has medium to high diagnostic sensitivity and specificity (moderate SoE). A small number of existing studies suggested benefits of prophylactic surgery, but it was also associated with complications such as surgical site infection (low SoE). A larger body of evidence evaluated various treatments for symptomatic patients, with the majority focused on surgical detethering. Studies reported improvement of neurological status after surgical detethering (low SoE), but it was also associated with post-operative complications such as cerebrospinal fluid leakage (moderate SoE). A very small body of evidence exists for revision detethering and spinal column shortening for repeat surgery (low or insufficient SoE for all outcomes). Across diagnosis, prophylactic treatment, symptomatic treatment, and repeat surgery there was insufficient evidence for multiple key outcomes (e.g., over- or undertreatment, clinical impact of diagnostic modalities, ambulation or quality of life outcomes) and thus no evidence statements could be derived. Conclusions. The evidence base for the diagnosis and treatment of tethered spinal cord is limited, with few exceptions (use of MRI or ultrasound for diagnosis, surgical detethering improving neurological status in symptomatic patients, complications associated with open detethering surgery) and would benefit from stronger study designs that include tool evaluations reporting diagnostic performance and treatment studies with concurrent comparator.
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