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Journal articles on the topic 'Post-transcriptional gene regulation'

Author: Grafiati

Published: 4 June 2021

Last updated: 21 February 2023

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1

Tew, Simon R., and Peter D. Clegg. "Post-transcriptional gene regulation in chondrocytes." Biochemical Society Transactions 38, no. 6 (November 24, 2010): 1627–31. http://dx.doi.org/10.1042/bst0381627.

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The control of gene expression in articular chondrocytes is an essential factor in maintaining the homoeostasis of extracellular matrix synthesis and turnover necessary in healthy articular cartilage. Although much is known of how steady-state levels of gene expression and rates of transcription are altered, there has been a poorer understanding of gene control at the post-transcriptional level and its relevance to cartilage health and disease. Now, an emerging picture is developing of the importance of this tier of gene regulation, driven by in vitro studies and mouse genetic models. This lev

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2

Lipshitz, Howard D., Julie M. Claycomb, and Craig A. Smibert. "Post-transcriptional regulation of gene expression." Methods 126 (August 2017): 1–2. http://dx.doi.org/10.1016/j.ymeth.2017.08.007.

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3

Kashanchi, Fatah, and John N. Brady. "Transcriptional and post-transcriptional gene regulation of HTLV-1." Oncogene 24, no. 39 (September 2005): 5938–51. http://dx.doi.org/10.1038/sj.onc.1208973.

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4

Alonso, C. R. "Post-transcriptional gene regulation via RNA control." Briefings in Functional Genomics 12, no. 1 (January 1, 2013): 1–2. http://dx.doi.org/10.1093/bfgp/els060.

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5

Zhao, Boxuan Simen, Ian A. Roundtree, and Chuan He. "Post-transcriptional gene regulation by mRNA modifications." Nature Reviews Molecular Cell Biology 18, no. 1 (November 3, 2016): 31–42. http://dx.doi.org/10.1038/nrm.2016.132.

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6

Swaminathan, Sankar. "Post-transcriptional gene regulation by gamma herpesviruses." Journal of Cellular Biochemistry 95, no. 4 (2005): 698–711. http://dx.doi.org/10.1002/jcb.20465.

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7

Sadelain, Michel. "Transcriptional and post transcriptional gene regulation in stem cell-based gene therapy." Blood Cells, Molecules, and Diseases 40, no. 2 (March 2008): 283. http://dx.doi.org/10.1016/j.bcmd.2007.10.074.

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8

Kuhlemier, Cris. "Transcriptional and post-transcriptional regulation of gene expression in plants." Plant Molecular Biology 19, no. 1 (May 1992): 1–14. http://dx.doi.org/10.1007/bf00015603.

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9

Ray, Swagat, Pól Ó. Catnaigh, and Emma C. Anderson. "Post-transcriptional regulation of gene expression by Unr." Biochemical Society Transactions 43, no. 3 (June 1, 2015): 323–27. http://dx.doi.org/10.1042/bst20140271.

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Unr (upstream of N-ras) is a eukaryotic RNA-binding protein that has a number of roles in the post-transcriptional regulation of gene expression. Originally identified as an activator of internal initiation of picornavirus translation, it has since been shown to act as an activator and inhibitor of cellular translation and as a positive and negative regulator of mRNA stability, regulating cellular processes such as mitosis and apoptosis. The different post-transcriptional functions of Unr depend on the identity of its mRNA and protein partners and can vary with cell type and changing cellular

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10

Sánchez-Jiménez, Flora, and Víctor Sánchez-Margalet. "Role of Sam68 in Post-Transcriptional Gene Regulation." International Journal of Molecular Sciences 14, no. 12 (November 28, 2013): 23402–19. http://dx.doi.org/10.3390/ijms141223402.

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11

Boyne, J. R., та A. Whitehouse. "γ-2 herpes virus post-transcriptional gene regulation". Clinical Microbiology and Infection 12, № 2 (лютий 2006): 110–17. http://dx.doi.org/10.1111/j.1469-0691.2005.01317.x.

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12

Klausner, R., and J. Harford. "cis-trans models for post-transcriptional gene regulation." Science 246, no. 4932 (November 17, 1989): 870–72. http://dx.doi.org/10.1126/science.2683086.

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13

Borden, K., B. Culjkovic, and S. Vukosavic. "eIF4E and post-transcriptional gene regulation in cancer." European Journal of Cancer Supplements 6, no. 9 (July 2008): 2. http://dx.doi.org/10.1016/s1359-6349(08)71182-0.

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14

Glisovic, Tina, Jennifer L. Bachorik, Jeongsik Yong, and Gideon Dreyfuss. "RNA-binding proteins and post-transcriptional gene regulation." FEBS Letters 582, no. 14 (March 13, 2008): 1977–86. http://dx.doi.org/10.1016/j.febslet.2008.03.004.

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15

Fujiwara, Shinsuke, and A. M. Chakrabarty. "Post-transcriptional regulation of the Pseudomonas aeruginosaalgC gene." Gene 146, no. 1 (August 1994): 1–5. http://dx.doi.org/10.1016/0378-1119(94)90826-5.

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16

Roger, T., X. Ding, A. L. Chanson, P. Renner, and T. Calandra. "84 Transcriptional and post-transcriptional regulation of human MIF gene expression." International Journal of Infectious Diseases 10 (2006): S47—S48. http://dx.doi.org/10.1016/s1201-9712(06)80081-0.

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17

Dykes, Iain M., and Costanza Emanueli. "Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA." Genomics, Proteomics & Bioinformatics 15, no. 3 (June 2017): 177–86. http://dx.doi.org/10.1016/j.gpb.2016.12.005.

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18

Fenton, Matthew J. "Review: Transcriptional and post-transcriptional regulation of interleukin 1 gene expression." International Journal of Immunopharmacology 14, no. 3 (April 1992): 401–11. http://dx.doi.org/10.1016/0192-0561(92)90170-p.

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19

Distel, R. J., G. S. Robinson, and B. M. Spiegelman. "Fatty acid regulation of gene expression. Transcriptional and post-transcriptional mechanisms." Journal of Biological Chemistry 267, no. 9 (March 1992): 5937–41. http://dx.doi.org/10.1016/s0021-9258(18)42645-2.

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20

Sankaran, Vijay G. "Post-Transcriptional Defects and Erythroid Pathobiology." Blood 124, no. 21 (December 6, 2014): SCI—35—SCI—35. http://dx.doi.org/10.1182/blood.v124.21.sci-35.sci-35.

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A great body of work has focused on understanding the role that gene regulation at the transcriptional level plays in blood cell production and diseases that disrupt this process. However, until recently there has been limited insight on the role that post-transcriptional gene regulation has in both normal and pathological disorders of human hematopoiesis. Specifically, the regulation of messenger RNA translation can have a significant impact upon gene expression, and how this process affects hematopoiesis has only been explored in limited studies. In this talk, the role of ribosomal protein g

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21

Witzel, Ini-Isabée, Li Fang Koh, and Neil D. Perkins. "Regulation of cyclin D1 gene expression." Biochemical Society Transactions 38, no. 1 (January 19, 2010): 217–22. http://dx.doi.org/10.1042/bst0380217.

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Cyclin D1 is a key regulator of cell proliferation and its expression is subject to both transcriptional and post-transcriptional regulation. In different cellular contexts, different pathways assume a dominant role in regulating its expression, whereas their disregulation can contribute to overexpression of cyclin D1 in tumorigenesis. Here, we discuss the ability of the NF-κB (nuclear factor κB)/IKK [IκB (inhibitor of NF-κB) kinase] pathways to regulate cyclin D1 gene transcription and also consider the newly discovered role of the SNARP (SNIP1/SkIP-associated RNA processing) complex as a co-

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22

Liu, Meilian, and Feng Liu. "Transcriptional and post-translational regulation of adiponectin." Biochemical Journal 425, no. 1 (December 14, 2009): 41–52. http://dx.doi.org/10.1042/bj20091045.

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Adiponectin is an adipose-tissue-derived hormone with anti-diabetic, anti-atherogenic and anti-inflammatory functions. Adiponectin circulates in the bloodstream in trimeric, hexameric and high-molecular-mass species, and different forms of adiponectin have been found to play distinct roles in the regulation of energy homoeostasis. The serum levels of adiponectin are negatively correlated with obesity and insulin resistance, yet the underlying mechanisms remain elusive. In the present review, we summarize recent progress made on the mechanisms regulating adiponectin gene transcription, multimer

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23

van Grinsven, M. Q. J. M., J. J. L. Gielen, J. L. A. Zethof, H. J. J. Nijkamp, and A. J. Kool. "Transcriptional and post-transcriptional regulation of chloroplast gene expression in Petunia hybrida." Theoretical and Applied Genetics 73, no. 1 (November 1986): 94–101. http://dx.doi.org/10.1007/bf00273725.

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24

Anderson, C. J., S. F. Hoare, M. Ashcroft, A. E. Bilsland, and W. N. Keith. "Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms." Oncogene 25, no. 1 (September 19, 2005): 61–69. http://dx.doi.org/10.1038/sj.onc.1209011.

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25

Kula, Anna, and Alessandro Marcello. "Dynamic Post-Transcriptional Regulation of HIV-1 Gene Expression." Biology 1, no. 2 (July 3, 2012): 116–33. http://dx.doi.org/10.3390/biology1020116.

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26

Ellis, Tannis J., and Graham F. Wagner. "Post-transcriptional Regulation of the Stanniocalcin Gene by Calcium." Journal of Biological Chemistry 270, no. 4 (January 27, 1995): 1960–65. http://dx.doi.org/10.1074/jbc.270.4.1960.

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27

Yue, Yanan, Jianzhao Liu, and Chuan He. "RNAN6-methyladenosine methylation in post-transcriptional gene expression regulation." Genes & Development 29, no. 13 (July 1, 2015): 1343–55. http://dx.doi.org/10.1101/gad.262766.115.

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28

Khanin, Raya, and Veronica Vinciotti. "Computational Modeling of Post-Transcriptional Gene Regulation by MicroRNAs." Journal of Computational Biology 15, no. 3 (April 2008): 305–16. http://dx.doi.org/10.1089/cmb.2007.0184.

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29

CLERCH, LINDA BIADASZ. "Post-Transcriptional Regulation of Lung Antioxidant Enzyme Gene Expression." Annals of the New York Academy of Sciences 899, no. 1 (January 25, 2006): 103–11. http://dx.doi.org/10.1111/j.1749-6632.2000.tb06179.x.

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30

McKay, Bruce C. "Post-Transcriptional Regulation of DNA Damage-Responsive Gene Expression." Antioxidants & Redox Signaling 20, no. 4 (February 2014): 640–54. http://dx.doi.org/10.1089/ars.2013.5523.

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31

Peffers, M. J., R. Fentom, S. R. Tew, and P. D. Clegg. "Post transcriptional gene regulation in ageing cartilage and chondrocytes." Osteoarthritis and Cartilage 22 (April 2014): S62—S63. http://dx.doi.org/10.1016/j.joca.2014.02.128.

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32

Neil, Christopher R., and William G. Fairbrother. "Intronic RNA: Ad‘junk’ mediator of post-transcriptional gene regulation." Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862, no. 11-12 (November 2019): 194439. http://dx.doi.org/10.1016/j.bbagrm.2019.194439.

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33

Goldie, Belinda J., and Murray J. Cairns. "Post-Transcriptional Trafficking and Regulation of Neuronal Gene Expression." Molecular Neurobiology 45, no. 1 (December 14, 2011): 99–108. http://dx.doi.org/10.1007/s12035-011-8222-0.

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34

Nishizawa, Mikio. "Post-transcriptional inducible gene regulation by natural antisense RNA." Frontiers in Bioscience 20, no. 1 (2015): 1–36. http://dx.doi.org/10.2741/4297.

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35

Zhao, Boxuan Simen, Ian A. Roundtree, and Chuan He. "Publisher Correction: Post-transcriptional gene regulation by mRNA modifications." Nature Reviews Molecular Cell Biology 19, no. 12 (October 19, 2018): 808. http://dx.doi.org/10.1038/s41580-018-0075-1.

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36

Carpenter, Susan, Emiliano P. Ricci, Blandine C. Mercier, Melissa J. Moore, and Katherine A. Fitzgerald. "Post-transcriptional regulation of gene expression in innate immunity." Nature Reviews Immunology 14, no. 6 (May 23, 2014): 361–76. http://dx.doi.org/10.1038/nri3682.

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37

Corbett, Anita H. "Post-transcriptional regulation of gene expression and human disease." Current Opinion in Cell Biology 52 (June 2018): 96–104. http://dx.doi.org/10.1016/j.ceb.2018.02.011.

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38

Akker, SA, PJ Smith, and SL Chew. "Nuclear post-transcriptional control of gene expression." Journal of Molecular Endocrinology 27, no. 2 (October 1, 2001): 123–31. http://dx.doi.org/10.1677/jme.0.0270123.

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The mammalian nucleus has considerable control over nascent transcripts. The basic mechanisms of post-transcriptional processing are well understood and recently some of the principles underlying the regulation of nuclear processing events have been elucidated. Here we review the recent progress in identification of signalling pathways that modulate the action of key RNA-binding proteins which regulate splicing, and the mechanisms of action of the C-terminal domain of RNA polymerase II that co-ordinate transcription with nuclear mRNA processing events.

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39

Swaminathan, Sanjay, Chantelle L. Hood, Kazuo Suzuki, and Anthony D. Kelleher. "RNA duplexes in transcriptional regulation." BioMolecular Concepts 1, no. 3-4 (October 1, 2010): 285–96. http://dx.doi.org/10.1515/bmc.2010.021.

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AbstractTranscriptional regulation by small RNA molecules, including small interfering RNA and microRNA, has emerged as an important gene expression modulator. The regulatory pathways controlling gene expression, post-transcriptional gene silencing and transcriptional gene silencing (TGS) have been demonstrated in yeast, plants and more recently in human cells. In this review, we discuss the currents models of transcriptional regulation and the main components of the RNA-induced silencing complex and RNA-induced transcriptional silencing complex machinery, as well as confounding off-target eff

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40

Rosa, F. M., and M. Fellous. "Regulation of HLA-DR gene by IFN-gamma. Transcriptional and post-transcriptional control." Journal of Immunology 140, no. 5 (March 1, 1988): 1660–64. http://dx.doi.org/10.4049/jimmunol.140.5.1660.

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Abstract IFN-gamma increases the synthesis and level of mRNA of the HLA class I and II genes, in human cells such as melanomas which normally express both classes of molecules. It also induces the surface expression and mRNA synthesis of HLA-DR genes on cells which normally do not express HLA class II genes such as skin fibroblasts. We have investigated the mechanism by which IFN-gamma increases mRNA levels for class II MHC antigens in human cells. For this purpose, we have studied the effect of IFN-gamma on HLA-DR-alpha transcription rate in two different human cell types: VAL melanoma and JD

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41

Vyas, S., N. Faucon Biguet, and J. Mallet. "Transcriptional and post-transcriptional regulation of tyrosine hydroxylase gene by protein kinase C." EMBO Journal 9, no. 11 (November 1990): 3707–12. http://dx.doi.org/10.1002/j.1460-2075.1990.tb07583.x.

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42

M, Hitit. "Putative Role of Micro - RNA s i n Female Reproductive Tract." Open Access Journal of Veterinary Science & Research 2, no. 2 (2017): 1–5. http://dx.doi.org/10.23880/oajvsr-16000131.

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Female reproductive tract is composed of ovarium, oviduct, cervix and uterus. Development and function of reproductive tract is dispens a ble for maintenance and achievement of reproduction. Reproductive tract responses to cyclic changes and ovarium hormones which provide optimum conditions for gam e t e movement and development. While the potential influence of pitu i tary and gonadal hormones on reproductive function is clearly understood, the molecular mechanism regulating reproductive tract remains elusive. Although, post - transcriptional gene regulation has critical role in cell differ e

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43

Day, DA, and MF Tuite. "Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview." Journal of Endocrinology 157, no. 3 (June 1, 1998): 361–71. http://dx.doi.org/10.1677/joe.0.1570361.

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Expression of a gene can be controlled at many levels, including transcription, mRNA splicing, mRNA stability, translation and post-translational events such as protein stability and modification. The majority of studies to date have focused on transcriptional control mechanisms, but the importance of post-transcriptional mechanisms in regulating gene expression in eukaryotes is becoming increasingly clear. In this short review, selected examples of post-transcriptional gene regulatory mechanisms operating in both lower and higher eukaryotes will be used to highlight the plethora of such mecha

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44

Aguilera, G., S. Volpi, and C. Rabadan-Diehl. "Transcriptional and post-transcriptional mechanisms regulating the rat pituitary vasopressin V1b receptor gene." Journal of Molecular Endocrinology 30, no. 2 (April 1, 2003): 99–108. http://dx.doi.org/10.1677/jme.0.0300099.

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The number of V1b vasopressin receptors (V1bR) in the anterior pituitary plays an important role during adaptation of the hypothalamic-pituitary-adrenal axis to stress in rats. Regulation of V1bR expression involves transcriptional and translational mechanisms. One of the elements mediating transcriptional activation of the rat V1bR gene is a long stretch of GAGA repeats (GAGA box) in the promoter located near the transcription start point capable of binding a protein complex of 127 kDa present in pituitary nuclear extracts. There is a lack of correlation between changes in V1bR mRNA and the n

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45

Laloo, Benoît, Marion Maurel, Sandra Jalvy-Delvaille, Francis Sagliocco, and Christophe F. Grosset. "Analysis of post-transcriptional regulation using the FunREG method." Biochemical Society Transactions 38, no. 6 (November 24, 2010): 1608–14. http://dx.doi.org/10.1042/bst0381608.

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An increasing number of arguments, including altered microRNA expression, support the idea that post-transcriptional deregulation participates in gene disturbances found in diseased tissues. To evaluate this hypothesis, we developed a method which facilitates post-transcriptional investigations in a wide range of human cells and experimental conditions. This method, called FunREG (functional, integrated and quantitative method to measure post-transcriptional regulation), connects lentiviral transduction with a fluorescent reporter system and quantitative PCR. Using FunREG, we efficiently measu

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46

De Gaudenzi, Javier G., Griselda Noé, Vanina A. Campo, Alberto C. Frasch, and Alejandro Cassola. "Gene expression regulation in trypanosomatids." Essays in Biochemistry 51 (October 24, 2011): 31–46. http://dx.doi.org/10.1042/bse0510031.

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Trypanosomatids are protozoan micro-organisms that cause serious health problems in humans and domestic animals. In addition to their medical relevance, these pathogens have novel biological structures and processes. From nuclear DNA transcription to mRNA translation, trypanosomes use unusual mechanisms to control gene expression. For example, transcription by RNAPII (RNA polymerase II) is polycistronic, and only a few transcription initiation sites have been identified so far. The sequences present in the polycistronic units code for proteins having unrelated functions, that is, not involved

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47

Martínez-Andújar, C., R. C. Martin, G. W. Bassel, M. B. Arun Kumar, W. E. Pluskota, and H. Nonogaki. "POST-TRANSCRIPTIONAL GENE REGULATION DURING SEED GERMINATION AND STAND ESTABLISHMENT." Acta Horticulturae, no. 898 (June 2011): 53–59. http://dx.doi.org/10.17660/actahortic.2011.898.5.

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48

Ghanekar, Yashoda, and Subhashini Sadasivam. "RNA Editing–Associated Post-Transcriptional Gene Regulation in Rheumatoid Arthritis." Bioinformatics and Biology Insights 16 (January 2022): 117793222210887. http://dx.doi.org/10.1177/11779322221088725.

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Background: Rheumatoid arthritis (RA) is an autoimmune disease characterised by systemic inflammation of joints. The observed complexity of RA pathogenesis and studies that have been carried out so far indicate that RA pathogenesis is regulated at multiple levels. Given the role of RNA editing in autoimmune disease, we hypothesised that RNA editing could contribute to RA pathogenesis by regulating gene expression through post-transcriptional mechanisms. Methods: We identified RNA editing events in synovial tissues from early and established RA compared with normal subjects from an available tr

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49

McFadden, Michael J., Alexa B. R. McIntyre, Haralambos Mourelatos, Nathan S. Abell, Nandan S. Gokhale, Hélène Ipas, Blerta Xhemalçe, Christopher E. Mason, and Stacy M. Horner. "Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine." Cell Reports 34, no. 9 (March 2021): 108798. http://dx.doi.org/10.1016/j.celrep.2021.108798.

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50

Tomasoni, Susanna, and Ariela Benigni. "Post-Transcriptional Gene Regulation Makes Things Clearer in Renal Fibrosis." Journal of the American Society of Nephrology 24, no. 7 (May 30, 2013): 1026–28. http://dx.doi.org/10.1681/asn.2013040411.

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