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Journal articles on the topic 'Postcompression'

Author: Grafiati
Published: 30 November 2024
Last updated: 31 July 2025

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1

Srinivasan, S., F. Kallel, R. Souchon, and J. Ophir. "Analysis of an Adaptive Strain Estimation Technique in Elastography." Ultrasonic Imaging 24, no. 2 (2002): 109–18. http://dx.doi.org/10.1177/016173460202400204.

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Elastography is based on the estimation of strain due to tissue compression or expansion. Conventional elastography involves computing strain as the gradient of the displacement (time-delay) estimates between gated pre- and postcompression signals. Uniform temporal stretching of the postcompression signals has been used to reduce the echo-signal decorrelation noise. However, a uniform stretch of the entire postcompression signal is not optimal in the presence of strain contrast in the tissue and could result in loss of contrast in the elastogram. This has prompted the use of local adaptive str
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2

Yuryk, Yaroslav I. "Morphological features of heart remodeling in the postcompression period of crush syndrome." BULLETIN OF MEDICAL AND BIOLOGICAL RESEARCH 4, no. 1 (2022): 114–17. http://dx.doi.org/10.11603/bmbr.2706-6290.2022.1.12979.

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Summary. In the postcompression period of crush syndrome regenerative processes develop restorative processes in target organs, in particular in the heart. However, the dynamics of myocardial regenerative changes in the postcompression period in crush syndrome is insufficiently covered in professional literature and requires comprehension study and clarified. The aim of the study – to find out features of regenerative changes in heart of laboratory rats in the dynamics in the postcompression period of crush syndrome. Materials and Methods. Light-optical and polarization were performed examinat
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Planck, S. M., F. W. Klaiber, and K. F. Dunker. "Postcompression and Superimposed Trusses for Bridge Rehabilitation." Journal of Structural Engineering 119, no. 3 (1993): 978–91. http://dx.doi.org/10.1061/(asce)0733-9445(1993)119:3(978).

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4

Alonso, Benjamín, Rocío Borrego-Varillas, Íñigo J. Sola, et al. "Enhancement of filamentation postcompression by astigmatic focusing." Optics Letters 36, no. 19 (2011): 3867. http://dx.doi.org/10.1364/ol.36.003867.

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Krynytska, Inna, Ivan Smachylo, Sergii Grabchak, and Mariya Marushchak. "Comparative features of bioelements content in blood, liver and bone tissues in a rat model of crush-syndrome." Bangladesh Journal of Medical Science 23, no. 3 (2024): 714–21. http://dx.doi.org/10.3329/bjms.v23i3.75090.

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Objective: Crush syndrome (CS) remains a life-threatening condition. This research aims to investigate the changes of the macro- and microelement content in blood, liver and bone tissue in a rat model of CS. Methods Studies were conducted on 40 nonlinear mature white male rats. The left hind limb of the rat was subjected to the mechanical pressure for 4 hours. The compressed area was 4 cm with a compressive 2 2 force of 4.25 kg/cm . Determination of total calcium, magnesium and inorganic phosphate contents in blood serum was performed on a semi-automatic biochemical analyser Humalyzer 2000 (Hu
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Balla, Prannay, Ammar Bin Wahid, Ivan Sytcevich, et al. "Postcompression of picosecond pulses into the few-cycle regime." Optics Letters 45, no. 9 (2020): 2572. http://dx.doi.org/10.1364/ol.388665.

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7

Thalluri, Chandrashekar, Ruhul Amin, Jithendar Reddy Mandhadi, et al. "Central Composite Designed Fast Dissolving Tablets for Improved Solubility of the Loaded Drug Ondansetron Hydrochloride." BioMed Research International 2022 (August 21, 2022): 1–13. http://dx.doi.org/10.1155/2022/2467574.

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Ondansetron tablets that are directly compressed using crospovidone and croscarmellose as a synthetic super disintegrant are the subject of this investigation. A central composite, response surface, randomly quadratic, nonblock (version 13.0.9.0) 32 factorial design is used to optimize the formulation (two-factor three-level). To make things even more complicated, nine different formulation batches (designated as F1–F9) were created. There were three levels of crospovidone and croscarmellose (+1, 0, -1). In addition to that, pre- and postcompressional parameters were evaluated, and all evaluat
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Kaur, Lovleen, Rajni Bala, Neha Kanojia, Manju Nagpal, and Gitika Arora Dhingra. "Formulation Development and Optimization of Fast Dissolving Tablets of Aceclofenac Using Natural Superdisintegrant." ISRN Pharmaceutics 2014 (May 8, 2014): 1–10. http://dx.doi.org/10.1155/2014/242504.

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The current research work involves preparation of fast dissolving tablets of Aceclofenac by direct compression method using different concentrations of Lepidium sativum mucilage as natural superdisintegrant. A two-factor three-level (32) factorial design is being used to optimize the formulation. Nine formulation batches (D1–D9) were prepared accordingly. Two factors as independent variables (X1-amount of β-cyclodextrin and X2-amount of Lepidium sativum mucilage) were taken with three levels (+1,0,-1). The levels of two factors were selected on the basis of preliminary experiments conducted an
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9

Swart, Gary, Daniel DeBehnke, and Jeff Glaspy. "HEMODYNAMIC EFFECTS OF POSTCOMPRESSION CHEST WALL REMODELING IN MECHANICAL CARDIOPULMONARY RESUSCITATION." Critical Care Medicine 23, Supplement (1995): A255. http://dx.doi.org/10.1097/00003246-199501001-00451.

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10

Yuryk, Ya I., O. E. Kuziv, and I. I. Yuryk. "Submicroscopic changes of secretory cardiomyocytes in the early postcompression period of crush syndrome." Morphologia 17, no. 3 (2023): 140–46. https://doi.org/10.26641/1997-9665.2023.3.140-146.

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Background. Crush syndrome is manifested by the activation of the pituitary-hypothalamic-adrenal system, what is confirmed by a significant increase in the blood levels of catecholamines, cortisol and corticosterone. Its antagonist is the atrial natriuretic peptide, which is synthesized by the myoendocrine cells of the heart, but the question of its participation in the implementation of the adaptation syndrome under the conditions of the postcompression period of crush syndrome remains unresolved. Objective: to establish submicroscopic changes atrial myoendocrynocytes in the early postcompres
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11

Yaacob, Yusizwan M., Yi Zhang, and Damon M. Chandler. "On the Perceptual Factors Underlying the Quality of PostCompression Enhancement of Textures." Electronic Imaging 2017, no. 14 (2017): 97–103. http://dx.doi.org/10.2352/issn.2470-1173.2017.14.

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12

Yaacob, Yusizwan M., Yi Zhang, and Damon M. Chandler. "On the Perceptual Factors Underlying the Quality of PostCompression Enhancement of Textures." Electronic Imaging 2017, no. 14 (2017): 97–103. http://dx.doi.org/10.2352/issn.2470-1173.2017.14.hvei-123.

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13

Hsin, Hsi-Chin, Tze-Yun Sung, and Yaw-Shih Shieh. "An Adaptive Coding Pass Scanning Algorithm for Optimal Rate Control in Biomedical Images." Computational and Mathematical Methods in Medicine 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/935914.

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High-efficiency, high-quality biomedical image compression is desirable especially for the telemedicine applications. This paper presents an adaptive coding pass scanning (ACPS) algorithm for optimal rate control. It can identify the significant portions of an image and discard insignificant ones as early as possible. As a result, waste of computational power and memory space can be avoided. We replace the benchmark algorithm known as postcompression rate distortion (PCRD) by ACPS. Experimental results show that ACPS is preferable to PCRD in terms of the rate distortion curve and computation t
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14

Abman, S. H., and F. J. Accurso. "Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation." American Journal of Physiology-Heart and Circulatory Physiology 257, no. 2 (1989): H626—H634. http://dx.doi.org/10.1152/ajpheart.1989.257.2.h626.

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To determine the acute effects of increased pulmonary artery pressure and flow on the fetal pulmonary circulation, we studied the response of pulmonary blood flow and vascular reactivity to partial compression of the ductus arteriosus in 22 chronically prepared late-gestation fetal lambs. An inflatable occluder was placed loosely around the ductus arteriosus for compression. Partial compression of the ductus rapidly increased mean pulmonary artery pressure from 45 +/- 1 to 60 +/- 1 mmHg (mean +/- SE) and left pulmonary artery blood flow from 65 +/- 6 to 151 +/- 11 ml/min at 30 min (P less than
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15

Johnson, Blair D., Kieren J. Mather, Sean C. Newcomer, Timothy D. Mickleborough, and Janet P. Wallace. "Vitamin C prevents the acute decline of flow-mediated dilation after altered shear rate patterns." Applied Physiology, Nutrition, and Metabolism 38, no. 3 (2013): 268–74. http://dx.doi.org/10.1139/apnm-2012-0169.

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Oscillatory and retrograde shear rate (SR) impairs endothelial function, potentially through shear-induced oxidative stress. We tested the hypothesis that acute vitamin C supplementation would prevent the attenuation of brachial artery flow-mediated dilation (FMD) after a period of augmented oscillatory and retrograde SR. Twelve healthy men (aged 26 ± 3 years) participated in two 30-min study visits in which one arm was subjected to increased oscillatory and retrograde SR, using 60 mm Hg of forearm cuff compression, and the contralateral arm served as the control. Subjects ingested capsules co
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Korni, Rama D., Kamala KPV, and V. Sahiti. "Fast Dissolving Tablets of Promethazine Theoclate: Optimization by Box Behnken Design." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 126–31. http://dx.doi.org/10.25258/ijddt.14.1.18.

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HThe current work was planned to optimize promethazine theoclate fast-dissolving tablets using Box Behnken design. The effect of three independent factors, the concentration of camphor (sublimating agent), sodium starch glycolate (superdisintegrant) and β-cyclodextrin (solubility enhancer) on two responses, disintegration time and percent drug release was studied. A total of 27 formulations were prepared and tested for various precompression and postcompression parameters. The correlation between factors and responses was established by plotting contour plots. The independent variables, the co
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17

Jiang, Zhaoneng, Ru-shan Chen, Zhenhong Fan, and Maomao Zhu. "Novel postcompression technique in the matrix decomposition algorithm for the analysis of electromagnetic problems." Radio Science 47, no. 2 (2012): n/a. http://dx.doi.org/10.1029/2011rs004921.

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18

Yuryk, Ya I., and I. I. Yuryk. "MORPHOLOGICAL FEATURES OF ADRENAL GLAND REMODELING IN THE EARLY POSTCOMPRESSION PERIOD OF CRUSH SYNDROME." Bulletin of Problems Biology and Medicine 1, no. 3 (2024): 325. http://dx.doi.org/10.29254/2077-4214-2024-3-174-325-332.

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19

M, Jyoshna, Santhi Elveena Alagala, Charishma Manyam, et al. "Formulation and Evaluation of Commiphora wightii Herbal Pills Treatment of Anti-Obesity." International Journal of Clinical Pharmacokinetics and Medical Sciences 4, no. 2 (2024): 21–28. http://dx.doi.org/10.26452/ijcpms.v4i2.614.

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An excessive quantity of bodily fat characterizes a complex disorder called obesity. It raises the risk of developing other illnesses and medical conditions like diabetes, high blood pressure, and heart conditions. When our BMI is 30kg/m2 or greater, obesity is considered to exist. Today, more ailments are treated with traditional herbal medicines than allopathic ones. Compared to herbal medications, allopathic drugs have higher side effects. The current work aims to create and assess the herbal tablet prepared using an ethanolic extract of Commiphora wightii leaves. Wet granulation was used t
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20

Hort, Ondřej, Antoine Dubrouil, Amélie Cabasse, et al. "Postcompression of high-energy terawatt-level femtosecond pulses and application to high-order harmonic generation." Journal of the Optical Society of America B 32, no. 6 (2015): 1055. http://dx.doi.org/10.1364/josab.32.001055.

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21

Yuryk, Ya I. "PECULIARITIES OF ANTIOXIDANT PROTECTION IN HEART AND BLOOD TISSUE RATS IN THE POSTCOMPRESSION PERIOD OF CRUSH SYNDROME." Bulletin of Problems Biology and Medicine 4, no. 1 (2021): 214. http://dx.doi.org/10.29254/2077-4214-2021-4-162-214-217.

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22

Abhijit Sanjay More, Abhijit Sanjay More, and Jayshree Sambhaji Bhadane. "Formulation and Evaluation of Atenolol Tablets Incorporating Tamarind Kernel Powder as a Novel Natural Disintegrant." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 398–405. https://doi.org/10.35629/4494-1002398405.

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: The present study focuses on the formulation and evaluation of Atenolol tablet formulation using Tamarind Kernel Powder (TKP) as a novel natural disintegarant. Atenolol, a βblocker drug used in hypertension and cardiovascular diseases, requires rapid disintegration for effective therapeutic action. Natural disintegrants like TKP offer advantages such as biocompatibility, cost-effectiveness, and sustainability compared to synthetic alternatives.Atenolol tablet formulation were developed using varying levels of tamarind kernel powder (TKP) and subjected to a comprehensive evaluation of their p
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23

Bergenheim, A. Tommy, and Bengt Linderoth. "DIPLOPIA AFTER BALLOON COMPRESSION OF RETROGASSERIAN GANGLION ROOTLETS FOR TRIGEMINAL NEURALGIA." Neurosurgery 62, no. 2 (2008): E533—E534. http://dx.doi.org/10.1227/01.neu.0000316025.58915.10.

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Abstract OBJECTIVE Balloon compression of the rootlets behind the trigeminal ganglion for the treatment of trigeminal neuralgia has become an increasingly popular method among neurosurgeons. However, the method has recognized complications, including double vision. Although occurring infrequently, diplopia may cause the patient significant disability. To minimize the risk for this complication, we analyzed our patients with respect to the surgical technique. METHODS We reviewed our joint consecutive series of 193 patients with trigeminal neuralgia treated with balloon compression. The medical
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P. Samba Siva Rao, P. Samba Siva Rao, Dr G. Nagaraju Dr.G. Nagaraju, L. Sanjeev L. Sanjeev, MD Sana MD. Sana, T. Shivani T. Shivani, and V. Sahithya V. Sahithya. "Review on Formulation and Evaluation of Immediate Release tablets of Bedaquiline." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 211–19. https://doi.org/10.35629/4494-1002211219.

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Bedaquiline, an anti-tubercular agent used in the treatment of multidrug-resistant tuberculosis (MDR-TB). Due to its low aqueous solubility and poor bioavailability, formulation development focused on enhancing the dissolution rate of bedaquiline to achieve rapid therapeutic action. Tablets were prepared using wet granulation method, employing various solubility-enhancing excipients such as surfactants and disintegrants. The prepared formulation was evaluated for precompression parameters, including bulk density, tapped density, and flow properties, as well as postcompression parameters such a
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25

Auguste, Thierry, Oliver Gobert, Coralie Fourcade Dutin, et al. "Application of optical-field-ionization-induced spectral broadening in helium gas to the postcompression of high-energy femtosecond laser pulses." Journal of the Optical Society of America B 29, no. 6 (2012): 1277. http://dx.doi.org/10.1364/josab.29.001277.

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26

Desai, Raghavendra Reddy, Thomas A. Krouskop, and Raffaella Righetti. "Elastography Using Harmonic Ultrasonic Imaging: A Feasibility Study." Ultrasonic Imaging 32, no. 2 (2010): 103–17. http://dx.doi.org/10.1177/016173461003200204.

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Tissue Harmonic Imaging (THI) is a relatively new modality that has had a significant impact in the ultrasound field. In the recent past, imaging the mechanical properties of tissues using elastography has also gained great interest. In this paper, we investigate the feasibility of combining these two state-of-the-art ultrasound-imaging modalities. The performance of elastograms obtained using harmonic ultrasonic signals is studied with simulations and compared to the performance of conventional elastograms using standard statistical methods. Experiments are used as a proof of the technical fe
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Céspedes, Ignacio, and Jonathan Ophir. "Reduction of Image Noise in Elastography." Ultrasonic Imaging 15, no. 2 (1993): 89–102. http://dx.doi.org/10.1177/016173469301500202.

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Elastography is a method for imaging the elastic properties of compliant tissues which produces gray scale elasticity images called elastograms. The elastograms of phantoms with homogeneous elastic properties exhibit a noisy appearance. We demonstrate that this noisy appearance of the elastograms is due to the nonstationary relationship between the pre- and postcompression signals that results in an artifactual modulation of the strain estimates by the amplitude variations of the envelope of the rf signal. We have identified two methods to reduce the strain modulation artifact. The first metho
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Chen, Xiao, and Xiaoqing Xu. "A Fast and Efficient Adaptive Threshold Rate Control Scheme for Remote Sensing Images." Scientific World Journal 2012 (2012): 1–6. http://dx.doi.org/10.1100/2012/691413.

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The JPEG2000 image compression standard is ideal for processing remote sensing images. However, its algorithm is complex and it requires large amounts of memory, making it difficult to adapt to the limited transmission and storage resources necessary for remote sensing images. In the present study, an improved rate control algorithm for remote sensing images is proposed. The required coded blocks are sorted downward according to their numbers of bit planes prior to entropy coding. An adaptive threshold computed from the combination of the minimum number of bit planes, along with the minimum ra
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29

Seidel, Marcus, Prannay Balla, Chen Li, et al. "Factor 30 Pulse Compression by Hybrid Multipass Multiplate Spectral Broadening." Ultrafast Science 2022 (April 1, 2022): 1–10. http://dx.doi.org/10.34133/2022/9754919.

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As ultrafast laser technology advances towards ever higher peak and average powers, generating sub-50 fs pulses from laser architectures that exhibit best power-scaling capabilities remains a major challenge. Here, we present a very compact and highly robust method to compress 1.24 ps pulses to 39 fs by means of only a single spectral broadening stage which neither requires vacuum parts nor custom-made optics. Our approach is based on the hybridization of the multiplate continuum and the multipass cell spectral broadening techniques. Their combination leads to significantly higher spectral bro
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Sravya, Maddukuri, Rajamanickam Deveswaran, Srinivasan Bharath, Basappa Veerbadraiah Basavaraj та Varadharajan Madhavan. "Development of Orodispersible Tablets of Candesartan Cilexetil-β-cyclodextrin Complex". Journal of Pharmaceutics 2013 (24 вересня 2013): 1–13. http://dx.doi.org/10.1155/2013/583536.

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The aim of this study was to investigate the use of inclusion complexation technique employing β-cyclodextrin in improving the dissolution profile of candesartan cilexetil, a BCS class-II drug, and to formulate the inclusion complex into orodispersible tablets. The inclusion complexes were formed by physical mixing, kneading, coevaporation, and lyophilisation methods. Inclusion complexes were characterized by FTIR, DSC, XRD, NMR, and mass spectral studies. Inclusion complexes prepared using kneading, and lyophilisation techniques in the molar ratio 1 : 5 with β-cyclodextrin were used for formu
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31

Srinivasan, S., J. Ophir, and S. K. Alam. "Elastographic Imaging Using Staggered Strain Estimates." Ultrasonic Imaging 24, no. 4 (2002): 229–45. http://dx.doi.org/10.1177/016173460202400403.

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Conventional techniques in elastography estimate strain as the gradient of the displacement estimates obtained through crosscorrelation of pre- and postcompression rf A-lines. In these techniques, the displacements are estimated over overlapping windows and the strains are estimated as the gradient of the displacement estimates over adjacent windows. The large amount of noise at high window overlaps may result in poor quality elastograms, thus restricting the applicability of conventional strain estimation techniques to low window overlaps, which, in turn, results in a small number of pixels i
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Mrs. Pritha Singha Roy, Mrs Pritha Singha Roy, Mr Ankush Biswas Mr. Ankush Biswas, Smriti Pratihar Smriti Pratihar, and Arup Kumar Ghosh Arup Kumar Ghosh. "Effect of Different Binders on Tablet Hardness and Disintegration." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1612–20. https://doi.org/10.35629/4494-100216121620.

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Binders are essential excipients in tablet formulations that influence the mechanical integrity and performance of the dosage form. The present study aimed to evaluate the effects of different binders—namely starch, polyvinylpyrrolidone (PVP K30), gelatin, acacia, and hydroxypropyl methylcellulose (HPMC)—on tablet hardness and disintegration time using a model drug (paracetamol). Five formulations were prepared via wet granulation, maintaining binder concentration at 5% w/w. Standard pre-compression and postcompression parameters were assessed, including flow properties, hardness, friability,
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33

Swamy, N. G. N., P. Shilpa, and Z. Abbas. "FORMULATION AND CHARACTERIZATION OF MEDICATED CHEWING GUMS OF DEXTROMETHORPHAN HYDROBROMIDE." INDIAN DRUGS 49, no. 12 (2012): 29–35. http://dx.doi.org/10.53879/id.49.12.p0029.

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Chewing gums are mobile drug delivery systems, with a potential for administering drugs either for local action or for systemic absorption via buccal route. Dextromethorphan hydrobromide chewing gum formulations were made employing Pharmagum M as the base with an aim to overcome the firstpass effect, reducing the risk of overdosing, ease of administration and for achieving faster systemic absorption. Dextromethorphan hydrobromide was further transformed into spray dried form and incorporated into Pharmagum M base with the object of solubility enhancement and masking the bitter taste of the dru
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Yasmin Begum, M., Ali Alqahtani, Mohammed Ghazwani, et al. "Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100." International Journal of Polymer Science 2021 (March 26, 2021): 1–10. http://dx.doi.org/10.1155/2021/8890503.

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The purpose of the research was to optimize the preparation of duloxetine hydrochloride (duloxetine HCl) delayed release tablets. Duloxetine HCl produces a toxic substance called alpha-naphthol when duloxetine HCl is in contact with gastric fluid. Thus, duloxetine HCl when given orally needed a protective enteric coating that disable the delivery of duloxetine HCl in gastric fluid while enabling the drug delivery only in small intestine. Four different core tablets were prepared by direct compression technique, and the one which displayed quick disintegration and dissolution was chosen for ent
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Soujanya, Anand Kumar Y, and Yashashwini B. "Design, optimization and in vitro characterization of valsartan loaded floating tablets." GSC Biological and Pharmaceutical Sciences 29, no. 3 (2024): 373–85. https://doi.org/10.30574/gscbps.2024.29.3.0433.

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The present work was aim to design and optimize floating drug delivery systems of Valsartan using HPMC K15M, HPMC K100M, Guar gum as polymer and sodium bicarbonate as a gas generating agent. The tablets were prepared by direct compression method. Response surface methodology (RSM) was adapted using Box Behnken Design (BBD) using amount of HPMC K15M (X1), HPMC K100M (X2) and Guar gum (X3) were selected as independent variables, buoyancy time (Y1) and t50 (Y2) selected as dependent variables. All the designed 15 trial batches of formulations were evaluated for precompression, postcompression, dr
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Righetti, Raffaella, Jonathan Ophir, Brian S. Garra, Rajah M. Chandrasekhar, and Thomas A. Krouskop. "A New Method for Generating Poroelastograms in Noisy Environments." Ultrasonic Imaging 27, no. 4 (2005): 201–20. http://dx.doi.org/10.1177/016173460502700401.

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Poroelastography has been recently introduced as a new elastographic technique that may be used to describe the spatial and temporal behavior of poroelastic materials. The experimental methodology proposed thus far for phantoms and tissues in vitro requires the acquisition of a precompression rf frame, the application of a unit step strain compression to the sample and the acquisition of subsequent post-compression frames from the material. Elastograms and poroelastograms are generated by cross-correlating the sequentially-acquired postcompression frames with the reference precompression frame
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Soujanya, Kumar Y. Anand, and B. Yashashwini. "Design, optimization and in vitro characterization of valsartan loaded floating tablets." GSC Biological and Pharmaceutical Sciences 29, no. 3 (2024): 373–85. https://doi.org/10.5281/zenodo.14915723.

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The present work was aim to design and optimize floating drug delivery systems of Valsartan using HPMC K15M, HPMC K100M, Guar gum as polymer and sodium bicarbonate as a gas generating agent. The tablets were prepared by direct compression method. Response surface methodology (RSM) was adapted using Box Behnken Design (BBD) using amount of HPMC K15M (X1), HPMC K100M (X2) and Guar gum (X3) were selected as independent variables, buoyancy time (Y1) and t50 (Y2) selected as dependent variables. All the designed 15 trial batches of formulations were evaluated for precompression, postcompression, dr
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Dhakal, Bhawana, Jaybir Kumar Thakur, Reema Kumari Mahato, et al. "Formulation of Ebastine Fast-Disintegrating Tablet Using Coprocessed Superdisintegrants and Evaluation of Quality Control Parameters." Scientific World Journal 2022 (May 19, 2022): 1–13. http://dx.doi.org/10.1155/2022/9618344.

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Ebastine is a long-acting, nonsedating, second-generation antihistaminic drug that prevents histamine action, mainly in immediate hypersensitivity. This project was aimed to formulate and characterize orodispersible tablets of ebastine, utilizing different proportions of three disintegrants, namely crospovidone, sodium starch glycolate, and coprocessed superdisintegrant. Initially, fifteen trial batches of ebastine orodispersible tablets were outlined using the central composite design of Minitab software. The tablets were formulated by the direct compression method. The compressed tablets wer
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Bayomy, ElSayed Mahmoud, Ahmed Taha Atallah, Mohamed Ebrahim Al-Ashhab, and Shareef Abd Elmoneim Aeltraigy. "Evaluation of the Results of Reconstruction of Medial Patellofemoral Ligament in the Treatment of Recurrent Patellar Instability Using Hamstring Autograft by Dual Patella Docking Technique." Journal of Arthroscopy and Joint Surgery 11, no. 2 (2024): 69–75. http://dx.doi.org/10.4103/jajs.jajs_62_23.

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Abstract Background: Recurrent patellar instability can significantly affect a patient’s life quality. This study evaluated the results of medial patellofemoral ligament (MPFL) reconstruction in the recurrent patellar instability treatment using hamstring autograft by dual patellar docking technique. Materials and Methods: This prospective study was performed on 20 recurrent patellar instability patients. Magnetic resonance imaging and computed tomography scans were performed to confirm MPFL tear and assess the tibial tubercle-trochlear groove distance. Various clinical and radiographic evalua
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Uddin, Ajam, Shimul Halder, Nandita Deb, et al. "Impact of Methods of Preparation on Mechanical Properties, Dissolution Behavior, and Tableting Characteristics of Ibuprofen-Loaded Amorphous Solid Dispersions." Advances in Pharmacological and Pharmaceutical Sciences 2024 (May 28, 2024): 1–15. http://dx.doi.org/10.1155/2024/2303942.

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This study aims to improve the biopharmaceutical, mechanical, and tableting properties of a poorly soluble drug, ibuprofen (IBP), by preparing amorphous solid dispersion (ASD) followed by a sustained-release tablet formulation. A suitable polymer to develop an ASD system was chosen by utilizing the apparent solubility of IBP in various polymer solutions. ASDs containing various ratios of IBP and selected polymer were prepared by the melt fusion (MF) method. ASD containing optimized drug-polymer ratio prepared by freeze-drying (FD) method was characterized and compared physicochemically. The so
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Smielewski, Piotr, Marek Czosnyka, Peter Kirkpatrick, and John D. Pickard. "Evaluation of the transient hyperemic response test in head-injured patients." Journal of Neurosurgery 86, no. 5 (1997): 773–78. http://dx.doi.org/10.3171/jns.1997.86.5.0773.

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✓ The transient hyperemic response test has been shown to provide an index of cerebral autoregulation in healthy individuals and in patients who have suffered a subarachnoid hemorrhage. In this study, the test was applied to patients who had received a severe head injury, and the value of the test was assessed by comparing its result with the individual's clinical condition (Glasgow Coma Scale [GCS] score), cerebral perfusion pressure (CPP), transcranial Doppler wave form—derived index for cerebral autoregulation (relationship between the CPP and the middle cerebral artery flow velocity), and
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Aleti, Rajeswari, Monika Nijhawan, Sailaja Gunnam, et al. "Investigation of Groundnut Shell Powder as Potential Super Disintegrant in Chronotherapeutic Delivery of Sacubitril–valsartan." Asian Journal of Pharmaceutical Research and Health Care 16, no. 3 (2024): 316–21. http://dx.doi.org/10.4103/ajprhc.ajprhc_71_24.

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ABSTRACT Context: Chronotherapeutic delivery of antihypertensives plays a potential role in the treatment by providing a therapeutic amount of drug at the target site in the body. Sacubitril–valsartan (SV), an angiotensin receptor neprilysin inhibitor, has been indicated for the treatment of hypertension. The study explores the formulation and evaluation of compression-coated tablets (CCTs) of SV using a natural super disintegrant in the core tablet for chronotherapeutic drug delivery. Aim and Objective: The main objective of the current investigation is to study the applicability of groundnut
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Chowdary, Y. Ankamma, Ramakrishna Raparla, and Muramshetty Madhuri. "Formulation and Evaluation of Multilayered Tablets of Pioglitazone Hydrochloride and Metformin Hydrochloride." Journal of Pharmaceutics 2014 (May 12, 2014): 1–14. http://dx.doi.org/10.1155/2014/848243.

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In the treatment of type 2 diabetes mellitus a continuous therapy is required which is a more complex one. As in these patients there may be a defect in both insulin secretion and insulin action exists. Hence, the treatment depends on the pathophysiology and the disease state. In the present study, multilayered tablets of pioglitazone hydrochloride 15 mg and metformin hydrochloride 500 mg were prepared in an attempt for combination therapy for the treatment of type 2 diabetes mellitus. Pioglitazone HCl was formulated as immediate release layer to show immediate action by direct compression met
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Thulluru, Ashok, Veeravalli Kumar Sai, Pavan Kumar M, and Roshitha B. "EFFECT OF EFFERVESCENCE IN COMBINATION WITH SUPERDISINTEGRANTS IN THE FORMULATION OF PROPRANOLOL HCL ORAL DISINTEGRATING TABLETS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 3 (2017): 227. http://dx.doi.org/10.22159/ajpcr.2017.v10i3.16096.

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ABSTRACTObjective: The current research work is intended to formulate propranolol HCl (PLH) as orally disintegrating tablet (ODT). It is also intending to checkthe superiority in a combination of superdisintegrants and effervescent mixture than the use of superdisintegrants alone by a direct compressiontechnique. To fasten the onset of action and thereby enhancing the bioavailability of PLH in comparison to its conventional tablets.Methods: Standard calibration curve of PLH was obtained in pH 6.8 phosphate buffer by spectrophotometric method, drug-excipient compatibilitystudies were carried by
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Ittadwar, Parul A., and Prashant k. Puranik. "Formulation and Evaluation of Gastro-retentive Drug Delivery System of Novel Famotidine Phospholipid Complex." International Journal of Pharmaceutical Sciences and Drug Research 15, no. 03 (2023): 250–59. http://dx.doi.org/10.25004/ijpsdr.2023.150304.

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Famotidine is an H2 receptor antagonist belonging to the BCS Class II, characterized by low solubility and limited oral bioavailability. The current study encompasses the formulation of novel famotidine phospholipid complex (FHC) with the aid of design of experiments (Central Composite Design) using solvent evaporation technique to overcome the disadvantages of Famotidine. To further enhance the physicochemical properties of FHC, it was incorporated into gastro-retentive floating tablets (GRDDS) using direct compression technique with sodium bicarbonate as a gas generating agent and its proper
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LoPachin, Richard M., Christopher L. Gaughan, Ellen J. Lehning, Yoshiro Kaneko, Thomas M. Kelly, and Andrew Blight. "Experimental Spinal Cord Injury: Spatiotemporal Characterization of Elemental Concentrations and Water Contents in Axons and Neuroglia." Journal of Neurophysiology 82, no. 5 (1999): 2143–53. http://dx.doi.org/10.1152/jn.1999.82.5.2143.

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To examine the role of axonal ion deregulation in acute spinal cord injury (SCI), white matter strips from guinea pig spinal cord were incubated in vitro and were subjected to graded focal compression injury. At several postinjury times, spinal segments were removed from incubation and rapidly frozen. X-ray microanalysis was used to measure percent water and dry weight elemental concentrations (mmol/kg) of Na, P, Cl, K, Ca, and Mg in selected morphological compartments of myelinated axons and neuroglia from spinal cord cryosections. As an index of axon function, compound action potentials (CAP
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Schwartz, T. M., and R. K. Schwartz. "Paleogene postcompressional intermontane basin evolution along the frontal Cordilleran fold-and-thrust belt of southwestern Montana." Geological Society of America Bulletin 125, no. 5-6 (2013): 961–84. http://dx.doi.org/10.1130/b30766.1.

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Al Hagbani, Turki, and Sami Nazzal. "Development of postcompressional textural tests to evaluate the mechanical properties of medicated chewing gum tablets with high drug loadings." Journal of Texture Studies 49, no. 1 (2017): 30–37. http://dx.doi.org/10.1111/jtxs.12287.

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Rao.S, Kameswara, Yusuf MD., Saraswathi P., Ch R. Raghavendra Rao, Murali P., and Vijayakumar V. "Formulation and evaluation of orodispersible Enalapril maleate tablets: a comparative study on natural super disintegrents and synthetic super disintegrents." International Journal of Advances in Scientific Research 1, no. 7 (2015): 313. http://dx.doi.org/10.7439/ijasr.v1i7.1821.

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The aim of the present investigation is to formulate Enalapril maleate oral disintegrating tablet by using natural and synthetic superdisintegrents..ODTs may also be used to deliver drugs to the oral cavity, for local action or, in some cases, absorption across the oral mucosa, thereby avoiding first-pass hepatic metabolism and potentially increasing the rate and extent of uptake, and reducing undesirable metabolites. The objectives of the research work is to formulate oral disintegrating tablets of Enalapril maleate by using different super disintegrates(Natural, Synthetic) in different ratio
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Vijayalaxmi, Sepuri, and Abbaraju Krishna Sailaja. "Design, Formulation, and Optimization of Nicardipine-Loaded Gastroretentive Floating Microspheres: In-vitro, Ex-vivo and In-vivo Characterization." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1652–60. http://dx.doi.org/10.25258/ijddt.14.3.57.

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Nicardipine hydrochloride is highly soluble at low pH values. The objective of this investigation was to design, manufacture, and refine the drug’s floating microspheres to increase its bioavailability and prolong its period of residence in the gastrointestinal tract. To optimize the Box-Behken and prepare the floating microspheres, solvent evaporation was employed. The formulation F5 was discovered to be the best as anticipated by the design expert software’s point prediction. Evaluations of pre- and postcompressional parameters were conducted. Utilizing several kinetic models, the drug relea
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