Academic literature on the topic 'Posterior insula'

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Journal articles on the topic "Posterior insula"

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Türe, Uğur, Dianne C. H. Yaşargil, Ossama Al-Mefty, and M. Gazi Yaşargil. "Topographic anatomy of the insular region." Journal of Neurosurgery 90, no. 4 (1999): 720–33. http://dx.doi.org/10.3171/jns.1999.90.4.0720.

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Object. The insula is one of the paralimbic structures and constitutes the invaginated portion of the cerebral cortex, forming the base of the sylvian fissure. The authors provide a detailed anatomical study of the insular region to assist in the process of conceptualizing a reliable surgical approach to allow for a successful course of surgery.Methods. The topographic anatomy of the insular region was studied in 25 formalin-fixed brain specimens (50 hemispheres). The periinsular sulci (anterior, superior, and inferior) define the limits of the frontoorbital, frontoparietal, and temporal operc
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Tanriover, Necmettin, Albert L. Rhoton, Masatou Kawashima, Arthur J. Ulm, and Alexandre Yasuda. "Microsurgical anatomy of the insula and the sylvian fissure." Journal of Neurosurgery 100, no. 5 (2004): 891–922. http://dx.doi.org/10.3171/jns.2004.100.5.0891.

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Object. The purpose of this study was to define the topographic anatomy, arterial supply, and venous drainage of the insula and sylvian fissure. Methods. The neural, arterial, and venous anatomy of the insula and sylvian fissure were examined in 43 cerebral hemispheres. Conclusions. The majority of gyri and sulci of the frontoparietal and temporal opercula had a constant relationship to the insular gyri and sulci and provided landmarks for approaching different parts of the insula. The most lateral lenticulostriate artery, an important landmark in insular surgery, arose 14.6 mm from the apex o
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Rachidi, Inès, Lorella Minotti, Guillaume Martin, et al. "The Insula: A Stimulating Island of the Brain." Brain Sciences 11, no. 11 (2021): 1533. http://dx.doi.org/10.3390/brainsci11111533.

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Direct cortical stimulation (DCS) in epilepsy surgery patients has a long history of functional brain mapping and seizure triggering. Here, we review its findings when applied to the insula in order to map the insular functions, evaluate its local and distant connections, and trigger seizures. Clinical responses to insular DCS are frequent and diverse, showing a partial segregation with spatial overlap, including a posterior somatosensory, auditory, and vestibular part, a central olfactory-gustatory region, and an anterior visceral and cognitive-emotional portion. The study of cortico-cortical
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Kaneko, Nobuyuki, Warren W. Boling, Takaharu Shonai, et al. "Delineation of the Safe Zone in Surgery of Sylvian Insular Triangle: Morphometric Analysis and Magnetic Resonance Imaging Study." Operative Neurosurgery 70, suppl_2 (2011): ons290—ons299. http://dx.doi.org/10.1227/neu.0b013e3182315112.

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ABSTRACT BACKGROUND: Surgery within the insula carries significant risk of morbidity, particularly hemiparesis, because of the difficulty in detecting the internal capsule boundaries. OBJECTIVE: We analyzed the anatomy of the insula and identified landmarks anticipated to facilitate surgery for intrinsic insular lesions. METHODS: Insular region anatomy was studied in 11 cadaveric brains harvested within 72 hours postmortem. MRI of the specimens was acquired using 3.0 T with T2-weighting and 25 directions of diffusion tensor imaging. Landmarks easily recognizable during surgery were identified
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Martino, Juan, Francesco Vergani, Santiago Gil Robles, and Hugues Duffau. "New Insights Into the Anatomic Dissection of the Temporal Stem With Special Emphasis on the Inferior Fronto-occipital Fasciculus: Implications in Surgical Approach to Left Mesiotemporal and Temporoinsular Structures." Operative Neurosurgery 66, suppl_1 (2010): ons—4—ons—12. http://dx.doi.org/10.1227/01.neu.0000348564.28415.fa.

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Abstract Objective: To analyze the 3-dimensional relationships of the inferior fronto-occipital fasciculus (IFOF) within the temporal stem using anatomic dissection and to study the surgical application. Methods: Ten postmortem human hemispheres (5 right, 5 left) were dissected using the Klingler fiber dissection technique. The 3-dimensional relationships of the IFOF with different landmarks of the temporal stem, insula, and temporal lobe were analyzed and measured. Results: An average distance of 10.9 mm (range, 8–15 mm) was observed between the limen insulae and the anterior edge of the IFOF
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Baumgartner, Michael E., Samuel B. Tomlinson, Kathleen Galligan, and Benjamin C. Kennedy. "Motor Outcome After Posterior Insular Resection for Pediatric Epilepsy." Brain Sciences 15, no. 2 (2025): 177. https://doi.org/10.3390/brainsci15020177.

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The increasingly widespread use of stereo-EEG in the pre-surgical evaluation has led to greater recognition of the insula as both a source and surgical target for drug-resistant epilepsy. Clinicians have long appreciated the challenges of diagnosing and treating seizures arising from the insula. Insular-onset seizures present with a wide variety of semiologies due to its dense and complex integration with other brain structures, resulting in the insula’s reputation as the “great mimicker.” Surgical access to the insula is guarded by the overlying frontal, temporal, and parietal opercula and re
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Afif, Afif, Guillaume Becq, and Patrick Mertens. "Definition of a Stereotactic 3-Dimensional Magnetic Resonance Imaging Template of the Human Insula." Operative Neurosurgery 72, no. 1 (2012): ons35—ons46. http://dx.doi.org/10.1227/neu.0b013e31826cdc57.

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Abstract Background: This study proposes a 3-dimensional (3-D) template of the insula in the bicommissural reference system with posterior commissure (PC) as the center of coordinates. Objective: Using the bicommissural anterior commissure (AC)-PC reference system, this study aimed to define a template and design a method for the 3-D reconstruction of the human insula that may be used at an individual level during stereotactic surgery. Methods: Magnetic resonance imaging (MRI)-based morphometric analysis was performed on 100 cerebral cortices with normal insulae based on a 3-step procedure: St
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Parellada, M., L. Pina-Camacho, C. Moreno, et al. "Insular pathology in young people with high-functioning autism and first-episode psychosis." Psychological Medicine 47, no. 14 (2017): 2472–82. http://dx.doi.org/10.1017/s0033291717000988.

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BackgroundAutism Spectrum Disorders (ASD) and psychosis share deficits in social cognition. The insular region has been associated with awareness of self and reality, which may be basic for proper social interactions.MethodsTotal and regional insular volume and thickness measurements were obtained from a sample of 30 children and adolescents with ASD, 29 with early onset first-episode psychosis (FEP), and 26 healthy controls (HC). Total, regional, and voxel-level volume and thickness measurements were compared between groups (with correction for multiple comparisons), and the relationship betw
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Türe, Uğur, M. Gazi Yaşargil, Ossama Al-Mefty, and Dianne C. H. Yaşargil. "Arteries of the insula." Journal of Neurosurgery 92, no. 4 (2000): 676–87. http://dx.doi.org/10.3171/jns.2000.92.4.0676.

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Object. The insula is located at the base of the sylvian fissure and is a potential site for pathological processes such as tumors and vascular malformations. Knowledge of insular anatomy and vascularization is essential to perform accurate microsurgical procedures in this region.Methods. Arterial vascularization of the insula was studied in 20 human cadaver brains (40 hemispheres). The cerebral arteries were perfused with red latex to enhance their visibility, and they were dissected with the aid of an operating microscope.Arteries supplying the insula numbered an average of 96 (range 77–112)
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Liang, Despoina, and Charalampos Labrakakis. "Multiple Posterior Insula Projections to the Brainstem Descending Pain Modulatory System." International Journal of Molecular Sciences 25, no. 17 (2024): 9185. http://dx.doi.org/10.3390/ijms25179185.

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The insular cortex is an important hub for sensory and emotional integration. It is one of the areas consistently found activated during pain. While the insular’s connections to the limbic system might play a role in the aversive and emotional component of pain, its connections to the descending pain system might be involved in pain intensity coding. Here, we used anterograde tracing with viral expression of mCherry fluorescent protein, to examine the connectivity of insular axons to different brainstem nuclei involved in the descending modulation of pain in detail. We found extensive connecti
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Dissertations / Theses on the topic "Posterior insula"

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Paiva, Joselisa Péres Queiroz de. "Efeitos da inativação temporária do córtex insular anterior e posterior no condicionamento de medo ao contexto e ao som em ratos." reponame:Repositório Institucional da UFABC, 2015.

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Orientadora: Profª Drª Raquel Vecchio Fornari<br>Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Neurociência e Cognição, 2015.<br>O cortex insular (CI), ou insula, conquistou nos ultimos anos um lugar de destaque na area cientifica por seu suposto envolvimento em processos emocionais e cognitivos. No rato, como nos seres humanos, o CI pode ser dividido em duas sub-regioes funcionalmente heterogeneas. Embora a maioria dos estudos realizados em animais tenha mostrado um envolvimento da regiao mais rostral (CI anterior) na memoria gustativa, outros sugerem um p
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Sawamoto, Nobukatsu. "Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulate cortex and parietal operculum/posterior insula : an event-related functional magnetic resonance imaging study." Kyoto University, 2001. http://hdl.handle.net/2433/150507.

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Bouchatta, Otmane. "Sensibilisation à la douleur chez un modèle murin de troubles du déficit de l'attention et de l'hyperactivité." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0356/document.

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L’ADHD (Attention-deficit/hyperactivity disorder) est une maladie du développement caractérisée par l’impulsivité, l’hyperactivité, et l’inattention. Les voies neuronales impliquées dans ces déficits indiquent des dysfonctionnements dans les réseaux catécholaminergiques frontal-sous-corticaux, impliquant l'innervation dopaminergique et noradrénergique. Des études récentes ont mis en évidence une hypersensibilité à la douleur chez les patients ADHD et soulignent une possible comorbidité entre l’ADHD et la douleur. Cependant, les mécanismes et les circuits neuraux impliqués dans ces interactions
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Bou, Sader Nehme Sarah. "Cortical mechanisms of comorbidity between pain sensitization and attention-deficit/hyperactivity disorder (ADHD) in a mouse model." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0488.

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Le trouble du déficit de l'attention avec ou sans hyperactivité (TDAH) et la douleur chronique sont deux syndromes complexes d’origine multifactorielle. Des études confirment une comorbidité entre ces deux pathologies. Cependant, les mécanismes ne sont toujours pas élucidés. Une hyperactivité des neurones de l’ACC et une dérégulation de la voie ACC-insula postérieure (PI) ont été démontrées dans un modèle de souris TDAH. La neuroinflammation serait impliquée dans cette concomitance. Notre hypothèse suggère que la neuroinflammation déclencherait une amplification de l’activité neuronale dans l’
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Thiaucourt, Margot [Verfasser], and Gabriele [Akademischer Betreuer] Ende. "Magnetresonanzspektroskopie der posterioren Insula - Korrelation von GABA und Glutamat mit der Schmerzsensibilität bei Patientinnen mit Borderline Persönlichkeitsstörung und gesunden Kontrollen / Margot Thiaucourt ; Betreuer: Gabriele Ende." Heidelberg : Universitätsbibliothek Heidelberg, 2019. http://d-nb.info/119910907X/34.

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Ferrier, Jeremy. "Douleurs neuropathiques induites par l'oxaliplatine. Physiopathologie et approches thérapeutiques." Thesis, Clermont-Ferrand 1, 2013. http://www.theses.fr/2013CLF1PP06/document.

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L’oxaliplatine, anticancéreux utilisé pour le traitement du cancer colorectal, est responsable d’une neurotoxicité périphérique dose-limitante affectant une grande majorité de patients. La neurotoxicité de l’oxaliplatine se présente sous deux formes : une forme immédiate, se traduisant par des paresthésies transitoires, et une forme retardée et cumulative, caractérisée par l’apparition d’une neuropathie périphérique douloureuse fortement invalidante. A l’heure actuelle, la prise en charge des douleurs neuropathiques est souvent incomplète, principalement à cause du manque de traitements effica
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Yeh, Han-Yuan, and 葉瀚元. "The Role of Posterior Insular Cortex in Rat Model of Neuropathic Pain." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/42719224738618799550.

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碩士<br>國立臺灣大學<br>動物學研究所<br>101<br>Neuropathic pain is an intractable disease in daily life and clinical research. It can result in long-term changes in central nervous system. Insular cortex is a brain region participated in processing of different sensory modalities. Evidences have also shown that posterior insular cortex may be related to somatosensory perception especially in nociception. However, the role for how PIC contributes to the initiation or maintenance of neuropathic pain is less understood. In the present study, permanent lesion by NMDA excitotoxicity in PIC was used to assess the
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Books on the topic "Posterior insula"

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Wilshire, Carolyn E. Conduction Aphasia: Impaired Phonological Processing. Edited by Anastasia M. Raymer and Leslie J. Gonzalez Rothi. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199772391.013.8.

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Conduction aphasia is a syndrome characterized by impaired repetition in the context of relatively preserved auditory comprehension and fluent speech. The classical conceptualization of conduction aphasia as a disconnection syndrome has been undermined in recent years. Nevertheless, this diagnosis delineates a small subset of individuals with aphasia who have many common cognitive and anatomical characteristics. Conduction aphasia is associated with damage to a relatively narrow and well-defined group of left hemisphere brain structures, which may include the posterior superior temporal lobe,
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Wittmann, Marc, and Karin Meissner. The embodiment of time: How interoception shapes the perception of time. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198811930.003.0004.

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Within the framework of the embodiment of time, this chapter presents accumulating evidence of how interoception and associated brain networks process time. Functional MRI studies have shown that climbing neural activation in the posterior insular cortex correlates with stimulus duration in a time-estimation task in the multiple-second range. Given the close connection between the insular cortex and ascending body signals, the authors suggest that the accumulation of physiological changes in body states is the basis for the subjective impression of duration. Psychophysiological findings reveal
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Dixon, Sharon, and Sophie Roberts. Orthotics. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199533909.003.0017.

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An orthotic is a custom-made insole which fits inside a shoe with the purpose of changing the way in which the foot functions during both standing and dynamic gait. There are many theories regarding the influence of these devices on the foot and lower limb. It is widely accepted that the fundamental principle is that an orthotic encourages a change in the movement pattern of the foot, aiming to alleviate stress to musculoskeletal structures, and produce changes in muscle firing patterns. An example of how an orthotic works is when one is used to change the functioning position of the medial lo
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Kendall, Tim. ‘Freely Proffered’? Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198806516.003.0008.

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Writing The Times obituary for Rupert Brooke, Winston Churchill, then First Lord of the Admiralty, contended that in times of crisis ‘no sacrifice but the most precious is acceptable, and the most precious is that which is most freely proffered’. In an age when faith in an afterlife was waning, a freely proffered sacrifice appeared especially virtuous. To praise it was, paradoxically, to insult it—hence the soldier’s insistence, in Brooke’s most famous sonnet, that posterity should remember him strictly according to his own stipulations: ‘think only this of me’. Brooke was a pioneer, understan
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Book chapters on the topic "Posterior insula"

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Allardyce, Thomas J., Giles R. Scuderi, and John N. Insall. "The Insall-Burstein® Posterior Stabilized Condylar Knee Prosthesis." In Surgical Techniques in Total Knee Arthroplasty. Springer New York, 2002. http://dx.doi.org/10.1007/0-387-21714-2_8.

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Gerrans, Philip. "Depersonalization disorder." In Anatomy of an Avatar. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/9780191994395.003.0005.

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Abstract In depersonalization disorder, patients feel detached from experience and report feeling ‘as if’ experience is not happening to them. There is no deficit of cognition or interoception, but there is a characteristic flattening or absence of affective feeling.The nature of the avatar as an anchor of allostatic inference, neurally realized by circuitry centred on the insula, provides an explanation. The posterior insula is a hub of bodily self modelling. The anterior insula is a hub that: (1) integrates bodily signals with higher-level cognitive and emotional processing and (2) in the pr
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Craig, A. D. (Bud). "Bodily Feelings Emerge in the Insular Cortex." In How Do You Feel? Princeton University Press, 2014. http://dx.doi.org/10.23943/princeton/9780691156767.003.0006.

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This chapter presents evidence that supports the idea that activity in the interoceptive cortex in the posterior insula is re-represented, integrated, and transformed in the middle and anterior portions of human insular cortex to generate the feelings that one experiences. It also explains how vivid feelings are generated in a model of interoceptive integration that engenders homeostatic sentience. The emergence of bodily feelings provides the foundation for the generation of emotional feelings in the anterior insular cortex as if they are feelings from the body. The chapter then describes the
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Job-Chapron, Anne-Sophie, Lorella Minotti, Dominique Hoffmann, and Philippe Kahane. "SEEG in Temporal Lobe Epilepsy." In Invasive Studies of the Human Epileptic Brain, edited by Samden D. Lhatoo, Philippe Kahane, and Hans O. Lüders. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198714668.003.0021.

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In the context of temporal lobe epilepsy (TLE), there are different scenarios where a stereo-electroencephalographic (SEEG) study must be strongly considered. This chapter reviews these situations, which include bitemporal epilepsy, unilateral lesional and non-lesional TLE, temporal ‘plus’ epilepsy (TPE), and pseudo-TLE. It also emphasizes why SEEG is especially appropriate to adequately sample all possible ictal generators, either temporal (amygdala, hippocampus, entorhinal cortex, or temporal neocortex) or extratemporal (insula, orbitofrontal cortex, or posterior cingulate gyrus). It include
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Benarroch, Eduardo E. "Executive Control." In Neuroscience for Clinicians, edited by Eduardo E. Benarroch. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190948894.003.0042.

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Attention, working memory, decision-making, and executive control are fundamental cognitive functions that involve large-scale networks largely defined on the basis of functional magnetic resonance imaging (fMRI) studies. These networks include areas of the lateral and medial prefrontal, orbitofrontal, anterior, and midcingulate cortices, anterior insula, and lateral and medial posterior parietal cortices as well as areas of the temporal lobe and temporoparietal junction. These networks include the dorsal and ventral attention networks, frontoparietal, cingulo-opercular and salience control ne
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Li, Xiujun, Zhenglong Lin, and Jinglong Wu. "Language Processing in the Human Brain of Literate and Illiterate Subjects." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2013. http://dx.doi.org/10.4018/978-1-4666-2113-8.ch021.

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Using functional magnetic resonance imaging (fMRI) or positron emission tomography (PET), much knowledge has been gained in understanding how the brain is activated during controlled experiments of language tasks in educated healthy subjects and in uneducated healthy subjects. While previous studies have compared performance between alphabetic subjects, few data were about Chinese-speaking individuals. In alphabetic subjects, studies indicate that the literates surpass the illiterates, especially in tasks involving phonological processing, and that different activation regions in fMRI are loca
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"49 Posterior Peri-insular Quadrantotomy." In Pediatric Epilepsy Surgery, edited by Oğuz Çataltepe and George I. Jallo. Georg Thieme Verlag, 2019. http://dx.doi.org/10.1055/b-0039-171681.

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Keller, Thomas, and Mark Miller. "Posterior Cruciate Ligament Reconstruction." In Insall &amp Scott Surgery of the Knee. Elsevier, 2012. http://dx.doi.org/10.1016/b978-1-4377-1503-3.00056-1.

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Fanelli, Gregory C. "Posterior Cruciate Ligament Reconstruction." In Insall &amp Scott Surgery of the Knee. Elsevier, 2012. http://dx.doi.org/10.1016/b978-1-4377-1503-3.00057-3.

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Kim, Sung-Jae, and Sung-Hwan Kim. "Posterior Cruciate Ligament Reconstruction." In Insall &amp Scott Surgery of the Knee. Elsevier, 2012. http://dx.doi.org/10.1016/b978-1-4377-1503-3.00058-5.

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Conference papers on the topic "Posterior insula"

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Dosualdo, Caique Alberto. "Reversible posterior encephalopathy syndrome as a rare complication of oxaliplatin chemotherapy: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.399.

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Introduction: The reversible posterior encephalopathy syndrome corresponds to a clinical and radiological diagnosis marked by headache, altered mental status, reduced visual acuity and seizures, associated with vasogenic edema mainly in posterior white matter. It presents a large heterogeneity of etiologies, such as cytotoxic drugs, eclampsia, vasculitis, and nephropathies, with arterial hypertension being the most important. In that way, quick diagnostic investigation is necessary to provide a better prognosis. Case report: Case report of a patient who was in adjuvance combined chemotherapy,
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Sodre, Maria Eduarda Japyassu, Maria Izabel Wanderley Bezerra, Juliana Oliveira Costa, Diego Shelman de souza Rosado Amaral, Vinicius Guedes Lima Bahia, and Maria Isabel Dantas Bezerra Lyra. "Association between religious practices impact on cerebral neurophysiology and radiological expression: a systematic review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.667.

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Introduction: Debates around the correlation between neurophysiological processes and religious habits have gained ground in the research in neuroscience. Objective: To evaluate the impact of religious practices on brain physiology and correlate such behaviors and neuroimaging. Design and setting: It’s a systematic review without metanalysis in PUBMED database. Method: Data carried out in the period 2009 and 2020. Descriptors used: “neural correlates of religious, mystical experience” and “religious belief and neuroimaging”, combined with the Boolean operator “and”. Results: It was noted that
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Teixeira, Igor de Lima e., Marina Battaglini, Tarcisio Alvarenga, and Patrick Sousa Santos. "Descartes’ error”: evidences for the role of brain regions and their connections in introspective thoughts and self-identity." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.668.

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Introduction: René Descartes was a French philosopher, considered the father of rationalism and one of the most important thinkers in history. Based on his methodical doubts’ technique, the author concluded that he exists as a thinking thing, that if “I think, therefore I am”. He establishes that he had no more doubts that he really existed as thought and as a body, however, he could not think that thought and body were two equal substances, since they had certain different properties, therefore, the author came to believe that mind and body were distinct substances. Since the 17th century, ad
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Lemos, Ana Flavia Andrade Ana Flavia Andrade, Helio Aquaroni Farão Gomes, Patrick Emanuell Mesquita Sousa Santos, et al. "PRES in the context of an infectious insult." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.683.

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Introduction: Posterior reversible leukoencephalopathy syndrome is an acute/subacute clinical-radiological syndrome characterized by headache, changes in consciousness, seizures, focal neurological deficits, visual deficits and that may be preceded by uncontrolled blood pressure in the day before. It does not commonly occur concomitantly with prolonged infectious conditions. The most typical imaging finding is white matter edema in the posterior cerebral hemispheres. Treatment is based on adequate control of blood pressure and epileptic seizures, as well as metabolic and electrolyte control. T
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Petrella, Anthony J., Alexandros Karmas, Richard C. Berger, Harry E. Rubash, and Mark C. Miller. "The Effect of PCL Substitution on Patellofemoral Joint Forces and A/P Drawer in the Post-TKA Knee." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0146.

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Abstract The decision to retain the posterior cruciate ligament (PCL) in total knee arthroplasty (TKA) is an issue of some debate. The use of a PCL substituting prosthesis relieves the surgeon of the task of properly tensioning the PCL and allows better surgical exposure (Scuderi and Insall, 1989). Moreover, in vitro studies of post-TKA PCL strain (Incavo et al., 1994) as well as clinical studies of TKA function (Worland et al., 1997) have failed to show a significant difference between PCL retaining and substituting knees. In some cases, however, patellofemoral joint (PFJ) complications such
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Sigal, Ian A., Hongli Yang, Michael D. Roberts, Claude F. Burgoyne, and J. Crawford Downs. "Biomechanics of the Posterior Pole During the Remodeling Progression From Normal to Early Experimental Glaucoma." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206518.

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Glaucoma is one of the leading causes of blindness worldwide. The loss of vision associated with glaucoma is due to damage to the retinal ganglion cell axons, which transmit visual information to the brain. Damage to these axons is believed to occur as the axons pass through the lamina cribrosa (LC), a connective tissue structure in the optic nerve head at the back of the eye. Elevated intraocular pressure (IOP) has been identified as the main risk factor for the development of the neuropathy, but the mechanism(s) by which a mechanical insult (elevated IOP) is translated into a biological effe
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Kodiyalam, Sanjay, Michael D. Roberts, Ian A. Sigal, Richard T. Hart, Claude F. Burgoyne, and J. Crawford Downs. "Large Scale Voxel-Based Finite Element Modeling of Normal and Early Glaucomatous Monkey Lamina Cribrosa." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192984.

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Glaucoma is a leading cause of blindness worldwide. Some of the chief clinical hallmarks of glaucoma are the permanent posterior cupping of the optic nerve head, in the posterior pole of the eye, and the accompanying damage to the lamina cribrosa — the fenestrated structure of connective tissue spanning the scleral canal that provides structural support to the axon bundles passing through it. While elevated intraocular pressure (IOP) is associated with this disease, its role remains unclear. It has been hypothesized that IOP-related stress and strain within the laminar connective tissue (LCT)
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Kiriakidis, Kiriakos. "Particle Filter for Plasma Insulin Estimation." In ASME 2010 Dynamic Systems and Control Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/dscc2010-4179.

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Bergman’s Minimal Model (MM) captures simply but accurately the homeostasis of glucose and insulin in plasma. The MM has been proposed as an estimator of insulin for Diabetes Mellitus. Along this line of research, the present work takes into account the error between Bergman’s simple compartmental model and the complex physiologic system it depicts. The author employs a Particle Filter (PF) in order to construct the posterior probability density of insulin from data. As a sequential Bayesian estimator, the PF can handle nonlinear state equations, such as the MM, as well as non-Gaussian modelin
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Sosa García, Omar. "Fragmentos de identidad insular: paisaje y cultura local como herramientas para la planificación turística de Agaete y Alghero." In Seminario Internacional de Investigación en Urbanismo. Curso de Arquitetura e Urbanismo. Universidade do Vale do Itajaí, 2016. http://dx.doi.org/10.5821/siiu.6351.

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Algunas ciudades históricas costeras, con cierto potencial de desarrollo turístico y arraigadas tradiciones culturales, necesitan una planificación adecuada para afrontar dicho desarrollo. La sobreexplotación de la franja costera impulsa el deterioro de los valores que la hacen diferentes de otros territorios, razón básica de su posible atractivo turístico. Así, bajo la consideración de que la cultura local y el paisaje están intrínsecamente unidos, influencian el evolución de dichas ciudades y territorios y pueden ser la base de un desarrollo turístico ambiental y socialmente sostenible, se p
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Aversa, María, and Pablo Del Río. "PUESTA EN VALOR DEL ESPACIO RIBEREÑO EN LOCALIDADES RURALES: Proyectos de paisaje en el partido de Alberti, provincia de Buenos Aires, Argentina." In Seminario Internacional de Investigación en Urbanismo. Universitat Politècnica de Catalunya, Grup de Recerca en Urbanisme, 2024. http://dx.doi.org/10.5821/siiu.12637.

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The work presents a portfolio of landscape project ideas to value public river space in the Alberti district, Province of Buenos Aires. The territory of action is cut to rural localities linked to the Salado River and its tributaries contained by two main roads of national and provincial connectivity. As a result, a portfolio with fifteen project ideas was obtained that prefigures a comprehensive intervention strategy for the riverside space and nearby towns and, later, the evaluation carried out by the specialists in charge of the study and the municipal actors. With this input, four project
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