Log in

Relevant bibliographies by topics / Potassium channel openers / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Potassium channel openers.

Dissertations / Theses on the topic 'Potassium channel openers'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 24 dissertations / theses for your research on the topic 'Potassium channel openers.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Neill, Colin Gardner. "Synthesis of pyridothiadiazine dioxides as potential potassium ion channel openers." Thesis, Heriot-Watt University, 1995. http://hdl.handle.net/10399/1347.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Kirby, Robert William. "Investigation of the pharmacophore of BK[ca] potassium channel openers." Thesis, Sheffield Hallam University, 2008. http://shura.shu.ac.uk/19920/.

Full text

Abstract:

Large conductance voltage-activated calcium-sensitive potassium channels (BK[ca]) are fundamental in the control of cellular excitability which is critical in the regulation of many physiological processes. Agents that activate the channel (openers) have been proposed to be potential therapeutics for a number of un-met clinical conditions. Several heterogeneous classes of compounds have been described as BK[ca] channel openers and preliminary pharmacophore data has arisen for synthetic molecules based on the structure of benzimidazolones. The project aimed to explore a series of novel compound

APA, Harvard, Vancouver, ISO, and other styles

3

Zhang, Hailin. "ATP-sensitive potassium channels and their modulation by nucleotides and potassium channel openers in vascular smooth muscle cells." Thesis, St George's, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309744.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Bailey, Elizabeth Helen. "An investigation into the combination of nifedipine with potassium channel openers as potential tocolytic therapy for preterm labour, and a novel potassium channel blocker as potential therapy for post-partum haemorrhage." Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/78668/.

Full text

Abstract:

Background Preterm labour and post-partum haemorrhage are leading causes of pregnancy morbidity and mortality. Previous work identified potassium channels expressed in myometrium and hypothesized modulation of channels with greater expression in MSMC than VSMC will influence contractility and avoid cardiovascular effects. By combining calcium channel blockers with potassium channel openers an enhanced tocolytic effect is anticipated. VU590 inhibits Kir 7.1 and it was hypothesised would elicit a contractile effect with therapeutic potential for post-partum haemorrhage. Aim To determine the effe

APA, Harvard, Vancouver, ISO, and other styles

5

Amberg, Gregory C. "A-type potassium currents in gastrointestinal smooth muscle /." abstract and full text PDF (UNR users only), 2002. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3060369.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Tichenor, Jennifer Noel. "Stretch-activated potassium channels in human myometrium and aspects of cGMP signaling." abstract and full text PDF (UNR users only), 2008. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3316375.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Hagen, Brian M. "Regulation of calcium-activated potassium channels by localized calcium transients in murine colon." abstract and full text PDF (free order & download UNR users only), 2005. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3209955.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Sigal, Yaron M. "Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3339204.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Ryan, Devon P. "Characterization of a novel inwardly rectifying potassium channel (Kir2.6) and its role in thyrotoxic hypokalemic periodic paralysis." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2010. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3398884.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Abu, Baker Salah. "Molecular and functional identification of the two-pore K+ channels in bladder smooth muscle." abstract and full text PDF (UNR users only), 2008. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3320570.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Hallahan, Brent J. "The role of tyrosine kinases and calcineurin in the calcium-mediated modulation of the voltage-gated potassium channel, Kv1.1." [Bloomington, Ind.] : Indiana University, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3207050.

Full text

Abstract:

Thesis (Ph.D.)--Indiana University, Dept. of Neuroscience, 2006.<br>Source: Dissertation Abstracts International, Volume: 67-01, Section: B, page: 0118. Adviser: Joseph Farley. "Title from dissertation home page (viewed Feb. 22, 2007)."

APA, Harvard, Vancouver, ISO, and other styles

12

Flynn, Elaine Rose Maria. "Ionic conductances involved in the electrical activity of the canine gastrointestinal tract /." abstract and full text PDF (UNR users only), 1999. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:9934138.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Ro, Seungil. "SK channels : distribution, function and regulation in mouse colonic myocytes /." abstract and full text PDF (UNR users only), 2002. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3090879.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Wen-Sheng and 蔡文盛. "The effect of potassium channel openers on the myotonia of mouse skeletal muscle." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/41693856640680381038.

Full text

Abstract:

碩士<br>中山醫學大學<br>生物醫學科學學系碩士班<br>100<br>The purpose of this study was to investigate the effect of KCNQ (potassium channel, voltage-gated, KQT-like subfamily) openers in preventing myotonia caused by anthracene-9-carboxylic acid (9-AC, a chloride channel blocker). Myotonia is a neuromuscular disorder and characterized by the membrane hyperexcitability and slow relaxation of muscles after a contraction. An animal model of myotonia can be elicited in murine skeletal muscle by 9-AC treatment. Retigabine, flupirtine and lidocaine can inhibit the increased twitch amplitude (0.1 Hz stimulation) and re

APA, Harvard, Vancouver, ISO, and other styles

15

LIN, YEN-CHUNG, and 林燕君. "Synthesis and Pharmacology of Tricyclic 1-Benzopyrano[3,4-b][1,4]Oxazine Derivatives as Potassium Channel Openers." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/06973483504569290979.

Full text

Abstract:

碩士<br>國立臺灣大學<br>藥學研究所<br>87<br>As rigid analogs of the prototype potassium channel opener (POC) cromakalim, a series of optically active hexahydro benzopyrano[3,4-b][1,4] oxazine derivatives have been synthesized. The PCO activity of target compounds were evaluated in vitro with preparations of spontaneous contracting rat portal vein and KCl-stimulated rat detrusor strip. Target compounds (+)-37a-c are acylation products of (4aR,10aS)-1,2,3,4a,5,10b-hexahydro-5,5-dimethyl-1-benzopyrano[3,4-b][1,4] oxazine-9-carbonitrile ((+)-41). The starting epoxide (-)-39, prepared form 6-cyano-

APA, Harvard, Vancouver, ISO, and other styles

16

Davies, Gareth C., M. Julie Thornton, Tracey J. Jenner, et al. "Novel and established potassium channel openers stimulate hair growth in vitromodes of action in hair follicles.: implications for their." 2005. http://hdl.handle.net/10454/4017.

Full text

Abstract:

No<br>Although ATP-sensitive potassium (K(ATP)) channel openers, e.g., minoxidil and diazoxide, can induce hair growth, their mechanisms require clarification. Improved drugs are needed clinically. but the absence of a good bioassay hampers research. K(ATP) channels from various tissues contain subtypes of the regulatory sulfonylurea receptor, SUR, and pore-forming, K(+) inward rectifier subunits, Kir6.X, giving differing sensitivities to regulators. Therefore, the in vitro effects of established potassium channel openers and inhibitors (tolbutamide and glibenclamide), plus a novel, selective

APA, Harvard, Vancouver, ISO, and other styles

17

Chiu, Hsin-I., and 邱欣怡. "(I)I. Synthesis of Tricyclic [1]Benzopyrano[3,4-b][1,4]Oxazines as Bladder-selective Potassium Channel Openers.(II)Synthesis of D-chiro-Inositol Derivatives as Insulin Mimetics." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/25181663020983877074.

Full text

Abstract:

博士<br>國立臺灣大學<br>藥學研究所<br>89<br>Abstract I. Synthesis of Tricyclic [1]Benzopyrano[3,4-b][1,4]Oxazines as Bladder-selective Potassium Channel Openers. Based on the prototype potassium channel opener (PCO) , cromakalim, a series of optically active tricyclic [1]benzopyrano[3,4-b][1,4]oxazines（16，19-24，25-26，28）have been synthesized. Also synthesized were (2S,3'S,4'R)-N-(6-cyano-3,4-dihydro-2,2-dimethyl-3-hydroxy-2H-[1]benzopyran-4-yl)-2-trifluoromethylpropamide (29) and (2R,3'S,4'R)-N-(6-cyano-3,4-dihydro-2,2-dimethyl-3-hydroxy-2H-[1]benzopyran-4-yl)-2-trifluoromethylpropam

APA, Harvard, Vancouver, ISO, and other styles

18

Liang, Pi-Hui, and 梁碧惠. "1. Synthesis and Pharmacology of N-Arylated Pyrrolidin-2-ones and Morpholin-3-ones as Potassium Channel Openers, 2. 2. Synthesis and Pharmacology of Galanthamine Analogs as Potential Agents for the Treatment of Alzheimer’s Disease." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/03739443088319720474.

Full text

Abstract:

博士<br>國立臺灣大學<br>藥學研究所<br>91<br>1. Synthesis and pharmacology of N-arylated pyrrolidin-2-ones and morpholin-3-ones as potassium channel openers (-)-N-(4-Benzoylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide (ZD6169, (-)-1) was recently reported to be a novel potassium channel opener (KCO), which significantly reduced micturition frequency in rats (ED50 = 0.16 mg/kg) with minimal effect on cardiovascular parameters (ED20 = 30 mg/kg). In our search for tissue-selective KCOs, N-(arylated)-1,3-oxazolidin-2,4-dione 2, morpholin-3-ones 3 - 5, pyrrolidin-2-ones 7 - 13, have been synt

APA, Harvard, Vancouver, ISO, and other styles

19

Shih-Chieh, Chang, and 張世杰. "Synthesis and Structure Activity Relationship of Benzopyran Potassium Channel Opener." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/75746098827301373212.

Full text

Abstract:

碩士<br>中國文化大學<br>應用化學研究所<br>88<br>Abstract Cardiovascular disease (CVD) has been a menace to the folks for a long time. According to the report of the Department of Health, among the top ten list of fatal causes to the folks'' death in the 88th R.O.C calendar, CVD and heart disease took the third and forth places respectively, and hypertension tenth. Therefore, developing an anti CVD medicine becomes a prime issue in the present time. Ion channel plays an important role in physiological functions. Since Noma found potassium ion channel in 1983, its wide effects

APA, Harvard, Vancouver, ISO, and other styles

20

Liu, Pei-Hsun, and 劉沛勳. "The protective effect of Kv7 potassium channel opener on myotonia, epilesy and myocardical ischemia reperfusion injury." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/74n627.

Full text

Abstract:

碩士<br>中山醫學大學<br>生物醫學科學學系碩士班<br>106<br>The Kv7 (KCNQ) potassium channel opener acts on the voltage-gated potassium channel to stabilize membrane potential. Recently, Kv7 potassium channel opener is a new target of drug development. In clinical, Kv7 potassium channel opener is used on the treatment of epilepsy, arrhythmia and neuropathic pain. ML213 and Retigabine are known Kv7 potassium channel opener at present. In this study, we investigated the protective effect of Kv7 potassium channel opener, ML213, Retigabine and the derivatives of Retigabine #8692 and #5540, on in vitro phrenic nerve-dia

APA, Harvard, Vancouver, ISO, and other styles

21

Jahromi, Babak S. "Potassium channels and cerebral vasospasm." 2003. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3097120.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Chen, Mei-jung, and 陳玫蓉. "Effects of CL-065, a newly synthesized ATP-dependent potassium channel opener, on cardiovascular functions on rats." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/38867273665309348242.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Peng, Yan Yan, and 彭嚴燕. "Effects of MJ355, a newly synthesized ATP-dependent potassium channel opener, on hemodynamics and myocardial ischemia-reperfusion injury in rats." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/45921699380214511650.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Haass, Friederike A. "Identification of yeast proteins necessary for cell surface function of a potassium channel." Diss., 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3289302.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!