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Journal articles on the topic 'Potassium phthalimide'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Nagel, N., H. Bock, and J. W. Bats. "Potassium Phthalimide." Acta Crystallographica Section C Crystal Structure Communications 52, no. 6 (1996): 1344–46. http://dx.doi.org/10.1107/s0108270196002387.

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2

Basu, Souradeep, Alexander H. Sandtorv, and David R. Stuart. "Imide arylation with aryl(TMP)iodonium tosylates." Beilstein Journal of Organic Chemistry 14 (May 11, 2018): 1034–38. http://dx.doi.org/10.3762/bjoc.14.90.

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Herein, we describe the synthesis of N-aryl phthalimides by metal-free coupling of potassium phthalimide with unsymmetrical aryl(TMP)iodonium tosylate salts. The aryl transfer from the iodonium moiety occurs under electronic control with the electron-rich trimethoxyphenyl group acting as a competent dummy ligand. The yields of N-aryl phthalimides are moderate to high and the coupling reaction is compatible with electron-deficient and sterically encumbered aryl groups.

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3

Ogurtsov, Vladimir A., and Oleg A. Rakitin. "8,18-Dithia-1,4,11,14-tetraazapentacyclo[11.7.0.03,11.05,9.015,19]icosa-3,5(9),6,13,15(19),16-hexaene-10,20-dione." Molbank 2019, no. 2 (2019): M1056. http://dx.doi.org/10.3390/m1056.

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4H-3λ2-Thieno[3,2-d]pyrimidin-4-one derivatives are of interest as biologically active compounds. In this communication, 2-(chloromethyl)-4H-3λ2-thieno[3,2-d]pyrimidin-4-one (1) was investigated in the reaction with ammonia, potassium phthalimide, and other basic agents. The dimerization product—8,18-dithia-1,4,11,14-tetrazapentacyclo[11.7.0.03,11.05,9.015,19]icosa-3,5(9),6,13,15(19),16-hexaene-10,20-dione was formed in the reaction with potassium phthalimide in DMF, by heating at 110 °C for 5 h. The structure of the newly synthesized compound was established by means of elemental analysis, hi

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4

Mercer, Frank W. "Synthesis and characterization of aromatic poly(ether ketone amide)s." High Performance Polymers 5, no. 3 (1993): 187–96. http://dx.doi.org/10.1088/0954-0083/5/3/002.

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A general method for the preparation of amide-containing aromatic polyether ketones has been developed. Polymerization is based on a ketone-activated halo displacement in amide-containing bis(4-fluorobenzoyl) moieties by phenoxides. N,N-Bis[4-(4-fluorobenzoyl)-(4-phenoxyphenylJ]terephthalamide and 4-[(4-fiuorobenzoyl)-(4-phenoxyphenylcarbamoyl)]-N-[(4-fluorobenzoyl)-(4-phenoxyphenyl)]phthalimide were prepared by reaction of 4-fluoro-benzoyl chloride with N,N.bis(4-phenoxyphenyl)terephthalamide and 4-(4.phenoxy-phenylcarbamoyl)-N-(4-phenoxyphenyl)phthalimide, respectively, in dichloromethane in

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5

Takahashi, Hiroki. "N-(4-Methoxybenzyl)phthalimide: a triclinic polymorph." Acta Crystallographica Section E Structure Reports Online 68, no. 8 (2012): o2457—o2458. http://dx.doi.org/10.1107/s1600536812031376.

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The title compound [systematic name: 2-(4-methoxybenzyl)isoindoline-1,3-dione], C16H13NO3, represents a triclinic polymorph of the previously reported monoclinic form [Warzechaet al.(2006).Acta Cryst. E62, o5450–o5452]. The reaction of potassium phthalimide and 4-methoxybenzyl chloride in dimethylformamide gave platelet-shaped crystals; these were harvested and then needle-shaped crystals were deposited. The platelet- and needle-shaped crystals correspond to the triclinic and monoclinic forms, respectively. The N—C—Car—Cartorsion angles between the ring systems are −82.66 (14) and 95.28 (13)°,

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6

Tibebu, Berihun, Abdudin Geremu, and Endale Tsegaye. "DFT Study on Potassium Benzene Disulfonamide and Potassium Phthalimide Ionic Liquid Based Carbon Dioxide Absorption." International Journal of Computational and Theoretical Chemistry 13, no. 1 (2025): 25–42. https://doi.org/10.11648/j.ijctc.20251301.13.

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This groundbreaking research rigorously investigated the CO&lt;sub&gt;2&lt;/sub&gt; absorption potential of two potassium-based ionic liquids (ILs), namely potassium benzene disulfonamide [C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;4&lt;/sub&gt;KNS&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;4&lt;/sub&gt;] and potassium phthalimide [C&lt;sub&gt;8&lt;/sub&gt;H&lt;sub&gt;4&lt;/sub&gt;KNO&lt;sub&gt;2&lt;/sub&gt;]. Driven by the urgent need for effective carbon capture technologies to c

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7

Hekmatshoar, R., M. M. Heravi, B. Baghernejad, and K. Asadolah. "MICROWAVE-ASSISTED N-ALKYLATION OF POTASSIUM PHTHALIMIDE AND POTASSIUM SUCCINIMIDE ONTO SILICA GEL IN DRY MEDIA." Phosphorus, Sulfur, and Silicon and the Related Elements 179, no. 8 (2004): 1611–14. http://dx.doi.org/10.1080/10426500490466157.

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8

Kiyani, Hamzeh, and Maryam Bamdad. "One-Pot and Efficient Synthesis of 5-Aminopyrazole-4-carbonitriles Catalyzed by Potassium Phthalimide." HETEROCYCLES 94, no. 2 (2017): 276. http://dx.doi.org/10.3987/com-16-13623.

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9

Dekamin, Mohammad G., and Zahra Karimi. "Activation of trimethylsilyl cyanide by potassium phthalimide for facile synthesis of TMS-protected cyanohydrins." Journal of Organometallic Chemistry 694, no. 12 (2009): 1789–94. http://dx.doi.org/10.1016/j.jorganchem.2009.01.058.

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10

Zhang, Shuai, Yu-Nong Li, Ya-Wei Zhang, et al. "Equimolar Carbon Absorption by Potassium Phthalimide and In Situ Catalytic Conversion Under Mild Conditions." ChemSusChem 7, no. 5 (2014): 1484–89. http://dx.doi.org/10.1002/cssc.201400133.

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11

S., K. Sahu, K. Mishra S., P. Mahapatra S., Bhatta D., and S. Panda C. "Synthesis and hypoglycemic activities of 3-(phthalimidomethyl)-4-substituted-cinnamoyl salicylanilides." Journal of Indian Chemical Society Vol. 81, Mar 2004 (2004): 258–60. https://doi.org/10.5281/zenodo.5830629.

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University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bhubaneswar-751 004, India <em>E-mail</em> : headchemuu09@sify.com         <em> Fax</em>: 91-0674-2581850 Department of Chemistry, Berhampur University, Berhampur-760 007, India <em>Manuscript received 9 December 2002, revised 4 July 2003, accepted 22 August 2003</em> 3-Phthalimidomethylsalicylic acid (2) was prepared by refluxing <em>N</em>-hydroxymethyl phthalimide (1) with salicylic acid. The corresponding acid chloride (3) was condensed with 4-aminoacetophenone in anhydrous potassium ca

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12

Etivand, Nasser, Jabbar Khalafy, and Mohammad G. Dekamin. "Fast and Efficient Green Procedure for the Synthesis of Benzo[5,6]chromene Derivatives and Their Sulfur Analogues in Water by Organocatalyst Potassium Phthalimide-N-oxyl." Synthesis 52, no. 11 (2020): 1707–18. http://dx.doi.org/10.1055/s-0037-1610755.

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A simple, clean, straightforward, and environmentally benign one-pot, three-component reaction of various arylglyoxal monohydrates, β-naphthol, and barbituric acid [pyrimidine-2,4,6(1H,3H,5H)-trione] or thiobarbituric acid in the presence of catalytic amounts potassium phthalimide-N-oxyl (PPINO), as a mild and efficient organocatalyst in aqueous media under reflux conditions is reported. This transformation produced the novel diverse-substituted 12-benzoyl-8,12-dihydro-9H-benzo[5,6]chromeno[2,3-d]pyrimidine-9,11(10H)-diones and their sulfur analogues in 82–93% yield via filtration and without

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13

S., K. Sahu, K. Mishra S., Mandal S., Choudhury P., Sutradhar S., and K. Misro P. "Synthesis and biological evaluation of 3-(phthalimidoethyl)-4-substituted cinnamoyl substituted benzanilides." Journal of Indian Chemical Society Vol. 83, Aug 2006 (2006): 832–34. https://doi.org/10.5281/zenodo.5827824.

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university Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bhubaneswar-751 004, Orissa. India <em>E-mail</em> : tuku_kh@yahoo.com Fax : 91-0674-2581850 Department of Chemistry. Berhampur University, Berhampur-760 007, Orissa, India <em>Manuscript received 6 December 2004, revised 14 November 2005, accepted 10 May 2006</em> 3-Phthalimidoethyl substituted benzoic acids (2) were prepared by refluxing <em>N</em>-hydroxyethyl phthalimide (1) with substituted benzoic acids.The corresponding acid chlorides(3)were condensed with 4 aminoacetophenone in anhydrous potassium carbonate

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14

Dekamin, Mohammad G., Shahrzad Javanshir, M. Reza Naimi-Jamal, Rahim Hekmatshoar, and Javad Mokhtari. "Potassium phthalimide-N-oxyl: An efficient catalyst for cyanosilylation of carbonyl compounds under mild conditions." Journal of Molecular Catalysis A: Chemical 283, no. 1-2 (2008): 29–32. http://dx.doi.org/10.1016/j.molcata.2007.12.007.

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15

Kiyani, H., and M. D. Daroonkala. "A cost-effective and green aqueous synthesis of 3-substituted coumarins catalyzed by potassium phthalimide." Bulletin of the Chemical Society of Ethiopia 29, no. 3 (2015): 449. http://dx.doi.org/10.4314/bcse.v29i3.13.

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16

Yu, Xiaomeng, and Zhongqiang Zhou. "Potassium phthalimide catalyzed efficient synthesis of 2-Amino-3-phenylsulfonyl-4H-chromenes under Solvent-Free Conditions." Phosphorus, Sulfur, and Silicon and the Related Elements 193, no. 6 (2018): 387–93. http://dx.doi.org/10.1080/10426507.2018.1424161.

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17

S., K. Sahu, Afzal Azam Md., Benerjee M., et al. "Synthesis and biological evaluation of 3-(phthalimidomethyl)-4- (5-substituted isoxazoline and pyrazoline) substituted benzanilides." Journal of Indian Chemical Society Vol. 84, Oct 2007 (2007): 1011–15. https://doi.org/10.5281/zenodo.5827044.

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University Department of Pharmaceutical Sciences, Utkal University, Vani Vihar, Bhubaneswar-75 I 005, Orissa, India <em>E-mail</em>: tutu_kh@yahoo.com Department of Pharmaceutical Chemistry, 1. S. S. College of Pharmacy, Ootacamund-643 00 I, Tamilnadu, India Department of Chemistry, Berhampur University, Berhampur-760 00 I, Orissa, India <em>Manuscript received 4 May 2006, revised 24 May 2007, accepted 20 July 2007</em> 3-Phthalimidomethylbcnzoic acids 2 were prepared by treating <em>N</em>-hydroxymethylphthalimidc 1 with substituted benzoic acids. The corresponding acid chlorides 3 were

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18

Moghaddam, Firouz, Mohammad Dekamin, and Gholam Koozehgari. "A Simple and Efficient Method for Synthesis of Isocyanurates Catalyzed by Potassium Phthalimide Under Solvent-Free Conditions." Letters in Organic Chemistry 2, no. 8 (2005): 734–38. http://dx.doi.org/10.2174/157017805774717508.

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19

Böhm, Stanislav, Renata Prantová, David Šaman, Petr Trška, and Josef Kuthan. "Reaction of some nucleophiles with 2,6-di-tert-butylpyrylium perchlorate." Collection of Czechoslovak Chemical Communications 52, no. 5 (1987): 1305–14. http://dx.doi.org/10.1135/cccc19871305.

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The title compound IV reacted with sodium borohydride to give the 4H-pyran VIIa and the dienone VIIIa whereas its reaction with sodium cyanide afforded exclusively the dienone VIIIb. Reaction of the salt IV with tert-butylmagnesium chloride or bromide gave a mixture of the 4H-pyran VIIa and the corresponding 4-tert-butyl derivative V. Upon treatment with hydrogen sulfide and hydrogen chloride, this mixture afforded 2,4,6-tri-tert-butyl-4H-thiopyran XI whereas aromatization with chloranil and subsequent reaction with ammonium acetate resulted in 2,4,6-tri-tert-butylpyridine (X). Analogously, th

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20

S., K. Sahu, Afzal Azam Md., Banerjee M., Choudhury P., Sutradhar S., and K. Misro P. "Synthesis and biological evaluation of 3-(phthalimidoethyl)-4-(5-substituted isoxazoline and pyrazoline) substituted benzanilides." Journal of Indian Chemical Society Vol. 86, May 2009 (2009): 498–503. https://doi.org/10.5281/zenodo.5810178.

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University Department of Pharmaceutical Sciences, Utkal University, Bhubaneswar-751 005, Orissa, India J. S. S. College of Pharmacy, Ootacamund-643 001, Tamilnadu, India Department of Chemistry, Berhampur University, Berhampur-760 007. Orissa, India <em>E-mail</em> : tutu_ kh@yahoo. com <em>Manuscript received 16 March 2008, revised 15 October 2008, accepted 11 February 2009</em> 3-Phthalimidoethyl benzoic acids 2a-g were prepared by treating <em>N</em>-hydroxy-ethylphthalimide 1 with substituted benzoic acids. The corresponding acid chlorides 3a-g were condensed with 4-aminoacetophenone in th

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21

Alhaji, N. M. I., A. M. Uduman Mohideen, and K. Kalaimathi. "Mechanism of Oxidation of (p-Substituted Phenylthio)acetic Acids withN-Bromophthalimide." E-Journal of Chemistry 8, no. 1 (2011): 1–8. http://dx.doi.org/10.1155/2011/560357.

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The kinetics of oxidation of (phenylthio)acetic acid (PTAA) byN-Bromophthalimide (NBP) in acetonitrile-water solvent mixture at 298 K in the presence of perchloric acid has been followed potentiometrically. The reaction is first-order each in NBP and PTAA and inverse fractional-order in H+. Also, it has been found that the reaction rate is not affected by changes in ionic strength of the reaction medium or by the addition of chemicals such as phthalimide, acrylonitrile and potassium bromide. However, an increase in the water content of the solvent mixture causes an increase in the rate of reac

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22

Hammond Quarcoo, Fiona, Juliette C. N. Fouemina, and Gideon Appiah Kusi. "Polymerization of N-phenylmaleimide Using Different Catalysts." Journal of Chemistry Studies 1, no. 2 (2022): 27–35. http://dx.doi.org/10.32996/jcs.2022.1.2.4.

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The polymerization of N-phenylmaleimide (N-PMI) employing sodium phosphate tribasic as a catalyst has been successfully investigated in this study. The effect of dimethyl sulfoxide (DMSO) solvent on the principal catalyst, sodium phosphate tribasic, was extensively studied. The effects of several catalysts, including tetrabutylammonium acetate (TBAA), 4-dimethylaminopyridine (DMAP), Benzyl triethylammonium chloride (BTEAC), 1,5-diazabicyclo[4.3.0]non-5-ene (DBN), 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), 1,4-diazabicyclo[2.2.2]octane (DABCO), 1-Methylimidazole (1MA) and potassium phthalimide s

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23

Kiyani, Hamzeh, and Fatemeh Ghorbani. "Potassium phthalimide as efficient basic organocatalyst for the synthesis of 3,4-disubstituted isoxazol-5(4H)-ones in aqueous medium." Journal of Saudi Chemical Society 21 (January 2017): S112—S119. http://dx.doi.org/10.1016/j.jscs.2013.11.002.

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24

Kiyani, Hamzeh, and Fatemeh Ghorbani. "Potassium phthalimide promoted green multicomponent tandem synthesis of 2-amino-4H-chromenes and 6-amino-4H-pyran-3-carboxylates." Journal of Saudi Chemical Society 18, no. 5 (2014): 689–701. http://dx.doi.org/10.1016/j.jscs.2014.02.004.

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25

Shi, Jinsong, Hongmin Cui, Jianguo Xu, Nanfu Yan, Yuewei Liu, and Shaowei Zhang. "One-step synthesis of highly porous nitrogen doped carbon from the direct pyrolysis of potassium phthalimide for CO2 adsorption." Journal of CO2 Utilization 39 (July 2020): 101164. http://dx.doi.org/10.1016/j.jcou.2020.101164.

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26

Kiyani, Hamzeh, and Fatemeh Ghorbani. "Potassium phthalimide: an efficient and simple organocatalyst for the one-pot synthesis of dihydropyrano[3,2-c]chromenes in aqueous media." Research on Chemical Intermediates 41, no. 6 (2013): 4031–46. http://dx.doi.org/10.1007/s11164-013-1508-2.

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27

Odiya, S. P., S. P. Das, J. J. Boruah, and D. P. Rajani. "Synthesis of New Cyclohexenone Derivatives Using Potassium Phthalimide as a Green Organocatalyst. One-Pot Microwave-Assisted Synthesis and Antimicrobial Evaluation." Russian Journal of Organic Chemistry 59, no. 1 (2023): 117–32. http://dx.doi.org/10.1134/s107042802301013x.

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28

White, Robert L., Kevin C. Smith, and Alphonse C. DeMarco. "Biosynthesis of 5-hydroxy-4-oxo-L-norvaline in Streptomyces akiyoshiensis." Canadian Journal of Chemistry 72, no. 7 (1994): 1645–55. http://dx.doi.org/10.1139/v94-207.

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The biosynthesis of 5-hydroxy-4-oxo-L-norvaline (HON) in Streptomyces akiyoshiensis has been investigated using 13C-labelled substrates. Incorporations of 13C label from sodium [1-13C]-, [2-13C]-, and [1,2-13C2]acetate indicated that HON was formed from a four-carbon compound derived from the citric acid cycle and the methyl carbon of acetate. Feeding experiments using DL-[4-13C]- and DL-[2-13C,15N]aspartate demonstrated that aspartate served as the four-carbon precursor to HON. Both enantiomers of aspartate were metabolized by S. akiyoshiensis, but the D isomer was consumed at a slower rate.

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29

Kiyani, Hamzeh, and Maryam Ghiasi. "Solvent-free efficient one-pot synthesis of Biginelli and Hantzsch compounds catalyzed by potassium phthalimide as a green and reusable organocatalyst." Research on Chemical Intermediates 41, no. 8 (2014): 5177–203. http://dx.doi.org/10.1007/s11164-014-1621-x.

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30

Barrett, Anthony G. M., D. Christopher Braddock, Rachel A. James, and Panayiotis A. Procopiou. "Nucleophilic substitution of (alkoxymethylene)dimethylammonium chloride with potassium phthalimide; a convenient procedure for the synthesis of imides with inversion of configuration." Chemical Communications, no. 5 (1997): 433–34. http://dx.doi.org/10.1039/a607482k.

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31

Hussain, Talib, Syed Mohd Danish Rizvi, Gehad M. Subaiea, Abulrahman Sattam Alanazi, and Afrasim Moin. "Designing dual inhibitors for the treatment of Alzheimer’s disease as well as Type 2 diabetes mellitus via pharmacoinformatics approach: A step towards better medication for diabetes-associated neurological disorder." Tropical Journal of Pharmaceutical Research 19, no. 6 (2020): 1233–42. http://dx.doi.org/10.4314/tjpr.v19i6.18.

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Purpose: To design dual inhibitors against Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM) via pharmacoinformatics approach.Methods: Dual Drug Candidates (DDC) were designed and explored for their molecular interaction with several AD and T2DM targets. Pterostilbene, a natural anti-T2DM compound was coupled with different cholinesterase inhibitors to design DDC. Orisis Datawarrior online property calculator tools, Autock 4.2 and Hex 5.1 were used to investigate the potency of all DDC relative to positive controls.Results: The study found that DDC2 (pterostilbene - methylene linker

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32

Ghorbani, Fatemeh, and Hamzeh Kiyani. "Facile Three-Component Synthesis of 7-Arylbenzo[f]Chromeno[4,3- b]Chromen-6(7H)-Ones Catalyzed by Potassium Phthalimide in Aqueous Media." Jordan Journal of Chemistry 9, no. 1 (2014): 1–6. http://dx.doi.org/10.12816/0026390.

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33

BARRETT, A. G. M., D. C. BRADDOCK, R. A. JAMES, and P. A. PROCOPIOU. "ChemInform Abstract: Nucleophilic Substitution of (Alkoxymethylene)dimethylammonium Chloride with Potassium Phthalimide; a Convenient Procedure for the Synthesis of Imides with Inversion of Configuration." ChemInform 28, no. 27 (2010): no. http://dx.doi.org/10.1002/chin.199727132.

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34

Kiyani, Hamzeh, and Maryam Bamdad. "Correction to “One-Pot and Efficient Synthesis of 5-Aminopyrazole-4-carbonitriles Catalyzed by Potassium Phthalimide”: HETEROCYCLES, 2017, 94, 276, DOI: 10.3987/COM-16-13623." HETEROCYCLES 98, no. 4 (2019): 618. http://dx.doi.org/10.3987/correction-com-16-13623.

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35

Etivand, Nasser, Jabbar Khalafy, and Mohammad G. Dekamin. "Fast and Efficient Green Procedure for the Synthesis of Benzo[5,6]chromene Derivatives and Their Sulfur Analogues in Water by Organocatalyst Potassium Phthalimide-N-oxyl." Synthesis 52, no. 11 (2020): e2-e2. http://dx.doi.org/10.1055/s-0039-1690093.

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36

Dekamin, Mohammad G., Mohammad Eslami, and Ali Maleki. "Potassium phthalimide-N-oxyl: a novel, efficient, and simple organocatalyst for the one-pot three-component synthesis of various 2-amino-4H-chromene derivatives in water." Tetrahedron 69, no. 3 (2013): 1074–85. http://dx.doi.org/10.1016/j.tet.2012.11.068.

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37

D. Patel, Hitesh, Rajesh H. Vekariya, Kinjal D. Patel, and Neelam P. Prajapati. "Potassium Phthalimide (PPI): an Efficient and Green Organocatalyst for the One-pot Synthesis of 6-amino-1,4-dihydropyrano[2,3-c]-pyrazole-5-carbonitrile Derivatives under Microwave Irradiation." Current Microwave Chemistry 03, no. 999 (2016): 1. http://dx.doi.org/10.2174/2213335603666160304192946.

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38

Vekariya, Rajesh H., Kinjal D. Patel, Neelam P. Prajapati, and Hitesh D. Patel. "Potassium Phthalimide (PPI): An Efficient and Green Organocatalyst for the One-pot Synthesis of 6-amino-1,4-dihydropyrano[2,3-c]-pyrazole-5- carbonitrile Derivatives under Microwave Irradiation." Current Microwave Chemistry 4, no. 2 (2017): 122–27. http://dx.doi.org/10.2174/2213335603666160408162601.

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39

Dekamin, Mohammad G., Mohammad Eslami, and Ali Maleki. "ChemInform Abstract: Potassium Phthalimide-N-oxyl: A Novel, Efficient, and Simple Organocatalyst for the One-Pot Three-Component Synthesis of Various 2-Amino-4-chromene Derivatives in Water." ChemInform 44, no. 22 (2013): no. http://dx.doi.org/10.1002/chin.201322145.

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40

Kiyani, Hamzeh, and Maryam Ghiasi. "Potassium phthalimide: An efficient and green organocatalyst for the synthesis of 4-aryl-7-(arylmethylene)-3,4,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-2(5H)-ones/thiones under solvent-free conditions." Chinese Chemical Letters 25, no. 2 (2014): 313–16. http://dx.doi.org/10.1016/j.cclet.2013.11.042.

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41

Kiyani, Hamzeh, and Maryam Ghiasi. "ChemInform Abstract: Potassium Phthalimide: An Efficient and Green Organocatalyst for the Synthesis of 4-Aryl-7-(arylmethylene)-3,4,6,7-tetrahydro-1H-cyclopenta [d]pyrimidin-2(5H)-ones/thiones under Solvent-Free Conditions." ChemInform 45, no. 28 (2014): no. http://dx.doi.org/10.1002/chin.201428173.

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42

Spassova, Maria, Hana Dvořáková, Antonín Holý, Miloš Buděšínský, and Milena Masojídková. "Synthesis of N-(3-Azido-2-hydroxypropyl), N-(3-Phthalimido-2-hydroxypropyl) and N-(3-Amino-2-hydroxypropyl) Derivatives of Heterocyclic Bases." Collection of Czechoslovak Chemical Communications 59, no. 5 (1994): 1153–74. http://dx.doi.org/10.1135/cccc19941153.

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Alkylation of heterocyclic bases with azidomethyloxirane (I) under basic catalysis with potassium or cesium carbonate afforded N-(3-azido-2-hydroxypropyl) derivatives II. Hydrogenation of these compounds over palladium on carbon gave the corresponding 3-amino-2-hydroxypropyl derivatives III. The same compounds III were prepared by alkylation of heterocyclic bases with phthalimidomethyloxirane (VII) in the presence of cesium carbonate and subsequent reaction of the formed N-(3-phthalimido-2-hydroxypropyl) derivatives VIII with hydrazine. The phthalimido derivatives VIII are easily hydrolyzed al

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43

Silva, José Guedes da, André de Lima Aires, Rebeca Xavier da Cunha, et al. "Anti-Hyperuricemic, Anti-Arthritic, Hemolytic Activity and Therapeutic Safety of Glycoconjugated Triazole-Phthalimides." Biomedicines 11, no. 9 (2023): 2537. http://dx.doi.org/10.3390/biomedicines11092537.

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Hyperuricemia, the metabolic alteration that leads to gout or gouty arthritis, is increasing worldwide. Glycoconjugated triazole-phthalimides show potent anti-inflammatory activity. The aim of this study was to evaluate the anti-hyperuricemia effect of glycoconjugated triazole-phthalimides. To develop hyperuricemia, groups of mice received orally potassium oxonate (250 mg/kg) for 7 days, and F2, F3 and F4 glycoconjugated triazole-phthalimides (20 mg/kg), allopurinol (300 mg/kg), and 1% carboxymethylcellulose; indomethacin (2 and 4 mg/kg) was the positive control for anti-arthritic effect. Geno

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44

Zaidi, Saiyid Aftab A., Maimoona Jaria, and Zafar A. Siddiqi. "Syntheses and Physico-Chemical Studies of Potassium Hydrotris and Tetrakis (Phthalimidyl) borates and Their Complexes with First Row Transition Metal Ions." Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 16, no. 8 (1986): 1067–87. http://dx.doi.org/10.1080/00945718608071382.

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45

Khengar, Urvi J., Dharti R. Bhandari, Rajesh H. Vekariya, and Jinal A. Gajjar. "An overall development on catalytic applications of potassium phthalimide (PPI) and potassium phthalimide -N- oxyl (POPINO) in organic synthesis." Synthetic Communications, April 25, 2024, 1–18. http://dx.doi.org/10.1080/00397911.2024.2342316.

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46

Alali, Ibtisam, and Robert Mokaya. "Direct synthesis of organic salt-derived porous carbons for enhanced CO₂ and methane storage." Journal of Materials Chemistry A, 2023. http://dx.doi.org/10.1039/d3ta00044c.

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Carbonisation of potassium phthalimide (PPI) generates microporous carbons with exceptional gas uptake at 25 °C; 5.2 mmol per g CO2 @ 1 bar, and methane storage of 338 cm3 (STP) cm−3 at 100 bar with 100–5 bar working capacity of 249 cm3 (STP) cm−3.

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47

Verbeet, Wessel, Yurii Husiev, and Sylvestre Bonnet. "Simple and Efficient Method for Mono‐ and Di‐Amination of Polypyridine N‐Oxides." European Journal of Organic Chemistry, February 28, 2024. http://dx.doi.org/10.1002/ejoc.202400054.

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Herein we report a simple synthetic route towards both known and novel aminated polypyridyl ligands. The use of tosyl chloride in combination with potassium phthalimide followed by hydrolysis allows for chemo‐selective ortho‐amination of (poly)pyridyl mono‐ and di‐N‐oxides with good to excellent yield. The reactions are scalable and reproducible while using inexpensive, commercially available reagents.

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48

feng, shubo, Guiqiang Han, Xianghao Meng, and Weijie Shi. "Synthesis of Fatty Acid Methyl Ester Catalyzed by Potassium Phthalimide." SSRN Electronic Journal, 2021. http://dx.doi.org/10.2139/ssrn.3975666.

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Kiyani, Hamzeh, and Fatemeh Ghorbani. "Potassium phthalimide-catalysed one-pot multi-component reaction for efficient synthesis of amino-benzochromenes in aqueous media." Chemical Papers 68, no. 8 (2014). http://dx.doi.org/10.2478/s11696-014-0554-6.

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Abstract2-Amino-4-aryl-4H-benzo[h]chromenes and 3-amino-1-aryl-1H-benzo[f]chromenes were prepared by treating cyano-methylene compounds (malononitrile or ethyl cyanoacetate), substituted aromatic aldehydes, and naphtholic compounds in the presence of potassium phthalimide as a green, mild, efficient, and commercially available organocatalyst in aqueous media. The procedure was readily conducted and affords remarkable advantages such as safety, short reaction times, environmentally benign milder reaction conditions, no organic solvent required, and high yields.

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Hekmatshoar, R., M. M. Heravi, B. Baghernejad, and K. Asadolah. "Microwave-Assisted N-Alkylation of Potassium Phthalimide and Potassium Succinimide onto Silica Gel in Dry Media." ChemInform 35, no. 49 (2004). http://dx.doi.org/10.1002/chin.200449049.

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