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Journal articles on the topic 'Potential flow. eng'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Honório, Michelle da Silva, Roberta Vieira Nunes Pinheiro, Isabella Almeida Costa, and Paulo Sérgio Scalize. "Comparison of two methods for determining Q95 reference flow in the mouth of the surface catchment basin of the Meia Ponte river, state of Goiás, Brazil." Open Engineering 10, no. 1 (2020): 469–76. http://dx.doi.org/10.1515/eng-2020-0053.

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AbstractThe preferred data for analyzing water availability are those of historical flow series of the sources of interest; however, most Brazilian watersheds do not have sufficient fluviometric monitoring. Such cases require techniques for transposing data from one region to another, otherwise known as ‘flow regionalization’. The present work aimed to compare the method proposed by Secretaria de Meio Ambiente e Desenvolvimento Sustentável (SEMAD) of the state of Goiás with the traditional method of regionalization for determining reference flow at the mouth of the surface catchment basin of t

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Badano, Nicolás, Rodolfo Espina Valdés, and Eduardo Álvarez Álvarez. "Tidal current energy potential of Nalón river estuary assessment using a high precision flow model." Open Engineering 8, no. 1 (2018): 118–23. http://dx.doi.org/10.1515/eng-2018-0015.

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Abstract Obtaining energy from tide currents in onshore locations is of great interest due to the proximity to the points of consumption. This opens the door to the feasibility of new installations based on hydrokinetic microturbines even in zones of moderate speed. In this context, the accuracy of energy predictions based on hydrodynamic models is of paramount importance. This research presents a high precision methodology based on a multidimensional hydrodynamic model that is used to study the energetic potential in estuaries. Moreover, it is able to estimate the flow variations caused by mi

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Lai, W. Michael, Van C. Mow, Daniel D. Sun, and Gerard A. Ateshian. "On the Electric Potentials Inside a Charged Soft Hydrated Biological Tissue: Streaming Potential Versus Diffusion Potential." Journal of Biomechanical Engineering 122, no. 4 (2000): 336–46. http://dx.doi.org/10.1115/1.1286316.

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The main objective of this study is to determine the nature of electric fields inside articular cartilage while accounting for the effects of both streaming potential and diffusion potential. Specifically, we solve two tissue mechano-electrochemical problems using the triphasic theories developed by Lai et al. (1991, ASME J. Biomech Eng., 113, pp. 245–258) and Gu et al. (1998, ASME J. Biomech. Eng., 120, pp. 169–180) (1) the steady one-dimensional permeation problem; and (2) the transient one-dimensional ramped-displacement, confined-compression, stress-relaxation problem (both in an open circ

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Al-Mistarehi, Bara’ W., Ahmad H. Alomari, and Mohamad S. Al Zoubi. "Investigation of saturation flow rate using video camera at signalized intersections in Jordan." Open Engineering 11, no. 1 (2020): 216–26. http://dx.doi.org/10.1515/eng-2021-0021.

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AbstractThis study aimed to investigate a potential list of variables that may have an impact on the saturation flow rate (SFR) associated with different turning movements at signalized intersections in Jordan. Direct visits to locations were conducted, and a video camera was used. Highway capacity manual standard procedure was followed to collect the necessary traffic data. Multiple linear regression was performed to classify the factors that impact the SFR and to find the optimal model to foretell the SFR. Results showed that turning radius, presence of camera enforcement, and the speed limi

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Strohmandl, Jan, and Zdeněk Čujan. "Risk Minimisation in Integrated Supply Chains." Open Engineering 9, no. 1 (2019): 593–99. http://dx.doi.org/10.1515/eng-2019-0082.

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AbstractIntegrated supply chains, due to their complexity, are vulnerable in relation to various types of risks, especially in the present turbulent market environment, characterised by increased demand for effectiveness of the individual logistic activities, extended customer service and decreased cost. The supply chain risks are represented by any threatening event that may unexpectedly disrupt or restrict material flow, or directly stop the scheduled logistic or manufacturing activities. Supply chain risk management includes risk identification, analysis and implementation of measures again

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Chomiuk, Bartłomiej, and Janusz Skrzypacz. "Comparison of energy parameters of a centrifugal pump with a multi-piped impeller in cooperation either with an annular channel and a spiral channel." Open Engineering 8, no. 1 (2018): 513–22. http://dx.doi.org/10.1515/eng-2018-0063.

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Abstract The article presents results of numerical analyzes, which raise a subject of influence of the cooperation the multi-piped impeller with a rationalized flow geometry of annular casing and volute casing for liquid flow through centrifugal pump and their operating parameters in the extremely low specific speed nq<10. The multi-piped impeller (patented by authors) is a major alternative to classic vane impellers. The stator type is responsible for the conversion of the kinetic energy of the liquid by the impeller outlet into potential energy, which determines the overall efficiency of

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Scalize, Paulo Sergio, Samara Silva Soares, Andreia Cristina Fonseca Alves, et al. "Use of condensed water from air conditioning systems." Open Engineering 8, no. 1 (2018): 284–92. http://dx.doi.org/10.1515/eng-2018-0031.

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Abstract Facing the growing demand for water, discussions on environmental sustainability and conservation of this resource have become increasingly important. Among the possibilities for water conservation, air conditioning systems have potential applicability because, during their operation, water is generated via the condensation of air humidity, which is normally discarded. Thus, the objective of this work was to evaluate the water released by air conditioning equipment (condensed water) installed in the Laboratory of Water Analysis (LAnA) qualitatively and quantitatively, in order to veri

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8

Elad, D., R. D. Kamm, and A. H. Shapiro. "Mathematical simulation of forced expiration." Journal of Applied Physiology 65, no. 1 (1988): 14–25. http://dx.doi.org/10.1152/jappl.1988.65.1.14.

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Flow limitation during forced expiration is simulated by a mathematical model. This model draws on the pressure-area law obtained in the accompanying paper, and the methods of analysis for one-dimensional flow in collapsible tubes developed by Shapiro (Trans. ASME J. Biomech. Eng. 99: 126-147, 1977). These methods represent an improvement over previous models in that 1) the effects of changing lung volume and of parenchymal-bronchial interdependence are simulated; 2) a more realistic representation of collapsed airways is employed; 3) a solution is obtained mouthward of the flow-limiting site

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9

Mu-Mosley, Hong, Lauren B. Ostermann, Ran Zhao, et al. "Venetoclax Enhances Anti-Leukemia Activity of CD123-Specific BiTE-Secreting T-Cells in AML." Blood 136, Supplement 1 (2020): 12–13. http://dx.doi.org/10.1182/blood-2020-139625.

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Background: CD123 is frequently expressed in hematologic malignancies including AML. CD123 has been a potential immunotherapeutic target in AML due to its association with leukemic stem cells that play an essential role in disease progression and relapse. Our previous study using T-cells secreting CD123/CD3-bispecific T-cell engagers (BiTEs) (CD123-ENG T-cells) has shown activity in preclinical studies, recognizing and killing acute myeloid leukemia (AML) blasts in vitro and in vivo. CD123-ENG T-cells secrete bispecific molecules that recognize CD3 (T-cells) and CD123 (AML blasts), and are abl

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10

Ehrich, F. F., Z. S. Spakovszky, M. Martinez-Sanchez, et al. "Unsteady Flow and Whirl-Inducing Forces in Axial-Flow Compressors: Part II—Analysis." Journal of Turbomachinery 123, no. 3 (2000): 446–52. http://dx.doi.org/10.1115/1.1370165.

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An experimental and theoretical investigation was conducted to evaluate the effects seen in axial-flow compressors when the centerline of the rotor becomes displaced from the centerline of the static structure of the engine, thus creating circumferentially nonuniform rotor-tip clearances. This displacement produces unsteady flow and creates a system of destabilizing forces, which contribute significantly to rotor whirl instability in turbomachinery. These forces were first identified by Thomas (1958. Bull. AIM, 71, No. 11/12, pp. 1039–1063.) for turbines and by Alford (1965. J. Eng. Power, Oct

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Mu, Hong, Huaxian Ma, Abishek Vaidya, et al. "IL15 Expressing CD123-Targeted Engager T-Cell Therapy for Adult Acute Myeloid Leukemia." Blood 132, Supplement 1 (2018): 2724. http://dx.doi.org/10.1182/blood-2018-99-116811.

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Abstract Background: CD123 is a potential immunotherapeutic target in AML due to its overexpression on leukemic stem cells that play an essential role in disease progression and relapse. Our previous study using T cells secreting CD123/CD3 bispecific engager molecules (CD123-ENG T cells) showed promising results in pediatric AML. Interleukin-15 (IL15) has emerged as a candidate immunomodulator as it enhances the cytolytic activity of CD8+ T-cells and induces long-lasting memory T cells. To improve the efficacy and persistence of CD123-ENG T-cells we developed IL-15 expressing CD123-ENG T cells

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McBain, Geordie Drummond. "Three ways to compute multiport inertance." ANZIAM Journal 60 (August 26, 2019): C140—C155. http://dx.doi.org/10.21914/anziamj.v60i0.14058.

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The immediate impulse-response of a confined incompressible fluid is characterized by inertance. For a vessel with one inlet and outlet, this is a single quantity; for multiple ports the generalization is a singular reciprocal inertance matrix which acts on the port-impulses to give the corresponding inflows. The reciprocal inertance coefficients are defined by the boundary fluxes of potential flows. Green's identity converts these coefficients to domain integrals of kinetic energy. For a system discretized with finite elements, a third method is proposed for computing reciprocal inertance coe

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Sangiolo, Dario, Noela Jordaney, Giulia Mesiano, et al. "Lentiviral Engineered T Regulatory Cells Effectively Inhibit Lymphocytes Alloreactivity across Major HLA Barriers." Blood 112, no. 11 (2008): 3515. http://dx.doi.org/10.1182/blood.v112.11.3515.3515.

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Abstract Adoptive immunotherapy strategies enrolling T regulatory cells (Tregs) might have a great potential in modulating donor T cells alloreactivity after Hematopoetic Cell Transplant (HCT). In murine models of HCT Tregs were shown to promote engraftment and contribute controlling graft versus host disease (GVHD) while still not conclusive data are available on humans. Ex-vivo engineering conventional CD4+ T cells to over-express the transcription factor FOXP3 is an intriguing approach to overcome the main difficulty of obtaining large amount of Tregs for experimental studies. Reports of re

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Vaidya, Abishek, Erin E. Doherty, Xiya Wu, Challice L. Bonifant, Stephen Gottschalk, and Mireya Paulina Velasquez. "Inducible MyD88 Signaling Enhances the Anti-AML Activity of BiTE-Secreting ENG T-Cells." Blood 134, Supplement_1 (2019): 4441. http://dx.doi.org/10.1182/blood-2019-125395.

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Background: Pediatric and adult acute myeloid Leukemia (AML) is a disease with poor prognosis due to its high relapse rate and treatment related mortality. Adoptive immunotherapy has the potential to improve outcomes and CD123 present a promising immunotherapy target for AML. CD123-specific engager (ENG) T-cells are cells genetically modified to secrete bispecific T-cell engagers (BiTEs) that recognize CD3+ on T-cells and CD123+ on AML. We had previously shown that inclusion of an inducible MyD88/CD40 costimulatory molecule, which is activated by a chemical inducer of dimerization (CID), impro

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15

Xu, Zhanxian. "A Kind of Potential Practical Sensors of Metamaterial in Electromagnetic Flaw Nondestructive Testing." Engineering 03, no. 07 (2011): 750–54. http://dx.doi.org/10.4236/eng.2011.37090.

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16

Railsback, Steven F., Bret C. Harvey, Sarah J. Kupferberg, Margaret M. Lang, Scott McBain, and Hart H. Welsh. "Modeling potential river management conflicts between frogs and salmonids." Canadian Journal of Fisheries and Aquatic Sciences 73, no. 5 (2016): 773–84. http://dx.doi.org/10.1139/cjfas-2015-0267.

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Management of regulated rivers for yellow-legged frogs (Rana boylii) and salmonids exemplifies potential conflicts among species adapted to different parts of the natural flow and temperature regimes. Yellow-legged frogs oviposit in rivers in spring and depend on declining flows and warming temperatures for egg and tadpole survival and growth, whereas salmonid management can include high spring flows and low-temperature reservoir releases. We built a model of how flow and temperature affect frog breeding success. Its mechanisms include adults selecting oviposition sites to balance risks of egg

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17

Weiner, Benjamin J., and J. A. Sellwood. "Properties of the Galactic Bar from Hydrodynamical Simulations." Symposium - International Astronomical Union 169 (1996): 145–46. http://dx.doi.org/10.1017/s0074180900229628.

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It is well known that the existence of H I and CO gas at “forbidden” velocities in longitude-velocity (l–V) diagrams of the inner Galaxy (e.g. Liszt & Burton 1980, Liszt 1992) is inconsistent with circular motion in an axisymmetric potential. Gas flow in a barred potential could be consistent with the observations, however. We have compared the observations to 2-D hydrodynamical simulations of gas flows in a family of barred potentials. The gas flow pattern is very sensitive to the assumed potential, and the l–V distribution of cool gas in the inner Galaxy places strong constraints on seve

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18

Sanvitale, Nicoletta, Elisabeth Bowman, and Miguel Angel Cabrera. "Experimental Investigation on the Impact Dynamics of Saturated Granular Flows on Rigid Barriers." Environmental and Engineering Geoscience 27, no. 1 (2021): 127–38. http://dx.doi.org/10.2113/eeg-d-20-00033.

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ABSTRACT Debris flows involve the high-speed downslope motion of rocks, soil, and water. Their high flow velocity and high potential for impact loading make them one of the most hazardous types of gravitational mass flows. This study focused on the roles of particle size grading and degree of fluid saturation on impact behavior of fluid-saturated granular flows on a model rigid barrier in a small-scale flume. The use of a transparent debris-flow model and plane laser-induced fluorescence allowed the motion of particles and fluid within the medium to be examined and tracked using image processi

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19

Newmiller, Jeanette, Wesley Walker, William E. Fleenor, and Nicholas Pinter. "Case Study: Reconstructing the 2015 Dulcepamba River Flood Disaster." Environmental and Engineering Geoscience 26, no. 4 (2020): 393–404. http://dx.doi.org/10.2113/eeg-2337.

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ABSTRACT In March 2015, the village of San Pablo de Amalí on the Dulcepamba River in Ecuador was hit by a flood that killed three residents, destroyed five homes, and eroded several hectares of farmland. Residents asserted that the recent construction of a run-of-the-river hydroelectric facility built in the river channel directed flood flows toward the village, causing the associated damage and fatalities. We conducted a forensic hydrologic and hydraulic analysis of the catchment to assess potential causal mechanisms affecting flooding, including the construction of the hydroelectric facility

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McGuire, Luke A., Francis K. Rengers, Nina Oakley, et al. "Time Since Burning and Rainfall Characteristics Impact Post-Fire Debris-Flow Initiation and Magnitude." Environmental and Engineering Geoscience 27, no. 1 (2021): 43–56. http://dx.doi.org/10.2113/eeg-d-20-00029.

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ABSTRACT The extreme heat from wildfire alters soil properties and incinerates vegetation, leading to changes in infiltration capacity, ground cover, soil erodibility, and rainfall interception. These changes promote elevated rates of runoff and sediment transport that increase the likelihood of runoff-generated debris flows. Debris flows are most common in the year immediately following wildfire, but temporal changes in the likelihood and magnitude of debris flows following wildfire are not well constrained. In this study, we combine measurements of soil-hydraulic properties with vegetation s

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Cheng, Long, Salman Ahmed, Hans Liljestrand, et al. "Exploitation Techniques for Data-oriented Attacks with Existing and Potential Defense Approaches." ACM Transactions on Privacy and Security 24, no. 4 (2021): 1–36. http://dx.doi.org/10.1145/3462699.

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Data-oriented attacks manipulate non-control data to alter a program’s benign behavior without violating its control-flow integrity. It has been shown that such attacks can cause significant damage even in the presence of control-flow defense mechanisms. However, these threats have not been adequately addressed. In this survey article, we first map data-oriented exploits, including Data-Oriented Programming (DOP) and Block-Oriented Programming (BOP) attacks, to their assumptions/requirements and attack capabilities. Then, we compare known defenses against these attacks, in terms of approach, d

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Campos, L. M. B. C. "On 36 Forms of the Acoustic Wave Equation in Potential Flows and Inhomogeneous Media." Applied Mechanics Reviews 60, no. 4 (2007): 149–71. http://dx.doi.org/10.1115/1.2750670.

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The starting point in the formulation of most acoustic problems is the acoustic wave equation. Those most widely used, the classical and convected wave equations, have significant restrictions, i.e., apply only to linear, nondissipative sound waves in a steady homogeneous medium at rest or in uniform motion. There are many practical situations violating these severe restrictions. In the present paper 36 distinct forms of the acoustic wave equation are derived (and numbered W1–W36), extending the classical and convected wave equations to include cases of propagation in inhomogeneous and∕or unst

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Nordey, Thibault, Mathieu Léchaudel, and Michel Génard. "The decline in xylem flow to mango fruit at the end of its development is related to the appearance of embolism in the fruit pedicel." Functional Plant Biology 42, no. 7 (2015): 668. http://dx.doi.org/10.1071/fp14306.

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The decline in xylem flow during the late growth stage in most fruits may be due either to a decrease in the water potential gradient between the stem bearing the fruit and the fruit tissues or to a decrease in the hydraulic conductivity of xylem vessels, or both. In this study, we analysed changes in xylem flows to the mango Mangifera indica L. fruit during its development to identify the sources of variation by measuring changes in the water potential gradient and in the hydraulic properties of the fruit pedicel. The variations in xylem and transpiration flows were estimated at several stage

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Aliseda, Alberto, and Theodore J. Heindel. "X-Ray Flow Visualization in Multiphase Flows." Annual Review of Fluid Mechanics 53, no. 1 (2021): 543–67. http://dx.doi.org/10.1146/annurev-fluid-010719-060201.

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The use of X-ray flow visualization has brought a powerful new tool to the study of multiphase flows. Penetrating radiation can probe the spatial concentration of the different phases without the refraction, diffraction, or multiple scattering that usually produce image artifacts or reduce the signal-to-noise ratio below reliable values in optical visualization of multiphase flows; hence, X-ray visualization enables research into the three-dimensional (3D) structure of multiphase flows characterized by complex interfaces. With the commoditization of X-ray laboratory sources and wider access to

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25

Iga, Keita. "Shear instability as a resonance between neutral waves hidden in a shear flow." Journal of Fluid Mechanics 715 (January 9, 2013): 452–76. http://dx.doi.org/10.1017/jfm.2012.529.

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AbstractA concept which explains unstable modes by resonance between two neutral waves is applied to instability in shear flows with non-uniform potential vorticity distribution. In basic flows where shear instability occurs, a pair of neutral waves which should resonate to form an unstable mode does not exist mathematically unless the basic potential vorticity is uniform, owing to the shear of the basic flow. However, if a small window region is made where the potential vorticity of the basic flow is uniform, regular neutral modes can exist. The neutral wave located at the centre of this wind

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Bleker de Oliveira, Mariana, Paola Marino Dantonio, Veruska Lia Fook Alves, et al. "Multiple Myeloma Cancer Stem Cells: Immunophenotypic and Functional Characterization, Gene Expression Profiling and Therapeutic Targets." Blood 128, no. 22 (2016): 4434. http://dx.doi.org/10.1182/blood.v128.22.4434.4434.

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Abstract Background: Despite the increase in patients' survival over the last years, multiple myeloma (MM) remains incurable, being persistence of cancer stem cells (CSCs) a probable cause of drug resistance and disease relapse. It is possible to isolate these cells using surface antigen expression pattern (CD19+/CD34+/CD138-) and the activity of an enzyme from aldehyde dehydrogenase (ALDH) family (Boucher et al., 2012). We believe that using CD19 as potential marker of MM-CSCs makes CAR-T cell therapy against CD19 an option to eradicate residual MM disease. Aims: To isolate and characterize i

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27

VERHOFF, A. "Two-dimensional potential flow solutions with separation." Journal of Fluid Mechanics 657 (July 21, 2010): 238–64. http://dx.doi.org/10.1017/s0022112010001448.

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A procedure for constructing two-dimensional incompressible potential flowfield solutions with separation and a recirculation region is presented. It naturally makes use of complex variable theory and other analysis techniques such as conformal mapping and the generalized Poisson integral formula. Flowfield determination is reduced to solution of a boundary value problem in various simple domains. The entire velocity field is described analytically; stream function and velocity potential contour maps are readily constructed. Example solutions are presented. Solutions for sharp leading edge air

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Keil, Julian, Jana Timm, Iria SanMiguel, Hannah Schulz, Jonas Obleser, and Marc Schönwiesner. "Cortical brain states and corticospinal synchronization influence TMS-evoked motor potentials." Journal of Neurophysiology 111, no. 3 (2014): 513–19. http://dx.doi.org/10.1152/jn.00387.2013.

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Transcranial magnetic stimulation (TMS) influences cortical processes. Recent findings indicate, however, that, in turn, the efficacy of TMS depends on the state of ongoing cortical oscillations. Whereas power and phase of electromyographic (EMG) activity recorded from the hand muscles as well as neural synchrony between cortex and hand muscles are known to influence the effect of TMS, to date, no study has shown an influence of the phase of cortical oscillations during wakefulness. We applied single-pulse TMS over the motor cortex and recorded motor-evoked potentials along with the electroenc

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Noblesse, Francis, Lijue Wang, and Chi Yang. "A Simple Verification Test for Nonlinear Flow Calculations Around a Ship Hull Steadily Advancing in Calm Water." Journal of Ship Research 56, no. 03 (2012): 162–69. http://dx.doi.org/10.5957/jsr.2012.56.3.162.

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Simple analytical relations that can readily be applied to verify a critical aspect of numerical predictions of fully nonlinear free-surface flows around ship hulls steadily advancing in calm water are given. The relations do not involve the flow field equations; that is, they are only based on the boundary conditions at the ship hull surface and at the free surface. These boundary conditions have a predominant influence on free-surface flows around advancing ship hulls. The analytical relations are exact for inviscid flows, and can be applied to numerical methods that solve either the Laplace

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Sturzenegger, Matthieu, Kris Holm, Carie-Ann Lau, and Matthias Jakob. "Debris-Flow and Debris-Flood Susceptibility Mapping for Geohazard Risk Prioritization." Environmental and Engineering Geoscience 27, no. 2 (2021): 179–94. http://dx.doi.org/10.2113/eeg-d-20-00006.

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ABSTRACT Regional-scale assessments for debris-flow and debris-flood propagation and avulsion on fans can be challenging. Geomorphological mapping based on aerial or satellite imagery requires substantial field verification effort. Surface evidence of past events may be obfuscated by development or obscured by repeat erosion or debris inundation, and trenching may be required to record the sedimentary architecture and date past events. This paper evaluates a methodology for debris-flow and debris-flood susceptibility mapping at regional scale based on a combination of digital elevation model (

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Murakami, Shinsuke. "Flow Scenarios and Resource Potentials for End-of-life Electric Appliances." Material Cycles and Waste Management Research 20, no. 5 (2009): 237–44. http://dx.doi.org/10.3985/mcwmr.20.237.

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Findlay, L. M. "Reading and Teaching Troilus Otherwise: St Maure, Chaucer, Henryson." Florilegium 16, no. 1 (1999): 61–75. http://dx.doi.org/10.3138/flor.16.007.

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Medieval studies has it all . At the end of the twentieth century, whatever one wishes to explore, one can find it adumbrated or more plainly available in the middle ages. Nor does one have to listen (as I have done with pleasure and profit over the years) to that committed teacher and scholar, Douglas Wurtele, in order to appreciate this. I was assured of that by Matthew P. MacDiarmid when I was an undergraduate at Aberdeen. When I went to Oxford as a graduate student, the endless potential and compelling actualities of medieval studies were even more palpable than at Aber-deen, especially fo

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Condie, Scott A., and Ross W. Griffiths. "Convection in a rotating cavity: modelling ocean circulation." Journal of Fluid Mechanics 207 (October 1989): 453–74. http://dx.doi.org/10.1017/s002211208900265x.

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Large-scale oceanic flows, ranging from large estuaries to basin-scale abyssal circulation, can be driven by imposed lateral density gradients and are significantly influenced by the Earth's rotation. Some essential features of such flows have been incorporated into a laboratory model by differentially heating and cooling the vertical endwalls of a shallow rectangular cavity, rotating about a vertical axis through its centre. In this paper, the flow observed after this system had been allowed to develop to a steady mean state is described. Measurements were made of the velocity and temperature

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Ingram, Grant, David Gregory-Smith, and Neil Harvey. "Investigation of a Novel Secondary Flow Feature in a Turbine Cascade With End Wall Profiling." Journal of Turbomachinery 127, no. 1 (2005): 209–14. http://dx.doi.org/10.1115/1.1812321.

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A novel secondary flow feature, previously unreported for turbine blading as far as the authors are aware, has been discovered. It has been found that it is possible to separate part of the inlet boundary layer on the blade row end wall as it is being over-turned and rolled up into the passage vortex. This flow feature has been discovered during a continuing investigation into the aerodynamic effects of non-axisymmetric end wall profiling. Previous work, using the low speed linear cascade at Durham University, has shown the potential of end wall profiling for reducing secondary losses. The lat

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Ayyalil, Fathima Mohiyaddin, Samantha J. Montague, Sarah Hicks, et al. "Platelet Function in Paroxysmal Nocturnal Haemoglobinuria." Blood 134, Supplement_1 (2019): 4884. http://dx.doi.org/10.1182/blood-2019-130291.

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Introduction Paroxysmal nocturnal haemoglobinuria (PNH) is a rare acquired clonal haematopoietic stem cell disorder characterised by haemolytic anaemia, thrombosis and bone marrow failure. Thrombosis is considered a major cause for high morbidity and mortality in PNH patients (Hillmen P et al N Eng J Med 1995). However, the underlying mechanisms of thrombosis in PNH are still poorly understood. Various factors including defective interactions between the complement system, platelets and coagulation systems have been proposed (Peacock-Young B et al Haematologica 2017). Platelet function and clo

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Wightman, Emma L. "Potential benefits of phytochemicals against Alzheimer's disease." Proceedings of the Nutrition Society 76, no. 2 (2017): 106–12. http://dx.doi.org/10.1017/s0029665116002962.

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Our current therapeutic drugs for Alzheimer's disease are predominantly derived from the alkaloid class of plant phytochemicals. These drugs, such as galantamine and rivastigmine, attenuate the decline in the cholinergic system but, as the alkaloids occupy the most dangerous end of the phytochemical spectrum (indeed they function as feeding deterrents and poisons to other organisms within the plant itself), they are often associated with unpleasant side effects. In addition, these cholinesterase inhibiting alkaloids target only one system in a disorder, which is typified by multifactorial defi

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Grobbe, N., and S. Barde-Cabusson. "Self-Potential Studies in Volcanic Environments: A Cheap and Efficient Method for Multiscale Fluid-Flow Investigations." International Journal of Geophysics 2019 (October 20, 2019): 1–19. http://dx.doi.org/10.1155/2019/2985824.

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We demonstrate the value of using the self-potential method to study volcanic environments, and particularly fluid flow in those environments. We showcase the fact that self-potential measurements are a highly efficient way to map large areas of volcanic systems under challenging terrain conditions, where other geophysical techniques may be challenging or expensive to deploy. Using case studies of a variety of volcano types, including tuff cones, shield volcanoes, stratovolcanoes, and monogenetic fields, we emphasize the fact that self-potential signals enable us to study fluid flow in volcani

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Sun, T., J. Xu, and Z. F. Yang. "Environmental flow assessments in estuaries based on an integrated multi-objective method." Hydrology and Earth System Sciences 17, no. 2 (2013): 751–60. http://dx.doi.org/10.5194/hess-17-751-2013.

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Abstract. An integrated multi-objective method for environmental flow assessments was developed that considered variability of potential habitats as a critical factor in determining how ecosystems respond to hydrological alterations. Responses of habitat area, and the magnitude of those responses as influenced by salinity and water depth, were established and assessed according to fluctuations in river discharge and tidal currents. The requirements of typical migratory species during pivotal life-stage seasons (e.g., reproduction and juvenile growth) and natural flow variations were integrated

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Trevisani, Sebastiano, and Marco Cavalli. "Topography-based flow-directional roughness: potential and challenges." Earth Surface Dynamics 4, no. 2 (2016): 343–58. http://dx.doi.org/10.5194/esurf-4-343-2016.

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Abstract. Surface texture analysis applied to high-resolution digital terrain models (HRDTMs) is a promising approach for extracting useful fine-scale morphological information. Surface roughness, considered here as a synonym of surface texture, can have a discriminant role in the detection of different geomorphic processes and factors. Very often, the local morphology presents, at different scales, anisotropic characteristics that could be taken into account when calculating or measuring surface roughness. The high morphological detail of HRDTMs permits the description of different aspects of

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LIN, PENGZHI, YINNA WU, JUNLI BAI, and QUANHONG LIN. "A NUMERICAL STUDY OF DAM-BREAK FLOW AND SEDIMENT TRANSPORT FROM A QUAKE LAKE." Journal of Earthquake and Tsunami 05, no. 05 (2011): 401–28. http://dx.doi.org/10.1142/s1793431111001169.

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Dam-break flows are simulated numerically by a two-dimensional shallow-water-equation model that combines a hydrodynamic module and a sediment transport module. The model is verified by available analytical solutions and experimental data. It is demonstrated that the model is a reliable tool for the simulation of various transient shallow water flows and the associated sediment transport and bed morphology on complex topography. The validated model is then applied to investigate the potential dam-break flows from Tangjiashan Quake Lake resulting from Wenchuan Earthquake in 2008. The dam-break

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Trevisani, S., and M. Cavalli. "Topography-based flow-directional roughness: potential and challenges." Earth Surface Dynamics Discussions 3, no. 4 (2015): 1399–444. http://dx.doi.org/10.5194/esurfd-3-1399-2015.

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Abstract. Surface texture analysis applied to High Resolution Digital Terrain Models (HRDTMs) is a promising approach for extracting useful fine-scale morphological information. Surface roughness, considered here as a synonym of surface texture, can have a discriminant role in the detection of different geomorphic processes and factors. Very often, the local morphology presents, at different scales, anisotropic characteristics that could be taken into account when calculating or measuring surface roughness. The high morphological detail of HRDTMs permits the description of different aspects of

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Boss, E., N. Paldor, and L. Thompson. "Stability of a potential vorticity front: from quasi-geostrophy to shallow water." Journal of Fluid Mechanics 315 (May 25, 1996): 65–84. http://dx.doi.org/10.1017/s0022112096002339.

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The linear stability of a simple two-layer shear flow with an upper-layer potential vorticity front overlying a quiescent lower layer is investigated as a function of Rossby number and layer depths. This flow configuration is a generalization of previously studied flows whose results we reinterpret by considering the possible resonant interaction between waves. We find that instabilities previously referred to as ‘ageostrophic’ are a direct extension of quasi-geostrophic instabilities.Two types of instability are discussed: the classic long-wave quasi-geostrophic baroclinic instability arising

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Labelle, Alexandre, and Jean-Marc Frayret. "Agent-Based Model for End-of-Life Product Flow Analysis." Resources 7, no. 3 (2018): 42. http://dx.doi.org/10.3390/resources7030042.

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This paper presents an agent-based simulation model for end-of-life product flow analysis in recuperation and recycling supply networks that focuses on individual consumer behaviors. The simulation model is applied to a deposit-return program on wine bottles that could be developed in the province of Quebec. Canadian data was used to calibrate and validate the model. A series of experiments was then conducted with three artificial populations to analyse how they would react to several implementation scenarios of this end-of-life product flow strategy. The results suggest that the distance to t

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Koylu, Caglar, and Diansheng Guo. "Design and evaluation of line symbolizations for origin–destination flow maps." Information Visualization 16, no. 4 (2016): 309–31. http://dx.doi.org/10.1177/1473871616681375.

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We present the results of a user study comparing variants of commonly used line symbolizations for directed origin–destination flow maps. Our design and evaluation consisted of five line symbolizations that employ a combination of following visual variables: arrowheads, origin–destination coloring (color hue, and value), line shortening, line width, tapered edges (varying width from wide to narrow, and narrow to wide), and curvature asymmetry and strength. To guide our evaluation, we used a task-by-type typology and chose four representative tasks that are commonly used in flow map reading: id

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Glöser-Chahoud, Simon, and Frank Schultmann. "Potential Contribution of Secondary Materials to Overall Supply - The Example of the European Cobalt Cycle." Materials Science Forum 959 (June 2019): 11–21. http://dx.doi.org/10.4028/www.scientific.net/msf.959.11.

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Higher efficiency in raw material recycling is discussed as a key strategy to decrease the environmental impact of resource consumption and to improve materials’ availability in order to mitigate supply risks. However, particularly in the case of technology metals, demand is driven by specific emerging technologies from which recycling will not be possible before the end of their useful lifetimes. Hence, the availability of secondary materials is limited by the amount of obsolete products as well as their collection, separation and treatment during waste management and recycling. In this paper

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FRANCO, ELISA, DAVID N. PEKAREK, JIFENG PENG, and JOHN O. DABIRI. "Geometry of unsteady fluid transport during fluid–structure interactions." Journal of Fluid Mechanics 589 (October 8, 2007): 125–45. http://dx.doi.org/10.1017/s0022112007007872.

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We describe the application of tools from dynamical systems to define and quantify the unsteady fluid transport that occurs during fluid–structure interactions and in unsteady recirculating flows. The properties of Lagrangian coherent structures (LCS) are used to enable analysis of flows with arbitrary time-dependence, thereby extending previous analytical results for steady and time-periodic flows. The LCS kinematics are used to formulate a unique, physically motivated definition for fluid exchange surfaces and transport lobes in the flow. The methods are applied to numerical simulations of t

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Hsia, Carleton JC, and Li Ma. "SOD3-Mimetic As a Complement for Genetic Therapy in Sickle Cell Disease." Blood 132, Supplement 1 (2018): 2355. http://dx.doi.org/10.1182/blood-2018-99-120287.

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Abstract Background and Objectives: Genetic therapy relieves transfusion-dependence in patients 12 years and older with ß-Thalassemia (1) There is an urgent need to develop a complementary approach to genetic therapy for children younger than 12 years of age. The objective of this report is to describe the potential development of an extracellular superoxide dismutase-mimetic (SOD3-mimetic) to relieve sickle cell disease (SCD) children susceptible to stroke from being transfusion-dependent in order to avoid stroke. SanFlow [aka polynitroxylated pegylated hemoglobin (PNPH)], a SOD3-mimetic has

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Chang, Chih-Hua. "Numerical Analyses of Wave Generation and Vortex Formation under the Action of Viscous Fluid Flows over a Depression." Journal of Marine Science and Engineering 7, no. 5 (2019): 141. http://dx.doi.org/10.3390/jmse7050141.

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Transient free-surface deformations and evolving vortices due to the passage of flows over a submerged cavity are simulated. A two-dimensional stream function–vorticity formulation with a free-surface model is employed. Model results are validated against the limiting case of pure lid-driven cavity flow with comparisons of the vortical flow pattern and velocity profiles. The verification of the free-surface computations are also carried out by comparing results with published potential flow solutions for cases of flows over a depressed bottom topography. The agreements are generally good. Inve

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Frank, F., B. W. McArdell, C. Huggel, and A. Vieli. "The importance of entrainment and bulking on debris flow runout modeling: examples from the Swiss Alps." Natural Hazards and Earth System Sciences 15, no. 11 (2015): 2569–83. http://dx.doi.org/10.5194/nhess-15-2569-2015.

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Abstract. This study describes an investigation of channel-bed entrainment of sediment by debris flows. An entrainment model, developed using field data from debris flows at the Illgraben catchment, Switzerland, was incorporated into the existing RAMMS debris-flow model, which solves the 2-D shallow-water equations for granular flows. In the entrainment model, an empirical relationship between maximum shear stress and measured erosion is used to determine the maximum potential erosion depth. Additionally, the average rate of erosion, measured at the same field site, is used to constrain the er

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Walton, Gabriel, Georgia Fotopoulos, and Robert Radovanovic. "Extraction and Comparison of Spatial Statistics For Geometric Parameters of Sedimentary Layers from Static and Mobile Terrestrial Laser Scanning Data." Environmental and Engineering Geoscience 25, no. 2 (2019): 155–68. http://dx.doi.org/10.2113/eeg-2068.

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ABSTRACT Terrestrial laser scanning (TLS) is a surveying technology that has seen increasing use in the field of geosciences in recent years. One potential application for this technology is to aid in quantitative stratigraphy. Given a point cloud containing multiple lithologies, the points associated with a specific lithology can be analyzed to quantify the geometric characteristics of that lithology, such as apparent dip, thickness, and spacing. In this study, a semi-automated work flow to perform such a characterization is presented and applied to a case study from an oil sands pit mine in

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