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1

Dulikravich, George S. Theory of unsteady compressible irrotational flows including heat conductivity and longitudinal viscosity. New York: American Institute of Aeronautics and Astronautics, 1988.

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2

Chaffin, Mark S. Navier-Stokes and potential theory solutions for a helicopter fuselage and comparison with experiment. Hampton, Va: Langley Research Center, 1994.

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3

Wenyang, Duan, ed. Chuan bo zai bo lang zhong yun dong de shi liu li lun: Potential flow theory of ship motions in waves. Beijing Shi: Guo fang gong ye chu ban she, 2008.

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4

World Bank. Global Development Finance 2006 (Complete Print Edition): The Development Potential of Surging Capital Flows. Washington, D.C: The World Bank, 2006.

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5

Wentworth, Richard A., Duong H. Phong, Paul M. N. Feehan, Jian Song, and Ben Weinkove. Analysis, complex geometry, and mathematical physics: In honor of Duong H. Phong : May 7-11, 2013, Columbia University, New York, New York. Providence, Rhode Island: American Mathematical Society, 2015.

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6

L, Ashby Dale, and Ames Research Center, eds. Potential flow theory and operation guide for the panel code PMARC. Moffett Field, Calif: National Aeronautics and Space Administration, Ames Research Center, 1991.

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7

Kuo-Yen, Szema, and Langley Research Center, eds. Nonlinear potential analysis techniques for supersonic aerodynamic design. Hampton, Va: National Aeronautics and Space Administration, Langley Research Center, 1985.

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8

1934-, Jameson Antony, and United States. National Aeronautics and Space Administration., eds. Control theory based airfoil design for potential flow and a finite volume discretization. [Washington, DC: National Aeronautics and Space Administration, 1995.

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9

Control theory based airfoil design for potential flow and a finite volume discretization. [Washington, DC: National Aeronautics and Space Administration, 1995.

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10

Research Institute for Advanced Computer Science (U.S.), ed. Control theory based airfoil design using the Euler equations. [Moffett Field, Calif.]: Research Institute for Advanced Computer Science, NASA Ames Research Center, 1994.

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11

United States. National Aeronautics and Space Administration., ed. Small-amplitude disturbances in turbomachine flows with swirl. [Washington, DC: National Aeronautics and Space Administration, 1994.

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12

United States. National Aeronautics and Space Administration., ed. Small-amplitude disturbances in turbomachine flows with swirl. [Washington, DC: National Aeronautics and Space Administration, 1994.

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13

Small-amplitude disturbances in turbomachine flows with swirl. [Washington, DC: National Aeronautics and Space Administration, 1994.

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14

D, Berry John, and Langley Research Center, eds. Navier-Stokes and potential theory solutions for a helicopter fuselage and comparison with experiment. Hampton, Va: National Aeronautics and Space Administration, Langley Research Center, 1994.

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15

D, Berry John, and Langley Research Center, eds. Navier-Stokes and potential theory solutions for a helicopter fuselage and comparison with experiment. Hampton, Va: National Aeronautics and Space Administration, Langley Research Center, 1994.

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16

D, Berry John, and Langley Research Center, eds. Navier-Stokes and potential theory solutions for a helicopter fuselage and comparison with experiment. Hampton, Va: National Aeronautics and Space Administration, Langley Research Center, 1994.

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17

D, Berry John, and Langley Research Center, eds. Navier-Stokes and potential theory solutions for a helicopter fuselage and comparison with experiment. Hampton, Va: National Aeronautics and Space Administration, Langley Research Center, 1994.

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18

Clarke, Andrew. Energy flow in organisms. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780199551668.003.0004.

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An organism is an open thermodynamic system exchanging both energy and materials with its environment. Organisms exchange energy with their environment by radiation, conduction, convection and evaporation of water. The relative importance of these varies with the organism and its situation. Newton’s Law of Cooling is a simplification that is useful only for warm endotherms in a still, cool environment. For all other circumstances a full biophysical treatment is necessary. Flows of chemical potential energy can be captured by a balanced energy budget. A full description of the energy balance of an organism requires the coupling of a biophysical model of heat flow with an energy budget model. This combination provides a powerful tool for modelling the thermal and energetic niches of organisms, and to predict how these might change in the future.
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19

Succi, Sauro. Kinetic Theory of Dense Fluids. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199592357.003.0007.

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This chapter presents the basic elements of the kinetic theory of non-ideal fluids, to which both kinetic and potential energy contribute on comparable footing. Non-ideal fluids lie at the heart of many complex fluid-dynamic applications, such as those involving multiphase and multicomponent flows. This chapter features a degree of abstraction which may not come by handy to the reader with limited interest to the formal theory of classical many-body systems. The interested readers can safely skip the math and retain the basic bottomline. They may just skip this chapter altogether, but in this author’s opinion, this is likely to come with a toll on the full appreciation of Lattice Boltzmann theory for non-ideal fluids, in fact one of the most successful offsprings of Lattice Boltzmann theory.
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20

Frankham, Richard, Jonathan D. Ballou, Katherine Ralls, Mark D. B. Eldridge, Michele R. Dudash, Charles B. Fenster, Robert C. Lacy, and Paul Sunnucks. Genetic rescue by augmenting gene flow. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198783398.003.0006.

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Inbreeding is reduced and genetic diversity enhanced when a small isolated inbred population is crossed to another unrelated population. Crossing can have beneficial or harmful effects on fitness, but beneficial effects predominate, and the risks of harmful ones (outbreeding depression) can be predicted and avoided. For crosses with a low risk of outbreeding depression, there are large and consistent benefits on fitness that persist across generations in outbreeding species. Benefits are greater in species that naturally outbreed than those that inbreed, and increase with the difference in inbreeding coefficient between crossed and inbred populations in mothers and zygotes. However, benefits are similar across invertebrates, vertebrates and plants. There are also important benefits for evolutionary potential of crossing between populations.
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21

Strang, Veronica. Re-Imagined Communities. Edited by Ken Conca and Erika Weinthal. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199335084.013.4.

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Focusing on water as a connective material flow, this chapter reconsiders notions of community, agency, and identity from the perspective of contemporary debates on ecological ethics and relationality. By articulating the fluid relationships between humans, nonhumans, and the material world, these debates critique dominant conceptual assumptions about Nature and Culture as separate domains. Such assumptions continue to underpin water policy and management, casting ecosystems—and their dependent species—as the subjects of human action, with generally poor outcomes for their well-being. The chapter draws on actor-network theory, philosophical ideas about ethics, and analyses of materiality to propose a re-imagined model of “community” that reintegrates the human and nonhuman, and opens up the potential for more reciprocal—and thus more sustainable—human‒environmental relationships. In doing so, it proposes a new kind of “participatory” framework for water policy development.
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22

TranAir, a full-potential, solution-adaptive, rectangular grid code for predicting subsonic, transonic, and supersonic flows about arbitrary configurations: Theory document. [Washington, D.C.]: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Program, 1992.

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23

TranAir, a full-potential, solution-adaptive, rectangular grid code for predicting subsonic, transonic, and supersonic flows about arbitrary configurations: Theory document. [Washington, D.C.]: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Program, 1992.

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24

T, Johnson F., and United States. National Aeronautics and Space Administration. Scientific and Technical Information Program., eds. TranAir, a full-potential, solution-adaptive, rectangular grid code for predicting subsonic, transonic, and supersonic flows about arbitrary configurations: Theory document. [Washington, D.C.]: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Program, 1992.

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25

Jacobsen, Dean, and Olivier Dangles. Energy flow and species interactions at the edge. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198736868.003.0007.

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Chapter 7 elucidates the relationships between the structure and functioning of aquatic ecosystems at high altitude through the description of material cycles and food webs. Following the landscape continuum model, material cycling is profoundly influenced by the physical structure of the waterscape (e.g. vegetation cover); as a result a great diversity of energetic pathways characterize high altitude waterscapes, along an autotrophy–heterotrophy gradient. Similarly, high altitude aquatic food webs embrace a great diversity of trophic compartments, feeding strategies, and processes (trophic cascades and terrestrial subsidiarity) that are profoundly shaped by environmental harshness. Harsh conditions also generate stress gradients along which the strength and direction of species interactions (from competition to facilitation) and their functional role (e.g. as ecosystem engineers) are modified. The resulting structural and functional changes affect in turn species coexistence and trigger potential ecosystem shifts.
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26

Noggle, James. Unfelt. Cornell University Press, 2020. http://dx.doi.org/10.7591/cornell/9781501747120.001.0001.

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This book offers a new account of feeling during the British Enlightenment, finding that the passions and sentiments long considered as preoccupations of the era depend on a potent insensibility, the secret emergence of pronounced emotions that only become apparent with time. Surveying a range of affects, including primary sensation, love and self-love, greed, happiness, and patriotic ardor, the book explores literary evocations of imperceptibility and unfeeling that pervade and support the period's understanding of sensibility. Each of the four sections of the book—on philosophy, the novel, historiography, and political economy—charts the development of these idioms from early in the long eighteenth century to their culmination in the age of sensibility. From Locke to Eliza Haywood, Henry Fielding, and Frances Burney, and from Dudley North to Hume and Adam Smith, the book's exploration of the insensible dramatically expands the scope of affect in the period's writing and thought. Drawing inspiration from contemporary affect theory, the book charts how feeling and unfeeling flow and feed back into each other, identifying emotional dynamics at their most elusive and powerful: the potential, the incipient, the emergent, and the virtual.
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27

Network Flows and Monotropic Optimization. Athena Scientific, 1998.

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28

Kimura, T., and Y. Otani. Magnetization switching due to nonlocal spin injection. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198787075.003.0021.

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This chapter discusses and presents a schematic illustration of nonlocal spin injection. In this case, the spin-polarized electrons are injected from the ferromagnet and are extracted from the left-hand side of the nonmagnet. This results in the accumulation of nonequilibrium spins in the vicinity of the F/N junctions. Since the electrochemical potential on the left-hand side is lower than that underneath the F/N junction, the electron flows by the electric field. On the right-hand side, although there is no electric field, the diffusion process from the nonequilibrium into the equilibrium state induces the motion of the electrons. Since the excess up-spin electrons exist underneath the F/N junction, the up-spin electrons diffuse into the right-hand side. On the other hand, the deficiency of the down-spin electrons induces the incoming flow of the down-spin electrons opposite to the motion of the up-spin electron.
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29

Kruusmaa, Maarja. From aquatic animals to robot swimmers. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0044.

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Fish and other aquatic animals have developed a diverse repertoire of locomotion and sensing strategies in an environment that is 800 times denser than air. This chapter explains the underlying principles of aquatic locomotion and describes some landmark biomimetic robots based on those principles. Biological underwater swimmers face the trade-off between speed and manoeuvrability and it is argued that the same trade-off exists also with biomimetic vehicles. Biomimetic underwater vehicles mostly mimic carangiform and subcarangiform swimmers which are fast swimmers. The highly manoeuvrable fish species (lampreys, rays, etc.) are a less popular choice of bioinspiration arguably because of their higher complexity and limitations posed by current technology of electromechanical devices. A unique sensing organ, the lateral line, is utilized by all fish species. Artifical lateral lines for sensing flow are briefly discussed as well as the potential of robot control with the help of flow sensing.
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30

Swyngedouw, Erik. Social Power and the Urbanization of Water. Oxford University Press, 2004. http://dx.doi.org/10.1093/oso/9780198233916.001.0001.

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Taking as his case-study the city of Guayaquil in Ecuador, where 600,000 people lack easy access to potable water, Erik Swyngedouw aims to reconstruct, theoretically and empirically, the political, social, and economic conduits through which water flows, and to identify how power relations infuse the metabolic transformation of water as it becomes urban. These flows of water which are simultaneously physical and social carry in their currents the embodiment of myriad social struggles and conflicts. The excavation of these flows narrates stories about the city's structure and development. Yet these flows also carry the potential for an improved, more just, and more equitable right to the city and its water. The flows of power that are captured by urban water circulation also suggest that the question of urban sustainability is not just about achieving sound ecological and environmental conditions, but first and foremost about a social struggle for access and control; a struggle not just for the right to water, but for the right to the city itself.
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31

Weimann, Gabriel. Terrorism and Counterterrorism on the Internet. Oxford University Press, 2018. http://dx.doi.org/10.1093/acrefore/9780190846626.013.420.

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The internet has emerged as an important medium for terrorists. Two key trends can be discerned from cyberterrorism: the democratization of communications driven by user generated content on the internet, and modern terrorists’ growing awareness of the internet’s potential for their purposes. The internet has become a favorite tool of the terrorists because of the many advantages it provides, such as easy access; little or no regulation, censorship, or other forms of government control; potentially huge audiences spread throughout the world; anonymity of communication; fast flow of information; interactivity; inexpensive development and maintenance of a Web presence; a multimedia environment; and the ability to influence coverage in the traditional mass media. These advantages make the network of computer-mediated communication ideal for terrorists-as-communicators. Terrorist groups of all sizes maintain their own websites to spread propaganda, raise funds and launder money, recruit and train members, communicate and conspire, plan and launch attacks. They also rely on e-mail, chatrooms, e-groups, forums, virtual message boards, and resources like YouTube, Facebook, and Google Earth. Fighting online terrorism raises the issue of countermeasures and their cost. The virtual war between terrorists and counterterrorism forces and agencies is certainly a vital, dynamic, and ferocious one. It is imperative that we become better informed about the uses to which terrorists put the internet and better able to monitor their activities. Second, we must defend our societies better against terrorism without undermining the very qualities and values that make our societies worth defending.
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32

Kortgen, Andreas, and Michael Bauer. Hepatic function in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0175.

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The liver with its parenchymal and non-parenchymal cells plays a key role in the organism with manifold functions of metabolism, synthesis, detoxification, excretion, and host response. This requires a portfolio of different tests to obtain an overview of hepatic function. In the critically ill hepatic dysfunction is common and potentially leading to extrahepatic organ dysfunctions culminating in multi-organ failure. Conventional laboratory measures are used to evaluate hepatocellular damage, cholestasis, or synthesis. They provide valuable (differential) diagnostic data and can yield prognostic information in chronic liver diseases, especially when used in scoring systems such as the ‘model for end-stage liver disease’. However, they have short-comings in the critically ill in assessing rapid changes in hepatic function and liver blood flow. In contrast, dynamic quantitative liver function tests measure current liver function with respect to the ability to eliminate and/or metabolize a specific substance. In addition, they are dependent on sinusoidal blood flow. Liver function tests have prognostic significance in the critically ill and may be used to guide therapy.
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33

Blockley, David. 4. Understanding structure. Oxford University Press, 2014. http://dx.doi.org/10.1093/actrade/9780199671939.003.0004.

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‘Understanding structure’ considers the science of how structures work. How do structures resist all of the demands made on them by forces of self-weight, people moving about, or wind that may blow a hurricane? These forces have to ‘flow-though’ the components of the structure. Some simple structures are statically determinate so the internal forces can be calculated by just making sure all of the forces are in equilibrium. More complex structures have too many unknowns to be solved this way—they are statically indeterminate. The internal forces in these structures are found by satisfying the three conditions of equilibrium, constitutive relations, and compatibility of displacements when the total potential is a minimum.
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34

Waldmann, Carl, Neil Soni, and Andrew Rhodes. Respiratory monitoring. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199229581.003.0006.

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Pulmonary function tests in critical illness 90End-tidal CO2 monitoring 92Pulse oximetry 94Pulmonary function test results in critically ill patients can be important prognostically and guide ventilatory and weaning strategies. However, they are not straightforward to measure in mechanically ventilated patients and remain limited to dynamic volumes. Fortunately, most modern mechanical ventilators are able to calculate and display static and dynamic lung volumes, together with derived values for airway resistance, compliance and flow/volume/time curves. The ability to monitor these changes after altering ventilatory parameters has enabled more sophisticated adjustments of ventilation, to prevent potentially damaging mechanical ventilation....
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35

Larmer, Miles. At the Crossroads. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199935369.013.20.

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The Copperbelt region of Central Africa sits at the crossroads of political borders, trade corridors, migratory flows, and identity formations. The division of the region by a colonial/national border shaped not only its differential political economy, but also how this was perceived and represented. At the heart of all such representations was the relationship between minerals and their supposed capacity to effect economic, political, and social transformation. This article analyzes how this relationship has been understood and articulated from the precolonial period until today, and the ways that actual and potential mineral wealth have underwritten successive, often contested, political projects and aspirations. In identifying changes and enduring patterns in mining-based political representation, it suggests an alternative history of the Copperbelt region rooted in the political imaginaries surrounding mining and its potential for transformation.
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36

Douglas, Kenneth. Bioprinting. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190943547.001.0001.

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Abstract: This book describes how bioprinting emerged from 3D printing and details the accomplishments and challenges in bioprinting tissues of cartilage, skin, bone, muscle, neuromuscular junctions, liver, heart, lung, and kidney. It explains how scientists are attempting to provide these bioprinted tissues with a blood supply and the ability to carry nerve signals so that the tissues might be used for transplantation into persons with diseased or damaged organs. The book presents all the common terms in the bioprinting field and clarifies their meaning using plain language. Readers will learn about bioink—a bioprinting material containing living cells and supportive biomaterials. In addition, readers will become at ease with concepts such as fugitive inks (sacrificial inks used to make channels for blood flow), extracellular matrices (the biological environment surrounding cells), decellularization (the process of isolating cells from their native environment), hydrogels (water-based substances that can substitute for the extracellular matrix), rheology (the flow properties of a bioink), and bioreactors (containers to provide the environment cells need to thrive and multiply). Further vocabulary that will become familiar includes diffusion (passive movement of oxygen and nutrients from regions of high concentration to regions of low concentration), stem cells (cells with the potential to develop into different bodily cell types), progenitor cells (early descendants of stem cells), gene expression (the process by which proteins develop from instructions in our DNA), and growth factors (substances—often proteins—that stimulate cell growth, proliferation, and differentiation). The book contains an extensive glossary for quick reference.
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37

Cates, M. Complex fluids: the physics of emulsions. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198789352.003.0010.

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These lectures start with the mean field theory for a symmetric binary fluid mixture, addressing interfacial tension, the stress tensor, and the equations of motion (Model H). We then consider the phase separation kinetics of such a mixture: coalescence, Ostwald ripening, its prevention by trapped species, coarsening of bicontinuous states, and the role of shear flow. The third topic addressed is the stabilization of emulsions by using surfactants to reduce or even eliminate the interfacial tension between phases; the physics of bending energy, which becomes relevant in the latter case, is then presented briefly. The final topic is the creation of long-lived metastable emulsions by adsorption of colloidal particles or nanoparticles at the fluid–fluid interface; alongside spherical droplets, these methods can be used to create a range of unconventional structures with potentially interesting properties that are only now being explored.
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38

Steward, David R. Analytic Element Method. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198856788.001.0001.

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The Analytic Element Method provides a foundation to solve boundary value problems commonly encountered in engineering and science. The goals are: to introduce readers to the basic principles of the AEM, to provide a template for those interested in pursuing these methods, and to empower readers to extend the AEM paradigm to an even broader range of problems. A comprehensive paradigm: place an element within its landscape, formulate its interactions with other elements using linear series of influence functions, and then solve for its coefficients to match its boundary and interface conditions with nearly exact precision. Collectively, sets of elements interact to transform their environment, and these synergistic interactions are expanded upon for three common types of problems. The first problem studies a vector field that is directed from high to low values of a function, and applications include: groundwater flow, vadose zone seepage, incompressible fluid flow, thermal conduction and electrostatics. A second type of problem studies the interactions of elements with waves, with applications including water waves and acoustics. A third type of problem studies the interactions of elements with stresses and displacements, with applications in elasticity for structures and geomechanics. The Analytic Element Method paradigm comprehensively employs a background of existing methodology using complex functions, separation of variables and singular integral equations. This text puts forth new methods to solving important problems across engineering and science, and has a tremendous potential to broaden perspective and change the way problems are formulated.
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39

Thomas, David F. M. Vesicoureteric reflux. Edited by David F. M. Thomas. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0115.

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The term vesicoureteric reflux (VUR) describes the retrograde flow of urine from the bladder into the upper urinary tract. VUR is not a disease entity in its own right. Nevertheless, it has the potential to cause significant morbidity by preventing effective emptying of the urinary tract and by facilitating the transport of bacteria into the upper tract and renal parenchyma. Mechanisms of renal damage associated with VUR include pyelonephritic scarring and congenital dysplasia or hypoplasia. The long-term complications of pyelonephritic scarring may include hypertension, renal failure, and an increased risk of complications during pregnancy. VUR of mild or moderate severity is best managed conservatively and surgical intervention is generally reserved for failed medical management and high grade or complex VUR. Although the introduction of endoscopic correction has revolutionized surgical management, there remains a role for open surgery for the correction of higher grades of reflux.
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40

Allon, Michael. Haemodialysis. Edited by Jonathan Himmelfarb. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0256.

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Delivery of haemodialysis is dependent on having a vascular access that can reproducibly deliver an adequate blood flow thrice weekly. None of the three types of vascular access is perfect; each has potential advantages and drawbacks. Fistulas are the preferred type of vascular access because they have the longest cumulative survival and require the fewest interventions to maintain their long-term patency, once they achieve suitability for dialysis. However, fistulas have a fairly high non-maturation rate, frequently require revisions to achieve suitability for dialysis, and often are associated with prolonged catheter dependence until they are ready to cannulate. In contrast, grafts have a lower primary failure rate, are usually ready to use within 2–3 weeks of creation, and are therefore associated with a shorter duration of catheter dependence. However, the cumulative survival of grafts is shorter than that of fistulas, and they require more frequent interventions (angioplasty, thrombectomy, or surgical revisions) to maintain their patency for dialysis. The major advantage of dialysis catheters is that they are suitable for use as soon as they are placed. However, catheter use is associated with frequent complications, including catheter-related bacteraemia, dysfunction, and central vein stenosis. Many patients require a tunnelled dialysis catheter as a bridge, until they have a mature fistula or graft. Optimal management of vascular access is extremely challenging, and requires close collaboration among multiple medical disciplines, advance planning, and treatment or prophylaxis of their frequent complications.
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41

Lewington, Andrew, and Michael Weston. Imaging the urinary tract in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0210.

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Imaging the urinary tract of patients in the intensive care unit (ICU) may assist identifying the cause of acute kidney injury (AKI). By the nature of their illness patients on ICU will often be clinically unstable and this will restrict the choice of imaging. Ultrasound is the most commonly used non-invasive imaging technique used, and is essential for assessing renal anatomy, determining kidney size and the presence of obstruction. New developments hold much promise and there are a number of centres now using this technology. Doppler ultrasonography has become increasingly popular to assess intrarenal blood flow. CT scanning can be used with or without contrast when ultrasonography is non-diagnostic and is very useful in identifying calcification within the renal tract. However, the patient must be stable enough for transfer to the radiology department. It is important to consider the risk of iodinated contrast-induced AKI (CI-AKI) in critically-ill patients and minimize potential renal injury. Magnetic resonance imaging may be preferred where there is risk of CI-AKI, but the logistics may prove even more demanding. Renal arteriography is rarely performed, but may be required for diagnostic and interventional procedures for renal artery stenosis or sites of active haemorrhage.
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42

Wise, Matt, and Paul Frost. Role of the intensive care unit. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0148.

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The intensive care unit (ICU) can be defined as an area reserved for patients with potential or established organ failure and has the facilities for the diagnosis, prevention, and treatment of multi-organ failure. Usually, the ICU is located in close proximity to A & E, the radiology department, and the operating theatres, as it is between these areas that patient flows are greatest. In large urban hospitals, there may be more than one ICU, some of which serve specific patient populations, such as paediatrics, neurosurgery, cardiothoracic surgery, liver failure, and burns. Many hospitals also have high-dependency units (HDUs) that offer higher nurse-to-patient ratios and more advanced monitoring than a general wards does, as well as limited organ support. In the UK, the distinctions between ICU, HDU, and general ward have been abandoned in favour of a classification based on the patient’s needs rather than their location.
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43

Kinsella, David, and Alexander H. Montgomery. Arms Supply and Proliferation Networks. Edited by Jennifer Nicoll Victor, Alexander H. Montgomery, and Mark Lubell. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780190228217.013.33.

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Network analyses of global and regional arms flows (including small arms and light weapons, major conventional weapons, and weapons of mass destruction) and related international insecurity and criminality have so far been limited. Yet the literature contains hypotheses that could be explored or tested using network analysis. This chapter discusses supply and demand effects, structural tradeoffs between security and efficiency, pressures to become more or less centralized, and the effects of geography and other network layers. It concludes by reviewing existing data sets and analyses and gauges the potential for network analysis to inform the study of arms transfer networks. Given the general import of these networks for both security studies and policy, there should be a renaissance in the study of arms supply and proliferation networks.
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44

Dietrich, W. Dalton. Physiologic Modulators of Neural Injury After Brain and Spinal Cord Injury. Edited by David L. Reich, Stephan Mayer, and Suzan Uysal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190280253.003.0001.

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Brain and spinal cord injury are leading causes of death and long-term disability, producing diverse burdens for the affected individuals, their families, and society. Such injuries, including traumatic brain injury, stroke, subarachnoid hemorrhage, and spinal cord injury, have common patterns of neuronal cell vulnerability that are associated with a complex cascade of pathologic processes that trigger the propagation of tissue damage beyond the acute injury. Secondary injury mechanisms, including oxidative stress, edema formation, changes in cerebral blood flow and vessel reactivity, metabolic and blood–brain barrier disruption, and neuroinflammation, are therefore important therapeutic targets. Several key physiological parameters require monitoring and intensive management during various phases of treatment to ameliorate secondary injury mechanisms and potentially protect against further neuronal injury. This chapter reviews the core physiological targets in the management of brain and spinal cord injury and relates them to secondary injury mechanisms and outcomes.
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45

Ron, James, Shannon Golden, David Crow, and Archana Pandya. Resources. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780199975044.003.0004.

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This chapter examines the persistence of the top-down foreign funding resource pattern for local human rights organizations (LHROs) in the global South. Local publics have generally high levels of support for human rights ideas and organizations, and they do make donations to other causes. Despite this high potential for local donations, almost all LHRO funding flows from northern institutions. Part of the explanation lies in socially constructed philanthropic routines: individuals prioritize donations to “tangible” charities rather to organizations that support policy, advocacy, and legal work, and LHROs pursue international resources, rather than engage in costly domestic fundraising efforts. The chapter argues that local rights groups face an uncertain future if they do not begin to capitalize on public support. It further suggests that LHROs should—and can—develop a more diverse domestic resource base.
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46

Ren, Ke, and Ronald Dubner. The first crystal structure of an ionotropic glutamate receptor ligand-binding core. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0032.

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The known functional ionotropic glutamate receptors (iGluRs) are composed of three major subtypes: AMPA, NMDA, and kainate. In 1998, in the landmark paper discussed in this chapter, Armstrong et al. provided the first crystal structure of an iGluR-subunit ligand-binding core, the S1S2 region of the rat GluA2 ‘flop’ isoform. They solved its structure with X-ray crystallography from selenomethonine crystals. They also identified residues involved in kainate binding, analysed allosteric sites that regulate affinity and specificity of the agonist, and mapped potential subunit–subunit interaction sites. They also proposed that binding of different agonists may result in variable degrees of domain closure. This work has profound impact on the field and it has been importantly cited. Subsequently, numerous high-resolution crystal structures of ligand-binding domains of iGluRs in complex with ligands, both agonists and antagonists, have been solved.
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47

Yusuf, Moeed. Brokering Peace in Nuclear Environments. Stanford University Press, 2018. http://dx.doi.org/10.11126/stanford/9781503604858.001.0001.

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This book is the first to theorize third party mediation in crises between regional nuclear powers. Its relevance flows from two of the most significant international developments since the end of the Cold War: the emergence of regional nuclear rivalries; and the shift from the Cold War’s bipolar context to today’s unipolar international setting. Moving away from the traditional bilateral deterrence models, the book conceptualizes crisis behavior as “brokered bargaining”: a three-way bargaining framework where the regional rivals and the ‘third party’ seek to influence each other to behave in line with their crisis objectives and in so doing, affect each other’s crisis behavior. The book tests brokered bargaining theory by examining U.S.-led crisis management in South Asia, analyzing three major crises between India and Pakistan: the Kargil conflict, 1999; the 2001-02 nuclear standoff; and the Mumbai crisis, 2008. The case studies find strong evidence of behavior predicted by the brokered bargaining framework. They also shed light on several risks of misperceptions and inadvertence due to the challenges inherent in signaling to multiple audiences simultaneously. Traditional explanations rooted in bilateral deterrence models do not account for these, leaving a void with serious practical consequences, which the introduction of brokered bargaining seeks to fill. The book’s findings also offer lessons for crises on the Korean peninsula, between China and India, and between potential nuclear rivals in the Middle East.
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48

Henstridge, Mark, and Alan Roe. The Macroeconomic Management of Natural Resources. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198817369.003.0008.

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Managing natural resource wealth requires accommodating very large increases in investment, production, exports, and government revenues within the economy of the host country, and setting appropriate macroeconomic policies—especially fiscal, monetary, and exchange-rate policies—both to prevent resource wealth from destabilizing the economy and to ensure that its potential for economic development is maximized. This chapter focuses on the complexity of decision-making and policy on the unusual characteristics of the macroeconomic flows of the extractives sector: (i) foreign direct investment, production, exports, and revenues are often large; (ii) for each project there is a strong degree of uniformity in the sequence of activity from discovery through development to production; (iii) the non-renewable resource is finite, and so are the revenues; (iv) commodity prices are often volatile, hence public revenues can be also volatile.
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49

Holzhauer, Hunter M. Trends and Future Prospects of Hedge Funds. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190607371.003.0030.

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This chapter focuses on new trends in the hedge fund industry. The chapter begins by creating some historical context for the current perception and state of hedge funds. The remainder of this chapter focuses on the following trends and their potential impact on the industry: (1) growth in all areas of the industry, especially in terms of long-term capital flows from institutional investors; (2) uncertainty about growth in the short term; (3) ways hedge funds approach growth; (4) the need for more diversity among hedge fund managers, including more minorities and women; (5) diverging long-term objectives for larger and smaller hedge funds; (6) future cost savings to investors; (7) development of new investment options to address liquidity concerns for investors; (8) new regulations; and (9) the future role of technology in the hedge fund industry.
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50

Cooper, Barbara. Women and Gender. Edited by John Parker and Richard Reid. Oxford University Press, 2013. http://dx.doi.org/10.1093/oxfordhb/9780199572472.013.0018.

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The nineteenth and twentieth centuries were a period of turbulence and change in Africa; men and women navigated that turbulence in part by redefining gender. Power in African societies has historically been linked to seniority determined by age, sexuality, reproductive capacity, spiritual aptitude, physical strength, and wealth. Individuals have acted to reshape their horizons of possibility by jockeying for seniority through shifting means over time. Flows of ideas, peoples, cultures, and goods introduced new constructions of gender that have been adapted and transformed in the African context, generating new avenues of manœuvre through courts, schooling, and markets. No single credible narrative of either ascension or decline can be told about women’s experiences in the history of modern Africa because what it has meant to be a woman has been constantly renegotiated. Male bodies and masculinity have shifted in meaning and potential as well.
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