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Journal articles on the topic "PPod"

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Brown, Sigal Horowitz, James B. Scott, Jeyanthi Bhaheetharan, William C. Sharpee, Lane Milde, Richard A. Wilson, and Nancy P. Keller. "Oxygenase Coordination Is Required for Morphological Transition and the Host–Fungus Interaction of Aspergillus flavus." Molecular Plant-Microbe Interactions® 22, no. 7 (July 2009): 882–94. http://dx.doi.org/10.1094/mpmi-22-7-0882.

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Oxylipins, a class of oxygenase-derived unsaturated fatty acids, are important signal molecules in many biological systems. Recent characterization of an Aspergillus flavus lipoxygenase gene, lox, revealed its importance in maintaining a density-dependent morphology switch from sclerotia to conidia as population density increased. Here, we present evidence for the involvement of four more oxylipin-generating dioxygenases (PpoA, PpoB, PpoC, and PpoD) in A. flavus density-dependent phenomena and the effects of loss of these genes on aflatoxin production and seed colonization. Although several single mutants showed alterations in the sclerotia-to-conidia switch, the major effect was observed in a strain downregulated for all five oxygenases (invert repeat transgene [IRT] strain IRT4 = ppoA, ppoB, ppoC, ppoD, and lox). In strain IRT4, sclerotia production was increased up to 500-fold whereas conidiation was decreased down to 100-fold and the strain was unable to switch into conidial production. Aflatoxin (AF) production for all mutant strains and the wild type was greatest at low population densities and absent in high populations except for strain IRT4, which consistently produced high levels of the mycotoxin. Growth on host seed by both IRT4 and IRT2 (downregulated in ppoA, ppoB, and ppoD) was marked by decreased conidial but increased AF production. We propose that A. flavus oxygenases and the oxylipins they produce act in a highly interdependent network with some redundancy of biological function. These studies provide substantial evidence for oxylipin-based mechanisms in governing fungus–seed interactions and in regulating a coordinated quorum-sensing mechanism in A. flavus.
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Alsirafy, Samy A., Ahmad M. Hammad, Noha Y. Ibrahim, Dina E. Farag, and Omar Zaki. "Preferred Place of Death for Patients With Incurable Cancer and Their Family Caregivers in Egypt." American Journal of Hospice and Palliative Medicine® 36, no. 5 (November 26, 2018): 423–28. http://dx.doi.org/10.1177/1049909118813990.

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Background: Little is known about the place of death of patients with cancer in Eastern Mediterranean countries including Egypt, where palliative care is underdeveloped. Identifying the preferred place of death (PPoD) is important for the development of appropriate palliative care models in these countries. Objectives: To know the PPoD of Egyptian patients with incurable cancer and their family caregivers (FCGs) and to determine the factors that may impact their preferences. Methods: An observational cross-sectional study that included 301 dyads of patients with incurable cancer and one of their FCGs. A questionnaire was designed to collect data about the characteristics of patients and FCGs as well as their preferences. Results: The majority of dyads (272/301, 90.4%) answered the PPoD question. Home was the PPoD in 93% of patients and 90.1% of FCGs ( P = .218). The congruence between patients’ and FCGs’ PPoD was 92.7% (κ = 0.526). In multivariate analysis, poorer performance status (Eastern Cooperative Oncology Group 3 or 4) and full employment of FCGs associated significantly with patients’ preference to die in hospital (odds ratio [OR] = 3.015 [95% confidence interval [CI]: 1.004-9.054], P = .049 and OR = 4.402 [95% CI: 1.561-12.417], P = .005, respectively), while poorer performance status and nonreferral to the palliative medicine unit were associated with FCGs’ preference of hospital death (OR = 2.705 [95% CI: 1.105-6.626], P = .029 and OR = 2.537 [95% CI: 1.082-5.948], P = .032, respectively). Conclusions: The results of the current study suggest that home is the PPoD for the vast majority of Egyptian patients with incurable cancer and their FCGs. Palliative care interventions that promote home death of patients with incurable cancer are needed in Egypt.
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Skorstengaard, Marianne Hjorth, Anders Bonde Jensen, Pernille Andreassen, Trine Brogaard, Elisabeth Brendstrup, Anders Løkke, Susanne Aagaard, Henrik Wiggers, and Mette Asbjoern Neergaard. "Advance care planning and place of death, hospitalisation and actual place of death in lung, heart and cancer disease: a randomised controlled trial." BMJ Supportive & Palliative Care 10, no. 4 (April 11, 2019): e37-e37. http://dx.doi.org/10.1136/bmjspcare-2018-001677.

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ObjectivesAdvance care planning (ACP) can be a way to meet patients’ end-of-life preferences and enhance awareness of end-of-life care. Thereby it may affect actual place of death (APOD) and decrease the rate of hospitalisations. The aim was to investigate if ACP among terminally ill patients with lung, heart and cancer diseases effects fulfilment of preferred place of death (PPOD), amount of time spent in hospital and APOD.MethodsThe study was designed as a randomised controlled trial. Patients were assessed using general and disease-specific criteria and randomised into groups: one received usual care and one received usual care plus ACP. The intervention consisted of a discussion between a healthcare professional, the patient and their relatives about preferences for end-of-life care. The discussion was documented in the hospital file.ResultsIn total, 205 patients were randomised, of which 111 died during follow-up. No significant differences in fulfilment of PPOD (35% vs 52%, p=0.221) or in amount of time spent in hospital among deceased patients (49% vs 23%, p=0.074) were found between groups. A significant difference in APOD was found favouring home death in the intervention group (17% vs 40%, p=0.013).ConclusionConcerning the primary outcome, fulfilment of PPOD, and the secondary outcome, time spent in hospital, no differences were found. A significant difference concerning APOD was found, as more patients in the intervention group died at home, compared with the usual care group.Trial registration numberNCT01944813.
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Linsky, Amy M., Kelly Stolzmann, and Mark Meterko. "The Patient Perceptions of Deprescribing (PPoD) Survey: Short-Form Development." Drugs & Aging 37, no. 12 (October 7, 2020): 909–16. http://dx.doi.org/10.1007/s40266-020-00802-w.

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Brodhun, Florian, Stefan Schneider, Cornelia Göbel, Ellen Hornung, and Ivo Feussner. "PpoC from Aspergillus nidulans is a fusion protein with only one active haem." Biochemical Journal 425, no. 3 (January 15, 2010): 553–65. http://dx.doi.org/10.1042/bj20091096.

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In Aspergillus nidulans Ppos [psi (precocious sexual inducer)-producing oxygenases] are required for the production of so-called psi factors, compounds that control the balance between the sexual and asexual life cycle of the fungus. The genome of A. nidulans harbours three different ppo genes: ppoA, ppoB and ppoC. For all three enzymes two different haem-containing domains are predicted: a fatty acid haem peroxidase/dioxygenase domain in the N-terminal region and a P450 haem-thiolate domain in the C-terminal region. Whereas PpoA was shown to use both haem domains for its bifunctional catalytic activity (linoleic acid 8-dioxygenation and 8-hydroperoxide isomerization), we found that PpoC apparently only harbours a functional haem peroxidase/dioxygenase domain. Consequently, we observed that PpoC catalyses mainly the dioxygenation of linoleic acid (18:2Δ9Z,12Z), yielding 10-HPODE (10-hydroperoxyoctadecadienoic acid). No isomerase activity was detected. Additionally, 10-HPODE was converted at lower rates into 10-KODE (10-keto-octadecadienoic acid) and 10-HODE (10-hydroxyoctadecadienoic acid). In parallel, decomposition of 10-HPODE into 10-ODA (10-octadecynoic acid) and volatile C-8 alcohols that are, among other things, responsible for the characteristic mushroom flavour. Besides these principle differences we also found that PpoA and PpoC can convert 8-HPODE and 10-HPODE into the respective epoxy alcohols: 12,13-epoxy-8-HOME (where HOME is hydroxyoctadecenoic acid) and 12,13-epoxy-10-HOME. By using site-directed mutagenesis we demonstrated that both enzymes share a similar mechanism for the oxidation of 18:2Δ9Z,12Z; they both use a conserved tyrosine residue for catalysis and the directed oxygenation at the C-8 and C-10 is most likely controlled by conserved valine/leucine residues in the dioxygenase domain.
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Tsitsigiannis, Dimitrios I., Terri M. Kowieski, Robert Zarnowski, and Nancy P. Keller. "Three putative oxylipin biosynthetic genes integrate sexual and asexual development in Aspergillus nidulans." Microbiology 151, no. 6 (June 1, 2005): 1809–21. http://dx.doi.org/10.1099/mic.0.27880-0.

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Oxylipins called psi factors have been shown to alter the ratio of asexual to sexual sporulation in the filamentous fungus Aspergillus nidulans. Analysis of the A. nidulans genome has led to the identification of three fatty acid oxygenases (PpoA, PpoB and PpoC) predicted to produce psi factors. Here, it is reported that deletion of ppoB (ΔppoB) reduced production of the oleic-acid-derived oxylipin psiBβ and increased the ratio of asexual to sexual spore development. Generation of the triple mutant ΔppoAΔppoBΔppoC resulted in a strain deficient in producing oleic- and linoleic-acid-derived 8′-hydroxy psi factor and caused increased and mis-scheduled activation of sexual development. Changes in asexual to sexual spore development were positively correlated to alterations in the expression of brlA and veA, respectively. PpoB and/or its products antagonistically mediate the expression levels of ppoA and ppoC, thus revealing regulatory feedback loops among these three genes. Phylogenetic analyses showed that ppo genes are present in both saprophytic and pathogenic Ascomycetes and Basidiomycetes, suggesting a conserved role for Ppo enzymes in the life cycle of fungi.
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Molina-Quintero, Luisa R., Patricia Lucas-Elío, and Antonio Sanchez-Amat. "Regulation of the Marinomonas mediterranea Antimicrobial Protein Lysine Oxidase by l-Lysine and the Sensor Histidine Kinase PpoS." Applied and Environmental Microbiology 76, no. 18 (July 23, 2010): 6141–49. http://dx.doi.org/10.1128/aem.00690-10.

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ABSTRACT Some Gram-negative bacteria express a novel enzyme with lysine-ε-oxidase (LOD) activity (EC 1.4.3.20). The oxidation of l-Lys generates, among other products, hydrogen peroxide, which confers antimicrobial properties to this kind of enzyme and has been shown to be involved in cell death during biofilm development and differentiation. In addition to LOD, the melanogenic marine bacterium Marinomonas mediterranea, which forms part of the microbiota of the marine plant Posidonia oceanica, expresses two other oxidases of biotechnological interest, a multicopper oxidase, PpoA, with laccase activity and a tyrosinase named PpoB, which is responsible for melanin synthesis. By using both lacZ fusions with the lodAB promoter and quantitative reverse transcription-PCR (qRT-PCR), this study shows that the hybrid sensor histidine kinase PpoS regulates LOD activity at the transcriptional level. Although PpoS also regulates PpoA and PpoB, in this case, the regulatory effect cannot be attributed only to a transcriptional regulation. Further studies indicate that LOD activity is induced at the posttranscriptional level by l-Lys as well as by two structurally similar compounds, l-Arg and meso-2,6-diaminopimelic acid (DAP), neither of which is a substrate of the enzyme. The inducing effect of these compounds is specific for LOD activity since PpoA and PpoB are not affected by them. This study offers, for the first time, insights into the mechanisms regulating the synthesis of the antimicrobial protein lysine-ε-oxidase in M. mediterranea, which could be important in the microbial colonization of the seagrass P. oceanica.
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Thomsen, Stefan, and Thomas C. G. Bosch. "Foot differentiation and genomic plasticity in Hydra: lessons from the PPOD gene family." Development Genes and Evolution 216, no. 2 (January 10, 2006): 57–68. http://dx.doi.org/10.1007/s00427-005-0032-9.

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Dagenais, Taylor R. T., DaWoon Chung, Steven S. Giles, Christina M. Hull, David Andes, and Nancy P. Keller. "Defects in Conidiophore Development and Conidium-Macrophage Interactions in a Dioxygenase Mutant of Aspergillus fumigatus." Infection and Immunity 76, no. 7 (April 28, 2008): 3214–20. http://dx.doi.org/10.1128/iai.00009-08.

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ABSTRACT Oxygenated fatty acids, or oxylipins, play an essential role in physiological signaling and developmental processes in animals, plants, and fungi. Previous characterization of three Aspergillus fumigatus dioxygenases (PpoA, PpoB, and PpoC), similar in sequence to mammalian cyclooxygenases, showed that PpoA is responsible for the production of the oxylipins 8R-hydroperoxyoctadecadienoic acid and 5S,8R-dihydroxy-9Z,12Z-octadecadienoic acid and that PpoC is responsible for 10R-hydroxy-8E,12Z-hydroperoxyoctadecadienoic acid. Here, Δppo mutants were characterized to elucidate the role of fungal dioxygenases in A. fumigatus development and host interactions. The ΔppoC strain displayed distinct phenotypes compared to those of other Δppo mutants and the wild type, including altered conidium size, germination, and tolerance to oxidative stress as well as increased uptake and killing by primary alveolar macrophages. These experiments implicate oxylipins in pathogen development and suggest that ΔppoC represents a useful model for studying the A. fumigatus-host interaction.
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Siow, Kim Shyong, Arifah Rahman, Amnani Aminuddin, and Pei Yuen Ng. "Effect of Sulfur on Nitrogen-Containing Plasma Polymers in Promoting Osteogenic Differentiation of Wharton’s Jelly Mesenchymal Stem Cells." Sains Malaysiana 50, no. 1 (January 31, 2021): 239–51. http://dx.doi.org/10.17576/jsm-2021-5001-23.

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The role of sulfur and its synergistic effects with nitrogen moieties in mediating stem cell proliferation and differentiation has become of interest to the tissue engineering community due to chemical similarities with the glycosaminoglycans found in human tissues and cells. Glycosaminoglycans are biomolecules known to influence stem cell differentiation, but the roles of sulfur with different oxidation states on nitrogen-containing polymers have not been fully understood nor investigated. In this study, we used the plasma polymerization of 1,7-octadiene (ppOD), n-heptylamine (ppHA), ppHA grafted with vinyl-sulfonate via Michael-type addition (ppHA-SO3), thiophene (ppT), and ppT with air plasma treatment (ppT-air) to produce controlled amounts of nitrogen and sulfur moieties having different oxidation states, as confirmed by x-ray photoelectron spectroscopy. Assays of the proliferation and osteogenic activities of Wharton’s jelly mesenchymal stem cells (WJ-MSCs) showed the highest activities for ppHA, followed by ppHA-SO3, due to high percentages of amines/amides and the absence of SO3 moieties in ppHA. Other plasma polymers showed less proliferation and osteogenic differentiation than the positive control (glass substrate); however, WJ-MSCs grown on ppT-air with its high percentages of SO4 displayed cytoskeletons intensified with actin stress fiber, unlike the thiol-dominated ppT. Finally, the presence of methyl groups in ppOD severely limited WJ-MSCs proliferation and differentiation. Overall, these results confirm the beneficial effects of amine/amide groups on WJ-MSCs proliferation and osteogenic differentiation, but the combination of these groups with sulfur of various oxidation states failed to further enhance such cellular activities.
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Dissertations / Theses on the topic "PPod"

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Neri, Luca. "Studio di un sistema P-POD per CubeSat 1U e realizzazione modello per test a terra." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018.

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Il progetto di tesi si articola su tre argomenti inerenti al progetto Cubesat, sviluppato nei laboratori universitari. La prima parte è dedicata a tutte le fasi di progetto che hanno portato allo sviluppo di un supporto, Test Pod, per testare il satellite a terra nelle condizioni in cui si troverebbe nella fase di messa in orbita, ossia forti accelerazioni su più assi. In seguito, si è proceduto con il disegno e la verifica tramite simulazioni al computer del PPod, sistema che dovrebbe realmente racchiudere il satellite durante la fase di volo sul razzo ed effettuare il rilascio una volta in orbita. L’ultima parte consiste nell’analisi di un sistema di dispiegamento delle antenne di telecomunicazione, in particolare, sulle possibili configurazioni per ridurre al minimo le forze di attrito fra le parti in movimento.
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Rajnoch, Dalibor. "Návrh PPO na zvolené části toku." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2015. http://www.nusl.cz/ntk/nusl-227481.

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The diploma thesis copes with the evaluation of status quo and further proposal for a flood control arrangements for the river Dřevnice (Zlín district). The evaluation as such has been made by the hydraulic calculation of flow alongside 2D numeric model - SMS-TUFLOW software was used for these calculations and sub-calculations. Based on the results as evaluated by numerical model, the proposal for a flood control arrangements has been made and is further available within the document. Last not least, the utilization of the aforementioned arrangements was measured and described.
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Chou, Nan-yen. "Regulation of branching by phytochrome B and PPFD in Arabidopsis thaliana." Texas A&M University, 2008. http://hdl.handle.net/1969.1/85986.

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The branching or tillering of crops is an important agronomic trait with a major impact on yield. Maintaining an appropriate number of branches allows the plant to use limited light resources and to produce biomass or yield more effectively. The branching process includes the initiation of the axillary meristem leading to bud formation and the further outgrowth of the axillary buds. Phytohormones, including cytokinins and auxin, are known to play major roles in regulating axillary bud outgrowth. Light signals, including light quantity and light quality, are among the most important factors regulating plant growth and are perceived by the action of specialized photoreceptors, including phytochromes. Phytochromes sense red (R) and far-red (FR) light and allow some plants to perceive and respond to competing neighbors by evoking the shade avoidance syndrome (SAS). One component of the SAS is inhibition of branching. Phytochrome B (phyB) is especially important in sensing shade signals and loss of phyB function results in a constitutive shade avoidance phenotype, including reduced branching. While it has been anecdotally reported that phyB-deficient Arabidopsis branches less than wild type, a detailed study of the defects in the process is lacking. In this research, the interactions between light signals, phytochromes and phytohormones in the regulation of branching were assessed using an integrated physiological, molecular and genetic approach.
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Davids, Lester M. "Mitochondrial targeting of wild-type and mutant human protoporphyrinogen oxidase (PPOX)." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/3374.

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YOSHII, SAIJI, IZUMI NAKASHIMA, KOICHI ANDO, HIIZU AOKI, KATSUYA KATO, and MASAO IINUMA. "Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD." Nagoya University School of Medicine, 1988. http://hdl.handle.net/2237/17502.

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Cyrillo, Fernanda Cavallini. "Padronização do alergoteste da tuberculina em ovinos (Ovis aries)." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-15062007-165924/.

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A inexistência de padrões nacionais para a realização e interpretação da prova de tuberculina em ovinos motivou o presente trabalho, pois apesar da tuberculose não estar incluída em Plano Nacional de Controle e Erradicação em pequenos ruminantes, estabelece a legislação vigente que é obrigatório o sacrifício de animais com essa zoonose, sendo o diagnóstico firmado nesses animais principalmente através do alergoteste tuberculínico. Assim, esta pesquisa visou além de avaliar reações clínicas provocadas pela resposta imuno-alérgica intradérmica à tuberculina, estabelecer valores de referência para a interpretação da reação em ovinos experimentalmente inoculados com antígenos de cepas padrões de Mycobacterium bovis e Mycobacterium avium. Utilizou-se 30 ovinos, clinicamente sadios, negativos à prova de tuberculina cervical comparativa (TCC), segundo critérios estabelecidos pelo Ministério da Agricultura, Pecuária e Abastecimento (MAPA) através do Plano Nacional de Controle e Erradicação da Brucelose e Tuberculose (PNCEBT) em bovinos e bubalinos, distribuídos por três grupos de 10 animais cada, a saber: A - sensibilizados com M. avium; B - sensibilizados com M. bovis e C (Controle) - que receberam injeção de solução fisiológica. Os ovinos foram monitorados através de exames físicos e complementares semanais. Após 45 dias da sensibilização, realizou-se a prova de TCC com reação medida pela variação da espessura da pele com cutímetro de mola, nos seguintes momentos: antes da aplicação das tuberculinas (PPDs); 12h, 24h, 48h, 72h e 96h após a aplicação das mesmas. Em relação à reação ao PPD bovino, no teste cervical simples, lido às 72 horas (± 6 horas) pós-tuberculinização (p. t.), considerou-se uma reação como positiva, quando o aumento da espessura da pele foi igual ou maior que 2,49 mm; como inconclusiva, com as medidas de aumento entre 1,00 e 2,48 mm, e como reação negativa, aumentos da espessura da pele inferiores a 1,00 mm, sendo estes valores propostos como padrão para o teste intradérmico simples na região cervical. A análise dos resultados da leitura do teste cervical comparativo, realizada às 72 horas (± 6 horas) p. t., permitiu concluir-se que o animal poderá ser considerado com resposta: positiva, quando a reação ao PPD bovino superar aquela ao aviário em pelo menos 2,00 mm; inconclusiva, quando a reação ao PPD bovino for maior que aquela ao aviário, com diferença entre 1,00 e 1,99 mm, e negativa quando a reação bovina for menor que a aviária ou > em até 0,99 mm. Na avaliação histológica das respostas tuberculínicas homólogas, 96 horas após a injeção do PPD, constatou-se a presença de moderado a intenso infiltrado inflamatória, constituído, preferencialmente, por células mononucleares.
The inexistence of national patterns for the realization and interpretation of tuberculin test in sheep motivated this research. Although tuberculosis is not included in the National Plan for the Control and Eradication in small ruminants, the current legislation has made it mandatory the sacrifice of animals with this zoonosis, where diagnosis is confirmed principally by the usage of the tuberculin skin reaction. Therefore, this study evaluated the clinical manifestations induced by the intradermic immune-allergic response to tuberculin, and established the reference values for the interpretation of this reaction in sheep experimentally inoculated with antigens of recognized strains of Mycobacterium bovis and Mycobacterium avium. Thirty healthy sheep negative to the Comparative Cervical Tuberculin Test (CCT) based on criteria established by the Ministério da Agricultura, Pecuária e Abastecimento (MAPA) in the National Plan for the Control and Eradication of Brucellosis and Tuberculosis in cattle and buffalos were used during this experiment. Animals were separated in three groups: A) sensitized with M. avium, n=10; B) sensitized with M. bovis, n=10; and C) control, n=10, which were injected with saline solution. Sheep were monitored by weekly clinical and complementary exams. After 45 days of inoculation the CCT was evaluated by the variation of dermal thickness determined by a pakimeter realized in the following moments: before the administration of tuberculin (PPD); and 12, 48, 72, and 96 hours after administration of inoculation. Relative to the bovine PPD, the simple cervical test, observed at 72 hours (± 6 hours) post-tuberculinization (p.t.) was considered as: positive, when skin fold thickness was equal or greater than 2.49 mm; inconclusive, skin fold thickness between 1 and 2,48 mm; and negative, when thickness was lower than 1 mm; these values being proposed as reference values for the simple intradermic cervical test. Analyses of the results of the comparative cervical tests realized 72 hr (± 6 hr) p.t. concluded that the animal was considered as: positive, when the bovine PPD reaction was greater than that of the avian by at least 2 mm; and negative, when the bovine reaction was less than the avian or > by 0.99 mm. Histological evaluation of the homologous tuberculin response 96 hr after PPD injection, revealed a moderate to intense inflammatory cellular influx, constituted preferentially, of mononuclear cells.
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Corrêa, João Gabriel Zerba. "Estudo da resposta alérgica à tuberculina em caprinos (Capra hircus) experimentalmente sensibilizados, em diferentes regiões corpóreas." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-16122008-152759/.

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Esta pesquisa visou determinar a resposta alérgica à aplicação do PPD bovino, em diferentes regiões da superfície corpórea de caprinos (Cabra hircus). Para tanto, foram utilizados caprinos adultos, clinicamente sadios e sensibilizados previamente com micobactéria bovina (M. bovis AN5). Para avaliar o local de melhor reação, foram usados 20 animais sensibilizados, distribuídos ao acaso, dos quais 14 animais para constituir o grupo experimental, que recebeu o PPD bovino, e seis animais para o grupo controle, que recebeu solução fisiológica, respectivamente em diferentes regiões do corpo. Os caprinos foram monitorados através de exame clínico com leituras da reação ao PPD realizadas nos seguintes momentos: 24h antes, 0h, 24h, 48h, 72h e 96h após a tuberculinização. Os resultados analisados estatisticamente mostraram uma significância para os melhores locais de aplicação, a saber: as regiões abdominal e torácica dorsais e cervical caudal tanto em 24, quanto em 48 horas e 72 horas pós-tuberculinização. A prega da cauda apresentou resultados menos evidentes que nos mencionados momentos, tendo as regiões torácica e a abdominal ventrais os resultados com menor magnitude de reação.
This study aimed to determine the allergic response to the application of PPD cattle in different regions of the body surface of goats (Goat hircus). For both, were used adult goats, clinically healthy and aware beforehand with bovine mycobacteria (M. bovis AN5). To assess the place of better reaction, 20 animals were used aware, distributed at random, including 14 animals to be the experimental group, which received the PPD veal, and six animal control to group that received saline, respectively in different regions of the body. The goats were monitored by clinical examination with readings of the reaction to the PPD conducted in the following times: 24 hours before, 0h, 24h, 48h, 72h and 96h after tuberculinization. The results showed a statistically analysed significance to the best sites of application, namely: the abdominal and chest regions dorsal and cervical flow in both 24, as in 48 hours and 72 hours after tuberculinization. The results showed the tail fold less evident in the mentioned moments, and the regions thoracic and abdominal ventral results with smaller magnitude of reaction.
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Jukanti, Aravind Kumar. "Molecular and Biochemical Characterization of Wheat (Triticum aestivum. L) Polyphenol Oxidases (PPOs)." Thesis, Montana State University, 2005. http://etd.lib.montana.edu/etd/2005/jukanti/JukantiA1205.pdf.

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Polyphenol oxidases (PPOs) from several plant species, including wheat, have been implicated in the undesirable brown discoloration of food products. Wheat (Triticum aestivum L.) represents an interesting system to advance our understanding of plant PPO function for two important reasons, namely (1) the large size an complexity of its (allohexaploid) genome, and (2) its economic importance. Prior to this study, the molecular and biochemical properties of wheat PPOs were largely unknown. To remedy this situation, we have performed several BLAST searches of expressed sequence tag (EST) databases, using a known wheat PPO sequence as a search tool. This study suggested the presence of at least six PPO genes in hexaploid wheat, falling into two different phylogenetic clusters of three genes each. Presence of a wheat PPO multigene family was confirmed by Southern blotting. A combination of biochemical (enzyme purification and mass spectrometric analysis) and molecular (Northern) approaches confirmed that members of one cluster are not expressed in the developing kernels and senescing flag leaves, while regulation of one or several members of the other gene cluster controls PPO activity in these tissues. Our data, including immunoblotting and enzyme activity studies, further indicated that wheat PPOs are synthesized as inactive precursor (early kernel development) which are proteolytically processed and activated as the kernels mature. Activation of PPO precursor proteins was also demonstrated in vitro, in presence of purified trypsin. In these experiments, PPO activity increased during the first four hours and remained stable thereafter, indicating that the protein domains responsible for catalytic activity are quite stable. Research performed as a part of this dissertation has also demonstrated that wheat PPO activity is influenced by strong anionic detergents such as SDS and N-lauroylsarcosine. The corresponding experiments indicated that these detergents influenced both enzyme extraction and activity, at least in high-PPO wheat varieties. This work also has practical aspects, making PPO assays (as used by breeders for germplasm screening) more robust. In conclusion, as a result of this dissertation, wheat PPOs have emerged as a fascinating example of a plant multigene family with complex transcriptional and posttranscriptional regulation.
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Alfaro, Jara Christian Eugenio. "Contribución al conocimiento de la expresión fenotípica de variantes alélicas para los genes mayores Ppd-A1 y Ppd-B1 en trigo duro." Doctoral thesis, Universitat de Lleida, 2014. http://hdl.handle.net/10803/285578.

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L’objectiu d’aquesta Tesi Doctoral va ser estudiar l’efecte dels gens Ppd-1 sobre la fenologia i els components del rendiment en blat dur. Es va treballar amb una col•lecció de línies amb diverses combinacions al•lèliques per a Ppd-A1 i Ppd-B1, avaluades en quatre localitats a Espanya i Mèxic durant els anys 2007 i 2008. Els resultats mostren que la temperatura i el fotoperíode van distingir les localitats estudiades. Els gens Ppd-1 van explicar gran part de la variabilitat genètica del període sembra-antesi i l’expressió de Ppd-A1a va augmentar quan el fotoperíode mig fins a floració va ser inferior a 12 h. Els al•lels que confereixen insensibilitat al fotoperíode es van classificar com GS-100>GS- 105>Ppd-B1a segons la potència del seu efecte sobre la fenologia. Els genotips portadors de l’al•lel Ppd-A1b van rendir menys en tots els ambients degut a un menor número d’espigues/m2 i menor pes del gra. Els efectes compensatoris entre components del rendiment van ser menors en ambients favorables.
El objetivo de esta Tesis Doctoral fue estudiar el efecto de los genes Ppd-1 sobre la fenología y los componentes del rendimiento en trigo duro. Se trabajó con una colección de líneas con diversas combinaciones alélicas para Ppd-A1 y Ppd-B1, evaluadas en cuatro localidades en España y México durante los años 2007 y 2008. Los resultados muestran que la temperatura y el fotoperíodo distinguieron las localidades estudiadas. Los genes Ppd-1 explicaron gran parte de la variabilidad genética del período siembra-antesis y la expresión de Ppd-A1a aumentó cuando el fotoperíodo medio hasta floración fue inferior a 12 h. Los alelos que confieren insensibilidad al fotoperíodo se clasificaron como GS-100>GS-105>Ppd-B1a según la potencia de su efecto sobre la fenología. Los genotipos portadores del alelo Ppd-A1b rindieron menos en todos los ambientes, debido al menor número de espigas/m2 y menor peso del grano. Los efectos compensatorios entre componentes del rendimiento fueron menores en ambientes favorables.
The aim of this thesis was to study the effect of Ppd-1 genes on the phenology and yield components of durum wheat. A set of lines carrying different allelic combinations at Ppd-A1 and Ppd-B1 loci were tested in four sites (two in Spain and two in Mexico) during 2007 and 2008. The results showed that meteorological traits mostly distinguishing between sites were temperature and photoperiod. The Ppd-1 genes explained much of the genetic variability of sowing-anthesis period. The expression of Ppd-A1a increased when the average photoperiod until anthesis was lower than 12 h. According to its effect on phenology alleles conferring photoperiod insensitivity were classified as GS-100> GS-105> Ppd-B1a. Genotypes carrying the allele Ppd-A1b resulted consistently in the lowest yields due to their few number of spikes per m2 and light grains. Compensatory effects between yield components were lower under favorable environments.
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Wallin, Rebecca, and Kia Pitkämäki. "Mödrars upplevelser av att drabbas av postpartumdepression." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-295333.

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Bakgrund: Postpartumdepression (PPD) drabbar mellan 8-15% av alla kvinnor som föder barn och innebär stora påfrestningar för både modern, partnern och spädbarnet. Utvecklandet av PPD har multifaktoriella orsaker som tidigare psykiatrisk sjukdom, dåligt parförhållande och brist på socialt stöd. Syfte: Studiens syfte var att undersöka kvinnors upplevelser av postpartumdepression. Metod: Studien är en litteraturöversikt där vetenskapliga artiklar motsvarande studiens syfte granskades. Samtliga artiklar hade kvalitativ ansats och söktes i databaserna Cinahl och Pubmed. Resultat: Studiens resultat indelades i tre övergripande teman: moderskap, diagnostisering - samt stöd. Kvinnor som drabbas av PPD uppfattar sig vara misslyckade mödrar samt upplever känslor av hopplöshet och utmattning. Stigmatiseringen kring PPD samt att bli diagnostiserad med psykiatrisk sjukdom, och rädslan av att bli uppfattad som en otillräcklig mor, leder till motvilja att uppsöka vård. Vårdpersonalen uppfattas ofta normalisera kvinnornas depressionssymptom vilket leder till att dessa kvinnor tappar förtroende för vården och inte känner sig sedda eller tagna på allvar. Partnerns och den närmaste omgivningens stöd spelar en betydande roll för att identifiera symptom, söka hjälp och tillfriskna. Slutsats: PPD upplevs av drabbade kvinnor både som ett personligt och socialt stigma, där den egna förmågan till moderskap och lämplighet ifrågasätts. Resultaten indikerar behov av förbättrat bemötande från vården, samt nytänkande inom tillgänglighet och prevention.
Background: Postpartum depression (PPD) affects between 8-15% of all women who give birth to children and poses major new challenges for the mother, partner and baby. The causes behind the development of postpartum depression are multifactorial; a previous psychiatric illness, poor partner relationship and a lack of social support. Aim: The aim of the study was to explore women's experiences of postpartum depression. Method: The study is a literature review in which scientific papers corresponding to the study's aim were reviewed. All reviewed articles had a qualitative approach and was searched in the databases CINAHL and Pubmed. Results: The results of the study were divided into three overarching themes: maternity, diagnosis and support. Women who suffer from PPD perceive themselves to be a failure as mothers and experience feelings of hopelessness and exhaustion. The stigma surrounding PPD and beeing diagnosed with a mental illness, as well as the fear of being perceived as an inadequate mother, are leading to reluctance to seek care. Health care workers are often perceived to normalize women's depressive symptoms which leads to that these women lose trust in the health care system and do not feel they are seen or taken seriously. Support from partner and the immediate surrounding plays a significant role in identifying symptoms, helpseeking and the process of recovery. Conclusion: PPD was experienced by the affected women as both a personal and a social stigma, where their ability to motherhood and suitability was questioned. The results indicate the need for improved treatment of health care, as well as innovation in availability and prevention.
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Books on the topic "PPod"

1

Koleva, Khristina. PPO i preustroĭstvoto. Kŭrdzhali: [s.n.], 1987.

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G, Hillman David, and Garland H. Randall, eds. The PPO handbook. Rockville, Md: Aspen Systems Corp., 1985.

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Jukanti, Aravind. Polyphenol Oxidases (PPOs) in Plants. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2.

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PPD, productive program development. Amherst, Mass: Human Resource Development Press, 1985.

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Evaluation report on PPWD project (1st phase). Dhaka: Evaluation Unit, Family Planning Association of Bangladesh, 1985.

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Cyra, Adam. Spadochroniarz "Urban": Ppor. Stefan Jasieński 1914-1945. Oświęcim: Państwowe Muzeum Auschwitz-Birkenau, 2005.

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Modŏn kŏl, modŏn ppoi ŭi yŏnae wa sarang. Sŏul-si: Essay, 2012.

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Koleva, Khristina. PPO--garant na samoupravlenieto na kolektiva. Sofii͡a︡: Druzhestvo za razprostranenie na nauchni znanii͡a︡ "Georgi Kirkov," Republikanski sŭvet, 1988.

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Rosa, Eugenio. Dois anos de governo PS/PPD. Lisboa: Edicoes Uno de Outubro, 1985.

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Kranz, Karl C. Chiropractic and the HMO-PPO challenge. Washington, D.C: International Chiropractors Association, 1988.

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Book chapters on the topic "PPod"

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Bowers, Shawn, Timothy McPhillips, Sean Riddle, Manish Kumar Anand, and Bertram Ludäscher. "Kepler/pPOD: Scientific Workflow and Provenance Support for Assembling the Tree of Life." In Lecture Notes in Computer Science, 70–77. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-89965-5_9.

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Braun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "PPCD." In Encyclopedia of Molecular Mechanisms of Disease, 1708. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7926.

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Gooch, Jan W. "PPOX." In Encyclopedic Dictionary of Polymers, 583. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9359.

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Gooch, Jan W. "PPO." In Encyclopedic Dictionary of Polymers, 583. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9358.

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Jukanti, Aravind. "Introduction." In Polyphenol Oxidases (PPOs) in Plants, 1–9. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2_1.

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Jukanti, Aravind. "Distribution, Localization, and Structure of Plant Polyphenol Oxidases (PPOs)." In Polyphenol Oxidases (PPOs) in Plants, 11–32. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2_2.

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Jukanti, Aravind. "Physicochemical Properties of Polyphenol Oxidases." In Polyphenol Oxidases (PPOs) in Plants, 33–56. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2_3.

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Jukanti, Aravind. "Reaction Features of Polyphenol Oxidases." In Polyphenol Oxidases (PPOs) in Plants, 57–72. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2_4.

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Jukanti, Aravind. "Function(s)/Role(s) of Polyphenol Oxidases." In Polyphenol Oxidases (PPOs) in Plants, 73–92. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2_5.

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Jukanti, Aravind. "Polyphenol Oxidase(s): Importance in Food Industry." In Polyphenol Oxidases (PPOs) in Plants, 93–106. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5747-2_6.

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Conference papers on the topic "PPod"

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Bagdonavičienė, Aistė, Aušra Brazaitytė, Julė Jankauskienė, and Pavelas Duchovskis. "THE EFFECT OF PHOTOSYNTHETIC PHOTON FLUX DENSITY ON CUCUMBER AND TOMATO TRANSPLANTS ASSIMILATIVE INDICES." In Rural Development 2015. Aleksandras Stulginskis University, 2015. http://dx.doi.org/10.15544/rd.2015.030.

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The objective of our studies was to evaluate the assimilative indices of cucumber (‘Pasalimo F1’) and tomato (‘Marissa F1’) transplants, cultivated under various photosynthetic photon flux densities (PPFD) were provided by light-emitting diodes (LEDs). Experiment was performed in phytotron complex of Institute of Horticulture, LRCAF. A system of high-power, solid-state lighting modules with 92 % 638 nm (red) + 665 nm (red) + 731 nm (far red) and 8 % 447 nm (blue) was used in the experiments. The generated PPFD of each type of five solid-state modules was ~200 and ~400 μmol m-2 s-1. Our experiment revealed that increased net assimilation rate (NAR) depended on increased PPFD of cucumber and tomato hybrid. 400 μmol m-2 s-1 LED illumination had positive effect on relative growth rate (RGR). Cucumbers which were grown under 200 μmol m-2 s-1 had bigger leaf area ratio (LAR) and specific leaf area (SLA), their development has been bigger as compared to higher 400 μmol m-2 s-1 PPFD. High PPFD LED illumination had positive effect on leaf weight ratio (LWR), shoot root ratio (SRR) and tomato transplants development. These studies with various photosynthetic photon flux densities (PPFD) and LEDs light should be continued throughout plant vegetation.
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Sacco, Owen, and John G. Breslin. "PPO & PPM 2.0." In the 8th International Conference. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2362499.2362511.

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Mehta, Ruta. "Constant rank bimatrix games are PPAD-hard." In STOC '14: Symposium on Theory of Computing. New York, NY, USA: ACM, 2014. http://dx.doi.org/10.1145/2591796.2591835.

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"CMOS-circuit Protection Against PPID For Yield Enhancement." In 2nd International Symposium on Plasma Process-Induced Damage. IEEE, 1997. http://dx.doi.org/10.1109/ppid.1997.596730.

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Jin, Jianguo. "PPOS SYSTEM: A System of Partitioning Polygonal Objects." In 2009 First International Conference on Information Science and Engineering. IEEE, 2009. http://dx.doi.org/10.1109/icise.2009.840.

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Fearnley, John, Paul W. Goldberg, Alexandros Hollender, and Rahul Savani. "The complexity of gradient descent: CLS = PPAD ∩ PLS." In STOC '21: 53rd Annual ACM SIGACT Symposium on Theory of Computing. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3406325.3451052.

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Kondic Špika, Ankica, Dragana Trkulja, Sanja Mikic, and Ljiljana Brbaklic. "COMPARISON OF AGRONOMICAL PERFORMANCE OF SERBIAN WHEAT CULTIVARS AND NILs WITH DIFFERENT PPD ALLELES." In XXVI savetovanje o biotehnologiji sa međunarodnim učešćem. Agronomski fakultet Univerziteta u Kragujevcu, 2021. http://dx.doi.org/10.46793/sbt26.025ks.

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Photoperiod response (Ppd) genes are very important for adaptation of wheat to different agro-climatic conditions, but also have influence on crop yield. The aim of this study was to compare agronomic traits of 10 Serbian wheat cultivars and 54 NILs of cv. Paragon with single, double and triple doses of Ppd-1 alleles. The results showed that the NILs with introgressed single early Ppd-1 alleles (Set 2), as well as the NILs with introgressed Ppd-1 null alleles, knock-outs and late alleles (Set 4) had significantly longer stems and spikes then Serbian cultivars (Set 1). The lines with introgressed double early Ppd-1 alleles (Set 3) were very similar to the Serbian cultivars. Some promising lines with good potential for breeding programs were identified
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Murase, Takuro. "Development of PPD: characterization & simulation." In International Workshop on New Photon Detectors. Trieste, Italy: Sissa Medialab, 2010. http://dx.doi.org/10.22323/1.090.0003.

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Jain, Moksh, and S. Sowmya Kamath. "Improving Convergence in IRGAN with PPO." In CoDS COMAD 2020: 7th ACM IKDD CoDS and 25th COMAD. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3371158.3371209.

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Zhang, Hongli, Jiantao Shi, Lin Ye, and Xiaojiang Du. "PPBD: A piracy preventing system for BT DHT networks." In IEEE INFOCOM 2013 - IEEE Conference on Computer Communications. IEEE, 2013. http://dx.doi.org/10.1109/infcom.2013.6566979.

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Reports on the topic "PPod"

1

Pietrass, Tanja. MPA CINT PPD-4 Search. Office of Scientific and Technical Information (OSTI), July 2019. http://dx.doi.org/10.2172/1544655.

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Calhoun, Norann. NCS- Controls and PPD Response. Office of Scientific and Technical Information (OSTI), December 2020. http://dx.doi.org/10.2172/1735886.

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Fultonberg, D. N. Accelerator Production of Tritium PPO Management Plan. Office of Scientific and Technical Information (OSTI), March 1998. http://dx.doi.org/10.2172/763156.

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Walsh, Maria L. Report on Pollution Prevention Opportunity Assessment (PPOA) of SNL Print Shop (Org. 13418). Office of Scientific and Technical Information (OSTI), October 1994. http://dx.doi.org/10.2172/1455352.

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Gruber, Jonathan. The Effect of Price Shopping in Medical Markets: Hospital Responses to PPOs in California. Cambridge, MA: National Bureau of Economic Research, October 1992. http://dx.doi.org/10.3386/w4190.

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Zaczek, M. Stress Analysis of the D-Zero Solenoid Magnet Lifting Fixture PPD Fixture #102. Office of Scientific and Technical Information (OSTI), December 1997. http://dx.doi.org/10.2172/1032126.

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Humphrey, Brandt M., and Aubrey Higginbotham. Environmental Assessment: Lease with Omaha Public Power District (PPD) to Support New United States Strategic Command (USSTRATCOM) Facility and Existing Base Load. Fort Belvoir, VA: Defense Technical Information Center, February 2013. http://dx.doi.org/10.21236/ada614638.

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2020 Annual Procurement Report. Asian Development Bank, April 2021. http://dx.doi.org/10.22617/spr210082-2.

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This report provides an overview of procurement activities supported by the Procurement, Portfolio, and Financial Management Department (PPFD) of the Asian Development Bank (ADB) in 2020. It covers key areas where PPFD provides policy, guidance, and support to ADB developing member countries to create procurement solutions that help deliver value for money and quality outcomes across Asia and the Pacific. The report includes a reflection on achievements, while also presenting a forward-looking perspective on priorities and focus areas for PPFD and ADB’s procurement in the years to come.
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