Academic literature on the topic 'Pre-Analytical requirements'

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Journal articles on the topic "Pre-Analytical requirements"

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Vermeersch, Pieter, Glynis Frans, Alexander von Meyer, Seán Costelloe, Giuseppe Lippi, and Ana-Maria Simundic. "How to meet ISO15189:2012 pre-analytical requirements in clinical laboratories? A consensus document by the EFLM WG-PRE." Clinical Chemistry and Laboratory Medicine (CCLM) 59, no. 6 (2021): 1047–61. http://dx.doi.org/10.1515/cclm-2020-1859.

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Abstract The International Organization for Standardization (ISO) 15189:2012 standard aims to improve quality in medical laboratories through standardization of all key elements in the total testing process, including the pre-analytical phase. It is hence essential that accreditation bodies, assessing laboratories against ISO15189:2012, pay sufficient attention to auditing pre-analytical activities. However, there are significant differences in how technical auditors interpret the pre-analytical requirements described in ISO15189:2012. In this consensus document, the European Federation of Cli
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Dagher, Georges, Karl-Friedrich Becker, Serena Bonin, et al. "Pre-analytical processes in medical diagnostics: New regulatory requirements and standards." New Biotechnology 52 (September 2019): 121–25. http://dx.doi.org/10.1016/j.nbt.2019.05.002.

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Krčmová, Lenka Kujovská, Bohuslav Melichar, and František Švec. "Chromatographic methods development for clinical practice: requirements and limitations." Clinical Chemistry and Laboratory Medicine (CCLM) 58, no. 11 (2020): 1785–93. http://dx.doi.org/10.1515/cclm-2020-0517.

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AbstractDevelopment of a chromatographic method in bioanalysis is a challenging and complex procedure with many pitfalls and often unexpected reversals that can require several months to accomplish. Even an experienced analytical team must contend many limitations mainly in connection with the strict requirements imposed on current clinical research. These restrictions typically persist throughout the whole development process, from clinical trial assignment, across optimization of extraction of biological materials and chromatographic separation, to validation and data interpretation. This pa
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Pietruczuk, Mirosława, Łukasz Kraszula, Anna Jasińska, Piotr Kuna, and Makandjou-Ola Eusebio. "The usefulness of quality indicators of preanalitical phase in medical labs, according to the Quality standards requirements, ISO 15189:2013 and WG-LEPS recommendation, Jan 2017." Diagnostyka Laboratoryjna 55, no. 2 (2019): 113–20. http://dx.doi.org/10.5604/01.3001.0013.7453.

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This paper presents the usefulness of pre-analytical process in medical diagnostic laboratories, recommended by WG-LEPS, according to departmental requirements and ISO 15189, with regard to clinical hospital laboratory. It is known that the pre-analytical process generates over 70% of all laboratory errors. The tested materials are laboratory test referrals data for a period of one year (2017), mainly from the Laboratory Information Management System. The study includes the mean annual pre-laboratory error rates. The results showed low error rates in the areas related to the laboratory testing
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Kristoffersen, Ann Helen, Anne V. Stavelin, Eva Ajzner, et al. "Pre-analytical practices for routine coagulation tests in European laboratories. A collaborative study from the European Organisation for External Quality Assurance Providers in Laboratory Medicine (EQALM)." Clinical Chemistry and Laboratory Medicine (CCLM) 57, no. 10 (2019): 1511–21. http://dx.doi.org/10.1515/cclm-2019-0214.

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Abstract Background Correct handling and storage of blood samples for coagulation tests are important to assure correct diagnosis and monitoring. The aim of this study was to assess the pre-analytical practices for routine coagulation testing in European laboratories. Methods In 2013–2014, European laboratories were invited to fill in a questionnaire addressing pre-analytical requirements regarding tube fill volume, citrate concentration, sample stability, centrifugation and storage conditions for routine coagulation testing (activated partial thromboplastin time [APTT], prothrombin time in se
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Kutlija, Nevena. "Hemolysis - a constant source of error in laboratory diagnostics // Hemoliza – stalni izvor greške u laboratorijskoj dijagnostici." SESTRINSKI ŽURNAL 4, no. 1 (2017): 55. http://dx.doi.org/10.7251/sez0117055k.

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The aim of this paper is to point out the importance of proper pre-analytical preparation of the sample in order to reduce the number of errors in the laboratory with a special emphasis on hemolysis. In recent years, the lab has become more efficient in terms of faster results, more precise, faster and more precise controls, all due to automation, but it needs to be cautious as errors continue to occur. The largest share of errors occurs in the pre-analytic and post-analytical phase. The erythrocyte hemolysis in vivo or in vitro is one of the most significant errors in the preanalytic phaseThi
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Snyder, James W. "Blood Cultures: the Importance of Meeting Pre-Analytical Requirements in Reducing Contamination, Optimizing Sensitivity of Detection, and Clinical Relevance." Clinical Microbiology Newsletter 37, no. 7 (2015): 53–57. http://dx.doi.org/10.1016/j.clinmicnews.2015.03.001.

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Konstandatos, Otto. "Fair-value analytical valuation of reset executive stock options consistent with IFRS9 requirements." Annals of Actuarial Science 14, no. 1 (2020): 188–218. http://dx.doi.org/10.1017/s1748499519000125.

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AbstractExecutive stock options (ESOs) are widely used to reward employees and represent major items of corporate liability. The International Accounting Standards Board IFRS9 financial reporting standard which came into full effect on 1-Jan 2018, along with its Australian implementation AASB9, requires public corporations to report their fair-value cost in financial statements. Reset ESOs are typically issued to re-incentivise employees by allowing the option to be cancelled and re-issued with a lower exercise price or later maturity. We produce a novel analytical Reset ESO valuation consiste
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Athanasiadou, Zoi S., Antonia Mourtzikou, Marilena Stamouli, and Petros Karkalousos. "Quality Indicators for the Performance Evaluation at a Biochemistry Laboratory." International Journal of Reliable and Quality E-Healthcare 9, no. 2 (2020): 18–33. http://dx.doi.org/10.4018/ijrqeh.2020040102.

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The use of quality indicators and risk evaluation are valuable tools for maintaining the quality of laboratory tests. There are both requirements of ISO 15189: 2012 and are usually based on common statistical and empirical data. The purpose of the present study was the quality quantification and risk evaluation through the collection, study, and analysis of quality indicators covering the pre-analytical, analytical, and post-analytical phases of the laboratory testing process. Statistical data was collected for the period from 1/12/2017 to 28/2/2018, using the LIS of Biochemical Laboratory. QI
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Knight, D., R. Singer, J. M. White, and C. G. Fraser. "Laboratory evaluation of the Du Pont "Dimension Clinical Chemistry System"." Clinical Chemistry 34, no. 9 (1988): 1899–903. http://dx.doi.org/10.1093/clinchem/34.9.1899.

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Abstract We evaluated the analytical performance of the Du Pont Dimension Clinical Chemistry System to assess its suitability as a replacement for the Du Pont aca III, currently routinely used for analysis of pediatric, high-risk, and emergency specimens. Twenty-six analyses were studied. These generally fulfilled pre-set analytical goals for precision based on biological variation or "state of the art." Significant economies were achieved and we found the Dimension to be reliable, easy to operate, and simple to maintain. It also fulfilled safety requirements for analysis of specimens of high
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Dissertations / Theses on the topic "Pre-Analytical requirements"

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Lovergne, Lila. "Diagnostic pré-symptomatique rapide du sepsis par spectroscopie vibrationnelle." Thesis, Reims, 2018. http://www.theses.fr/2018REIMS026.

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Le sepsis est une dérégulation de la réponse de l’hôte à une infection, associé à un dysfonctionnement des organes engageant le pronostic vital du patient. Plus de 30 millions de cas et 5 millions de décès sont estimés par an dans le monde. Le diagnostic du sepsis est basé sur des signes cliniques non spécifiques et la longue procédure d’identification des pathogènes responsables de l’infection. L’objectif de cette étude est de développer et d’évaluer le potentiel de la spectroscopie vibrationnelle appliquée au sérum pour améliorer le diagnostic du sepsis. Les défis inhérents à la nature de l’
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Placido, Rui. "Estimating measurement uncertainty in the medical laboratory." Thesis, Cranfield University, 2016. http://dspace.lib.cranfield.ac.uk/handle/1826/11258.

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Medical Laboratories Accreditation is covered by ISO 15189:2012 - Medical Laboratories — Requirements for Quality and Competence. In Portugal, accreditation processes are held under the auspices of the Portuguese Accreditation Institute (IPAC), which applies the Portuguese edition (NP EN ISO 15189:2014). Accordingly, Medical Laboratories accreditation processes now require the estimate of measurement uncertainty (MU) associated to the results. The Guide to the Expression of Uncertainty in Measurement (GUM) describes the calculation of MU, not contemplating the specific aspects of medical labor
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Book chapters on the topic "Pre-Analytical requirements"

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El Messaoudi, Safia, and Alain R. Thierry. "Pre-analytical Requirements for Analyzing Nucleic Acids from Blood." In Advances in Predictive, Preventive and Personalised Medicine. Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9168-7_3.

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Rajendran, Mohan Kumar, Michael Budnitzki, and Meinhard Kuna. "Multi-scale Modeling of Partially Stabilized Zirconia with Applications to TRIP-Matrix Composites." In Austenitic TRIP/TWIP Steels and Steel-Zirconia Composites. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42603-3_21.

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Abstract The understanding of how the microstructure influences the mechanical response is an essential pre-requisite for materials tailored to match specific requirements. The aim of this chapter is to further this understanding in the context of Mg-PSZ-TRIP-steel composites on three different scales using a set of methods ranging from phase-field simulations over micromechanics to continuum constitutive modeling. On the microscale, using a Ginzburg-Landau type phase-field model the effects of cooling- and stress-induced martensitic phase transformation in MgO-PSZ is clearly distinguished. Additionally with this method the role of energy barrier in variant selection and the effect of residual stress contributing to the stability of the tetragonal phase are also investigated. On the mesomechanical scale, an analytical 2D model for the martensitic phase transformation and self-accommodation of inclusions within linear elastic materials has been successfully developed. The influences of particle size and geometry, chemical driving force, temperature and surface energy on the $$t \rightarrow m$$ t → m transformation are investigated in a thermostatic approach. On the continuum scale, a continuum material model for transformation plasticity in partially stabilized zirconia ceramics has been developed. Nonlinear hardening behavior, hysteresis and monoclinic phase fraction during a temperature cycle are analyzed. Finally, The mechanical properties of a TRIP steel matrix reinforced by ZrO$$_2$$ 2 particles are analyzed on representative volume elements. Here the mechanical properties of the composite as function of volume fraction of both constituents and the strength of the interface are studied.
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Wiwanitkit, Viroj. "Overview of Requirements and Future Perspectives on Current Laboratory Information Management Systems." In Advances in Healthcare Information Systems and Administration. IGI Global, 2015. http://dx.doi.org/10.4018/978-1-4666-6320-6.ch004.

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The chapter argues that a Laboratory Information Management System (LIMS) is the application of computational technology in laboratory medicine. This is an advanced technology that can support the general work in medical laboratories. The LIMS can also be useful in all steps of the laboratory cycle (pre-, intra-, and post-analytical phases). There are many LIMSs at present, and those LIMSs are used worldwide. The present concern is on the standardization of the existing system. In this context, international collaboration to set the standards is required. In addition, the multidisciplinary approach to add up the advantage and application of the technology is promising. With the more advanced computational and wireless information technology, the next step of LIMS will be big wireless LIMS networks that extend from medical laboratories and wards within the hospital to outside units as well as patient homes. The point-of-care LIMSs are the actual future perspectives.
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Woolrych, Alan, and Mark Hindmarch. "Understanding and Improving Usability Inspection Methods." In Encyclopedia of Human Computer Interaction. IGI Global, 2006. http://dx.doi.org/10.4018/978-1-59140-562-7.ch096.

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Usability inspection method (UIM) is the term used for a variety of analytical methods designed to “find” usability problems in an interface design. The basic principle involves analysts inspecting the interface against a set of pre-determined rules, standards or requirements. Analysts inspect the interface and predict potential usability problems based on breaches of these rules. None of the UIMs currently in use are capable of detecting all of the problems associated with an interface. After describing some of the UIMs in use, this article will look at the authors’ work on improving these methods by focusing on the resources analysts bring to an inspection.
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Conference papers on the topic "Pre-Analytical requirements"

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Provasi, Rodrigo, Leonardo Riccioppo Garcez, Christiano Odir Cardoso Meirelles, Clovis de Arruda Martins, Andre Freitas Barbosa, and Olaf Oswaldo Otte Filho. "An Integrated Environment for Design and Analysis of Umbilical Cables." In ASME 2017 36th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/omae2017-61857.

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The design of an umbilical cable begins with the definition of the operational functions it must implement and the environmental conditions to that it will be subjected to. Those functions suggest the components that it must have, usually chosen from a pre-defined set. Also, structural elements must be added, based on project and manufacture requirements, so the cable can withstand the environmental conditions of use. All the components must be geometrically arranged and the cross section of the cable must be defined, usually with the help of CAD software. But the structural behavior of the de
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Botros, K. K. "Single vs. Dual Recycle System Requirements in the Design of High Pressure Ratio, Low Inertia Centrifugal Compressor Stations." In ASME 2011 Turbo Expo: Turbine Technical Conference and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/gt2011-45002.

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Compression systems are designed and operated in a manner to eliminate or minimize the potential for surge, which is a dynamic instability that is very detrimental to the integrity of the compressor unit. Compressor surge can occur when compressors are subjected to rapid transients such as those occurring following an emergency shutdown (ESD) or a power failure, which in turn, requires fast reaction. To prevent this from occurring, compressor stations are designed with single or dual recycle systems with recycle valves, which are required to open upon ESD. There has been extensive debate and c
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Pal, Sangita, Mousumi Singha, and Sher Singh Meena. "Pre-concentration technique for reduction in “Analytical instrument requirement and analysis”." In DAE SOLID STATE PHYSICS SYMPOSIUM 2017. Author(s), 2018. http://dx.doi.org/10.1063/1.5028779.

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Wu, Tsu-Te, Paul S. Blanton, and Kurt R. Eberl. "Dynamic Analysis of the Bulk Tritium Shipping Package Subjected to Closure Torques and Sequential Impacts." In ASME 2007 Pressure Vessels and Piping Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/pvp2007-26294.

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This paper presents a finite-element technique to simulate the structural responses and to evaluate the cumulative damage of a radioactive material packaging requiring bolt closure-tightening torque and subjected to the scenarios of the Hypothetical Accident Conditions (HAC) defined in the Code of Federal Regulations Title 10 part 71 (10CFR71). Existing finite-element methods for modeling closure stresses from bolt pre-load are not readily adaptable to dynamic analyses. The HAC events are required to occur sequentially per 10CFR71 and thus the evaluation of the cumulative damage is desirable.
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Jang, Sungwoo, and Hae-Jin Choi. "Design Methods for Integrated Design of Blast Resistance Panels and Materials." In ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/detc2013-12281.

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Integrated Materials and Products Design (IMPD) differs in the way that materials as well as product layout are designed or optimized in a concurrent manner to meet design requirements. IMPD allows the specific performance required in a product to be achieved by tailoring materials and product, since system performance will not be limited by a pre-chosen material employed in conventional, material-selection-based design. In this study, Blast Resistance Panels (BRPs) with square honeycomb core are designed based on this new design approach to further enhance the performance of BRPs. We employ m
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Zhang, Jiaying, Alexander D. Shaw, Amoozgar Mohammadreza, Michael I. Friswell, and Benjamin K. S. Woods. "Spiral Pulley Negative Stiffness Mechanism for Morphing Aircraft Actuation." In ASME 2018 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/detc2018-85640.

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The energy balancing concept seeks to reduce actuation requirements for a morphing structure by strategically locating negative stiffness devices to tailor the required deployment forces and moments. One such device is the spiral pulley negative stiffness mechanism. This uses a cable connected with a pre-tension spring to covert decreasing spring force into increasing balanced torque. The kinematics of the spiral pulley are firstly developed and its geometry is then optimised by employing an energy conversion efficiency function. The performance of the optimised spiral pulley is then evaluated
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Belanger, Rory, and Derrick Sarafinchan. "Implementation of CSA Z662-15 Annex K Option 2 on a 610mm Liquid Pipeline." In 2016 11th International Pipeline Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/ipc2016-64564.

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For more than two decades, CSA Z662 Annex K has provided a method for developing alternative acceptance criteria for weld flaws in mechanized welded pipelines. Increasingly, over the years, fracture mechanics practitioners have found the method overly conservative and restrictive with respect to brittle fracture criteria when compared to other accepted fracture mechanics-based engineering critical assessment ECA codes and methods. These limitations rendered the CSA Annex K method difficult to implement on pipelines constructed with materials not possessing optimal toughness and in cases requir
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Mogbo, Obuekwe, and Adetayo Atewologun. "Innovative Use of Injectivity Tests as Interference Tests during Field Development: The EGINA Experience." In SPE Nigeria Annual International Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/207181-ms.

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Abstract This paper presents the innovative use of interference tests in the assessment of reservoir connectivity and the field oil production rate during the development phase and prior to the first oil of the EGINA field, which is located in a water depth of 1600 m, deep offshore Niger Delta. The interference test campaign involved 26 pre-first oil wells (13 oil producers and 13 water injectors) to assess and subsequently mitigate reservoir connectivity uncertainties arising from the numerous faults and between the different channels within the complexes. The results proved valuable in confi
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Liszkai, Tama´s R., Matthew Snyder, Steve Fyfitch, Hongqing Xu, and Hasan Charkas. "Application of Aging Management Strategies for Reactor Vessel Internals and Core Support Structures." In ASME 2010 Pressure Vessels and Piping Division/K-PVP Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/pvp2010-26137.

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The Materials Reliability Program (MRP) Reactor Internals Focus Group (RI-FG) developed Pressurized Water Reactor (PWR) Internals Inspection and Evaluation (I&E) Guidelines under the sponsorship of the Electric Power Research Institute (EPRI). The I&E guidelines summarized in MRP-227 [1], provide a generic basis for U.S. utilities to develop their Aging Management Program (AMP) for managing the long-term aging degradation of PWR reactor internals including the existing and extended license periods. A number of internals structural bolts in the Babcock & Wilcox (B&W) design PWRs
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Tosin, Stefano, Jens Friedrichs, Johann Sperling, and Dragan Kožulović. "Aerodynamic Optimization of Turboprop Turbine Blades Using a Response Surface Methodology Based Algorithm." In ASME 2014 4th Joint US-European Fluids Engineering Division Summer Meeting collocated with the ASME 2014 12th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/fedsm2014-21752.

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Turbomachinery blade design improvement and optimization by CFD is a time-consuming engineering challenge. Such an optimization process, which requires advanced numerical simulations, uses a large amount of computational resources to provide the required solutions. This paper presents a turbine blade optimization process which uses an algorithm based on response surface methodology (RSM) to increase the simulation speed. The main idea of RSM is to start with a lower number of sample points to generate an analytical model that describes the relationship between the pre-defined numbers of design
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