Academic literature on the topic 'Pre-clinical imaging'

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Journal articles on the topic "Pre-clinical imaging"

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Drexler, W. "SP-0516: Optical imaging in pre-clinical research." Radiotherapy and Oncology 106 (March 2013): S200. http://dx.doi.org/10.1016/s0167-8140(15)32822-x.

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Hazle, J. "WE-EF-204-01: Pre-Clinical Imaging for Co-Clinical Trials." Medical Physics 42, no. 6Part39 (June 2015): 3680. http://dx.doi.org/10.1118/1.4926004.

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Meikle, Steven, Stefan Eberl, and Hidehiro Iida. "Instrumentation and Methodology for Quantitative Pre-Clinical Imaging Studies." Current Pharmaceutical Design 7, no. 18 (December 1, 2001): 1945–66. http://dx.doi.org/10.2174/1381612013396961.

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Kondrashova, T., D. De Wan, M. U. Briones, and P. Kondrashov. "Integration of ultrasound imaging into pre-clinical dental education." European Journal of Dental Education 21, no. 4 (April 4, 2016): 228–34. http://dx.doi.org/10.1111/eje.12205.

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Madonna, R., C. Cevik, and N. Cocco. "Multimodality imaging for pre-clinical assessment of Fabry's cardiomyopathy." European Heart Journal - Cardiovascular Imaging 15, no. 10 (June 5, 2014): 1094–100. http://dx.doi.org/10.1093/ehjci/jeu080.

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Zöllner, Frank G., Raffi Kalayciyan, Jorge Chacón-Caldera, Fabian Zimmer, and Lothar R. Schad. "Pre-clinical functional Magnetic Resonance Imaging part I: The kidney." Zeitschrift für Medizinische Physik 24, no. 4 (December 2014): 286–306. http://dx.doi.org/10.1016/j.zemedi.2014.05.002.

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Meßner, Nadja M., Frank G. Zöllner, Raffi Kalayciyan, and Lothar R. Schad. "Pre-clinical functional Magnetic Resonance Imaging part II: The heart." Zeitschrift für Medizinische Physik 24, no. 4 (December 2014): 307–22. http://dx.doi.org/10.1016/j.zemedi.2014.06.008.

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Finegan, K., M. Babur, D. Forster, J. O’Connor, C. Tournier, and K. Williams. "A novel pre-clinical model for imaging cancer-associated inflammation." European Journal of Cancer 61 (July 2016): S107. http://dx.doi.org/10.1016/s0959-8049(16)61377-1.

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O'Neill, Karen, Scott K. Lyons, William M. Gallagher, Kathleen M. Curran, and Annette T. Byrne. "Bioluminescent imaging: a critical tool in pre-clinical oncology research." Journal of Pathology 220, no. 3 (October 27, 2009): 317–27. http://dx.doi.org/10.1002/path.2656.

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ÁLVAREZ, F. J., J. BISBE, V. BISBE, and A. DÁVALOS. "MAGNETIC RESONANCE IMAGING FINDINGS IN PRE-CLINICAL CREUTZFELDT-JAKOB DISEASE." International Journal of Neuroscience 115, no. 8 (January 2005): 1219–25. http://dx.doi.org/10.1080/00207450590914491.

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Dissertations / Theses on the topic "Pre-clinical imaging"

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Bianchi, Andrea. "Magnetic resonance imaging techniques for pre-clinical lung imaging." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0060/document.

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Dans ce travail, les s´séquences Imagerie par Résonance Magnétique (IRM) radiales à temps d’écho ultra-court (UTE) sont analysées pour évaluer leur potentiel dans l’étude non-invasive de différents modèles expérimentaux de maladies pulmonaires chez la souris. Chez le petit animal, les séquences radiales UTE peuvent efficacement limiter l’impact négatif sur la qualité de l’image dû au déphasage rapide des spins causé par les nombreuses interfaces air/tissu. En plus, les séquences radiales UTE sont moins sensibles aux artefacts de mouvement par rapport aux séquences Cartésiennes classiques. En c
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Almeida, Gilberto Serrano de. "Pre-clinical imaging evaluation of the PARP inhibitor rucaparib." Thesis, University of Newcastle upon Tyne, 2013. http://hdl.handle.net/10443/2033.

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Poly(ADP-ribose) polymerase 1 (PARP1) is a DNA-binding enzyme involved in DNA repair by the base-excision pathway. The inhibition of PARP1 is being investigated as a cancer treatment. Rucaparib (CO338) is a potent PARP 31 inhibitor currently in Phase II clinical development. In this thesis P in vivo MR Spectroscopy (MRS) and Dynamic Contrast Enhanced (DCE) MRI were used to study acute effects of rucaparib on energy metabolism and tumour vasculature. 1 31 18 18 Ex vivo H and P-MRS, and in vivo [ F]FLT and [ F]FDG-PET, were used to study effects of treatment with rucaparib on tumour metabolism a
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Namati, Eman, and eman@namati com. "Pre-Clinical Multi-Modal Imaging for Assessment of Pulmonary Structure, Function and Pathology." Flinders University. Computer Science, Engineering and Mathematics, 2008. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20081013.044657.

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In this thesis, we describe several imaging techniques specifically designed and developed for the assessment of pulmonary structure, function and pathology. We then describe the application of this technology within appropriate biological systems, including the identification, tracking and assessment of lung tumors in a mouse model of lung cancer. The design and development of a Large Image Microscope Array (LIMA), an integrated whole organ serial sectioning and imaging system, is described with emphasis on whole lung tissue. This system provides a means for acquiring 3D pathology of fixed w
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Assadian, Sarah. "Rodent FDG-PET imaging for the pre-clinical assessment of novel glioma therapies." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=101836.

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The rapid discovery of novel therapeutic agents, targeting the specific mechanism of cancer progression, invasion and angiogenesis, necessitates the development and validation of efficient techniques to assess the therapeutic efficacy of these drugs in vivo. Recently the development of dedicated PET scanners for the imaging of small animals, such as the microPET system (CTI Concorde R4), has allowed for the high-resolution functional and molecular imaging of murine and rodent models of disease. This study, investigates the ability of microPET imaging, using the 18F labelled 2-fluoro-2-deoxyglu
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Ambrosini, Valentina <1975&gt. "Pre-clinical imaging: small animal pet and CT applications in pneumology, oncology and cardiology." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2008. http://amsdottorato.unibo.it/1087/.

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Chen, Liu Qi. "Development and Application of AcidoCEST MRI for Evaluating Tumor Acidosis in Pre-Clinical Cancer Models." Diss., The University of Arizona, 2014. http://hdl.handle.net/10150/323450.

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Tumor acidosis is an important biomarker in cancer. We have developed a noninvasive imaging method, termed acidosis Chemical Exchange Saturation Transfer (acidoCEST) MRI to measure extracellular pH (pHe) in the tumor microenvironment. Chapter 1 introduces the importance of measuring tumor acidosis and presents various imaging modalities and their shortcoming to measure pHe. Chapter 2 describes the optimization of acidoCEST MRI for in vivo pHe measurement. The acidoCEST MRI protocol consists of a CEST-FISP acquisition and Lorentzian line shape fittings. We determined the optimal saturation time
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Jones, Bernard Lee. "Development of dosimetry and imaging techniques for pre-clinical studies of gold nanoparticle-aided radiation therapy." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/43727.

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Cancer is one of the leading causes of death worldwide, and affects roughly 1.5 million new people in the United States every year. One of the leading tools in the detection and treatment of cancer is radiation. Tumors can be detected and identified using CT or PET scans, and can then be treated with external beam radiotherapy or brachytherapy. By taking advantage of the physical properties of gold and the biological properties of nanoparticles, gold nanoparticles (GNPs) can be used to improve both cancer radiotherapy and imaging. By infusing a tumor with GNPs, either using passive extravasati
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Landuyt, Willy. "Intra-tumoural blood vessels and hypoxia: targets for treatment and imaging to improve anti-cancer therapies pre-clinical investigations /." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 2002. http://arno.unimaas.nl/show.cgi?fid=7247.

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Onthank, David C. "Prediction of "First Dose in Human" for radiopharmaceuticals/imaging agents based on allometric scaling of pharmacokinetics in pre-clinical animal models." Link to electronic dissertation, 2005. http://www.wpi.edu/Pubs/ETD/Available/etd-011006-132234/.

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Adcock, Jane Elizabeth St Vincent's Clinical School UNSW. "The reliability and clinical validity of functional magnetic resonance imaging in the assessment of language in pre-surgical patients with temporal lobe epilepsy." Awarded by:University of New South Wales. St Vincent's Clinical School, 2005. http://handle.unsw.edu.au/1959.4/22484.

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Defining language lateralisation is important to minimise morbidity in patients treated surgically for temporal lobe epilepsy (TLE). Functional magnetic resonance imaging (fMRI) offers a promising, non-invasive, alternative strategy to the Wada test. Here, fMRI has been used to study healthy controls and patients with TLE in order (i) to define language-related activation patterns and their reproducibility; (ii) to compare lateralisation determined by fMRI with that from the Wada test; and (iii) to explore the usefulness of multiple fMRI language paradigms. 18 healthy controls (12 right-handed
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Books on the topic "Pre-clinical imaging"

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Najarian, Kayvan. Biomedical Signal and Image Processing. Boca Raton: Taylor & Francis, 2012.

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Nixdorff, Uwe, Stephan Achenbach, Frank Bengel, Pompillio Faggiano, Sara Fernández, Christian Heiss, Thomas Mengden, et al. Imaging in cardiovascular prevention. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0006.

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Imaging tools in preventive cardiology can be divided into imaging modalities to assess pre-clinical and clinical atherosclerosis and functional assessments of vascular function or vascular inflammation. To calculate the likelihood of pre-clinical atherosclerosis intima-media thickness as well as coronary calcium scoring are most frequently used. However, beyond these two there are other parameters derived by ultrasound and multi-detector computed tomography as well as magnetic resonance imaging and nuclear/molecular imaging which are discussed in the chapter. Functional tests include flow-med
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Cleverley, Joanne. The imaging of fungal disease. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0041.

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The imaging of fungal infection is diverse and often non-specific with multiple abnormalities commonly identified, frequently with more than one organ involved. By correlating the clinical information, which should include patient immune status, pre-existing chronic disease, and potential exposure to endemic fungi, and using this information with an awareness of the radiographic findings of fungal infection, a potential diagnosis can be ascertained. In this chapter, the imaging of fungal infection is discussed, concentrating on the various imaging modalities available, their role, and the majo
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Loving, Vilert A. Pre-Operative Localization. Edited by Christoph I. Lee, Constance D. Lehman, and Lawrence W. Bassett. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190270261.003.0059.

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Non-palpable, surgical breast lesions require image guidance to direct the site of excision. With the widespread adoption of screening mammography and increased identification of non-palpable breast cancers, image guidance is critical to support the surgeon in successful breast-conserving surgery. Pre-operative localization procedures are typically performed under mammography guidance or ultrasound guidance, and less commonly under magnetic resonance imaging (MRI) guidance. This chapter, appearing in the section on interventions and surgical changes, reviews protocols and pitfalls, pre-/peri-/
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Splinter, Robert, and Kayvan Najarian. Biomedical Signal and Image Processing. Taylor & Francis Group, 2016.

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Splinter, Robert, and Kayvan Najarian. Biomedical Signal and Image Processing. Taylor & Francis Group, 2016.

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Kayvan, Najarian, and Splinter Robert, eds. Biomedical signal and image processing. Boca Raton, FL: CRC/Taylor & Francis, 2005.

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Splinter, Robert, and Kayvan Najarian. Biomedical Signal and Image Processing. Taylor & Francis Group, 2016.

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Wang, Sigen, Otto Zhou, and Sha Chang. Carbon-nanotube field emission electron and X-ray technology for medical research and clinical applications. Edited by A. V. Narlikar and Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533060.013.19.

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This article describes carbon-nanotube based X-ray technologies for medical research and clinical applications, including an X-ray source, microfocus X-ray tube, microcomputed tomography scanner, stationary digital breast tomosynthesis, microradiotherapy system, and single-cell irradiation system. It first examines electron field emission from carbon nanotubes before discussing carbon-nanotube field emission electron and X-ray technologies in greater detail. It highlights the enormous promise of these systems in commercial and research application for the future in diagnostic medical imaging;
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McCormick, Patrick Neil. Pre-clinical evaluation of [carbon-11]-(+)-PHNO as an agonist positron emission tomography (PET) radiotracer for imaging of the high-affinity state of the dopamine D2 receptor. 2006.

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Book chapters on the topic "Pre-clinical imaging"

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Rasey, Janet S., Gary V. Martin, and Kenneth A. Krohn. "Quantifying Hypoxia with Radiolabeled Fluoromisonidazole: Pre-Clinical and Clinical Studies." In Imaging of Hypoxia, 85–117. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-017-1828-8_6.

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Hill, Melissa L., Kela Liu, James G. Mainprize, Ronald B. Levitin, Rushin Shojaii, and Martin J. Yaffe. "Pre-clinical Evaluation of Tumour Angiogenesis with Contrast-Enhanced Breast Tomosynthesis." In Breast Imaging, 1–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-31271-7_1.

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André, M. P., C. H. Barker, N. Sekhon, J. Wiskin, D. Borup, and K. Callahan. "Pre-Clinical Experience with Full-Wave Inverse-Scattering for Breast Imaging." In Acoustical Imaging, 73–80. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-8823-0_10.

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Lyons, Scott K., and Kevin M. Brindle. "Molecular Imaging of Cancer and the Implications for Pre-invasive Disease." In Pre-Invasive Disease: Pathogenesis and Clinical Management, 167–207. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6694-0_10.

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Bringout, Gael, Hanne Wojtczyk, Mandy Grüttner, Matthias Graeser, Wiebke Tenner, Julian Hägele, Florian M. Vogt, Jörg Barkhausen, and Thorsten M. Buzug. "Safety Aspects for a Pre-clinical Magnetic Particle Imaging Scanner." In Springer Proceedings in Physics, 355–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-24133-8_57.

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Nadjmi, Maschallah. "MRI of Syringomyelia: Comparison of Pre-Postoperative Results with Clinical Symptoms." In Imaging of Brain Metabolism Spine and Cord Interventional Neuroradiology Free Communications, 187–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74337-5_48.

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Lao, Yi, Sinchai Tsao, and Natasha Lepore. "Computer Aided Diagnosis in Pre-Clinical Dementia: From Single-Modal Metrics to Multi-Modal Fused Methodologies." In Big Data in Multimodal Medical Imaging, 47–70. Boca Raton : CRC Press, [2020]: Chapman and Hall/CRC, 2019. http://dx.doi.org/10.1201/b22410-3.

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Frostig, Ron D. "Intrinsic Signal Optical Imaging (ISOI): State-of-the-Art with Emphasis on Pre-clinical and Clinical Studies." In Brain Informatics and Health, 111–27. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6883-1_5.

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Gomes, C. M., M. M. Welling, I. Que, N. Henriquez, G. van der Pluijm, A. J. Abrunhosa, M. F. Botelho, P. C. W. Hogendoorn, E. K. J. Pauwels, and A. M. Cleton-Jansen. "Imaging Multidrug Resistance in Osteosarcoma: A Pre-clinical Approach Using an Orthotopic Animal Model." In IFMBE Proceedings, 784–87. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03879-2_219.

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Denisko, Danielle, Samuel Oduneye, Philippa Krahn, Sudip Ghate, Ilan Lashevsky, Graham Wright, and Mihaela Pop. "Analysis of Activation-Recovery Intervals from Intra-cardiac Electrograms in a Pre-clinical Chronic Model of Myocardial Infarction." In Functional Imaging and Modelling of the Heart, 280–88. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59448-4_27.

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Conference papers on the topic "Pre-clinical imaging"

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WIEBE, LEONARD I. "MEDICAL IMAGING APPLICATIONS IN PRE-CLINICAL AND CLINICAL MEDICINE." In Proceedings of the 3rd International Conference on Isotopes. WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812793867_0046.

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Cruje, Charmainne, Justin J. Tse, David W. Holdsworth, Elizabeth R. Gillies, and Maria Drangova. "Blood-pool contrast agent for pre-clinical computed tomography." In SPIE Medical Imaging, edited by Thomas G. Flohr, Joseph Y. Lo, and Taly Gilat Schmidt. SPIE, 2017. http://dx.doi.org/10.1117/12.2255581.

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Weis, Jared A., Thomas E. Yankeelov, Samantha A. Munoz, Rahul A. Sastry, Stephanie L. Barnes, Lori R. Arlinghaus, Xia Li, and Michael I. Miga. "A consistent pre-clinical/clinical elastography approach for assessing tumor mechanical properties in therapeutic systems." In SPIE Medical Imaging, edited by John B. Weaver and Robert C. Molthen. SPIE, 2013. http://dx.doi.org/10.1117/12.2007425.

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Cruje, Charmainne, David W. Holdsworth, Elizabeth R. Gillies, and Maria Drangova. "High-concentration gadolinium nanoparticles for pre-clinical vascular imaging." In Physics of Medical Imaging, edited by Guang-Hong Chen, Joseph Y. Lo, and Taly Gilat Schmidt. SPIE, 2018. http://dx.doi.org/10.1117/12.2293016.

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Parnham, K. B., S. Chowdhury, J. Li, D. J. Wagenaar, and B. E. Patt. "Second-Generation, Tri-Modality Pre-Clinical Imaging System." In 2006 IEEE Nuclear Science Symposium Conference Record. IEEE, 2006. http://dx.doi.org/10.1109/nssmic.2006.354244.

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Wu, Yanjun, Jeremy W. Wellen, and Susanta K. Sarkar. "Multi-modality molecular imaging: pre-clinical laboratory configuration." In Biomedical Optics 2006, edited by Fred S. Azar and Dimitris N. Metaxas. SPIE, 2006. http://dx.doi.org/10.1117/12.660244.

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Tibbelin, Sandra, Peter Nillius, Björn Cederström, and Mats Danielsson. "HyperSPECT: a new system for pre-clinical imaging in vivo." In SPIE Medical Imaging, edited by Ehsan Samei and Jiang Hsieh. SPIE, 2009. http://dx.doi.org/10.1117/12.812964.

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Vogel, P., S. Herz, M. A. Ruckert, C. Brede, A. Brandl, T. Kampf, S. Veldhoen, et al. "Traveling wave MPI goes pre-clinical application." In 2015 5th International Workshop on Magnetic Particle Imaging (IWMPI). IEEE, 2015. http://dx.doi.org/10.1109/iwmpi.2015.7106997.

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Guggenheim, James A., Hector R. A. Basevi, Iain B. Styles, Jon Frampton, and Hamid Dehghani. "Bioluminescence tomography improves quantitative accuracy for pre-clinical imaging." In European Conferences on Biomedical Optics, edited by Paola Taroni and Hamid Dehghani. SPIE, 2013. http://dx.doi.org/10.1117/12.2033317.

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Du, Louise Y., Ting-Yim Lee, and David W. Holdsworth. "Image quality assessment of a pre-clinical flat-panel volumetric micro-CT scanner." In Medical Imaging, edited by Michael J. Flynn and Jiang Hsieh. SPIE, 2006. http://dx.doi.org/10.1117/12.650970.

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Reports on the topic "Pre-clinical imaging"

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Gilland, David R. Pre-clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices. Fort Belvoir, VA: Defense Technical Information Center, October 2009. http://dx.doi.org/10.21236/ada564056.

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Gilland, David R. Pre-clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices. Fort Belvoir, VA: Defense Technical Information Center, October 2010. http://dx.doi.org/10.21236/ada585696.

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Gilland, David R. Pre-Clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices. Fort Belvoir, VA: Defense Technical Information Center, June 2006. http://dx.doi.org/10.21236/ada585792.

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Gilland, David R. Pre-Clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices. Fort Belvoir, VA: Defense Technical Information Center, November 2007. http://dx.doi.org/10.21236/ada585791.

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