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Journal articles on the topic 'Pre-ganglionic injury'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

O'Shea, K., J. H. Feinberg, and S. W. Wolfe. "Imaging and electrodiagnostic work-up of acute adult brachial plexus injuries." Journal of Hand Surgery (European Volume) 36, no. 9 (2011): 747–59. http://dx.doi.org/10.1177/1753193411422313.

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Imaging and electrodiagnostic studies form an essential part of the evaluation of the patient with traumatic brachial plexopathy, enabling clarification of surgical options, prognostication of outcome and formulation of postoperative management. The primary objective of imaging is to identify pre-ganglionic injury indicative of nerve root avulsion. The presence of one or more nerve root avulsion injuries is a critical factor in surgical decision-making and the prognosis of surgical reconstruction. CT myelography is the current imaging modality of choice for this purpose. Initial electrodiagnos

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2

Ochiai, Hidenobu, Tomoaki Ikeda, Kenichi Mishima, et al. "Development of a novel experimental rat model for neonatal pre-ganglionic upper brachial plexus injury." Journal of Neuroscience Methods 119, no. 1 (2002): 51–57. http://dx.doi.org/10.1016/s0165-0270(02)00167-x.

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3

ROSSON, J. W. "Disability following Closed Traction Lesions of the Brachial Plexus Sustained in Motor Cycle Accidents." Journal of Hand Surgery 12, no. 3 (1987): 353–55. http://dx.doi.org/10.1016/0266-7681_87_90187-2.

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102 patients with closed traction lesion of the brachial plexus resulting from motor cycle accidents have been studied. The majority were young men, with the dominant arm involved in 64%. 74% of the patients underwent early operative exploration and 54% of these were amenable to at least partial repair. 65% of the patients had sustained irreparable pre-ganglionic injury to at least three roots of the plexus. 74% of the patients had sustained additional injuries in the accident. Subsequent reconstructive procedures were performed in 26% of patients. 60% of the patients regained employment, but

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MCCAUL, J., H. SHARMA, and T. E. HEMS. "Extrapleural Apical Fluid Collection: An Important Sign on Plain X-ray Suggesting a Pre-ganglionic Brachial Plexus Injury." Journal of Hand Surgery (European Volume) 33, no. 4 (2008): 501–6. http://dx.doi.org/10.1177/1753193408090100.

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Forty of 136 consecutive patients referred for management of brachial plexus injuries had closed supraclavicular injuries. The results of the initial chest X-rays were available for 29 patients. Nine had avulsion of the C8 and T1 nerve roots from the spinal cord. Eight cases had MR confirmation of lower root avulsion, six of these cases were confirmed surgically and none had any long-term clinical recovery. Twenty had partial brachial plexus injuries without avulsion of these roots. Seven of nine patients with avulsion of C8 and T1 had an extrapleural apical fluid collection. One of these had

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Al-Hourani, Khalid, David Gamble, Paul Armstrong, Greg O’Neill, and James Kirkpatrick. "The Predictive Value of Ultrasound Scanning in Certain Hand and Wrist Conditions." Journal of Hand Surgery (Asian-Pacific Volume) 23, no. 01 (2018): 76–81. http://dx.doi.org/10.1142/s2424835518500108.

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Background: Fast and accurate diagnosis of conditions of the hand and wrist is essential in guiding management. We aimed to analyse the predictive value of ultrasound in identifying different pathologies in the hand and wrist by correlating pre-operative ultrasound findings with per-operative surgical findings. Methods: We retrospectively reviewed the case notes of all patients under the care of the senior author on whom a hand/wrist ultrasound had been performed between January 2007–May 2013. Of these only patients who proceeded to surgery were included as this was the correlating endpoint. P

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VERONESI, BRUNO AZEVEDO, MARCELO BORDALO RODRIGUES, MARINA TOMMASINI CARRARA DE SAMBUY, RODRIGO SOUSA MACEDO, ÁLVARO BAIK CHO, and MARCELO ROSA DE REZENDE. "USE OF MAGNETIC RESONANCE IMAGING TO DIAGNOSE BRACHIAL PLEXUS INJURIES." Acta Ortopédica Brasileira 26, no. 2 (2018): 131–34. http://dx.doi.org/10.1590/1413-785220182602187223.

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ABSTRACT Objective: To compare magnetic resonance imaging and intraoperative findings in patients diagnosed with traumatic injury to the brachial plexus. Methods: Patients with a diagnosis of traumatic injury to the brachial plexus admitted to the hand and microsurgery outpatient consult of the Hospital das Clínicas at the University of São Paulo were selected during December 2016. A total of three adult patients with up to six months of injury who underwent surgical treatment were included in the study. A diffusion-weighted sequence magnetic resonance protocol and fluid-sensitive volumetric r

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Ramachandran, Anupama, Manisha Jana, Atin Kumar, et al. "Evaluation of Infantile Brachial Plexopathy Using 3T MRI and High-Resolution Ultrasound: Experience From a Tertiary Care Centre." Neurology India 72, no. 2 (2024): 326–33. http://dx.doi.org/10.4103/ni.ni_818_21.

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Background: Currently, clinical assessment is the main tool for the evaluation of brachial plexus injury, complemented by electrophysiologic studies (EPS), and imaging studies whenever available. Imaging plays an important role as it enables the differentiation of pre-ganglionic and postganglionic injuries, and adds objectivity to presurgical evaluation. Objectives: The primary objective was to evaluate the utility of magnetic resonance imaging (MRI) and high-resolution ultrasonography (USG) in the localization and characterization of brachial plexus injury in infants. Materials and Methods: I

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8

Caporrino, F. A., L. Moreira, V. Y. Moraes, J. C. Belloti, J. B. Gomes dos Santos, and F. Faloppa. "BRACHIAL PLEXUS INJURIES: DIAGNOSIS PERFORMANCE AND RELIABILITY OF EVERYDAY TOOLS." Hand Surgery 19, no. 01 (2014): 7–11. http://dx.doi.org/10.1142/s0218810414500026.

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Purpose: Determining the patterns of brachial plexus injuries is challenging. Diagnostic methods have been used to facilitate diagnosis, but there is no consensus regarding which tool best complements physical examination (PE). Magnetic resonance imaging (MRI) and nerve conduction studies (NCSs) are instruments with widespread use and feasibility for everyday assessment. In this study, we evaluated the diagnostic performance of these diagnostic instruments and PE. We also assessed the agreement in the PE and diagnostic instrument findings of two experienced and certified hand surgeons. Methods

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9

Rukmana Tri Pratistha, Indra, Nyoman Gede Bimantara, I. Gede Mahardika Putra, Made Bramantya Karna, Anak Agung Gde Yuda Asmara, and Putu Feryawan Meregawa. "Nerves Transfer Procedure in Patients with Left Upper Extremities Weakness Following Gunshot Wounds: A Case Report." Open Access Macedonian Journal of Medical Sciences 9, no. C (2021): 140–45. http://dx.doi.org/10.3889/oamjms.2021.6393.

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BACKGROUND: Gunshot wounds (GSWs) to the extremities can result in damage to the neurovascular structure which results in high morbidity and loss of function. According to the Centers for Disease Control report, the incidence of non-fatal GSWs has increased in the past decade. Trauma to the brachial plexus is a type of peripheral nerve trauma that is most difficult to treat due to its complex surgical procedures. Early exploration and reconstruction of peripheral nerve trauma are still being debated to this day. However, most recommend surgical exploration when the suspicion of neurovascular t

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10

Vihar, Kovachev. "Single Nerve Transfer in Case of Partial Pre-Ganglionic Injury C5 and Avulsion Injury C6." Clinical Case Reports Journal 4, no. 4 (2023). https://doi.org/10.5281/zenodo.14884526.

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Introduction: Loss of active abduction and external rotation of the shoulder, as well as flexion of the elbow, at high lesions C5 C6 present challenges in orthopedic surgery. Aim: The study aimed to estimate the possibility of recovery of the shoulder girdle and elbow function through a single intrapleural nerve transfer in stated lesions. Materials and methods: We present a case of a patient with a partial high lesion of C5 and avulsion C6, who was treated through single nerve transfer from the radial nerve and median nerve to the musculocutaneous and axillary nerve. Results: A

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11

Wu, Kitty Y., Derek B. Asserson, Michelle F. Loosbrock, Allen T. Bishop, Robert J. Spinner, and Alexander Y. Shin. "Clinical Predictors of C5 Spinal Nerve Viability in Pan-Brachial Plexus Injuries." Plastic & Reconstructive Surgery, July 4, 2023. http://dx.doi.org/10.1097/prs.0000000000010906.

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Backgrounds: In pan-brachial plexus injury patients, distinguishing between pre-ganglionic and post-ganglionic injuries is crucial to reconstructive planning. This study aimed to identify pre-operative factors that would accurately predict a reconstructible C5 spinal nerve. Methods: Pan-brachial plexus injury patients from a single institution between 2001 and 2018 were reviewed. Patient demographics, clinical examination, diagnostic imaging, and electrodiagnostic results were recorded. C5 viability was determined based on supraclavicular exploration and intraoperative electrophysiologic testi

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12

Jr, Kingma JG, Simard D, and Rouleau JR. "Left Ventricular Function after Acute Ischemia-Reperfusion Injury in Cardiac Decentralized Dogs Subject to Ischemic Conditioning." CARDIOLOGY & CARDIOVASCULAR RESEARCH 1, no. 1 (2023). http://dx.doi.org/10.52106/2996-3885.1001.

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Objective: Ischemic conditioning (IC) mediated protection against ischemic injury continues independent of extrinsic cardiac nerve status; however, controversy persists regarding its ability to limit ischemia-mediated LV contractile dysfunction. Here, we investigate the acute cardiac consequences of loss of sympathetic and parasympathetic inputs to the local cardiac neuronal hierarchy on post-ischemic LV function. Additionally, we examined whether IC could affect potential recovery of LV function. Methods: Anesthetized, open-chest dogs were randomly distributed to surgical nerve ablation or ga

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13

Patel, Neehar R., Anupam B. Takwale, K. A. Mansukhani, Sunila Jaggi, and Mukund R. Thatte. "Correlation of Magnetic Resonance Imaging (Neurography) and Electrodiagnostic Study Findings with Intraoperative Findings in Post Traumatic Brachial Plexus Palsy." Indian Journal of Plastic Surgery, December 22, 2022. http://dx.doi.org/10.1055/s-0042-1760253.

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Abstract Background The majority of brachial plexus injuries (BPIs) are caused by trauma; most commonly due to two-wheeler road accidents. It is important to determine whether the lesion in question is pre-ganglionic or post-ganglionic for purposes of surgical planning and prognosis. Diagnostic testing helps the surgeon to not only decide whether surgical intervention is required, but also in planning the procedure, thereby maximizing the patient's chances of early return to function. The aim of the study was to determine the diagnostic efficacy of electrodiagnostic studies (Edx) and magnetic

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14

Lujan, Heidi L., Rebecca A. Mulder, and Stephen E. DiCarlo. "Chronic, complete cervical_6‐7 cord injury: distinct autonomic, cardiac and vascular deficits." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.1077.6.

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Spinal cord injury (SCI) resulting in tetraplegia is a devastating, life‐changing injury causing paralysis and sensory impairment as well as autonomic dysfunction that triggers compromised cardiovascular, bowel, bladder and sexual activity. Life becomes a battle for independence as even routine bodily functions and the smallest activity of daily living become a major challenge. The human physiology, mind and spirit are wonderfully adaptable as individuals with tetraplegia find ways to adjust. However, addressing autonomic losses and cardiovascular consequences would greatly improve the quality

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15

Lima, B. H. M., L. P. Cartarozzi, S. Kyrylenko, R. S. Ferreira, B. Barraviera, and Alexandre L. R. Oliveira. "Embryonic stem cells overexpressing high molecular weight FGF2 isoform enhance recovery of pre-ganglionic spinal root lesion in combination with fibrin biopolymer mediated root repair." Stem Cell Research & Therapy 15, no. 1 (2024). http://dx.doi.org/10.1186/s13287-024-03676-6.

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Abstract Background Spinal ventral root avulsion results in massive motoneuron degeneration with poor prognosis and high costs. In this study, we compared different isoforms of basic fibroblast growth factor 2 (FGF2), overexpressed in stably transfected Human embryonic stem cells (hESCs), following motor root avulsion and repair with a heterologous fibrin biopolymer (HFB). Methods In the present work, hESCs bioengineered to overexpress 18, 23, and 31 kD isoforms of FGF2, were used in combination with reimplantation of the avulsed roots using HFB. Statistical analysis was conducted using GraphP

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16

Sachdeva, Rahul, Rayshad Gopaul, Mengyao Jia, Aaron Monga, Matt Ramer, and Andrei V. Krassioukov. "A Triple Combination Approach Involving Nerve Transplantation, Glial Scar Digestion and Passive Exercise Promotes Cardiovascular Recovery after Spinal Cord Injury." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.1077.7.

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IntroductionCardiovascular (CV) dysfunction is the leading cause of morbidity and mortality after spinal cord injury (SCI). SCI causes CV dysfunction primarily by (a) the direct loss of critical medullary control of sympathetic pre‐ganglionic neurons and, (b) the aberrant sprouting of nociceptive afferent fibers within the spinal cord. To promote significant CV recovery after SCI, we developed a triple combination approach to simultaneously promote axonal regeneration to regain the supraspinal vasomotor control as well as to reduce aberrant sprouting of nociceptive afferent fibers in an experi

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