Relevant bibliographies by topics / Prediabetic State/metabolism

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters

Academic literature on the topic 'Prediabetic State/metabolism'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Prediabetic State/metabolism"

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Akinnuga, Akinjide Moses, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, and Andile Khathi. "Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model." Canadian Journal of Gastroenterology and Hepatology 2020 (February 20, 2020): 1–9. http://dx.doi.org/10.1155/2020/2475301.

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Background. Prediabetes is an intermediary hyperglycaemic state that precedes type 2 diabetes mellitus (T2DM) in which abnormal metabolism of glucose and lipids occurs in organs such as the liver. Evidence has shown that, about 70% of T2DM patients develop hepatic dysfunction which is found to begin during the prediabetic stage. Bredemolic acid, a pentacyclic triterpene, has been found to improve insulin sensitivity in diet-induced prediabetic rats. The effects of this compound on liver function, however, are unknown. This study was therefore designed to investigate the effects of BA on liver
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de Souza, Milena Cremer, Maria Luisa Gonçalves Agneis, Karoliny Alves das Neves, et al. "Melatonin Improves Lipid Homeostasis, Mitochondrial Biogenesis, and Antioxidant Defenses in the Liver of Prediabetic Rats." International Journal of Molecular Sciences 26, no. 10 (2025): 4652. https://doi.org/10.3390/ijms26104652.

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Type 2 diabetes mellitus represents a major global health burden and is often preceded by a prediabetic state characterized by insulin resistance and metabolic dysfunction. Mitochondrial alterations, oxidative stress, and disturbances in lipid metabolism are central to the prediabetes pathophysiology. Melatonin, a pleiotropic indolamine, is known to regulate metabolic and mitochondrial processes; however, its therapeutic potential in prediabetes remains poorly understood. This study investigated the effects of melatonin on energy metabolism, oxidative stress, and mitochondrial function in a ra
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de Wit-Verheggen, Vera H. W., and Tineke van de Weijer. "Changes in Cardiac Metabolism in Prediabetes." Biomolecules 11, no. 11 (2021): 1680. http://dx.doi.org/10.3390/biom11111680.

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In type 2 diabetes mellitus (T2DM), there is an increased prevalence of cardiovascular disease (CVD), even when corrected for atherosclerosis and other CVD risk factors. Diastolic dysfunction is one of the early changes in cardiac function that precedes the onset of cardiac failure, and it occurs already in the prediabetic state. It is clear that these changes are closely linked to alterations in cardiac metabolism; however, the exact etiology is unknown. In this narrative review, we provide an overview of the early cardiac changes in fatty acid and glucose metabolism in prediabetes and its co
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Shestakova, Ekaterina A., Elena Y. Lunina, Gagik R. Galstyan, Marina V. Shestakova, and Ivan I. Dedov. "Type 2 diabetes and prediabetes prevalence in patients with different risk factor combinations in the NATION study." Diabetes mellitus 23, no. 1 (2020): 4–11. http://dx.doi.org/10.14341/dm12286.

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BACKGROUND: Type 2 diabetes (T2D) is multifactorial disease. NATION epidemiological study may provide the information about the prevalence of T2D and prediabetic state in patients with different risk factor combinations in Russian population.
 AIMS: To evaluate the prevalence of T2D and prediabetic state in NATION cohort depending on the amount of diabetes risk factors.
 MATERIALS AND METHODS: NATION is an epidemiological, cross-sectional study, designed to assess the prevalence of T2D in Russian adult population, where HbA1c was used to establish T2D (HbAc6,5%) and prediabetes (5,7%
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Baranowska-Jurkun, Angelika, Wojciech Matuszewski, and Elżbieta Bandurska-Stankiewicz. "Chronic Microvascular Complications in Prediabetic States—An Overview." Journal of Clinical Medicine 9, no. 10 (2020): 3289. http://dx.doi.org/10.3390/jcm9103289.

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A prediabetic state is a major risk factor for the development of diabetes, and, because of an identical pathophysiological background of both conditions, their prevalence increases parallelly and equally fast. Long-term hyperglycemia is the main cause inducing chronic complications of diabetes, yet the range of glucose levels at which they start has not been yet unequivocally determined. The current data show that chronic microvascular complications of diabetes can be observed in patients with abnormal glucose metabolism in whom glycaemia is higher than optimal but below diagnostic criteria f
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Abdollahi, Milad, Sayyed Mohammad Marandi, Kamran Ghaedi, et al. "Insulin-Related Liver Pathways and the Therapeutic Effects of Aerobic Training, Green Coffee, and Chlorogenic Acid Supplementation in Prediabetic Mice." Oxidative Medicine and Cellular Longevity 2022 (February 24, 2022): 1–14. http://dx.doi.org/10.1155/2022/5318245.

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Background. The liver controls blood glucose levels via regulation of anabolic (glycogen synthesis and gluconeogenesis) and catabolic (glycolysis and glycogenolysis) processes through activation of the PI3K-AKT signalling pathway. The aim of this study was to assess the effect of aerobic training, green coffee, and chlorogenic acid supplementation on glucose metabolism-regulating pathways in prediabetic mice. Methods. C57BL/6 mice were exposed to a high-fat diet and physical activity limitation to induce a state of prediabetes. After 12 weeks, mice were fed a high-fat diet compared to the cont
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Papaetis, Georgios S. "Liraglutide Therapy in a Prediabetic State: Rethinking the Evidence." Current Diabetes Reviews 16, no. 7 (2020): 699–715. http://dx.doi.org/10.2174/1573399816666191230113446.

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Background: Prediabetes is defined as a state of glucose metabolism between normal glucose tolerance and type 2 diabetes. Continuous β-cell failure and death are the reasons for the evolution from normal glucose tolerance to prediabetes and finally type 2 diabetes. Introduction: The necessity of new therapeutic approaches in order to prevent or delay the development of type 2 diabetes is obligatory. Liraglutide, a long-acting GLP-1 receptor agonist, has 97% homology for native GLP-1. Identification of the trophic and antiapoptotic properties of liraglutide in preclinical studies, together with
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Paprott, Rebecca, Christa Scheidt-Nave, and Christin Heidemann. "Determinants of Change in Glycemic Status in Individuals with Prediabetes: Results from a Nationwide Cohort Study in Germany." Journal of Diabetes Research 2018 (October 14, 2018): 1–12. http://dx.doi.org/10.1155/2018/5703652.

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Previous studies investigating determinants of changes in glycemic status among individuals with prediabetes mainly focused on glucose-defined prediabetes. In this study, we examined determinants of a regression to normoglycemia or a progression to diabetes among individuals with HbA1c-defined prediabetes. The study included 817 participants (18–79 years) with prediabetes (HbA1c 5.7–6.4% (39–47 mmol/mol)) at baseline. Glycemic status at follow-up was categorized as diagnosed diabetes (self-reported physician diagnosis or antidiabetic medication), undiagnosed diabetes (HbA1c ≥ 6.5% (≥48 mmol/mo
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Knezek, Savanah, Marielle Engelen, Gabriella Ten Have, John Thaden, and Nicolaas Deutz. "Prediabetes Is Associated with Specific Changes in Valine Metabolism." Current Developments in Nutrition 6, Supplement_1 (2022): 34. http://dx.doi.org/10.1093/cdn/nzac047.034.

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Abstract Objectives Recent studies have suggested that a high plasma concentration of the branched-chain amino acids (BCAAs) can serve as a biomarker for type-2-diabetes (T2D). Whether this is also the case for prediabetes remains unclear. Our goal is to examine whether specific disturbances exist in the kinetics of the BCAAs leucine, isoleucine and valine in middle aged/older adults with prediabetes. Methods We measured BCAA kinetics in 70 prediabetic subjects (fasting glucose: 5.7-6.5 mM), 47 diabetic subjects (fasting glucose: ≥6.5 mM, or are taking medication to control blood glucose) and
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Dreval', Alexander Vasil'evich, Irina Vladimirovna Trigolosova, and Inna Vladimirovna Misnikova. "Leptin secretion and severity of glycemic disorders in women with body weight excess." Diabetes mellitus 16, no. 2 (2013): 67–72. http://dx.doi.org/10.14341/2072-0351-3758.

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Aim. To characterize leptin secretion in fasting state and upon intravenous glucose administration in patients with type 2 diabetes mel- litus (T2DM), prediabetes and obesity. Materials and methods. 59 female patients took part in this study: 12 had no signs of glycemic disorder, 18 were diagnosed with prediabetes and 30 ? with newly diagnosed T2DM. Median age was 54 [48.6?60] years, median BMI ? 33.2 [29.0?37.2] kg/m2. All participants were tested for fasting leptin, fasting insulin and blood glucose levels. Prediabetic and diabetic subjects also received a bolus intravenous injection of 40%
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Dissertations / Theses on the topic "Prediabetic State/metabolism"

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Patarrão, Rita Susana Franco das Neves. "Fast-to-fed shift in glucose homeostasis: clues to an earlier detection of human prediabetic states." Doctoral thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2010. http://hdl.handle.net/10362/4802.

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FCM: UC Bioquímica I - PhD Thesis<br>A acção da insulina está associada à libertação da substância hepática sensibilizadora da insulina (HISS), que aumenta o aporte de glucose periférico. No estado pós-prandial, a libertação da HISS é máxima, diminuindo com o período de jejum. O controlo prandial da acção da HISS é mediado pelo sistema parassimpático hepático/óxido nítrico (NO) e pelo glutationo (GSH) hepático. Os actuais métodos utilizados para avaliar a sensibilidade à insulina são realizados no estado de jejum. A presente dissertação destaca a hipótese de que o mecanismo dependente da H
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Books on the topic "Prediabetic State/metabolism"

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International Symposium on Early Diabetes (5th 1988 Puerto Iguazú, Argentina). Prediabetes. Plenum Press, 1988.

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Zvi, Laron, and Karp Moshe, eds. Prediabetes, are we ready to intervene?: 8th International Beilinson Symposium on Prediabetes, Herzliya, October 20-25, 1991. Karger, 1993.

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Codario, Ronald A. Type 2 diabetes, pre-diabetes, and the metabolic syndrome: The primary care guide to diagnosis and management. Humana Press, 2005.

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Camerini-Davalos, Rafael A., and Harold S. Cole. Prediabetes. Springer, 2012.

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Camerini-Davalos, Rafael A., and Harold S. Cole. Prediabetes. Springer London, Limited, 2013.

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Laron, Zvi, and M. Karp. Prediabetes, Are We Ready to Intervene?: 8th International Beilinson Symposium on Prediabetes, Herzliya, October 20-25, 1991 (Pediatric and Adolescent Endocrinology). S. Karger Publishers (USA), 1993.

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Codario, Ronald A. Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome. Humana Press, 2010.

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Codario, Ronald A. Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome. Humana Press, 2005.

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Codario, Ronald A. Type 2 Diabetes, Pre-Diabetes, and the Metabolic Syndrome (Current Clinical Practice). Humana Press, 2005.

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Book chapters on the topic "Prediabetic State/metabolism"

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Hezekiel Mphasha, Mabitsela. "Bridging the Gap: Exploring How Fruit and Vegetable Consumption Shapes Gut Microbiota in Prediabetes." In Metabolic Syndrome - Lifestyle and Biological Risk Factors [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.114237.

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Prevalence of prediabetes is increasing globally and a public health concern because it is transitional stage between normoglycemia and diabetes. Therefore, effective interventions are essential to curb its progression. Consumption of fruits and vegetables is vital for overall health and associated with improved insulin sensitivity, reduced oxidative stress, and regulation of inflammatory pathways. Notably, the interplay between dietary choices and gut microbiota composition has emerged as a novel aspect of metabolic health. Antioxidants present in fruits and vegetables contribute to gut barri
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Adegoke Azeez, Taoreed. "Present State and Perspectives of Type 2 Diabetes Management." In Type 2 Diabetes in 2024 - From Early Suspicion to Effective Management. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1002447.

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Diabetes mellitus is a common metabolic disorder characterised by chronic hyperglycaemia that results from a defect in insulin secretion, action, or both. There are different types of diabetes mellitus, but type 2 diabetes mellitus is the most common type globally. Type 2 diabetes mellitus results from a complex interaction between predisposing genes and unhealthy lifestyle choices. The risk factors for type 2 diabetes include obesity, prediabetes, sedentary lifestyle, unhealthy diets, and hypertension. Poorly controlled diabetes causes microvascular and macrovascular complications. The goals
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Journal articles
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