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Journal articles on the topic 'Predictor of Malaria'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Sineke, Mohammad F. D., Suryadi N. N. Tatura, and Novie H. Rampengan. "Faktor-faktor Prediktor Luaran Malaria Berat pada Anak." Medical Scope Journal 5, no. 2 (2023): 188–97. http://dx.doi.org/10.35790/msj.v5i2.45486.

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Abstract: Symptoms and severity of malaria infection differ between adults and children. Severe malaria is more common in children than in adults. Severe malaria cases in children can give clinical manifestations that are more fatal, severe and even death. This study aimed to determine the predictor factors of severe malaria outcomes in children. This was a literature review study using Google Scholar database. The results obtained 11 articles that met the inclusion and exclusion criteria. It was found that the clinical form and/or complications of severe malaria, co-infection and severe acute

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Omale, Ugwu I., Benedict N. Azuogu, Adaoha P. Agu, and Edmund N. Ossai. "Use of malaria rapid diagnostic test and anti-malarial drug prescription practices among primary healthcare workers in Ebonyi state, Nigeria: An analytical cross-sectional study." PLOS ONE 19, no. 6 (2024): e0304600. http://dx.doi.org/10.1371/journal.pone.0304600.

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Background The recommendation of universal diagnostic testing before malaria treatment aimed to address the problem of over-treatment with artemisinin-based combination therapy and the heightened risk of selection pressure and drug resistance and the use of malaria rapid diagnostic test (MRDT) was a key strategy, particularly among primary healthcare (PHC) workers whose access to and use of other forms of diagnostic testing were virtually absent. However, the use of MRDT can only remedy over-treatment when health workers respond appropriately to negative MRDT results by not prescribing anti-ma

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Vemula, Sachin, Vidyalakshmi Katara, Unnikrishnan Bhaskaran, Sushma Adappa, and Mahabala Chakrapani. "Pretreatment elevated erythrocyte sedimentation rate and C-reactive protein as a predictor of malarial complications." Journal of Infection in Developing Countries 10, no. 12 (2016): 1332–37. http://dx.doi.org/10.3855/jidc.8053.

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Introduction: Complications of malaria can develop suddenly and unexpectedly. Although various parameters have been associated with severity of malaria, they have not been studied as predictors of these events. Many of the malarial complications are inflammatory in nature, and C-reactive protein (CRP) and elevated erythrocyte sedimentation rate (ESR) could be early markers of these complications and might precede and predict the development of complications. Methodology: A total of 122 inpatients with uncomplicated newly diagnosed malaria were studied. CRP, ESR, hemoglobin, and platelets were

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Akshay, Louis Dias, and D. Sumanth. "Usefulness of Various Peripheral Blood Leukocyte Count ratios in Malaria Evaluation." International Journal of Health Sciences and Pharmacy (IJHSP) 1, no. 2 (2017): 52–60. https://doi.org/10.5281/zenodo.1043523.

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Malaria is a major public health problem in India. Changes in blood cell counts are a well-known feature of malaria. Hence an attempt has been made to assess the role of leucocyte ratios in malaria as predictors of malaria infection and its clinical severity. <strong>Methods:</strong> A retrospective observational cohort study was carried out in a tertiary care teaching hospital over a period of 2 months. A total of 171 samples and 48 controls were included in the study. All the absolute and differential white blood cell counts were done. The neutrophil-lymphocyte count ratio (NLCR), monocyte-

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Sulistyaningsih, Erma, Rosita Dewi, Sheilla Rachmania, Irawan Fajar Kusuma, and Sahrir Sillehu. "Specific Sequence Motif of Var Gene as Predictor of Malaria Outcome." Elkawnie 10, no. 1 (2024): 52. http://dx.doi.org/10.22373/ekw.v10i1.14808.

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Abstract: The Var gene family encodes for Plasmodium falciparum Erythrocyte Membrane Protein-1 (PfEMP1), a protein responsible for malaria pathogenesis. One of the variants, the var D gene, is hypothesized as a predictor of clinical malaria outcomes. The study aimed to investigate the association between the expression of the var D gene and clinical malaria outcomes. Blood spots on filter paper from uncomplicated and severe malaria patients were collected for DNA and RNA extraction. The RNA was reverse-transcribed into cDNA. DNA and cDNA were amplified by Polymerase Chain Reaction (PCR) techni

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Jagannadham, Rajendraprasad, Sridhar Reddy K., Ashalata Tammineni, B.V.S. Kartheek, and V.Lalitha. "To Study the Significance of Hematological Parameters in Differentiating Malaria and Non-Malarial Acute Febrile Illness in a Tertiary Care Hospital in Visakhapatnam." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 551–55. https://doi.org/10.5281/zenodo.11099110.

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<strong>Background:</strong> Malaria is a common infectious disease and rarely can be life threatening if not treated properly. It is one of the major health problems in most populated areas of world [1] and an important cause of acute febrile illness in India. According to WHO’s latest world Malaria report, there were an estimated 249 million malaria cases in 2022 in 85 malaria endemic countries, increasing from 224 million in 2021. <strong>Method:</strong> The study was an observational study carried out in King George Hospital (KGH) Visakhapatnam. The study population w

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Pikatan, Orlando, Ellen Ferlita Tirtana, Kezia Seraphine, and Wienta Diarsvitri. "BIOMARKERS AND PROGNOSTIC SCORING IN CEREBRAL MALARIA." MNJ (Malang Neurology Journal) 8, no. 2 (2022): 140–43. http://dx.doi.org/10.21776/ub.mnj.2022.008.02.13.

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Malaria remains a public health concern and remain the deadliest in infectious disease in the world. Cerebral malaria is a particularly severe complication of this disease and associated with high mortality. This literature review is made up from 19 literatures consisting of journals, and book. The literature review used data base www.pubmed.com, and www.scholar.google.com using “cerebral malaria and biomarker, predictor of cerebral malaria and treatment of severe malaria”. The languages for this journal are English and Indonesian. From the collection of literatures in this literature review,

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Darnius, Open, and Dessy Siahaan. "Modelling of risk factors that influence malaria infection using Binary Logistic Regression." Journal of Physics: Conference Series 2421, no. 1 (2023): 012001. http://dx.doi.org/10.1088/1742-6596/2421/1/012001.

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Abstract Malaria is a parasitic disease that is currently endemic in many countries, including in Indonesia. Batubara District in North Sumatera is one of the malaria-endemic areas. This study was conducted to make a mathematical model based on risk factors that influence malaria infection. The data used is secondary data from other researchers. The method used to model risk factors that influence malaria infection is the binary logistic regression with a categorical response variable, namely diagnosis by microscopic examination. There are 10 variable predictors; mosquito nets (X 1), quality u

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Sumbele, Irene Ule Ngole, Sharon Odmia Sama, Helen Kuokuo Kimbi, and Germain Sotoing Taiwe. "Malaria, Moderate to Severe Anaemia, and Malarial Anaemia in Children at Presentation to Hospital in the Mount Cameroon Area: A Cross-Sectional Study." Anemia 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/5725634.

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Background. Malaria remains a major killer of children in Sub-Saharan Africa, while anaemia is a public health problem with significant morbidity and mortality. Examining the factors associated with moderate to severe anaemia (MdSA) and malarial anaemia as well as the haematological characteristics is essential.Methodology. Children (1–14 years) at presentation at the Regional Hospital Annex-Buea were examined clinically and blood samples were collected for malaria parasite detection and full blood count evaluation.Results.Plasmodium falciparum, anaemia, and malarial anaemia occurred in 33.8%,

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Shetty, Archana, Teerthanath Srinivas, and Hariprasad Srinivas. "Platelet count and Superoxide Dismutase as a marker for severity of Plasmodium infection." International Journal of Research in Medical Sciences 5, no. 11 (2017): 4864. http://dx.doi.org/10.18203/2320-6012.ijrms20174934.

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Background: Malaria continues to be an important public health problem in developing and underdeveloped countries with high morbidity and mortality. It continues to be one of the major public health problems in India. Plasmodium vivax is the major parasite type causing malaria and Plasmodium falciparum is the major cause of serious and complicated disease. Haematological abnormality which is most commonly seen in malaria is thrombocytopenia followed by anaemia. Identification of predictors of disease severity is critical to improve patient care. This study was undertaken to evaluate the severi

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Sahu, Upasana, Biranchi N. Mohapatra, Shantanu K. Kar, and Manoranjan Ranjit. "Promoter Polymorphisms in the ATP Binding Cassette Transporter Gene Influence Production of Cell-Derived Microparticles and Are Highly Associated with Susceptibility to Severe Malaria in Humans." Infection and Immunity 81, no. 4 (2013): 1287–94. http://dx.doi.org/10.1128/iai.01175-12.

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ABSTRACTMicroparticle (MP) efflux is known to be mediated by the ABCA1 protein, and the plasma level of these cell-derived MPs is elevated considerably during human malarial infection. Therefore, two polymorphisms at positions −477 and −320 in the promoter of the ABCA1 gene were genotyped and tested for association with the plasma MP level in four groups of malaria patients segregated according to the clinical severity, i.e., cerebral malaria (CM), multiorgan dysfunction (MOD), noncerebral severe malaria, and uncomplicated malaria (UM). The TruCount tube-based flow cytometric method was used f

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Njim, Tsi, and Bayee Swiri Tanyitiku. "Prognostic models for the clinical management of malaria and its complications: a systematic review." BMJ Open 9, no. 11 (2019): e030793. http://dx.doi.org/10.1136/bmjopen-2019-030793.

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ObjectiveMalaria infection could result in severe disease with high mortality. Prognostic models and scores predicting severity of infection, complications and mortality could help clinicians prioritise patients. We conducted a systematic review to assess the various models that have been produced to predict disease severity and mortality in patients infected with malaria.DesignA systematic review.Data sourcesMedline, Global health and CINAHL were searched up to 4 September 2019.Eligibility criteria for selecting studiesPublished articles on models which used at least two points (or variables)

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Hassan, A. N., M. A. Kenawy, H. Kamal, A. A. Abdel Sattar, and M. M. Sowilem. "GIS-based prediction of malaria risk in Egypt." Eastern Mediterranean Health Journal 9, no. 4 (2003): 548–58. http://dx.doi.org/10.26719/2003.9.4.548.

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Environmental variables in a malaria geographic information system [GIS] database were analysed to discriminate between governorates at high and low risk of malaria. Only Fayoum governorate was categorized as a high risk area for malaria during the last 2 decades. Discriminant models correctly classified 96.3% of the risk categories and indicated that the most important predictor of risk is hydrogeology. Further GIS spatial analysis indicated that the high malaria risk in Fayoum is associated with a unique environmental envelope of biotic [presence of both efficient malaria vectors] and abioti

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Barney, Rebecca, Miguel Velasco, Caitlin A. Cooper, et al. "Diagnostic Characteristics of Lactate Dehydrogenase on a Multiplex Assay for Malaria Detection Including the Zoonotic Parasite Plasmodium knowlesi." American Journal of Tropical Medicine and Hygiene 106, no. 1 (2022): 275–82. http://dx.doi.org/10.4269/ajtmh.21-0532.

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ABSTRACT. Plasmodium lactate dehydrogenase (pLDH) is a common target in malaria rapid diagnostic tests (RDTs). These commercial antibody capture assays target either Plasmodium falciparum–specific pLDH (PfLDH), P. vivax–specific pLDH (PvLDH), or a conserved epitope in all human malaria pLDH (PanLDH). However, there are no assays specifically targeting P. ovale, P. malariae or zoonotic parasites such as P. knowlesi and P. cynomolgi. A malaria multiplex array, carrying the specific antibody spots for PfLDH, PvLDH, and PanLDH has been previously developed. This study aimed to assess potential cro

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Alhassan, Abdul Rauf. "Pregnant Women and Malaria Preventive Measures: A Case of Tamale Teaching Hospital, Ghana." Journal of Tropical Medicine 2021 (December 7, 2021): 1–9. http://dx.doi.org/10.1155/2021/6150172.

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Background. In Saharan Africa, an estimated 25 million pregnancies are all at risk of malaria every year, with substantial morbidity and death effects for both the mother and the fetus. Aim. To investigate the use of malaria preventive measures among pregnant women patronizing antenatal services of Tamale Teaching Hospital. Methodology. This study was conducted using a descriptive cross-sectional survey of 250 participants. Data analysis was done with SPSS version 20. Graphs and tables were used to present the study data. Bivariate analysis was done using Chi-square use to determine the relati

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Han, Cong, Yahui Lin, Guangliang Shan, et al. "Plasma Concentration of Malaria Parasite-Derived Macrophage Migration Inhibitory Factor in Uncomplicated Malaria Patients Correlates with Parasitemia and Disease Severity." Clinical and Vaccine Immunology 17, no. 10 (2010): 1524–32. http://dx.doi.org/10.1128/cvi.00149-10.

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ABSTRACT Host macrophage migration inhibitory factor (MIF) has been implicated in the pathogenesis of malaria infections. Several Plasmodium parasite-derived MIFs were identified to have the potential to regulate host immune response. However, the role of Plasmodium MIFs in the immunopathogenesis of malaria infection and the relationships between these mediators and inflammatory cytokines remained unclear. In this study, we have investigated two Plasmodium MIFs in peripheral blood of uncomplicated malaria patients and analyzed their correlations with several major factors during malaria infect

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Esomonu, S. N., E. N. Ossai, and A. T. Onajole. "Knowledge of Malaria and Utilization of Insecticide-Treated Nets amongst Mothers of Under-five Children in selected Rural Communities of Nigeria’s Federal Capital Territory." Journal of Community Medicine and Primary Health Care 33, no. 1 (2021): 102–14. http://dx.doi.org/10.4314/jcmphc.v33i1.9.

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Background: Malaria is a life-threatening parasitic disease caused by the plasmodium parasite and women and under-five children are more prone to its adverse consequences. The use of insecticide-treated nets (ITNs) is recommended to reduce malaria burden in endemic communities. The study aimed to determine knowledge of malaria and utilization of insecticide-treated nets (ITNs) amongst mothers of under-five children in rural communities of Nigeria’s Federal Capital Territory, and the predictors.Methods: A community-based cross-sectional design was used. Multi-stage sampling method was used to s

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Mbah, Clarisse E., Lum A. Ambe, Adela Ngwewondo, et al. "A Comparative Study of Asymptomatic Malaria in a Forest Rural and Depleted Forest Urban Setting during a Low Malaria Transmission and COVID-19 Pandemic Period." BioMed Research International 2022 (October 15, 2022): 1–9. http://dx.doi.org/10.1155/2022/2545830.

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The global malaria morbidity and mortality witnessed an increase from 2019 to 2020 partly due to disruptions in control programs’ activities imposed by the COVID-19 pandemic. Therefore, there is still a significant burden of malaria in Cameroon which needs attention from all fronts to attain elimination goals. It is normally expected that a typical forest ecology that has undergone urbanization and subjected to high rates of ecological instabilities should also have a shift from characteristic perennial malaria transmission and a shift in the type of malaria endemicity plaguing such distorted

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Park, Sangshin, Christina E. Nixon, Olivia Miller, et al. "Impact of Malaria in Pregnancy on Risk of Malaria in Young Children: Systematic Review and Meta-Analyses." Journal of Infectious Diseases 222, no. 4 (2020): 538–50. http://dx.doi.org/10.1093/infdis/jiaa139.

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Abstract Background Our objective was to quantify the risk of acquiring malaria among progeny of women with malaria during pregnancy. Methods We searched MEDLINE, EMBASE, CINAHL, and the Cochrane Library for eligible prospective studies. The primary predictor was malaria during pregnancy defined as placental malaria, parasitemia, clinical malaria, or pregnancy-associated malaria. Primary outcomes were parasitemia or clinically defined malaria of young children. We performed meta-analyses to pool adjusted risk estimates using a random-effects model. Results Nineteen of 2053 eligible studies met

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Koh, KH, Cl Tan, and PH Chew. "Acute renal failure in severe falciparum malaria patients in an intensive care unit in Malaysia." Journal of the Royal College of Physicians of Edinburgh 36, no. 2 (2006): 107–11. https://doi.org/10.1177/1478271520063602004.

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Objectives: Identify the risk factors and the clinical impact of ARF in patients with severe falciparum malaria. Method: Intensive care unit cases of severe falciparum malaria of Sarawak General Hospital were analysed. Results: Out of 40 cases of severe falciparum malaria, 19 developed ARF. Patients with ARF were older (p=0·030), had higher AST (p=0·014), higher unconjugated bilirubin (p=0·041), and lower globulin (p=0·015). Aspartate transaminase level positively correlated with creatinine and urea level (log AST and urea: r=0·464, p=0·004; log AST and log creatinine: r=0·430, p=0·008); while

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Boadu, Kwame, and Frank Trovato. "Association of Social Class with Malaria Prevalence Among Household Heads in Ghana." Canadian Studies in Population 33, no. 2 (2006): 271. http://dx.doi.org/10.25336/p6fs67.

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This is an exploratory study that investigates the association of social class with malaria prevalence among household heads in Ghana. Data utilized is taken from the 1997 Core Welfare Indicators Questionnaire (CWIQ) survey of Ghana. The survey collected information on households covering a variety of topics including education, health, employment, household assets, household amenities, poverty predictors, and child anthropometry. A total of 14,514 households were interviewed, comprising 63 percent rural household heads and 37 percent urban household heads. The research method employed in this

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Naufal, F. Nugraha, Fauziah Nisa, Faridah Lia, and Hutagalung Jontari. "The Hemoglobin Levels and Characteristics in Malaria Endemic Region in Eastern Indonesia." Journal of Health and Medical Sciences 3, no. 1 (2020): 41–48. https://doi.org/10.31014/aior.1994.03.01.95.

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Introductions: Anemia is the most common symptoms to appear in malaria infection. Hb levels in malaria infection are one of the benchmarks to determine whether or not a patient is anemic as a predictor of the severity of infection. Malarial anemia is capable of causing severe morbidity and mortality especially in children and pregnant women infected. The most prevalent etiology of malaria in Indonesia is P. falciparum (52%) and P. vivax (38%). There is no specific study about Hb level in the community in an endemic area. Accurate clinical diagnoses are necessary to determine the local specific

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Diouf, Ibrahima, Roberto Suárez-Moreno, Belen Rodríguez-Fonseca, et al. "Oceanic Influence on Seasonal Malaria Incidence in West Africa." Weather, Climate, and Society 14, no. 1 (2022): 287–302. http://dx.doi.org/10.1175/wcas-d-20-0160.1.

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Abstract Climate variability is a key factor in driving malaria outbreaks. As shown in previous studies, climate-driven malaria modeling provides a better understanding of malaria transmission dynamics, generating malaria-related parameters validated as a reliable benchmark to assess the impact of climate on malaria. In this framework, the present study uses climate observations and reanalysis products to evaluate the predictability of malaria incidence in West Africa. Sea surface temperatures (SSTs) are shown as a skillful predictor of malaria incidence, which is derived from climate-driven s

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Awandare, Gordon A., Yamo Ouma, Collins Ouma, et al. "Role of Monocyte-Acquired Hemozoin in Suppression of Macrophage Migration Inhibitory Factor in Children with Severe Malarial Anemia." Infection and Immunity 75, no. 1 (2006): 201–10. http://dx.doi.org/10.1128/iai.01327-06.

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ABSTRACT Severe malarial anemia (SMA), caused by Plasmodium falciparum infections, is one of the leading causes of childhood mortality in sub-Saharan Africa. Although the molecular determinants of SMA are largely undefined, dysregulation in host-derived inflammatory mediators influences disease severity. Macrophage migration inhibitory factor (MIF) is an important regulator of innate inflammatory responses that has recently been shown to suppress erythropoiesis and promote pathogenesis of SMA in murine models. To examine the role of MIF in the development of childhood SMA, peripheral blood MIF

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Khan, Shiraz Jamal, Yasir Abbass, and Mumtaz Ali Marwat. "Thrombocytopenia as an Indicator of Malaria in Adult Population." Malaria Research and Treatment 2012 (July 2, 2012): 1–4. http://dx.doi.org/10.1155/2012/405981.

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Objectives. To evaluate the predictive value of thrombocytopenia in malaria. Patients and Methods. It was a prospective observational study on all febrile patients with thrombocytopenia presenting to the Medical Unit of Hayat Abad Medical Complex during November 2008 to November 2010. Results. Of the total of 228 patients with fever and thrombocytopenia, 121 patients (53%) proved to be suffering from malaria. Of them 82 patients (68%) had falciparum malaria while 39 patients (32%) had vivax infection. Of these 121 patients, platelet counts ranged between 25,000 and 150,000/dL with a mean value

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Muthui, Michelle K., Polycarp Mogeni, Kennedy Mwai, et al. "Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort." Wellcome Open Research 4 (April 5, 2019): 66. http://dx.doi.org/10.12688/wellcomeopenres.15186.1.

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Background: Interventions to block malaria transmission from humans to mosquitoes are currently in development. To be successfully implemented, key populations need to be identified where the use of these transmission-blocking and/or reducing strategies will have greatest impact. Methods: We used data from a longitudinally monitored cohort of children from Kilifi county located along the Kenyan coast collected between 1998-2016 to describe the distribution and prevalence of gametocytaemia in relation to transmission intensity, time and age. Data from 2,223 children accounting for 9,134 person-

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Muthui, Michelle K., Polycarp Mogeni, Kennedy Mwai, et al. "Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort." Wellcome Open Research 4 (May 28, 2019): 66. http://dx.doi.org/10.12688/wellcomeopenres.15186.2.

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Background:Interventions to block malaria transmission from humans to mosquitoes are currently in development. To be successfully implemented, key populations need to be identified where the use of these transmission-blocking and/or reducing strategies will have greatest impact.Methods:We used data from a longitudinally monitored cohort of children from Kilifi county located along the Kenyan coast collected between 1998-2016 to describe the distribution and prevalence of gametocytaemia in relation to transmission intensity, time and age. Data from 2,223 children accounting for 9,134 person-yea

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Omale, Ugwu I. "Knowledge, attitude, and practice of the National Guidelines for Diagnosis and Treatment of Malaria among medical doctors in Ebonyi state, Nigeria: A cross-sectional survey." PLOS ONE 16, no. 9 (2021): e0257600. http://dx.doi.org/10.1371/journal.pone.0257600.

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Background The Guidelines for Diagnosis and Treatment of Malaria are meant to guide medical practitioners to enhance optimal management of patients suspected of having malaria which is vital to malarial control and elimination. Medical doctors have the main responsibility for treating patients with malaria so there was need to evaluate the extent to which the medical doctors in Ebonyi state, Nigeria, knew, viewed, and practiced the 2015 National Guidelines for Diagnosis and Treatment of Malaria. Methods A cross-sectional survey was carried out in May, 2019 among medical doctors who were involv

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Ong'echa, John M., Gregory C. Davenport, John M. Vulule, James B. Hittner, and Douglas J. Perkins. "Identification of Inflammatory Biomarkers for Pediatric Malarial Anemia Severity Using Novel Statistical Methods." Infection and Immunity 79, no. 11 (2011): 4674–80. http://dx.doi.org/10.1128/iai.05161-11.

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ABSTRACTAreas wherePlasmodium falciparumtransmission is holoendemic are characterized by high rates of pediatric severe malarial anemia (SMA) and associated mortality. Although the etiology of SMA is complex and multifactorial, perturbations in inflammatory mediator production play an important role in the pathogenic process. As such, the current study focused on identification of inflammatory biomarkers in children with malarial anemia. Febrile children (3 to 30 months of age) presenting at Siaya District Hospital in western Kenya underwent a complete clinical and hematological evaluation. Ch

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Muriithi, Dennis, Victor Lumumba, and Mark Okongo. "A Machine Learning-Based Prediction of Malaria Occurrence in Kenya." American Journal of Theoretical and Applied Statistics 13, no. 4 (2024): 65–72. http://dx.doi.org/10.11648/j.ajtas.20241304.11.

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For many years’ malaria has been a health public concern in Kenya as well as many parts of Africa and other parts of the world. The purpose of this study is to develop and evaluate a supervised machine learning model to predict malaria occurrence (final malaria test results) in Kenya. The study investigated twelve predictor variables on the outcome variable (malaria test results), where five machine learning models namely; k-nearest neighbors, support vector machines, random forest, tree bagging, and boosting, were estimated. During the model evaluation, random forest emerged as the best overa

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Obasohan, Phillips Edomwonyi, Stephen J. Walters, Richard Jacques, and Khaled Khatab. "A Scoping Review of Selected Studies on Predictor Variables Associated with the Malaria Status among Children under Five Years in Sub-Saharan Africa." International Journal of Environmental Research and Public Health 18, no. 4 (2021): 2119. http://dx.doi.org/10.3390/ijerph18042119.

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Background/Purpose: In recent times, Sub-Saharan Africa (SSA) had been rated by the World Health Organization (WHO) as the most malaria-endemic region in the world. Evidence synthesis of the factors associated with malaria among children aged under-five in SSA is urgently needed. This would help to inform decisions that policymakers and executors in the region need to make for the effective distribution of scarce palliative resources to curb the spread of the illness. This scoping review is aimed at identifying studies that have used multivariate classical regression analysis to determine the

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Danladi, Y. K., and B. Suleiman. "Identifying Socio-Economic factors Associated with Malaria Infection in Birnin Kebbi, Nigeria." Continental J. Biological Sciences 14, no. 1 (2021): 9–15. https://doi.org/10.5281/zenodo.5595671.

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<em>Malaria has long been identified as a major cause of morbidity and mortality, in Nigeria. Data explaining the potential effect of socioeconomic variables on malaria risk, are scantly available in many places. This study was conducted to assess the effect of socioeconomic factors on the occurrence of malaria among study population in Birnin Kebbi, Nigeria. Structured questionnaires were administered to gather relevant baseline information about the study population. Blood samples were collected and tested for malaria using rapid diagnostic test kit (RTD). Persons who cannot read or write ha

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Achieng, Elsen, Vincent Otieno, and Joseph Mung'atu. "Modeling the trend of reported malaria cases in Kisumu county, Kenya." F1000Research 9 (June 12, 2020): 600. http://dx.doi.org/10.12688/f1000research.23259.1.

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Background: Although there has been an extensive scale-up of malaria interventions in Kenya, malaria infections persist at unacceptably high levels in some of the regions. Even with renewed calls to eradicate the disease through increased international donor assistance and country-specific government involvement, malaria is still a cause of worry in endemic regions. The objective of this study was to determine the factors associated with the incidence of malaria in Kisumu County over time. Methods: The study conducted secondary analysis of data from a cross-sectional survey of routinely report

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Woodcroft, Ben J., Robert Radloff, Lee M. Yeoh, et al. "An integrative bioinformatic predictor of protein sub-cellular localisation in malaria." BMC Bioinformatics 12, Suppl 11 (2011): A6. http://dx.doi.org/10.1186/1471-2105-12-s11-a6.

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Diao, Ousmane, P. A. Absil, and Mouhamadou Diallo. "Generalized Linear Models to Forecast Malaria Incidence in Three Endemic Regions of Senegal." International Journal of Environmental Research and Public Health 20, no. 13 (2023): 6303. http://dx.doi.org/10.3390/ijerph20136303.

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Affecting millions of individuals yearly, malaria is one of the most dangerous and deadly tropical diseases. It is a major global public health problem, with an alarming spread of parasite transmitted by mosquito (Anophele). Various studies have emerged that construct a mathematical and statistical model for malaria incidence forecasting. In this study, we formulate a generalized linear model based on Poisson and negative binomial regression models for forecasting malaria incidence, taking into account climatic variables (such as the monthly rainfall, average temperature, relative humidity), o

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Fernández, Nerea Castillo, Esmeralda Manzano López, Laura Castro Coca, Alejandro Moya Ruiz, and Manuel Jesús Soriano Pérez. "1900 - DIAGNÓSTICO INICIAL INCORRECTO DE MALARIA COMO PREDICTOR DE MALARIA GRAVE: ¿DEBEMOS CONCIENCIARNOS DE HACER UN DIAGNÓSTICO PRECOZ?" Revista Clínica Española 223 (November 2023): S745—S746. http://dx.doi.org/10.1016/s0014-2565(23)00949-9.

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Jegede, Feyisayo E., Tinuade I. Oyeyi, Surajudeen A. Abdulrahman, and Henry A. Mbah. "Malaria Parasite Density as a Predictor of Hematological Parameter Changes among HIV Infected Adults Attending Two Antiretroviral Treatment Clinics in Kano, Northwest Nigeria." Journal of Tropical Medicine 2020 (April 27, 2020): 1–9. http://dx.doi.org/10.1155/2020/3210585.

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Background. Despite public health significance of dual infections of human immunodeficiency virus (HIV) and malaria in developing countries like Nigeria, information on the association between malaria parasite density count (MPDC) and hematological parameter changes among HIV-infected individuals is rarely available. Objectives. To evaluate burden of HIV and malaria dual infections and assess the predictive association of MPDC with hematological parameter changes among HIV infected adults attending two antiretroviral treatment clinics in Kano, Nigeria. Methodology. This was a cross-sectional s

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Arafa, A. A. M., M. Khalil, and A. Sayed. "A Non-Integer Variable Order Mathematical Model of Human Immunodeficiency Virus and Malaria Coinfection with Time Delay." Complexity 2019 (March 19, 2019): 1–13. http://dx.doi.org/10.1155/2019/4291017.

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The purpose of this paper is to propose a variable fractional-order model with a constant time delay of the coinfection of HIV/AIDS and malaria. The proposed model describes the interaction between HIV/AIDS and malaria. This model is presented by using variable fractional-order derivative which is an extension of the constant fractional-order derivative to explain a certain pattern in the development of infection of several patients. The presented model has been solved numerically via the predictor-corrector scheme. The local and global stability conditions of the disease-free equilibrium are

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Zubair, Yasir, Muneeba Zubair, Usman Saeed, et al. "Assessment of Malaria, Anemia and Nutrition status of school-going children in the rural area of Charsadda, Pakistan." International Journal on Food, Agriculture and Natural Resources 5, no. 3 (2024): 107–11. http://dx.doi.org/10.46676/ij-fanres.v5i3.377.

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Malaria, anemia, and malnutrition are global health challenges with significant morbidity and mortality, and higher rates among children particularly in Africa. This study evaluated the prevalence and risk factors of malaria infection, anemia, and malnutrition among school-going children of Charsadda (a city of Khyber, Pakistan). A total of 400 children of aged 5-10 years were included in the study in 2023. Malaria infection was confirmed by rapid diagnostic tests. Hematocrit level was obtained using a centrifuge microhematocrit and converted to hemoglobin using standard conversion. Nutritiona

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Musa, Sani, Hauwa Umar Makarfi, Abdulhakeem Abayomi Olorukooba, Nuru Suleiman Muhammad, and Bilqis Muhammad. "Awareness, Perception and Acceptance of Malaria Vaccine among Women of the Reproductive Age Group in a rural community in Soba, Kaduna State, North-west Nigeria." Kanem Journal Medical Sciences 16, no. 1 (2022): 32–42. http://dx.doi.org/10.36020/kjms.2022.1601.004.

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ABSTRACT Introduction: Malaria vaccine is one of the novel strategies currently being evaluated for use in malaria control in children under five. Objectives: The study aimed to determine the awareness, perception and acceptance of malaria vaccine among women of the reproductive age group in a rural community in Soba Local Government Area of Kaduna State, North-West Nigeria. Methodology: It was a cross-sectional study and total population sampling was used to recruit 236 women aged between 15-49 years. The data were collected using an open data kit (ODK-1) mounted on android tablets and entere

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Machini, Beatrice, Thomas NO Achia, Jacqueline Chesang, Beatrice Amboko, Paul Mwaniki, and Hillary Kipruto. "Cross-sectional study to predict subnational levels of health workers’ knowledge about severe malaria treatment in Kenya." BMJ Open 12, no. 1 (2022): e058511. http://dx.doi.org/10.1136/bmjopen-2021-058511.

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ObjectivesThis study applied a Bayesian hierarchical ecological spatial model beyond predictor analysis to test for the best fitting spatial effects model to predict subnational levels of health workers’ knowledge of severe malaria treatment policy, artesunate dosing, and preparation.SettingCounty referral government and major faith-based hospitals across 47 counties in Kenya in 2019.Design and participantsA secondary analysis of cross-sectional survey data from 345 health workers across 89 hospitals with inpatient departments who were randomly selected and interviewed.Outcome measuresThree or

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Morenikeji, Olanrewaju B., Jessica L. Metelski, Megan E. Hawkes, et al. "CD209 and Not CD28 or STAT6 Polymorphism Mediates Clinical Malaria and Parasitemia among Children from Nigeria." Microorganisms 8, no. 2 (2020): 158. http://dx.doi.org/10.3390/microorganisms8020158.

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Malaria remains a significant disease, causing epic health problems and challenges all over the world, especially in sub-Saharan Africa. CD209 and CD28 genes act as co-stimulators and regulators of the immune system, while the STAT6 gene has been reported to mediate cytokine-induced responses. Single nucleotide polymorphisms of these genes might lead to differential disease susceptibility among populations at risk for malaria, due to alterations in the immune response. We aim to identify key drivers of the immune response to malaria infection among the three SNPs: CD209 (rs4804803), CD28 (rs35

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Oluyide, O. P., O. O. Odu, S. K. Salami, et al. "The predictors of ownership and utilization of Long-Lasting Insecticidal Nets among caregivers of under-five children in Ekiti State, South-West, Nigeria." Research Journal of Health Sciences 12, no. 4 (2024): 309–21. http://dx.doi.org/10.4314/rejhs.v12i4.8.

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Background - Malaria is a life-threatening disease associated with a high level of morbidity and mortality in sub-Saharan Africa especially among children under five years of age. Long-lasting insecticidal Nets (LLINs) ownership and utilization are some of the proven interventions to reduce the burden of the disease. This paper aims to assess and compare the predictors of ownership and utilization of LLINs among caregivers of under-five children living in urban and rural settlements in Ekiti State, Nigeria. - This was a cross- sectional comparative study among 800 under-five caregivers. A mult

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Flora, Rostika, Mukni Mukni, Bina Melvia Girsang та Sigit Purwanto. "Tumor Necrosis Factor-α sebagai Prediktor Terjadinya Anemia pada Ibu Hamil di Wilayah Endemis Malaria". Kesmas: National Public Health Journal 9, № 3 (2015): 288. http://dx.doi.org/10.21109/kesmas.v9i3.695.

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Ibu hamil yang berada di daerah endemis malaria sangat rentan terhadap infeksi malaria selama kehamilan. Gejala malaria pada kelompok ini sering asimptomatik atau bahkan tidak terdeteksi sama sekali karena adanya efek imunitas protektif melalui infeksi yang berulang. Adanya peningkatan kadar tumor necrosis factor-alpha (TNF-α) dapat dijadikan indikator terjadinya infeksi malaria. TNF-α berperan penting dalam respons imun pada malaria akut yang menghambat terjadinya eritropoesis. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar TNF-α dengan kejadian anemia pada ibu hamil didaerah

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Ladi-Akinyemi, Temitope 'Wunmi, Babatunde Oladipupo Ladi-Akinyemi, Adedoyin Oyeyimika Ogunyemi, and Frances Ademola Oluwole. "A rural-urban comparison of ownership and utilization of Long-Lasting Insecticide Treated Nets among pregnant women in Ogun State Nigeria." Annals of Health Research 5, no. 1 (2019): 36–50. http://dx.doi.org/10.30442/ahr.0501-5-35.

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Background: The use of Long-Lasting Insecticide Treated Nets (LLINs) in Africa increased mean birth weight by 55g, reduced the incidence of low birth weight by 23% and decreased miscarriages/stillbirths by 33%. However, the benefit of the LLINs may be limited by the rate of ownership and utilization by pregnant women. Objective: To determine and compare the ownership and utilization of LLINs among pregnant women in urban and rural areas of Ogun State. Methods: A community-based comparative cross-sectional study on 72 and 74 pregnant women living in urban and rural areas, respectively of Ogun S

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Magaji, Auwal, Zinat Mahmud, Adamu Yakubu, Rilwanu Salihu Maradun, Salim Aminu, and Sabiu Aminu. "Epidemiology of Malaria in Bauchi North, Bauchi State Nigeria: Prevalence and Determinants of the Infection." UMYU Scientifica 4, no. 1 (2025): 250–59. https://doi.org/10.56919/usci.2541.025.

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Study’s Excerpt:• The study assessed malaria prevalence and risk factors in Bauchi North, Bauchi State, Nigeria.• Microscopy detected the parasite, while structured questionnaires identified infection determinants.• Results showed a high malaria burden with variations by age and socioeconomic status.• Findings highlight the need for public health interventions targeting high-risk, vulnerable groups.• Findings can guide policymakers in malaria treatment, control, and prevention efforts.Full Abstract:Malaria remains a leading public health concern globally, particularly in sub-Saharan Africa, wi

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Tovar Acero, Catalina, Javier Ramírez-Montoya, María Camila Velasco та ін. "IL-4, IL-10, CCL2 and TGF-β as potential biomarkers for severity in Plasmodium vivax malaria". PLOS Neglected Tropical Diseases 16, № 9 (2022): e0010798. http://dx.doi.org/10.1371/journal.pntd.0010798.

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Cytokines and chemokines are immune response molecules that display diverse functions, such as inflammation and immune regulation. In Plasmodium vivax infections, the uncontrolled production of these molecules is thought to contribute to pathogenesis and has been proposed as a possible predictor for disease complications. The objective of this study was to evaluate the cytokine profile of P. vivax malaria patients with different clinical outcomes to identify possible immune biomarkers for severe P. vivax malaria. The study included patients with non-severe (n = 56), or severe (n = 50) P. vivax

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Vadas, P., TE Taylor, and L. Chimsuku. "INCREASED SERUM PHOSPHOLIPASE A2 ACTIVITY IN MALAWIAN CHILDREN WITH FALCIPARUM MALARIA." Pediatrics 96, no. 1 (1995): 125. http://dx.doi.org/10.1542/peds.96.1.125.

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Malaria is a multisystem disease with a mortality rate of 5 to 30% even with optimal treatment. Earlier studies have shown increased circulating levels of TNF in the plasma of patients as an independent predictor of severe or fatal disease. TNF has already been shown to facilitate the release of proinflammatory enzyme phospholipase A2 from various cells in vitro. Because both TNF and PLA2 are increased in patients with septicemia and because TNF levels are already shown to be increased in patients with malaria, the authors studied the relationship between TNF levels, severity of disease, and P

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Praditia, Rahmat Kevin, Dian Agustina, and Dyah Setyo Rini. "ANALISIS JUMLAH KASUS MALARIA DI WILAYAH SUMATERA MENGGUNAKAN GEOGRAPHICALLY WEIGHTED ZERO-INFLATED POISSON REGRESSION (GWZIPR)." Indonesian Journal of Statistics and Its Applications 4, no. 4 (2020): 638–48. http://dx.doi.org/10.29244/ijsa.v4i4.716.

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A method that can be used if there is a spatial factor and if overdispersion happens in a count data is Geographically Weighted Zero-Inflated Poisson Regression (GWZIPR). This research aimed to analyze the number of malaria cases in every regency/city of Sumatra Land using the GWZIPR method and distribution mapping of factors affecting the number of malaria cases in Sumatra Land. Data involved in this research was the number of malaria cases as the response variable and the predictor variable as a percentage of households that have access to proper sanitation, a percentage of households that h

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Okoro, Roland Nnaemeka, and Muslim Olakunle Jamiu. "The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria." Journal of Tropical Medicine 2018 (2018): 1–6. http://dx.doi.org/10.1155/2018/2025858.

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In 2005, Nigeria changed its antimalarial drug policy to Artemisinin-based Combination Therapies (ACTs) for the treatment of malaria infection, and it is imperative for prescribers to strictly comply with this guideline to harmonize malaria management practices within the country. This study aims to evaluate prescribers’ adherence with the National Antimalarial Treatment Guideline (NATG) in the treatment of malaria infections and to describe the determinants of antimalarial drugs coprescription with antibiotics at a tertiary hospital in Nigeria. A cross-sectional, retrospective study of antima

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