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Journal articles on the topic 'Preeclampsia with severe features'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Akter, Halima, M. Tofazzel Hossain, and Shirin Shabnam. "The role of maternal serum homocysteine level in early onset preeclampsia for prediction of severity of disease." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 10 (2024): 2641–48. http://dx.doi.org/10.18203/2320-1770.ijrcog20242790.

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Background: This study was conducted to observe the relationship between high serum homocysteine levels and preeclampsia with severe features among preeclamptic pregnant women of 20-34 weeks of gestation. Method: This study was a hospital based a prospective cohort study and was conducted in Department of Obstetrics and Gynaecology in Dhaka Medical College. A total of 110 preeclamptic pregnant women of 20-34 weeks of gestational age were taken and data were collected after taking an informed written consent. After diagnosis of preeclampsia, I gave them some investigations like CBC, SGPT, S. Cr

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Savitsky, Leah M., Suchitra Chandrasekaran, and Catherine Albright. "Preeclampsia With Severe Features." Obstetrics & Gynecology 135 (May 2020): 131S. http://dx.doi.org/10.1097/01.aog.0000664660.61533.04.

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Endres, Kodi M., Catherine M. Roberts, Xinying Fang, Shouhao Zhou, Tonya S. Wright, and Conrad Krawiec. "Impact of hyponatremia in preeclamptic patients with severe features." PLOS ONE 19, no. 7 (2024): e0302019. http://dx.doi.org/10.1371/journal.pone.0302019.

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Hyponatremia, though common in women with preeclampsia, has not been well studied. Our primary objectives are to assess the clinical characteristics and emergency therapy applied to subjects diagnosed with preeclampsia. We hypothesize that hyponatremia present in preeclamptic patients with severe features is associated with greater use of emergency hypertensives, antenatal steroids, and cesarean delivery. This is a retrospective descriptive study utilizing an electronic health record database (TriNetX ®). We collected and evaluated the following data of subjects aged 15 to 54 years with preecl

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Endres, Kodi, Catherine M. Roberts, Conrad Krawiec, Xinying Fang, Tonya Wright, and Shouhao Zhou. "Effect of Hyponatremia in Preeclamptic Patients With Severe Features [ID 2683491]." Obstetrics & Gynecology 143, no. 5S (2024): 35S. http://dx.doi.org/10.1097/01.aog.0001013408.91489.6e.

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INTRODUCTION: Hyponatremia, although common in expectant women with preeclampsia, has not been well studied in a multicenter fashion, and it is unknown whether it is associated with adverse events related to severe preeclampsia. Our primary objectives are to assess the clinical characteristics and emergency therapy applied to participants diagnosed with preeclampsia. We hypothesize that hyponatremia present in preeclamptic patients with severe features is associated with greater use of emergency hypertensives, antenatal steroids, and cesarean delivery. METHODS: This is a retrospective cohort s

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Aktar, Mossa Nupur, Zakia Sultana, Marfoonnahar Smriti, et al. "Comparison between Highly Sensitive C - Reactive Protein in Subjects with Preeclampsia with Severe Features and Preeclampsia without Severe Features." Global Academic Journal of Medical Sciences 6, no. 02 (2024): 76–82. http://dx.doi.org/10.36348/gajms.2024.v06i02.006.

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Background: Preeclampsia (PE) develops in 4-5% of pregnancies in humans. It appears after 20 weeks of gestation and is defined by increased blood pressure and proteinuria. When convulsions occur or the hemolysis, high liver enzymes, and low platelet count (HELLP) condition materializes, PE can lead to eclampsia. It is well recognized that eclampsia and HELLP syndrome are linked to serious side effects include liver hemorrhage, lung edema, brain hemorrhage, and renal failure. Objective: The aim of this study is to compare between highly sensitive c- reactive protein in subjects with preeclampsi

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Akhter, Najneen, Anisa Begum, Most Tahera Akhter Moni, et al. "The Outcome of Preeclampsia with Severe Features." Dinajpur Medical College Journal 18, no. 01 (2025): 54–66. https://doi.org/10.69861/djmcj2025v18i1s9.

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Abstract Background: Preeclampsia is a critical pregnancy-related condition linked to high maternal and fetal mortality rates, with rising morbidity and mortality despite medical advancements. Objective: This study aimed to assess outcomes in patients with severe preeclampsia features at a tertiary care hospital. Methods: Conducted as a cross-sectional study over six months at the Department of Gynecology & Obstetrics, Rangpur Medical College Hospital, this research involved 100 participants meeting specific criteria for severe preeclampsia. Data on demographics, maternal, and fetal outcom

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Akter, Dr Asma, Dr Fatema Rahman, Dr Rokon Ud Dowla, et al. "Association of D-Dimer with Severity of Preeclampsia and Their Feto-Maternal Outcome." Scholars International Journal of Obstetrics and Gynecology 7, no. 12 (2024): 645–57. https://doi.org/10.36348/sijog.2024.v07i12.010.

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Background: Preeclampsia (PE) affects 2-8% of pregnancies worldwide, leading to maternal and fetal complications such as abruptio placentae, renal failure, and HELLP syndrome. Objective: To investigate the association between plasma D-dimer levels and the severity of preeclampsia, along with its impact on fetomaternal outcomes. Methods: A case-control study was conducted at Dhaka Medical College Hospital from June 2021 to May 2022, enrolling 100 preeclamptic patients (50 with severe features and 50 without severe features). Participants were between 29-40 weeks of gestation. Exclusion criteria

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Wulandari, Eka Suci, Ernawati Ernawati, and Djohar Nuswantoro. "RISK FACTORS OF PREECLAMPSIA WITH SEVERE FEATURES AND ITS COMPLICATIONS." Indonesian Midwifery and Health Sciences Journal 5, no. 1 (2021): 29. http://dx.doi.org/10.20473/imhsj.v5i1.2021.29-37.

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Abstract.Background : The maternal mortality rate in Indonesia is dominated by preeclampsia as the second highest cause after bleeding. Several predictors can be categorized as risk factors that can be used to increase alertness in the care of pregnant women with severe preeclampsia to avoid complications. The purpose of this study was to study the relationship between risk factors for severe preeclampsia and its complications. Methods: This study used an observational analytic method with a case control design. The sampling technique is simple random sampling. The number of samples in this st

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Parrales-Bravo, Franklin, Rosangela Caicedo-Quiroz, Leonel Vasquez-Cevallos, et al. "Supporting the Characterization of Preeclampsia Patients Through Descriptive and Clustering Analysis." Electronics 13, no. 23 (2024): 4854. https://doi.org/10.3390/electronics13234854.

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One of the most common causes of maternal death during pregnancy is preeclampsia. A deeper understanding of the patient’s features can aid in the hospital’s clinical care distribution. However, at the IESS Los Ceibos Hospital, these types of studies have not been carried out for preeclampsia. Therefore, in this work, we describe the application of descriptive and clustering analysis to characterize preeclamptic patients. Preeclamptic patients treated at the IESS Los Ceibos Hospital in Guayaquil comprised the dataset used in this study. Descriptive and clustering analysis allowed us to find tha

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Kivioja, Anna, Elli Toivonen, Jaakko Tyrmi, et al. "Increased Risk of Preeclampsia in Women With a Genetic Predisposition to Elevated Blood Pressure." Hypertension 79, no. 9 (2022): 2008–15. http://dx.doi.org/10.1161/hypertensionaha.122.18996.

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Background: Preeclampsia causes significant maternal and perinatal morbidity. Genetic factors seem to affect the onset of the disease. We aimed to investigate whether the polygenic risk score for blood pressure (BP; BP-PRS) is associated with preeclampsia, its subtypes, and BP values during pregnancy. Methods: The analyses were performed in the FINNPEC study (Finnish Genetics of Pre-Eclampsia Consortium) cohort of 1514 preeclamptic and 983 control women. In a case-control setting, the data were divided into percentiles to compare women with high BP-PRS (HBP-PRS; >95th percentile) or low BP-

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Özkavak, Osman Onur, and Dilek Sahin. "The Utility of Albumin-Bilirubin Score as a Prognostic Marker in Preeclampsia." Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 22, no. 1 (2025): 19–25. https://doi.org/10.38136/jgon.1629392.

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Aims: To evaluate the utility of the albumin bilirubin (ALBI) score as a liver function test and prognostic marker in patients with preeclampsia. Materials and Methods: A total of 374 patients were enrolled in the study (148 preeclampsia without severe features, 112 preeclampsia with severe features, 114 controls). The study compared clinical and demographic features, laboratory findings and ALBI scores between the three groups. Also, receiver operating curve (ROC) analysis was used for the estimation of the predictive value of the ALBI score for the severity of preeclampsia and maternal/neona

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Livinus Nnanyereugo Onah, Malachy Nwaeze Ezenwaeze, and Chibugo Ndidiamaka Nwankwo. "Pre-eclampsia: A comprehensive review of pathophysiology, clinical features, prevention and management." World Journal of Advanced Pharmaceutical and Medical Research 9, no. 1 (2025): 012–19. https://doi.org/10.53346/wjapmr.2025.9.1.0030.

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Background: Preeclampsia is a hypertensive disorder of pregnancy characterized by new-onset hypertension and proteinuria or end-organ dysfunction after 20 weeks of gestation. It remains a leading cause of maternal and perinatal morbidity and mortality worldwide. Objective: To provide a concise overview of the pathophysiology, clinical features, prevention, and current management strategies for preeclampsia. Methods: A narrative review of recent literature on preeclampsia was conducted, focusing on diagnostic criteria, risk factors, and therapeutic approaches. Results: Abnormal placentation, sy

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Barda, Sivan, Yochai Yoeli, Nitzan Stav, et al. "Factors Associated with Progression to Preeclampsia with Severe Features in Pregnancies Complicated by Mild Hypertensive Disorders." Journal of Clinical Medicine 12, no. 22 (2023): 7022. http://dx.doi.org/10.3390/jcm12227022.

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In this retrospective cohort study, we aimed to investigate the variables associated with progression to preeclampsia with severe features in parturients already diagnosed with mild hypertensive disorders of pregnancy. The study was conducted in a single university-affiliated medical center between 2018 and 2020. All women admitted due to hypertensive disorders were included. Data collected was compared between parturients who progressed and did not progress to preeclampsia with severe features. Among 359 women presenting without severe features, 18 (5%) developed severe features, delivered sm

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Zaripova D.Ya. "Features Changes Hemodinamic Liver Easy Preeclampsia." International Journal of Human Computing Studies 6, no. 3 (2024): 139–41. https://doi.org/10.31149/ijhcs.v5i12.5023.

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Examine the systemic circulation of the liver and its role in the predicting of preeclampsia. We studied 100 pregnant women with mild preeclampsia (II group), and 50 pregnant women with physiological pregnancy control group (I group), 50 pregnant women with severe PE (III group). Comprehensive ultrasound and Doppler blood flow study was performed, ultrasound scanner Sono-scape SSI 5000 (China model) equipped with Convex probe (3.5 MHz) provided with a pulsed Doppler unit and wave function of the DRC. Examined blood flow in arteries and veins of the liver (liv A, liv V, Col V). Blood flow in th

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Gilboa, Itamar, Michael Kupferminc, Anat Schwartz, et al. "The Association between Advanced Maternal Age and the Manifestations of Preeclampsia with Severe Features." Journal of Clinical Medicine 12, no. 20 (2023): 6545. http://dx.doi.org/10.3390/jcm12206545.

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This retrospective cohort study aimed to explore the association between advanced maternal age and the clinical manifestations as well as laboratory parameters of preeclampsia with severe features. This study included 452 patients who were diagnosed with preeclampsia with severe features. The clinical and laboratorial characteristics of patients with preeclampsia with severe features aged ≥40 years old (study group) were compared to those of patients aged <40 years old (control group). Multivariant analysis was applied to assess the association between advanced maternal age and the manifest

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Sathiya, Ramasamy, Jayanthi Rajendran, and Saravanan Sumathi. "COVID-19 and Preeclampsia: Overlapping Features in Pregnancy." Rambam Maimonides Medical Journal 13, no. 1 (2022): e0007. http://dx.doi.org/10.5041/rmmj.10464.

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Coronavirus disease 2019 (COVID-19) is a global respiratory disease with unique features that have placed all medical professionals in an alarming situation. Preeclampsia is a hypertensive disorder of pregnancy affecting 8%–10% of India’s pregnant population. Assuming that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters host cells through the angiotensin-converting enzyme 2 (ACE2) receptor, the resulting symptoms are due to vasoconstriction, caused by disturbances in the renin–angiotensin system (RAS). Other features of preeclampsia include endothelial dysfunction due to pl

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Kesty, Cindy, Wim T. Pangemanan, A. Kurdi Syamsuri, et al. "Update Manajemen Preeklamsia dengan Komplikasi Berat (Eklamsia, Edema Paru, Sindrom HELLP)." Indonesian Journal of Obstetrics & Gynecology Science 6, no. 1 (2023): 7–19. http://dx.doi.org/10.24198/obgynia.v6n1.402.

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Tujuan: Seiring dengan bertambahnya insidensi preeklamsia dengan komplikasi berat, manajemen yang adekuat diperlukan. Penulisan artikel ini bertujuan untuk memaparkan update manajemen preeklamsia dengan komplikasi berat (eklamsia, edema paru, dan sindrom HELLP). Metode: Tinjauan pustaka (literature review) dengan menggunakan 15 referensi antara tahun 2011–2020. Hasil: Manajemen preeklamsia dengan komplikasi berat membutuhkan pendekatan multidisiplin, medikamentosa (kalsium 1,5–2 gram/hari; aspirin dosis rendah 75–150 mg/hari; MgSO4 dengan dosis awal 4–6 gram IV dan pemeliharaan 1-2 gram/jam hi

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EL-Zoghby, Ibrahim, Irene Fathy, Fatma Atta, and Samir Elhadidy Tawfik Elhadidy. "Ultrasonographic measurement of optic nerve sheath diameter as a predictor of severity of preeclampsia: a cross-sectional analytic study." Research and Opinion in Anesthesia & Intensive Care 12, no. 2 (2025): 126–32. https://doi.org/10.4103/roaic.roaic_20_24.

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Background An increase in intracranial pressure (ICP) is one of the consequences of preeclampsia. Changes in the optic nerve sheath diameter (ONSD) are an important demonstration of increased ICP. Our study aimed to investigate the value of ultrasound-measured ONSD in detecting brain edema in preeclamptic patients when compared to computed tomography (CT) brain and predicting the severity of preeclampsia. Patients and methods We studied 60 patients with preeclampsia at Kasr Al-Ainy hospitals in Egypt from October 2022 to February 2023. The patients were divided into two equal groups according

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Rifqiya Faiza, Mita Maulida, Novia Fransiska Ngo, and Ika Fikriah. "HUBUNGAN PREEKLAMPSIA BERAT DENGAN KOMPLIKASI PADA JANIN DI RSUD ABDUL 2 WAHAB SJAHRANIE SAMARINDA 3 TAHUN 2017-2018." Jurnal Kebidanan Mutiara Mahakam 7, no. 2 (2019): 74–84. http://dx.doi.org/10.36998/jkmm.v7i2.59.

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Preeclampsia defined as new onset of hypertension and proteinuria after 20 weeks of gestation. Preeclampsia is one of the three main causes of maternal mortality with an incidence of 128,273 each year or around 5.3% in Indonesia. Preeclampsia is classified as preeclampsia without severe features and severe preeclampsia. Severe preeclampsia can be a problem, both in the mother and the fetus due to vascular vasospasm. If uteroplacental blood flow to the fetus is limited, the fetus can be born under low birth weight (LBW), preterm birth, intra uterine fetal death, and low Apgar score. The aim of

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Jarvis, Elizabeth, and Adam Morton. "Adrenal cortical carcinoma mimicking early severe preeclampsia." Obstetric Medicine 7, no. 1 (2013): 45–47. http://dx.doi.org/10.1177/1753495x13502958.

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Preeclampsia is a common disorder in pregnancy and may affect multiple maternal and foetal organ systems. Less common disorders with similar features may imitate preeclampsia though require different management strategies and with different prognostic implications for mother and baby. We present a case of a pregnant woman who developed severe hypertension and proteinuria in pregnancy. The early onset of these changes prompted investigation for causes other than preeclampsia, leading to a diagnosis of Cushing’s syndrome due to stage III adrenocortical cancer. The changes in management strategy,

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Sampson, Rachael, Sidney Davis, Roger Wong, Nicholas Baranco, and Robert K. Silverman. "Pulse Pressure as a Hemodynamic Parameter in Preeclampsia with Severe Features Accompanied by Fetal Growth Restriction." Journal of Clinical Medicine 13, no. 15 (2024): 4318. http://dx.doi.org/10.3390/jcm13154318.

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Background: Modern management of preeclampsia can be optimized by tailoring the targeted treatment of hypertension to an individual’s hemodynamic profile. Growing evidence suggests different phenotypes of preeclampsia, including those with a hyperdynamic profile and those complicated by uteroplacental insufficiency. Fetal growth restriction (FGR) is believed to be a result of uteroplacental insufficiency. There is a paucity of research examining the characteristics of patients with severe preeclampsia who do and who do not develop FGR. We aimed to elucidate which hemodynamic parameters differe

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Ilikannu, Samuel O., Precious Agenu, Sunday E. Jombo, et al. "Risk factors, phenotypic-pattern and feto-maternal outcomes of preeclampsia with severe features in a low-resource setting: a prospective study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 14, no. 6 (2025): 1684–90. https://doi.org/10.18203/2320-1770.ijrcog20251551.

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Background: Preeclampsia is exclusive to pregnancy and one of the leading causes of maternal and perinatal morbidity and mortality globally. This study aims to assess the prevalence, risk factors, phenotypic pattern and feto-maternal outcomes among women managed for preeclampsia with severe features at the Federal Medical Center Asaba. Methods: Women managed for preeclampsia with severe features between 1st June 2022 and, 31st January 2023 were recruited and relevant data extracted and entered into a standardized proforma which was subsequently analyzed using the SPSS version 26. Categorical v

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Pierce-Williams, Rebecca A. M., and Robert M. Ehsanipoor. "Expectant Management of Early-Onset Preeclampsia With Severe Features." Topics in Obstetrics & Gynecology 38, no. 14 (2018): 1–7. http://dx.doi.org/10.1097/01.pgo.0000546678.22841.b5.

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Aziz, Aryani, and Uqbah Abdul Salam. "Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care." Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) 14, no. 1 (2025): 6–11. https://doi.org/10.14710/dmj.v14i1.46584.

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Background: Preeclampsia is a condition characterized by new-onset hypertension during pregnancy, which can lead to various complications for both the mother and baby. It is categorized into early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE) based on the timing of onset, each having distinct pathophysiologies and complications. Objective: This study aims to evaluate maternal and perinatal outcomes in patients with early and late-onset severe preeclampsia. Methods: An analytic observational study with a cross-sectional design was conducted at a secondary healthcare facility. T

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Tolcher, Mary C., Alison N. Goulding, Josef Jackson, Felixnando Rubio, Jeevitha Patil, and Steven Clark. "615 Expectant management of preeclampsia with severe features: clinical outcomes based on severe features at diagnosis." American Journal of Obstetrics and Gynecology 230, no. 1 (2024): S333. http://dx.doi.org/10.1016/j.ajog.2023.11.640.

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Hillman, Michelle, Lyba Khan, Jenna Patel, Kylie C. Long, Katherine Leung, and Heidi K. Leftwich. "Effect of SARS-CoV-2 Infection on Preeclampsia Rates in a Single Academic Center [ID 2683570]." Obstetrics & Gynecology 143, no. 5S (2024): 6S. http://dx.doi.org/10.1097/01.aog.0001012920.57547.2a.

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INTRODUCTION: Given the rise in preeclampsia during the COVID-19 pandemic, we aim to describe the effect of SARS-CoV-2 positivity during pregnancy on rates of preeclampsia with and without severe features. METHODS: This was an IRB-approved retrospective cohort study of patients receiving prenatal care and delivering at our academic hospital from January 1, 2019 to December 30, 2022. Primary outcomes were rates of preeclampsia and severe preeclampsia among those with and without SARS-CoV-2 infection during pregnancy. The secondary outcomes were placental pathology. RESULTS: Six thousand three h

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Febres-Cordero, Daniela A., and Brett C. Young. "Hypertensive Disorders of Pregnancy." NeoReviews 22, no. 11 (2021): e760-e766. http://dx.doi.org/10.1542/neo.22-11-e760.

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Preeclampsia is a hypertensive disorder of pregnancy that is a leading cause of maternal and perinatal morbidity and mortality. The condition presents heterogeneously at varying gestational ages. Primary prevention for preeclampsia with low-dose aspirin is recommended for patients with clinical risk factors. Despite extensive research, there is no clearly defined pathophysiology for preeclampsia or treatment for preeclampsia besides delivery of the placenta. Delivery of patients with preeclampsia without severe features is indicated in the early term period at 37 weeks’ gestation and sooner if

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Schoen, Corina N., Lindsay Odell, Sindy C. Moreno, Nora Graham, Lauren Cooper, and Amanda Roman. "Predictors of Progression of Preterm Preeclampsia Without Severe Features to Severe Disease [26H]." Obstetrics & Gynecology 127 (May 2016): 73S. http://dx.doi.org/10.1097/01.aog.0000483703.28878.c2.

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Dale, Andrew G., Bradley D. Holbrook, Lauren Sobel, and Valerie J. Rappaport. "Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features." Case Reports in Obstetrics and Gynecology 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/6061313.

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Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus.Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyro

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Isaeva, E. V., and V. T. Ryskeldieva. "Caesarean section in severe preeclampsia: features of early neonatal adaptation." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 66, no. 4 (2021): 39–44. http://dx.doi.org/10.21508/1027-4065-2021-66-4-9-44.

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Objective. To study the course of early neonatal adaptation depending on the anesthetic aid in abdominaldelivery of pregnant women with severe preeclampsia. Characteristic o fchildren and research methods. Thea uthorscarried outaprospective cohort study o f342 childrenborn from mothers with severepreeclampsia. The children were grouped according to their gestationalage. The author sanalyzed perinatallosse sand assessed general condition according to the Apgarscaleat the 1st and 5th minutes of life, aswell as the neurological status of newborns according to the NACS scale at the 15thminute of l

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Tzur, Yossi, Eli Rimon, Gil Geva, Jacky Herzlich, and Michael J. Kupferminc. "Progression from isolated gestational proteinuria to preeclampsia with severe features." Acta Obstetricia et Gynecologica Scandinavica 100, no. 9 (2021): 1620–26. http://dx.doi.org/10.1111/aogs.14198.

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Inta, Anuchit, Theera Tongsong, and Kasemsri Srisupundit. "Pregnancy Outcomes of Conservative Management in Preeclampsia with Severe Features." Journal of Clinical Medicine 12, no. 19 (2023): 6360. http://dx.doi.org/10.3390/jcm12196360.

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Objective: To study the pregnancy outcomes of conservative treatment for preeclampsia with severe features. Methods: A retrospective study was conducted on pregnancies with preeclampsia with severe features at gestational age 23–34 weeks and that received conservative management at Chiang Mai University Hospital between January 2014 and August 2020. The women were divided into two groups: (1) pregnancy prolongation of at least 48 h and (2) pregnancy prolongation of less than 48 h. Results: Of the 100 recruited pregnancies, the median gestational age was 29 weeks (range 23–34). Of these, 65 cas

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Stanek, Jerzy. "Histological Features of Shallow Placental Implantation Unify Early-Onset and Late-Onset Preeclampsia." Pediatric and Developmental Pathology 22, no. 2 (2018): 112–22. http://dx.doi.org/10.1177/1093526618803759.

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Preeclampsia is distinguishable from other hypertensive conditions of pregnancy by its high rates of decidual arteriopathy, the uterine type of chronic hypoxic placental injury, the occurrence of villous infarctions, and clusters of multinucleate trophoblasts in the maternal floor. To retrospectively study the clinical and placental phenotypes of 230 women with early-onset preeclampsia, 261 women with late-onset preeclampsia, and 5059 women without hypertension in pregnancy (comparative group), 24 clinical and 46 placental phenotypes were statistically compared (analysis of variance, χ2 with B

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Archana A, Sumitha A, Sathiyapriya V, and Ursula Sampson. "An angiogenic marker for early prediction of preeclampsia." Asian Journal of Medical Sciences 13, no. 8 (2022): 195–201. http://dx.doi.org/10.3126/ajms.v13i8.44566.

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Background: Preeclampsia is a pregnancy-specific disease associated with a high incidence of maternal and fetal morbidity and mortality with classical features of hypertension, proteinuria, and edema. Aims and Objectives: The aims of the study were to study the angiogenic marker for the early predicting of preeclampsia. Materials and Methods: Blood samples were collected from 75 healthy singleton pregnant women from 19 to 29 years between 12 and 16 weeks of gestation with no underlying medical illness. The serum soluble endoglin (sEng) level and serum uric acid levels were estimated. Patients

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Volkov, V. G., and Leyla M. Badalova. "FEATURES OF PREGNANCY IN NULLIPAROUS WITH EARLY PREECLAMPSIA." V.F.Snegirev Archives of Obstetrics and Gynecology 6, no. 3 (2019): 145–50. http://dx.doi.org/10.18821/2313-8726-2019-6-3-145-150.

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Objective - to study the characteristics of the course of pregnancy, maternal and perinatal outcomes in nulliparous with early preeclampsia. Methods. 127 nulliparas were included in the prospective case-control study. Two groups were formed: 1st (n = 27) - pregnant with early preeclampsia, 2nd (n = 100) - pregnant without preeclampsia. Mild preeclampsia occurred in 21 (77,8%) and severe in 6 (22,2%). Results. A significant difference was detected in the I trimester, which was expressed in differently directed changes in the indices of ß-hCG and PAPP-A. Violation of hemodynamic parameters was n

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Ventskovskaya, I. B., A. V. Aksonova, and N. M. Lagoda. "Morphological features of the placenta in preeclampsia according histochemistry." HEALTH OF WOMAN, no. 6(112) (July 29, 2016): 73–76. http://dx.doi.org/10.15574/hw.2016.112.73.

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One of the important stages in analyzing the causes of complications of pregnancy and childbirth, particularly preeclampsia, is considered to be a natural morphological study of the placenta. The main direction of research is to identify morphological of diagnostic and prognostic criteria of preeclampsia in general, and special lesions of structures of the placenta in particular. The objective: to study the morphological features of the placenta in pregnancy complicated by preeclampsia varying severity according histochemistry and prediction of the potential cardiovascular risks in the future.

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Grover, Suparna, and Ajay Chhabra. "Severe preeclampsia and eclampsia: adverse obstetric outcomes and prognostic factors." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 8 (2021): 3005. http://dx.doi.org/10.18203/2320-1770.ijrcog20212791.

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Background: Hypertensive disorders of pregnancy are globally a threat to maternal and fetal outcomes. Despite massive efforts worldwide, these disorders continue to be a major adverse influence on the health goals especially in developing countries. The aim of the study was to measure the impact of hypertensive disorders of pregnancy in its most severe form on maternal and fetal outcomes in our region along with the important prognostic factors. The objective of this study was to investigate the maternal and fetal outcome in cases of severe preeclampsia and to evaluate the risk factors and com

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Amin, Ahmed F., Hisham Abou-Taleb, Mustafa Gamal, Marwa M. Thabet, Nashwa Azoz, and Ahmed M. Abbas. "Evaluation of Podocalyxin level in pre-eclampsia with severe features' patients: a cross-sectional study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 8 (2019): 3255. http://dx.doi.org/10.18203/2320-1770.ijrcog20193545.

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Background: This study aims to evaluate the level of podocalyxin (PCX) in preeclampsia with severe features patients and correlate it with the results of laboratory tests.Methods: The current study was a cross-sectional study conducted in Assiut Women Health Hospital between April and October 2018. The study included 60 patients divided into two groups; Group (A): 30 patients diagnosed to have preeclampsia with severe features and Group (B): 30 patients as normal control group. Complete laboratory investigations with measurements of the PCX level was performed for all study participants.Result

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Aktar, Mossa Nupur, Zakia Sultana, Marfoonnahar Smriti, et al. "High Sensitivity C-Reactive Protein as an Independent Risk Factor for Preeclampsia with Severe Features." Scholars International Journal of Obstetrics and Gynecology 7, no. 04 (2024): 181–86. http://dx.doi.org/10.36348/sijog.2024.v07i04.006.

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Background: One of the most dangerous complications of pregnancy and a major contributor to maternal and perinatal morbidity and death is preeclampsia. The goal of the current study was to measure the level of inflammation in severe preeclampsia by measuring serum high-sensitive C-reactive protein (hs-CRP) and establishing a relationship between hs-CRP and blood pressure. Objective: The aim of this study is to evaluate the impact high sensitivity C-reactive protein as an independent risk factor for preeclampsia with severe features. Methods: The cross-sectional study was carried out in the Dep

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Sachan, Rekha, Pushpa Lata Sachan, Nazrana Ghayyur, Munna Lal Patel, and Wahid Ali. "Diagnostic Accuracy of Serum Glycosylated Fibronectin in Prediction of Preeclampsia: A Nested Case–Control Study." Annals of African Medicine 23, no. 2 (2024): 169–75. http://dx.doi.org/10.4103/aam.aam_81_23.

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Background: Preeclampsia is a life-threatening complication of pregnancy that occurs in approximately 7% of all pregnancies. In India, the incidence of preeclampsia is 8%–10% and the prevalence is 5.4%, whereas the prevalence of hypertensive disorders of pregnancy is 7.8%. Aim and Objectives: This study was aimed at evaluating the diagnostic accuracy of serum glycosylated fibronectin (S. GlyFn) in the prediction of preeclampsia. Methods: A nested case–control study was carried out for 16 months in the department of obstetrics and gynecology. A total of 240 women were recruited and followed aft

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Zahan, Akhter, Md Nazrul Islam, Netay Kumer Sharma, Khadiza Begum, and Kinkon Rani Bhowmik. "Outcome of Hypertensive Disorders of Pregnancy." Community Based Medical Journal 3, no. 1 (2014): 46–52. http://dx.doi.org/10.3329/cbmj.v3i1.53329.

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Hypertension is the most common medical problem encountered in pregnancy and are leading causes of maternal, fetal and neonatal morbidity and mortality worldwide. Definitions, classifications, assessment and management of hypertensive disorders vary considerably in the literature and from country to country. In light of this, we aimed to evaluate different types of hypertensive disorders of pregnancy and to determine the impact of hypertensive disorders of pregnancy (HDP) on maternal, fetal and neonatal outcomes. This Cross Sectional descriptive study was conducted in the Department of Gynaeco

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Reddy, Shilpa Gopal, and Chinaiah Subramanyam Babu Rajendra Prasad. "Significance of platelet indices as severity marker in nonthrombocytopenic preeclampsia cases." Journal of Laboratory Physicians 11, no. 03 (2019): 186–91. http://dx.doi.org/10.4103/jlp.jlp_161_18.

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Abstract CONTEXT: Preeclampsia is often asymptomatic, and hence, its detection depends on signs or investigations. The platelet (PLT) parameters, in cases of preeclampsia with normal PLT count, are seldom analyzed. Hence, this study was undertaken to study the PLT parameters in nonthrombocytopenic preeclampsia cases. AIM: The aim was to evaluate the use of PLT indices as severity markers in nonthrombocytopenic preeclampsia cases. SUBJECTS AND METHODS: This prospective study was done on 120 cases of severe preeclampsia, 115 cases of preeclampsia without severe features, and 203 normal pregnant

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Grable, Ian. "Strip of the Month: Preeclampsia with Severe Features and Acute Abruption." NeoReviews 19, no. 2 (2018): e119-e126. http://dx.doi.org/10.1542/neo.19-2-e119.

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KHAN, SABIHA, and FAHAD ALROUMI. "PREECLAMPSIA WITH SEVERE FEATURES LEADING TO ARDS IN THE POSTPARTUM PERIOD." Chest 162, no. 4 (2022): A1010. http://dx.doi.org/10.1016/j.chest.2022.08.798.

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Amezquita, Fernando Aguirre, Lisa Gill, Juan Abrahante, et al. "Placental transcriptomic profile by RNA sequencing in Preeclampsia with Severe Features." American Journal of Obstetrics and Gynecology 226, no. 1 (2022): S287—S288. http://dx.doi.org/10.1016/j.ajog.2021.11.487.

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Rincon, Monica P., Kelly Kuo, Bethany Sabol, and Richard Burwick. "Pregnancy Outcomes in Gestational Hypertension and Preeclampsia Without Severe Features [32F]." Obstetrics & Gynecology 129 (May 2017): 69S. http://dx.doi.org/10.1097/01.aog.0000514861.89461.88.

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Beeraka, Sridivya S., Monica Rincon, and Richard M. Burwick. "Early Versus Late Onset Preeclampsia: Maternal Characteristics and Severe Features [38I]." Obstetrics & Gynecology 133, no. 1 (2019): 105S. http://dx.doi.org/10.1097/01.aog.0000558815.24870.22.

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Rana, Sarosh, Saira Salahuddin, Ariel Mueller, Anders H. Berg, Ravi I. Thadhani, and S. Ananth Karumanchi. "Angiogenic biomarkers in triage and risk for preeclampsia with severe features." Pregnancy Hypertension 13 (July 2018): 100–106. http://dx.doi.org/10.1016/j.preghy.2018.05.008.

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Hansen, John N., Jason Hine, and Tania D. Strout. "COVID-19 and preeclampsia with severe features at 34-weeks gestation." American Journal of Emergency Medicine 39 (January 2021): 252.e3–252.e5. http://dx.doi.org/10.1016/j.ajem.2020.06.052.

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Venkatappa, Shalini. "Never Let Failure Get Your Heart-A Case of Successfully Managed Peripartum Cardiomyopathy." Open Access Journal of Gynecology 8, no. 3 (2023): 1–3. http://dx.doi.org/10.23880/oajg-16000265.

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Peripartum Cardiomyopathy (PPCM) is a form of idiopathic heart failure that develops most commonly in the last month of gestation or during the first five months post-partum. Here we present a case of successfully managed peripartum cardiomyopathy in a patient with preeclampsia with severe features with pulmonary oedema and intrauterine death of foetus. The patient was managed conservatively until stable along the lines of pulmonary oedema and preeclampsia with severe features keeping various other differentials in mind followed by which the diagnosis of peripartum cardiomyopathy was suggested

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