Academic literature on the topic 'Prefrontal lobe function'

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Journal articles on the topic "Prefrontal lobe function"

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Guo, Huirong, Ning Zhao, Zheng Li, Binhua Zhu, He Cui, and Youhui Li. "Regional cerebral blood flow and cognitive function in patients with obsessive-compulsive disorder." Arquivos de Neuro-Psiquiatria 72, no. 1 (2014): 44–48. http://dx.doi.org/10.1590/0004-282x20130205.

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Objective: To explore the relationship between regional cerebral blood flow (CBF) and cognitive function in obsessive-compulsive disorder (OCD). Method: Single-photon emission computed tomography (SPECT) was performed for 139 OCD patients and 139 controls, and the radioactivity rate (RAR) was calculated. Cognitive function was assessed by the Wisconsin Card Sorting Test (WCST). Results: The RARs of the prefrontal, anterior temporal, and right occipital lobes were higher in patients than controls. For the WCST, correct and classification numbers were significantly lower, and errors and persiste
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Kang, Minji, ChoHye Youn, and Juyoung Lee. "Outdoor Garden Activities may Increase the Function of Prefrontal Cortex in Cognitively Impaired Older Adults." Journal of People, Plants, and Environment 28, no. 2 (2025): 173–91. https://doi.org/10.11628/ksppe.2025.28.2.173.

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Background and objective: With the rising prevalence of dementia in aging societies, there is an urgent need for effective, non-invasive interventions to support cognitive function and emotional stability. Gardening, a nature-based activity, has demonstrated potential to enhance mental and physical well-being, yet its direct impact on prefrontal cortex function remains largely unclear. This study investigates the effects of outdoor gardening activities (OGA) on prefrontal cortex (PFC) activation in elderly individuals with dementia and cognitive impairments, comparing these effects to those of
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Miller, Jacob A., Mark D'Esposito, and Kevin S. Weiner. "Using Tertiary Sulci to Map the “Cognitive Globe” of Prefrontal Cortex." Journal of Cognitive Neuroscience 33, no. 9 (2021): 1698–715. http://dx.doi.org/10.1162/jocn_a_01696.

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Abstract Stuss considered the human PFC as a “cognitive globe” [Stuss, D. T., & Benson, D. F. Neuropsychological studies of the frontal lobes. Psychological Bulletin, 95, 3–28, 1984] on which functions of the frontal lobe could be mapped. Here, we discuss classic and recent findings regarding the evolution, development, function, and cognitive role of shallow indentations or tertiary sulci in PFC, with the goal of using tertiary sulci to map the “cognitive globe” of PFC. First, we discuss lateral PFC (LPFC) tertiary sulci in classical anatomy and modern neuroimaging, as well as their devel
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Achim, Amélie M., and Martin Lepage. "Episodic memory-related activation in schizophrenia: meta-analysis." British Journal of Psychiatry 187, no. 6 (2005): 500–509. http://dx.doi.org/10.1192/bjp.187.6.500.

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BackgroundNumerous studies have examined the neural correlates of episodic memory deficits in schizophrenia, yielding both consistencies and discrepancies in the reported patterns of results.AimsTo identify in schizophrenia the brain regions in which activity is consistently abnormal across imaging studies of memory.MethodData from 18 studies meeting the inclusion criteria were combined using a recently developed quantitative meta-analytic approach.ResultsRegions of consistent differential activation between groups were observed in the left inferior prefrontal cortex, medial temporal cortex bi
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Preuss, Todd M. "Do Rats Have Prefrontal Cortex? The Rose-Woolsey-Akert Program Reconsidered." Journal of Cognitive Neuroscience 7, no. 1 (1995): 1–24. http://dx.doi.org/10.1162/jocn.1995.7.1.1.

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Primates are unique among mammals in possessing a region of dorsolateral prefrontal cortex with a well-developed internal granular layer. This region is commonly implicated in higher cognitive functions. Despite the histological distinctiveness of primate dorsolateral prefrontal cortex, the work of Rose, Woolsey, and Akert produced a broad consensus among neuroscientists that homologues of primate granular frontal cortex exist in nonprimates and can be recognized by their dense innervation from the mediodorsal thalamic nucleus (MD). Additional characteristics have come to be identified with do
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Selemon, Lynn D., Keith A. Young, Dianne A. Cruz, and Douglas E. Williamson. "Frontal Lobe Circuitry in Posttraumatic Stress Disorder." Chronic Stress 3 (January 2019): 247054701985016. http://dx.doi.org/10.1177/2470547019850166.

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Symptoms of posttraumatic stress disorder include hyperarousal, avoidance of trauma-related stimuli, re-experiencing of trauma, and mood changes. This review focuses on the frontal cortical areas that form crucial links in circuitry pertinent to posttraumatic stress disorder symptomatology: (1) the conditioned fear extinction circuit, (2) the salience circuit, and (3) the mood circuit. These frontal areas include the ventromedial prefrontal cortex (conditioned fear extinction), the dorsal anterior cingulate and insular cortices (salience), and the lateral orbitofrontal and subgenual cingulate
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Barceló, Francisco. "Does the Wisconsin Card Sorting Test Measure Prefontral Function?" Spanish Journal of Psychology 4, no. 1 (2001): 79–100. http://dx.doi.org/10.1017/s1138741600005680.

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This review describes a research program aimed at evaluating the validity and specificity of the Wisconsin Card Sorting Test (WCST), one of the most widely used tests of prefrontal function in clinical and experimental neuropsychology. In spite of its extensive use, voices of caution have arisen against the use of WCST scores as direct markers of prefrontal damage or dysfunction. Adopting a cognitive neuroscience approach, the present research program integrates behavioral, physiological, and anatomical information to investigate the cognitive and neural mechanisms behind WCST performance. The
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GREENWOOD, PAMELA M. "The frontal aging hypothesis evaluated." Journal of the International Neuropsychological Society 6, no. 6 (2000): 705–26. http://dx.doi.org/10.1017/s1355617700666092.

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That the human frontal lobes are particularly vulnerable to age-related deterioration has been frequently invoked as an explanation of functional decline in aging. This “frontal aging hypothesis” is evaluated in this review by examining evidence of selectively reduced frontal lobe function in aging. The frontal aging hypothesis predicts that functions largely dependent on frontal regions would decline in aging, while functions largely independent of frontal lobes would remain relatively spared. The hypothesis further predicts that age-related brain change would selectively impact frontal regio
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Colvin, Mary Kathryn, Kevin Dunbar, and Jordan Grafman. "The Effects of Frontal Lobe Lesions on Goal Achievement in the Water Jug Task." Journal of Cognitive Neuroscience 13, no. 8 (2001): 1129–47. http://dx.doi.org/10.1162/089892901753294419.

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Patients with prefrontal cortex lesions are impaired on a variety of planning and problem-solving tasks. We examined the problem-solving performance of 27 patients with focal frontal lobe damage on the Water Jug task. The Water Jug task has never been used to assess problem-solving ability in neurologically impaired patients nor in functional neuroimaging studies, despite sharing structural similarities with other tasks sensitive to prefrontal cortex function, including the Tower of Hanoi, Tower of London, and Wisconsin Card Sorting Task (WCST). Our results demonstrate that the Water Jug task
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Liu, Hanjing. "Critical Influence of Prefrontal Cortex-hippocampus Interactions on False Memories." Highlights in Science, Engineering and Technology 130 (February 24, 2025): 43–50. https://doi.org/10.54097/peafjq74.

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This thesis addresses the important role of prefrontal-hippocampal circuits in the generation of false memories. First analyses the influence of prefrontal and hippocampus in the generation of false memories by separately analysing the semantic processing in the prefrontal lobe and the effect of high cognitive load on memory. As well as the impact of the memory extraction process and memory integration on memory in hippocampal function. Finally, the integrated effects of prefrontal-hippocampal circuits on false memories are discussed as a whole. This section includes questions about the intera
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Dissertations / Theses on the topic "Prefrontal lobe function"

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Spanò, Goffredina. "Perceptual Mnemonic Medial Temporal Lobe Function in Individuals with Down Syndrome." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/255154.

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Behavioral data in individuals with Down syndrome (DS) and mouse models of the syndrome suggest impaired object processing. In this study we examined the component processes that may contribute to object memory deficits. A neuropsychological test battery was administered to individuals with DS (n=28), including tests targeting perirhinal cortex (PRC) and prefrontal cortex (PFC) function, tests of perception (i.e., convexity based figure ground perception), and tests of memory (object recognition and object-in-place learning). To compare to individuals with DS, the same number of typically deve
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Keifer, Ekaterina. "Performance of patients with ventromedial prefrontal, dorsolateral prefrontal, and non-frontal lesions on the Delis-Kaplan Executive Function System." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/830.

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Executive functioning is a multidimensional concept encompassing higher-order adaptive abilities, such as judgment, decision-making, self-monitoring, planning, and emotional regulation. Disruption in executive functioning often results in devastating impairments in vitally-important areas of life, such as one's ability to hold employment and maintain social relationships. Executive functions have been associated primarily with the prefrontal cortex. However, the nature and degree of the association between frontal lobe damage and performance on executive functioning tests remains controversial
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Gour, Natalina. "Réorganisation des systèmes anatomo-fonctionnels et de la topologie cérébrale entre les formes à début précoce et tardif de maladie d'Alzheimer. : Approche comportementale et en IRMf de repos." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM5069.

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Les fonctions cognitives reposent sur la communication dynamique de régions cérébrales interconnectées. Dans la maladie d’Alzheimer (MA), les travaux antérieurs suggèrent que le processus neuropathologique cible de façon précoce un ou plusieurs systèmes anatomo-fonctionnels spécifiques. La dysfonction du réseau par défaut a été objectivée de façon consistante. Cependant, ses relations avec les symptômes cliniques et avec l’atteinte des régions du lobe temporal interne qui lui sont fonctionnellement connectées restent à clarifier. L’IRM fonctionnelle de repos est une technique pertinente pour c
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Görgen, Kai. "On Rules and Methods: Neural Representations of Complex Rule Sets and Related Methodological Contributions." Doctoral thesis, Humboldt-Universität zu Berlin, 2019. http://dx.doi.org/10.18452/20711.

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Wo und wie werden komplexe Regelsätze im Gehirn repräsentiert? Drei empirische Studien dieser Doktorarbeit untersuchen dies experimentell. Eine weitere methodische Studie liefert Beiträge zur Weiterentwicklung der genutzten empirischen Methode. Die empirischen Studien nutzen multivariate Musteranalyse (MVPA) funktioneller Magnetresonanzdaten (fMRT) gesunder Probanden. Die Fragestellungen der methodischen Studie wurden durch die empirischen Arbeiten inspiriert. Wirkung und Anwendungsbreite der entwickelten Methode gehen jedoch über die Anwendung in den empirischen Studien dieser Arbeit hinaus.
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Lindner, Kyri-Kristin. "Zusammenhang zwischen posttraumatischen Riechstörungen und Läsionen des präfrontalen Kortex." 2019. https://tud.qucosa.de/id/qucosa%3A38027.

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Ziel: Das Ziel der vorliegenden Studie war einen Zusammenhang zwischen posttraumatischen Riechstörungen und Frontalhirnläsionen zu beweisen. Methode: Dafür wurden 51 Patienten mit posttraumatischen Riechstörungen und 50 Patienten mit Riechstörungen anderer Ätiologie untersucht. Der Grad der Riechstörungen wurde mit dem orthonasalen Testverfahren der Sniffin‘ Sticks sowie dem retronasalem Schmeckpulvertest eingestuft. Zusätzlich wurden neuropsychologische Tests (TMT-A, COWA, WCST, d2-R) durchgeführt, um Funktionen, die als typisch für die Frontallappen angesehen werden, zu überprüfen. Außerdem
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Books on the topic "Prefrontal lobe function"

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M, Uylings H. B., ed. The prefrontal cortex: Its structure, function, and pathology : proceedings of the 16th International Summer School of Brain Research, held at the Royal Tropical Institute and the Royal Netherlands Academy of Sciences Amsterdam, the Netherlands, from 28 August to 1 September 1989. Elsevier, 1990.

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M, Fuster Joaquin, Mikami Akichika, Sakata Hideo, and International Brain Research Organization. (4th : 1995 : Inuyama-shi, Japan), eds. The association cortex: Structure and function. Harwood Academic Publishers, 1997.

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Thierry, A.-M. Motor and Cognitive Functions of the Prefrontal Cortex. Springer-Verlag, 2011.

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Holder, Christen M., and Nicole Shay. Imaging the Networks of Executive Functions. Edited by Andrew C. Papanicolaou. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199764228.013.17.

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This chapter examines the different theoretical conceptualizations of executive functions and how neuroimaging can reveal their neuroanatomical mechanisms. After briefly considering various definitions and descriptions of executive function, it discusses the results of lesion studies that look into specific executive functions; namely, attention, working memory, inhibition, decision-making, planning and organization, processing speed, and cognitive flexibility or shifting. It also evaluates measures that are used to capture the executive functions just cited, along with the advances that have
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(Editor), H. Sakata, and J. M. Fuster (Editor), eds. Association Cortex: Structure and Function. Informa Healthcare, 1997.

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Book chapters on the topic "Prefrontal lobe function"

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Levy, Richard, and Patricia S. Goldman-Rakic. "Segregation of working memory functions within the dorsolateral prefrontal cortex." In Executive Control and the Frontal Lobe: Current Issues. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59794-7_4.

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Markowitsch, H. J., and J. Kessler. "Massive impairment in executive functions with partial preservation of other cognitive functions: the case of a young patient with severe degeneration of the prefrontal cortex." In Executive Control and the Frontal Lobe: Current Issues. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59794-7_11.

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Weinberger, Daniel R., Karen Faith Berman,, and David G. Daniel. "Prefrontal Cortex Dysfunction Schizophrenia." In Frontal Lobe Function and Dysfunction. Oxford University PressNew York, NY, 1991. http://dx.doi.org/10.1093/oso/9780195062847.003.0014.

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Abstract The notion that schizophrenia involves dysfunction of the frontal lobes dates back at least to Emil Kraepelin. In his view, the primary behavioral deficit in this disorder was a “destruction of the mainsprings of volition” secondary to anatomic pathology of the frontal cortex (Kraepelin, 1907). While consistent evidence of neuropathologic changes in the frontal lobe has not as yet emerged from research in schizophrenia, Kraepelin’s emphasis on symptoms suggestive of frontal dysfunction has been echoed throughout this century in phenomeno logic studies of this illness.
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Goldman-Rakic, Patricia S., and Harriet R. Friedman. "The Circuitry of Working Memory Revealed by Anatomy and Metabolic Imaging." In Frontal Lobe Function and Dysfunction. Oxford University PressNew York, NY, 1991. http://dx.doi.org/10.1093/oso/9780195062847.003.0004.

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Abstract Recent advances in anatomical, behavioral, and physiological techniques have produced new infornation about the nature of prefrontal function, its cellular basis, and its anatomical underpinnings. A major advance in our understanding of prefrontal function is the recognition that prefrontal subdivisions such as the principal sulcus (Walker’s area 46) are embedded in a complex but delimited network involving a large number of other cortical areas and subcortical structures (Fig. 4-1) (Goldman-Rakic, 1988; Selemon and Goldman-Rakic, 1988).
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Barbas, Helen, Jamie G. Bunce, and Maria Medalla. "Prefrontal Pathways that Control Attention." In Principles of Frontal Lobe Function. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199837755.003.0004.

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Mackey, Allyson P., Rajeev D. S. Raizada, and Silvia A. Bunge. "Environmental Influences on Prefrontal Development." In Principles of Frontal Lobe Function. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199837755.003.0013.

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Knight, Robert T. "Neural Oscillations and Prefrontal Cortex." In Principles of Frontal Lobe Function. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199837755.003.0054.

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Benton, Arthur L. "The Prefrontal Region: Its Early History." In Frontal Lobe Function and Dysfunction. Oxford University PressNew York, NY, 1991. http://dx.doi.org/10.1093/oso/9780195062847.003.0001.

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Abstract This historical sketch deals with the early development of knowledge and concepts about the structure and functions of the prefrontal region, i.e., the region anterior and mesial to those areas of frontal cortex having to do with motor functions (motor cortex and frontal eye fields) and speech (Broca’s area). The greater part of the prefrontal region has a characteristic cellular structure, frontal granular cortex, and within the region a number of areas are differentiated from each other on architectonic grounds.
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Fuster, Joaquín M. "Cognitive Functions of the Prefrontal Cortex." In Principles of Frontal Lobe Function. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199837755.003.0002.

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Sakai, Katsuyuki. "Network-Based Mechanism of Prefrontal Control." In Principles of Frontal Lobe Function. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199837755.003.0025.

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Conference papers on the topic "Prefrontal lobe function"

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Ungureanu, Florina, Tiberius Dumitriu, Vasile ion Manta, and Corina Cimpanu. "COGNITIVE LOAD AND SHORT TERM MEMORY EVALUATION BASED ON EEG TECHNIQUES." In eLSE 2017. Carol I National Defence University Publishing House, 2017. http://dx.doi.org/10.12753/2066-026x-17-116.

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The performance of learning process (standard system, e-learning or in a virtual environment) is associated with cognitive load and memory working activity. Working memory (or short-term memory) is the ability to hold multiple pieces of information in mind as you solve a problem. An example of short-term memory is a chess master who can explore several possible solutions mentally before choosing the one that will lead to checkmate. This ability to hold information temporarily to complete a task is specifically human. It causes frontal and pre-frontal lobe regions of the brain to become very ac
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Pontes, Maria Cibele Lima, Vinícius Romeu Beserra Diógenes, Natália Carolina Medeiros do Nascimento Rodrigues, et al. "Neural factors that define religiosity: neurophysiological distinction between the individual with religious and non-religious beliefs." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.694.

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Introduction: Religiosity and mystical experiences accompany society throughout history, integrating its identity formation. Neuroscience unveils neural correlations, maps the areas involved and activity patterns, and functional magnetic resonance imaging (fMRI) is applied to detect variations in activation of neural activity. Objectives: Thus, the objective is to understand the neurophysiological differences between individuals who experience religiosity and the mystical experiences of those without, through the fMRI. Methods: This literature review, collected data in April/2021 on Medline, P
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