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Academic literature on the topic 'Pregestational BMI'
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Journal articles on the topic "Pregestational BMI"
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Scherer-Adami, Fernanda, Michele Dutra-Rosolen, Francieli Schedler, Ioná Carreno, and Mabel N. Alves. "Nutritional status and dietary intake of pregnant women." Revista de Salud Pública 22, no. 1 (2020): 1–7. http://dx.doi.org/10.15446/rsap.v22n1.72795.
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Objective To evaluate weight gain during pregnancy according to the pregestational state in women who underwent prenatal care in Primary Health Care.Methods A cross-sectional study with the participation of 255 pregnant women. Socioeconomic and demographic variables were collected using a structured questionnaire. Women were evaluated for nutritional status and dietary intake. Data related to the age of the pregnant woman, gestational week, current weight, pregestational weight, and height were obtained from the prenatal follow-up form. The Statistical Package for the Social Sciences (SPSS) was used for statistical analysis.Results Pregestational nutritional status assessment showed that 43.2% (n=110) of the women started gestation with overweight and 4.3% (n=11) started with low weight. 51% percent (n=130) gained gestational weight above the recommended level. The mean age of women with pregestational BMI ≥ 25 kg/m² was significantly higher than that of those with BMI <25 kg/m² (p<0.001). Total energy (p=0.037) and calcium (p=0.004) intake were higher in women with weight gain above the recommended.Discussion The results presented highlight the importance of strategies in public health to avoid excess weight gain during pregnancy.Conclusion Pregnant women presented a gestational weight gain above the recommended maximum value according to pregestational BMI, which may contribute to adverse maternal and infant outcomes.
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Gómez-Vilarrubla, Ariadna, Berta Mas-Parés, Gemma Carreras-Badosa, et al. "DNA Methylation Signatures in Paired Placenta and Umbilical Cord Samples: Relationship with Maternal Pregestational Body Mass Index and Offspring Metabolic Outcomes." Biomedicines 12, no. 2 (2024): 301. http://dx.doi.org/10.3390/biomedicines12020301.
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An epigenomic approach was used to study the impact of maternal pregestational body mass index (BMI) on the placenta and umbilical cord methylomes and their potential effect on the offspring’s metabolic phenotype. DNA methylome was assessed in 24 paired placenta and umbilical cord samples. The differentially methylated CpGs associated with maternal pregestational BMI were identified and the metabolic pathways and the potentially related diseases affected by their annotated genes were determined. Two top differentially methylated CpGs were studied in 90 additional samples and the relationship with the offspring’s metabolic phenotype was determined. The results showed that maternal pregestational BMI is associated with the methylation of genes involved in endocrine and developmental pathways with potential effects on type 2 diabetes and obesity. The methylation and expression of HADHA and SLC2A8 genes in placenta and umbilical cord were related to several metabolic parameters in the offspring at 6 years (weight SDS, height SDS, BMI SDS, Δ BW-BMI SDS, FM SDS, waist, SBP, TG, HOMA-IR, perirenal fat; all p < 0.05). Our data suggest that epigenetic analysis in placenta and umbilical cord may be useful for identifying individual vulnerability to later metabolic diseases.
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Casanueva, Esther, María Eugenia Flores-Quijano, María Emila Roselló-Soberón, Luz María De-Regil, and Reyna Sámano. "Gestational Weight Gain as Predicted by Pregestational Body Mass Index and Gestational Age in Mexican Women." Food and Nutrition Bulletin 29, no. 4 (2008): 334–39. http://dx.doi.org/10.1177/156482650802900410.
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Objective To develop a reference pattern to evaluate gestational weight according to pregestational body mass index (BMI) and gestational age, using current longitudinal information from healthy pregnant women. Subjects and methods We followed 438 women with singleton pregnancies between weeks 16 and 36 of pregnancy. Women were excluded if they developed pathologic conditions during gestation, delivered malformed or dead fetuses, or delivered babies with a birthweight of less than 2500 or more than 4200 g or with a gestational age of less than 37 or more than 41 weeks. Weight, biochemical indicators, and clinical indicators were recorded every 4 weeks throughout the pregnancy. Data were analyzed by sequential regressions. Results Four equations for maternal predicted weight across categories of pregestational BMI (underweight, normal, overweight, and obese) and gestational ages were developed and synthesized in a table of reference values. Conclusions Optimal weight and weight gain during pregnancy can be estimated with our equations, which are corrected for pregestational BMI and gestational age.
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Lopez-Yañez Blanco, Arturo, Keyla M. Díaz-López, Jenny Vilchis-Gil, et al. "Diet and Maternal Obesity Are Associated with Increased Oxidative Stress in Newborns: A Cross-Sectional Study." Nutrients 14, no. 4 (2022): 746. http://dx.doi.org/10.3390/nu14040746.
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Overweight and obesity have become a world-health public problem, mainly for developing countries. Both health conditions have a higher prevalence among women of childbearing age. Physiopathology, overweight and obesity are characterized by a chronic oxidative stress status, which has deleterious effects on mothers and children. Hence, we determine whether the qualities of diet during pregnancy and maternal pregestational body mass index (BMI) are associated with increased oxidative stress markers in mothers and newborns. Two hundred forty-two (242) mother-newborn pairs were classified according to their pregestational BMI. Information on food intake was collected using a food frequency questionnaire in the third trimester of pregnancy. Levels of Malondialdehyde (MDA) and Nitric Oxide (NO) were measured in plasma from mothers at the end of the third trimester of pregnancy and from cord blood at birth. MDA and NO levels in mother–newborn pairs with maternal pregestational overweight or obesity were higher than in mother–newborn pairs with pregestational normal weight. For women (and newborns) who had a higher intake of fruit and vegetables, the levels of NO and MDA were lower. Lastly, women with pregestational obesity had lower fruit and vegetable intake during pregnancy and higher levels of oxidative stress and in their newborns.
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Chapper, Ana, Artur Munch, Camila Schermann, Carolina Carraro Piacentini, and Maria Thereza Martins Fasolo. "Obesity and periodontal disease in diabetic pregnant women." Brazilian Oral Research 19, no. 2 (2005): 83–87. http://dx.doi.org/10.1590/s1806-83242005000200002.
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This cross-sectional study investigated the impact of pregestational overweight and obesity on periodontal status of patients with gestational diabetes mellitus (GDM). Sixty pregnant women with gestational diabetes mellitus (GDM) were recruited for the study. According to the pregestational body mass index (BMI), patients were classified into 3 groups: normal, overweight or obese. The periodontal assessment parameters were the presence of gingival bleeding (GB) and bleeding on probing (BOP) per tooth. Clinical attachment loss (CAL) was assessed per tooth and classified according to following values: 1) absence of attachment loss; 2) between 1 and 2 mm, 3) between 3 and 5 mm; and 4) CAL > 6 mm. The means of individual percentage of teeth with GB and BOP and the means of the individual classified values of CAL were compared through ANOVA. Differences between the groups were established through post hoc Bonferroni test for multiple comparisons (p < 0.05). The analysis revealed significant differences between the normal group and the obese group considering GB (52.76% ± 27.99% and 78.85% ± 27.44%, respectively) and CAL (2.21 ± 0.41 and 2.61 ± 0.54, respectively). Although an increase was found in BOP as the BMI increased (ranging from 55.65% to 75.31%), no statistically significant differences were found among the groups. Patients with GDM and pregestational obesity had significantly more gingivitis and periodontal attachment loss that those with normal pregestational BMI. Periodontal treatment should be considered in the establishment of future recommendations for metabolic control for this special group of patients.
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Derikonjic, Minja, Marija Saric Matutinovic, Sandra Vladimirov Sopic, et al. "The Effects of Pregestational Overweight and Obesity on Maternal Lipidome in Pregnancy: Implications for Newborns’ Characteristics." International Journal of Molecular Sciences 25, no. 13 (2024): 7449. http://dx.doi.org/10.3390/ijms25137449.
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Obesity is an important risk factor for the development of pregnancy complications. We investigated the effects of pregestational overweight and obesity on maternal lipidome during pregnancy and on newborns’ characteristics. The study encompassed 131 pregnant women, 99 with pre-pregnancy body mass index (BMI) < 25 kg/m2 and 32 with BMI ≥ 25 kg/m2. Maternal lipid status parameters, plasma markers of cholesterol synthesis and absorption and sphingolipids were determined in each trimester. Data on neonatal height, weight and APGAR scores were assessed. The results showed a higher prevalence (p < 0.05) of pregnancy and childbirth complications among the participants with elevated pregestational BMI. Levels of total cholesterol, HDL-cholesterol (p < 0.05) and LDL-cholesterol (p < 0.01) were significantly lower, and concentrations of triglycerides were higher (p < 0.05) in women with increased pre-gestational BMI. Lower concentrations of the cholesterol synthesis marker, desmosterol, in the 2nd trimester (p < 0.01) and the cholesterol absorption marker, campesterol, in each trimester (p < 0.01, p < 0.05, p < 0.01, respectively) were also found in this group. Markers of maternal cholesterol synthesis were in positive correlation with neonatal APGAR scores in the group of mothers with healthy pre-pregnancy weight but in negative correlation in the overweight/obese group. Our results indicate that gestational adaptations of maternal lipidome depend on her pregestational nutritional status and that such changes may affect neonatal outcomes.
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Martins, Maria Eliana Pierre, Carmem Ulisses Peixoto Esmeraldo, João Paulo Duarte Sabiá, João Hallisson Lemos Carvalho, Fabíola Isabel Suano-Souza, and Roseli Oselka Saccardo Sarni. "Vitamin D Postpartum Concentrations: Relationship with Nutritional Condition and Morbidities during Pregnancy." Journal of Pregnancy 2018 (September 2, 2018): 1–6. http://dx.doi.org/10.1155/2018/1070528.
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Objective. To evaluate postpartum vitamin D deficiency/insufficiency and to relate it to pregestational BMI, gestational weight gain, and sociodemographic variables. Methods. This is a cross-sectional study with 225 full-term pregnant women. Data collected are as follows: maternal health, socioeconomic status, pregestational body mass index (BMI), and gestational weight gain. Laboratory evaluation included vitamin D [25(OH)D], calcium, phosphorus, magnesium, and alkaline phosphatase. Results. The mean age of women was 25.6±6.6 years. Dark skin color, low education, and work in the urban region were predominant. Regular sun exposure, photoprotection, and vitamin D supplementation were reported by 144 (64.0%), 44 (19.6%), and 5 (2.2%) women, respectively. The mean plasma concentrations of 25(OH)D were 26.0±6.8 ng/mL. Levels compatible with deficiency (<20 ng/mL) and insufficiency (20-30 ng/mL) were observed in 43 (19.1%) and 124 (55.1%) women, respectively. The increase of 1 ng/mL in 25(OH)D concentrations was associated with an increase of 0.16 mg/dL (95%CI 0.19 to 2.02; p=0.018) for calcium. There were no associations with 25(OH)D concentrations with pregestational BMI and with gestational weight gain. Conclusions. The high frequency of postpartum vitamin D deficiency/insufficiency in women with a full-term pregnancy in a region with a large and permanent sun exposure reminds us of the need for intervention policies aimed at preventing vitamin D deficiency during pregnancy.
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Ursache, Alexandra, Iuliana Elena Bujor, Alexandra Elena Cristofor, Denisa Oana Zelinschi, Dragos Nemescu, and Daniela Roxana Matasariu. "Maternal Body Mass Index Trends and Weight Gain in Singleton Pregnancies at the Time of Fetal Anatomic Survey: Changes in the Last Decade and New Trends in the Modern Era." Nutrients 15, no. 22 (2023): 4788. http://dx.doi.org/10.3390/nu15224788.
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(1) Background: the worldwide impact of overweight and obesity is rising, increasingly resembling an epidemic (a price we have to pay for our new way of living). (2) Methods: our study aims to evaluate the temporal trends and patterns of singleton pregnant women’s BMI (body mass index) in our region during a 12-year time frame between 2010 and 2021. (3) Results: We noticed a statistically significant difference between the BMIs of nulliparous and multiparous women and a significantly increased pregestational BMI in women with previous ART (assisted reproductive technology) procedures. Smoking pregnant women had a higher second trimester weight gain, regardless of parity. Women with folic acid supplementation alone had a higher BMI than those with folic acid and multivitamin intake. The weight of both nulliparous and multiparous women with chronic hypertension was statistically significantly higher in all three timeframes. Global weight gain did not reveal any statistically significant changes concerning women with pregestational diabetes, regardless of parity and the pregnancy trimester. (4) Conclusions: our article describes the trends in obesity and overweight in our middle-income country, in which this pathology is continuously growing, negatively influencing our reproductive-aged women and future generations.
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Lima, Raina Jansen Cutrim Propp, Rosângela Fernandes Lucena Batista, Cecília Claudia Costa Ribeiro, and Vanda Maria Ferreira Simões. "Effect of early determinants on adolescent fat-free mass." Revista de Saúde Pública 54 (December 15, 2020): 113. http://dx.doi.org/10.11606/s1518-8787.2020054002229.
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OBJECTIVE: To analyze the effects of early determinants on adolescent fat-free mass. METHODS: A c ohort s tudy w ith 5 79 a dolescents e valuated a t b irth a nd a dolescence i n a birth cohort in São Luís, Maranhão. In the proposed model, estimated by structural equation modeling, socioeconomic status (SES) at birth, maternal age, pregestational body mass index (BMI), gestational smoking, gestational weight gain, type of delivery, gestational age, sex of the newborn, length and weight at birth, adolescent socioeconomic status, “neither study/nor work” generation, adolescent physical activity level and alcohol consumption were tested as early determinants of adolescent fat-free mass (FFM). RESULTS: A higher pregestational BMI resulted in higher FFM in adolescence (Standardized Coefficient, SC = 0.152; p < 0.001). Being female implied a lower FFM in adolescence (SC = -0.633; p < 0.001). The negative effect of gender on FFM was direct (SC = -0.523; p < 0.001), but there was an indirect negative effect via physical activity level (SC = -0.085; p < 0.001). Women were less active (p < 0.001). An increase of 0.5 kg (1 Standard Deviation, SD) in birth weight led to a gain of 0.25 kg/m2 (0.106 SD) in adolescent FFM index (p = 0.034). Not studying or working had a negative effect on the adolescent’s FFM (SC = -0.106; p = 0.015). Elevation of 1 SD in the adolescent’s physical activity level represented an increase of 0.5 kg/m2 (0.207 SD) in FFM index (p < 0.001). CONCLUSIONS: The early determinants with the greatest effects on adolescent FFM are gender, adolescent physical activity level, pregestational BMI, birth weight and belonging to the “neither-nor” generation.
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Kim, Patrick, Tiffany Lowtan, David J. Rivera Vazquez, Kelsey Pozerski, Bradley H. Sipe, and Rachelle Schwartz. "Does an Early Isolated Decrease in Fetal Abdominal Circumference Heighten the Risk of Growth Restriction? [ID 1300]." Obstetrics & Gynecology 145, no. 6S (2025): 75S. https://doi.org/10.1097/aog.0000000000005918.060.
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INTRODUCTION: This study investigated if an isolated second-trimester fetal abdominal circumference (AC) less than 10th percentile (ACL10) is a risk factor for fetal growth restriction (FGR) and small for gestational age (SGA) neonates. METHODS: This multicenter retrospective cohort study analyzed patients who delivered term singletons between January 1, 2019, and January 1, 2024. The exposed group involved otherwise normally grown fetuses with isolated ACL10, measured between 18 and 24 weeks of gestation. Control participants were randomly selected from the same time period. Congenital anomalies were excluded. RESULTS: A total of 589 out of 1,213 patients met inclusion criteria (ACL10 n=213; control n=376). Mean AC was 6.3 percentile in ACL10 and 51.2 percentile in controls. Birth weight (2,782 g versus 3,257 g, P<.001) and percentiles (18.3% versus 41.8%, P<.001) were lower in ACL10. Abdominal circumference was an independent risk factor for FGR (adjusted odds ratio [aOR] 12.5 [6.7, 23.4]) and SGA (aOR 5.08 [3.32, 7.76]). Although more pregestational diabetic mothers were ACL10 (10.3% versus 3.7%, P=.001), pregestational diabetes was protective of FGR (aOR 0.15 [0.04, 0.54]). As maternal body mass index (BMI) increased, likelihood of FGR (aOR 0.95 [0.90, 0.995]) and SGA (aOR 0.94 [0.91, 0.97]) decreased. Black patients were more likely to have ACL10 (36.2% versus 25.8%, P=.027). There were no differences in parity, gestational diabetes, chronic/gestational hypertension, preeclampsia, BMI, or mode of delivery between cohorts. CONCLUSIONS/IMPLICATIONS: Isolated second-trimester ACL10 in an otherwise normally grown fetus is an independent risk factor for both FGR and SGA. Increased maternal BMI was protective of FGR and SGA. Pregestational diabetes was protective of FGR but not SGA.