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1

Khalil, Asma, and Pat O'Brien. "Challenges of twin pregnancy." British Journal of Midwifery 15, no. 5 (2007): 266–72. http://dx.doi.org/10.12968/bjom.2007.15.5.23398.

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2

Freyer, Anette M. "Drug-prescribing challenges during pregnancy." Obstetrics, Gynaecology & Reproductive Medicine 18, no. 7 (2008): 180–86. http://dx.doi.org/10.1016/j.ogrm.2008.05.005.

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3

Pradhan, Saplin. "Oral Health Challenges During Pregnancy." Indian Journal of Public Health Research & Development 10, no. 11 (2019): 1060. http://dx.doi.org/10.5958/0976-5506.2019.03646.5.

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4

Cadoo, K. A., D. M. Graham, and D. N. Carney. "Therapeutic challenges: Cancer and pregnancy." Journal of Clinical Oncology 28, no. 15_suppl (2010): e19668-e19668. http://dx.doi.org/10.1200/jco.2010.28.15_suppl.e19668.

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5

Frances, Gill. "Teenage pregnancy: successes and challenges." Practice Nursing 22, no. 1 (2011): 12–16. http://dx.doi.org/10.12968/pnur.2011.22.1.12.

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6

Weiner, Carl P., Catalin Buhimschi, and Peter Swaan. "Drug-prescribing challenges during pregnancy." Current Obstetrics & Gynaecology 15, no. 3 (2005): 157–65. http://dx.doi.org/10.1016/j.curobgyn.2005.03.005.

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7

Merims, Sharon, Stephen Frank, Tamar Yablonski-Peretz, and Michal Lotem. "Melanoma in Pregnancy: Therapeutic Challenges." Current Dermatology Reports 3, no. 3 (2014): 149–52. http://dx.doi.org/10.1007/s13671-014-0082-1.

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8

Mihălţan, Florin Dumitru, Sabina Antonela Antoniu, and Ruxandra Ulmeanu. "Asthma and pregnancy: therapeutic challenges." Archives of Gynecology and Obstetrics 290, no. 4 (2014): 621–27. http://dx.doi.org/10.1007/s00404-014-3342-1.

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9

Naqvi, Tasneem Z. "Challenges in cardiology research in pregnancy." Future Cardiology 10, no. 6 (2014): 759–68. http://dx.doi.org/10.2217/fca.14.45.

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10

Berwal, Vidhika, Amit Kyal, Dorothy Dessa, Joyita Bhowmik, Payel Mondal, and Partha Mukhopadhyay. "Pregnancy with thalassemia: challenges and outcomes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 4 (2018): 1613. http://dx.doi.org/10.18203/2320-1770.ijrcog20181365.

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Background: Thalassemia syndromes are autosomal recessive disorders and the most commonly inherited haemoglobinopathies in the world. HbE β is the most common type of thalassemia in eastern India. The objectives of the study include maternal outcome and complications like anemia, hypertensive disorders, gestational diabetes mellitus and also to study the neonatal outcome in terms of low birth weight, prematurity and other complications.Methods: A prospective longitudinal study carried out over a period of one year from July 2016 to June 2017 in Medical College, Kolkata. Fifty antenatal thalass
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11

Rueda-Clausen, Christian F., Jeffrey Campbell, and Philip N. Baker. "Current challenges in pregnancy-related mortality." Obstetrics, Gynaecology & Reproductive Medicine 21, no. 8 (2011): 229–35. http://dx.doi.org/10.1016/j.ogrm.2011.05.003.

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12

Schieber, Alexandra, and David O’Gurek. "Vaccinating in Pregnancy: Opportunities and Challenges." Primary Care: Clinics in Office Practice 47, no. 3 (2020): 443–52. http://dx.doi.org/10.1016/j.pop.2020.05.001.

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13

S. Jabor, Soad, Huda Salim Al-Habeeb, and Nibras S. Khadum. "PSORIASIS AND PREGNANCY CHALLENGES AND RISKS." International Journal of Advanced Research 8, no. 02 (2020): 242–48. http://dx.doi.org/10.21474/ijar01/10459.

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14

Levine, Deborah Jo, Evelyn Horn, Irene Lang, Ron Oudiz, and Dianne Zwicke. "The Challenges of PAH in Pregnancy." Advances in Pulmonary Hypertension 10, no. 3 (2011): 181–89. http://dx.doi.org/10.21693/1933-088x-10.3.181.

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PAH patients who become pregnant– certainly against medical advice– or whose disease is diagnosed while pregnant present myriad challenges. On October 17, 2011, a group of physicians who have dealt with these complicated issues met by telephone to discuss their approaches and thoughts on dealing with these unique patients. Co-guest editor Deborah Jo Levine facilitated the discussion among Drs Ron Oudiz, Director of the Pulmonary Hypertension Center at Los Angeles County Harbor-UCLA Medical Center; Irene Lang, cardiologist at the Medical University of Vienna; Evelyn Horn, Director of the Heart
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15

Sagay, A. "I317 CHALLENGES OF HIV AND PREGNANCY." International Journal of Gynecology & Obstetrics 119 (October 2012): S240—S241. http://dx.doi.org/10.1016/s0020-7292(12)60347-6.

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16

Durga, Padmaja, Shibani Padhy, and Anupama Bardaa. "Challenges of Cardiopulmonary Resuscitation during Pregnancy." Indian Journal of Cardiovascular Disease in Women WINCARS 04, no. 01 (2019): 032–39. http://dx.doi.org/10.1055/s-0039-1692304.

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AbstractCardiac arrest, though rare, is the most feared complication in the pregnant woman as it involves two lives. Most arrests occur because of conditions that result from the pregnancy itself or from preexisting medical conditions exacerbated by the pregnancy. Prompt resuscitative efforts are crucial for favorable outcomes for the mother and fetus. The basic principles of resuscitation during pregnancy such as airway, breathing, and circulation are similar to the resuscitation in a cardiopulmonary arrest in any patient; however, certain modifications are necessary to account for the physio
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17

Oyston, Charlotte, Christian F. Rueda-Clausen, and Philip N. Baker. "Current challenges in pregnancy-related mortality." Obstetrics, Gynaecology & Reproductive Medicine 24, no. 6 (2014): 162–69. http://dx.doi.org/10.1016/j.ogrm.2014.04.007.

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18

Oyston, Charlotte, Christian F. Rueda-Clausen, and Philip N. Baker. "Current challenges in pregnancy-related mortality." Obstetrics, Gynaecology & Reproductive Medicine 27, no. 7 (2017): 199–205. http://dx.doi.org/10.1016/j.ogrm.2017.04.005.

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19

Oyston, Charlotte, and Philip N. Baker. "Current challenges in pregnancy-related mortality." Obstetrics, Gynaecology & Reproductive Medicine 30, no. 2 (2020): 55–61. http://dx.doi.org/10.1016/j.ogrm.2019.11.003.

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20

St-André, Martin. "Psychotherapy during Pregnancy: Opportunities and Challenges." American Journal of Psychotherapy 47, no. 4 (1993): 572–90. http://dx.doi.org/10.1176/appi.psychotherapy.1993.47.4.572.

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21

Pinotti, JoséAristodemo, and Anibal Faúndes. "Unwanted pregnancy: challenges for health policy." International Journal of Gynecology & Obstetrics 30, Supplement (1989): 97–102. http://dx.doi.org/10.1016/0020-7292(89)90108-2.

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22

Murphy, H. R., R. Bell, A. Dornhorst, R. Forde, and N. Lewis-Barned. "Pregnancy in Diabetes: challenges and opportunities for improving pregnancy outcomes." Diabetic Medicine 35, no. 3 (2018): 292–99. http://dx.doi.org/10.1111/dme.13579.

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23

Ouassour, Salma, Abdelhai Adib Filali, Mohamed Raiss, et al. "Retroperitoneal Ectopic Pregnancy: Diagnosis and Therapeutic Challenges." Case Reports in Surgery 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/9871865.

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Background. Retroperitoneal ectopic pregnancy is extremely rare. This unusual location represents a great challenge for clinicians due to the difficulties of diagnosis and high risk of life-threatening complications. Case Report. We report the case of a spontaneous early pregnancy of undetermined location in a patient with a history of previous laparoscopic surgery. Diagnosis steps using clinical examination, ultrasound, and magnetic resonance imaging led to the localization of the pregnancy, in the left side of the para-aortic region, in the retroperitoneal space. Conclusion. Retroperitoneal
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24

Lacković, Milan, Dejan Filimonović, and Dejan Nikolić. "Challenges and complications of maternal obesity in pregnancy." Medicinski podmladak 71, no. 4 (2020): 54–58. http://dx.doi.org/10.5937/mp71-27850.

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The prevalence of obesity and obesity-related health problems is increasing worldwide, especially among woman and man of reproductive age where obesity is designated as one of the most important global health threats in 21st century. Pregnancy in obese woman is considered as a high-risk pregnancy. Pre-pregnancy obesity and excessive gestational weight gain (GWG) are distinct risk factors with differing associated adverse outcomes, and they could also carry a cumulative negative impact on pregnancy course. Pre-pregnancy obesity is the anthropometric parameter most strongly correlated with perin
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25

Amarjothi , J. M. V., Villalan Ramasamy, G. R. Senthil Kumaran, and O. L. Naganath Babu. "Challenges Associated with Colorectal Cancer in Pregnancy." Case Reports in Gastroenterology 13, no. 2 (2019): 253–57. http://dx.doi.org/10.1159/000500078.

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Colorectal cancer is epidemiologically a disease of the middle-aged and elderly. However, it may occur in the young where it presents with virulent biological behavior and poor prognosis. The symptoms of colorectal cancer may be masked by symptoms of pregnancy and the patient may attribute it to the pregnancy, especially in multiparous patients whose anxiety and apprehension levels may be lower and hence present late to health care providers. Antenatal women who present with such symptoms must be investigated further under the available repertoire of investigations possible in pregnancy withou
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26

Sakthivel, A., A. J. Nankervis, J. Conn, J. Oats, and S. Chitturi. "318. POLYURIA IN PREGNANCY - CHALLENGES OF DIAGNOSIS!" Reproduction, Fertility and Development 22, no. 9 (2010): 118. http://dx.doi.org/10.1071/srb10abs318.

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Increased urinary frequency is a widely experienced symptom in pregnancy; true polyuria is less common and can have a number of causes. It is essential, however that it should be recognized and appropriately investigated, as it may be potentially life threatening to mother and fetus. Diabetes insipidus (DI) is a rare complication of pregnancy. It can be the first presentation of pre-gestational DI, gestational DI or DI associated with acute fatty liver of pregnancy. The latter conditions are illustrated by the following two clinical cases. Osmotic homeostasis can be altered in pregnancy due to
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27

Seshiah, V., N. Bhavatharini, Sanjeev V. K., Changanidi A. R. A., and R. Aruyerchelvan. "Problems and solutions for the diagnosis of gestational diabetes mellitus in non metropolitan areas in India." International Journal Of Community Medicine And Public Health 7, no. 4 (2020): 1607. http://dx.doi.org/10.18203/2394-6040.ijcmph20201482.

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Management of gestational diabetes mellitus and hyperglycemia in pregnancy is challenging in developing country like India. There are several logistic, socioeconomic and cultural issues faced by the care providers and the patients alike. In order to tackle these challenges, Diabetes in Pregnancy Study Group of India (DIPSI) recommendations consisting of a single glucose challenge test is ideal to evaluate the glucose intolerance and early initiation of doctors’ prescription. This review article explores the practical challenges associated with managing gestational diabetes mellitus and recomme
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28

&NA;. "Treatment of depression in pregnancy poses challenges." Reactions Weekly &NA;, no. 1112 (2006): 3. http://dx.doi.org/10.2165/00128415-200611120-00006.

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29

Chaudhary, Bhupendra, Rashmi Basvantsing Rajput, and Ansh Chaudhary. "Multiple sclerosis in pregnancy: meeting the challenges." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 6 (2020): 2659. http://dx.doi.org/10.18203/2320-1770.ijrcog20202067.

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Multiple sclerosis being a chronic, autoimmune inflammatory disease of central nervous system with its common and uncommon semiology has a predilection for women of child bearing age. The stressful period of pregnancy is further complicated with presence of multiple sclerosis. Overall multiple sclerosis has stabilising effect on pregnancy especially in its second and third trimester but adversely affects the post-partum period with increasing relapse rate. This is related with intense immune response triggered by marked changes in levels of circulating hormones. A better understanding of anti-
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30

Igwemadu, GeraldTochukwu, Olubunmi Tunde-Olatunji, UcheAugustine Akunaeziri, and EnangEno Enang. "Advanced abdominal pregnancy: The challenges of management." Nigerian Journal of Medicine 29, no. 3 (2020): 514. http://dx.doi.org/10.4103/njm.njm_34_20.

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31

McKinley, Michelle C., Virginia Allen-Walker, Caroline McGirr, Ciara Rooney, and Jayne V. Woodside. "Weight loss after pregnancy: challenges and opportunities." Nutrition Research Reviews 31, no. 2 (2018): 225–38. http://dx.doi.org/10.1017/s0954422418000070.

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AbstractIt is important to pay attention to weight management before and between pregnancies, as women have an increased risk of weight gain during the reproductive years. Having a baby is a life-changing event for women and the challenge of weight management amidst this period of major physiological, psychological and social change should not be underestimated. However, the postpartum period offers an opportune time for lifestyle interventions, as women may have heightened awareness of their own and their wider families’ health. Systematic reviews indicate that interventions including both di
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32

Sunita, V., M. Ramya, T. Shruthi, and G. Sangeetha. "Heterotopic Pregnancy: Challenges in Diagnosis and Management." Open Journal of Obstetrics and Gynecology 06, no. 08 (2016): 445–50. http://dx.doi.org/10.4236/ojog.2016.68059.

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33

Isaacs, John D., Everett F. Magann, Rick W. Martin, Suneet P. Chauhan, and John C. Morrison. "Obstetric Challenges of Massive Obesity Complicating Pregnancy." Obstetrical & Gynecological Survey 49, no. 8 (1994): 517–18. http://dx.doi.org/10.1097/00006254-199408000-00001.

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34

Crnogorac, Snezana, and Vesna Miranovic. "Pregnancy after malignant disease – challenges and possibilities." Journal of Perinatal Medicine 46, no. 4 (2018): 349–53. http://dx.doi.org/10.1515/jpm-2017-0165.

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35

Ahuja, Vanita, Satinder Gombar, Navneet Kumar, Nitika Goyal, and Kanika Gupta. "Pregnancy with bilateral tubercular pleural effusion: challenges." Tropical Doctor 44, no. 2 (2014): 116–18. http://dx.doi.org/10.1177/0049475513517117.

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36

Spencer, Thomas E. "Early pregnancy: Concepts, challenges, and potential solutions." Animal Frontiers 3, no. 4 (2013): 48–55. http://dx.doi.org/10.2527/af.2013-0033.

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37

Sazonova, E. O., and S. S. Ramazanova. "Challenges in the diagnosis of ectopic pregnancy." Endoskopicheskaya khirurgiya 20, no. 6 (2014): 38. http://dx.doi.org/10.17116/endoskop2014638-41.

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38

Chaudron, Linda H. "Complex Challenges in Treating Depression During Pregnancy." American Journal of Psychiatry 170, no. 1 (2013): 12–20. http://dx.doi.org/10.1176/appi.ajp.2012.12040440.

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39

Taraborelli, Mara, and Doruk Erkan. "Pregnancy-Related Challenges in Systemic Autoimmune Diseases." Journal of Infusion Nursing 38, no. 5 (2015): 360–68. http://dx.doi.org/10.1097/nan.0000000000000124.

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40

Awwad, Johnny, Nadine Hammoud, Chantal Farra, Farah Fares, George Abi Saad, and Ghina Ghazeeri. "Abdominal Wall Desmoid during Pregnancy: Diagnostic Challenges." Case Reports in Obstetrics and Gynecology 2013 (2013): 1–3. http://dx.doi.org/10.1155/2013/350894.

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Background. Desmoids are benign tumors, with local invasive features and no metastatic potential, which have rarely been described to be pregnancy associated.Case. We described the rapid growth of an anterior abdominal wall mass in a 40-year-old pregnant woman. Due to its close proximity to the enlarged uterus, it was misdiagnosed to be a uterine leiomyoma by ultrasound examination. Final tissue diagnosis and radical resection were done at the time of abdominal delivery.Conclusion. Due to the diagnostic limitations of imaging techniques, desmoids should always be considered when the following
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41

Mahajan, Niraj N. "Advanced extrauterine pregnancy: diagnostic and therapeutic challenges." American Journal of Obstetrics and Gynecology 199, no. 6 (2008): e11. http://dx.doi.org/10.1016/j.ajog.2008.06.024.

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42

Sanu, Olaleye, Maryam Parisaei, Edgar Dorman, Olayinka Akinfenwa, and Katrina Erskine. "Advanced cervical pregnancy: Diagnostic and management challenges." European Journal of Obstetrics & Gynecology and Reproductive Biology 134, no. 1 (2007): 129–30. http://dx.doi.org/10.1016/j.ejogrb.2006.07.021.

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43

Worley, Kevin C., Michael D. Hnat, and F. Gary Cunningham. "Advanced extrauterine pregnancy: diagnostic and therapeutic challenges." American Journal of Obstetrics and Gynecology 198, no. 3 (2008): 297.e1–297.e7. http://dx.doi.org/10.1016/j.ajog.2007.09.044.

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44

Lenhard, Miriam S., Ingo Bauerfeind, and Michael Untch. "Breast cancer and pregnancy: Challenges of chemotherapy." Critical Reviews in Oncology/Hematology 67, no. 3 (2008): 196–203. http://dx.doi.org/10.1016/j.critrevonc.2008.02.007.

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45

Pereg, David, Gideon Koren, and Michael Lishner. "Cancer in pregnancy: Gaps, challenges and solutions." Cancer Treatment Reviews 34, no. 4 (2008): 302–12. http://dx.doi.org/10.1016/j.ctrv.2008.01.002.

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46

Degli Esposti, Silvia, and Dhvani Shah. "Hepatitis B in Pregnancy: Challenges and Treatment." Gastroenterology Clinics of North America 40, no. 2 (2011): 355–72. http://dx.doi.org/10.1016/j.gtc.2011.03.005.

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47

Hartman, Rebecca I., and Alexa B. Kimball. "Performing research in pregnancy: Challenges and perspectives." Clinics in Dermatology 34, no. 3 (2016): 410–15. http://dx.doi.org/10.1016/j.clindermatol.2016.02.014.

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48

La Marca-Ghaemmaghami, Pearl, and Ulrike Ehlert. "Stress During Pregnancy." European Psychologist 20, no. 2 (2015): 102–19. http://dx.doi.org/10.1027/1016-9040/a000195.

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High levels of stress during pregnancy are associated with a number of adverse psychological and physiological outcomes for mother and child. These effects seem to be transmitted in part by one of the major stress-responsive systems, namely the hypothalamic-pituitary-adrenal (HPA) axis, which includes the hormone cortisol. However, as inconsistent study results indicate, methodology poses a substantial challenge to the investigation of stress during pregnancy. For example, although measures of maternal psychological stress and stress hormones are independently related to adverse pregnancy outc
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49

Zwicke, Dianne L. "PAH and Pregnancy: Physiologic Changes, Challenges, and Outcomes." Advances in Pulmonary Hypertension 10, no. 3 (2011): 173–77. http://dx.doi.org/10.21693/1933-088x-10.3.173.

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For most expectant mothers, pregnancy is a happy time. It is a time of scheduled obstetrical appointments, prenatal vitamins, prenatal classes, and baby showers, with the greatest concern being shopping for the anticipated family addition. No one “expects” complications or a new diagnosis during their pregnancy. When complications do occur, the majority are related to the development of the fetus, not the health of the mother. Unfortunately, idiopathic pulmonary arterial hypertension (IPAH) is an unforgiving and devastating disease, and as many as 80% of new diagnoses are made during the child
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50

Soo-Hoo, Sarah, Jenny Seong, Brandon R. Porten, and Nedaa Skeik. "Challenges of Takayasu Arteritis in Pregnancy: A Case Report." Vascular and Endovascular Surgery 51, no. 4 (2017): 195–98. http://dx.doi.org/10.1177/1538574417698904.

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Takayasu arteritis is a rare, chronic vasculitis of unknown etiology characterized by inflammation of the aorta and its main branches. Although Takayasu arteritis mostly affects women of childbearing age, there is a paucity in the literature on pregnancy associated with Takayasu arteritis. Pregnant patients are at increased risk of cardiovascular complications, including hypertension and congestive heart failure, which may jeopardize both maternal and fetal outcomes. Furthermore, optimal management has not yet been established for pregnant patients with Takayasu arteritis, posing a clinical ch
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