Academic literature on the topic 'Pregnancy in animals – Research'

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Journal articles on the topic "Pregnancy in animals – Research"

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Balhara, Ashok K., Meenakshi Gupta, Surender Singh, Ashok K. Mohanty, and Inderjeet Singh. "Early Pregnancy Diagnosis in Bovines: Current Status and Future Directions." Scientific World Journal 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/958540.

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An early and accurate diagnosis of reproductive dysfunctions or aberrations is crucial to better reproductive management in livestock. High reproductive efficiency is a prerequisite for high life-time production in dairy animals. Early pregnancy diagnosis is key to shorten the calving interval through early identification of open animals and their timely treatment and rebreeding so as to maintain a postpartum barren interval close to 60 days. A buffalo, the most important dairy animal in the Indian subcontinent, is known for problems related to high calving interval, late puberty, and high incidence of anestrus. Lack of reliable cow-side early pregnancy diagnosis methods further aggravates the situation. Several methods of pregnancy diagnosis are being practiced in bovine species, yet none qualifies as the ideal pregnancy diagnosis method due to the inherent limitations of sensitivity, accuracy, specificity, speed, and ease of performing the test. The advancement of molecular techniques like proteomics and their applications in animal research has given a new hope to look for pregnancy biomarker molecules in these animals. This review attempts to examine common pregnancy diagnosis methods available for dairy animals, while assessing the usefulness of the modern technologies in detecting novel pregnancy markers and designing future strategies for research in this area.
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Poulsen, Keith P., and Charles J. Czuprynski. "Pathogenesis of listeriosis during pregnancy." Animal Health Research Reviews 14, no. 1 (2013): 30–39. http://dx.doi.org/10.1017/s1466252312000242.

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AbstractListeria monocytogenescauses several clinical manifestations in humans and domestic animals. This bacterium is a saprophyte in soil and ensiled feeds, which are sources of infection for food producing animals (i.e. ruminants). The most common route of infection for people is via ingestion of contaminated ready-to-eat food products such as produce, soft cheeses and deli meats. In the United States,L. monocytogenescauses relatively few cases of clinical disease compared to other food-borne pathogens. However, clinical listeriosis is associated with high mortality, especially in immunocompromised patients, pregnant women, neonates, and the elderly.Listeriais an intracellular pathogen, which has been widely used in basic research to elucidate mechanisms of molecular pathogenesis and protective cell-mediated immunity. Despite the sizeable knowledge onL. monocytogenespathogenesis, key points regarding listeriosis during pregnancy and the perinatal period remain unknown. This review summarizes listeriosis in humans and domestic animals during pregnancy, and animal models used to study the pathogenesis and immune response toL. monocytogenesinfection during these periods.
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Hryhorowicz, Magdalena, Daniel Lipiński, Szymon Hryhorowicz, Agnieszka Nowak-Terpiłowska, Natalia Ryczek, and Joanna Zeyland. "Application of Genetically Engineered Pigs in Biomedical Research." Genes 11, no. 6 (2020): 670. http://dx.doi.org/10.3390/genes11060670.

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Progress in genetic engineering over the past few decades has made it possible to develop methods that have led to the production of transgenic animals. The development of transgenesis has created new directions in research and possibilities for its practical application. Generating transgenic animal species is not only aimed towards accelerating traditional breeding programs and improving animal health and the quality of animal products for consumption but can also be used in biomedicine. Animal studies are conducted to develop models used in gene function and regulation research and the genetic determinants of certain human diseases. Another direction of research, described in this review, focuses on the use of transgenic animals as a source of high-quality biopharmaceuticals, such as recombinant proteins. The further aspect discussed is the use of genetically modified animals as a source of cells, tissues, and organs for transplantation into human recipients, i.e., xenotransplantation. Numerous studies have shown that the pig (Sus scrofa domestica) is the most suitable species both as a research model for human diseases and as an optimal organ donor for xenotransplantation. Short pregnancy, short generation interval, and high litter size make the production of transgenic pigs less time-consuming in comparison with other livestock species This review describes genetically modified pigs used for biomedical research and the future challenges and perspectives for the use of the swine animal models.
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Michell, A. R. "Sodium and research in farm animals: problems of requirement, deficit, and excess." Outlook on Agriculture 14, no. 4 (1985): 179–82. http://dx.doi.org/10.1177/003072708501400404.

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There is no doubt of the biological importance of salt in the physiological processes of all animals. Nevertheless, there is great uncertainty about the level of salt intake necessary to maintain the health of farm animals in varying circumstances such as pregnancy and lactation. It appears that published recommendations are far too high, which is not only misleading from the veterinary point of view but is reflected in exaggerated estimates of human requirements.
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Subramani, Ramadevi, Adriana Estrada, Madeline Dixon, et al. "Pregnancy Inhibits Mammary Carcinogenesis by Persistently Altering the Hypothalamic–Pituitary Axis." Cancers 13, no. 13 (2021): 3207. http://dx.doi.org/10.3390/cancers13133207.

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Early full-term pregnancy is known to reduce the lifetime risk of breast cancer. Although the phenomenon of parity-induced protection is well-established, the physiological mechanisms involved in this protection are not clear. Earlier reports have shown that pregnancy results in alterations of hormone levels. How pregnancy affects hypothalamic hormones and how the change, if any, influences breast cancer is not well understood. Seven-week-old female Lewis rats were given N-methyl-N-nitrosourea. Two weeks post carcinogen exposure, a set of females were housed with males to generate the parous rats and another set of rats served as the nulliparous controls. Mammary tumorigenesis was assessed for 9 months. Hypothalamic and pituitary levels of hormones were measured at various timepoints. Further, animals were also challenged with growth hormone and prolactin secretagogues to test the effect of pregnancy on the hypothalamic–pituitary hormonal axis. Persistent alterations in the level of growth hormone-releasing hormone, thyrotropin releasing hormone, dopamine, and somatostatin in the hypothalamus of parous animals was observed. Further, we also observed that pregnancy had a significant effect on the pituitary gland and its response to growth hormone and prolactin secretagogues. Our studies using the rodent model system demonstrate that pregnancy could be reducing the risk of breast cancer by persistently altering the hypothalamic–pituitary axis, which could have implications for breast cancers in humans as well.
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Desaulniers, Daniel M., Alan K. Goff, Keith J. Betteridge, Janice E. Rowell, and Peter F. Flood. "Reproductive hormone concentrations in faeces during the oestrous cycle and pregnancy in cattle (Bos taurus) and muskoxen (Ovibos moschatus)." Canadian Journal of Zoology 67, no. 5 (1989): 1148–54. http://dx.doi.org/10.1139/z89-165.

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Difficulties associated with blood sampling of wild animals are a deterrent to reproductive research but might be circumvented by the development of noninvasive techniques. Samples of faeces were collected from 4 cyclic and 19 pregnant domestic cows and from 6 female muskoxen during anoestrus, the oestrous cycle, and pregnancy. In cows, the faecal progesterone profile corresponded well with plasma values in cyclic and pregnant animals. Increased concentrations of 15-keto-13,14-dihydroprostaglandin F2α could be detected in bovine faeces during luteolysis using data from a group of animals. A large increase in total oestrogen occurred in both faeces and plasma after the 12th week of pregnancy, confirming that faecal oestrogen levels can be used for pregnancy diagnosis. In the muskox, faecal concentations of total oestrogen and progesterone were correlated with reproductive status, and animals that were anoestrous, oestrous, pregnant, or in the luteal phase of the cycle could be recognized.
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Lestari, Tita Damayanti. "Study of the Anti – Pregnancy - Associated Glycoprotein (Anti – Pag) Resulted from Antigen Pag Immunization, as Prospective Early Pregnancy Detector in Animals." Cercetari Agronomice in Moldova 49, no. 3 (2016): 111–18. http://dx.doi.org/10.1515/cerce-2016-0030.

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Abstract Blastocyst protein named pregnancy-associated glycoprotein (PAG) has been isolated from pregnant dairy cow serum. PAG yielded from previous research issued from pregnant animals, wherein was specifically produced. This study is an initial research to use PAG as an antigen to be injected to rabbit in order to produce the corresponding antibody. The objective of the research was to study the character of anti-pregnancy-associated glycoprotein (Anti-PAG), as a result of immunization of PAG and to learn its specification reaction. The PAG isolate had bovine origin (molecular weight-MW of 67.34 kDa) and issued from previous research. Injection of PAG isolate could stimulate the production of Anti-PAG as an immunization response. Immunization was done by double booster inoculation. Anti-PAG derived from immunization was characterized via antibody titer value using ELISA technique. Specificity test of Anti-PAG was carried on by Western Blot technique. Results revealed that injection of PAG isolate to the rabbit stimulates anti-PAG production. Concentration of Anti-PAG was 1.192 μg with titer of 1.044. Anti-PAG derived from rabbits recognized Standard PAG antigen (bovine PAG MDBiomed cat. 101-7963-13-3) and PAG isolate derived from previous research. The reaction of antigen antibody is the basic structure of creating a gestation detection kit. Anti-PAG is expected to be the molecular marker in developing a gestation detection kit in the near future.
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Vigueras-Villaseñor, Rosa María, Martín Alejandro Fuentes-Cano, Margarita Chávez Saldaña, et al. "Fetal and Postnatal Nicotine Exposure Modifies Maturation of Gonocytes to Spermatogonia in Mice." Analytical Cellular Pathology 2020 (December 15, 2020): 1–14. http://dx.doi.org/10.1155/2020/8892217.

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Studies in laboratory animals have shown that male offspring from dams, exposed to nicotine during pregnancy and postnatal periods, show alterations in fertility, although the origin of this is still uncertain. In this study, we examined in a mouse model if the process of gonocyte maturation to spermatogonia was affected in male offspring from dams with nicotine administration during pregnancy and postnatal periods. BALB/C mice, with and without nicotine administrations in pregnancy and postnatal periods, were studied. The animals were euthanized at 3, 7, 10, 16, and 35 days postpartum (dpp). Testicular tissue samples were processed for histological, ultrastructural, and immunohistochemical studies; and testicular lipoperoxidation was determined. It was observed that in the nicotine-exposed animals, there was increased apoptosis and a reduction in the number of gonocytes that matured to spermatogonia. This gonocyte-spermatogonia maturation reduction was associated with a greater immunoreactivity to nicotinic acetylcholine receptors in the germ cells. Lipoperoxidation was similar in both groups until 16 dpp, with significant reduction at 35 dpp. Our findings suggest that nicotine intake during pregnancy and postnatal periods can affect the process of maturation of gonocytes to spermatogonia and the pool of available spermatogonia for spermatogenesis.
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Hansen, Peter J. "Implications of Assisted Reproductive Technologies for Pregnancy Outcomes in Mammals." Annual Review of Animal Biosciences 8, no. 1 (2020): 395–413. http://dx.doi.org/10.1146/annurev-animal-021419-084010.

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Development of assisted reproductive technologies has been driven by the goals of reducing the incidence of infertility, increasing the number of offspring from genetically elite animals, facilitating genetic manipulation, aiding preservation and long-distance movement of germplasm, and generating research material. Superovulation is associated with reduced fertilization rate and alterations in endometrial function. In vitro production of embryos can have a variety of consequences. Most embryos produced in vitro are capable of establishing pregnancy and developing into healthy neonatal animals. However, in vitro production is associated with reduced ability to develop to the blastocyst stage, increased incidence of failure to establish pregnancy, placental dysfunction, and altered fetal development. Changes in the developmental program mean that some consequences of being produced in vitro can extend into adult life. Reduced competence of the embryo produced in vitro to develop to the blastocyst stage is caused largely by disruption of events during oocyte maturation and fertilization. Conditions during embryo culture can affect embryo freezability and competence to establish pregnancy after transfer. Culture conditions, including actions of embryokines, can also affect the postnatal phenotype of the resultant progeny.
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Hennessy, Annemarie, Adrian Gillin, and John Horvath. "Cardiovascular Research in Pregnancy: The Role of Animal Models." Hypertension in Pregnancy 12, no. 3 (1993): 413–37. http://dx.doi.org/10.3109/10641959309042862.

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Dissertations / Theses on the topic "Pregnancy in animals – Research"

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Linden, Danitsja Stephanie van der. "Ewe size and nutrition during pregnancy : effects on metabolic and productive performance of the offspring : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science at Massey University, Turitea, Palmerston North, New Zealand." Massey University, 2010. http://hdl.handle.net/10179/1343.

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Exposure of the fetus to adverse conditions in utero may result in developmental adaptations that alter metabolism and postnatal growth of the offspring. This thesis investigated the effects of dam size and nutrition during pregnancy on growth, metabolic function and lactational and productive performance of the female offspring to two years of age. Four-hundred and fifty heavy (60.8 kg ± 0.18) and 450 light (42.5 kg ± 0.17) dams were randomly allocated to ad libitum or maintenance nutritional regimens from days 21 - 140 of pregnancy, under pastoral grazing conditions. From one week prior to lambing, all dams were fed ad libitum until weaning. After weaning, female progeny were managed and fed under pastoral conditions as one group. Maternal nutrition during pregnancy affected lamb growth to weaning, however, after weaning lamb growth was affected by dam size. Dam size had no effect on glucose metabolism, adrenal function or fat metabolism in 16-month-old female twin offspring. Dam nutrition during pregnancy had a minor effect on glucose metabolism and no effect on adrenal function or lipolysis, however, it did possibly affect gluconeogenesis and/or glycogenolysis, with increased glucose production in ewes born to maintenance-fed dams. Ewes born to dams fed maintenance showed greater milk production, lactose percentage, lactose and crude protein yield. Ewes born to heavy dams showed greater milk production and lactose yield. Dam size had no effect on reproductive performance of the female offspring. Being born to a larger dam showed no advantages over being born to smaller dams, for number of lambs born and weight of lambs at birth and weaning. ‘Grand’dam maintenance nutrition increased lamb birth and weaning weight and lamb growth rates of the ‘grand’offspring. Ewes born to maintenance-fed dams could have an advantage over ewes born to ad libitum-fed dams in physiological stressful situations in life as their liver may be able to supply more glucose to support their growing conceptus and milk production to increase the chances of survival of their offspring. These results indicate that it is possible to programme the offspring by feeding their dams differently during pregnancy under grazing conditions. With a better understanding of how offspring can be programmed through different maternal nutritional regimens, it may be possible to significantly increase the production potential of the New Zealand ewe population.
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Campbell, Regenia Beth Phillips. "Arrested and Aberrant: Effects of Amoxicillin in a Murine Model of Chlamydial Infection." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/2269.

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Chlamydia trachomatis is the most common sexually transmitted bacterial disease agent worldwide, and, though frequently asymptomatic, can cause extreme pathology including infertility. Chlamydial species exhibit a unique biphasic developmental cycle. Once attached to a cell surface, infectious elementary bodies (EB) are internalized within an inclusion, the membrane-bound structure in which EB transform to noninfectious, replicable reticulate bodies (RB). After multiple rounds of division, RB condense to form EB, which are released and can infect new host cells. In culture, exposure to stressors, such as beta-lactam antibiotics, induce chlamydiae to reversibly detour from normal development into a noninfectious, viable state termed persistence. Cell culture data suggest that persistent forms are resistant to azithromycin (AZM), a front-line antibiotic, and are able to alter the host transcriptome. Though persistence has been described in culture for over 50 years, whether or not it: i) occurs in vivo; and ii) influences chlamydial pathogenesis, transmission and therapy has remained unresolved. To address these questions, we developed an animal model of persistent chlamydial infection using amoxicillin (AMX) treatment. AMX exposure decreased shedding of infectious chlamydiae in C. muridarum-infected mice without affecting chlamydial viability, demonstrating the presence of persistent chlamydiae. Shedding of infectious EB resumed following AMX cessation. Shedding data and microarray analyses suggested that host immunity might limit chlamydia’s exit from persistence in our model. Thus, we hypothesized that cyclophosphamide (CTX) treatment would increase the magnitude of chlamydial shedding observed after AMX-treatment cessation. CTX treatment increased post-AMX shedding by more than 10-fold compared to AMX-only controls. To determine whether persistent chlamydiae are resistant to antibiotic eradication in vivo, we induced persistence by administering AMX and treated mice with various AZM dosing regimes. Persistently infected mice demonstrated increased treatment failure following AZM therapy compared to productively infected controls. These data suggest that persistent chlamydiae are refractory to treatment in vivo and provide an explanation for the observation that treatment fails in some patients. In addition to creating the first fully characterized, experimentally tractable, in vivo model of chlamydial persistence, these experiments provide evidence that persistent/stressed chlamydial forms may serve as a long-term reservoir of infectious organisms in vivo.
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Staufer, Lorry E. "Teen pregnancy prevention programs a systematic review of effects on pregnancy rates /." [Denver, Colo.] : Regis University, 2008. http://165.236.235.140/lib/LStaufer2008.pdf.

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Schuessler, Thomas F. "A computer controlled research ventilator for small animals /." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69704.

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Understanding the mechanical properties of the respiratory system is an important task in pulmonary physiology. Current research often involves small mammals (mice, rats or guinea pigs) which are easily obtained in large numbers as pure bred strains, thus allowing statistically reliable results with minimal inter-animal variation to be obtained. However, due to the small flow amplitudes involved, the input impedance of common flow measurement devices is often too low to reliably measure tracheal flow. Furthermore, experimental setups are usually very limited in the types of volume, pressure or flow perturbations they can apply to the respiratory system. The computer controlled research ventilator for small animals described here overcomes both problems. Tracheal flow is estimated from the position of the ventilator piston and the pressure within the cylinder. Furthermore, the setup is capable of applying any desired volume perturbation with a bandwidth up to 55 Hz.
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Olszynko-Gryn, Jesse. "Pregnancy testing in Britain, c.1900-67 : laboratories, animals and demand from doctors, patients and consumers." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708529.

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Siegel, Angeline M. "Unspoken connections| Scientists' intersubjective experiences with animals." Thesis, Saybrook University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3711355.

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<p> Little is known about the scientist-animal relationship; therefore, the aim of this study was to learn how moments of intersubjectivity, or "oneness" are created and experienced by scientists. It is by appreciating the risks and vulnerabilities intrinsic to human-animal relationships that propel the present investigation. The current cultural bias of valuing objectification and detachment as the predominant form of scientific investigation overlooks relational subtleties intrinsic to deriving meaning from humananimal studies. By examining scientists and their descriptions of intersubjectivity with their animal participants, a greater understanding of society's philosophical and ethical deliberations on the human-animal relationship may be revealed. An exploratory, sequential mixed-method design was utilized to phenomenologically examine intersubjectivity, as well as to measure the prevalence of its dimensions within the larger academic population. Phenomenological analysis from ten interviews identified humananimal intersubjectivity as having four significant phases: <i>joint mindfulness, synchronized embodiment, intrinsic belonging </i>, and <i>transcendental awareness</i>. Spearman correlational analysis from fifty-four responses to the online survey supported these findings, as well as identified a potential link with the variables of proximity (r<sub> s</sub> = .469, p &lt; .05, n=25), closeness (r<sub>s</sub> = .483, p &lt; .01, n=25), similarity (r<sub>s</sub> = .483, p &lt; .01, n=25) and embodied awareness (r<sub>s</sub> = .421, p &lt; .01, n=25) that account for variation in the scientific population. When examining past behavior as it related to current scientific practices, gender differences emerged that resemble those reported by neuroanatomical studies. Lastly, further mixed analysis identified academic and cultural risks that were met by employing concealment and silencing strategies. These results add valuable depth in the interpretation of intersubjectivity and its relationship with scientific behavior, as well as insight into the role of intersubjectivity within ethical and philosophical debates.</p>
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Ali, Cairo F. "Animal rights and animal research." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1371556393.

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Birtwell, B. "The experience of pregnancy for vulnerable women." Thesis, Canterbury Christ Church University, 2012. http://create.canterbury.ac.uk/11179/.

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Section A is a literature review focused on critically evaluating theory and research relating to three variables commonly experienced by vulnerable pregnant women. These pose a ‘risk’ to unborn babies and include: social exclusion, stress and poor attachment (NICE, 2010). Selected interventions for reducing the known ‘risks’ are critically evaluated, as well as qualitative studies into the experiences of pregnancy for vulnerable women. Gaps in existing theory and research are discussed, leading to suggestions for future research, including further qualitative study of vulnerable women’s experiences of pregnancy. Section B presents a study into eight vulnerable women’s experiences of pregnancy and the Mellow Bumps antenatal intervention. Interpretative Phenomenological Analysis was used to make sense of participants’ experiences. The analysis revealed pregnancy was a time of reflection, when participants felt their bodies were being taken over, they felt more emotional than usual, relationships were important, and new identities developed. Pregnancy was a “normalising” experience, which provided an opportunity to build positive representations of the self. Mellow Bumps supported this. Implications for clinical practice and future research are discussed.
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DiBenedetto, Lynn M. "An Examination of the Hypothalamo-neurohypophysial System of the Rat: Restoration of the Vasopressinergic System." eScholarship@UMMS, 1997. https://escholarship.umassmed.edu/gsbs_diss/169.

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The hypothalamo-neurohypophysial model has been studied for many years. Of note, when the axons of the magnocellular, peptidergic neurons of the supraoptic nucleus (SON) and paraventricular nucleus (PVN) are transected or crushed, varying degrees of polydipsia and polyuria ensue as the result of measurable losses of vasopressin (AVP) within the organism's circulation. Following insult, these hypothalamic cells show a remarkable capacity to reorganize themselves within the proximal areas of the infundibular stalk and median eminence and form what has come to be known as a new 'mini neural lobe' . While the surviving neurons sprout new projections toward the level of the external zone, vascular hypertrophy is marked throughout the new neurohypophysis and new neurohemal contacts have been identified (at the ultrastructural level) associated with these vessels. In parallel with this vascular hypertrophy is a measurable re-release of vasopressin into the circulation. This new 'mini neural lobe' now has the morphological and physiological appearance of an intact neural lobe and is capable of releasing AVP in response to changes in water balance. While the ability of these axons to reorganize is more characteristic of the peripheral nervous system (PNS), this model system provides an unique opportunity to study axonal regeneration of the central nervous system (CNS). Not only the mechanisms underlying the restoration of AVP function following axotomy but the extent to which various magnocellular neuron populations are involved in the regenerative process may also be analyzed. Before attempting to identify putative markers associated with this regenerative process, it was necessary to carefully characterize the system following axonal injury. Using Sprague Dawley rats, we repeated previous physiological studies which had examined the intake of water and output of urine following hypophysectomy. In addition, we also correlated the restoration of water balance with the return of AVP release, as measured by radioimmunoassay. These data defined a temporal framework in which magnocellular AVP regeneration occurs. As a result of repeating these physiological studies, we noted several inconsistencies between other previously published work. First, the time course of AVP recovery did not agree with other published results, nor did the first appearance of AVP immunoreactivity . We did not observe a complete recovery of water balance as previously reported and the degree of magnocellular death was inconsistent with other reports. In light of these many conflicting observations between several historical reports and our own results, we did a basic physiological re-characterization of the hypothalamo-neurohypohysial system following hypophysectomy. By means of immunohistochemistry, we also demonstrated the re-appearance of AVP within the new the 'mini neural lobe ' concomitant with the increased appearance of synapsin I, a marker associated with the presence of mature and presumably functioning synapses to be no sooner than 28 days following surgical removal of the hypophysis. Immunocytochemistry was also used in conjunction with retrograde fluorescent labeling to extend the previous studies and include a 2-D analysis of cell survival throughout the PVN and SON following hypophysectomy or neurohypophysectomy. As reported previously, magnocellular neuronal loss is greater within the SON, particularly the hypophysectomized subject, and less so within the PVN; again with the greater loss in the PVN of the hypophysectomized animal. Based upon our observations and other recent reports, we suggest the possibility that some cells of the hypothalamo-neurohypophysial system or some other extrahypothalamic cell population may be capable of expressing vasopressin in response to neurohypophysectomy. We provide initial evidence that glial cells of the third ventricle may indeed be involved. Finally, one of the ultimate goals of using this as a model system of CNS regeneration is to understand the underlying mechanisms and components essential to central nervous tissue regeneration. Toward that end I have been involved with the initial studies to optimize an adenovirus delivery system which will be capable of incorporating various putative neurotransmitter and/or peptide anti-sense messages, being injected into the neurohypophysis and transported back into the cells of the hypothalamo-neurohypophysial system. Once these antisense sequences are expressed by the cells following axotomy, the sequence of expression of various proteins in response to injury may be elucidated.
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Fletcher, Tifani R., Andrea D. Clements, Lana McGrady, and Beth A. Bailey. "Religious Commitment and Depression During Pregnancy." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/7265.

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Books on the topic "Pregnancy in animals – Research"

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Hau, Jann, ed. Pregnancy Proteins in Animals. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167.

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Hughes, Lizanne S. Research helping animals. Foundation for Biomedical Research, 1993.

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Than, Gabor N. Advances in pregnancy-related protein research: Functional and clinical applications. CRC Press, 1993.

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Michael, Sims. In the womb: Animals. National Geographic, 2009.

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Ontario. Ministry of Agriculture and Food. The animals for research act. Ministry of Agriculture and Food, 1993.

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Society, Physiological. Using animals in biomedical research. The Physiological Society., 1993.

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Darenius, Kerstin. Early pregnancy loss in the mare. Sveriges Lantbruksuniversitet, 1992.

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Mains, Richard C. Rodent research. NASA ISS Program Science Office, 2015.

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Miska, John P. Animal diseases research, 1939-1985: A bibliography of research papers by scientists at animal Diseases Research Institute, Lethbridge. Animal Diseases Research Institute, 1985.

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Bennett, B. T. Essentials for animal research: A primer for research personnel. National Agricultural Library, 1990.

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Book chapters on the topic "Pregnancy in animals – Research"

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Jainudeen, M. R., and E. S. E. Hafez. "Pregnancy Diagnosis." In Reproduction in Farm Animals. Lippincott Williams & Wilkins, 2016. http://dx.doi.org/10.1002/9781119265306.ch28.

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Cusack, Carmen M. "Animals." In Laws Relating to Sex, Pregnancy, and Infancy. Palgrave Macmillan US, 2015. http://dx.doi.org/10.1057/9781137505194_5.

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Martin, B., M. Bonnin, P. Silberzahn, and F. Xavier. "TRANSCORTIN ACTIVITY DURING PREGNANCY." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-031.

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Björkman, N. "COMPARATIVE STRUCTURAL AND FUNCTIONAL FEATURES OF THE MAMMALIAN PLACENTA." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-002.

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Chard, T. "PREGNANCY PROTEINS IN THE HUMAN - BIOLOGICAL AND CLINICAL SIGNIFICANCE." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-003.

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G.Grudzinskas, J., J. G. Westergaard, and B. Teisner. "CLINICAL ASPECTS OF PLACENTAL PROTEIN MEASUREMENTS IN EARLY PREGNANCY AND ITS COMPLICATIONS." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-004.

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Teisner, B. "“NORMAL” PLASMA PROTEINS DURING PREGNANCY." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-005.

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B. Hertz, J., and P. Schultz-Larsen. "PLACENTAL PROTEINS IN THREATENED ABORTION." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-006.

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Toftager-Larsen, K. "CARBOHYDRATE MICROHETEROGENEITY OF MATERNAL SERUM AFP IN PREGNANCY." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-007.

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G. Rasmussen, A., B. Nørgaard-Pedersen, and J. Hangaard. "PRENATAL DIAGNOSTIC SIGNIFICANCE OF A SPECIFIC QUANTITATIVE IMMUNOASSAY FOR ACETYLCHOLINESTERASE IN AMNIOTIC FLUID." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-008.

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Conference papers on the topic "Pregnancy in animals – Research"

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Zuo, Guohua. "Research of Animals' Subconscious Art Creation." In 2016 5th International Conference on Social Science, Education and Humanities Research. Atlantis Press, 2016. http://dx.doi.org/10.2991/ssehr-16.2016.20.

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Zhu, Gang-Jiao, Ling Qi, Chang Xia, et al. "The effects of physical activity mediated in pregnancy outcomes during pregnancy." In Proceedings of the 2019 5th International Conference on Humanities and Social Science Research (ICHSSR 2019). Atlantis Press, 2019. http://dx.doi.org/10.2991/ichssr-19.2019.99.

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Antipova, Yulia Evgenevna. "Teratoma and pregnancy: a case from practice." In XI International Research-to-practice conference, chair Mariia Gennadevna Efremova. TSNS Interaktiv Plus, 2017. http://dx.doi.org/10.21661/r-464016.

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Feola, Andrew, Marianna Alperin, Pamela Moalli, and Steven Abramowitch. "Characterizing the Maternal Adaptations of Pregnancy and Recovery Following Vaginal Delivery in the Rodent Model." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19224.

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Pelvic organ prolapse and urinary incontinence are common conditions in women that significantly diminish quality of life. Vaginal delivery and maternal birth injury are the number one risk factors for the development of pelvic floor disorders. The goal of this study was to characterize maternal adaptations throughout pregnancy and recovery after vaginal delivery in terms of the passive quasi-static mechanical properties of the vagina using a rodent model. Virgin (n = 8), mid-pregnant (n = 7, day 15–16), late-pregnant (n = 7, day 20–21), immediate postpartum (n = 8, &lt;2 hours post delivery), and 4 week postpartum (n = 6) Long-Evans female rats were utilized in this study. The mechanical properties (tangent modulus, tensile strength, ultimate strain, and strain energy density) were quantified by testing longitudinal sections of vaginal tissue to failure. The tangent modulus of virgin animals (25.1±5.1 MPa) was significantly higher compared to mid-pregnant (11.7±7.7 MPa, p = 0.003), late-pregnant (7.9±4.0 MPa, p&lt;0.001), and immediate postpartum (8.5±4.7 MPa, p = 0.001) animals. A similar trend was also observed in the tensile strength, whereas the ultimate strain increased throughout pregnancy until the time of vaginal delivery. Recovery was observed four weeks postpartum as no significant difference was found from virgin animals for any of the parameters. This study has shown a significant decrease in the tangent modulus and tensile strength along with an increase in the ultimate strain of longitudinal sections of vaginal tissue throughout pregnancy. These maternal adaptations are likely to increase the overall distensibility of the vagina and allow for vagina delivery with minimal injury. This process appears to be effective in the rodent model as the properties recovered to virgin levels by 4 weeks. In the future, we hope to alter these adaptations or exceed them in order to study the risk and impact of birth injury in this model.
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Pachova, Darina. "Reading aloud during the pregnancy – a Bulgarian research." In The 4th Human and Social Sciences at the Common Conference. Publishing Society, 2016. http://dx.doi.org/10.18638/hassacc.2016.4.1.198.

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Conrad, David, John Emond, and Louis Stodieck. "Automation for improved physiological research in microgravity using laboratory animals." In Space Programs and Technologies Conference. American Institute of Aeronautics and Astronautics, 1996. http://dx.doi.org/10.2514/6.1996-4326.

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Clemente, Miriam, Beatriz Rey, Aina Rodríguez-Pujadas, et al. "fMRI assessment of small animals’ phobia using virtual reality as stimulus." In ICTs for improving Patients Rehabilitation Research Techniques. IEEE, 2013. http://dx.doi.org/10.4108/icst.pervasivehealth.2013.252180.

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PRZYBYLAK, Michal. "ANIMALS IN THE ARMY. ON BANNERS AND IN COMBAT." In The 5th International Conference on Research in Behavioral and Social Science. acavent, 2018. http://dx.doi.org/10.33422/5icrbs.2018.12.88.

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Miermont, Anne, and Priscilla Furth. "Abstract A6: Stat5a and pregnancy protection in the CERM mouse model." In Abstracts: Frontiers in Cancer Prevention Research 2008. American Association for Cancer Research, 2008. http://dx.doi.org/10.1158/1940-6207.prev-08-a6.

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Zaiki, F. W. A., S. M. Dom, H. R. A. Razak, and H. F. Hassan. "Prenatal Ultrasound Heating Influences on Fetal Weight Assessment of Oryctolagus cuniculus Throughout Pregnancy." In Bioscience and Medical Research 2013. Science & Engineering Research Support soCiety, 2013. http://dx.doi.org/10.14257/astl.2013.33.02.

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Reports on the topic "Pregnancy in animals – Research"

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Osborne, Nikki. Research Integrity: A primer on research involving animals. Edited by Josephine Woodhams. UK Research Integrity Office (UKRIO), 2019. http://dx.doi.org/10.37672/ukrio.2019.01.animals.

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Osborne, Nikki. Research Integrity: A primer on research involving animals. UKRIO, 2021. http://dx.doi.org/10.37672/ukrio.2021.02.animals.

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This document seeks to highlight the abundance of information regarding good practice, responsible conduct and integrity that relates to animal use in research. General awareness of these across the Life Science research community is highly variable. However, many of the documents referenced here offer useful tools to assist in the review of training, support and/or mentoring to equip students and staff with the necessary knowledge and skills that they will need to achieve, or work towards achieving, the expectations described above.
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Zurlo, Joanne. Institute of Laboratory Animals Research (ILAR). Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416653.

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Kokolova, L. M., L. Y. Gavrilieva, S. M. Stepanova, S. V. Dulova, and I. I. Romanov. RESEARCH OF PARASITIC DISEASES IN FISHING ANIMALS IN THE ECOSYSTEM OF THE FAR NORTH. Ljournal, 2019. http://dx.doi.org/10.18411/2108-1986-gelmint.

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Nwala, Emmanuel, Udochisom Anaba, Pooja Sripad, Salisu Ishaku, and Charlotte Warren. Feasibility and acceptability of community health extension workers to identify and treat hypertension associated with pregnancy: Implementation research report. Population Council, 2019. http://dx.doi.org/10.31899/rh11.1007.

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Stassen, Elsbeth N. New balance In animal husbandry : Farewell address upon retiring as Professor of Animals and Society at Wageningen University & Research on 21 November 2019. Wageningen University & Research, 2019. http://dx.doi.org/10.18174/514446.

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Pounds, L. R., P. D. Parr, and M. G. Ryon. Resource management plan for the Oak Ridge Reservation. Volume 30, Oak Ridge National Environmental Research Park natural areas and reference areas--Oak Ridge Reservation environmentally sensitive sites containing special plants, animals, and communities. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10179639.

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P., BASTIAENSEN. Triage in the trenches, for the love of animals : a tribute to veterinarians in the First World War. O.I.E (World Organisation for Animal Health), 2018. http://dx.doi.org/10.20506/bull.2018.nf.2883.

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On the occasion of the centenary of the First World War, remembered across the world from 2014 until the end of 2018, many aspects and experiences of this global conflict have been re-examined or brought to light for the first time, as we honour the memory of those estimated 16 million soldiers and civilians who perished in what was then known as the ‘Great War’, or the ‘War to End All Wars’. So many of these died on the infamous fields of Flanders, where Allied and Central Forces dug themselves into trenches for the better part of four years. Over the past few years, new research has brought to light many insights into the plight of animals in this War, which – for the younger readers amongst you – was fought at the dawn of motorised warfare, using anything powered by two or four feet or paws, from the homing pigeons delivering secret messages across enemy lines, to the traction provided by oxen and mules to pull cannons and other heavy artillery, to the horses of the cavalry. Not least among these roles was the supply of animal protein to the troops, whether this came through the specific designation of animals for this purpose or as the result of a failed attempt at delivering any of the above services. Several leading publications today have documented the role (and suffering) of animals in ‘La Grande Guerre’. Less so the role of veterinarians in the ‘War to End All Wars’. Who were they? How many? How were they organised? What did they do, on either side of the enemy lines? The present article is a humble attempt to shed some light on these veterinary colleagues, based on available, mostly grey, literature…
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Baek, Carolyn, and Naomi Rutenberg. Addressing the family planning needs of HIV-positive PMTCT clients: Baseline findings from an operations research study. Population Council, 2005. http://dx.doi.org/10.31899/hiv14.1000.

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Preventing unintended pregnancy among HIV-positive women is an effective approach to reducing pediatric HIV infection and vital to meeting HIV-positive women’s sexual and reproductive health needs. Although contraceptive services for HIV-positive women is one of the cornerstones of a comprehensive program for prevention of mother-to-child transmission of HIV (PMTCT), a review of PMTCT programs found that implementers have not prioritized family planning (FP). While there is increasing awareness about the importance of FP and HIV integration, data about FP from PMTCT clients are lacking. The Horizons Program is conducting an operations research study testing several community-based strategies to reduce mother-to-child transmission of HIV in a densely settled urban slum in Nairobi, Kenya. Strategies being piloted include moving PMTCT services closer to the population via a mobile clinic and increasing psychosocial support for HIV-positive women. This research update presents key findings about FP at PMTCT sites, including the interaction between providers and clients as well as HIV-positive women’s fertility desires and demand for contraceptives, from the baseline cross-sectional survey and qualitative interviews with postpartum women.
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Gidengil, Courtney, Matthew Bidwell Goetz, Margaret Maglione, et al. Safety of Vaccines Used for Routine Immunization in the United States: An Update. Agency for Healthcare Research and Quality (AHRQ), 2021. http://dx.doi.org/10.23970/ahrqepccer244.

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Objective. To conduct a systematic review of the literature on the safety of vaccines recommended for routine immunization in the United States, updating the 2014 Agency for Healthcare Research and Quality (AHRQ) report on the topic. Data sources. We searched MEDLINE®, Embase®, CINAHL®, Cochrane CENTRAL, Web of Science, and Scopus through November 9, 2020, building on the prior 2014 report; reviewed existing reviews, trial registries, and supplemental material submitted to AHRQ; and consulted with experts. Review methods. This report addressed three Key Questions (KQs) on the safety of vaccines currently in use in the United States and included in the Centers for Disease Control and Prevention’s (CDC) recommended immunization schedules for adults (KQ1), children and adolescents (KQ2), and pregnant women (KQ3). The systematic review was supported by a Technical Expert Panel that identified key adverse events of particular concern. Two reviewers independently screened publications; data were extracted by an experienced subject matter expert. Studies of vaccines that used a comparator and reported the presence or absence of adverse events were eligible. We documented observed rates and assessed the relative risks for key adverse events. We assessed the strength of evidence (SoE) across the existing findings from the prior 2014 report and the new evidence from this update. The systematic review is registered in PROSPERO (CRD42020180089). Results. A large body of evidence is available to evaluate adverse events following vaccination. Of 56,608 reviewed citations, 189 studies met inclusion criteria for this update, adding to data in the prior 2014 report, for a total of 338 included studies reported in 518 publications. Regarding vaccines recommended for adults (KQ1), we found either no new evidence of increased risk for key adverse events with varied SoE or insufficient evidence in this update, including for newer vaccines such as recombinant influenza vaccine, adjuvanted inactivated influenza vaccine, and recombinant adjuvanted zoster vaccine. The prior 2014 report noted a signal for anaphylaxis for hepatitis B vaccines in adults with yeast allergy and for tetanus, diphtheria, and acellular pertussis vaccines. Regarding vaccines recommended for children and adolescents (KQ2), we found either no new evidence of increased risk for key adverse events with varied SoE or insufficient evidence, including for newer vaccines such as 9-valent human papillomavirus vaccine and meningococcal B vaccine. The prior 2014 report noted signals for rare adverse events—such as anaphylaxis, idiopathic thrombocytopenic purpura, and febrile seizures—with some childhood vaccines. Regarding vaccines recommended for pregnant women (KQ3), we found no evidence of increased risk for key adverse events with varied SoE among either pregnant women or their infants following administration of tetanus, diphtheria, and acellular pertussis vaccines during pregnancy. Conclusion. Across this large body of research, we found no new evidence of increased risk since the prior 2014 report for key adverse events following administration of vaccines that are routinely recommended. Signals from the prior report remain unchanged for rare adverse events, which include anaphylaxis in adults and children, and febrile seizures and idiopathic thrombocytopenic purpura in children. There is no evidence of increased risk of adverse events for vaccines currently recommended in pregnant women. There remains insufficient evidence to draw conclusions about some rare potential adverse events.
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