Relevant bibliographies by topics / Pregnane analogues

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Pregnane analogues'

Author: Grafiati
Published: 4 June 2021
Last updated: 15 February 2022

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Journal articles on the topic "Pregnane analogues"

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Slavíková, Barbora, Alexander Kasal, Hana Chodounská та Zdena Krištofíková. "3α-Fluoro Analogues of "Allopregnanolone" and Their Binding to GABAA Receptors". Collection of Czechoslovak Chemical Communications 67, № 1 (2002): 30–46. http://dx.doi.org/10.1135/cccc20020030.

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(Diethylamino)sulfur trifluoride (DAST) was used for the preparation of 3α-fluorides (e.g., 3α-fluoro-5α-pregnane-12,20-dione, 3α-fluoro-16α-[(methoxycarbonyl)methyl]-5α-pregnan-20-one, methyl 3α-fluoro-5α-androstane-17β-carboxylate, 3α-fluoro-5β-pregnan-20-one) from the corresponding 3β-alcohols and for the preparation of 3,3-difluorides from 3-ketones (e.g., 3,3-difluoro-5α-pregnan-20-one). Boron trifluoride etherate was used for the conversion of an epoxide into 3α-fluoro-2β-hydroxy-5α-pregnan-20-one. The in vitro binding of the 3α-fluorides and the corresponding 3α-alcohols to the GABAA re
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Kohout, Ladislav, Alexander Kasal, and Miroslav Strnad. "Pregnane-Type Brassinosteroids with a Four-Carbon Ester Functionality in Position 20." Collection of Czechoslovak Chemical Communications 61, no. 6 (1996): 930–40. http://dx.doi.org/10.1135/cccc19960930.

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Analogues of brassinolide and castasterone, containing an ester functionality with four carbon atoms in the position 20 of the pregnane skeleton, have been prepared. In the bean second internode assay the most effective compounds were (20R)-2α,3α,20-trihydroxy-5α-pregnan-6-one 20-isobutyrate (6d) and (20R)-2α,3α,20-trihydroxy-B-homo-7-oxa-5α-pregnan-6-one 20-isobutyrate (7d). On the other hand, (20R)-2α,3α,20-trihydroxy-B-homo-6-oxa-5α-pregnan-7-one 20-heptafluorobutyrate (8) was the first compound with the retarding effect in the same test.
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Rivera, Daniel G., and Francisco Coll. "Synthesis and preliminary bioactivity evaluation of new pregnane brassinosteroid-like compounds." Canadian Journal of Chemistry 83, no. 8 (2005): 1084–92. http://dx.doi.org/10.1139/v05-051.

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Seven new pregnane compounds bearing some representative A- and B-ring brassinosteroid functions, as well as hydrogen bond donor and acceptor ones on the D ring, were efficiently synthesized. The obtained compounds did not show remarkable plant growth-promoting activity in the radish hypocotyl elongation and cotyledon expansion bioassays, however, introducing oxygen and amino functions on the D ring led to an enhancement of the bioactivity. The 16β-functionalized pregnane brassinosteroid-like compounds were slightly more active than the 16α-functionalized ones.Key words: steroids, brassinoster
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Sui, Yipeng, Ni Ai, Se-Hyung Park, et al. "Bisphenol A and Its Analogues Activate Human Pregnane X Receptor." Environmental Health Perspectives 120, no. 3 (2012): 399–405. http://dx.doi.org/10.1289/ehp.1104426.

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Kohout, Ladislav, and Miroslav Strnad. "Brassinosteroids with Ester Function with Five Carbon Atoms at the 20 Position." Collection of Czechoslovak Chemical Communications 57, no. 8 (1992): 1731–38. http://dx.doi.org/10.1135/cccc19921731.

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Pregnane analogues of brassinolide and castasterone have been prepared which have an ester function with five carbon atoms at the 20 position. When tested by the bean second internode bioassay, the most efficient substance is VIII.
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Murayama, Eigoro, Katsuhito Miyamoto, Kiyoshige Ochi, and Noboru Kubodera. "Synthesis and immunoregulating activity of vitamin D analogues bearing pregnane side chains." Bioorganic & Medicinal Chemistry Letters 2, no. 10 (1992): 1289–92. http://dx.doi.org/10.1016/s0960-894x(00)80232-2.

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Shao, Yuting, Yan Zhao, Hong Zhang, et al. "A New Immunosuppressive Pregnane Glycoside and Two Known Analogues from Epigynum cochinchinensis." Natural Product Communications 13, no. 6 (2018): 1934578X1801300. http://dx.doi.org/10.1177/1934578x1801300604.

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Phytochemical investigation of the ethyl acetate soluble fraction from the leaves of Epigynum cochinchinensis led to the isolation of one new C21 pregnane glycoside, epigycoside C (1), along with two known analogues epigycoside A (2) and epigynoside G (3). Their structures were elucidated on the basis of extensive spectroscopic techniques. The in vitro immunosuppressive activity of compound 1 was evaluated against concanavalin A (Con A)- and lipopolysaccharides (LPS)-stimulated proliferation of mice splenocytes. Compound 1 displayed significant immunosuppressive activities in a dose-dependent
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Rivera, Daniel G., Francisco Coll, and Fredy León. "Synthesis of pregnane ketols as metabolic precurs ors of analogues of plant growth regulators." Journal of Chemical Research 2004, no. 4 (2004): 284–85. http://dx.doi.org/10.3184/0308234041209239.

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Lau, Aik Jiang, and Thomas K. H. Chang. "3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease." Pharmacological Research 100 (October 2015): 64–72. http://dx.doi.org/10.1016/j.phrs.2015.07.031.

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Melin, P., J. Trojnar, B. Johansson, H. Vilhardt, and M. Åkerlund. "Synthetic antagonists of the myometrial response to vasopressin and oxytocin." Journal of Endocrinology 111, no. 1 (1986): 125–31. http://dx.doi.org/10.1677/joe.0.1110125.

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ABSTRACT With the aim of developing inhibitors of vasopressin-and oxytocin-induced uterine activity, 17 analogues of 1-deamino-oxytocin were synthesized by the solid-phase method. Modifications were made at positions 2, O-methyltyrosine (Tyr(OMe)) and O-ethyltyrosine (Tyr(OEt)),d-Tyr,d-Tyr(OEt),d-Trp; 4, Val,Thr and 8, Orn,Cit,Arg,d-Arg. The analogues were tested for antiuterotonic activity in vitro and in vivo in the rat and in vitro on myometrial strips from non-pregnant women and pregnant women at term. Their selectivity was also investigated in blood pressure and antidiuretic bioassays in
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Dissertations / Theses on the topic "Pregnane analogues"

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Lind, Karin, and Maria Trång. "Effekten av kinesiotejpning på aktivitetsförmåga och smärta hos gravida med pelvic girdle pain – en pilotstudie." Thesis, Uppsala University, Physiotheraphy, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-126701.

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<p><strong> </strong></p><p>Syftet var att undersöka om kinesiotejpning kunde påverka aktivitetsförmåga och smärta hos gravida kvinnor med pelvic girdle pain. Studien var en single subjekt experimentell AB-design. Fyra kvinnor inkluderades i pilotstudien för behandling av pelvic girdle pain. Smärtan skattades och mättes med visuell analog skala. Aktivitetsförmågan mättes med Roland &  Morris disability questionnaire.</p><p>Resultatet visade att gällande aktivitetsförmåga kunde det med 95 % säkerhet ses en förbättring hos tre av kvinnorna. Gällande smärtskattningen kunde endast hos en kvinna på
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Krausová, Barbora. "Interakce steroidu s NMDA receptorem: Strukturně-aktivitní studie a vliv na mutované lidské formy NMDA receptorů." Doctoral thesis, 2018. http://www.nusl.cz/ntk/nusl-391367.

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N-methyl-D-aspartate (NMDA) receptors are glutamate-gated calcium permeable ion channels that play a key role in excitatory synaptic transmission and plasticity, and their dysfunction underlies several neuropsychiatric disorders. The overactivation of NMDA receptors by tonically increased ambient glutamate can lead to excitotoxicity, associated with various acute and chronic neurological disorders, such as ischemia, Alzheimer and Parkinson's disease, epilepsy or depression. On the opposite, NMDA receptor hypofunction is thought to be implicated in autism, schizophrenia, or intellectual disabil
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Book chapters on the topic "Pregnane analogues"

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Szabó, D., P. Gõcze, and G. Than. "PREGNANCY ASSOCIATED ʆ2-GLYCOPROTEIN ANALOGUES IN MONKEY AND DOG." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-037.

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Coulam, Carolyn, and Daniel Rukavina. "Immunomodulatory Analogies Between Trophoblastic and Cancer Cells and Their Hosts." In Cancer and Pregnancy. Springer London, 2001. http://dx.doi.org/10.1007/978-1-4471-0707-1_16.

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Bohn, Hans. "NEW PREGNANCY RELATED PROTEINS IN HUMANS AND THEIR ANALOGUES IN ANIMALS." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-027.

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Ron-El, R., E. Caspi, H. Nachum, et al. "Improved Pregnancy Rate in Ivf/Et by Combined Long-Acting GnRH Analogue and Gonadotropins." In GnRH Analogues in Reproduction and Gynecology. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0721-8_18.

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Ron-El, R., E. Caspi, H. Nachum, et al. "Improved Pregnancy Rate in IVF/ET by Combined Long-Acting GnRH Analogue and Gonadotropins." In GnRH Analogues in Cancer and Human Reproduction. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-2169-6_18.

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T. Waites, Gillian, and S. C. Bell. "STUDIES ON MURINE a1-PREGNANCY-ASSOCIATED PROTEIN (a1-PAP) AND ITS RAT ANALOGUE AND THEIR RELATIONSHIP TO HUMAN a2-PAG." In Pregnancy Proteins in Animals, edited by Jann Hau. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110858167-040.

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Yoshinaga, Koji, and Masahiko Fujino. "Hormonal Control of Implantation in the Rat: Inhibition by Luteinizing Hormone-Releasing Hormone and its Analogues." In Ciba Foundation Symposium 64 - Maternal Recognition of Pregnancy. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470720479.ch5.

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Vanhie, Arne, and Thomas D’Hooghe. "Endometriosis." In Oxford Textbook of Obstetrics and Gynaecology, edited by Sabaratnam Arulkumaran, William Ledger, Lynette Denny, and Stergios Doumouchtsis. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198766360.003.0045.

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Endometriosis is a chronic oestrogen-dependent gynaecological disease present in approximately 10% of women of reproductive age and up to 30–50% of women with infertility and/or pain. It is defined as the presence of endometrial-like tissue outside the uterus. The pathogenesis remains enigmatic but the most common hypothesis is Sampson’s theory of retrograde menstruation. Over the last decade, the roles of inflammation, angiogenesis, and the immune system have been well documented. Diagnosis of endometriosis is difficult since physical examination, ultrasonography, and magnetic resonance imaging can detect but not exclude the presence of endometriosis. Therefore, the gold standard for diagnosis of endometriosis remains laparoscopic visualization with histological confirmation. Medical treatment options are combined oral contraceptives, progestogens, or gonadotropin-releasing hormone analogues. Surgical management is necessary in patients who want to become pregnant or those who are refractory to medical treatment. These complex surgical procedures, with significant risks and recurrence rates, should be performed by experienced teams only.
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Brown, Stephen D. "Prenatal Counseling for Maternal–Fetal Surgery." In Reproductive Ethics in Clinical Practice, edited by Katie Watson and Julie Chor. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190873028.003.0018.

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This chapter analyzes potential biases and competing interests in prenatal counseling when conditions are diagnosed for which intrauterine surgery may be possible. Such counseling often occurs at the multidimensional interface of obstetrics and pediatrics. After considering clinical, social, and historical contexts of such counseling, the chapter presents a case that illustrates how physician demographics, interspecialty differences, divergent clinical experiences, and larger organizational factors may compound practice variation. It considers how biased counseling may influence patients’ decisions and questions whether value-neutral counseling is attainable when such fetal conditions are diagnosed. It concludes that declared commitments to value neutrality cannot insulate pregnant patients from biases and competing interests. In its recommendations, it discusses organizational responses analogous to conflict-of-interest policies. It further suggests that conversations between clinicians and patients that are mutually open about values may enhance rather than undermine patients’ ability to formulate decisions that most closely embody their true preferences.
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George, Elizabeth, and Karen Jackson. "Employment Rights and Duties, Statutory Office Holders, and Volunteers." In Blackstone's Guide to the Equality Act 2010. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198870876.003.0004.

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This chapter examines Part 5 of the Equality Act 2010, which prohibits discrimination, harassment, and victimization in employment and analogous situations. It contains provisions regarding those who are not strictly employees but who are also protected from discrimination in the course of performing their duties such as police officers, partners, barristers and advocates, and other office holders. Part 5 also contains the Occupational Pension Schemes provisions. Meanwhile, Chapter 3 of Part 5 contains the provisions relating to equal pay, pregnancy and maternity pay, restrictions on pay discussions, and gender pay gap information. The Act consolidates and replaces the previous anti-discrimination legislation which is largely replicated in the Act, with some notable amendments. These amendments are intended to unify the level of protection across all of the protected characteristics and to resolve any anomalies, for example around disability-related discrimination.
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Conference papers on the topic "Pregnane analogues"

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Terent'ev, S. S., V. I. Velikanov, A. V. Kljapnev, et al. "FEATURES COLOSTRAL IMMUNITY CALVES IN COMBINED STIMULATION PREGNANT COWS IMMUNOMODULATORS AND SYNESTROL2%." In "International Scientific and Practical Conference" THEORY AND PRACTICE OF VETERINARY PHARMACY, ECOLOGY AND TOXICOLOGY IN AIC ", dedicated to the centenary of the Department of Pharmacology and Toxicology, SPbSUVM. FSBEI HE St. Petersburg SUVM, 2021. http://dx.doi.org/10.52419/3006-2021-2-225-228.

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The purpose of our experiment was to study the effect of the combined administration of an immunomodulator and a synthetic analogue of estrone to cows 3-5 days before calving on the colostral immunity of calves. The result of the work showed that the calves obtained from such cows have a greater number of leukocytes, T-lymphocytes and B-lymphocytes at birth. A synthetic analogue of estrone probably cross the placenta and affect the fetus, which is reflected in the acceleration of the metabolism of the newborn. As a result, there was an accelerated assimilation of colostrum from the gastrointes
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