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1

LAZAREVA, A. YU, I. B. FATKULLINA, E. A. SAGATDINOVA, and T. KH DALAEVA. "Role of insulin resistance in predicting premature placental abruption." Practical medicine 22, no. 6 (2024): 68–73. https://doi.org/10.32000/2072-1757-2024-6-68-73.

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Premature detachment of a normally located placenta is an extremely severe complication of pregnancy, which is characterized by suddenness and peracute development, and the consequences of this condition can sometimes be irreparable. Placental abruption is one of the major obstetric syndromes, along with preeclampsia and fetal growth retardation, the pathogenesis of which is based on the so-called ischemic placental disease. Placentation disorders are associated with endothelial dysfunction, and insulin resistance is a morphological substrate of this pathology, along with other predictors. It
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2

Ramya Satya Pavani Devi, Yenugudhati, and Vaddadi Adi Lakshmi. "INCIDENCE, RISK FACTORS AND FETOMATERNAL OUTCOME IN ABRUPTIO PLACENTA." International Journal of Advanced Research 11, no. 02 (2023): 1163–66. http://dx.doi.org/10.21474/ijar01/16360.

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Abruptio placenta is defined as placental detachment before and during delivery.It remains a major cause of maternal and perinatal morbidity and mortality in developing countries.Over 50% of all perinatal deaths attributed to abruptio placenta are accompanied by premature delivery.In addition it accounts for 20-25% of antepartum hemorrhage,increased risk of DIC,maternal shock ,renal failure,PPH,and maternal death.This study aimed to determine the incidence ,risk factors and fetomaternal outcome in abruptio placenta.
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3

Borodynia, V. I., та O. A. Svyatchenko. "Передчасне відшарування плаценти коней (діагностика, лікування)". Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 82 (2017): 16–20. http://dx.doi.org/10.15421/nvlvet8204.

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In case of a premature placenta abruption, diagnostics should be done quickly, because it affects survival and viability of a foal. Premature detachment of the placenta in the mares, which occurs before or during birth, is not a common parable. This pathological condition ranges from 5 to 10% of all cases of abortion, the birth of dead fetuses and perinatal mortality in horses. The general condition of a mare usually is without any abnormalities. Clinical obstetric examination includes vaginal and sonographic study. When conducting a vaginal examination, it is possible to see an open cervix an
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4

Zainulina, Marina S. "On the pathogenetic mechanisms of premature detachment of the normally located placenta." Journal of obstetrics and women's diseases 53, no. 4 (2004): 19–25. http://dx.doi.org/10.17816/jowd88614.

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The aim of this study was to study the systemic and regional mechanisms of endothelial dysfunction and thrombophilia in the pathogenesis of premature detachment of the normally located placenta.
 To fulfill the assigned tasks, 340 women were examined. The main group included 72 women with premature detachment of the normally located placenta. The comparison groups consisted of 81 pregnant women in the III trimester of physiological pregnancy and 187 pregnant women in the III trimester with preeclampsia of varying severity.
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5

Gorikov, I. N., L. G. Nakhamchen, A. N. Odireev, et al. "Morphological changes in the bloodstream and chorionic villi in partial premature detachment of normally located placenta in women with exacerbation of herpesvirus and cytomegalovirus infection." Bulletin Physiology and Pathology of Respiration, no. 88 (July 4, 2023): 86–95. http://dx.doi.org/10.36604/1998-5029-2023-88-86-95.

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Aim. To assess the morphological changes in the bloodstream and chorionic villi with partial premature detachment of a normally located placenta in women with exacerbation of herpesvirus (HSV type 1) and cytomegalovirus infection (CMVI). Materials and methods. An X-ray phlebographic and histological examination of 87 placentas was carried out in uncomplicated pregnancy and partial premature detachment of a normally located placenta, developed after reactivation of HSV type 1 and CMVI in patients in the second trimester of gestation. The first group included 32 placentas from women with CMV-ser
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6

Guseva, Elena M. "BLEEDINGS IN THE HIGH-RISK GROUP OBSTETRIC HOSPITAL." V.F.Snegirev Archives of Obstetrics and Gynecology 5, no. 1 (2018): 37–40. http://dx.doi.org/10.18821/2313-8726-2018-5-1-37-40.

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Massive hemorrhage and hemorrhagic shock as main causes of deaths in pregnancy, occupy up to 25% in the structure of mortality rate in obstetrics. In the past decade, the decline in the share of deaths of mothers has occurred due to postpartum bleedings and bleedings in detachment or placenta previa. The aim of the study was to determine the frequency and structure of massive bleedings in a high-risk group obstetric hospital. Methods. A retrospective descriptive cohort study was executed in 2 stages: at the 1st stage - a study of 396 deliveries histories with main nosological forms leading to
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7

Chhabadia, Dr Gazal, Dr Harshali Mehandarkar, and Dr Neha Sharma. "Acute Kidney Injury Secondary to Abruptio Placenta: A Case Series Highlighting Maternal Complications." IOSR Journal of Dental and Medical Sciences 24, no. 6 (2025): 19–22. https://doi.org/10.9790/0853-2406071922.

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Abruptio placenta, also referred to as placental abruption, constitutes a significant obstetric emergency characterized by the premature detachment of the placenta from the uterine wall, frequently resulting in both the mother and the fetus morbidity and mortality . This condition is associated with various complications including disseminated intravascular coagulation, hypovolemic shock, and multi-organ dysfunction. Among these complications, acute kidney injury (AKI) induced by abruptio placenta is a rare yet life-threatening condition that necessitates prompt recognition and intervention. T
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8

Golyanovskiy, O. V., I. V. Klyuzko, K. V. Kulikovska, et al. "Placenta bipartita/bilobata in singleton pregnancy: risk of complications (case report)." Reproductive health of woman, no. 4 (June 30, 2025): 116–21. https://doi.org/10.30841/2708-8731.4.2025.335439.

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Placenta bipartita/bilobata (PB) in singleton pregnancy is a rare special variant of placentation, in which instead of one placental lobe, two placental lobes of approximately equal size are formed. The prevalence of this pathology is 2–8%, but the frequency of prenatally diagnosed PB is approximately 2% with a high frequency of complications during pregnancy and childbirth (premature birth, fetal distress, premature placental abruption, postpartum hemorrhage), which increases the frequency of cesarean section (CS).The objective: to present a rare, prenatally diagnosed case of placentation – P
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9

В., С. Ольшевський, and В. Ольшевська О. "OPERATIVE DELIVERY IN WOMEN WITH BENIGN UTERINE TUMORS." REPRODUCTIVE ENDOCRINOLOGY, no. 48 (August 29, 2019): 68–76. https://doi.org/10.18370/2309-4117.2019.48.68-76.

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Objective of the study: to determine the role of operative delivery in the childbirth tactics for women with benign uterine tumors based on the identification of pathogenetically substantiated criteria for operative birth, to prevent obstetric and perinatal complications. Materials and methods. In 110 women with uterine leiomyoma (LM) – 77 (70.0%) with one node (Group 1) and 33 (30.0%) with multiple nodes (Group 2) delivery tactics were defined. For this purpose, the type of LM, the location of the nodes relative to the placenta, complications of pregnancy, childbirth were revealed and a
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10

Zharkin, N. A., E. M. Lavenyukova, and A. E. Miroshnikov. "Premature detachment of normally situated placenta. Epidemiology, risk factors, prognosis, outcomes." Rossiiskii vestnik akushera-ginekologa 18, no. 3 (2018): 20. http://dx.doi.org/10.17116/rosakush201818320-24.

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11

Dodkhoeva, Munavvara, and Zumrat Salimova. "PREMATURE PLACENTAL ABRUPTION: EPIDEMIOLOGY, RISK FACTORS, AND MEDICAL AND SOCIOECONOMIC ASPECTS." AVICENNA BULLETIN 26, no. 4 (2024): 556–66. https://doi.org/10.25005/2074-0581-2024-26-4-556-566.

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Objective: To study epidemiology, risk factors, and medical and socioeconomic aspects of premature placental abruption (PPA) of a normally located placenta in the settings of a level III maternity care hospital. Methods: An analysis was conducted on 183 antenatal and delivery records of the women admitted to Maternity Hospital № 1 in Dushanbe, Republic of Tajikistan (RT), between 2019 and 2023. Among the women diagnosed with PPA, there were 19 cases of complete PPA and 164 cases of partial PPA. Results: The study has highlighted a growing trend in the incidence of PPA among pregnant women. How
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12

Romanenko, T. G., та O. M. Sulimenko. "Великі акушерські синдроми – сучасні можливості профілактики". HEALTH OF WOMAN, № 6(132) (30 липня 2018): 67–72. http://dx.doi.org/10.15574/hw.2018.132.67.

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The objective: was to reduce the incidence and severity of the development of «Great Obstetrical Syndromes»: miscarriage of pregnancy, placental insufficiency, fetal growth retardation and / or fetal distress, preeclampsia, premature detachment of a normally located placenta, premature delivery, by developing an algorithm for prophylaxis during pregnancy in women at high risk for their development. Materials and methods. Clinical and statistical analysis of pregnancy in 88 pregnant women with high risk of decompensation of placental insufficiency was conducted. Depending on the method of preve
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13

Aleksandrov, Maksim, Pavel Kuznetsov, and Alexander Slyotov. "Case of severe coagulopathy in a pregnant woman with total placental abruption." Hirurg (Surgeon), no. 5-6 (June 1, 2020): 70–77. http://dx.doi.org/10.33920/med-15-2003-05.

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The article describes case of successful treatment of severe coagulopathy, which developed as a result of total premature detachment of a normally located placenta. Medications and technologies used in the diagnosis and treatment of the patient are indicated. Reasonability of participating of an interdisciplinary team including obstetrician-gynecologists, resuscitation anesthetists, hematologists and vascular surgeons in the treatment of patients with massive blood loss has been confirmed.
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14

Kolenko, О. V., А. А. Fil, and Е. L. Sorokin. "Bilateral exudative retinal detachment formed against the background of severe preeclampsia." Modern technologies in ophtalmology, no. 1 (March 25, 2022): 183–87. http://dx.doi.org/10.25276/2312-4911-2022-1-183-187.

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Purpose. To present a clinical case of bilateral exudative retinal detachment in a patient with severe preeclampsia. Material and methods. Patient M. 19 years old. Pregnancy 27−28 weeks (III trimester), severe preeclampsia, premature detachment of a normally located placenta. Result. On examination, the pronounced edema of the eyelids and pale chemosis of the conjunctiva attracted attention. Visual acuity was extremely low and amounted to 0.01. Ophthalmoscopy in the upper quadrant of the right eye revealed a high vesicular retinal detachment with the capture of the macular region. In the left
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15

Kolenko, О. V., А. А. Fil, and Е. L. Sorokin. "Bilateral exudative retinal detachment formed against the background of severe preeclampsia." Modern technologies in ophtalmology, no. 1 (March 25, 2022): 183–87. http://dx.doi.org/10.25276/2312-4911-2022-1-183-187.

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Purpose. To present a clinical case of bilateral exudative retinal detachment in a patient with severe preeclampsia. Material and methods. Patient M. 19 years old. Pregnancy 27−28 weeks (III trimester), severe preeclampsia, premature detachment of a normally located placenta. Result. On examination, the pronounced edema of the eyelids and pale chemosis of the conjunctiva attracted attention. Visual acuity was extremely low and amounted to 0.01. Ophthalmoscopy in the upper quadrant of the right eye revealed a high vesicular retinal detachment with the capture of the macular region. In the left
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16

Barbosa, Cecilia Gomes, César Gómez-Hernández, Marcos Vinícius da Silva, et al. "Congenital transmission of Mexican strains of Trypanosoma cruzi TcIa: interaction between parasite and human placental explants." Parasitology 149, no. 3 (2021): 418–26. http://dx.doi.org/10.1017/s0031182021002018.

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AbstractCongenital transmission of Chagas disease plays an important role in endemic countries because it is not a diagnosis that is encountered frequently in prenatal care. Due to limited information regarding congenital transmission of Trypanosoma cruzi in Mexico, the present study aimed to investigate protozoan infectivity and modulation of immune responses in human placental explants infected with T. cruzi Ia Mexican strains. The Inc-5 strain showed increased infectivity and modulated IL-1β, IL-10 and TLR-4, decreasing their expression after 24 h of infection. Both strains (Inc-5 and Ninoa
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17

Kadyrova, A. F., K. B. Puzakov, Andrey V. Murashko, T. A. Seredina, and I. V. Gadaeva. "MODERN METHODS OF VISUALIZATION OF PATHOLOGICAL PLACENTATION." V.F.Snegirev Archives of Obstetrics and Gynecology 4, no. 4 (2017): 178–80. http://dx.doi.org/10.18821/2313-8726-2017-4-4-178-180.

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The deterioration of the attachment of the placenta is associated with an increased risk of the development of its premature detachment, postpartum hemorrhages, intrauterine and intranatal fetal death. The fused placenta occurs approximately in 9% of women with placenta previa and in 0.004% of women without placenta previa. The timely made diagnosis of this pathologyis critically important for choosing the amount of surgical intervention for delivery, which is always associated with increased blood loss. This review examines issues of the diagnosis of placenta attachment. Data on advantages an
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18

Pasman, N. M., and O. V. Chumanova. "The role of thrombophilia in the premature detachment of a normally located placenta." Obstetrics, Gynecology and Reproduction 13, no. 1 (2019): 29–34. http://dx.doi.org/10.17749/2313-7347.2019.13.1.029-034.

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19

Anokhova, L. I., T. E. Belokrinitskaya, Yu N. Smolyakov, and A. V. Pateyuk. "THE MODEL OF FORECASTING PREMATURE DETACHMENT OF NORMALLY LOCATED PLACENTA AT INCOMPLETE PREGNANCY." Siberian Medical Review, no. 3 (2018): 80–87. http://dx.doi.org/10.20333/2500136-2018-3-80-87.

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20

Batrak, Galina A., and Nataliya V. Batrak. "Course of pregnancy and labor in women with type 2 diabetes mellitus and obesity." Clinical review for general practice 5, no. 9 (2024): 57–61. http://dx.doi.org/10.47407/kr2024.5.9.00479.

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Maternal diabetes is associated with pregnancy complications and increased rates of adverse maternal and neonatal outcomes. Short-term complications include macrosomia, large for gestational age, respiratory distress syndrome, neonatal hypoglycemia, neonatal intensive care unit admission, fetal growth restriction, congenital anomalies, preterm birth, preeclampsia, operative delivery, while in the long term both mothers and their infants have an increased risk of metabolic diseases. The results of the conducted scientific study confirm that type 2 diabetes and obesity are closely associated wit
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21

Guilherme, Henrique Ros, Fernandes Queiroga Frederico, Rocha Ferreira Gabriel, et al. "EMERGÊNCIA OBSTÉTRICA: DESCOLAMENTO PREMATURO DA PLACENTA E RISCOS À GESTANTE E O FETO." Revistaft 27, no. 120 (2023): 12. https://doi.org/10.5281/zenodo.7760012.

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<strong>Introdu&ccedil;&atilde;o:&nbsp;</strong>&Agrave;s emerg&ecirc;ncias obst&eacute;tricas s&atilde;o uma problem&aacute;tica de sa&uacute;de p&uacute;blica que requer aten&ccedil;&atilde;o por parte dos &oacute;rg&atilde;os majorit&aacute;rios. Uma das mais recorrentes &eacute; o descolamento prematuro de placenta, a qual eleva o risco de morbimortalidade para o bin&ocirc;mio (m&atilde;e-feto).&nbsp;<strong>Objetivo:&nbsp;</strong>Identificar o estado da arte acerca dos riscos &agrave; gestante e ao feto provocados pelo descolamento prematuro da placenta.&nbsp;<strong>M&eacute;todos:&nbsp
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22

Lyoshenko, Irina, Oleg Tarabrin, Maxim Holubenko, and Dmitry Havrichenko. "The use of inhibitors of fibrinolysis in the treatment of obstetric hemorrhage due to placenta detachment." Journal of Education, Health and Sport 6, no. 1 (2016): 129–37. https://doi.org/10.5281/zenodo.44836.

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&nbsp; <strong>Lyoshenko I. A., Tarabrin O. A., Holubenko M. Yu., Havrichenko D. H. The use of inhibitors of fibrinolysis in the treatment of obstetric hemorrhage due to placenta detachment. </strong><strong>Journal of Education, Health and Sport. </strong><strong>2016;6(1):129-137. eISSN 2391-8306. DOI</strong> <strong>http://dx.doi.org/10.5281/zenodo.44836</strong> <strong>http://ojs.ukw.edu.pl/index.php/johs/article/view/44836</strong> <strong>https://pbn.nauka.gov.pl/works/696071</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <strong>The journal has had 7 points in Ministry of Science and Hig
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23

Nikitin, D. A., V. S. Verbitski, L. N. Vasileva, et al. "COVID 19 INFECTION AS A RISK FACTOR FOR PREMATURE DETACHMENT OF THE NORMALLY LOCATED PLACENTA." Medical Journal, no. 3(77) (2021): 77–81. http://dx.doi.org/10.51922/1818-426x.2021.3.77.

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A retrospective analysis of childbirth was carried out in 298 women with confirmed COVID-19 infection (main group) who received treatment in the maternity hospital of the 6th City Clinical Hospital of Minsk in the period from April 14, 2020 to February 14, 2021. The control group included pregnant women who gave birth during 2017—2019 in this medical institution (total 12 812). There was an increase in the incidence of premature birth from 2.7 % in pregnant women in the control group to 5.7 % in patients with COVID-19. The pathology in pregnancy significantly increased the frequency of cesarea
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24

Baeder, Fernando Martins, Daniel Furtado Silva, Paola Fernanda Leal Corazza, et al. "Efeitos deletérios ocasionados por sonda orogástrica em recém nascido a pré-termo em uma uti neonatal: relato de caso clínico." Research, Society and Development 9, no. 12 (2020): e41191211385. http://dx.doi.org/10.33448/rsd-v9i12.11385.

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There are countless causes that lead a baby to be born premature: placental changes (placenta previa and premature detachment), excess amniotic fluid, maternal age (mothers under 18 years of age), maternal infections, primacy, use of alcohol and drugs. The premature baby's trajectory begins with hospitalization, usually for long periods in the Neonatal Intensive Care Unit (NICU), due to pulmonary immaturity and the need for prolonged ventilatory support. Gastric probing by oral or nasal route is an essential procedure in assisting nutrition for newborns up to thirty-four weeks of gestational a
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25

Makatsaria, Alexander Davidovich, Svetlana Vladimirovna Akinshina, Viktoriya Omarovna Bitsadze, and Margarita Darchievna Andreeva. "Severe obstetric complications as a manifestation of thrombotic microangiopathy." Journal of obstetrics and women's diseases 64, no. 5 (2015): 6–15. http://dx.doi.org/10.17816/jowd6456-15.

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Thrombotic microangiopathy is one of the most serious thrombotic complications characterized by microvascular thrombosis in various organs and accompanied by thrombocytopenia and hemolytic anemia. The term thrombotic microangiopathy has incorporated several nosology, which are characterized by different mechanisms of microvascular thrombosis. Currently thrombotic microangiopathy include thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), heparin-induced thrombocytopenia, HELLP-syndrome. Pregnancy presents one of the key triggers to the development of thrombotic microang
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26

Novakovic, Predrag, Susan E. Detmer, Muhammad Suleman, Carol M. Malgarin, Daniel J. MacPhee, and John C. S. Harding. "Histologic Changes Associated With Placental Separation in Gilts Infected with Porcine Reproductive and Respiratory Syndrome Virus." Veterinary Pathology 55, no. 4 (2018): 521–30. http://dx.doi.org/10.1177/0300985818765067.

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The placenta is a vital organ providing the developing fetus with nutrient and gas exchange, thermoregulation, and waste elimination necessary for fetal development, as well as producing hormones to maintain pregnancy. It is hypothesized that fetal pig death in porcine reproductive and respiratory syndrome may be attributed to pathology of the maternal-fetal interface leading to premature placental separation. This study was designed to evaluate the chronologic progression of porcine reproductive and respiratory syndrome virus (PRRSV)–induced lesions at the maternal-fetal interface, with parti
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27

Zabolotnov, V. A., O. O. Khvatova, and Y. P. Sehedina. "Thrombophilia and obstetric complications." HEALTH OF WOMAN, no. 2(138) (March 30, 2019): 56–60. http://dx.doi.org/10.15574/hw.2019.138.56.

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This article discusses the relationship of thrombophilia with obstetric complications. In women with habitual miscarriage, do not perform screening for hereditary thrombophilia. With habitual miscarriage, women should undergo screening before pregnancy to detect antiphospholipid antibodies. Positive screening results are an indication for the appointment of LMWH and aspirin. Women with IVF do not investigate for hereditary thrombophilia and do not do LMWH therapy. Do not perform an assessment of congenital thrombophilia in women with miscarriage, with a history of childbirth with FGR, pre-ecla
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28

Bagiyants, V. A., N. M. Milyaeva, A. V. Kulikov, and V. V. Kovalev. "Coagulation Tests and Volume of Blood Loss in Patients with Premature Placental Abruption." Ural Medical Journal 23, no. 1 (2024): 4–11. http://dx.doi.org/10.52420/2071-5943-2024-23-1-4-11.

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Introduction. Placental abruption continues to be one of the leading causes of bleeding during pregnancy and delivery, posing a direct threat to the health and life of both mother and fetus, making a significant contribution to the structure of maternal and neonatal morbidity and mortality. The study of predictors and prediction of the severity of the consequences of this complication is one of the areas of scientific research.The purpose of the study is to expand the possibilities of predicting massive bleeding, which is a consequence of premature placental abruption, based on the analysis of
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Andreeva, Margarita Darchoevna. "Clinical value of determination of markers of a thrombophylia at patients with the complicated pregnancy in the anamnesis." Journal of obstetrics and women's diseases 64, no. 2 (2015): 13–17. http://dx.doi.org/10.17816/jowd64213-17.

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The results of the survey of 214 patients with the complicated pregnancy (a preeclampsia, a premature detachment of placenta, antenatal fetal death, miscarriage) in the anamnesis are presented in the article. We determined the level of molecular markers of a thrombophilia (TAT, D-dimer) and aggregation activity of platelets and carried out antithrombotic therapy to these women. It is shown that 47,7 % of such nonpregnant women and pregnant early terms have the high level of D-dimer, TAT - 46,7 %, aggregation activity of platelets - 52,6 %. Determination of the increased levels of molecular mar
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30

Васильковская, Е. Н., А. Э. Каспарова, С. А. Медведева, and Э. М. Ганбарова. "THE ROLE OF A PERINATAL CENTER IN A MULTIDISCIPLINARY HOSPITAL IN THE PREVENTION OF MATERNAL MORTALITY CAUSED BY OBSTETRIC BLEEDING: THEN AND NOW." Vestnik SurGU. Meditsina 17, no. 2 (2024): 51–59. http://dx.doi.org/10.35266/2949-3447-2024-2-7.

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The study aims to evaluate the role of a perinatal center in a multidisciplinary hospital in the prevention of maternal mortality caused by obstetric bleeding. The study used the continuous sampling method to conduct a retrospective analysis of 185 cases of pregnancies and their outcomes in women with obstetric bleeding during pregnancy, labor, and the postpartum period treated at the Perinatal Center in Khanty-Masiysk from 2010 to 2011 and from 2019 to 2020. It was identified that primary risk factors for maternal mortality due to obstetric bleeding include iron deficiency anemia; gestational
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31

Pecheriaha, S., and I. Marynchyna. "Prevention of pregnancy complications and delivery at low placentation." Bukovinian Medical Herald 25, no. 3 (99) (2021): 83–88. http://dx.doi.org/10.24061/2413-0737.xxv.3.99.2021.13.

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Objective is to evaluate the effectiveness of the developed method of preventing pregnancy complications with low placentation from early gestation.Material and methods. We have examined 119 pregnant women with low placentation. This diagnosis was made at 6-7 weeks of gestation on the basis of echographic research. The main group consisted of 64 pregnant women with low chorionic location who underwent prevention from pregnancy complications in early gestation by the complex of medicines developed by us and a control group -55 women with low placentation who had not undergone complications prop
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32

Белоцерковцева, Л. Д., Л. В. Коваленко, В. В. Панкратов, et al. "SARS-COV-2 IS A NEW RISK FACTOR FOR PREECLAMPSIA." Vestnik SurGU. Meditsina 16, no. 2 (2023): 26–33. http://dx.doi.org/10.35266/2304-9448-2023-2-26-33.

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The study aims to assess the risks for preeclampsia progression in pregnant women with SARS-CoV-2 based on the study obtained in 2021, which included the pregnancy course and outcome of 1 122 women divided into three groups. The groups were as following: 52 pregnant women with positive SARS-CoV-2 and preeclampsia, 302 women with negative SARS-CoV-2 and preeclampsia, and 768 pregnant women with positive SARS-CoV-2 and without preeclampsia. Chronic arterial hypertension prevailed in women with positive SARS-CoV-2 and preeclampsia by 2.5 times in comparison with those with negative SARS-CoV-2 and
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Roman, A. Bontsevich Olga V. Severinova Natalia A. Chukhareva Tatiana S. Filinichenko Anna A. Gavrilova. "THE SUCCESSFUL CLINICAL CASE OF A SEVERE ARTERIAL HYPERTENSION MANAGEMENT DURING PRECONCEPTION AND PREGNANCY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 10396–400. https://doi.org/10.5281/zenodo.1467395.

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<em>A timely diagnosis and rational management of arterial hypertension (AH) in pregnancy are of the great importance among the practicing doctors. According to the World Health Organization (WHO), different types of hypertension in pregnancy took the 2<sup>nd</sup> place in maternal mortality structure in 2014 causing at least 76 thousand of maternal and 500 thousand of fetal deaths annually [3, 11]. Over the past decade, the 4<sup>th</sup> place of mortality rate in fetus is caused by hypertension and its complications. The maximum rate of fetal mortality was indicated at women 35 years of a
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Komilova, Mastura Safarovna, and Zhanna Evgenievna Pakhomova. "ENDOTHELIAL DYSFUNCTION AND CYTOKINES: A ROLE IN THE DEVELOPMENT OF PREMATURE DEPARTMENT OF A NORMALLY LOCATED PLACENTA." Journal of reproductive health and uro-nephrology research 3, no. 4 (2022): 5. https://doi.org/10.5281/zenodo.7418824.

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For the normal development and functioning of the placenta, it is important to have a balance between various mechanisms of angiogenesis, as well as a balance between the processes of angiogenesis and apoptosis, which is maintained by the ratio of proangiogenic and antiangiogenic factors secreted by both the endothelial cells themselves and the cells of the microenvironment. Changes in the balance of cytokines and vascular growth factors in the microenvironment of endothelial cells underlie pathological disorders of placentation, gestation at different stages of pregnancy, and preterm birth. &
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35

Cristina, Vasiliu, Cojocaru Lorena, Malusanu Patricia, Albu Elena Simona, and Cîrstoiu Monica. "MAJOR OBSTETRICAL COMPLICATIONS IN AN ELDERLY PRIMIPAROUS WITH A MULTITUDE OF PRE-EXISTING PATHOLOGIES." Romanian Journal of Emergency Surgery 2, no. 1 (2020): 44–49. http://dx.doi.org/10.33695/rojes.v2i1.24.

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The number of primiparous pregnant women, over the age of 35, has increased considerably in the past few years, because of the elevated level of education and also because the multitude of contraceptive methods. Such a patient suits the category of elderly primiparous and it represents a real obstetrical challenge, due to the numerous complications related to pregnancy and the immediate postpartum, as well as those related to the neonatal prognosis. We present a 35 old years patient, second gestation, primiparous, a partially monitored pregnancy, known with essential hypertension grade III ESC
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36

Chereshnev, V. A., S. V. Pichugova, L. G. Tulakina, et al. "Ultrastructure of placenta in antenatal fetal death." Obstetrics, Gynecology and Reproduction 12, no. 3 (2018): 36–46. http://dx.doi.org/10.17749/2313-7347.2018.12.3.036-046.

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The current obstetrical protocols and the improved perinatal services have led to a significant decrease in the intrapartum and neonatal mortality; however, the rate of antenatal fetal death remains high. In a search for a mechanism of this abnormality, we conducted a comprehensive morphological study of the placental ultrastructure in women with antenatal fetal death. Aim: to determine the ultrastructural characteristics of the placenta in these women. Materials and methods. We analyzed 60 cases of antenatal fetal death and conducted an electron microscopic study of placental terminal chorion
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Eremeeva, D. R., and M. S. Zainulina. "Assessing the effectiveness of preventing placenta-associated complications in patients with burdened obstetric history and circulating antiphospholipid antibodies." Obstetrics, Gynecology and Reproduction 18, no. 4 (2024): 475–91. http://dx.doi.org/10.17749/2313-7347/ob.gyn.rep.2024.479.

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Introduction. The role of antiphospholipid antibody (APA) carriage in the pathogenesis of pregnancy failure is one of the most recently debated issues. To date, no unified therapeutic approach to immunotherapy of antiphospholipid syndrome (APS) in pregnancy exists. Intravenous immunoglobulins (IVIG) have become the drugs of choice to treat this pathology in pregnant women.Aim: to evaluate an effectiveness of preventing placenta-associated complications (PACs) in patients with recurrent miscarriage and circulating APAs.Materials and Methods. A prospective study was conducted to analyze the cour
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Мamontova, I. K., T. V. Shevlyakovа, and E. I. Petrova. "Analysis of obstetric «near miss» cases in the Ryazan region." Obstetrics, Gynecology and Reproduction 12, no. 4 (2019): 30–36. http://dx.doi.org/10.17749/2313-7347.2018.12.4.030-036.

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Although maternal mortality cases in Russia have become rare, the problem of their prevention remains relevant. To enforce the preventive measures, an analysis of critical conditions and «near miss» cases in obstetrics is commonly used. As a result, the quality of medical care in obstetric institutions improves. Aim: to assess the character and incidence of critical situations in obstetrics practice over the Ryazan region in 2015-2017 and to analyze the failures in medical care that led to such situations. Materials and methods. We analyzed 46 «near miss» cases and 1 case of maternal death rec
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Batrak, G. A., N. V. Batrak, and M. V. Zhaburina. "Type 2 diabetes mellitus: course and outcomes of pregnancy on the example of a clinical case." Meditsinskiy sovet = Medical Council, no. 23 (January 22, 2025): 118–22. https://doi.org/10.21518/ms2024-549.

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In recent years, the study of the course and outcomes of pregnancy in the presence of type 2 diabetes mellitus (DM) has attracted more attention from researchers. Type 2 diabetes mellitus most often develops in adults, but in recent years it has often occurred in young women planning a pregnancy. Type 2 DM in the mother is associated with pregnancy complications and an increase in adverse outcomes for both the woman and the newborn. Short-term complications include macrosomia, respiratory distress syndrome, neonatal hypoglycemia, congenital fetal malformations, and in the long term, both the m
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40

Amor, M. B., O. P. Gnatko, and N. G. Skuriatina. "OBSTETRIC AND PERINATAL OUTCOMES IN PREGNANCY WITH DIFFERENT SEVERITY AND TIME OF THE MANIFESTATION OF PREECLAMPSIA." Актуальні питання педіатрії, акушерства та гінекології, no. 2 (November 8, 2018): 110–13. http://dx.doi.org/10.11603/24116-4944.2018.2.9572.

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The aim of the study – to conduct a retrospective analysis of the course of pregnancy and delivery to determine the nature of obstetric and perinatal complications in preeclampsia.&#x0D; Materials and Methods. The analysis was based on the results of the evaluation of the medical documentation (individual medical records of the pregnant woman, birth histories, developmental histories of the newborn) in 224 pregnant women with preeclampsia and 80 pregnant women without preeclampsia. In addition to the results of the clinical and laboratory examination, the analysis included the severity of pree
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Mikhaylin, Evgeny S., Lada A. Ivanova, Mariya M. Shilo, and Igor V. Berlev. "Pregnancy and childbirth with Shereshevsky–Turner syndrome, established at 12 years of age." Gynecology 22, no. 6 (2020): 90–92. http://dx.doi.org/10.26442/20795696.2020.6.200407.

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The article presents a personal observation of the course of pregnancy and childbirth in a patient with a typical form of gonadal dysgenesis (ShereshevskyTurner syndrome, karyotype 45,X0/46,XY in the ratio of clones 1:1). The diagnosis was established at 12 years of age during an examination for growth retardation and lack of signs of puberty. Given the presence of a 46,XY clone in the karyotype, a high risk of malignization of dysgenetic gonads, laparoscopy and gonadectomy were performed at 12 years of age. Pregnancy occurred after preparation of the endometrium with estrogens and progestogen
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Можейко, Л. Ф., Т. В. Марковская, Р. Л. Коршикова, О. В. Дядичкина, Э. В. Федотова, and С. М. Стасевич. "The Uterus Couvelaire: the Possibility of Preserving the Reproductive Organ (Clinical Case)." Репродуктивное здоровье. Восточная Европа, no. 4 (November 4, 2020): 518–24. http://dx.doi.org/10.34883/pi.2020.10.4.014.

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В настоящей работе представлен клинический случай преждевременной отслойки нормально расположенной плаценты, осложненной антенатальной гибелью плода и развитием матки Кувелера в сроке гестации 232 дня. Данная патология возникла у беременной женщины с отягощенным акушерским анамнезом из группы материнского риска по инфицированию, невынашиванию, развитию фетоплацентарной недостаточности, преэклампсии, тромбоэмболическим осложнениям. Оптимальная утеротоническая, гемотрансфузионная и гемостатическая терапия с использованием современных оперативных методик позволила сохранить репродуктивный орган и
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43

Grigoryan, Narinе V., Sergey P. Sinchikhin, and Lusine V. Stepanyan. "Clinical cases of childbirth in 13-year-old adolescents." V.F.Snegirev Archives of Obstetrics and Gynecology 10, no. 3 (2023): 235–38. http://dx.doi.org/10.17816/2313-8726-2023-10-3-235-238.

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In the literature, limited articles have been found regarding childbirth in minors, with the majority of young women giving birth falling between ages of 15 and 18. Therefore, the authors found it noteworthy to present two clinical cases of childbirth in 13-year-old adolescents. Both girls come from single-parent families, are not enrolled in education or employment, and had unwanted pregnancies. They did not receive prenatal care from a gynecologist or register at an antenatal clinic. During their pregnancies, both girls experienced various diseases and complications. This article highlights
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44

Lemish, N. Y. "The course of pregnancy and childbirth in women with preeclampsia." UKRAINIAN JOURNAL HEALTH OF WOMAN, no. 1(164) (March 15, 2023): 39–44. http://dx.doi.org/10.15574/hw.2023.164.39.

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Purpose - to determine the features of pregnancy and childbirth in women who had complications from the group of major obstetric syndromes (MOS), which were clinically manifested by pre-eclampsia. Materials and methods. A retrospective clinical and statistical analysis of the course of pregnancy and childbirth in 103 pregnant women with pre-eclampsia (main group - MG) was performed. The control group (CG) included 56 practically healthy pregnant women with a favorable reproductive history and uncomplicated pregnancy. Statistical processing of the study results was performed using standard soft
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45

Rudenko, Kseniia A., Nikita R. Ryabokon, Victor A. Bart, and Irina E. Zazerskaya. "The features of preeclampsia and the fetal condition during pregnancy complicated by COVID-19." Journal of obstetrics and women's diseases 74, no. 1 (2025): 56–66. https://doi.org/10.17816/jowd636515.

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BACKGROUND: COVID-19 continues to be relevant for such a vulnerable population as pregnant women. An increased risk of adverse perinatal outcomes such as hypertensive disorders of pregnancy, fetal distress, and intrauterine fetal death has been reported, but the published data remain contradictory and confusing. Of particular interest is the association between COVID-19 and preeclampsia due to the proposed common pathogenetic mechanisms. AIM: The aim of this study was to assess the clinical manifestations of preeclampsia in patients with previous coronavirus disease and the impact of COVID-19
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46

Zolotukhin, K. N., I. B. Fatkullina, A. Yu Lazareva, et al. "Experience of extracorporeal membrane oxygenation in a laboring woman with severe preeclampsia." Ural Medical Journal 21, no. 5 (2022): 88–93. http://dx.doi.org/10.52420/2071-5943-2022-21-5-88-93.

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Introduction. Hypertensive disorders during pregnancy are one of the main causes of maternal mortality in the world. Both premature detachment of the normally located placenta, which led to massive bleeding on the background of placental insufficiency, according to the theory of placental ischemia, and disruption of compensatory mechanisms, leading to multiple organ failure, can lead to an unfavorable outcome. The pathogenesis of lung damage in preeclampsia is based on the activation of lipid peroxidation. Therefore, one of the components of complex therapy of severe lung damage may be the use
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47

Milyaeva, N. M., V. V. Kovalev, A. V. Kulikov, and V. A. Bagiyants. "Progressive detachment of the normally located placenta: the clinical case of failed maternal death in massive blood loss." Ural Medical Journal 22, no. 1 (2023): 78–84. http://dx.doi.org/10.52420/2071-5943-2023-22-1-78-84.

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Introduction. Despite the global achievements of obstetric science and practice, massive bleeding with premature progressive detachment of the normally located placenta, as well as in placenta previa and ingrowth, hypotonic bleeding, occupy one of the leading positions in the structure of obstetric bleeding and are associated with high rates of nearly dead women (near miss), with maternal and perinatal morbidity and mortality. The purpose of the study was to demonstrate the effectiveness of organizational methodology of emergency care in a 24-hour hospital using the clinical example of PPCR wi
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Pachuliia, Olga V., Maria S. Dolgikh, Tatiana S. Zhernakova, and Olesya N. Bespalova. "Epigenetic mechanisms of fetal programming in excessive intake of synthetic folates at the preconception stage." Journal of obstetrics and women's diseases 72, no. 4 (2023): 93–104. http://dx.doi.org/10.17816/jowd115052.

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To date, there is no doubt that taking folic acid at the perigravid stage in an adequate dosage has a positive effect on fetal development and the course and outcome of pregnancy. There is extensive evidence that during pregnancy, folate deficiency is associated with spontaneous miscarriages, premature birth, and premature detachment of the normally positioned placenta, and it can cause intrauterine malformations of the nervous and cardiovascular systems of the fetus.&#x0D; Understanding the need to reduce such severe complications, which have both medical and social significance, has contribu
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Atfi, F., I. El Abbassi M. Jalal, A. Lamrissi, K. Fichtali, and S. Bouhya Maternity El Harouchi Casablanca. "ATYPICALPRESENTATION OF PREECLAMPSIA. ABOUT A CASE." International Journal of Advanced Research 10, no. 01 (2022): 35–38. http://dx.doi.org/10.21474/ijar01/14008.

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3 to 5% of pregnancies are complicated by pre-eclampsia, which remains one of the main causes of fetal-maternal mortality and morbidity worldwide. The rate is higher in Morocco where the lack of prenatal consultation explains why pre-eclampsia is diagnosed at advanced stages. It is also responsible for 10 to 15% of maternal deaths in the Western world, and it remains the second leading cause of maternal death in France after the hemorrhage during delivery. Severe early pre-eclampsia (before 32 weeks of pregnancy) is associated with a risk of maternal mortality 20 times higher than after 37 wee
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Ратникова, С. Ю., Т. П. Жукова, Е. С. Зайцева, and Т. Г. Конева. "Genetic factors of predisposition to hereditary forms of thrombophilia in women with high-risk pregnancy." Nauchno-prakticheskii zhurnal «Medicinskaia genetika», no. 11(220) (November 30, 2020): 87–88. http://dx.doi.org/10.25557/2073-7998.2020.11.87-88.

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В настоящее время огромное значение имеет оценка генетических факторов, приводящих к риску тромбоэмболических осложнений у беременных женщин. Проведено исследование полиморфизма генов системы гемостаза (F5 (G1691А), F2 (G20210A), SERPINC1(G786A), PROC(A2583T)) методом полимеразной цепной реакции в режиме реального времени у 63 пациенток с отягощенным акушерским анамнезом. Показано, что присутствие в генотипе у 48 пациенток (76%) одного или сочетания нескольких низкофункциональных аллелей исследуемых генов является фактором риска развития тромбофилических осложнений беременности (фетоплацентарн
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