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Journal articles on the topic 'Premature ejaculation'

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Published: 4 June 2021
Last updated: 11 March 2023

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1

Waldinger, Marcel D. "Premature Ejaculation." Drugs 67, no. 4 (2007): 547–68. http://dx.doi.org/10.2165/00003495-200767040-00005.

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2

Giuliano, Fran??ois. "Premature Ejaculation." Drugs 67, no. 11 (2007): 1629–30. http://dx.doi.org/10.2165/00003495-200767110-00006.

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3

McMahon, ChrisG. "Premature ejaculation." Indian Journal of Urology 23, no. 2 (2007): 97. http://dx.doi.org/10.4103/0970-1591.32056.

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4

Broderick, Gregory A. "Premature Ejaculation." Journal of Sexual Medicine 3 (September 2006): 293–94. http://dx.doi.org/10.1111/j.1743-6109.2006.00312.x.

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5

SKOLNIK, NEIL, and CHRISTOPHER NOTTE. "Premature Ejaculation." Family Practice News 35, no. 6 (March 2005): 63. http://dx.doi.org/10.1016/s0300-7073(05)70203-6.

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6

Shenassa, Ben, and Wayne Hellstrom. "PREMATURE EJACULATION." Southern Medical Journal 92, Supplement (November 1999): S93. http://dx.doi.org/10.1097/00007611-199911001-00233.

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7

Andersen, Monica Levy, and Sergio Tufik. "Premature ejaculation – Dopaminergic control of ejaculation." Drug Discovery Today: Therapeutic Strategies 2, no. 1 (March 2005): 41–46. http://dx.doi.org/10.1016/j.ddstr.2005.05.009.

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8

Generali, Joyce, and Dennis J. Cada. "Tramadol: Premature Ejaculation." Hospital Pharmacy 41, no. 11 (November 2006): 1048–50. http://dx.doi.org/10.1310/hpj4111-1048.

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9

Francischi, Fábio Barros de, Daniel Cernach Ayres, Ricardo Eidi Itao, Luis Cesar Fava Spessoto, Jose Germano Ferraz del Arruda, and Fernando Nestor Facio Junior. "Premature ejaculation: is there an efficient therapy?" Einstein (São Paulo) 9, no. 4 (December 2011): 545–49. http://dx.doi.org/10.1590/s1679-45082011rb1929.

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ABSTRACT Premature ejaculation is the most frequent male sexual dysfunction, estimated to affect 20 to 30% of men at some time in their life. A Pubmed search from the year 2000 to the present was performed to retrieve publications related to management or treatment of premature ejaculation. Behavioral techniques have been the mainstay of premature ejaculation management for many years, although evidence of their short-term efficacy is limited. Topical therapies for premature ejaculation act by desensitizing the penis and do not alter the sensation of ejaculation. Selective serotonin reuptake inhibitors (SSRIs), commonly used in the treatment of depression, are often used to treat premature ejaculation, based on the observation that delayed ejaculation is a frequent side effect of this drug class. Dapoxetine is a short-acting SSRI formulated to treat premature ejaculation, and results seem very promising.
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10

Sajdlova, R., and L. Fiala. "Premature ejaculation and stress." European Psychiatry 65, S1 (June 2022): S282. http://dx.doi.org/10.1192/j.eurpsy.2022.723.

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Introduction Recent findings indicate that men with premature ejaculation report more frequent sexual problems associated with increased anxiety and interpersonal difficulties. Also the neuroendocrine changes were examined and compared to other indicators of stressful experiences. Objectives Premature Ejaculation (PE) is defined as an ejaculation occurring within one minute after the start of sexual intercourse and occurs in 20-30% of men. They report frequent problems with partnerships and increased anxiety, irritability and orgasmic dysfunction. Premature ejaculation is likely to be associated with decreased serotonergic neurotransmission and higher levels of leptin. Also the role of hyperactive thyroid and prostate disease was investigated. On the other hand there is no evidence as to how previous stressful experience and distrubed partnership might contribute PE. Methods Our study comprised 60 male outpatients diagnosed as having secondary premature ejaculation. Clinical examinations were focused on biochemical analysis of cortisol and psychometric scoring using a diagnostic tool for premature ejaculation, traumatic stress and somatoform dissociation. The control group consisted of a 60 healthy men. Results The results showed significant Spearman correlations of the Premature Ejaculation Diagnostic Tool score with Trauma symptoms checklist score (R=0.86), cortisol level (R=0.47) and Somatoform dissociation questionnaire score (R=0.61). In the control group, the results did not reach statistical significance. Spearman correlations of the Premature Ejaculation Diagnostic Tool score with Trauma symptoms checklist score was (R=0.21), cortisol (R=0.27) and with Somatoform dissociation questionnaire score (R=0.25). Conclusions These results represent the first reported findings documenting the relationship of traumatic stress indicators with the experience of secondary premature ejaculation and cortisol levels. Disclosure No significant relationships.
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11

Abdel-Meguid, Taha A., Ahmed J. Alsayyad, Abdulmalik M. Tayib, Hasan M. Farsi, Hisham A. Mosli, Moataz Sait, and Ahmed Abdelsalam. "Can Intraprostatic Injection of OnabotulinumtoxinA be Benefi cial to Treat Premature Ejaculation? Results of a Prospective Study." Journal of King Abdulaziz University - Medical Sciences 24, no. 4 (December 31, 2017): 1–7. http://dx.doi.org/10.4197/med.24-4.1.

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We prospectively evaluated efficacy and adverse effects of intraprostatic injections of onabotulinumtoxinA to treat premature ejaculation. Twenty-four men ≥19 years-old with premature ejaculation for ≥ 6 months and intravaginal ejaculation latency time ≤ 2 minutes underwent transurethral intraprostatic injections of onabotulinumtoxinA (100 U). Primary endpoint was change of intravaginal ejaculation latency time at 3-months. Secondary endpoints included changes in premature ejaculation profile and patient-reported global impression of change (PGI). Mean baseline ejaculation latency time has significantly increased at 1-, 3- and 6-months, respectively. In premature ejaculation profile “perceived control over ejaculation”, significant improvement was reported at 3-months, while non-significant changes were reported at 1- and 6-months. Patients reported non-significant changes of “personal distress related to ejaculation” and “interpersonal difficulty related to ejaculation”. Only 8.3%, 12.5% and 12.5% of men reported “better” at 1-, 3- and 6-months, respectively, while all other patients reported “no change” or “slightly better” in patient-reported global impression of change. No serious adverse effects were observed. Improvements of intravaginal ejaculation latency time were not clinically meaningful, as most men reported “no change” or “slightly better” in patient-reported global impression of change. These marginal improvements did not support using onabotulinumtoxinA intraprostatic injections to remedy premature ejaculation.
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12

Piediferro, G., A. Russo, A. Crimi, and G. Luciano. "Ejaculation Disorders: Our Experience." Urologia Journal 64, no. 3 (June 1997): 301–6. http://dx.doi.org/10.1177/039156039706400304.

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Over a 12-year period the authors have studied 132 patients with premature primitive ejaculation treated with metoclopramide, fluoxetine and/or sexual techniques and kinesitherapy. Best and lasting results were achieved with an association of serotonergic drug (fluoxetine) with sexual and kinesitherapy (84.62%). Fifty-two patients with hemospermia were studied and 63.5% were found to have an infection of the urogenital tract, idiopathic in 15%. The proportion and persistence of hemospermia in some cases would not suggest that this be considered a minor andrological symptom. The authors have also studied 82 painful ejaculations, 6 retrograde ejaculations and 8 anejaculations.
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13

Riley, Alan. "Premature ejaculation and pharmacotherapy." International Journal of Pharmaceutical Medicine 14, no. 6 (2000): 309–10. http://dx.doi.org/10.2165/00124363-200012000-00002.

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14

Gajjala, SukumarReddy, and Azheel Khalidi. "Premature ejaculation: A review." Indian Journal of Sexually Transmitted Diseases and AIDS 35, no. 2 (2014): 92. http://dx.doi.org/10.4103/0253-7184.142391.

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15

Aglan, A. "Premature ejaculation surgical treatment." Journal of Sexual Medicine 19, no. 5 (May 2022): S166—S167. http://dx.doi.org/10.1016/j.jsxm.2022.03.380.

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16

Piediferro, G., A. Russo, A. Orimi, and G. Luciano. "Premature Ejaculation: Our Experience." Urologia Journal 63, no. 2 (April 1996): 254–57. http://dx.doi.org/10.1177/039156039606300220.

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Over a 10-year period the Authors have studied 103 patients with premature primitive ejaculation treated with Metoclopramide, Fluoxetine and/or sexual techniques (squeeze, stop and start, positional techniques). Best results were achievied with an association of Fluoxetine and sexual therapy (77.33%). Fluoxetine (serotonergic) seems to be more effective than Metoclopramide (antidopaminergic).
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17

Riley, A., and R. T. Segraves. "Treatment of premature ejaculation." International Journal of Clinical Practice 60, no. 6 (May 24, 2006): 694–97. http://dx.doi.org/10.1111/j.1368-5031.2006.00818.x.

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18

Safarinejad, M., and S. Hosseini. "Pharmacotherapy for Premature Ejaculation." Current Drug Therapy 1, no. 1 (January 1, 2006): 37–46. http://dx.doi.org/10.2174/157488506775268434.

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19

McMahon, Chris G. "Management of premature ejaculation." Human Andrology 2, no. 4 (December 2012): 79–93. http://dx.doi.org/10.1097/01.xha.0000415235.79085.e6.

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20

Jannini, Emmanuele A., Mario Maggi, and Andrea Lenzi. "Evaluation of Premature Ejaculation." Journal of Sexual Medicine 8 (October 2011): 328–34. http://dx.doi.org/10.1111/j.1743-6109.2011.02289.x.

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21

Buvat, Jacques. "Pathophysiology of Premature Ejaculation." Journal of Sexual Medicine 8 (October 2011): 316–27. http://dx.doi.org/10.1111/j.1743-6109.2011.02384.x.

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22

Jannini, Emmanuele A., and Andrea Lenzi. "Epidemiology of premature ejaculation." Current Opinion in Urology 15, no. 6 (November 2005): 399–403. http://dx.doi.org/10.1097/01.mou.0000182327.79572.fd.

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23

Waldinger, Marcel D. "Pharmacotherapy for premature ejaculation." Current Opinion in Psychiatry 27, no. 6 (November 2014): 400–405. http://dx.doi.org/10.1097/yco.0000000000000096.

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24

Waldinger, Marcel D. "Pharmacotherapy for premature ejaculation." Expert Opinion on Pharmacotherapy 16, no. 17 (November 18, 2015): 2615–24. http://dx.doi.org/10.1517/14656566.2015.1096928.

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25

Palmer, Neil R. "Tramadol for Premature Ejaculation." Journal of Sexual Medicine 6, no. 1 (January 2009): 299. http://dx.doi.org/10.1111/j.1743-6109.2008.00916.x.

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26

Zhao, Qi, Hengheng Dai, Xihao Gong, Lu Wang, Minran Cao, Haisong Li, and Bin Wang. "Acupuncture for premature ejaculation." Medicine 97, no. 35 (August 2018): e11980. http://dx.doi.org/10.1097/md.0000000000011980.

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27

Feige, A. M., M. R. Pinsky, and W. J. G. Hellstrom. "Dapoxetine for Premature Ejaculation." Clinical Pharmacology & Therapeutics 89, no. 1 (November 17, 2010): 125–28. http://dx.doi.org/10.1038/clpt.2010.215.

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28

Haensel, Stefan, Taco Klem, Wim C. J. Hop, and A. Koos Slob. "Fluoxetine and Premature Ejaculation." Journal of Clinical Psychopharmacology 18, no. 1 (February 1998): 72–77. http://dx.doi.org/10.1097/00004714-199802000-00012.

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29

Renshaw, Domeena C. "Premature Ejaculation Revisited—2005." Family Journal 13, no. 2 (April 2005): 150–52. http://dx.doi.org/10.1177/1066480704273873.

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30

Kravos, M. "Bupropion-Associated Premature Ejaculation." Pharmacopsychiatry 43, no. 04 (March 22, 2010): 156–57. http://dx.doi.org/10.1055/s-0030-1249034.

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31

Hsu, Yu-Chao, Hsin-Chieh Huang, and Shih-Tsung Huang. "Treatment of premature ejaculation." Urological Science 24, no. 1 (March 2013): 2–6. http://dx.doi.org/10.1016/j.urols.2013.01.004.

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32

McCarty, E. J., and W. W. Dinsmore. "Premature ejaculation: treatment update." International Journal of STD & AIDS 21, no. 2 (February 2010): 77–81. http://dx.doi.org/10.1258/ijsa.2009.009434.

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33

Brewer, Gayle, and Paul Tidy. "Premature ejaculation: therapist perspectives." Sexual and Relationship Therapy 32, no. 1 (May 26, 2016): 22–35. http://dx.doi.org/10.1080/14681994.2016.1188200.

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34

McMahon, Chris G. "Dapoxetine for premature ejaculation." Expert Opinion on Pharmacotherapy 11, no. 10 (June 14, 2010): 1741–52. http://dx.doi.org/10.1517/14656566.2010.493174.

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35

Russo, Giorgio Ivan, and Ege Can Serefoglu. "Premature Ejaculation: 2020 Update." Current Sexual Health Reports 11, no. 4 (November 7, 2019): 411–20. http://dx.doi.org/10.1007/s11930-019-00232-9.

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36

Mirkin, Ya B., D. A. Cherepanov, A. N. Nevsky, and P. S. Kyzlasov. "Selective cryoablacion of penile nerves as a treatment for premature ejaculation." Experimental and Сlinical Urology 15, no. 4 (December 25, 2022): 102–6. http://dx.doi.org/10.29188/2222-8543-2022-15-4-102-106.

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Introduction. Premature ejaculation (PE) is the second most common male sexual dysfunction with a significant negative impact on quality of life. To date, there is no satisfactory treatment for PE. Surgical methods of treatment are based on reducing the sensitivity of the glans penis by various methods, the main of which is selective dorsal neurotomy (SDN). Recently, methods have been developed for temporary demyelination of the dorsal nerve of the penis using cryoablation. This article discusses the results of selective minimally invasive cryoablation for the treatment of PE. as a treatment for premature ejaculation. Materials and methods. Materials and methods. The methods of SDN by the criablation method are described. The study involved 29 patients aged 22 to 35 years (mean age 28.7 years). All patients met the Criteria for Premature Ejaculation. Patients filled out the Premature Ejaculation Profile and recorded the time of Intravaginal Ejaculation Latency Time (IELT) before and after 3 months after SDN by cryoablation. Results. After the operation average IELT increased from of 75.8 seconds to 227.6 seconds (+298%), the average Premature Ejaculation Profile score increased from 3.6 to 11.35 points (+315%). Conclusions. Selective minimally invasive cryoablation of penile nerves is a promising treatment for premature ejaculation. However, additional studies with a larger number of participants are needed.
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37

Moreland, Amanda J., and Eugene H. Makela. "Selective Serotonin-Reuptake Inhibitors in the Treatment of Premature Ejaculation." Annals of Pharmacotherapy 39, no. 7-8 (July 2005): 1296–301. http://dx.doi.org/10.1345/aph.1e069.

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OBJECTIVE To review the use of selective serotonin-reuptake inhibitors (SSRIs) in the treatment of premature ejaculation. DATA SOURCES Articles were retrieved through a MEDLINE search (1966–January 2004). Search terms used to identify articles included serotonin uptake inhibitors, premature ejaculation, rapid ejaculation, and sexual behavior, as well as the generic names of currently available SSRIs: fluoxetine, fluvoxamine, paroxetine, sertraline, citalopram, and escitalopram. The literature search was limited to articles published in the English language containing human subjects. STUDY SELECTION AND DATA EXTRACTION Articles obtained through the literature search were evaluated, and randomized controlled trials were included in this review. Information from noncontrolled trials or case reports was considered for inclusion if it contributed to the completeness of this review and if it was the highest level of evidence available. DATA SYNTHESIS Premature ejaculation is a commonly reported sexual difficulty. Delayed ejaculation is a widely reported sexual adverse effect of SSRIs. In some men exhibiting premature ejaculation, the ability of the SSRIs to delay ejaculation has been therapeutic. Trials evaluating the ejaculation-delaying ability of SSRIs demonstrated that paroxetine, fluoxetine, sertraline, and citalopram produce a statistically significant increase in the ejaculation latency time compared with placebo. CONCLUSIONS Taking advantage of the ejaculation-delaying effects of SSRIs increases the treatment options available to prescribers and patients. Convenience and minimal adverse effect profile make these agents an alternative to previously used behavior modalities and older pharmacologic agents. Although some questions still surround the details of their use, SSRIs have the potential to improve the quality of life for men with premature ejaculation and their partners.
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38

Donatucci, Craig F. "Etiology of Ejaculation and Pathophysiology of Premature Ejaculation." Journal of Sexual Medicine 3 (September 2006): 303–8. http://dx.doi.org/10.1111/j.1743-6109.2006.00305.x.

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39

Ventus, D., A. Gunst, and P. Jern. "Physical Exercise is Negatively Correlated with Premature Ejaculation Symptom Severity." Klinička psihologija 9, no. 1 (June 13, 2016): 59. http://dx.doi.org/10.21465/2016-kp-op-0036.

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Objective: To examine associations between symptoms of premature ejaculation and erectile dysfunction and the lifestyle factors alcohol use and physical exercise. Design and Method: An invitation to an online survey was sent out to a population-based sample of Finnish twins and siblings of twins in 2012. Of the 2559 individuals invited, 1054 responded, giving a response rate of 41%. Individuals who used SSRI-medication for any reason were excluded, leaving a final sample of 843. Premature ejaculation was measured by the validated Multiple Indicators of Premature Ejaculation questionnaire, erectile dysfunction by the International Index of Erectile Function – 5, alcohol use by the Alcohol Use Disorders Identification Test, and physical exercise by the Godin Leisure-Time Exercise Questionnaire. Bivariate correlations were used to test associations between variables. Results: There was a significant negative correlation between physical exercise and premature ejaculation symptoms. Premature ejaculation and erectile dysfunction were significantly positively correlated. Effect sizes were moderately small. No significant correlations were found between the other variables. Conclusions: Our results indicate that physical exercise may possibly prevent or counteract premature ejaculation. Future studies could incorporate physical exercise in treatment trials.
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40

Yepes, Salome Agudelo, Jenniffer Puerta Suárez, Alejandro Carvajal, and Walter D. Cardona Maya. "Prostatitis and premature ejaculation: two enemies of masculinity." Journal of Medical Research 6, no. 5 (October 28, 2020): 255–61. http://dx.doi.org/10.31254/jmr.2020.6518.

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Prostatitis and premature ejaculation are urological problems that impact sexual and reproductive health in males frequently. The aim of this narrative review is to provide an overview of the relationship between premature ejaculation and prostatitis. A narrative review literature was performed in the PubMed and SCOPUS databases. The most relevant aspects of the etiology of premature ejaculation were detailed, and the causal relationship between prostatitis and premature ejaculation was explored. Treatment should consider the pathophysiology and diagnosis; this is a significant challenge for the urologist. A total of 45 original articles were compiled in a table within the main findings. Both alterations are associated with a decrease in the quality of life and have a negative impact on the couple's relationship. The timely treatment offers improvement or complete recovery for the patients.
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41

St. Lawrence, Janet S., and Sudhakar Madakasira. "Evaluation and Treatment of Premature Ejaculation: A Critical Review." International Journal of Psychiatry in Medicine 22, no. 1 (March 1992): 77–97. http://dx.doi.org/10.2190/uwp1-cnhh-l0nk-yqy9.

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Objective: Premature ejaculation is the most prevalent male sexual dysfunction. The present article is a comprehensive review of the literature on premature ejaculation. Method: This critical discussion of the literature evaluates the definitional issues, theoretical conceptualizations, assessment strategies, and treatment alternatives for premature ejaculation. Results: The review integrates the most recent findings on the diagnosis and treatment of premature ejaculation updating an earlier review with the addition of more than fifty recent articles and adding sections on treatment generalization and maintenance, medical evaluation, pharmacological intervention, and a discussion of methodological issues in the literature. Conclusions: The pause-squeeze technique remains the current treatment of choice for the disorder. However, this unitary treatment recommendation disguises a multidimensional disorder which has yet to evolve an operational definition, psychometrically sound assessment procedures, or clearly articulated etiology.
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42

Althof, Stanley E. "Prevalence, Characteristics and Implications of Premature Ejaculation/Rapid Ejaculation." Journal of Urology 175, no. 3 (March 2006): 842–48. http://dx.doi.org/10.1016/s0022-5347(05)00341-1.

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43

Soni, Kiran, Han-Seong Jeong, and Sujeong Jang. "Neurons for Ejaculation and Factors Affecting Ejaculation." Biology 11, no. 5 (April 29, 2022): 686. http://dx.doi.org/10.3390/biology11050686.

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Ejaculation is a reflex and the last stage of intercourse in male mammals. It consists of two coordinated phases, emission and expulsion. The emission phase consists of secretions from the vas deferens, seminal vesicle, prostate, and Cowper’s gland. Once these contents reach the posterior urethra, movement of the contents becomes inevitable, followed by the expulsion phase. The urogenital organs are synchronized during this complete event. The L3–L4 (lumbar) segment, the spinal cord region responsible for ejaculation, nerve cell bodies, also called lumbar spinothalamic (LSt) cells, which are denoted as spinal ejaculation generators or lumbar spinothalamic cells [Lst]. Lst cells activation causes ejaculation. These Lst cells coordinate with [autonomic] parasympathetic and sympathetic assistance in ejaculation. The presence of a spinal ejaculatory generator has recently been confirmed in humans. Different types of ejaculatory dysfunction in humans include premature ejaculation (PE), retrograde ejaculation (RE), delayed ejaculation (DE), and anejaculation (AE). The most common form of ejaculatory dysfunction studied is premature ejaculation. The least common forms of ejaculation studied are delayed ejaculation and anejaculation. Despite the confirmation of Lst in humans, there is insufficient research on animals mimicking human ejaculatory dysfunction.
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44

Roblin, David. "Premature ejaculation: diagnosis and pharmacotherapy." International Journal of Pharmaceutical Medicine 14, no. 6 (2000): 313–18. http://dx.doi.org/10.2165/00124363-200012000-00008.

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45

&NA;. "Escitalopram effective in premature ejaculation." Inpharma Weekly &NA;, no. 1613 (November 2007): 17. http://dx.doi.org/10.2165/00128413-200716130-00030.

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46

Saitz, Theodore Robert, and Ege Can Serefoglu. "The epidemiology of premature ejaculation." Translational Andrology and Urology 5, no. 4 (August 2016): 409–15. http://dx.doi.org/10.21037/tau.2016.05.11.

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47

Althof, Stanley E. "Psychosexual therapy for premature ejaculation." Translational Andrology and Urology 5, no. 4 (August 2016): 475–81. http://dx.doi.org/10.21037/tau.2016.05.15.

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48

Palmer, Neil R., and Bronwyn G. A. Stuckey. "Premature ejaculation: a clinical update." Medical Journal of Australia 188, no. 11 (June 2008): 662–66. http://dx.doi.org/10.5694/j.1326-5377.2008.tb01827.x.

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49

Dignam, Paul T. "Premature ejaculation: a clinical update." Medical Journal of Australia 189, no. 6 (September 2008): 351–52. http://dx.doi.org/10.5694/j.1326-5377.2008.tb02073.x.

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50

Palmer, Neil R., and Bronwyn G. A. Stuckey. "Premature ejaculation: a clinical update." Medical Journal of Australia 189, no. 6 (September 2008): 351–52. http://dx.doi.org/10.5694/j.1326-5377.2008.tb02074.x.

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