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Journal articles on the topic 'Premature rupture of membranes (PROM)'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Sefik Gokce and Dilsad Herkiloglu. "Premature rupture of membranes." World Journal of Advanced Research and Reviews 11, no. 3 (2021): 363–70. http://dx.doi.org/10.30574/wjarr.2021.11.3.0393.

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Prenatal (premature) rupture of membranes (PROM) is defined as rupture of fetal membranes before the onset of labor or regular uterine contractions. PROM can lead to serious complications such as uterine cavity infection, umbilical cord compression, oligohydramnios, fetal malpresentation, umbilical cord prolapse, preterm delivery, fetal asphyxia and death. Initial evaluation of all term pregnancies with suspected PROM should include confirmation of membrane rupture and assessment of maternal and fetal well-being. Immediate initiation of labor is recommended in term pregnant women with PROM. Co

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Sefik, Gokce, and Herkiloglu Dilsad. "Premature rupture of membranes." World Journal of Advanced Research and Reviews 11, no. 3 (2021): 363–70. https://doi.org/10.5281/zenodo.5560279.

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Prenatal (premature) rupture of membranes (PROM) is defined as rupture of fetal membranes before the onset of labor or regular uterine contractions. PROM can lead to serious complications such as uterine cavity infection, umbilical cord compression, oligohydramnios, fetal malpresentation, umbilical cord prolapse, preterm delivery, fetal asphyxia and death. Initial evaluation of all term pregnancies with suspected PROM should include confirmation of membrane rupture and assessment of maternal and fetal well-being. Immediate initiation of labor is recommended in term pregnant women with PROM. Co

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Gultom, Abitmer, Carissa Wijaya, and Jumaini Andriana Sihombing. "Outcome of Elderly Pregnancy Complicated with Anaemia and PROM." Journal of Advances in Medicine and Medical Research 37, no. 6 (2025): 9–17. https://doi.org/10.9734/jammr/2025/v37i65847.

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Introduction: Premature rupture of membranes (PROM) is defined as the amniotic sac rupture before labor occurs. If PROM occurs at 37 weeks of gestation or more, it is called term PROM or premature rupture of membranes (PROM); conversely, if it occurs before 37 weeks of gestation, it is called preterm PROM or preterm premature rupture of membranes (PPROM). The problem of PROM requires greater attention, because its prevalence is large and tends to increase. Aim: Reporting a case of premature rupture of membranes > 12 hours in a 24-year-old female patient. Case Detail: Case of a 24-year-old f

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Azam, Azmeena, Hafiz Maoz Husnain, and Iqra Marryum. "PREMATURE RUPTURE OF MEMBRANES." Professional Medical Journal 25, no. 02 (2018): 168–72. http://dx.doi.org/10.29309/tpmj/2018.25.02.433.

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Background: Pre-labour rupture of the membranes is one of the most commonclinical presentations in an obstetric setting. Early diagnosis is a major challenge faced byevery obstetrician and key to effective management and prevention of complications. As aresult of PROM, amniotic fluid that provides protection to the developing fetus is lost, exposingit to the outside environment. β-hCG is a hormone secreted by syncytiotrophoblasts found inamniotic fluid that can be studied for the evaluation of PROM. Objectives: To find the DiagnosticAccuracy of β human chorionic gonadotrophin test in vaginal w

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Banotra, Palvi, Zahoor Ahmad, and Samaa Haneef. "Fetal-Maternal Complications due to Premature Rupture of Membranes: A Prospective Study at Valley’s Famous Maternity Hospital." International Journal of Research and Review 9, no. 1 (2022): 610–13. http://dx.doi.org/10.52403/ijrr.20220170.

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Background: The fetal membrane remains intact till the labor starts in order to maintain the protective intrauterine fluid environment. However, sometimes membranes ruptures prematurely (PROM), a condition in which the disruption of fetal membranes takes place before the beginning of labor that ultimately results in spontaneous leakage of amniotic fluid. The present study is aimed to evaluate the feto-maternal outcomes due to premature rupture of membranes at term. Methods: A total 70 pregnant women patients with premature rupture of membranes after 37 completed weeks were selected in the stud

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Azqinar, Tiara Cornela, and Agung Ikhssani. "The Role of Vitamin C in the Prevention of Premature Rupture of Membranes." Journal of Maternal and Child Health Sciences (JMCHS) 1, no. 2 (2021): 51–56. http://dx.doi.org/10.36086/maternalandchild.v1i2.966.

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Premature rupture of membranes [PROM] is an early event in approximately one third of preterm births resulting in significant infant mortality and morbidity. The exact mechanism by which the fetal membranes weaken and rupture in term and preterm pregnancy is unknown. However, it has been hypothesized that the fetal membranes weaken and eventually rupture as a result of collagen remodeling and apoptosis. Some studies have speculated that vitamin C supplementation during pregnancy will be useful in the prevention of PROM but some studies have also shown that vitamin C supplementation does not af

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Charan Murmu, Mangal, Ratikanta Mahala, Jyoti Ranjan Champatiray, and Madhusmita Pradhan. "Outcome of neonates born to mothers with premature rupture of membranes." Panacea Journal of Medical Sciences 11, no. 2 (2021): 197–203. http://dx.doi.org/10.18231/j.pjms.2021.043.

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Premature rupture of membranes (PROM) is a syndrome characterized by rupture of the fetal membranes before labour. Acute chorioamnionitis complicates 0.5% - 10% of all pregnancies but the incidence may be as high as 3-25% in pregnancies complicated by PROM of more than 24 hours duration. Intrauterine infection specially chorioamnionitis is one of the most serious problems found by the practicing Obstetrician and subsequently by the Pediatrician. The incidence of neonatal infection for infants born to women with PROM range from 1 – 2.6%. To know the incidence, clinical course, outcome of early

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Rahayu, Budi. "HUBUNGAN FAKTOR-FAKTOR USIA IBU, PARITAS, UMUR KEHAMILAN, DAN OVER DISTENSI DENGAN KEJADIAN KETUBAN PECAH DINI DI RUMAH SAKIT YOGYAKARTA." MEDIA ILMU KESEHATAN 7, no. 2 (2019): 137–42. http://dx.doi.org/10.30989/mik.v7i2.233.

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Background: Premature rupture of membranes (PROM)is a rupture of membranes before any signs of labor and awaited before the labor occurs. The problem of PROM is a major obstetric issue, because the impact of PROM is an infection in the maternal and ends in an increased incidence of cesarean section due to a failed normal childbirth and neonatal. Factors that causePROMitself is not known for certain, but if we know earlier about the predisposing factors of PROM preventive efforts will be more helpful and reduce maternal and neonatal morbidity and mortality. Objective: Relationship of mate

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Rahayu, Budi. "HUBUNGAN FAKTOR-FAKTOR USIA IBU, PARITAS, UMUR KEHAMILAN, DAN OVER DISTENSI DENGAN KEJADIAN KETUBAN PECAH DINI DI RUMAH SAKIT YOGYAKARTA." Media Ilmu Kesehatan 7, no. 2 (2018): 137–42. http://dx.doi.org/10.30989/mik.v7i2.282.

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Background: Premature rupture of membranes (PROM)is a rupture of membranes before any signs of labor and awaited before the labor occurs. The problem of PROM is a major obstetric issue, because the impact of PROM is an infection in the maternal and ends in an increased incidence of cesarean section due to a failed normal childbirth and neonatal. Factors that causePROMitself is not known for certain, but if we know earlier about the predisposing factors of PROM preventive efforts will be more helpful and reduce maternal and neonatal morbidity and mortality.Objective: Relationship of maternal ag

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Serudji, Joserizal, and Erkadius Erkadius. "KEEFEKTIFAN MISOPROSTOL PERORAL SEBAGAI PEMATANGAN SERVIKS PADA KETUBAN PECAH DINI KEHAMILAN ATERM DENGAN SKOR BISHOP ≤ 4 DI PADANG." JOURNAL OBGIN EMAS 2, no. 2 (2019): 87–91. http://dx.doi.org/10.25077/aoj.2.2.87-91.2018.

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Premature rupture of membranes (PROM) is defined as rupture of membranes before contraction (his). PROM is the case of 5-10% of all deliveries. 70% of cases of PROM occur in term pregnancies. So that PROM in aterm pregnancies is suggested to induce labor to reduce the incidence risk of mother and fetus complications. This study aimed to compare the effectiveness of cervical ripening by using Misoprostol 25 µg peroral and without using Misoprostol 25 µg at term premature rupture of the membrane with Bishop Score ≤ 4. This study was conducted at the Departement of Obstetrics and Gynecology, Dr.

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Puji Astuti, Dwi Lestari, Ni Wayan Ariyani, and Ni Made Dwi Mahayati, SST. "Prevalence and Factors Associated with Premature Rupture of Membranes in Denpasar Bali." International Journal of Science and Healthcare Research 7, no. 4 (2022): 7–12. http://dx.doi.org/10.52403/ijshr.20221002.

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Premature rupture of membranes (PROM) is an obstetric problem which is one of the factors causing prematurity, infection, malpresentation, umbilical cord prolapse and perinatal mortality. This study aims to identify the relationship between sociodemographic and obstetric factors with the premature rupture of membranes in women giving birth. This cross-sectional study involved 274 people from 859 deliveries from January to December 2020, at a referral hospital in Denpasar, Bali. The sampling technique used is simple random sampling. The process of collecting data was taken from medical records

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Purnamawati, Intan. "Risk factor for premature rupture of membranes: a clinical study." International Journal of Research in Medical Sciences 12, no. 5 (2024): 1462–65. http://dx.doi.org/10.18203/2320-6012.ijrms20241228.

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Background: Premature rupture of membranes (PROM) is the rupture of the amniotic membrane before the onset of labour. Based on the time of occurrence, PROM can be divided into two, namely Premature Rupture of Membranes (PROM) and Preterm Premature Rupture of Membranes (PPROM). PROM occurs at or after 37 weeks gestation. PPROM, occurs before 37 weeks gestation. Methods: This study is a descriptive retrospective analytical observational study with cross sectional method. This research uses SPSS data processing. Data were taken from the medical records of inpatients in the maternity ward at Bima

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Rufaida, Zulfa. "Proporsi Asfiksia Neonatorum pada Kasus KPD dengan Non KPD di RSUD dr. Mohammad Soewandhi Surabaya." Jurnal Kebidanan Midwiferia 2, no. 1 (2016): 34–44. http://dx.doi.org/10.21070/mid.v2i1.762.

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Severe fetal or asphyxia intrauterin can be a result of cord compression and repetitive due to prolonged reduction prolapsus amniotic fluid or umbilical cord. Complications are most common in PROM before 37 weeks gestation is respiratory distress syndrome (asphyxia), which occurs in 10-40% of new born babies. Risk of infection, disability, and death was also increased in the PROM events. This research methods, analytical case control study design. Inpartu mother population in maternity hospitals VK dr. Mohamad Soewandhie Surabaya in 2008 some 2101 cases. Sampling techniques proportional strati

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Noviana, Ekki, Fauzul Munah, and Windy Oktaviasary. "The Correlation of Parity and Premature Rupture of Amnius." Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 11, no. 1 (2024): 062–67. http://dx.doi.org/10.26699/jnk.v11i1.art.p062-067.

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Premature Rupture of Membranes (PROM) is a condition where the amniotic membranes rupture before delivery. Under normal circumstances 8-10% of preterm pregnant women will experience PROM. One of the contributors to AKI is the incidence of infection where this infection is caused by PROM. Term pregnant women under normal circumstances 8 – 10% will experience PROM. Preterm PROM occurs in 1% of pregnancies. PROM is more common in multiparous and grand multiparas due to excessive uterine motility, reduced cervical flexibility. The aim of the research was to determine the correlation between parity

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Yulius, Will Hans, Aditiyono Aditiyono, Akhmad Yogi Pramatirta, and Siti Salima. "The Relationship between Maternal Characteristics and Neonatal Outcomes of Premature Rupture of Membranes." Indonesian Journal of Obstetrics & Gynecology Science 7, no. 3 (2024): 335. http://dx.doi.org/10.24198/obgynia.v7i3.682.

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Introduction: Premature rupture of the membranes occurs when the amniotic membrane bursts before 37 weeks of gestation. Preterm labour is the primary cause of perinatal and neonatal death, with premature membrane rupture accounting for 40% of cases. This study aimed to investigate the relationship between the incidence of premature rupture of membranes (PROM) with maternal characteristics and neonatal outcomes.Method: This study was carried out through medical record analysis in premature rupture of membrane patients at the Regional General Hospital Prof. Dr. Margono Soekarjo for the period Ju

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Gultom, Abitmer, Frisca Angreni, and Praisela Syania Hendrieta Nelwan. "Special Case Report of Pregnancy 28-30 Weeks Gestation with Premature Rupture of Membranes." Galore International Journal of Health Sciences and Research 9, no. 4 (2025): 79–83. https://doi.org/10.52403/gijhsr.20240407.

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Background: Premature rupture of membranes (PROM) can be defined as a rupture of the membranes before delivery that can occur at any gestational age. PROM can occur at gestational age before 37 weeks or after 37 weeks. The incidence of PROM ranges from 8-10% of all pregnancies. Management decisions depend on gestational age and evaluation of the relative risks of delivery versus the risks of expectant management when pregnancy is allowed to progress to a later gestational age. Case presentation: Patient with pregnancy at 28 – 30 weeks gestation. The patient came to the ER of General Hospital w

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Wulandari, Dwi Indah, Fara Khanza Azizah, Catur Setyorini, and Fajar Rana Rosyadah. "Karakteristik Ibu Bersalin dengan Ketuban Pecah Dini (KPD) di Puskesmas Manisrenggo Klaten." Journal of Applied Agriculture, Health, and Technology 3, no. 2 (2024): 9–13. https://doi.org/10.20961/jaht.v3i2.2161.

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Premature rupture of membranes (PROM) is usually defined as the amniotic sac before uterine contractions occur. In 2018, the incidence of PROM is recorded at around 5% to 10% of all labor cases. This study aimed to determine the characteristics of mothers giving birth with premature rupture of membranes (PROM) at the Manisrenggo Klaten Health Center in 2024. The research method was quantitative descriptive. The study population was all mothers who gave birth with PROM at the Manisrenggo Klaten Health Center. This study used secondary data from the KIA data. The sample in this study used a tota

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Ahmad Ridlo and Himatul Khoeroh. "Analisis Study Kasus Persalinan Patologis Pada Ny. J Umur 40 Tahun G4P2A1 Dengan Persalinan Spontan Atas Indikasi Ketuban Pecah Dini (KPD) Di RSUD Brebes." Jurnal Siti Rufaidah 2, no. 1 (2024): 34–45. http://dx.doi.org/10.57214/jasira.v2i1.57.

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Premature Rupture of Membranes (PROM) is a condition where the amniotic membranes rupture before signs of labor appear. Cases of premature rupture of membranes at Brebes District Hospital are cases that are often encountered; this case reached 273. The impact of PROM has a high risk to the continued health of the mother and fetus. The aim of this research is to analyze midwifery care comprehensively using Varney's 7 steps. This research uses a qualitative descriptive method with a case study approach. Data collection used interview methods, observation, physical examinations, supporting examin

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Magsi, Shahida, Sonia Gul Qureshi, Fatima Rajput, Basma Zia, and Inayatullah Magsi. "Frequency of Cesarean Section in Premature Rupture of Membranes." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 74–76. http://dx.doi.org/10.53350/pjmhs2216874.

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Background: Premature rupture of membranes (PROM) is always of clinical significance either it occurs before onset of labour at term or preterm. It is defined as spontaneous rupture of fetal membranes which results in leakage of amniotic fluid. PROM is related with maternal and perinatal morbidity and mortality if not treated sensibly on time, due not only to conditions causing it but also likelihood of emergency cesarean delivery. Aim: To ascertain frequency of C- section in women presented with premature rupture of membranes at tertiary care hospital. Study Design: Cross-sectional descriptiv

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Sancar, Muhyiddin, Esranur Atiç, Mehmet Uğur Karabat, Şehmus Kaplan, Ayfer Aktaş, and Fırat Aşır. "Investigation of Adhesion Molecules in the Placentas of Patients with Gestational Diabetes Mellitus with Premature Rupture of Membranes." Journal of Drug Delivery and Therapeutics 15, no. 2 (2025): 45–48. https://doi.org/10.22270/jddt.v15i2.7019.

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Aim: The aim of this study was to examine the histopathological changes in the placentas of patients with Gestational Diabetes Mellitus (GDM) and premature rupture of membranes (PROM). Materials and Methods: Placentas of 21 GDM+PROM and 21 healthy pregnant women were sectioned into 4-6 μm sections and stained with Hematoxylin-Eosin. Results: In GDM+PROM group, fibrinoid deposition in light pink areas, degeneration of chorionic villi and irregularities in villus structure, congestion and dilatation of capillary vessels were observed. Leukocyte infiltration was observed in the intervillous area.

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الكعكي, Nahla Saleh. "Prevalence of the pattern of Pre-labor premature rupture of membranes among pregnant women at Al-Sadaqa Teaching Hospital, Aden, Yemen." Journal of medical and pharmaceutical sciences 6, no. 5 (2022): 52–65. http://dx.doi.org/10.26389/ajsrp.h050122.

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Pre-labor rupture of membranes (PROM) is the rupture of membranes before the onset of labor. It is a common obstetric problem (3 -4%) in developed and developing countries. The aim of this study to describe the pattern of PROM in pregnancies at Al-Sadaqa Teaching Hospital, Aden, Yemen from January to February 2020. This is a descriptive hospital based study of the patients diagnosed as PROMs managed in the Obstetrics and Gynecology Department. In this study 151 pregnant women with PROM comprising 11.1% of 1360 total deliveries. Only 9 (0.7%) patients presented with preterm premature rupture of

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MN., Amulya, and Ashwini MS. "Maternal outcome in term premature rupture of membranes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 2 (2019): 576. http://dx.doi.org/10.18203/2320-1770.ijrcog20190287.

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Background: Rupture of Fetal membranes before the onset of labour is called PROM. Premature rupture of membrane (PROM) is associated with various complications. The present study is undertaken to study the maternal morbidity in term PROM.Methods: A prospective cross-sectional study was conducted at Vijaynagar institute of medical science Ballari for a period of one year by Department of Obstetrics and Gynecology from November 2016 to October 2017. 120 cases of spontaneous rupture of membranes with term gestation with confirmed PROM were selected.Results: PROM was common in age group of 20-29 y

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Yusuf, Abisowo Oshodi, Oyedeko MuyideenOladipo, TawaqualitAbimbolaOttun, Motunrayo Akinlusi Fatimat, and OnyinyechiChionuma Joy. "Maternal Demography and Neonatal Outcomes in Term Pre Labour Rupture of Membranes Versus Spontaneous Labour Preceding Ruptured Membranes in Lagos, Nigeria: A Comparative Study." International Journal of Innovative Science and Research Technology 8, no. 3 (2023): 1186–91. https://doi.org/10.5281/zenodo.7783889.

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Term prelabour rupture of membranescomplicates about 5% to 10% of term pregnancies and imposes therapeutic challenges upon the managing obstetrician. While spontaneous labour followed by ruptured membranes is the accepted default pathway towards delivery at term, comparative studies on term PROM and spontaneous onset of labour preceding ruptured membranes are scarce globally. Objective: To compare maternal socio-demography and neonatal outcomes of term PROM versus spontaneous onset of labour before membrane rupturein our tertiary facility. Methods: A prospective comparative study of 300 subjec

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Sudiarta, I. Ketut Edy, Monicha Zalzabilla Aldinasyah, Cindy Jennilyn Candra, Supriyono Supriyono та Annisa Ullya Rasyida. "High NF-κB and RAGE Expression in Fetal Membrane of Premature Rupture of Membrane (PROM) Subject". Indonesian Biomedical Journal 14, № 3 (2022): 289–93. http://dx.doi.org/10.18585/inabj.v14i3.1859.

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BACKGROUND: Premature Rupture of Membranes (PROM) is significantly linked to the infections-related maternal deaths. In the inflammatory process, the influencing stressor will stimulate the activation of Nuclear Factor Kappa B (NF-κB) and Receptor of Advanced Gyclation End product (RAGE). Yet up to date, the expression of NF-κB and RAGE in pregnant women with PROM are still rarely studied. Therefore, this study aimed to observe the differences of NF-κB and RAGE expression from PROM and non-PROM subjects.METHODS: This was a cross-sectional study involving 20 PROM subjects and 20 non-PROM subjec

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Surya Negara, Ketut, Ketut Suwiyoga, Komang Arijana, and Ketut Tunas. "Role of Apoptosis Inducing Factor (AIF) as Risk Factors of Premature Rupture of Membranes." Biomedical and Pharmacology Journal 11, no. 2 (2018): 719–24. http://dx.doi.org/10.13005/bpj/1425.

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Premature rupture of membrane (PROM) is an obstetric problem related to the prevalence, prematurity, morbidity and mortality of perinatal. The etiology of PROM is multifactorial and the mechanism remains unclear. The weakening of amniotic membrane is suspected due to various biochemistry process that causing remodeling and apoptosis, and the stretch of the amniotic membrane. Apoptosis plays an integrated role in the pathogenesis of PROM. The mechanism of apoptosis is through caspase-dependent and caspase-independent pathway. Apoptosis protein such as Apoptosis Inducing Factor (AIF) as caspase

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Ernita, Lisa, Ellyza Nasrul, and Andi Friadi. "The Difference of Zinc And Matrix Levels of Metalloproteinase-9 Serum Between Premature Rupture Of Membrane Aterm And Normal Pregnancy." Journal of Midwifery 4, no. 1 (2019): 40. http://dx.doi.org/10.25077/jom.4.1.40-50.2019.

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Premature rupture of membranes (PROM) is one of the common problems in the obstetric field, ranging from 8-10% of term pregnancies will experience PROM. The increase in MMP-9 also has an impact on the degradation of the extracellular matrix and the apoptotic process of amniotic epithelial cells which ultimately leads to membrane rupture. The purpose of this study was to determine the differences in serum zinc and MMP-9 levels between premature rupture of membranes and normal pregnancies.This research is quantitative observational with the cross-sectional design carried out in Independent Pract

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Gopinath, Sowmya, Nuzrin Nazar N, Bhavani M H, and Rekha Gurumurthy. "A prospective study of clinical profile of premature rupture of membranes and its effect on maternal and perinatal outcome at term gestation in primigravida." Panacea Journal of Medical Sciences 14, no. 2 (2024): 366–70. http://dx.doi.org/10.18231/j.pjms.2024.065.

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Premature rupture of membranes (PROM) is defined as the spontaneous rupture of amniotic membranes with a release of amniotic fluid, before the onset of labor. If it occurs after 37 weeks of gestation, it is called as term PROM. The incidence of PROM worldwide varies between 5-10%.Out of which 80% occurs at term. In India, the incidence of PROM was reported as 7-12% in all labours.This study was a prospective, observational hospital based study which include the cases admitted to labour ward, Department of Obstetrics, District hospital, Tumakuru, Karnataka with Premature rupture of membranes or

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Albab, Muhamad Ulil, Heriyanti Widyaningsih, Sri Hartini, and Ambarwati Ambarwati. "Incidence of Neonatal Asphyxia Events In Mothers Maternity With Early Ruptured Amniotic Fluid." South East Asia Nursing Research 2, no. 3 (2020): 99. http://dx.doi.org/10.26714/seanr.2.3.2020.99-104.

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Asphyxia and Intrauterine fetal dead (IUFD) are a threat if a premature rupture of membranes is not immediately treated quickly and appropriately. Neonatal asphyxia can occur due to complications from premature rupture of membranes. IMR in Indonesia is the fifth country for ASEAN countries, 35/1000 birth. Based on data from RA Kartini Hospital in Jepara, asphyxia cases from approximately (12,6%) and incidence of premature rupture of membranes 816 cases or around (85,8%). While the incidence of neonatal asphyxia born from PROM totalled 15 cases or about (1,6%). This research using quantitative

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Ramesh, T. V., Bineet Panigrahi, P. Pranaya, and P. Hima Bindu. "Outcome of neonates born to mothers with premature rupture of membranes." International Journal of Contemporary Pediatrics 5, no. 4 (2018): 1190. http://dx.doi.org/10.18203/2349-3291.ijcp20181994.

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Background: Premature rupture of membranes (PROM) is defined as rupture of membranes before the onset of labor which is caused by maternal intrauterine infection which increases with the duration of membrane rupture seen in one third cases of all preterm birth. The primary complication for the mother is risk of infection, complications for the newborn consists of prematurity, foetal distress, cord compression, deformation and altered pulmonary development. The present study was undertaken to evaluate the outcome of neonates born to mothers with PROM and know the incidence of adverse outcomes i

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Sharma, Sabita, Jayalaxmi Shakya, and Basanta Thapa. "Outcomes of Premature Rupture of Membrane Among Women Admitted in Teaching Hospital, Chitwan, Nepal." International Journal of Science and Healthcare Research 9, no. 1 (2024): 262–70. http://dx.doi.org/10.52403/ijshr.20240135.

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Background: Premature rupture of membranes is defined as rupture of membranes after 28th weeks of gestation before the onset of labor is called preterm PROM when it occurs after 37 completed weeks of gestation and before onset of labor, then it is term PROM. Spontaneous rupture of the membrane any time beyond 28th weeks of pregnancy but before the onset of labor is called Premature Rupture of Membrane (PROM). The management of maternal and fetal outcome in PROM is very important to decrease maternal as well as neonatal mortality and for better management and prevention of complications which h

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Widyandini, Meyska, Rena Oki Alestari, and Lelly Oktarina. "Analisis Hubungan Usia Kehamilan dan Riwayat KPD dengan Kejadian Ketuban Pecah Dini pada Ibu Bersalin di RSUD Dr. Doris Sylvanus Palangka Raya." Jurnal Surya Medika 8, no. 1 (2022): 168–71. http://dx.doi.org/10.33084/jsm.v8i1.3461.

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Premature rupture of membranes is declared if it occurs before the delivery process takes place. PROM is one of the causes of infection in mothers, the disease itself is the third cause of death in mothers. This study aims to determine the relationship between gestational age and history of PROM with the incidence of premature rupture of membranes (PROM). This study is an observational analytic with a case-control design. The population of this study was all mothers who gave birth to RSUD dr. Doris Sylvanus Palangka Raya with premature rupture of membranes as many as 225 mothers, and for the c

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Jatav, Deepika, and Nootan Chandwaskar. "ASSESSMENT OF FACTORS INCREASING THE RISK OF PRELABOUR RUPTURE OF MEMBRANES AND ITS EFFECT ON FETOMATERNAL OUTCOME." International Journal of Advanced Research 11, no. 07 (2023): 963–71. http://dx.doi.org/10.21474/ijar01/17305.

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Background: Premature rupture of membranes (PROM) refers to a patient who is beyond 37 weeks gestation and has presented with rupture of membranes (ROM) prior to the onset of labor. Patient with PROM presents with leakage of fluid, vaginal discharge and pelvic pressure, but they are not having contraction. It occurs in 3 percent of pregnancies and is the cause of approximately one third of preterm deliveries. It can lead to significant perinatal morbidity, including respiratory distress syndrome, neonatal sepsis, umbilical cord prolapse, placental abruption, and fetal death. Appropriate evalua

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Sulastri, Sulastri, and Meri Epriana Epriana. "Analisis Faktor Resiko Ketuban Pecah Dini Di Rsud Mukomuko Kabupaten Mukomuko Tahun 2021." JMNS 3, no. 2 (2022): 19–34. http://dx.doi.org/10.57170/jmns.v3i2.68.

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Premature rupture of membranes is very dangerous for pregnant women and their babies, the danger of premature rupture of membranes is infection occurs in mother and baby. The rupture of the membranes leaves the baby unprotected by the amniotic membrane and exposed to contact with the outside world, which causes bacteria to enter the mother's womb and infect both mother and baby. This can be life-threatening for both mother and baby. In addition, the birth of a baby that is less than the normal time causes premature babies and the risk of fetal defects is high. The purpose of this study was to

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Tri Harjati, Eny Sendra, Lumastari Ajeng Wijayanti, and Ririn Indriani. "Correlation between the Duration of Premature Rupture of Membranes during the Labor and the Asphyxia of Newborn Babies at Aura Syifa Hospital Kediri Regency." STRADA Jurnal Ilmiah Kesehatan 11, no. 2 (2022): 133–40. http://dx.doi.org/10.30994/sjik.v11i2.965.

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Premature Rupture of Membranes (PROM) is rupture of membranes more than one hour before onset of labor. One of the complications caused by PROM is asphyxia. The longer the rupture of the membranes the greater the risk of fetal distress. By the rupture of the membranes the amniotic fluid volume decreases and there is an emphasis on the umbilical cord so that there is less supply of oxygen and nutrients to the fetus which causes the newborn to have asphyxia.The purpose of this study was to determine the correlation between the length of premature rupture of membranes during labor with asphyxia o

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Muslicha, Ika, Vianty Mutya Sari, Siti Difta Rahmatika, and Wiwin Wiwin. "The Relationship between Premature Membrane Rupture and Neonatal Asphyxia at Gunung Jati Regional Hospital, Cirebon City." Jurnal Medisci 2, no. 3 (2025): 183–94. https://doi.org/10.62885/medisci.v2i3.604.

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One significant risk factor associated with the occurrence of Premature Rupture of Membranes (PROM) is Neonatal Asphyxia. Premature rupture of membranes is a condition where the amniotic membrane breaks before the onset of labor, which can lead to infections and other complications, including asphyxia in newborns. According to several studies, the incidence of PROM ranges from 2% to 20% of all pregnancies, with the incidence varying depending on various factors, including access to healthcare services and the medical conditions of pregnant women. Neonatal asphyxia is a condition where a newbor

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Mondal, Arnab, and Sanhita Kanoongo. "A study on management of premature rupture of membranes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (2018): 855. http://dx.doi.org/10.18203/2320-1770.ijrcog20180412.

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Background: Premature rupture of membranes (PROM) is a common obstetric complication. Knowledge of etiopathogenesis, diagnosis, complications and management of PROM has significantly increased due to extensive research in the recent past. Yet, there is no unanimous opinion regarding optimum management of PROM. The aim of the study was to observe the patients during labor and compare the latent period, duration of first stage of labor, modes of deliveries and the use of oxytocin and its outcome in PROM cases with controls. The study has been conducted with the belief that these data will help i

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Khonsa, Nurin Fauziah, and Ratna Wulandari. "PENGARUH PEKERJAAN TERHADAP KEJADIAN KETUBAN PECAH DINI PADA IBU HAMIL." Jurnal Ilmiah Pamenang 4, no. 2 (2022): 1–7. http://dx.doi.org/10.53599/jip.v4i2.103.

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Abstrak Ketuban Pecah Dini (KPD) atau Ketuban Pecah Sebelum Waktunya (KPSW) sering disebut dengan Premature Repture Of the Membrane (PROM) didefinisikan sebagai pecahnya selaput ketuban sebelum waktunya melahirkan. Pecahnya ketuban sebelum persalinan atau pembukaan pada kehamilan pertama jika pembukaan kurang dari 3 cm dan kurang dari 5 cm pada kehamilan kedua dan seterusnya . Hal ini dapat terjadi pada kehamilan cukup bulan maupun pada kehamilan kurang bulan. Dalam situasi ini, di mana risiko infeksi pada ibu dan anak meningkat, ketuban pecah dini merupakan masalah kebidanan yang penting, men

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Afanasiyeva, Marina Khivaliyevna, Vyacheslav Mikhaylovich Bolotskikh, and Viktoriya Olegovna Polyakova. "Premature rupture of membranes (modern view to etiology and pathogenesis, prediction perspectives)." Journal of obstetrics and women's diseases 63, no. 3 (2014): 4–11. http://dx.doi.org/10.17816/jowd6334-11.

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This article presents a review of contemporary views to biochemical, immunologic, genetic aspects to the etiology and pathogenesis of premature rupture of membranes (PROM). The article marks further ways in studying predictions of premature rupture of membranes at the advanced pregnancy periods.

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Safa, D. Jilan Haura, Adib Ahmad Shammakh, Dany Karmila, and Irwan Setyobudi. "The Relationship of Mother's Age, Parity, and Abnormalities in Fetal Location with The Incidence of Premature Ruptur of Membranes in The Regional Public Hospital of North Lombok." Jurnal Biologi Tropis 24, no. 1b (2024): 575–83. https://doi.org/10.29303/jbt.v24i1b.8252.

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Premature rupture of membranes (PROM) is one of the main causes of the high newborn mortality rates and maternal mortality rate (MMR), which continue to be significant global health challenges. The purpose of this study is to examine the association between the occurrence of PROM at the North Lombok Regional Public Hospital and maternal age, parity, and fetal anomalies. This research uses a case-control study design and is an analytical observational study. Purposive sampling was utilized to choose the research sample, which included 186 people in total. The chi-square test was used to analyze

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Nahar, Nurun, Nadira Haque, nahreen Akhtar, et al. "Maternal and Fetal Outcome in Term Premature Rupture of Membrane." Dinajpur Medical College Journal 18, no. 01 (2025): 25–30. https://doi.org/10.69861/djmcj2025v18i1s5.

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Abstract Background: Premature rupture of membranes (PROM) is a significant obstetric desperation.PROMrefers to the breakingof fetal membranes before the onset of labor, resulting in spontaneous leakage of amniotic fluid. PROM, which occurs before 37 weeks of gestation is defined as preterm PROM and PROM that occurs after 37 weeks of gestation is defined as term PROM. It is associated with detrimental maternal and perinatal consequence. Method: This cross-sectional observational study was carried out in the Department of Obstetrics & Gynecology, Bangabandhu Sheikh Mujib Medical University

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Novelia, Shinta, Tommy J Wowor, and Indriyani. "Factors Related to Premature Rupture of Membranes (PROM)." Health and Technology Journal (HTechJ) 1, no. 6 (2023): 582–88. http://dx.doi.org/10.53713/htechj.v1i6.117.

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One of the contributors to morbidity and mortality rates in mothers and babies is infection caused by premature rupture of membranes (PROM), where the amniotic membrane which is a barrier to the entry of germs that cause infection is no longer there and can be dangerous for the mother and fetus. This study aims to determine the factors associated with the incidence of premature rupture of membranes at the Ciruas Health Center in 2018. The study design is cross sectional. The population is 140 childbearing women who were in the Ciruas Health Centre during study period. 33 women were selected pu

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Lathifa, Shofia Nur, and Faizah Betty Rahayuningsih. "Factors Associated with the Incidence of Premature Rupture of Membranes." Indonesian Journal of Global Health Research 7, no. 1 (2025): 833–48. https://doi.org/10.37287/ijghr.v7i1.5450.

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Premature Rupture of Membranes (PROM) is a significant obstetric problem, characterised by rupture of the amniotic membrane before delivery, which has the potential to cause complications in maternal and infant health. Analyse the factors associated with the incidence of PROM in RSUD dr. Moewardi, Surakarta. This study used an analytic observational design with a cross-sectional approach. Inclusion criteria were medical records of pregnant women in September 2023 - August 2024. Exclusion criteria in the study were incomplete medical record data of pregnant women. A total of 200 medical records

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Shakya, Amshu, and Sweta Kumari Gupta. "Neonatal outcome of maternal premature rupture of membranes more than 18 hours." Journal of Kathmandu Medical College 9, no. 2 (2020): 81–86. http://dx.doi.org/10.3126/jkmc.v9i2.35526.

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Background: Premature Rupture of Membranes has been known to complicate pregnancy since ages. Several risk factors may be associated with occurrence of premature rupture of membranes. It is associated with varied neonatal complications, neonatal sepsis and prematurity being the most hazardous ones. Objectives: This study was conducted to evaluate the incidence of neonatal sepsis following premature rupture of membranes, risk factors and neonatal complications associated with premature rupture of membrane of more than 18 hours in the neonates admitted in a tertiary care center. Meth

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Sulistyowati, Sri, Yuniarsih Zakia та Soetrisno Khasan. "High MMP-9 and TNF-α expression increase in preterm premature rupture of membranes". Universa Medicina 35, № 1 (2016): 33. http://dx.doi.org/10.18051/univmed.2016.v35.33-39.

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<p>Preterm delivery is one of the causes of high perinatal morbidity and mortality. Matrix metalloproteinase 9 (MMP-9) is important for extracellular matrix (ECM) remodeling and may cause preterm labor and premature rupture of membranes (PROM). Tumor necrosis factor-α (TNF-α) as a pro-inflammatory cytokine plays a role in stimulating uterine activity and cervical ripening by degrading the ECM of the amniotic membranes through MMP-9. This study aimed to determine differences between MMP-9 and TNF-α expression of the membranes in preterm delivery with premature rupture of membranes (PPROM)

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Perinatal Outcome in Term Prelabour Rupture of Membranes – An Observational Study." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 4 (2024): 45–49. https://doi.org/10.5281/zenodo.15424293.

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<strong>Abstract</strong> <strong>Introduction</strong>: Prelabour rupture of membranes is the most challenging and controversial obstetric dilemma which occurs even in low risk pregnancies and can convert a traditional pregnancy into a high risk situation for both mother and fetus. As prelabour rupture of membranes is an obstetric condition associated with significant perinatal morbidity and mortality, so the purpose of this study is to analyze the perinatal outcome in prelabour rupture of membranes. <strong>Methods:</strong> This observational study was conducted in department of Obstetrics

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Balsak, Deniz, Fırat Aşır, Fatma Zehra Kurnuç, Elif Ağaçayak, and Murat Akkuş. "Histopathological Changes in The Placentas of Pregnant Women with Premature Rupture of Membranes (PROM) and Preterm PROM." Journal of Drug Delivery and Therapeutics 15, no. 7 (2025): 43–47. https://doi.org/10.22270/jddt.v15i7.7267.

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Introduction: Premature rupture of membranes (prom) and preterm prom (pprom) are critical obstetric complications associated with placental dysfunction. Histological changes in PPROM placentas have not been studied much in studies compared to PROM. This study aimed to investigates histopathological alterations in placental tissues of premature rupture of membranes of PROM and preterm PROM patients . Methods: This experimental non-randomized case-control study was conducted with 30 PROM patients , PPROM pregnant women and 30 healthy pregnant women at Dicle University Faculty of Medicine between

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Mondal, Arnab, Rupak Ranjan Roy, and Asok Kumar Mondal. "A Study on Management of Premature Rupture of Membranes (PROM)." Bangladesh Journal of Obstetrics & Gynaecology 32, no. 2 (2020): 94–98. http://dx.doi.org/10.3329/bjog.v32i2.48280.

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Background: Premature rupture of membranes (PROM) is a common obstetric complication. Knowledge of etiopathogenesis, diagnosis, complications & management of PROM has increased due to extensive research in the recent past. Yet, there is no unanimous opinion regarding optimum management of PROM. The aim of the study was to observe the patients during labor and compare the latent period, duration of first stage of labor, modes of deliveries and the use of oxytocin and its outcome in PROM cases with controls. Materials and methods: In this study, the definition of PROM used is – rupture

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Sengar, Mahima, and Ruchi Kalra. "Identification of risk factors of premature rupture of membrane at a tertiary care centre: a case-control study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 14, no. 6 (2025): 1884–90. https://doi.org/10.18203/2320-1770.ijrcog20251579.

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Background: Premature rupture of membranes (PROM) is a critical issue in obstetrics, occurring in 3-4% of pregnancies and accounting for 40-50% of preterm births. This study aims to identify risk factors associated with premature rupture of membranes in women who deliver at tertiary care centre. Methods: This research is a case-control study conducted with 240 women at the Department of Obstetrics and Gynaecology, People's College of Medical Sciences and Research Institute, Bhopal. The study comprised 80 cases and 160 controls in a 1:2 ratio. Results: There were no significant demographic diff

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Bukhoeri, Ahmad, Syarief Thaufik Hidayat, Ediwibowo Ambari, Julian Dewantiningrum, Putri Sekar Wiyati, and Besari Adi Pramono. "Differences of Ampicillin and Cefazolin Effects in Reducing hs-CRP Level in Premature Rupture of Membranes." Diponegoro International Medical Journal 2, no. 1 (2021): 1–5. http://dx.doi.org/10.14710/dimj.v2i1.8428.

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Background: Premature rupture of membranes (PROM) is a rupture of amniotic sac before delivery. PROM is associated with an increased incidence of preterm labor and infection. The use of prophylactic antibiotic may reduce the risks of infection. High-sensitivity C-reactive protein (hs-CRP) is an acute-phase reactant protein that is associated with PROM. How much effect of prophylactic antibiotic to hs-CRP level remains unclear.Objective: To compare the reduction in hs-CRP levels in premature rupture of membranes before and after given ampicillin or cefazolin.Methods: The design of this study wa

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ROBERTS, DEVENDER. "AMNIOINFUSION FOR VERY EARLY RUPTURE OF MEMBRANES." Fetal and Maternal Medicine Review 22, no. 3 (2011): 207–18. http://dx.doi.org/10.1017/s0965539511000106.

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Premature rupture of membranes (PROM) is a major cause of perinatal mortality and morbidity associated with preterm delivery in a third of cases. Fetal survival is even more compromised when the membranes rupture early in the second trimester (very early PROM). Survival is associated with problems of delivery of the very preterm fetus as well as associated risks of feto-maternal infection. In the context of studies of amnioinfusion, very early rupture of membranes is defined as rupture between 16 and 26 weeks of pregnancy.

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