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1

Louderback, Hunter. "AN ANALYSIS OF A MULTIVALENT HEROIN AND PRESCRIPTION OPIOID VACCINE." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1458909859.

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Ancona, Rachel M. "Prescribed Opioids as an Initial Exposure in Emergency Department Patients Reporting Nonmedical Opioid or Heroin Use." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1459244023.

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3

Goodin, Amie. "EVALUATING STATE POLICY INTERVENTIONS FOR OPIOID ABUSE AND DIVERSION: THE IMPACT ON CONSUMERS, HEALTHCARE PROVIDERS, AND THE U.S. MARKET FOR PRESCRIPTION OPIOIDS." UKnowledge, 2015. http://uknowledge.uky.edu/msppa_etds/14.

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Prescription opioid pain reliever utilization has been increasing since the 1990s, due in part to changes in recommendations for the treatment of chronic pain, but also to abuse and diversion. One innovative policy solution to the abuse and diversion of prescription opioids is state prescription drug monitoring programs (PDMPs), which provide prescribers and other selected parties with patient controlled substance dispensation history; thereby, correcting an information asymmetry problem between prescribers and patients. The widespread implementation of state PDMPs, which vary in program desig
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Ashrafioun, Lisham. "An Evaluation of the Impact of Cue Exposure on the Relationship Between Pain Level and Craving For Prescription Opiods." Bowling Green State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1384220597.

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5

Genberg, Jenny. "Prescription of opioids and benzodiazepines for breathlessness in interstitial lung disease : A national population-based study." Thesis, Umeå universitet, Institutionen för integrativ medicinsk biologi (IMB), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-170027.

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6

Pack, Robert P., Angela Hagaman, and Nicholas Hagemeier. "Forum hosts: Tennessee State Task Force on Opioids." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1340.

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7

Lieb, Roselind, Hildegard Pfister, and Hans-Ulrich Wittchen. "Use, Abuse and Dependence of Prescription Drugs in Adolescents and Young Adults." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-99916.

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Lifetime prevalence estimates of psychotropic medicine use as well as prevalence of DSM-IV prescription drug use disorders from the baseline investigation of the Early Developmental Stages of Psychopathology (EDSP) Study are presented. Use of prescription medication at some time in their life was reported by 27.4% of the respondents. Illicit use of prescription drugs, which means an intake without medical legitimation, was reported by 4.5% of the sample. The findings suggest that abuse of and dependence on prescription drugs, with most cases reporting polysubstance use, is quite rare in the 14
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Neelakantan, Harshini. "REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/270439.

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Pharmaceutical Sciences<br>Ph.D.<br>Pain is a leading cause of disability and the most common reason for clinical care. The field of pain research has focused on sex differences in the recent years with an expansive body of literature demonstrating sex-related differences in pain behavior and responsiveness to pharmacological interventions. Prescription opioids are potent analgesics and the mainstay for the clinical management of moderate-to-severe acute and chronic pain conditions. However, the long-term clinical use of prescription opioids for chronic pain remains controversial due to concer
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9

Tam, Cheuk Chi. "CONSTRUCTION AND VALIDATION OF A NON-MEDICAL USE OF PRESCRIPTION OPIOIDS OUTCOME EXPECTANCIES SCALE AMONG COLLEGE STUDENTS IN CHINA." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/6009.

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Background:Non-medical use of prescription opioids (NMUPO) has become a clear threat to public health. Young adults (aged 18 to 25) have a high risk of NMUPO. My prior work on Chinese undergraduates indicates a high prevalence of lifetime NMUPO (49.2%). Health behavior theories propose that outcome expectancies are robust psychosocial determinants of substance use. Literature has identified the influence of outcome expectancies on alcohol and drug use. However, the role of outcome expectancies in NMUPO in China is unknown, and a scarcity of a valid measures for NMUPO outcome expectancies may b
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10

Lieb, Roselind, Hildegard Pfister, and Hans-Ulrich Wittchen. "Use, Abuse and Dependence of Prescription Drugs in Adolescents and Young Adults." Karger, 1998. https://tud.qucosa.de/id/qucosa%3A26268.

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Lifetime prevalence estimates of psychotropic medicine use as well as prevalence of DSM-IV prescription drug use disorders from the baseline investigation of the Early Developmental Stages of Psychopathology (EDSP) Study are presented. Use of prescription medication at some time in their life was reported by 27.4% of the respondents. Illicit use of prescription drugs, which means an intake without medical legitimation, was reported by 4.5% of the sample. The findings suggest that abuse of and dependence on prescription drugs, with most cases reporting polysubstance use, is quite rare in the 14
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11

Briggs-Bolling, Izetta Mounice. "Non Medical Prescription Drug use in Rural Communities and Social Work." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4424.

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This study explored the roles and responsibilities of social workers providing services to nonmedical prescription drug users (NMPDU). Researchers have indicated NMPDU disproportionately affects people living in rural communities. The overarching research question sought to explore the concerns of social workers when providing services to patients coping with NMPDU in the rural community of Ulster County, New York. The intention was to examine systemic challenges facing rural social workers when attempting to decrease morbidity risks and increase the health of Ulster County residents. A total
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Floyd, David C. Mr. "Making "The Gray Area": Transitioning from Print Journalism to Documentary Filmmaking." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/honors/390.

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In my senior year at ETSU I produced a documentary about opioid abuse in East Tennessee. In 2016, two local health care providers and a university collaborated on a project that would bring an opioid treatment center to Gray, Tennessee. The center includes a methadone clinic, an addition that piqued the concern of many citizens living in Gray. The film evaluates the concerns citizens had about the clinic and explores the issue of opioid abuse in East Tennessee.
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Nibert, Mary E. "The key reasons why or why not prescribing providers of opioids access the Ohio Automated Rx Reporting System (OARRS)." Franklin University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=frank1600805500975207.

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14

Clough, Robin Jo. "Gender and Prescription Painkiller Misuse: Findings from the 2011 National Survey on Drug Use and Health." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/1939.

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This study examines the effects of gender and social bonds on the experience of prescription painkiller misuse for men and women. The theoretical framework for the project is Travis Hirschi's social control theory (1969), and the social bond elements of attachment, commitment, involvement, and belief, which emphasizes the importance of these bonds in creating a "stake in conformity" for the individual, leading to acceptance of social norms and desistence from deviance. This theory, however, is relatively silent with regard to gender differences and was developed to examine delinquency in an al
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Ramirez, Enrique. "Opioid Prescribing Practices Following Pediatric Dental Procedures in Ohio." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1593441575248724.

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16

Samaila, Daniel. "Living Arrangements, Referral Source and Young Adult Admissions to Drug Treatment." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6660.

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Abuse of painkiller drugs and non-medical use of drugs among young adults continues to be a public health crisis in the United States. Living arrangements and source of treatment referral were considered as the social context that could contribute to increased admissions to treatment for drug abuse. The purpose of this study was to examine the relationship between, independent living arrangement, the principal source of referral, and abuse of opioid, heroin, and cocaine. Steered by the conceptual framework of the biopsychosocial model, this study used the data from the 2015 Treatment Episode D
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17

Haslam, Valynn Christina. "Opioid Prescription and Use After Laparoscopic Cholecystectomy." BYU ScholarsArchive, 2017. https://scholarsarchive.byu.edu/etd/6889.

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Background: Opioid abuse has become a serious public health issue. While adequate pain management is an ethical responsibility for health care providers, responsible stewardship of controlled substances is of equal concern. Opioids are often prescribed for treatment of acute pain post-operatively. The purpose of this study is to examine opioid prescription practices and use of opioids after laparoscopic cholecystectomy. Methods: A convenience sample of 42 patients scheduled for laparoscopic cholecystectomy were enrolled in the study. Using a descriptive study design, patients were interviewed
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18

Jefferies, Stella Kiah. "Medication-Assisted Therapy Interventions and Prescription Opioid Misuse." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/6223.

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Opioid drug misuse and dependence are a social and public health problem in the United States. Prescription opioid abuse and misuse have been associated with substantial morbidity and mortality rates as well as social and economic costs. The purpose of this project was to provide a systematic review of literature on the effectiveness of medication-assisted therapy interventions in addressing the problem of prescription opioid misuse in health care settings. The systematic review was completed through a literature search conducted across five electronic databases. The review was guided by the h
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19

Almanie, Sarah. "Prescription Drug Monitoring Programs and Opioid Poisoning: Evaluating the Impact of Prescriber Use Mandates on Prescription Opioid Poisoning Emergency Department Visits." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5545.

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Introduction: Prescription drug monitoring programs (PDMPs) are one strategy established to curb the prescription opioid abuse epidemic. Prescriber use mandates has emerged as a promising practice to increase PDMPs impact on prescription opioid abuse; however, evidence of its effectiveness has not yet been established. Kentucky was the first state to implement comprehensive prescriber use mandates in July 2012. Objective: To assess the relationship between prescriber use mandates policy and emergency department (ED) visits related to prescription opioid poisoning among adults in Kentucky and N
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20

Hagemeier, Nicholas E., J. Nile Barnes, and Kasey Strey. "The Prescription Opioid Epidemic: How it Happened and Solutions." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1414.

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Rates of prescription drug misuse in Texas are alarmingly high. One in five Texas high school students have taken prescription drugs without a doctor’s prescription. In 2015, Texas had the second highest total healthcare costs from opioid abuse in the nation ($1.96 billion), and Texas is home to four of the top 25 cities in the U.S. for opioid abuse. Meanwhile, only one in three prescribers is using the statewide Prescription Drug Monitoring Program (PDMP), leading to a massive loss of data. There is substantial need for increased infrastructure and prevention measures in Texas, especially rel
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21

Hagemeier, Nicholas E., Arsham Alamian, Matthew M. Murawski, Heather Flippin, Elizabeth J. Hagy, and Robert P. Pack. "Correlates of Prescription Opioid Legitimacy Judgments Among Community Pharmacists." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/1321.

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Background: Community pharmacists are legally required to evaluate and confirm the legitimacy of prescription opioids (POs) prior to dispensing. Yet, previous research has indicated community pharmacists perceive nearly 50% of dispensed POs to be issued lacking a legitimate medical purpose. Objective: To analyze correlates of PO legitimacy judgments across pharmacist and pharmacy setting characteristics. Methods: A cross-sectional study of 2000 Tennessee pharmacists was conducted during October and November of 2012. Community pharmacists' self-reported attitudes, beliefs, and behaviors specifi
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22

Nelson, Renee. "Neurocognitive Examination of Attentional Bias and Inhibitory Control Alterations in Prescription Opioid Dependence." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37478.

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Prescription opioid (PO) abuse is a growing public health concern worldwide as evidenced by an increasing number of opioid-related hospital admissions with a striking lack of research examining the neural basis underlying cognitive symptomatology. Drugs of abuse, through their impact on the dopaminergic system, are thought to disrupt the cognitive network regulating impulse control and incentive salience through inhibition of goal-oriented behaviour and drug-induced attentional biases. The objective of the present study is to examine neurocognitive processes in PO abusers (vs. healthy controls
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23

Hagemeier, Nicholas E., Arsham Alamian, M. M. Murawski, Robert P. Pack, H. Flippin, and H. Hagy. "Correlates of Prescription Opioid Legitimacy Estimations among Community Pharmacists in Tennessee." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/1362.

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24

Kinney, Olivia. "Impact of Community-based Pharmacist Intervention on Initial Opioid Prescribing." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1602153052809053.

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25

Calônego, Marco Antônio Marchetti. "Dificuldades sociais, legais e burocráticas para prescrição de opioides." Botucatu, 2020. http://hdl.handle.net/11449/192414.

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Orientador: Guilherme Antonio Moreira de Barros<br>Resumo: Introdução: A dor é uma experiência pessoal, subjetiva, que envolve aspectos sensitivos e culturais que podem ser alterados pelas variáveis socioculturais e psíquicas do indivíduo, do meio e, apesar de classificações diversas, geralmente relacionada ao sofrimento. No Brasil estudos indicam que, embora cerca de 50% dos pacientes portadores de dor estejam medicados, a maior parte deles está descontente com os resultados do tratamento. Em situação de dor aguda traumática, apenas 7% dos pacientes tem suas dores totalmente aliviadas e, em p
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26

Kaplan, Rachel S. W. "The Rhetoric of the Opioid Crisis and Addiction to Prescription Pain Medicine." Thesis, Duquesne University, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10787609.

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<p> In this historical moment, the United States is amidst an opioid crisis killing the young and the old; at least seventy-eight people die every day from an opioid-related overdose (Enomoto in Murthy III). Changing mindsets of the doctors who prescribe opioids is just as important as asking the patients who are prescribed them to demand an alternative medication. The different parties involved in the crisis all have a different agenda and their rhetorical bias is explored throughout this project. The pharmaceutical companies have launched aggressive marketing campaigns expressing the benefit
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Hagemeier, Nicholas E., Fred Tudiver, Scott Brewster, et al. "Interprofessional Prescription Opioid Abuse Communication Among Prescribers and Pharmacists: A Qualitative Analysis." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1323.

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Background: Prescribers and community pharmacists commonly perceive prescription opioid abuse to be a problem in their practice settings and communities. Both cohorts have expressed support for interventions that improve interprofessional communication and reduce prescription opioid abuse. The objective of this study was to describe prescription opioid abuse-related communication among and between prescribers and community pharmacists in South Central Appalachia. Methods: The investigators conducted five focus groups with 35 Appalachian Research Network practice-based research network provider
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Melton, Sarah, and Nicholas E. Hagemeier. "Prescription Drug Abuse: Regional Realities and Recommendations." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/1419.

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29

Newman, William. "Slaying the Dragon: An Analysis of State and Federal Policies on Battling the United States Opioid Epidemic." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1879.

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The opioid crisis has reached unprecedented levels with the rise in deaths rising fivefold from 2001. The crisis’ has effected many communities throughout the United States and requires deep intervention in order to minimize the number of individuals dying from opioids. The heart of the problem lies in prescription opioids and heroin, one cannot talk about prescription opioids without speaking of the dangers of heroin. The purpose of this thesis is to examine the results of state and federal policies in handling the epidemic and recognizing the need for a comprehensive, multi-tiered strategy f
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Miracle, Tessa. "Physician’s knowledge, attitudes, and utilization of the Prescription Drug Monitoring Program." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1593171776627526.

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31

Sueker, Judah. "Impact of Patient Prescription History on Emergency Department Opioid Prescribing for Acute Pain." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17295907.

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With prescription opioid abuse having reached epidemic proportions, Emergency Department clinicians must assess the safety of prescribing opioid pain medication to patients for whom they have limited information or history. Prescription Drug Monitoring Programs (PDMPs) may provide information that impacts prescribing. In an online survey, 37 emergency physicians and physician assistants indicated their likelihood to prescribe opioids to three fictional patients with acute, non-cancer pain before and after reviewing each patient’s PDMP profile. Our main finding is that respondents were less l
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32

Loveday, William A. "Prescription opioid analgesic drug misuse: What can we learn from doctor-shopping behaviour." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/108061/1/William_Loveday_Thesis.pdf.

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This thesis examined the phenomenon of 'doctor shopping' for prescription opioid drugs in Queensland to identify whether aspects of this behaviour could be used better identify drug misuse and to assist doctors in better treatment of patients. Findings suggest that doctor shopping is a complex and uncommon behaviour in patients receiving prescription opioid drugs and not necessarily associated with aberrant drug use. It appears that long-term high dose use of prescription opioids is a greater indicator of concern and potential risk of harm. These outcomes have relevance to the implementation o
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Pack, Robert P. "Opioid Use Disorder." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1335.

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Lvovschi, Virginie-Eve. "Titration morphinique inhalée aux Urgences : modernisation de la prise en charge des douleurs sévères de l'adulte Targeting moderate pain in healthy volunteers by individual calibration of a nociceptive flexion reflex model Proposer un "modèle" de douleur provoquée par Electromyogramme pour optimiser les outils antalgiques aux urgences Nebulized versus intravenous morphine titration for the initial treatment of severe acute pain in the emergency department : study protocol for a multicenter, prospective randomized and controlled trial, CLIN-AEROMORPH Inhaled versus intravenous opioid dosing for the initial treatment of severe acute pain in the emergency department : pharmacological intermediate results of the CLIN-AEROMORPH french study Toward new eligibility criteria for ontravenous morphine in the French Emergency Department : Evaluation of physicians' bedside rationalization of opioid titration protocols Analysis of bedside determinisms leading to under-prescription of morphine titration in the Emergency Department : EPIMORPH study Medico-economic study of pain in an emergency department : a targeted literature review Opioid reflex at triage is not a solution for opioid-naive patients in emergency departments A systemic approach to complete the multimodal assessment model of pain Intravenous morphine titration to treat severe pain in the ED Morphine consumption is not modified in patients with severe pain and classified by the DN4 score as neuropathic Prise en charge de la douleur aiguë spontanée de l'adulte aux urgences." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMR013.

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Notre objectif était d’optimiser la prise en charge de la douleur aiguë sévère en médecine d’urgence. La titration morphinique intraveineuse qui fait actuellement référence doit se moderniser pour répondre aux nouveaux enjeux de la pratique en même temps que l’on doit garantir une balance bénéfice risque inchangée dans la lutte contre l’oligoanalgésie. Le travail décrit dans cette thèse, constitue une première étape d’évaluation d’une alternative nébulisée à la titration morphinique, à travers 3 études cliniques (AEROMORPH1, CLIN-AEROMORPH, EPIMORPH) et l’étude de son contexte dans la littérat
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Salwan, Aaron J., Nicholas E. Hagemeier, and Sam Harirforoosh. "Abuse-Deterrent Opioid Formulations: A Key Ingredient in the Recipe to Prevent Opioid Disasters?" Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2763.

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The US Food and Drug Administration (FDA) is encouraging the innovation of long-acting opioid formulations that are manipulation-resistant. The purpose of this commentary is to assess the benefits and limitations of abuse-deterrent opioid formulations (ADFs) and discuss their role in mitigating the current opioid epidemic. ADFs have been created with chemical properties that make it difficult for people who non-medically use prescription drugs to crush and dissolve opioid tablets, as well as by combining opioids with antagonists such as naloxone or naltrexone, which are released only when the
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Gatley, Samuel. "The Impact of Prescription Drug Monitoring Programs on the Dynamics of the Opioid Epidemic." Thesis, Rochester Institute of Technology, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10261352.

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<p> The forces driving the prescription opioid epidemic currently raging across the United States include aggressive marketing, weak regulation, addiction, freely prescribing doctors, a glut of pills available for sharing, and easy access to illicit drugs like heroin. This thesis aims to quantitatively analyze the interactions between these drivers through construction of a System Dynamics model, in order to determine the efficacy of policy intervention through Prescription Drug Monitoring Programs. The System Dynamics model simulates the flow of doctors&rsquo; prescriptions to the two very di
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Luu, Huong T. T. "USING PRESCRIPTION DRUG MONITORING DATA TO INFORM POPULATION LEVEL ANALYSIS OF OPIOID ANALGESIC UTILIZATION." UKnowledge, 2018. https://uknowledge.uky.edu/epb_etds/21.

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Increased opioid analgesic (OA) prescribing has been associated with increased risk of prescription opioid diversion, misuse, and abuse. States established prescription drug monitoring programs (PDMPs) to collect and analyze electronic records for dispensed controlled substances to reduce prescription drug abuse and diversion. PDMP data can be used by prescribers for tracking patient’s history of controlled substance prescribing to inform clinical decisions. The studies in this dissertation are focused on the less utilized potential of the PDMP data to enhance public health surveillance to mon
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38

Agbevey, Edward Worlanyo. "Impact of Emergency Department Prescriber Type on the Rate of U.S. Opioid Prescriptions." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7110.

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Many drug overdoses in the United States are from prescription drugs, most of which are classified as opioid pain relievers (OPRs) and commonly prescribed in emergency departments (EDs) to treat pain. OPR abuse and addiction is a major public health issue. Researchers have identified the role of various patient characteristics (race, gender, demographics, etc.) in the variation in OPR prescription rates, but the contribution of provider-type differences to that variation has not been exposed. The purpose of this study was to evaluate the strength of the association between provider type and th
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Gonzalez, Mabel Gonzalez. "Factors related to prescription drug abuse among young adults in Florida." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2821.

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A lack of available data exists regarding environmental factors related to prescription drug abuse (PDA), which could explain the ineffectiveness of efforts to reduce PDA in Florida. Prescription drug abuse among adults older than age 18 varies with the level of education achieved, and these metrics potentially reflect socioeconomic differences. The purpose of this quantitative study was to examine the connections between contextual aspects of prescription opioid abuse among Florida's middle and high school students to understand youth PDA in relation to their environments. This study consiste
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Pauly, Nathan James. "INVESTIGATING THE ROLE OF PRESCRIPTION DRUG MONITORING PROGRAMS IN REDUCING RATES OF OPIOID-RELATED POISONINGS." UKnowledge, 2018. https://uknowledge.uky.edu/pharmacy_etds/84.

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The United States is in the midst of an opioid epidemic. In addition to other system level interventions, almost all states have responded to the crisis by implementing prescription drug monitoring programs (PDMPs). PDMPs are state-level interventions that track the dispensing of Controlled Substances. Data generated at the time of medication dispensing is uploaded to a central data server that may be used to assist in identifying drug diversion, medication misuse, or potentially aberrant prescribing practices. Prior studies assessing the impact of PDMPs on trends in opioid-related morbidity h
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41

Griffin, Patricia Griffin. "Resilience in Police: Opioid Use and the Double-Edged Sword." Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/431414.

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Criminal Justice<br>Ph.D.<br>Public health officials have declared the widespread use and misuse of prescription opioid medications an epidemic in the United States. The director of the Centers for Disease Control and Prevention (CDC), Dr. Tom Frieden, has stated, “We know of no other medication routinely used for a nonfatal condition that kills patients so frequently” (Frieden & Houry, 2016, p. 1503). The present study was prompted by the concern that there is no empirical data on how law enforcement officers have been affected by the use of opioids. It is the first empirical examination of h
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Mathis, S., Angela Hagaman, David Kirschke, and Nicholas E. Hagemeier. "Carter County, Tennessee: A Rural Community’s Response to Opioid Overdose Deaths." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/1444.

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43

Dipzinski, Aaron. "Comparison of Washington state 2010 Medicare prescription drug plan coverage of pharmacotherapies for opioid and alcohol dependence." Pullman, Wash. : Washington State University, 2010. http://www.dissertations.wsu.edu/Thesis/Spring2010/A_Dipzinski_042310.pdf.

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Thesis (M.H.P.A.)--Washington State University, May 2010.<br>Title from PDF title page (viewed on July 22, 2010). "Department of Health Policy and Administration." Includes bibliographical references (p. 42-51).
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44

Dickerson, Steven. "The Effects of Recreational Marijuana Legislation on the Opioid Epidemic in Washington State." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1757.

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This paper analyzes the impact of the 2012 legalization of recreational marijuana in Washington State on opioid abuse. Using synthetic control methodology, this paper finds that the legislation prevented 638 overdose deaths and lead to over 3,600 individuals seeking treatment for opioid abuse disorders. Due to the large health, social, and economic impacts of the opioid epidemic, further research should be conducted into ways to reduce the number of opioid prescriptions, the number of opioid overdoses, and opioid abuse generally.
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Pack, Robert P. "Opioid Use in Tennessee: Lessons Learned." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/1342.

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46

Langenfeld, Natalie Rose. "A novel sequential ABC algorithm with applications to the opioid crisis using compartmental models." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6171.

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The abuse of and dependence on opioids are major public health problems, and have been the focus of intense media coverage and scholarly inquiry. This research explores the problem in Iowa through the lens of infectious disease modeling. We wanted to identify the current state of the crisis, factors affecting the progression of the addiction process, and evaluate interventions as data becomes available. We introduced a novel sequential Approximate Bayesian Computation technique to address shortcomings of existing methods in this complex problem space, after surveying the literature for availab
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47

Lake, Stephanie Louise. "Illicit prescription opioid injection : prevalence, characteristics, and health outcomes among people who inject drugs in Vancouver, Canada." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54037.

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Background: The use of prescription opioid (PO) painkillers has increased substantially in Canada and the United States over the previous two decades, bringing widespread public health concern related to non-medical PO use and overdose. Meanwhile, the injection of POs has become common among illicit drug-using populations. This thesis sought to outline the health outcomes associated with injecting POs; evaluate the impact of PO injection on non-fatal overdose; and identify the characteristics associated with PO injection among HIV-positive individuals who use injection drugs (IDU). Methods: A
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48

Hagemeier, Nicholas E., Matthew M. Murawski, Nicolas C. Lopez, Arsham Alamian, and Robert P. Pack. "Theoretical Exploration of Tennessee Community Pharmacists' Perceptions Regarding Opioid Pain Reliever Abuse Communication." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/1329.

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Background: Community pharmacists are a key intervention point in efforts to prevent and mitigate the impact of prescription drug abuse and misuse (PDA/M); yet pharmacists' perceptions regarding PDA/M have been explored only briefly in the literature. Objectives: 1) To explore Tennessee community pharmacists' perceptions regarding opioid pain reliever (OPR) prescribing, dispensing and abuse; 2) to explore community pharmacists' self-efficacy beliefs regarding PDA/M-specific communication; and 3) to evaluate perceived barriers to engaging patients in PDA/M-specific communication. Methods: A 55-
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Pack, Robert P. "Lessons Learned a Decade into the Opioid Epidemic." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/1338.

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50

Jones, Christopher McCall. "Estimating the Magnitude and Characteristics of Prescription Opioid Injection Misuse and the Role of Syringe Services Programs in Response to the Opioid Crisis in the United States." Thesis, The George Washington University, 2019. http://pqdtopen.proquest.com/#viewpdf?dispub=13806240.

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<p> The United States is experiencing an unprecedented crisis of prescription and illicit opioid misuse, addiction and overdose. Coincident with the increase in opioid misuse and addiction in the U.S. over the past decade are rising rates of prescription opioid injection and transmission of infectious diseases such as hepatitis C virus (HCV) and endocarditis. </p><p> Following the 2015 HIV outbreak in Scott County, Indiana associated with injection of the prescription opioid oxymorphone, and a decade-long increase in viral hepatitis infection rates, especially in areas of the U.S. with long-
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