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1

Allanore, Yannick, and Andre Kahan. "Primary Heart Involvement in Systemic Sclerosis." Current Rheumatology Reviews 2, no. 3 (2006): 245–49. http://dx.doi.org/10.2174/157339706778019593.

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2

Kumar, Susheel. "Skin Involvement in Primary Systemic Amyloidosis." Mediterranean Journal of Hematology and Infectious Diseases 5, no. 1 (2013): e2013005. http://dx.doi.org/10.4084/mjhid.2013.005.

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Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We report a case of primary systemic amyloidosis with multiple, non-itchy, papular lesions in lower eyelids and lower chest wall bilaterally. Diagnosis was confirmed in this case by biopsy of skin lesions using congo red staining. Papular eruptions as seen in index patient are relatively uncommon form
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3

Ross, Laura, David Prior, Susanna Proudman, Alessandra Vacca, Murray Baron, and Mandana Nikpour. "Defining primary systemic sclerosis heart involvement: A scoping literature review." Seminars in Arthritis and Rheumatism 48, no. 5 (2019): 874–87. http://dx.doi.org/10.1016/j.semarthrit.2018.07.008.

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4

Flores-Umanzor, Eduardo Josué, Paula Sánchez-Somonte, Ana García-Álvarez, and Marta Farrero. "Heart failure due to primary cardiac involvement in systemic sclerosis." Cardiocore 53, no. 1 (2018): 42–44. http://dx.doi.org/10.1016/j.carcor.2016.10.001.

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5

Trukhin, Ivan V., Dmitrij Yu Schekochikhin, Nina A. Novikova, et al. "Heart involvement in AL-amyloidosis. Current state of the issue." Annals of the Russian academy of medical sciences 74, no. 5 (2019): 307–16. http://dx.doi.org/10.15690/vramn1184.

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AL cardiac amyloidosis is a relatively rare disorder that belongs to the group of infiltrative cardiomyopathies. Diagnosis of primary amyloidosis is challenging due to many unspecific symptoms and sings, which often leads to late diagnosis when treatment options are limited. Primary amyloidosis particularly needs to be excluded in patients with heart failure with preserved ejection fraction. Therapy in cardiac amyloidosis has to main vectors: 1) chemotherapy to eliminate amyloidogenic plasmatic cells 2) heart failure treatment. The main challenge for cardiologists is to support hemodynamics un
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6

Bruni, Cosimo, Maya H. Buch, Daniel E. Furst, et al. "Primary systemic sclerosis heart involvement: A systematic literature review and preliminary data-driven, consensus-based WSF/HFA definition." Journal of Scleroderma and Related Disorders 7, no. 1 (2021): 24–32. http://dx.doi.org/10.1177/23971983211053246.

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Introduction: Primary heart involvement in systemic sclerosis may cause morpho-functional and electrical cardiac abnormalities and is a common cause of death. The absence of a clear definition of primary heart involvement in systemic sclerosis limits our understanding and ability to focus on clinical research. We aimed to create an expert consensus definition for primary heart involvement in systemic sclerosis. Methods: A systematic literature review of cardiac involvement and manifestations in systemic sclerosis was conducted to inform an international and multi-disciplinary task force. In ad
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7

Boldueva, S. A., I. V. Yarmosh, N. S. Shvets, and V. V. Grokhotova. "Primary systemic amyloidosis with involvement of the heart valued like hypertrophic cardiomyopathy." Kreativnaya kardiologiya 12, no. 3 (2018): 275–83. http://dx.doi.org/10.24022/1997-3187-2018-12-2-275-283.

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8

Kaderli, A. A., I. Baran, O. Aydin, et al. "Diffuse involvement of the heart and great vessels in primary cardiac lymphoma." European Journal of Echocardiography 11, no. 1 (2009): 74–76. http://dx.doi.org/10.1093/ejechocard/jep111.

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9

Rogowitz, Elisa, Hani M. Babiker, Ravitharan Krishnadasan, Clint Jokerst, Thomas P. Miller, and Michael Bookman. "Heart of Lymphoma: Primary Mediastinal Large B-Cell Lymphoma with Endomyocardial Involvement." Case Reports in Oncological Medicine 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/814291.

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Primary mediastinal B-cell lymphoma (PMBCL) is an uncommon aggressive subset of diffuse large B-cell lymphomas. Although PMBCL frequently spreads locally from the thymus into the pleura or pericardium, it rarely invades directly through the heart. Herein, we report a case of a young Mexican female diagnosed with PMBCL with clear infiltration of lymphoma through the cardiac wall and into the right atrium and tricuspid valve leading to tricuspid regurgitation. This was demonstrated by cardiac MRI and transthoracic echocardiogram. In addition, cardiac MRI and CT scan of the chest revealed the lar
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10

Said, Sameh M., Prabhjot Nijjar, Molly Klein, and Ranjit John. "Left bundle branch block revealing a primary small bowel carcinoid metastasizing to the interventricular septum." Interactive CardioVascular and Thoracic Surgery 31, no. 3 (2020): 408–10. http://dx.doi.org/10.1093/icvts/ivaa099.

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Abstract Carcinoid tumours of the heart occur most commonly as a result of metastatic disease and usually affect the right side of the heart. We report a case of a solitary carcinoid metastasis to the interventricular septum without hepatic involvement in a 74-year-old man.
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11

Ikic, A., E. Chatelus, E. Epailly, et al. "AB0607 Heart Transplantation in 2 Patients with Systemic Sclerosis and Primary Cardiac Involvement." Annals of the Rheumatic Diseases 73, Suppl 2 (2014): 1006.3–1007. http://dx.doi.org/10.1136/annrheumdis-2014-eular.3894.

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12

Agarwal, Chirag, Sunny Goel, Eric Stern, et al. "Carcinoid Heart Disease without Liver Involvement Caused by a Primary Ovarian Carcinoid Tumour." Heart, Lung and Circulation 24, no. 7 (2015): e97-e100. http://dx.doi.org/10.1016/j.hlc.2015.02.014.

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13

Bachour, Kinan, Sagar Shah, Jennifer Chia, et al. "PRIMARY CARDIAC LYMPHOMA WITH LOCOREGIONAL LYMPH NODE INVOLVEMENT PRESENTING WITH COMPLETE HEART BLOCK." Journal of the American College of Cardiology 81, no. 8 (2023): 3888. http://dx.doi.org/10.1016/s0735-1097(23)04332-2.

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14

Neu, Rachel, Melvin A. Leonard, Michelle L. Dehoorne, Samantha J. Scalia, Pramodini B. Kale-Pradhan, and Christopher A. Giuliano. "Impact of Pharmacist Involvement in Heart Failure Transition of Care." Annals of Pharmacotherapy 54, no. 3 (2019): 239–46. http://dx.doi.org/10.1177/1060028019882685.

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Background: Heart failure (HF) transition of care (TOC) programs may improve continuity of care and coordination and decrease hospital readmissions. Objective: This study evaluated the impact of pharmacy-led HF TOC on HF readmission rate. Methods: This was a single-center, pre-post quasi-experimental study. Pharmacy TOC comprised admission and discharge medication reconciliations and patient education. Patients were included if they had a primary HF diagnosis. Patients were excluded if they were admitted for a non-HF diagnosis, admitted for <24 hours, had a stage IV cancer or dementia diagn
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15

Dorobantu, Lucian Florin, Ovidiu Stiru, Anca Prodea, et al. "Unique Case of Primary Malignant Fibrous Histiocytoma of the Right Ventricle with Moderator Band Involvement." Heart Surgery Forum 14, no. 4 (2011): 245. http://dx.doi.org/10.1532/hsf98.20101154.

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Malignant primary tumors of the heart are very rare and in most cases are located in the left side of the heart, but involvement of the moderator band of the right heart has not yet been described in the literature. We report the case of a 22-year-old woman who presented after an episode of transient sudden loss of consciousness. The transthoracic echocardiography (TTE) and transesophageal echocardiography evaluations showed an echogenic mass that originated in the right ventricle and protruded into the tricuspid valve during systole. While operating on the patient, we found a sessile tumor th
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16

Praena-Segovia, J., A. Sanchez-Gastaldo, M. Bernabeu-Wittel, R. Ocete-Pérez, R. Ávila-Polo, and M. L. Martino. "Primary Systemic Amyloidosis and High Levels of Angiotensin-Converting Enzyme: Two Case Reports." Case Reports in Cardiology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/976379.

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Infiltrative heart diseases are caused by a heterogeneous group of disorders; amyloidosis and sarcoidosis are two frequent causes of myocardial infiltration, which differ in clinical and biological outcome and treatment issues. The presence of high levels of angiotensin-converting enzyme (ACE) in a patient with infiltrative heart disease may increase suspicion of sarcoidosis. Nevertheless, no mention about increased ACE levels in extracerebral primary systemic amyloidosis is available. We present two cases of primary systemic amyloidosis, which are cardiac involvement and elevated ACE levels.
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17

Demko, I. V., L. I. Pelinovskaya, V. A. Mosina, et al. "CASE OF PRIMARY AMYLOIDOSIS WITH INVOLVEMENT OF THE HEART AND PERICARDIUM IN CARDIOLOGY PRACTICE." Russian Journal of Cardiology, no. 2 (January 1, 2017): 103–5. http://dx.doi.org/10.15829/1560-4071-2017-2-103-105.

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18

Kholopov, L. S., N. B. Gubegrits, O. A. Dyadyk, Yu E. Chirkov, and Yu V. Tsohoyeva. "A Case of Primary Amyloidosis Involving Liver, Stomach, Intestines, and Heart without Evident Kidney Involvement." Russian Journal of Gastroenterology, Hepatology, Coloproctology 31, no. 6 (2022): 47–55. http://dx.doi.org/10.22416/1382-4376-2021-31-6-47-55.

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Aim. Systemic amyloidosis caused by the synthesis and deposition of immunoglobulin light chains (AL amyloidosis) is a relatively rare disease that involves heart, kidneys, peripheral nervous system, gastrointestinal tract, and has a large number of various clinical manifestations. We present a clinical case of systemic AL amyloidosis with a predominant involvement of liver, stomach, intestines, and heart in a Caucasian female.Key points. A Caucasian woman presented to clinic with severe general weakness, abdominal pain, diarrhea, sudden weight loss, and palpitation. Initial examination reveale
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19

Ainscough, S., AM Power, and AN Brown. "Mantle cell lymphoma: primary oral presentation." Annals of The Royal College of Surgeons of England 99, no. 1 (2017): e13-e14. http://dx.doi.org/10.1308/rcsann.2016.0267.

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Mantle-cell lymphoma is an uncommon lymphoid malignancy of B-cells. It is often aggressive and prognosis is poor. A 69-year-old gentleman with a history of ischaemic heart disease was referred from primary care with a painless right floor of mouth swelling that had been present for 1 month. He otherwise completely asymptomatic. Incisional biopsy of the lesion was undertaken and marker studies demonstrated mantle cell lymphoma. Positron emission tomography–computed tomography and bone marrow biopsy showed widespread but low volume involvement. The patient was referred to the haematology multidi
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20

de la Fuente, Pablo, Kapil Rajwani, Iñigo Sistiaga, and Jose Pedro Lavrador. "Surgery on a Primary Cranial Vault Lymphoma." Neuro-Oncology 24, Supplement_4 (2022): iv15. http://dx.doi.org/10.1093/neuonc/noac200.065.

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Abstract AIMS Unique cranial involvement in Lymphomas is extraordinary and when it occurs, it is usually accompanied by systemic involvement. The role of the surgery in these cases is still unclear. METHOD Case report of a 72-year-old female with a primary cranial vault lymphoma with primary surgical management at time of recurrence. RESULTS 72-year-old female, with a background of treated breast cancer and ischemic heart, presented with a right parieto-occipital lytic bone lesion with a soft tissue mass with a diagnosis of Non-Hodgkin’s Lymphoma Type B, compatible with follicular lymphoma, wi
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21

Buleu, Florina, Elena Sirbu, Alexandru Caraba, and Simona Dragan. "Heart Involvement in Inflammatory Rheumatic Diseases: A Systematic Literature Review." Medicina 55, no. 6 (2019): 249. http://dx.doi.org/10.3390/medicina55060249.

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Introduction: Patients with inflammatory rheumatic diseases have an increased risk of developing cardiovascular manifestations. The high risk of cardiovascular pathology in these patients is not only due to traditional cardiovascular risk factors (age, gender, family history, smoking, sedentary lifestyle, cholesterol), but also to chronic inflammation and autoimmunity. Aim: In this review, we present the mechanisms of cardiovascular comorbidities associated with inflammatory rheumatic diseases, as they have recently been reported by different authors, grouped in electrical abnormalities, valvu
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22

Park, Joon Young, Joo-Young Na, Young-Il Park, Seon Jung Jang, and Yong-Han Jung. "Cardiac Amyloidosis in Autopsy Case of Sudden Unexpected Death." Korean Journal of Legal Medicine 47, no. 1 (2023): 14–20. http://dx.doi.org/10.7580/kjlm.2023.47.1.14.

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A 78-year-old woman with a medical history of hypertension and diabetes mellitus who underwent surgery for lumbar stenosis died of sudden cardiac arrest two days after the operation. An autopsy was performed; however, the cause of death was not identified macroscopically. Congo red staining detected amyloid deposits in the systemic organs, including the heart, lungs, liver, thyroid, and kidney. Immunohistochemical staining revealed an immunoglobulin lambda light chain, which can cause the primary form of systemic amyloidosis. The prognosis of patients with systemic amyloidosis is directly asso
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23

Michail, Michalis, Efstathios Kastritis, Sossana Delimpassi, et al. "Clinical Characteristics and Outcome of Primary AL Amyloidosis in Greece." Blood 110, no. 11 (2007): 4729. http://dx.doi.org/10.1182/blood.v110.11.4729.4729.

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Abstract Introduction: Primary systemic amyloidosis (AL) is a clonal plasma cells disorder characterized by deposition of amyloid fibrils derived from abnormal light chains, leading to multiorgan involvement and failure. There is no information regarding the clinical, laboratory, treatment characteristics and outcome of such patients in Greece. We performed a retrospective analysis in order to clarify these issues. Patients and Methods: Diagnosis of primary AL amyloidosis was based on positive Congo red staining, immunohistochemistry and the presence of typical clinical and laboratory features
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24

Gorkova, N. B., L. M. Starykh, and L. E. Karpova. "A case of early pelvic-brachial progressive muscular dystrophy with severe heart involvement." Kazan medical journal 72, no. 2 (1991): 142–44. http://dx.doi.org/10.17816/kazmj106605.

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Progressive muscular dystrophies (PMD) are a group of hereditary diseases characterized by a primary dystrophic process in muscle tissue. The peculiarity and characteristics of cardiac disorders depend both on the nosological form with a characteristic muscle pathology for each of them, and on the stage, severity of the course of the disease and the mass of the affected muscles, and circulatory failure is less pronounced than damage to skeletal muscles.
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25

Parmar, Manpreet K., Mariam Alikhan, Vivien M. Hsu, and Amanda Borham. "Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis)." Case Reports in Rheumatology 2019 (January 16, 2019): 1–3. http://dx.doi.org/10.1155/2019/7609386.

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Granulomatosis with polyangiitis (GPA) is a rare ANCA-associated necrotizing granulomatous vasculitis affecting small- to medium-sized vessels. Common manifestations of this disease process affect the ear, nose, throat, upper and lower airways, and kidneys. Cardiac involvement has been reported in 6–44% of patients, primarily as coronary arteritis and pericarditis. A majority of case reports of pericardial effusions in patients with GPA identify patients having constrictive pericarditis secondary to uremia. We are presenting a case of hemorrhagic pericarditis in a patient with GPA in which the
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26

Zemtsovsky, E. V., E. G. Malev, and S. V. Reeva. "SYSTEMIC INVOLVEMENT OF CONNECTIVE TISSUE AND THE HEART AS IMPORTANT CHARACTERISTICS OF PRIMARY MITRAL VALVE PROLAPSE." Russian Journal of Cardiology, no. 9 (January 1, 2014): 54–60. http://dx.doi.org/10.15829/1560-4071-2014-9-54-60.

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27

Turcotte‐Gosselin, Frédéric, Pierre Yves Turgeon, Alena Ikic, et al. "Is heart transplantation a valuable option in patients with diffuse systemic sclerosis and primary cardiac involvement?" Clinical Case Reports 8, no. 1 (2019): 137–41. http://dx.doi.org/10.1002/ccr3.2600.

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28

Melissaropoulos, Konstantinos, Dimitrios Bogdanos, Theodoros Dimitroulas, Lazaros I. Sakkas, George D. Kitas, and Dimitrios Daoussis. "Primary Sjögren’s Syndrome and Cardiovascular Disease." Current Vascular Pharmacology 18, no. 5 (2020): 447–54. http://dx.doi.org/10.2174/1570161118666200129125320.

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Sjögren’s syndrome is a rheumatic autoimmune disease that primarily affects middle-aged women and runs a slowly progressing course with sicca symptoms being the prevalent manifestation. Premature atherosclerosis and increased cardiovascular (CV) morbidity and mortality are frequently encountered in rheumatic diseases characterized by significant systemic inflammation, such as the inflammatory arthritides, systemic vasculitides and systemic lupus erythematosus. In the same context, chronic inflammation and immune aberrations underlying Sjögren’s syndrome are also reported to be associated with
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29

Kim, Eunsook, Jung-Hoon Cho, Woo Sang Jung, Sanghoon Lee, and Sok Cheon Pak. "Effect of Acupuncture on Heart Rate Variability in Primary Dysmenorrheic Women." American Journal of Chinese Medicine 39, no. 02 (2011): 243–49. http://dx.doi.org/10.1142/s0192415x11008786.

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Primary dysmenorrhea is a common gynecological complaint among young women that is related to an autonomic nervous system (ANS) disturbance. Acupuncture is one of several therapeutic approaches for primary dysmenorrhea, since it can modulate ANS function. The heart rate variability (HRV) parameters such as high frequency (HF), low frequency (LF) and LF/HF ratio are generally accepted tools to assess ANS activity. The purpose of this study was to investigate the effects of acupuncture applied at Hegu (LI4) and Sanyinjiao (SP6) points on HRV of women with primary dysmenorrhea during the late lut
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30

Soulaidopoulos, Stergios, Anastasia-Vasiliki Madenidou, Dimitrios Daoussis, et al. "Cardiovascular Disease in the Systemic Vasculitides." Current Vascular Pharmacology 18, no. 5 (2020): 463–72. http://dx.doi.org/10.2174/1570161118666200130093432.

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The vasculitides are a heterogeneous group of disorders, characterized by inflammatory cell infiltration and necrosis of blood vessels that cause vascular obstruction or aneurysm formation, affecting various organs such as lungs, kidneys, skin and joints. Cardiac involvement is commonly encountered in primary systemic vasculitis and it is associated with increased morbidity and mortality. Depending on the dominant pathophysiological mechanism, heart complications may manifest in different ways, including myocardial ischemia due to impaired micro- or macrovascular circulation, progressive heart
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31

Matsumoto, Renato Augusto Eidy Kiota, Juliana Hiraoka Catani, Mirela Liberato Campoy, Arthur Magalhães Oliveira, and Nestor de Barros. "Radiological findings of breast involvement in benign and malignant systemic diseases." Radiologia Brasileira 51, no. 5 (2018): 328–33. http://dx.doi.org/10.1590/0100-3984.2016.0125.

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Abstract Although the primary purpose of periodic mammograms in screening programs is to identify lesions suspected of being carcinomas, the findings are often related to systemic (benign or malignant) diseases, rather than breast cancer. Although the involvement of breast structures in systemic diseases is unusual, it can be included in the differential diagnosis of masses, skin changes, calcifications, asymmetry, and axillary lymphadenopathy. The main diagnostic entities that can be associated with such involvement are diabetes, chronic kidney disease, heart diseases, connective tissue disea
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32

Lalchandani, Arati, Taruni Lalchandani, Lubna Ahmad, and Devarth Lalchandani. "Prophylaxis of Rheumatic Fever/Rheumatic Heart Disease–Penicillin or Azithromycin, Who Wins?" Indian Journal of Cardiovascular Disease in Women - WINCARS 06, no. 01 (2021): 042–45. http://dx.doi.org/10.1055/s-0041-1728220.

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AbstractFor eradication of rheumatic fever (RF)/rheumatic heart disease (RHD), we must have a simplified diagnosis, and a treatment which is painless, easily available and safe; prophylaxis must be painless, safe, easily available, readily administered, and comprising a weekly oral single dose.Arati's regime for management of RF/RHD (ARMOR) consists of diagnosis and management of RF/RHD in today's context in a very easy and simplified way.ARMOR criteria: Arthritis or arthralgia with typical features suggestive of RF, carditis or cardiac involvement, typical of RF or RHD, and echocardiographic
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33

Goyal, Abhishek, Bishav Mohan, Kavita Saggar, and Gurpreet Singh Wander. "Primary haemochromatosis resulting in dilated cardiomyopathy arising out of mutation in HJV gene in Indian patients: a rare scenario." BMJ Case Reports 13, no. 9 (2020): e235650. http://dx.doi.org/10.1136/bcr-2020-235650.

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Primary haemochromatosis (PH) is a genetic disorder of iron metabolism with multiorgan involvement due to mutations in HFE or more rarely haemojuvelin (HJV) gene. Cardiac involvement results in dilated cardiomyopathy with reduced ejection fraction and progressive heart failure. PH is rarely reported from India and cardiomyopathy due to PH from HJV mutations is thought to be uncommon. We report two families with cardiomyopathy resulting from PH. Diagnosis was suspected on the basis of skin pigmentation, markedly elevated serum ferritin and transferring saturation. Genetic testing revealed a rar
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34

Humagain, S., R. Gurung, P. Pant, R. Koju, and TRS Bedi. "Pattern of Valvular Involvement and Demographic Features of Patients on Injection Benzathine Penicillin at Dhulikhel Hospital." Nepalese Heart Journal 9, no. 1 (2013): 16–19. http://dx.doi.org/10.3126/njh.v9i1.8342.

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Background Rheumatic heart disease (RHD) is the most common cardiovascular disease in children and young adults. Though declined and almost non-existent in developed nations, RHD is still one of the leading cause for premature death and disability in developing countries. Prevalence of RHD is high in both rural as well as urban area of Nepal. Present study is designed to look at the pattern of valvular involvement and demographic features in RHD. Methods 326 Patients indicated for inj. Benzathine penicillin were selected and echocardiograph performed to see the pattern of vavular involvement.
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35

Woudstra, Odilia I., Gerard J. J. Boink, Jacobus A. Winkelman, and Ron van Stralen. "A Rare Case of Primary Meningococcal Myopericarditis in a 71-Year-Old Male." Case Reports in Cardiology 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/1297869.

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We describe a case of primary meningococcal C pericarditis with myocardial involvement in a 71-year-old male that is thus far the oldest patient with isolated meningococcal pericardial disease and only the third patient with primary meningococcal myopericarditis described in English literature. Our patient was successfully treated by full sternotomy and surgical drainage combined with intravenous ceftriaxone. Mild symptoms unresponsive to anti-inflammatory treatment and leukocytosis may guide clinicians towards the correct diagnosis. It is important to recognize this cause of pericarditis as t
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36

Mastrobuoni, S., A. M. Dell'Aquila, and J. Herreros. "FatalToxoplasma gondiiDissemination in a Heart Transplant Recipient: Description of a Case." Case Reports in Transplantation 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/524279.

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A 45-year-old heart transplant recipient presented with fever, anorexia, asthenia, and lethargy. She had received heart transplantation only 5 weeks earlier for primary systemic amyloidosis with severe cardiac involvement. Serum sodium was low, and tacrolimus through level was high. Blood cultures and serology tests for infection were negative, and atypical pneumonia was suspected. Despite broad antibiotic, antiviral, and antifungal treatment, the patient clinical condition rapidly deteriorated and she died within three days of admission. Postmortem examination revealed a disseminatedToxoplasm
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37

Bruni, C., M. H. Buch, P. Seferovic, and M. Matucci-Cerinic. "AB0556 PRIMARY SYSTEMIC SCLEROSIS HEART INVOLVEMENT (PSSCHI): A SYSTEMATIC LITERATURE REVIEW (SLR), CONSENSUS-BASED DEFINITION AND PRELIMINARY VALIDATION." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1574.1–1575. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1964.

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Background:pSScHI may cause tissue, functional and conduction abnormalities with varied clinical manifestations. The absence of a clear definition of pSScHI impairs the significance and ability of focussed research, frequently not allowing the distinction between primary and secondary involvement.Objectives:We aimed to establish an expert consensus definition for pSScHI, to be used in clinical trials and everyday clinical practice, and to start its validation process.Methods:A SLR for cardiac manifestations and alterations in SSc was conducted using PubMed, Web of Science and Embase. Articles
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38

Feige, Katharina, Janine Rubbert, Annika Raupach, et al. "Cardioprotective Properties of Mannitol—Involvement of Mitochondrial Potassium Channels." International Journal of Molecular Sciences 22, no. 5 (2021): 2395. http://dx.doi.org/10.3390/ijms22052395.

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Cardiac preconditioning (PC) and postconditioning (PoC) are powerful measures against the consequences of myocardial ischemia and reperfusion (I/R) injury. Mannitol—a hyperosmolar solution—is clinically used for treatment of intracranial and intraocular pressure or promotion of diuresis in renal failure. Next to these clinical indications, different organ-protective properties—e.g., perioperative neuroprotection—are described. However, whether Mannitol also confers cardioprotection via a pre- and/or postconditioning stimulus, possibly reducing consequences of I/R injury, remains to be seen. Th
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39

Stamatelopoulos, Kimon, Marita Lyka, Christos Papamichail, et al. "Hemodynamic, Functional and Structural Markers of Vascular Involvement in Primary Systemic Light Chain (AL) Amyloidosis." Blood 124, no. 21 (2014): 2029. http://dx.doi.org/10.1182/blood.v124.21.2029.2029.

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Abstract Light chain (AL) amyloidosis is characterized by the extracellular deposition of clonal light chain-derived amyloid fibrils in various tissues. Kidneys and heart are most commonly affected; clinically non detectable deposits in other tissues may also result in significant dysfunction. Amyloid deposits within the wall of the arteries or direct toxicity of light chains may cause arterial dysfunction in patients with AL amyloidosis, with cardiovascular consequences. Endothelial dysfunction, subclinical atherosclerosis of the carotid arteries and stiffening of the arterial tree are common
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40

Benfaremo, D., G. Stronati, L. Manfredi, et al. "SAT0307 PROGRESSION OF SUBCLINICAL MYOCARDIAL INVOLVEMENT IN PATIENTS WITH SYSTEMIC SCLEROSIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1098.1–1099. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2824.

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Background:Systemic sclerosis (SSc) is a progressive autoimmune disease affecting the skin as well as internal organs, including the heart. A few studies have identified a subclinical heart involvement in patients with no pulmonary hypertension. Changes in myocardial deformation are consistent with the idea of SSc-related cardiomyopathy as a primary condition affecting the heart globally through microvascular dysfunction and subsequent myocardial fibrosis.Objectives:The aim of the present study is to describe the progression of myocardial deformation in patients with SSc and no overt cardiac d
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Sharma, Poonam, Urmila Shakya, Sunita KC, and Manish Shrestha. "Clinical Profile and Management in Children with Rheumatic Heart Disease in a Tertiary Cardiac Care Center of Nepal." Nepalese Heart Journal 13, no. 2 (2016): 33–36. http://dx.doi.org/10.3126/njh.v13i2.15562.

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Backgrounds and Aims: Rheumatic heart disease is the commonest acquired heart disease in children of developing world presenting earlier and with a more severe valvular lesion. This study was conducted to assess the clinical and demographic profile, pattern of valvular involvement and management modalities among children with rheumatic heart disease.Methods: This was a hospital-based observational study, performed at Shahid Gangalal National Heart Center where all children less than 15 years of age with confirmed echocardiographic diagnosis of rheumatic heart disease from June 2015 to May 2016
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Olivas-Chacon, Cristina I., Carola Mullins, Kevan Stewart, Nassim Akle, Jesus E. Calleros, and Luis R. Ramos-Duran. "Magnetic Resonance Imaging of Non-ischemic Cardiomyopathies: A Pictorial Essay." Journal of Clinical Imaging Science 5 (June 30, 2015): 37. http://dx.doi.org/10.4103/2156-7514.159564.

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Non-ischemic cardiomyopathies are defined as either primary or secondary diseases of the myocardium resulting in cardiac dysfunction. While primary cardiomyopathies are confined to the heart and can be genetic or acquired, secondary cardiomyopathies show involvement of the heart as a manifestation of an underlying systemic disease including metabolic, inflammatory, granulomatous, infectious, or autoimmune entities. Non-ischemic cardiomyopathies are currently classified as hypertrophic, dilated, restrictive, or unclassifiable, including left ventricular non-compaction. Cardiovascular Magnetic R
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Lipinski, M., D. Eagles, L. M. Fischer, L. Mielneczuk, and I. G. Stiell. "LO02: Heart failure and palliative care in the emergency department." CJEM 19, S1 (2017): S27—S28. http://dx.doi.org/10.1017/cem.2017.64.

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Introduction: Heart failure (HF) is a common ED presentation that is associated with significant morbidity and mortality. Despite recent evidence and recommendations for early palliative care (PC) involvement in these patients, they are still significantly under-served by PC services, often resulting in multiple ED visits. We sought to evaluate use of PC services in patients with HF presenting to the ED. Secondary objectives of the study were to investigate: 1) one year mortality, ED visits, and admissions; 2) application of a novel palliative care referral score. Methods: We conducted a healt
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Raat, Willem, Miek Smeets, Stefan Janssens, and Bert Vaes. "Impact of primary care involvement and setting on multidisciplinary heart failure management: a systematic review and meta‐analysis." ESC Heart Failure 8, no. 2 (2021): 802–18. http://dx.doi.org/10.1002/ehf2.13152.

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Toscano, G., A. Fabozzo, M. Fedrigo, A. Gambino, A. Angelini, and G. Gerosa. "Post-transplant Lymphoproliferative Disorders: A Rare Case of Primary Pericardial Involvement Epstein-Barr Virus-Correlated in Heart Transplantation." Transplantation Proceedings 47, no. 7 (2015): 2287–90. http://dx.doi.org/10.1016/j.transproceed.2015.04.085.

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Sampath Kumar, Arkalgud. "Surgical options in rheumatic heart disease: an Indian surgeon’s perspective." Asian Cardiovascular and Thoracic Annals 28, no. 7 (2019): 371–73. http://dx.doi.org/10.1177/0218492319884797.

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Rheumatic heart disease is the primary cause of valvular heart disease in India and other Southeast Asian countries. The disease is quite different from that seen in France, USA, and Australia. Poverty, malnutrition, and delayed referral affect the outcomes. Rheumatic heart disease can affect all four heart valves, mitral being the most common, aortic second, tricuspid next, and finally the pulmonary valve. The combinations of mitral and aortic, mitral and tricuspid, and all three valves are the next in frequency. Acute rheumatic fever usually manifests as quadrivalvular involvement. However,
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Severino, Paolo, Andrea D’Amato, Silvia Prosperi, et al. "Do the Current Guidelines for Heart Failure Diagnosis and Treatment Fit with Clinical Complexity?" Journal of Clinical Medicine 11, no. 3 (2022): 857. http://dx.doi.org/10.3390/jcm11030857.

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Heart failure (HF) is a clinical syndrome defined by specific symptoms and signs due to structural and/or functional heart abnormalities, which lead to inadequate cardiac output and/or increased intraventricular filling pressure. Importantly, HF becomes progressively a multisystemic disease. However, in August 2021, the European Society of Cardiology published the new Guidelines for the diagnosis and treatment of acute and chronic HF, according to which the left ventricular ejection fraction (LVEF) continues to represent the pivotal parameter for HF patients’ evaluation, risk stratification an
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Guimarães-Okamoto, Priscilla Tatiana Chalfun, Maria Claudia Lopes Da Silva, Julio Lopes Sequeira та ін. "Primary Diffuse Large B Cell Lymphoma in Kidney with Involvement of Central Nervous System and Heart in a Siamese Cat". Acta Scientiae Veterinariae 44, № 1 (2016): 4. http://dx.doi.org/10.22456/1679-9216.82945.

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Background: Lymphoma is the most common neoplasia in cats and usually happens in middle-aged males of European breeds, FeLV-positive test is also observed in 25% to 50% of these cases. The diagnostic of renal lymphoma is based on clinical signs, the diagnosis is based on clinical signs associated with additional tests. Histological an immunohistochemical evaluations allows the classifcation which can provide prognostic information. Central nervous system metastasis is frequently reported, but lingual and lung lobe extension were also reported. Here, we report a case of renal lymphoma with syst
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Rabadão, Tiago, Leonor Naia, Filipa Ferreira, et al. "Not Always (and Only) Heart Failure—A Case Report of Primary Pleural Lymphoma in an Elderly Patient." Clinics and Practice 11, no. 1 (2021): 32–36. http://dx.doi.org/10.3390/clinpract11010006.

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Pleural involvement in Non-Hodgkin Lymphoma (NHL) is well documented, but primary pleural lymphomas are extremely rare, occurring mostly in immunosuppressed patients or associated with chronic pleural inflammation. Nevertheless, the pathogenesis and therapeutic approaches to counteract primary pleural lymphomas are still matter of debate. The authors present the clinical case of an 81-year-old female with respiratory and constitutional symptoms. A valvular heart disease and bilateral pleural effusion were known. The study carried out showed a large right pleural effusion; the fluid analysis wa
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Bani Hani, Amjad, Mahmoud Abu-abeeleh, Murad M. Al Kharabsheh, and Lubaba Qabba'ah. "Libman-Sacks Endocarditis with Unusual Large Size Vegetation Involving the Mitral Valve." Heart Surgery Forum 19, no. 6 (2016): 294. http://dx.doi.org/10.1532/hsf.1612.

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Antiphospholipid syndrome (APS) is an autoimmune hypercoagulable disorder characterized by thrombophilia, vascular thrombosis, and recurrent abortions associated with persistent antiphospholipid antibodies. APS may exist in its primary form, or more commonly is found to be associated with variety of rheumatic disorders, such as systemic lupus erythematosus. Cardiac involvement is not an uncommon complication in primary antiphospholipid patients. Libman-Sacks lesions are typically small, sessile, and wart-like, varying in size from 1-4 mm. Here we present an unusual case of a 37 year-old pregna
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