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1

Machiya, Tichaona, Rosemary J. Burnett, Lucy Fernandes, et al. "Hepatitis B vaccination of healthcare workers at the Princess Marina Hospital, Botswana." International Health 7, no. 4 (2014): 256–61. http://dx.doi.org/10.1093/inthealth/ihu084.

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2

W Kassa, Mamo, Jack J Mkubwa, Jemal Z Shifa, and Tefera B Agizew. "Type of anaesthesia for caesarean section and failure rate in Princess Marina Hospital, Botswana’s largest referral hospital." African Health Sciences 20, no. 3 (2020): 1229–36. http://dx.doi.org/10.4314/ahs.v20i3.26.

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Background: Caesarean Section (CS) is a mode of delivery to decrease maternal and perinatal morbidity and mortality. We aimed to determine the type of anaesthesia used for CS among live-birth deliveries; and the failure rate of spinal anaesthesia (SA) in Princess Marina Referral Hospital, Botswana.
 Methods: Women who underwent CS from May-December 2017 were enrolled in the study. Data were recorded from anaesthesia charts and abstracted using Excel spreadsheet. We established the type of anaesthesia used, comparing the rate of elective versus emergency indications, and failure rate of SA
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3

Banda, Francis M., Kathleen M. Powis, Agnes B. Mokoka, et al. "Hearing Impairment Among Children Referred to a Public Audiology Clinic in Gaborone, Botswana." Global Pediatric Health 5 (January 1, 2018): 2333794X1877007. http://dx.doi.org/10.1177/2333794x18770079.

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Objective. To describe and quantify hearing impairment among children referred to the audiology clinic in Princess Marina Hospital, a public referral hospital in Botswana. Methods. In a retrospective case series, we reviewed medical records of children aged 10 years and younger whose hearing was assessed between January 2006 and December 2015 at the audiology clinic of Princess Marina Hospital in Gaborone, Botswana. Results. Of 622 children, 50% were male, and median age was 6.7 years (interquartile range = 5.0-8.3). Hearing impairment was diagnosed in 32% of clinic attendees, comprising senso
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4

Mudzikati, Lydia, and Angela Dramowski. "Neonatal septicaemia: prevalence and antimicrobial susceptibility patterns of common pathogens at Princess Marina Hospital, Botswana." Southern African Journal of Infectious Diseases 30, no. 3 (2015): 108–13. http://dx.doi.org/10.1080/23120053.2015.1074443.

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5

Twomey, Michele, Paul C. Mullan, Susan B. Torrey, Lee wallis, and Andrew Kestler. "The Princess Marina Hospital accident and emergency triage scale provides highly reliable triage acuity ratings." Emergency Medicine Journal 29, no. 8 (2011): 650–53. http://dx.doi.org/10.1136/emermed-2011-200503.

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6

Chandra, Amit, Paul Mullan, Ari Ho-Foster, et al. "Epidemiology of patients presenting to the emergency centre of Princess Marina Hospital in Gaborone, Botswana." African Journal of Emergency Medicine 4, no. 3 (2014): 109–14. http://dx.doi.org/10.1016/j.afjem.2013.12.004.

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7

Yeh, Pon-Hsiu, Eric Cioe, Aurelio Rodriguez, and Megan Cox. "Epidemiology of Poisoning Patients Presenting to the Emergency Center of Princess Marina Hospital in Gaborone, Botswana." Prehospital and Disaster Medicine 32, S1 (2017): S206—S207. http://dx.doi.org/10.1017/s1049023x17005398.

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8

Yeh, P. H., E. Cioe-Pena, A. Rodriguez, and M. Cox. "Epidemiology of Poisoning Patients Presenting to the Emergency Center of Princess Marina Hospital in Gaborone, Botswana." Annals of Global Health 83, no. 1 (2017): 30. http://dx.doi.org/10.1016/j.aogh.2017.03.064.

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9

Rwegerera, GM, M. Bayani, EK Taolo, and D. Habte. "The prevalence of chronic kidney disease and associated factors among patients admitted at princess marina hospital, Gaborone, Botswana." Nigerian Journal of Clinical Practice 20, no. 3 (2017): 313. http://dx.doi.org/10.4103/1119-3077.187335.

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10

Leba, Kabongo. "Understanding Mortality and Morbidity Meeting at Princess Marina Hospital: Case of Accident and Emergency Department (April 2014 to March 2015)." TEXILA INTERNATIONAL JOURNAL OF MEDICINE 4, no. 2 (2016): 9–22. http://dx.doi.org/10.21522/tijmd.2013.04.02.art003.

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11

Molefi, Mooketsi, Jose-Gaby Tshikuka, Tuduetso Leka Monagen, et al. "The Burden of HIV-Related Admissions and Mortality at Princess Marina Hospital, Botswana in 2000: A Pre-Combination Antiretroviral Therapy Era." World Journal of AIDS 07, no. 01 (2017): 67–75. http://dx.doi.org/10.4236/wja.2017.71007.

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12

Molefi, Tsholofelo. "Development of an Accident and Emergency Triage Mobile App Using Open Data Kit." Iproceedings 5, no. 1 (2019): e15248. http://dx.doi.org/10.2196/15248.

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Background The process of triaging is performed as an effective solution to balance limited resources against high patient volumes, based on an assessment of the patient’s medical condition and the application of an established patient categorization protocol. In Princess Marina Hospital (PMH), a national referral government hospital in the capital city of Botswana, the Princess Marina Hospital Accident and Emergency Centre Triage Scale (PATS) has been in use since 2010. Because the rules of these triage scales are very well defined, these protocols have been shown to be amenable to translatio
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13

Kaur, Sukhdeep, Ashwin Chandar, Tina M. Mayer, et al. "Evaluating the challenges of cancer care in Botswana: Chemotherapy utilization and stock outs." Journal of Clinical Oncology 37, no. 15_suppl (2019): e18309-e18309. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18309.

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e18309 Background: As a significant percentage of cancer deaths are occurring in low- and middle-income countries, there is an unmet need in facilitating cancer care delivery in these countries. Data on stock-outs and shortages of cancer medicines in Botswana have been reported as one of the roots hindering treatment and potentially increasing mortality, with at least 40% of essential drugs being out of stock for at least 30 days in 2015. A methodologic approach was published in 2018 to forecast chemotherapy (CT) volume, however, this was based on incidence and prevalence data, using multiple
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14

Offorjebe, Ogechukwu A., Adriane Wynn, Neo Moshashane, et al. "Partner notification and treatment for sexually transmitted infections among pregnant women in Gaborone, Botswana." International Journal of STD & AIDS 28, no. 12 (2017): 1184–89. http://dx.doi.org/10.1177/0956462417692455.

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Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) are sexually transmitted infections (STIs) associated with adverse birth outcomes. Untreated partners contribute to high rates of STI reinfection; thus, partner notification and treatment remain important components of STI care and control. A prospective cohort study was conducted among 300 pregnant women presenting to the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana who enrolled in an STI screening study. Following informed consent and sample collection for CT/NG/TV testing, participan
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15

Martei, Yehoda M., Surbhi Grover, Warren B. Bilker, et al. "Impact of Essential Medicine Stock Outs on Cancer Therapy Delivery in a Resource-Limited Setting." Journal of Global Oncology, no. 5 (December 2019): 1–11. http://dx.doi.org/10.1200/jgo.18.00230.

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PURPOSE Essential cancer medicine stock outs are occurring at an increasing frequency worldwide and represent a potential barrier to delivery of standard therapy in patients with cancer in low- and middle-income countries. The objective of this study was to measure the impact of cancer medicine stock outs on delivery of optimal therapy in Botswana. METHODS We conducted a retrospective analysis of patients with common solid tumor malignancies who received systemic cancer therapy in 2016 at Princess Marina Hospital, Gaborone, Botswana. Primary exposure was the duration of cancer medicine stock o
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16

Magalhães-Barbosa, Maria Clara, Jaqueline Rodrigues Robaina, Arnaldo Prata-Barbosa, and Claudia de Souza Lopes. "Reliability of triage systems for paediatric emergency care: a systematic review." Emergency Medicine Journal 36, no. 4 (2019): 231–38. http://dx.doi.org/10.1136/emermed-2018-207781.

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ObjectiveTo present a systematic review on the reliability of triage systems for paediatric emergency care.MethodsA search of MEDLINE, Cochrane Library, Latin American and Caribbean Health Sciences Literature, Scientific Electronic Library Online, Nursing Database Index and Spanish Health Sciences Bibliographic Index for articles in English, French, Portuguese or Spanish was conducted to identify reliability studies of five-level triage systems for patients aged 0–18 years published up to April 2018. Two reviewers performed study selection, data extraction and quality assessment as recommended
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17

Wynn, Adriane, Doreen Ramogola-Masire, Ponatshego Gaolebale, et al. "Prevalence and treatment outcomes of routine Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing during antenatal care, Gaborone, Botswana." Sexually Transmitted Infections 94, no. 3 (2017): 230–35. http://dx.doi.org/10.1136/sextrans-2017-053134.

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ObjectivesChlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) are curable, mostly asymptomatic, STIs that cause adverse maternal and perinatal outcomes. Most countries do not test for those infections during antenatal care. We implemented a CT, NG and TV testing and treatment programme in an antenatal clinic in Gaborone, Botswana.MethodsWe conducted a prospective study in the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana. We offered pregnant women who were 18 years or older and less than 35 weeks of gestation, CT, NG and TV testing using s
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18

Chandar, Ashwin, Sukhdeep Kaur, Tlotlo Bathethi Ralefala, et al. "Building international partnerships to improve global oncological care: Perspective from Rutgers-CINJ Global Oncology Fellowship Program." Journal of Clinical Oncology 37, no. 27_suppl (2019): 159. http://dx.doi.org/10.1200/jco.2019.37.27_suppl.159.

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159 Background: With cancer accounting for 1 in every 7 deaths worldwide and 60-70% of cancer deaths occurring in low- and middle-income countries, any advancement in cancer care should include understanding to alleviate structural inequalities that produce these global oncological disparities. Rutgers-Cancer Institute of New Jersey (R-CINJ) Oncology Fellowship program, through partnerships with Rutgers Global Health and University of Botswana (UB), established a global oncology program in 2018 to provide young oncologists in training with this educational opportunity. Aims included understand
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19

Anakwenze, Chidinma, Rohini Bhatia, William Rate, et al. "Factors Related to Advanced Stage of Cancer Presentation in Botswana." Journal of Global Oncology, no. 4 (December 2018): 1–9. http://dx.doi.org/10.1200/jgo.18.00129.

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Purpose Botswana, a country with a high prevalence of HIV, has an increasing incidence of cancer-related mortality in the post–antiretroviral therapy era. Despite universal access to free health care, the majority of Botswana patients with cancer present at advanced stages. This study was designed to explore the factors related to advanced-stage cancer presentation in Botswana. Methods Patients attending an oncology clinic between December 2015 and January 2017 at Princess Marina Hospital in Gaborone, Botswana, completed a questionnaire on sociodemographic and clinical factors as well as cance
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20

Chandar, Ashwin, Sukhdeep Kaur, Deborah Toppmeyer, et al. "Building international partnerships to improve global oncological care: Perspective from Rutgers-CINJ Global Oncology Fellowship Program." Journal of Clinical Oncology 37, no. 15_suppl (2019): e18161-e18161. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18161.

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e18161 Background: With cancer accounting for 1 in every 7 deaths worldwide and 60-70% of cancer deaths occurring in low- and middle-income countries, any advancement in cancer care should include understanding to alleviate structural inequalities that produce these global oncologic disparities. Rutgers-Cancer Institute of New Jersey (R-CINJ) Oncology Fellowship program, through partnerships with Rutgers Global Health and University of Botswana (UB), established a global oncology program in 2018 to provide young oncologists in training with this educational opportunity. Aims included understan
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21

Mokokwe, L., G. Maabane, D. Zambo, et al. "First Things First: Adopting a Holistic, Needs-Driven Approach to Improving the Quality of Routinely Collected Data." Journal of Global Oncology 4, Supplement 2 (2018): 155s. http://dx.doi.org/10.1200/jgo.18.68700.

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Background and context: Routine collection of quality oncology data remains underprioritized in resource limited settings. For breast cancer (BC) care at Princess Marina Hospital (PMH) in Botswana, this hampers its use for oncology program evaluation and clinical research. The Peo Data Acquisition Core (DAC), part of a consortium for planning of a noncommunicable diseases center for research excellence in Southern Africa, engaged relevant stakeholders and departments at PMH to establish health care worker driven processes that support sustained improvements in the quality of routinely collecte
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22

Westmoreland, Katherine D., Francis M. Banda, Andrew P. Steenhoff, Elizabeth D. Lowenthal, Erik Isaksson, and Bernhard A. Fassl. "A standardized low-cost peer role-playing training intervention improves medical student competency in communicating bad news to patients in Botswana." Palliative and Supportive Care 17, no. 1 (2018): 60–65. http://dx.doi.org/10.1017/s1478951518000627.

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AbstractObjectiveThe purpose of this study was to demonstrate effectiveness of an educational training workshop using role-playing to teach medical students in Botswana to deliver bad news.MethodA 3-hour small group workshop for University of Botswana medical students rotating at the Princess Marina Hospital in Gaborone was developed. The curriculum included an overview of communication basics and introduction of the validated (SPIKES) protocol for breaking bad news. Education strategies included didactic lecture, handouts, role-playing cases, and open forum discussion. Pre- and posttraining s
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23

Popli, Pallvi, Mansi R. Shah, Tlotlo B. Ralefala, et al. "Reducing Oncologic Disparities by Standardizing Cancer Care." JCO Global Oncology 6, Supplement_1 (2020): 64. http://dx.doi.org/10.1200/go.20.61000.

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PURPOSE Shortages in oncology-trained health care providers pose a major challenge in low- and middle-income countries (LMICs) and contribute to delays in the diagnosis and treatment of cancer. Presently, the sole oncologist in the public sector at Princess Marina Hospital, Botswana’s largest oncology referral center, is overextended, causing medical officers to be the primary providers for patients with cancer. Medical officers do not possess formal oncology training, which can potentially lead to imprecise management and suboptimal treatment. In addition, there is no standardized patient int
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Martei, Yehoda M., Surbhi Grover, Mohan Narasimhamurthy, et al. "Relative dose intensity and pathologic response rates in HIV-infected and HIV-uninfected breast cancer patients who received neoadjuvant chemotherapy." Journal of Clinical Oncology 38, no. 15_suppl (2020): e19140-e19140. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e19140.

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e19140 Background: HIV-infected (HIV+) breast cancer patients may have significantly worse survival compared to HIV-uninfected (HIV-). If so, identifying the underlying mechanism might lead to effective interventions to reduce the disparity. Relative dose intensity (RDI) < 0.85 has been associated with worse survival outcomes in non-metastatic breast cancer patients. We aimed to determine if RDI of chemotherapy and pathologic complete response (pCR) rates were lower for HIV+ patients who received neoadjuvant chemotherapy (NAC) compared with HIV-. Methods: We conducted a prospective cohort s
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Shah, Sidrah, Barati Monare, Sandra Urusaro, et al. "Usability and Effectiveness of a Smartphone Application for Tracking Oncology Patients in Gaborone, Botswana." Journal of Global Oncology 5, Supplement_1 (2019): 11. http://dx.doi.org/10.1200/jgo.19.20000.

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PURPOSE Most cancer diagnoses are expected to be in low- and middle-income countries (LMICs) by 2025, and 65% of cancer deaths occur in LMICs. Treatment adherence and patient monitoring are essential to cancer care but are often not possible in LMICs. OP Care, a smartphone application developed to fill this gap, stores medical records virtually and texts appointment reminders to patients. This study assessed its usability and effectiveness. METHODS OP Care was piloted at Princess Marina Hospital in Gaborone, Botswana. The study was a cross-sectional study using surveys. All providers using the
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Davey, Sonya, Surbhi Grover, Dipho Irene I. Setlhako, et al. "Prescription patterns and associated cost during periods of cancer drug stockouts in a resource-limited setting." Journal of Clinical Oncology 37, no. 15_suppl (2019): e18129-e18129. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18129.

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e18129 Background: Cancer drug stockouts occur at high frequencies globally, however their clinical effects are understudied in sub-Saharan Africa (SSA). We aim to describe prescription patterns and cost of systemic chemotherapy in cancer patients in Botswana during periods of stockout. Methods: Using a retrospective cohort study of the ten most common solid tumor malignancies treated with systemic chemotherapy at Princess Marina Hospital (PMH), Gaborone in 2016, we conducted a subset analysis of suboptimal events, defined as a cycle with ≥ 7 days delay or therapy switch from initiated guideli
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Rubagumya, F., L. Greenberg, A. Manirakiza, et al. "Establishing a Childhood Cancer Survivorship Program in Rwanda." Journal of Global Oncology 4, Supplement 2 (2018): 87s. http://dx.doi.org/10.1200/jgo.18.30400.

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Background: Over 80% of children diagnosed with cancer survive in high-income countries (HICs). While the survival rate remains poor in low- and middle-income countries (LMICs) such as Rwanda, a growing number of children with cancer are surviving to adulthood. These children and young adults will face an increased risk of secondary cancers and late complications from their curative treatment. Cancer centers in HICs have established Long Term Survivorship (LTS) programs to cater for childhood cancer survivors and to capture these complications and/or recurrences at an early stage. They also ad
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Grover, Surbhi, Sidrah Shah, Rohini Bhatia, et al. "Development and Usability of a Smartphone Application for Tracking Oncology Patients in Gaborone, Botswana." Methods of Information in Medicine 59, no. 01 (2020): 031–40. http://dx.doi.org/10.1055/s-0040-1713129.

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Abstract Background The majority of new cancer cases are expected to be diagnosed in low- and middle-income countries (LMICs) by 2025, and 65% of cancer deaths currently occur in LMICs. Treatment adherence, patient monitoring, and follow-up are essential to cancer care but are often not possible in these settings. Out Patient (OP) Care, a smartphone application (app) developed to fill this gap, texts appointment reminders to patients and electronically stores medical records confidentially. Objectives This study aims to present the development of this app and evaluate its usability and feasibi
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Martei, Y., S. Grover, W. Bilker, et al. "Impact of Chemotherapy Stock-Out on Standard Therapy Delivery Among Cancer Patients in Botswana." Journal of Global Oncology 4, Supplement 2 (2018): 90s. http://dx.doi.org/10.1200/jgo.18.30500.

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Background: Cancer drug shortages represent a complex global issue with potentially adverse survival outcomes. Up to 98% of oncologists and pharmacists surveyed in North America reported at least 1 drug shortage in the prior year and 66% reported at least one patient who had clinical care impacted by the shortage. In low- and middle-income countries (LMICs), these shortages are even more frequent. No studies to our knowledge have evaluated the impact of chemotherapy stock-out on receipt of standard cancer therapy in LMICs. Aim: Quantify the association between the duration of chemotherapy stoc
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Nkhwalume, Ludo, and Yohana Mashalla. "Maternal mortality trends at the Princess Marina and Nyangabwe referral hospitals in Botswana." African Health Sciences 19, no. 2 (2019): 1833. http://dx.doi.org/10.4314/ahs.v19i2.5.

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31

Senkāne, Olga. "INTERPRETATION OF THE IMAGE OF LATGALE IN THE CULTURE DISCOURSE." Via Latgalica, no. 5 (December 31, 2013): 96. http://dx.doi.org/10.17770/latg2013.5.1647.

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There are cultures that focus on their origins, while there are also cultures oriented towards their destination: the former perceive the time in mythical manner – in its cycles, while the latter perceive it historically– in its linearity. The movement in the time-space continuum and its specifi cs in different cultures is provided by the desire either to pay more attention to the truth already known (the old texts) or to discover new one (new texts). The culture of Latgale is characterised by the prevalence of the old, constant texts or the traditional coding, as attested by persistent invoki
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32

Manwana, ME, GG Mokone, M. Kebaetse, and T. Young. "Epidemiology of traumatic orthopaedic injuries at Princess Marina Hospital, Botswana." SA Orthopaedic Journal 17, no. 1 (2018). http://dx.doi.org/10.17159/2309-8309/2018/v17n1a6.

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33

Molefi, Mooketsi. "Princess Marina Hospital HIV rates:Interrupted time series analysis for policy review." Online Journal of Public Health Informatics 10, no. 1 (2018). http://dx.doi.org/10.5210/ojphi.v10i1.8602.

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ObjectiveWe aimed to assess the effect of the amended Public Health act of 2013 on facility-based HIV testing in Princess Marina Hospital.IntroductionHIV testing remains the mainstay of optimal HIV care and is pivotal to control and prevention of the disease, however efforts to attain optimal testing levels have been undermined by low HIV testing especially in developing countries. Botswana in response, amended its Public Health Act in September 2013 but the effect of this action on facility based HIV testing rates has not been evaluated.MethodsWe carried out an effect assessment using interru
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Tsima, Billy M., Farai D. Madzimbamuto, and Bob Mash. "Use of oxytocin during Caesarean section at Princess Marina Hospital, Botswana: An audit of clinical practice." African Journal of Primary Health Care & Family Medicine 5, no. 1 (2013). http://dx.doi.org/10.4102/phcfm.v5i1.418.

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Background: Oxytocin is widely used for the prevention of postpartum haemorrhage. In the setting of Caesarean section (CS), the dosage and mode of administrating oxytocin differs according to different guidelines. Inappropriate oxytocin doses have been identified as contributory to some cases of maternal deaths. The main aim of this study was to audit the current standard of clinical practice with regard to the use of oxytocin during CS at a referral hospital in Botswana.Methods: A clinical audit of pregnant women having CS and given oxytocin at the time of the operation was conducted over a p
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Mbuka-Ongona, Deogratias, and John M. Tumbo. "Knowledge about breast cancer and reasons for late presentation by cancer patients seen at Princess Marina Hospital, Gaborone, Botswana." African Journal of Primary Health Care & Family Medicine 5, no. 1 (2013). http://dx.doi.org/10.4102/phcfm.v5i1.465.

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Introduction: In Botswana, breast cancer, the second most common malignancy amongst women, is often diagnosed late, with 90% of patients presenting at advanced stages at Princess Marina Hospital (PMH) Gaborone, the only referral hospital with an operational oncology department. The reasons for this late presentation have not been studied. Determination of these reasons is critical for the formulation of strategies to reduce morbidity and mortality from breast cancer in Botswana. The aim of this study was to explore existing knowledge about breast cancer and the reasons for late presentation am
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"The meeting of the Autism Special Interest Group held on 29 May 2002 at Princess Marina Hospital, Northampton." Nutrition & Food Science 32, no. 6 (2002). http://dx.doi.org/10.1108/nfs.2002.01732fab.003.

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37

Bareki, Peter, and Tenego Tenego. "Assessment of knowledge, attitudes and practices of HIV post exposure prophylaxis among the doctors and nurses in Princess Marina Hospital, Gaborone: a cross-sectional study." Pan African Medical Journal 30 (2018). http://dx.doi.org/10.11604/pamj.2018.30.233.10556.

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38

Bhebhe, Lynnette, Motswedi Anderson, Sajini Souda, et al. "Molecular characterization of hepatitis C virus in liver disease patients in Botswana: a retrospective cross-sectional study." BMC Infectious Diseases 19, no. 1 (2019). http://dx.doi.org/10.1186/s12879-019-4514-1.

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Abstract Background Hepatitis C virus (HCV) infection is a major cause of chronic liver disease globally. Direct acting antivirals (DAAs) have proven effective in curing HCV. However, the current standard of care (SOC) in Botswana remains PEGylated interferon-α (IFN-α) with ribavirin. Several mutations have been reported to confer resistance to interferon-based treatments. Therefore, there is a need to determine HCV genotypes in Botswana, as these data will guide new treatment guidelines and understanding of HCV epidemiology in Botswana. Methods This was a retrospective cross-sectional pilot s
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