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1

Stoytcheva-Horissian, Biliana V. "Acting in comedy : an examination of performance principles and techniques /." view abstract or download file of text, 2002. http://wwwlib.umi.com/cr/uoregon/fullcit?p3055716.

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Thesis (Ph. D.)--University of Oregon, 2002.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 194-197). Also available for download via the World Wide Web; free to University of Oregon users.
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Hagman, Gustav. "Acting Against Principles : How the violation of conversation rules in dialoguecreates a clever TV character." Thesis, Högskolan Väst, Avd för utbildningsvetenskap och språk, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-6836.

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This paper studies the use of violations of conversation principles in the written dialogue of Tyrion Lannister in Game of Thrones. The aim is to establish if and how these violations aid in making him seem clever. The character's dialogues are matched against three theoretical principles: Politeness Theory, The Cooperative Principle and Turn-taking Principles. The findings suggest that by breaking basic principles of conversation, Tyrion provides entertaining dialogue and manages to create unexpected solutions to different threatening situations. Results show an even distribution of strategic
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Hamner, Matthew. "THE LARAMIE PROJECT: THE SEARCH FOR A PERSONAL ACTING METHOD VIA THE PRINCIPLES OF CONSTANTIN STANISLAVKSI." Master's thesis, University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3796.

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Constantin Stanislavski developed a method for actors in bringing to life characters for the stage. Even though Stanislavski developed his theories in response to the stage climate of the late nineteenth and early twentieth centuries, many of his ideas remain relevant today. In this study, parts of his system were applied to the roles performed in Mois&eacute;s Kaufman's The Laramie Project. Those roles were Mois&eacute;s Kaufman, Jonas Slonaker, Doug Laws, Anonymous, Detective Rob Debree, Governor Jim Geringer, Reverend Fred Phelps and Dennis Shepard. The purpose of this exploration was to cr
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COREY, FREDERICK CHARLES. "PRINCIPLES FOR THE USE OF STYLIZED MOVEMENT DURING THE INTERPRETATION AND PERFORMANCE OF LITERATURE BASED ON MARTHA GRAHAM'S USE OF CLASSICAL TRAGEDY IN MODERN DANCE." Diss., The University of Arizona, 1987. http://hdl.handle.net/10150/184153.

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The interpretation and performance of literature is a theatre art in which literary texts are transformed into staged productions. Novelists, poets, playwrights, and essayists use the symbols of written language to create an imagined world for their readers; interpretative performers present their audiences with this world through symbols of both speech and movement. Hence the interpretation and performance of literature incorporates a wide range of literary and performance theory. Unfortunately, little is known about how literary texts can be communicated through symbolic movement. The purpos
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Trivette, Carol M. "Principles of Adult Learning in Action." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/4456.

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Come join the Military Families Learning Network Early Intervention team on Weds. March 30 from 12:30-1:30 ET for an interactive discussion related to the webinar held on Mar. 17. We want to hear your thoughts, opinions, and experiences related to the Key Points Carol Trivette, PhD shared during the webinar and how you've applied these points recently in your own practices. Were you not able to participate in the webinar on the 17th? No worries! We'd still love to hear from you! Come share your expertise and learn from others during this interactive forum.
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Barra, Jérôme. "Intérêts des paramètres de solubilité et des énergies de surface dans la formulation des formes pharmaceutiques solides." Lyon 1, 1999. http://www.theses.fr/1999LYO1T177.

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Mantke, Wolfgang Johann. "Picture independent quantum action principle." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/29850.

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8

Pfäffle, Frank, and Christoph A. Stephan. "The Holst action by the spectral action principle." Universität Potsdam, 2012. http://opus.kobv.de/ubp/volltexte/2012/6003/.

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We investigate the Holst action for closed Riemannian 4-manifolds with orthogonal connections. For connections whose torsion has zero Cartan type component we show that the Holst action can be recovered from the heat asymptotics for the natural Dirac operator acting on left-handed spinor fields.
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Lima, Elaine Cardim de. "A singularidade vocal na composição da atriz: notações sobre um percurso." Escola de Teatro, 2011. http://repositorio.ufba.br/ri/handle/ri/27106.

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Submitted by Glauber Assunção Moreira (glauber.a.moreira@gmail.com) on 2018-08-24T15:39:04Z No. of bitstreams: 1 dissertação para impressão.pdf: 1190765 bytes, checksum: caed78b341b81739d8894144e3d5ad89 (MD5)<br>Approved for entry into archive by Marly Santos (marly@ufba.br) on 2018-08-27T20:01:20Z (GMT) No. of bitstreams: 1 dissertação para impressão.pdf: 1190765 bytes, checksum: caed78b341b81739d8894144e3d5ad89 (MD5)<br>Made available in DSpace on 2018-08-27T20:01:20Z (GMT). No. of bitstreams: 1 dissertação para impressão.pdf: 1190765 bytes, checksum: caed78b341b81739d8894144e3d5ad89 (MD
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Zhu, Min. "CNS active principles from selected Chinese medicinal plants." Thesis, University College London (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339881.

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Bleicher, Walter Philip [Verfasser], Andreas [Akademischer Betreuer] Bausch, Andreas [Gutachter] Bausch, and Zeynep [Gutachter] Ökten. "Molecular principles governing the organization of active actin networks / Walter Philip Bleicher ; Gutachter: Andreas Bausch, Zeynep Ökten ; Betreuer: Andreas Bausch." München : Universitätsbibliothek der TU München, 2021. http://d-nb.info/1228073252/34.

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12

Puech, Sébastien. "Le tragique de l'action humanitaire." Thesis, Reims, 2020. http://www.theses.fr/2020REIML010.

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Ce travail cherche à montrer comment la philosophie peut éclairer la pratique de l’action humanitaire, qui soulève sur le terrain une multitude de problématiques, ayant une portée philosophique (souffrances, politique, altruisme, don, bien, mal, espoir…). L’acteur humanitaire n’est pas préparé à affronter les situations dramatiques et complexes du terrain, le cadre normatif de l’action humanitaire et les principes humanitaires n’étant pas suffisants. Nous présentons une nouvelle lecture de l’action humanitaire, notamment par sa dimension profondément tragique, qui résulte de son échec insurmon
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Segret, Léa. "Traitement pré récolte en vue de développer des opérations culturales permettant d'optimiser la teneur en principes actifs de plants de ginseng." Thesis, Toulouse, INPT, 2020. http://www.theses.fr/2020INPT0003.

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France ginseng est une jeune entreprise qui cultive un ginseng "Made in France" de façon pérenne et rentable en France. Cette entreprise a développé un concept innovant de production de plante médicinale. En vue d'accélérer son développement et d'optimiser ses connaissances et ses techniques, un ambitieux programme de recherche et développement est lancé. Les objectifs du projet proposé porteront sur l'identification de facteurs agronomiques favorisant l'accumulation des ginsénosides et la qualité du produit obtenu. Plus précisément, il s'agira de définir et justifier via la physiologie de la
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Richardson, Sandra. "HEALTHCARE INFORMATION SYSTEMS:DESIGN THEORY, PRINCIPLES AND APPLICATION." Doctoral diss., University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3182.

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Healthcare information systems (HISs), as a class of systems, are not currently addressed in the MIS literature. This is in spite of a sharp increase in use over the past few years, and the uniquely qualified role that MIS has in the development of, impact and general understanding of HISs. In this project the design science paradigm frames the development of a set of design principles derived from the synthesis of the design literature, ethics literature, and professional guidelines, from both the medical and computing professions. The resulting principles are offered to address the design of
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Troncoso, Maria Isabel. "Le principe de précaution et la responsabilité civile." Thesis, Paris 2, 2016. http://www.theses.fr/2016PA020030.

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Les textes du Code civil relatifs à la responsabilité délictuelle ont peu évolué depuis 1804. En dépit de la cristallisation de la loi, cette matière a constitué un laboratoire privilégié de création jurisprudentielle. La Cour de cassation a, en effet, œuvré dans le sens de l’adaptation de la responsabilité civile à l’évolution des besoins de la société. La responsabilité du fait des choses inanimées ou encore les dommages causés par les accidents de la circulation sont autant de constructions prétoriennes audacieuses.Ce travail de recherche a pour objet d’analyser la capacité créative prétori
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Maxwell, Nicholas Elliott, and nmaxwel1@bigpond net au. "Black Comedy and the Principles of Screenwriting/The Actions." RMIT University. Creative Media, 2008. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20081212.123034.

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This exegesis will aim to research and analyse the conventions of writing a black comedy in a feature film script. As a screenwriter with a particular interest in black comedy, my aim is to explore the technical structures of black comedy in order to facilitate the writing of a tragicomic screenplay. We will attempt to define the components of black comedy and survey its origin in theatre and literature. The exegesis will aim to explore what components comprise the middle ground between drama and humour and position it in relation to the classical genres of tragedy and comedy. The ex
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Capdepuy, P. "Informational principles of perception-action loops and collective behaviours." Thesis, University of Hertfordshire, 2011. http://hdl.handle.net/2299/5199.

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Living beings, robotic and software artefacts can all be seen as agents acting and perceiving within an environment. When observed under that perspective, a new concept is accessible: information in the sense of Shannon. It has long been known that information and control are interrelated concepts. However it is only recently that this perspective has been better understood and used in order to study cognition. In this thesis, we build upon such an information-theoretic perspective and add some biologically motivated assumptions. They introduce various constraints on the capture, the processin
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Rolle, Drew G. "Affirmative action and a principle of colorblindness." Honors in the Major Thesis, University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1316.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.<br>Bachelors<br>Sciences<br>Political Science
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Johansen, Bianca. "Potentiel antimicrobien de principes actifs d’origine naturelle." Thesis, Université de Lorraine, 2017. http://www.theses.fr/2017LORR0242.

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Le développement de principe actif à partir de ressources naturelles pourrait être un moyen pour développer de nouvelles alternatives aux antibiotiques. L’huile essentielle d’arbre à thé est reconnue pour ses nombreuses propriétés et son activité antimicrobienne à spectre large, mais aussi pour sa toxicité et sa forte teneur en allergènes liée à sa composition en monoterpènes. Dans cette étude, nous cherchons de nouveaux principes actifs naturels issus de l’huile essentielle d’arbre à thé, qui auraient une activité antimicrobienne équivalente mais une toxicité et un pouvoir allergène réduit. D
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Crossley, Michael James. "An action principle for dissipative fluid dynamics." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/103242.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Physics, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 193-199).<br>Fluid dynamics is the universal theory of low-energy excitations around equilibrium states, governing the physics of long-lived modes associated with conserved charges. Historically, fluid dynamics has been formulated at the level of equations of motion, in terms of a local fluid velocity and thermodynamic quantities. In this thesis, we describe a new formulation of fluid dynamics in terms of a path integral, whi
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Demeulenaere, Pierre. "Enquête sur les principes des actions économiques." Paris 4, 1994. http://www.theses.fr/1994PA040009.

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Le but de ce travail est d'étudier les fondements conceptuels de la description des actions économiques. Cette recherche passe par un effort de clarification de concepts flous comme ceux d'économie, de rationalité économique, d'utilité, de valeur, de choix etc. . . La méthode de la recherche est de s'appuyer sur l'étude d'auteurs importants pour le sujet, qu'ils soient anciens ou contemporains comme Hume, Smith, Mill, Cournot, Weber, Keynes, Coleman. La méthode de l'investigation appartient à la tradition de l'individualisme méthodologique, et s'inspire notamment de l'oeuvre de Raymond Boudon<
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Rahte, Sinikka. "Investigating the mode of action and characterisation of active principles : a Salvia officinalis tincture for the amelioration of hot flushes." Thesis, University College London (University of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540313.

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Scane, Timothy M. N. "An investigation of the pharmacologically-active principles in amniotic fluid." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/38154.

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SADE, MARTIN CHARLES. "VARIATIONAL PRINCIPLES FOR FIELD VARIABLES SUBJECT TO GROUP ACTIONS (GAUGE)." Diss., The University of Arizona, 1985. http://hdl.handle.net/10150/188075.

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This dissertation is concerned with variational problems whose field variables are functions on a product manifold M x G of two manifolds M and G. These field variables transform as type (0,1) tensor fields on M and are denoted by ψ(h)ᵅ (h = 1, ..., n = dim M, α = 1, ..., r = dim G). The dependence of ψ(h)ᵅ on the coordinates of G is given by a generalized gauge transformation that depends on a local map h:M → G. The requirement that a Lagrangian that is defined in terms of these field variables be independent of the coordinates of G and the choice of the map h endows G with a local Lie group
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Pfäffle, Frank, and Christoph A. Stephan. "On gravity, torsion and the spectral action principle." Universität Potsdam, 2012. http://opus.kobv.de/ubp/volltexte/2012/5998/.

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We consider compact Riemannian spin manifolds without boundary equipped with orthogonal connections. We investigate the induced Dirac operators and the associated commutative spectral triples. In case of dimension four and totally anti-symmetric torsion we compute the Chamseddine-Connes spectral action, deduce the equations of motions and discuss critical points.
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Chabre, Yoann. "Matériaux dendritiques pour la délivrance de principes actifs." Nice, 2006. http://www.theses.fr/2006NICE4070.

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Ce travail porte sur la synthèse et la caractérisation de prodrogues dendritiques pour le relâchement de principes actifs destinés à des fins thérapeutiques dans le domaine biomédical et ophtalmologique. Les dendrimères se définissent comme une classe de macromolécules polyfonctionnelles monodisperses, monomoléculaires et hautement branchées, formées de cavités et d’unités répétitives. Présentant souvent des caractéristiques spécifiques aux polymères, ces structures y associent des propriétés de multivalence, d’adhésivité et de reconnaissance moléculaire, favorables à leur utilisation dans le
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Crohn, Kara Shea Davis. "The influence of evaluators' principles on evaluation resource decisions." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1925751641&sid=7&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Deligey, Fabien. "Caractérisation RMN de matériaux hybrides pour l’encapsulation de principes actifs." Thesis, Université de Lorraine, 2019. http://www.theses.fr/2019LORR0093/document.

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Actuellement, une voie de développement de formulations médicamenteuses novatrices passe par la vectorisation de principes actifs connus dans des nanoparticules. Des matériaux hybrides sont ainsi formés, possédant de nouvelles propriétés liées au nano-confinement. Les travaux ici menés s’appuient sur la sensibilité de la Résonance Magnétique Nucléaire (RMN) du solide aux phénomènes prenant place aux échelles moléculaires, pour effectuer une analyse structurelle et dynamique de deux vecteurs. Le premier, hydrophile, est une matrice nanoporeuse de silice sol-gel, dans laquelle sont confinés des
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Donati, Alessandra. "Le principe de précaution en droit de l'Union européenne." Thesis, Paris 1, 2019. http://www.theses.fr/2019PA01D018.

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Partant de la prémisse de la nature flexible et complexe du principe de précaution en droit européen, le but de cette étude a été d'en donner une interprétation polycentrique, fondée sur la diversité plutôt que sur l’uniformité. Pour atteindre un tel objectif, une méthode issue du pluralisme méthodologique a été employée. Celle-ci nous a permis de rechercher la uniras multiplex parmi les différentes définitions et applications de ce principe. La thèse ici soutenue a consisté à démontrer que l'interprétation polycentrique du principe de précaution peut être construite à partir de deux concepts
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ALMEIDA, MARIA FATIMA LUDOVICO DE. "CORPORATE SUSTAINABILITY, TECHNOLOGICAL INNOVATION AND ADAPTIVE PLANNING: FROM PRINCIPLES TO ACTION." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2006. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=9230@1.

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PETRÓLEO BRASILEIRO S. A.<br>O paradigma de desenvolvimento sustentável traz para as empresas dois grandes desafios: por um lado, gerar inovações necessárias à existência humana sustentável e, por outro, vencer resistências da sociedade quanto aos novos produtos e serviços. Partindo-se do pressuposto de que futuras tecnologias e inovações tecnológicas impulsionarão negócios mais sustentáveis, propiciando às empresas novas opções de criação de valor, o desafio é descobrir de que maneira as empresas que atuam em ambientes cada vez mais complexos possam incorporar a visão de sustentabilida
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Mustafa, Mudassir Imran. "Design Principles for Data Export : Action Design Research in U-CARE." Thesis, Uppsala universitet, Institutionen för informatik och media, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180061.

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In this thesis, we report the findings of designing data export functionality in Uppsala University Psychosocial Care Program (U-CARE) at Uppsala University. The aim of this thesis was to explore the design space for generic data export functionality in data centric clinical research applications for data analysis. This was attained by the construction and evaluation of a prototype for a data-centric clinical research application. For this purpose Action Design Research (ADR) was conducted, situated in the domain of clinical research. The results consist of a set of design principles expressin
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Brock, Orion D. "Using Scientific Teaching Principles to Teach Genetic Modification." Capital University Honors Theses / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=caphonors1581601024384515.

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Ramadan, Alyaa Adel. "Etude de systèmes lipidiques de délivrance de principes actifs." Phd thesis, Université d'Angers, 2010. http://tel.archives-ouvertes.fr/tel-00586347.

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Cette thèse met en évidence l'importance des transporteurs lipidiques et leurs implications pharmaceutiques dans la délivrance de principes actifs de nature différente, par voie orale et/ou par voie cutanée. L'introduction générale de cette thèse donne un aperçu des différents types é en mettant l'accent sur les nanoparticules lipidiques solides ( SLN ) et les nanocapsules lipidiques ( LNC ). Dans la première partie, les SLN chargées avec le propionate de clobétasol ( CP ), ont été développées et formulées en un hydrogel pour une long terme corticothérapie topique. Les études du transport ex v
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Ramadan, Alyaa. "Etude de systèmes lipidiques de délivrance de principes actifs." Angers, 2010. http://www.theses.fr/2010ANGE0030.

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Cette thèse met en évidence l'importance des transporteurs lipidiques et leurs implications pharmaceutiques dans la délivrance de principes actifs de nature différente, par voie orale et/ou par voie cutanée. L'introduction générale de cette thèse donne un aperçu des différents types é en mettant l'accent sur les nanoparticules lipidiques solides ( SLN ) et les nanocapsules lipidiques ( LNC ). Dans la première partie, les SLN chargées avec le propionate de clobétasol ( CP ), ont été développées et formulées en un hydrogel pour une long terme corticothérapie topique. Les études du transport ex v
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Butler, Angela Suzanne. "Principals' Content Knowledge: Examining the Relationship between Principals' Reading Knowledge and Leadership Actions from Principals' and Teachers' Perceptions." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3023.

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Principals' leadership content knowledge in reading was investigated by examining the relationship between the perceived reading knowledge of principals and perceived leadership actions principals take to support reading instruction. Survey results from 78 principals and 1,876 teachers were analyzed. Results showed a positive, statistically significant correlation between principals' perceptions of their reading knowledge and principals' perceptions of the actions they take to support reading. A stronger positive, significant correlation between teachers' perceptions of their principal's readi
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Hallink, Robert Willem. "The Application of Design Principles on Fast-Action Puzzle Games : A study on how the use of design principles affect how players perform in Fast-Action Puzzle Games." Thesis, Linnéuniversitetet, Institutionen för datavetenskap och medieteknik (DM), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-90230.

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This thesis studies a few established design principles which were implemented in a developed fast-action puzzle game prototype. The aim was to study how several design principles affected the performance of players. The prototype was described as a Time-Based Memory Mashup with six different ”presets” based on the established design principles in which small changes occur. All participants in the study played through all six presets. Gameplay data was gathered from the participating users and were automatically recorded into a database in order to determine which preset was the most successfu
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McCollough, Andrew Willis 1974. "The Influence of Gestalt Grouping Principles on Active Visual Representations: Neurophysiological Evidence." Thesis, University of Oregon, 2011. http://hdl.handle.net/1794/11555.

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xiii, 143 p. : ill. (some col.)<br>The cognitive ability to group information into chunks is a well known phenomenon, however, the effects of chunking on visual representations is not well understood. Here we investigate the effects of visual chunking using Gestalt grouping principles in two tasks: visual working memory change detection and multiple object tracking. Though both these tasks have been used to study cognitive functions in the past, including object-based attention, attentional control and working memory capacity, the effect of grouping on mental representations in these tasks has
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Leshinskaya, Anna. "Principled Neural Partitions Among Aspects of Artifact and Action Concepts." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467200.

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The research in this dissertation investigates the neural implementation of conceptual knowledge: a level of representation characterized by broad generality and independence from all sensory or motor channels. Decades of neuropsychological work have established that conceptual knowledge is not represented in a single neural locus, but rather across multiple neural loci, and that these loci are often content-selective: they are responsible for certain aspects of conceptual knowledge (e.g., animals; color) more than others. On what basis are these partitions delineated, and what determines thei
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Cowan, Susan D'Ette Fly. "Principals' actions to influence change, for school success." Full text (off-campus access restricted to users with UT Austin EID) Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3026195.

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Walton, Timothy J. "An action principle of the electrodynamics of moving elastic media." Thesis, Lancaster University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527174.

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Castagnos, Pauline. "Vésicules catanioniques : design et mécanismes de délivrance de principes actifs." Toulouse 3, 2011. http://thesesups.ups-tlse.fr/1412/.

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Les tensioactifs catanioniques dérivés de sucre s'associent spontanément sous forme de vésicules, qui peuvent aussi bien encapsuler des principes actifs hydrophiles dans leur cœur aqueux qu'insérer des drogues hydrophobes ou amphiphiles dans leur bicouche membranaire. Leur biocompatibilité ainsi que leur stabilité dans le temps et à la dilution dans des milieux biologiques en font des systèmes moléculaires organisés adaptés à la vectorisation d'actifs pharmaceutiques. L'étude mécanistique développée dans le cadre de ces travaux a montré que ces systèmes éco-conçus et de composition ajustable s
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Bonaventura, Nathalie. "Signification de la voie lymphatique dans l'absorption de principes actifs." Strasbourg 1, 1988. http://www.theses.fr/1988STR15024.

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43

Philippe, Isabelle. "Liberation controlee de principes actifs a partir de matrices hydrophiles." Strasbourg 1, 1990. http://www.theses.fr/1990STR15031.

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44

Dekyndt, Bérengère. "La libération modifiée de principes actifs, développement de deux approches." Thesis, Lille 2, 2015. http://www.theses.fr/2015LIL2S005.

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Les thérapeutiques individualisées et ciblées se développent actuellement, les formes galéniques évoluent donc en parallèle pour contrôler la libération des principes actifs (PA) et les conduire au plus proche des sites d’intérêts. Les formes orales solides représentent les formulations galéniques les plus utilisées, faciles d’emploi, indolores et réduisant le risque d’infection. Lors de leur conception, il est aussi possible de moduler la libération du PA.Deux approches sont étudiées dans ce manuscrit, l’une correspond au ciblage de la libération d’un PA vers son site d’action thérapeutique q
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45

Richard, Claire. "Formulation de vésicules catanioniques pour l'administration topique de principes actifs." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30259.

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L'administration de principes actifs de manière locale et externe permet de contrôler leur biodisponibilité et de prolonger leur action thérapeutique sur le site à traiter. Cependant, la délivrance au sein des couches profondes de la peau est un challenge pour la recherche dermatologique car ce tissu représente une barrière difficilement franchissable. Il permet ainsi de protéger l'organisme mais c'est un frein pour l'administration de médicaments par voie cutanée. De nombreux systèmes ont été imaginés afin d'améliorer le passage d'actifs à travers la peau : promoteurs chimiques de pénétration
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46

Gebretnsae, Samson Yebio. "Synthetic studies toward pavettamine, the active principle from Pavetta harborii." Diss., University of Pretoria, 2005. http://hdl.handle.net/2263/31186.

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Gousiekte (“quick” disease) is a plant-induced cardiomyopathy of livestock in South Africa, that is characterized by the sudden death of animals within a period of 3-6 weeks after the initial ingestion of toxic plant material. Six species of three genera of the Rubiaceae family viz. Pachystigma pygmaeum, P. thamnus, and P. latifolium; Pavetta harborii and P. schuman-niana, and Fadogia homblei have been identified as the causative agents of the disease. The toxin responsible for the poisoning, named pavettamine, has been isolated and the structure and absolute configuration established as (2S,4
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47

Skandarani, Nadia. "Développement de nanocapsules lipidiques pour la délivrance de principes actifs." Thesis, Besançon, 2014. http://www.theses.fr/2014BESA2071/document.

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Le développement des nanotechnologies dans le domaine médical a suscité un engouement considérable ces dernières années, notamment l’utilisation de nanoparticules pour la vectorisation de principes actifs. Les nanoparticules offrent des perspectives uniques pour la vectorisation et la délivrance de principes actifs qu’ils soient des gènes (thérapie génique),des anti-cancéreux (chimiothérapie) ou encore des agents photosensibilisateurs (photothérapie dynamique, TPD). Le défi majeur reste cependant l’acheminement des molécules thérapeutiques jusqu’à leur site d’action, tout en gardant leur intég
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48

Chaouat, Clara. "Conception de nouveaux systèmes de formulation d'actifs dépigmentants, en vue de leur utilisation par voie cutanée." Toulouse 3, 2013. http://thesesups.ups-tlse.fr/1947/.

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L'encapsulation de molécules actives est au centre de la boîte à outils du formulateur du troisième millénaire. Le recours à cette technique est de plus en plus employée car cette dernière présente de nombreux avantages ; libération contrôlée de molécules actives de leur environnement, diminution de la toxicité des actifs ou encore véhiculer le principe actif jusqu'à sa cible. La peau qui constitue une barrière physiologique a pour fonction d'assurer une protection biologique et physiologique en empêchant la pénétration d'agents pathogènes et de xénobiotiques. L'industrie ne développant pas de
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Holmberg, Staffan. "Principals' goal-setting and actions while managing : An explorative study of locally-created goals and principals’ actions while managing their schools." Thesis, Uppsala universitet, Institutionen för pedagogik, didaktik och utbildningsstudier, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-235236.

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Abstract: Large amounts of research have been performed regarding goal-setting and leadership and its effect on organizational performance. However, in school settings, the amount of performed research about leadership performance in relation to goal-setting is limited. The aim of the study was, therefore, to analyze specificity of locally-created goals and the principal’s performance-affecting behaviors during meetings, especially in relation to set goals. Based on Komaki’s research on managerial behavior structured observation was used to analyze the principal’s actions while leading meeting
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Lin, Tongling. "Path probability and an extension of least action principle to random motion." Phd thesis, Université du Maine, 2013. http://tel.archives-ouvertes.fr/tel-00795600.

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The present thesis is devoted to the study of path probability of random motion on the basis of an extension of Hamiltonian/Lagrangian mechanics to stochastic dynamics. The path probability is first investigated by numerical simulation for Gaussian stochastic motion of non dissipative systems. This ideal dynamical model implies that, apart from the Gaussian random forces, the system is only subject to conservative forces. This model can be applied to underdamped real random motion in the presence of friction force when the dissipated energy is negligible with respect to the variation of the po
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