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1

UMAR PAPUTUNGAN, JANE SIT ONIBALA, WAPSIATY UTIAH, AFRIZA YELNETTY, and CHARLES L KAUNANG. "Utilization of liquid multi-microbe probiotics supplemented urea red palm sugar block as a potential improving balance of microorganisms in digestive tract for cattle economical production." Open Access Research Journal of Science and Technology 12, no. 1 (2024): 136–47. http://dx.doi.org/10.53022/oarjst.2024.12.1.0124.

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Probiotics are live microbial feed supplements, providing beneficial effects on the host animal by improving balance of microorganisms in digestive tract. This study aims to examine the benefits of liquid multi-microbe probiotic supplementation on nutrient digestibility and economical production of beef cattle. The treatments were including ration control using fresh forage of King grass (Pennisetum purpureum) + 350 g of URPS-Block without liquid probiotic supplement (T0), fresh forage of King grass (Pennisetum purpureum) + 350 g of URPS-Block + liquid probiotic supplement of 2.0 cc/liter fres
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Priyadharshini, J., I. Viji Margaret, M. Barakath Nisha, and R. Ajaz Haja Mohideen. "Effect of Lactobacillus Probiotic Supplement on Growth and Haematological Performance of Indian Major Carp Labeo rohita." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 20 (2024): 26–33. http://dx.doi.org/10.56557/upjoz/2024/v45i204562.

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The influence of probiotics bacteria Lactobacillus acidophilus improves the survival, growth, and Hematological performance of the Indian major carp Rohu (Labeo rohita). After acclimation, a 60-day experimental study was conducted with four different types of treatments; namely, T1: Control, i.e. Basal feed without Probiotic supplements, T2: Basal feed with Aeromonas hydrophila, T3: Lactobacillus supplemented probiotic feed without Aeromonas hydrophila, and T4: Lactobacillus supplemented probiotic feed with A. hydrophila. After the experimental study, growth parameters were monitored through W
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Liu, Zhen-Shu, Pei-Lin Li, Yu-We Ku, and Po-Wen Chen. "Oral Administration of Recombinant Lactoferrin-Expressing Probiotics Ameliorates Diet-Induced Lipid Accumulation and Inflammation in Non-Alcoholic Fatty Liver Disease in Mice." Microorganisms 10, no. 11 (2022): 2215. http://dx.doi.org/10.3390/microorganisms10112215.

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We have recently developed probiotics that can express bovine, human, or porcine lactoferrin (LF), and the present study evaluated the effect of these probiotics in improving non-alcoholic fatty liver disease (NAFLD). Three kinds of probiotic supplements, including lactic acid bacteria (LAB), LAB/LF, and inactivated LAB/LF, were prepared. The LAB supplement was prepared from 10 viable LAB without recombinant LF-expression, the LAB/LF supplement was prepared from 10 viable probiotics expressing LF, and the inactivated LAB/LF supplement was prepared from 10 inactivated probiotics expressing LF.
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Dale, Hanna Fjeldheim, Stella Hellgren Rasmussen, Özgün Ömer Asiller, and Gülen Arslan Lied. "Probiotics in Irritable Bowel Syndrome: An Up-to-Date Systematic Review." Nutrients 11, no. 9 (2019): 2048. http://dx.doi.org/10.3390/nu11092048.

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Irritable bowel syndrome (IBS) is a frequent functional gastrointestinal disorder, and alterations in the gut microbiota composition contributes to symptom generation. The exact mechanisms of probiotics in the human body are not fully understood, but probiotic supplements are thought to improve IBS symptoms through manipulation of the gut microbiota. The aim of this systematic review was to assess the latest randomized controlled trials (RCTs) evaluating the effect of probiotic supplementation on symptoms in IBS patients. A literature search was conducted in Medline (PubMed) until March 2019.
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Astuti, Wulansih Dwi, Roni Ridwan, and Baharuddin Tappa. "Utilization of Probiotic and Organic-Cn on Ruminal Ecosystem In Vitro." Jurnal Ilmu Ternak dan Veteriner 12, no. 4 (2012): 262–67. https://doi.org/10.14334/jitv.v12i4.493.

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Improvement of nutrient intake was needed to increase cattle productivity. Probiotics and organic Cr, as feed additives, might have beneficially improve ruminant microbial ecosystem, and optimize digestion process by rumen microbes. The objective of this study was to examine the effects of combination between probiotic or mixed probiotcs and organic Cr on rumen fermentation activity. An in vitro study was held based on randomized block design with 5 treatments and 3 replications. The treatments were (A) Control ration, (B) Control ration + probiotic TSD 10, (C) Control ration + probiotic TSD 1
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Liao, Chorng-An, Cheng-Hsieh Huang, Hsieh-Hsun Ho, et al. "A Combined Supplement of Probiotic Strains AP-32, bv-77, and CP-9 Increased Akkermansia mucinphila and Reduced Non-Esterified Fatty Acids and Energy Metabolism in HFD-Induced Obese Rats." Nutrients 14, no. 3 (2022): 527. http://dx.doi.org/10.3390/nu14030527.

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Obesity is referred to as a condition in which excess body fat has accumulated to an extent that it causes negative impacts on health. The formation of body fat is regulated by complicated networks in relation to energy metabolism, and gut microbiota have been regarded as a key player. Studies have shown that supplements of probiotics provide benefits to health, including an improvement in metabolic syndrome and the control of body weight. In the present study, three probiotic strains, AP-32, bv-77, and CP-9, stood out from nine candidates using a lipid consumption assay, and were subsequently
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Lau, Neves, Ferreira-Magalhães, Carvalho, and Freitas. "Probiotic Ingestion, Obesity, and Metabolic-Related Disorders: Results from NHANES, 1999–2014." Nutrients 11, no. 7 (2019): 1482. http://dx.doi.org/10.3390/nu11071482.

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Gut microbiota dysbiosis has been recognized as having key importance in obesity- and metabolic-related diseases. Although there is increasing evidence of the potential benefits induced by probiotics in metabolic disturbances, there is a lack of large cross-sectional studies to assess population-based prevalence of probiotic intake and metabolic diseases. Our aim was to evaluate the association of probiotic ingestion with obesity, type 2 diabetes, hypertension, and dyslipidemia. A cross-sectional study was designed using data from the National Health and Nutrition Examination Survey (NHANES),
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8

Enioutina, Elena Y., R. James Keddington, Kurtis G. Hauck, et al. "Results of a Pilot Trial Assessing the Effects of Proper Oral Hygiene and a Probiotic Dietary Supplement on Oral Health in Volunteers with Oral Malodor." Microorganisms 12, no. 9 (2024): 1821. http://dx.doi.org/10.3390/microorganisms12091821.

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Persistent malodor affects many people worldwide and is usually associated with poor dental hygiene. This pilot trial aimed to determine whether proper dental hygiene (DH) and a probiotic dietary supplement support oral health in volunteers with persistent malodor. Volunteers (n = 35) were randomly assigned to the probiotic or placebo cohort. The probiotic cohort (n = 20) brushed and flossed their teeth twice daily and used probiotics for 30 days; the placebo cohort (n = 15) followed the same hygiene practices and used the placebo. The intervention phase was followed by a 30-day follow-up peri
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Zou, Siying, Xu Yang, Nihong Li, Hong Wang, Junhao Gui, and Junjun Li. "Association of probiotic ingestion with serum sex steroid hormones among pre- and postmenopausal women from the NHANES, 2013–2016." PLOS ONE 18, no. 11 (2023): e0294436. http://dx.doi.org/10.1371/journal.pone.0294436.

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Background Sex hormone-related diseases, encompassing a wide range of conditions from reproductive disorders to certain cancers, pose significant health challenges worldwide. Recent scientific investigations have highlighted the intricate interplay between the gut microbiome and sex hormone regulation, indicating the potential for microbiota-targeted interventions in the management of such diseases. Although individual studies have elucidated the influence of the gut microbiome on sex hormones, a comprehensive cross-sectional examination of the population-wide prevalence of probiotic intake an
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Pradipta, Monica Sonia Indri, Sri Harimurti, and Widodo Widodo. "Feed Supplementation with Encapsulated Indigenous Probiotic Lactic Acid Bacteria Increased Broiler Chicken Performance." ASEAN Journal on Science and Technology for Development 36, no. 1 (2019): 29–34. http://dx.doi.org/10.29037/ajstd.569.

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The oral application of probiotics in the poultry industry is time-consuming and laborious. Therefore, using a powdered probiotic supplement that can easily mix with feed is important. We investigated the effect of spray drying encapsulation on the viability of indigenous probiotic lactic acid bacteria during production and storage and evaluated broiler chicken performance after providing the supplement. Encapsulated probiotics exhibited >80% survival rates after spray drying. All bacterial species maintained up to 80% cell viability rates after exposure to 80–85°C temperatures for 15 or 30
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Foroozan, Parisa, Maryam Koushkie Jahromi, Javad Nemati, Hosein Sepehri, Mohammad Amin Safari, and Serge Brand. "Probiotic Supplementation and High-Intensity Interval Training Modify Anxiety-Like Behaviors and Corticosterone in High-Fat Diet-Induced Obesity Mice." Nutrients 13, no. 6 (2021): 1762. http://dx.doi.org/10.3390/nu13061762.

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Evidence supports the role of exercise training and probiotics on reducing obesity. Considering the relationship between obesity and high-fat diet with anxiety indices, the aim of this study was to assess the effect of probiotic supplementation and high-intensity interval training (HIIT) on anxiety-like behaviors, corticosterone and obesity indices in high-fat diet (HFD)-induced obesity mice. Thirty male adult C57BL/6 mice were randomly divided into five groups: (1) Control with normal diet (CON), (2) High-fat diet (HFD), (3) HFD + exercise training (HT), (4) HFD + probiotics supplement (HP) a
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Dahl, Wendy J. "Guide to Probiotics and Health." EDIS 2016, no. 9 (2016): 6. http://dx.doi.org/10.32473/edis-fs286-2016.

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Probiotics are beneficial for gastrointestinal wellness, immunity, and a variety of other health outcomes. There are hundreds of probiotic supplements available in the marketplace and choosing a supplement can be challenging. This 6-page fact sheet provides a summary of the health benefits of probiotics that are backed by a high level of scientific evidence. Written by Wendy J. Dahl and published by the Food Science and Human Nutrition department, November 2016. FSHN16-8/FS286: A Guide to Probiotics and Health (ufl.edu)
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Zhu, Julie, Tyler Pitre, Carmen Ching, Dena Zeraatkar, and Steven Gruchy. "Safety and efficacy of probiotic supplements as adjunctive therapies in patients with COVID-19: A systematic review and meta-analysis." PLOS ONE 18, no. 3 (2023): e0278356. http://dx.doi.org/10.1371/journal.pone.0278356.

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Background and aims Oral probiotic supplementation may be a beneficial adjunctive therapy for patients with symptomatic COVID-19. However, its safety and efficacy are unclear. We aimed to investigate how probiotic supplementation impacts COVID-19 symptom trajectory and patient outcomes by conducting a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods RCTs randomizing patients with COVID-19 to probiotics were searched in PubMed Central, Embase, CINAHL, and Cochrane Library from inception to July 31, 2022. We performed a random-effects pairwise meta-analysis for
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Yu, Jiawei, Gaoyang Cao, Shuohui Yuan, Cong Luo, Jiafeng Yu, and Ming Cai. "Probiotic supplements and bone health in postmenopausal women: a meta-analysis of randomised controlled trials." BMJ Open 11, no. 3 (2021): e041393. http://dx.doi.org/10.1136/bmjopen-2020-041393.

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ObjectiveOsteoporosis is a common disease in postmenopausal women. Several studies have analysed the associations between dietary supplementation with probiotics and bone health in postmenopausal women, but the results are still controversial. We conducted this meta-analysis to assess the effects of probiotics supplement on bone mineral density (BMD) and bone turnover markers for postmenopausal women.DesignSystematic review and meta-analysis.MethodsWe systematically searched PubMed, EMBASE and the Cochrane Library from their inception to November 2020 for randomised controlled trials (RCTs) as
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15

Setyawan, Andhika Agus, Sukanto Sukanto, and Endang Widyastuti. "POPULASI BAKTERI ASAM LAKTAT PADA BUDIDAYA IKAN NILA YANG DIBERI PAKAN FERMENTASI LIMBAH PERTANIAN DENGAN SUPLEMEN ENCENG GONDOK DAN PROBIOTIK." Scripta Biologica 1, no. 1 (2014): 87. http://dx.doi.org/10.20884/1.sb.2014.1.1.32.

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The aim of this study were to determine the effect of fermented agricultural wastes feeding with supplement of water hyacinth and MEP+ probiotic towards the increasing population of intestinal Lactid Acid Bacteria (LAB) in Tilapia and to know the highest population of lactic acid bacteria after fermented agricultural waste feeding with water hyacinth supplements and MEP+ probiotic. Independent variable in this study was fermented feed with the addition of different water hyacinth and MEP+ probiotics. The experimental study was continued using completely randomized design (CRD). The dependent v
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Dr., Saba Tazeem Dr. Asghar Ali Dr. Shehla. "A COMPREHENSIVE STUDY EFFECT OF PROBIOTIC YOGURT CONSUMPTION ON OXIDATIVE STRESS FACTORS IN CHILDREN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 14485–88. https://doi.org/10.5281/zenodo.1999867.

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<strong><em>Introduction: </em></strong><em>Probiotics are living microbial food supplements which beneficially affect the host body by improving its microbial balance. It has been indicated that the intake of probiotic product supplements have potential health benefits for healthy persons and also in disease prevention. O<strong>bjectives of the study: </strong>The basic aim of the study was to analyze the effect of probiotic yogurt consumption on oxidative stress factors in children. <strong>Methodology of the study: </strong>This study was conducted at Ganga Ram hospital during 2018. For th
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Aulia, Deni, Kurnia Sada Harahap, and Artin Indrayati. "EFFECT OF DIETARY PROBIOTIC SUPPLEMENTATION ON GROWTH PERFORMANCE, SURVIVAL RATE, AND CONDITION FACTOR OF RED NILE TILAPIA (Oreochromis niloticus L.)." Jurnal Perikanan Unram 15, no. 2 (2025): 859–67. https://doi.org/10.29303/jp.v15i2.1464.

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Red Nile Tilapia (Oreochromis niloticus L.) is one of the important commodities in aquaculture, possessing high economic value and promising prospects for supporting the economy and food security. Various efforts have been made to increase fish production, one of which is through the use of feed additives. Probiotics have been widely used in aquaculture, either as a feed supplement or applied directly to the culture media. This study aims to compare the growth, survival rate, and condition factor of Red Nila Tilapia fed with probiotic-supplemented feed and those without probiotics. The study w
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Dardmeh, Fereshteh, Hans Ingolf Nielsen, Hiva Alipour, Benedict Kjærgaard, Erik Brandsborg, and Parisa Gazerani. "Potential Nociceptive Regulatory Effect of ProbioticLactobacillus rhamnosusPB01 (DSM 14870) on Mechanical Sensitivity in Diet-Induced Obesity Model." Pain Research and Management 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/5080438.

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Treatments for obesity have been shown to reduce pain secondary to weight loss. Intestinal microbiota, as an endogenous factor, influences obesity and pain sensitivity but the effect of oral probiotic supplementation on musculoskeletal pain perception has not been studied systematically. The present study examined the effect of a single daily oral dose (1 × 109CFU) of probiotics (Lactobacillus rhamnosusPB01, DSM14870) supplement on mechanical pain thresholds in behaving diet-induced obese (DIO) mice and their normal weight (NW) controls. The mice (N=24, 6-week-old male) were randomly divided i
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Supriya, Yadav* Dr. S. V. Raut. "Development of a Probiotic-Based Health Supplement: Screening, Characterization, and Stability Assessment." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 2658–77. https://doi.org/10.5281/zenodo.15096989.

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Probiotic-based health supplements have gained considerable attention due to their potential benefits in improving gut health, immunity, and overall well-being. This study focuses on the screening, characterization, and formulation of a probiotic health supplement, emphasizing stability assessment to ensure long-term efficacy. Lactic acid bacteria (LAB) were isolated from dairy samples collected from various sources and characterized using biochemical and molecular techniques. Their ability to survive under different pH conditions, bile salt concentrations, NaCl levels, and cholesterol assimil
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Lualhati, Christian, Karl Reginald Managa, Charity Castillo, Phoebe Lyndia Llantada, and Arnel Del Barrio. "Effects of Probiotic Supplementation on Growth Performance, Nutrient Digestibility, and Enteric Methane Emission of Growing Dairy Buffaloes (Bubalus bubalis L.)." Philippine Agricultural Scientist 108, no. 2 (2025): 119–30. https://doi.org/10.62550/dab0502224.

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This study assessed the impact of probiotics on the growth performance, nutrient digestibility, and enteric methane emission of 4 growing dairy buffaloes (Bubalus bubalis L.) with similar body weight, age, and sex. The animals were allocated into 4 treatments following a Latin Square design: control/no probiotic supplement (Trt 1); with 5 mL probiotic supplement (Trt 2); with 10 mL probiotic supplement (Trt 3); and with 15 mL probiotic supplement (Trt 4). The growers were offered the dietary treatments at the start of the adaptation phase up to the end of the experimental phase per period. Ani
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Anwar, Haseeb, Ghulam Hussain, Azhar Rasul, et al. "Potential role of probiotic species in ameliorating oxidative stress, effect on liver profile and hormones in male albino rat model." European Journal of Inflammation 19 (January 2021): 205873922110161. http://dx.doi.org/10.1177/20587392211016119.

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Probiotics are living micro-organism preparations which can vigorously inhibit the probable pathogens colonization in the gut microbial ecology. Current experiment was designed to investigate the efficacy of imported probiotic species compared with the indigenous probiotics species on the oxidative stress, enzymes, and hormones in animal model. Thirty Albino rats were equally divided into three groups with 10 rats ( n = 10) in each group as Control (C), supplemented with imported probiotic species (IP), and supplemented with indigenous probiotics species (InP) for 21 days under controlled envi
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Subhajit, Patra Priyanka Ray Prapti Chakraborty*. "Review on Probiotics as A Health Supplement." International Journal of Scientific Research and Technology 2, no. 6 (2025): 24–32. https://doi.org/10.5281/zenodo.15567983.

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The organisational characteristics of microbial cells and their function in a probiotic will be the primary topics of this review. Spatial organisation is a quality that sets all biological systems apart. Even the smallest biological organisms, bacteria, have precise internal structures and well-defined geometries. This review will additionally shed light regarding how these probiotics support our bodies' ability to maintain a healthy balance and avoid numerous diseases. They achieve this by decreasing inflammation and strengthening our immune systems.The most common microbial species for this
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TOADER, Ionel, Aurel ȘARA, Mihai BENTEA, and Mirela CADAR. "Influence of YEA-SACC 1026 Probiotic on Meat Quality in Chicken Broilers." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies 74, no. 1 (2017): 64. http://dx.doi.org/10.15835/buasvmcn-asb:12291.

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The use of probiotics, as fodder supplement for chickens, could stimulate meat quality that is a very important criterion especially for human consumption markets. The study had in view the effects of powdery YEA-SACC 1026 probiotic on meat quality in chicken broilers. There were studied 75 meat chickens of Ross-308 hybrid grouped on three lots of 25 capita/lot during an experimental period of 42 days. In the mixed fodder of experimental lots was added powdery YEA-SACC 1026 probiotic in proportion of 0.1% in lot L1(E) and in proportion of 0.25% in lot L2(E). In the experiment end, were effecte
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Ciernikova, Sona, Michal Mego, Maria Semanova, et al. "Probiotic Survey in Cancer Patients Treated in the Outpatient Department in a Comprehensive Cancer Center." Integrative Cancer Therapies 16, no. 2 (2016): 188–95. http://dx.doi.org/10.1177/1534735416643828.

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Purpose. Availability without prescription restriction, low cost, and simple oral administration allow cancer patients to use probiotics without knowledge of potential risks. We present a survey of probiotic use and the association with patient tumor characteristics in cancer patients treated at the outpatient department of the National Cancer Institute in Slovakia. Patients and Methods. Between March and December 2014, 499 patients were asked to evaluate their overall experience with probiotics by questionnaire form, including the length and method of use relative to anticancer therapy, expec
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Sahandi, Javad, Hojatollah Jafaryan, Mehdi Soltani, and Pouneh Ebrahimi. "Enhancement of growth performance and hematological changes in rainbow trout (Onchorhynchus mykiss) alevins fed with Bifidobacterium bacteria." Journal of Fisheries 5, no. 1 (2017): 439–44. http://dx.doi.org/10.17017/j.fish.51.

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The study of probiotic application as an important rearing strategy was started more than 30 years ago and most of these studies were carried out to increase growth and survival of larvae. Effect of Bifidobacterium animalis PTTC-1631 and B. lactis PTTC-1736 as probiotic supplement has been studied on growth performance and hematological changes on rainbow trout, Oncorhynchus mykiss alevins with initial body weight of 0.583 ± 0.197 g. The commercial diet was supplemented with graded levels of probiotics (1×107, 2×107 and 3×107 CFU g-1 dry feed) to obtain 3 sets of experimental diets (T1, T2, an
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Karpenko, L. Yu, N. A. Sidorova, A. A. Bakhta, et al. "Assessment of hematological parameters of rainbow trout when probiotic preparations are introduced into the diet." International Journal of Veterinary Medicine, no. 1 (June 3, 2025): 271–77. https://doi.org/10.52419/issn2072-2419.2025.1.271.

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Increasing aquaculture production is an important condition for ensuring food security in Russia and promoting socio-economic development of the regions. Parasalmo mykiss or rainbow trout is one of the most popular objects of industrial fish farming due to its commercial value and biological characteristics, including rapid growth and resistance to intensive cultivation conditions. The purpose of this study was to examine the morphological parameters of rainbow trout (Parasalmo mykiss) blood when introducing various probiotic preparations into the diet. To assess the physiological state of the
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AZEVEDO, JORGE F. DE, CATCHIA HERMES-ULIANA, DIRLENE P. LIMA, DÉBORA M. G. SANT'ANA, GILBERTO ALVES, and EDUARDO J. A. ARAÚJO. "Probiotics protect the intestinal wall of morphological changes caused by malnutrition." Anais da Academia Brasileira de Ciências 86, no. 3 (2014): 1303–14. http://dx.doi.org/10.1590/0001-3765201420130224.

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This study sought to morphometrically analyze the jejunal wall of protein-malnourished rats administered a probiotic supplement. The sample consisted of recently weaned Wistar rats (Rattus norvegicus) distributed among four groups: animals given a commercial diet (G1, n = 4); animals given the same ration as G1 plus a probiotic supplement (G2, n = 4); animals given a 4% protein diet (G3, n = 4); and animals given the same ration as G3 plus a probiotic supplement (G4, n = 4). After 12 weeks, part of the jejunum was harvested and subjected to routine histological processing. Transverse sections
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Li, Qing Qing, Juan Xu, Mei Ling Chen, Hui Ruan, Guo Qing He, and Xue Qian Wu. "Application of a Novel Freeze-Dried Aerotolerant Bifidobacterium animailis Subsp. Lactis Qq08 (Bl Qq08) in Probiotic Yoghurt Production." Applied Mechanics and Materials 140 (November 2011): 268–72. http://dx.doi.org/10.4028/www.scientific.net/amm.140.268.

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Probiotics are of great beneficial functions, especially on gastrointestinal health. Probiotic yoghurt is gaining popularity for it is the main way to supplement probiotics. In this study, a novel probiotic yoghurt was made by adding a freeze-dried aerotolerant Bifidobacterium animailis subsp. lactis Qq08 (Bl Qq08) to traditional yoghurt. Microbial, physical, chemical and flavor changes of the yoghurt during cold storage were analyzed weekly to study the effects of Bifidobacterium addition on the yoghurt quality. Results showed that the addition of Bl Qq08 didn’t significantly affect the cell
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Barbosa, Aline Maria Silva, Maria Paula Souza Carvalho, Luciana de Paula Naves, et al. "Performance and Health Parameters of Sows and Their Litters Using a Probiotic Supplement Composed of Bacillus subtilis 541 and Bacillus amyloliquefaciens 516." Animals 14, no. 23 (2024): 3511. https://doi.org/10.3390/ani14233511.

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This study investigated the efficacy of using probiotics on the performance and health parameters of sows and their litters. A randomized block design was used with 584 sows and 292 replications, with two dietary treatments: the control group (basal diet without probiotics) and the probiotic group (basal diet supplemented with 400 g/ton of a probiotic composed of Bacillus subtilis (B. subtilis) 541 and Bacillus amyloliquefaciens (B. amyloliquefaciens) 516). Feed intake was evaluated throughout the experimental period. Bodyweight and backfat thickness of the sows were measured at the beginning
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Rybachuk, Zh V., O. I. Shkromada, A. V. Predko, and Y. A. Dudchenko. "Influence of probiotics “Immunobacterin-D” on biocenoses and development of the gastrointestinal tract of calves." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 22, no. 98 (2020): 22–27. http://dx.doi.org/10.32718/nvlvet9804.

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The paper presents the results of an experiment on the use of enzyme-probiotic supplement “Immunobacterin-D” for calves in the first two months of life. Probiotics are used in animal husbandry for the prevention and treatment of infectious diseases, increase immunity, correction of the microflora after antibiotic therapy, prevention of stress, increase growth. The study was conducted in a private farm in the Lyubar district of Zhytomyr region, which kept cattle of different ages. In a randomized controlled trial, two experimental groups of six animals were formed in each on the principle of an
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Zikou, Eva, Nikolas Dovrolis, Charilaos Dimosthenopoulos, Maria Gazouli, and Konstantinos Makrilakis. "The Effect of Probiotic Supplements on Metabolic Parameters of People with Type 2 Diabetes in Greece—A Randomized, Double-Blind, Placebo-Controlled Study." Nutrients 15, no. 21 (2023): 4663. http://dx.doi.org/10.3390/nu15214663.

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The role of probiotic supplementation in type 2 diabetes (T2D) treatment is controversial. The present study aimed to assess the effects of a multi-strain probiotic supplement (LactoLevureR (containing Lactobacillus acidophilus, Lactobacillus plantarum, Bifidobacterium lactis, and Saccharomyces boulardii)) over 6 months, primarily on glycemic control as well as on lipid levels and alterations in the gut microbiome, among individuals with T2D residing in Greece. A total of 91 adults with T2D (mean age [±SD] 65.12 ± 10.92 years, 62.6% males) were randomized to receive the probiotic supplement or
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Dadlani, Apaar, Khushboo Gala, Jayesh Rai, Shesh Rai, and Gerald Dryden. "BRAIN FOG IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE, AND ASSOCIATION WITH USE OF PROBIOTICS." Inflammatory Bowel Diseases 28, Supplement_1 (2022): S66—S67. http://dx.doi.org/10.1093/ibd/izac015.108.

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Abstract INTRODUCTION Brain fog has been extensively studied in patients with inflammatory bowel disease (IBD). Probiotics have been shown to increase the incidence of brain fog in patients independently. There is a high prevalence of probiotic consumption in patients with IBD in clinical practice, whether by a physician or not. We aimed to study if there was an association between brain fog and IBD patients who took probiotics and those who did not. METHODS We conducted a cross-sectional study of patients visiting IBD clinic. Patients over the age of 18 with a biopsy-proven diagnosis of infla
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Sulistyanti Dian Rachmawati and Wiji Lestari. "EFFECTIVENESS OF PROBIOTIC SUPPLEMENT ON HELICOBACTER PYLORI INFECTION ERADICATION IN GASTRIC ULCERS." IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) 6, no. 1 (2023): 22–29. http://dx.doi.org/10.54773/ijcnp.v6i1.114.

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Background: Helicobacter pylori colonizes the gastric mucosa in 50% of the human population. H. pylori infection causes several upper gastrointestinal tract diseases such as chronic gastritis, peptic ulcer, duodenal ulcer, and gastric cancer. H. pylori is also associated with a high risk of developing gastric adenocarcinoma. The World Health Organization classifies H. pylori infection as a class 1 carcinogen. Giving probiotics may improve the immune system and suppress the effects of pathogens. However, mixed results were obtained from the use of various kinds of bacteria and fungi as probioti
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Colla, Elielma Cristiane Xavier, Daiane Meneguzzi, Thaís Fernandes Mendonça Mota, et al. "A Functional Food Supplement Enriched with Vegetable Proteins and Probiotics: A Hyperproteic and Probiotic-Formulated Product." Fermentation 11, no. 2 (2025): 63. https://doi.org/10.3390/fermentation11020063.

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Functional foods enriched with probiotics can help maintain health and enhance mental and cognitive function. This research focused on developing and characterizing a high-protein dietary supplement containing a blend of plant proteins and probiotic cells (Lactobacillus reuteri LRE 02 ID 1774). An additional systematic review aimed to showcase the current state of the art of the research topic and complement the study’s findings. The supplement demonstrated high nutritional quality, particularly in protein content and amino acid profile, providing all essential amino acids and branched-chain a
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Wang, Anyi, and Qixin Zhong. "Drying of probiotics to enhance the viability during preparation, storage, food application, and digestion: A review." Comprehensive Reviews in Food Science and Food Safety 23, no. 1 (2023): 1–30. http://dx.doi.org/10.1111/1541-4337.13287.

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AbstractFunctional food products containing viable probiotics have become increasingly popular and demand for probiotic ingredients that maintain viability and stability during processing, storage, and gastrointestinal digestions. This has resulted in heightened research and development of powdered probiotic ingredients. The aim of this review is to overview the development of dried probiotics from upstream identification to downstream applications in food. Free probiotic bacteria are susceptible to various environmental stresses during food processing, storage, and after ingestion, necessitat
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Krisnan, Rantan, Budi Haryanto, and Komang G. Wiryawan. "The effect of combined probiotics with catalyst supplementation on digestion and rumen characteristic in Priangan sheep." Jurnal Ilmu Ternak dan Veteriner 14, no. 4 (2013): 262–69. https://doi.org/10.14334/jitv.v14i4.305.

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An experiment was carried out to investigate the effect of combined supplementation of probiotics and catalyst on digestion and rumen characteristic in Priangan sheep. The trial was conducted using 16 heads of young male Priangan sheep with average initial weight of 18 kg in completely randomized design with factorial 2x2 and 4 replication. The first factor was two types of probiotics mixed with catalyst supplement, while the second factor was two levels of supplement percentage of catalyst at 0.5 and 1.0% of concentrate. The type of probiotics applied was probion and probiotics of buffaloes r
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Foysal, Md Javed, Thi Thu Thuy Nguyen, Md Reaz Chaklader, et al. "Marked variations in gut microbiota and some innate immune responses of fresh water crayfish, marron (Cherax cainii, Austin 2002) fed dietary supplementation of Clostridium butyricum." PeerJ 7 (August 27, 2019): e7553. http://dx.doi.org/10.7717/peerj.7553.

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This study aimed to investigate the effects of Clostridium butyricum as a dietary probiotic supplement in fishmeal based diet on growth, gut microbiota and immune performance of marron (Cherax cainii). Marron were randomly distributed into two different treatment groups, control and probiotic fed group. After 42 days of feeding trial, the results revealed a significant (P &lt; 0.05) increase in growth due to increase in number of moults in marron fed probiotics. The probiotic diet also significantly enhanced the total haemocyte counts (THC), lysozyme activity in the haemolymph and protein cont
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Nelfa C. Gil. "Fried Chicken Quality As Affected By Probiotic Feeding Supplementation." Journal of Science, Engineering and Technology (JSET) 3, no. 1 (2015): 97–105. http://dx.doi.org/10.61569/xv6q4e32.

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Probiotics had been found promising in controlling food spoilage and pathogenic microorganisms thus maintaining the integrity of meat during processing. The study meant to determine the effect of locally-prepared probiotics from different growth media as feed supplement on the fried chicken’s sensory characteristics in terms of color, flavor, juiciness, tenderness, and general acceptability. Results showed that sensory acceptability of fried chicken flavor was significantly influenced by the probiotic from milk substrate (T1) with the highest mean acceptability rating of 8.17 and is characteri
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Koesnoe, Sukamto, Nuning Masjkuri, Asri Adisasmita, et al. "A randomized controlled trial to evaluate the effect of influenza vaccination and probiotic supplementation on immune response and incidence of influenza-like illness in an elderly population in Indonesia." PLOS ONE 16, no. 12 (2021): e0250234. http://dx.doi.org/10.1371/journal.pone.0250234.

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Aim To investigate the effect of influenza vaccination with or without probiotic supplementation on the immune response and incidence of influenza-like illness (ILI) in the elderly. Methods A randomized double-blind, placebo-controlled trial with a modified factorial design was conducted in 554 healthy elderly subjects aged 67 ± 5.6 (ranging from 60–90) years old in the Primary Health Care Center (Puskesmas area) of the Pulo Gadung District East Jakarta. Subjects received either a trivalent influenza vaccine or placebo at the start of the study, and a probiotic supplement (Lactobacillus helvet
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McFarland, Lynne V., Gail Hecht, Mary E. Sanders, et al. "Recommendations to Improve Quality of Probiotic Systematic Reviews With Meta-Analyses." JAMA Network Open 6, no. 12 (2023): e2346872. http://dx.doi.org/10.1001/jamanetworkopen.2023.46872.

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ImportanceSystematic reviews and meta-analyses often report conflicting results when assessing evidence for probiotic efficacy, partially because of the lack of understanding of the unique features of probiotic trials. As a consequence, clinical decisions on the use of probiotics have been confusing.ObjectiveTo provide recommendations to improve the quality and consistency of systematic reviews with meta-analyses on probiotics, so evidence-based clinical decisions can be made with more clarity.Evidence ReviewFor this consensus statement, an updated literature review was conducted (January 1, 2
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Lima, Erica G., Rejane S. Parpinelli, Pedro R. Santos, Alexandre S. B. Azevedo, Maria J. Sereia, and Vagner A. Arnaut de Toledo. "Optimization of Protein Feed Fermentation Process for Supplementation of Apis Mellifera Honeybees." Journal of Apicultural Science 64, no. 1 (2020): 15–27. http://dx.doi.org/10.2478/jas-2020-0001.

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AbstractAn alternative to natural food shortage for honeybees is the provision of supplements. The objective of this research was to develop a method with ideal conditions for the fermentation of a protein supplement for honeybees. The microorganisms used were Lactobacilli, Bifidobacteria and Saccharomyces and the inulin prebiotic. There was an increase in lactic acid and a decrease in pH over a five-day fermentation period. The amount of acid bacteria present was 108–109 CFU/g of supplement. In the first phase the temperature and the humidity had significantly affected the fermentation but th
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Kananykhina, О., and Т. Turpurova. "CHARACTERISTICS AND APPLICATION OF BIOPOLYMERS FOR MICROENCAPSULATION OF BIOLOGICALLY ACTIVE SUBSTANCES." Grain Products and Mixed Fodder’s 23, no. 2 (2024): 32–38. http://dx.doi.org/10.15673/gpmf.v23i2.2742.

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In the feeding of highly productive agricultural animals and poultry, an important role belongs to the quality and safety of compound feed products, for the production of which premixes or preparations of biologically active substances are used. Increasingly, probiotic supplements based on live microorganisms are used in the feeding of farm animals and poultry, which, among other things, provide stable immunity to infectious diseases without using antibiotics in the diet. As a result, the general condition improves and the productivity of animals and the quality of livestock products increase.
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Raposo, Pamela J. F., Antoinette T. Nguyen, Emma K. A. Schmidt, et al. "No Beneficial Effects of the Alfasigma VSL#3 Probiotic Treatment After Cervical Spinal Cord Injury in Rats." Topics in Spinal Cord Injury Rehabilitation 31, no. 1 (2025): 1–16. https://doi.org/10.46292/sci24-00004.

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Background: The bidirectional communication between the gastrointestinal tract and the central nervous system appears to be linked to the intestinal microbiome. Research has shown that spinal cord injury (SCI) can disrupt the gut microbiome, leading to gut dysbiosis. These changes can have several negative impacts, such as exacerbated systemic inflammation and susceptibility to infection. Probiotics administered to mice with SCI have been shown to ameliorate gut dysbiosis, confer neuroprotection, and improve locomotor recovery. However, probiotics have also produced conflicting results, making
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Poberezhets, J., I. Kupchuk, V. Yaropud, and S. Burlaka. "DIGESTIBILITY OF NUTRIENTS AND BROILER CHICKEN PRODUCTIVITY UNDER THE ACTION OF PROBIOTIC ENTERO-ACTIVE." HERALD OF KHMELNYTSKYI NATIONAL UNIVERSITY 299, no. 4 (2021): 182–86. http://dx.doi.org/10.31891/2307-5732-2021-299-4-182-186.

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The probiotic “Entero-active”, due to the formation of lactic and acetic acids, creates an unfavourable pH environment for pathogenic microflora, stimulates the growth of intestinal normal flora, which has a positive effect on the composition of the microbiocenosis. In addition, probiotic microorganisms produce biologically active substances, enzymes and amino acids. The aim of the research was to investigate the digestion of feed nutrients by broiler chickens fed by the probiotic supplement Entero-active. Optimal doses of probiotic feeding are determined on the basis of obtained results. The
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Barowicz, T., W. Migdał, M. Pieszka, and Branislav Zivkovic. "The effect of linseed pufa n-3 and probiotics on fatty acid composition and cholesterol level in Longissimus dorsi muscle of fatteners." Biotehnologija u stocarstvu 19, no. 3-4 (2003): 31–36. http://dx.doi.org/10.2298/bah0304031b.

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The experiment involved 24 Polish Landrace gilts, divided into 2 groups, and fed from 70 to 100 kg b.w. with a complete mixture containing 15% full fat flax with or without 0.35% probiotic (Acid Pack 4 Way). The experiment concluded with slaughtering, and dissection, meat of Longissimus dorsi muscle was sampled to determine fatty acids composition and total cholesterol content. The supplement was observed to have no effect on fattening, slaughter and physicochemical traits of meat. The probiotic supplement did not significantly affect the composition of fatty acids in Longissimus dorsi muscle.
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Raghda Abdulhussain, Kareem, Razavi Seyed Hadi, and Mousavi Zeinab. "Survival of Free and Encapsulated Probiotics in Healthy Gummy Candy as a Carrier for Probiotic Capsules." Archives of Food and Nutritional Science 8, no. 1 (2024): 029–37. http://dx.doi.org/10.29328/journal.afns.1001059.

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Probiotic gummy candy is an innovative food that can be used as a carrier to deliver probiotics. This study aimed to manufacture healthy gummy candy (HGC) as a carrier for probiotic capsules. The ingredients' effect on the viability of probiotic capsules and free cells was evaluated for 48 days under refrigerated conditions. Also, the textural properties, overall acceptability of products, and physicochemical properties were tested. The encapsulation probiotics in sodium alginate and chitosan provided a high efficiency of 88.16%. At the same time, the encapsulated cells-based HGC (HGC-C) had h
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Case, Riley, Amanda Holder, and Ryan Bilyeu. "PSV-10 Evaluation of the effect of probiotic feed additives in the diet to improve dairy production and quality measures." Journal of Animal Science 102, Supplement_2 (2024): 335–36. http://dx.doi.org/10.1093/jas/skae102.383.

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Abstract There is limited information regarding the effectiveness of probiotic feed additives in the diet of lactating dairy cows. This study aimed to determine the effect that Fastrack probiotic had on the yield and milk quality measures of lactating dairy cows. To accomplish this goal, lactating Holstein cows (n = 80) were equally divided into two treatment groups: one supplemented with a probiotic (PRO) and one that did not receive the probiotic supplement (CON). The cows remained in their treatment groups for the duration of the 120-d study and were given ad libitum access to a total mixed
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Sebayang, F., M. Z. E. Sinaga, A. Kahiri, J. B. Tarigan, and E. K. Sitepu. "SYNBIOTIC FUNCTIONAL DRINK FROM COW MILK FERMENTED WITH KEFIR AND SUPPLEMENTED WITH INULIN." Rasayan Journal of Chemistry 15, no. 01 (2022): 395–401. http://dx.doi.org/10.31788/rjc.2022.1516683.

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Increasing awareness on health has increased demand for healthy food confirmed by raising market sales of functional food. This study aims to develop a new synergetic drink from cow milk fermented by kefir grains and supplemented by inulin. Firstly, the inulin was isolated from dahlia flower tuber while fresh cow milk was incubated with kefir grains to produce kefir probiotic drink. Next, inulin with different concentrations was added to the probiotic drink and was fermented for 48 hours at room temperature generating a symbiotic functional drink. Analysis of antimicrobial properties revealed
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Viljoen, M., A. Panzer, A. Koorts, P. Henn, and J. B. Van den Bogaerde. "The Effects of Probiotics on Symptoms and Immunoglobulin Levels of Patients with Irritable Bowel Syn-drome." Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie 23, no. 1/2 (2004): 22–24. http://dx.doi.org/10.4102/satnt.v23i1/2.189.

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The medicinal use of natural plant materials and food supplements is gaining in popularity. The Food Directorate of the Department of Health considers probiotics as a food supplement. In this double blind controlled pilot study the effects of probiotic treatment (Lactoba-cillus acidophilus and Bifidobacterium longum and bifidum) were evaluated on the symptoms and immunoglobulin levels of patients with Irritable Bowel Syndrome (IBS). Twenty-four patients who fulfilled the Drossman criteria for the diagnosis of IBS were randomised to receive either probiotics or a placebo for 28 days. Immunoglob
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Lojanica, M., M. Manojlovic, D. Jeremic, and S. Petronijevic. "The effects of probiotic Enterococcus faecium DSM 7134 in the weaned pigs nutrition." Biotehnologija u stocarstvu 26, no. 1-2 (2010): 57–64. http://dx.doi.org/10.2298/bah1002057l.

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Placing a ban on the use of antibiotics as additives for animal feed, had raised the producing risk, because of possibility for occurrence of many diseases in rearing piglets. One of alternative solutions is the use of probiotics as supplements, directly or in piglets feed. Aim of this study was to investigate the effects probiotic Enterococcus faecium DSM 7134 on the rearing piglets in the period from weaning to fattening start. This experiment included 500 piglets, divided in 2 groups, 250 piglets in experiment group (5 cycles with 50 piglets each) and 250 piglets (5 cycles with 50 piglets)
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