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Relevant bibliographies by topics / Prochlorperazine maleate

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Academic literature on the topic 'Prochlorperazine maleate'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Prochlorperazine maleate"

1

Blazheyevskiy, M. Ye, and V. P. Moroz. "The Oxidative Derivatization Method For The Indirect Spectrophotometric Determination Of Prochlorperazine In Tablets." Methods and Objects of Chemical Analysis 15, no. 3 (2020): 132–36. http://dx.doi.org/10.17721/moca.2020.132-136.

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The oxidative derivatization method by means of peroxoacid for the indirect spectrophotometric determination of Prochlorperazine Maleate is presented. Potassium hydrogen peroxymonosulfate as a derivatizing agent, yielding the Prochlorperazine sulfoxide with λmaх=338 nm is proposed. This reaction product was successfully employed for the spectrophotometric determination of the Prochlorperazine Maleate. The UV spectrophotometric determination of Prochlorperazinе as its sulfoxide proved to be the more robust and selective method. Concentration dependence of the oxidation product remains linear in

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2

Blazheyevskiy, M. Ye, Yu V. Skrypynets, A. V. Yegorova, and V. P. Antonovich. "A New Oxidative Derivatization Method For The Indirect Spectrofluorimetric Determination Of Prochlorperazine Maleate In Pharmaceutical Preparations." Methods and Objects of Chemical Analysis 14, no. 3 (2019): 140–45. http://dx.doi.org/10.17721/moca.2019.140-145.

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A new oxidative derivatization method for the indirect spectrofluorimetric determination of Prochlorperazine maleate has been presented. Potassium hydrogenperoxomonosulphate is proposed as a derivatizing agent for Prochlorperazine, yielding the strongly fluorescent sulfoxide. This reaction product was successfully employed for the spectrofluorimetric determination of the Prochlorperazine maleate. A highly sensitive, simple and rapid method has been developed for determining prochlorperazine maleate in tablets by fluorescence of its oxidation product with Oxone solution in 0.01 M sulfuric acid

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Bhagwat, G. B., S. P. Wate, and A. S. Mundhey. "DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF PROCHLORPERAZINE MALEATE AND PYRIDOXINE HYDROCHLORIDE IN TABLET DOSAGE FORM BY UV USING MULTI-COMPONENT MODE OF ANALYSIS." INDIAN DRUGS 50, no. 03 (2013): 20–25. http://dx.doi.org/10.53879/id.50.03.p0020.

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Prochlorperazine maleate and pyridoxine hydrochloride in combination are available as tablet dosage forms in the ratio of 1:5. A simple, reproducible and efficient method for the simultaneous determination of prochlorperazine maleate and pyridoxine hydrochloride in tablet dosage form has been developed. The developed method is based on the simultaneous estimation by UV Spectroscopy, using multi-component mode of analysis. In this method 0.3M HCl was used as solvent. Wavelengths selected for estimation of prochlorperazine maleate and pyridoxine hydrochloride in multi-component mode of analysis

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4

Pawar, Rajat, Ravi Sharma, and Gajanan Darwhekar. "Formulation and Evaluation of Mouth Dissolving Film of Prochlorperazine Maleate." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 110–15. http://dx.doi.org/10.22270/jddt.v9i6.3679.

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This research work was aimed to enhance the oral bioavailability and provide faster onset of action of Prochlorperazine maleate (used for the treatment nausea and vomiting) by formulating its mouth dissolving film (MDF). Prochlorperazine belongs to BCS II and oral bioavailability of it’s about 11-15%. The MDF of Prochlorperazine maleate was prepared by solvent casting method using HPMC (film forming agent),Glycerol (plasticizer), Betacyclodextrin (solubilizing agent), Citric acid (saliva stimulating agent), Mannitol (sweetening agent). The formulation was optimized by two factors, three levels

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5

Sharma, Shailesh. "Development of Fast Dissolving Buccal Patches of Prochlorperazine Maleate for Effective Management of Emesis." YMER Digital 21, no. 08 (2022): 123–36. http://dx.doi.org/10.37896/ymer21.08/13.

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The goal of this research was to increase the oral bioavailability and avoid the first pass metabolism of Prochlorperazine Maleate (used to treat nausea and vomiting) by creating its buccal patches. Prochlorperazine is a member of BCS II and has an oral bioavailability of 11– 15%. Prochlorperazine maleate buccal patches were made by solvent casting with the aid of HPMC E-15 and Chitosan (film-forming agents), Glycerol (plasticizer), Tween 80 (penetration enhancer), Citric Acid (saliva stimulating agent), Mannitol (sweetening agent), and Ethyl Cellulose (Backing membrane). Twelve total formulat

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6

Meena, Aarti, Sunita Patidar, Rajat Pawar, and P. K. Dubey. "FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLET OF PROCHLORPERAZINE MALEATE." International Journal of Pharmaceutical Sciences and Medicine 9, no. 2 (2024): 76–104. http://dx.doi.org/10.47760/ijpsm.2024.v09i02.009.

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In the present work, fast disintegrating tablets of prochlorperazine maleate were designed with a view to enhance patient compliance by effervescent method. Prochlorperazine Maleate, a potent antipsychotic medication with antiemetic properties, holds significance in treating various conditions such as nausea, vomiting, and vertigo. The decision to formulate it into orodispersible tablets aimed to address issues related to patient compliance and convenience, particularly for individuals who experience difficulty swallowing conventional tablets. Formulation F10, enriched with 10% Croscarmellose

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7

Chandan, Nakum*¬ Harpal Makwana Vaishali Karkhanis Hina Bagada. "Stability Indicating Assay Method Development and Validation of HPTLC Method for Estimation of Prochlorperazine maleate in Bulk and Tablet Dosage Form." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1957–72. https://doi.org/10.5281/zenodo.15057985.

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Prochlorperazine maleate is an Antiemetic and Antipsychotic Tranquilizer. It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. An extensive literature surveys reveals that various analytical methods have been reported for the estimation of Prochlorperazine maleate in API and pharmaceutical dosage form. So, it was thought to develop simple, precise, accurate and specific stability indicating HPTLC method for the estimation of Prochlorperazine maleate in API & pharmaceu

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8

Albadry, Ahmed Abdulameer, Wedad K. Ali, and Fouad A. Al-saady. "FORMULATION AND EVALUATION OF PROCHLORPERAZINE MALEATE SUSTAINED RELEASE FLOATING TABLET." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 2 (2017): 89. http://dx.doi.org/10.22159/ijpps.2017v9i2.15665.

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<p><strong>Objective: </strong>The objective of this study was to formulate once daily sustained oral release floating tablet of prochlorperazine maleate, this floating tablet has many advantages like reduction in dosing frequency, increase bioavailability, enhance patient compliance, and improve drug solubility.</p><p><strong>Methods: </strong>The prochlorperazine maleate floating tablets were formulated by using hydrophilic swellable polymer and gas generating agent. In this study, 15 formulas were prepared with many variables in order to achieve an

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9

Tokola, Riitta A. "The Effect of Metoclopramide and Prochlorperazine on the Absorption of Effervescent Paracetamol in Migraine." Cephalalgia 8, no. 3 (1988): 139–47. http://dx.doi.org/10.1046/j.1468-2982.1988.0803113.x.

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Antiemetics modify gastric emptying, a rate-limiting step in drug absorption. The absorption of effervescent paracetamol in water solution was studied in three groups of 10 female patients during acute migraine attacks. Paracetamol was preceded 30 min earlier by a rectal dose of metoclopramide, prochlorperazine maleate, or placebo. Each patient was retested with paracetamol when headache-free. Migraine attacks delayed slightly the absorption of paracetamol solution. Prior administration of rectal prochlorperazine had a minor delaying effect on paracetamol absorption. The peak concentration, th

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10

Shrisunder, Nikhil, Prashant Kumar Dhakad, and Ritu Gilhotra. "Novel RP-HPLC method development and validation for precise quantification of prochlorperazine maleate in pharmaceutical dosage forms." Journal of Applied Pharmaceutical Research 13, no. 1 (2025): 112–22. https://doi.org/10.69857/joapr.v13i1.782.

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Background: Prochlorperazine Maleate, a piperazine phenothiazine derivative, exhibits strong antiemetic and antipsychotic properties. However, existing analytical methods for its quantification in pharmaceutical formulations often face limitations regarding sensitivity, specificity, and accuracy. Many conventional techniques involve extensive sample preparation and prolonged analysis times, making them less feasible for high-throughput quality control. This study developed and validated a novel, precise, and highly sensitive reverse-phase high-performance liquid chromatography (RP-HPLC) method

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Book chapters on the topic "Prochlorperazine maleate"

1

Papich, Mark G. "Prochlorperazine Edisylate, Prochlorperazine Maleate." In Saunders Handbook of Veterinary Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-24485-5.00483-6.

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Papich, Mark G. "Prochlorperazine Edisylate, Prochlorperazine Maleate." In Papich Handbook of Veterinary Drugs. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-70957-6.00453-2.

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Papich, Mark G. "Prochlorperazine Edisylate and Isopropamide Iodide, Prochlorperazine Maleate, and Isopropamide Iodide." In Saunders Handbook of Veterinary Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-24485-5.00484-8.

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Papich, Mark G. "Prochlorperazine Edisylate and Isopropamide Iodide, Prochlorperazine Maleate, and Isopropamide Iodide." In Papich Handbook of Veterinary Drugs. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-70957-6.00452-0.

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