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Journal articles on the topic 'Prodromal services'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Rojnic-Kuzman, M. "Prevention of the first episode of psychosis: What have we reached by 2021?" European Psychiatry 64, S1 (2021): S71. http://dx.doi.org/10.1192/j.eurpsy.2021.221.

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Abstract BodyPrevention of the First Episode of Psychosis: What Have we Reached by 2021? The first episode of psychosis is usually preceded by a prodromal period or stage of psychosis, where early signs of symptoms indicating onset of first episode psychosis (FEP) occur. In the last twenty years, enormous progress was made in the tretment of FEP and subsequently schizophrenia, as the focus of treatment of FEP shifted to this prodromal period with the aim of preventing the first episode of psychosis in people at risk.Treatment for the prodromal stage of psychosis is provided within specialized

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Ajnakina, Olesya, Craig Morgan, Charlotte Gayer-Anderson, et al. "Only a small proportion of patients with first episode psychosis come via prodromal services: a retrospective survey of a large UK mental health programme." BMC Psychiatry 17, no. 1 (2017): 308. https://doi.org/10.1186/s12888-017-1468-y.

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<strong>Background: </strong>Little is known about patients with a first episode of psychosis (FEP) who had first presented to prodromal services with an "at risk mental state" (ARMS) before making the transition to psychosis. We set out to identify the proportion of patients with a FEP who had first presented to prodromal services in the ARMS state, and to compare these FEP patients with FEP patients who did not have prior contact with prodromal services.<strong>Methods: </strong>In this study information on 338 patients aged ≤37 years who presented to mental health services between 2010 and

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Arribas, *Maite, Dominic Oliver, Rashmi Patel, et al. "A TRANSDIAGNOSTIC PRODROME FOR SEVERE MENTAL DISORDERS: AN ELECTRONIC HEALTH RECORD STUDY." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i228—i229. https://doi.org/10.1093/ijnp/pyae059.400.

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Abstract Background Effective prevention of severe mental disorders (SMD) rely on accurate knowledge of the duration and first presentation, time-course and transdiagnosticity of their prodromal stages. This has mostly been investigated in “look-back” studies which have limitations including the use of interviews that are not integrated into clinical practice, small sample sizes and substantial recall biases. Moreover, it is unclear to what extent SMD may display transdiagnostic prodromal symptoms. Aims & Objectives To address these limitations, we take advantage of Electronic Health Recor

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Valmaggia, Lucia R., Majella Byrne, Fern Day, et al. "Duration of untreated psychosis and need for admission in patients who engage with mental health services in the prodromal phase." British Journal of Psychiatry 207, no. 2 (2015): 130–34. http://dx.doi.org/10.1192/bjp.bp.114.150623.

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BackgroundIt is unknown whether prodromal services improve outcomes in those who go on to develop psychosis, and whether these patients are demographically different from the overall first-episode population.AimsTo compare sociodemographic features, duration of untreated psychosis, hospital admission and frequency of compulsory treatment in the first year after the onset of psychosis in patients who present to prodromal services with patients who did not present to services until the first episode of psychosis.MethodWe compared two groups of patients with first-episode psychosis: one who made

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Perry, Alison, Nicholas Tarrier, and Richard Morriss. "Identification of Prodromal Signs and Symptoms and Early Intervention in Manic Depressive Psychosis Patients: A Case Example." Behavioural and Cognitive Psychotherapy 23, no. 4 (1995): 399–409. http://dx.doi.org/10.1017/s1352465800016507.

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Recent research has revealed that relapse in manic depressive psychosis and schizophrenia is preceded by specific prodromal signs and symptoms that include dysphoria, other non-psychotic symptoms and features unique to individual patients. Treatment studies in schizophrenia have shown that early pharmacological intervention during a prodromal phase of psychotic relapse may be effective in the prevention of hospitalization. This paper describes the procedure of prodromal signs identification in manic depressive psychosis and the negotiation of an appropriate plan of action with the mental healt

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Comparelli, A., V. Savoja, G. D. Kotzalidis, et al. "Factor–structure of the Italian version of the Scale Of Prodromal Symptoms (SOPS): a comparison with the English version." Epidemiology and Psychiatric Sciences 20, no. 1 (2011): 45–54. http://dx.doi.org/10.1017/s2045796011000114.

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Aims.The 19-item ‘Scale Of Prodromal Symptoms’ (SOPS) and its semi-structured interview, the Structured Interview for Prodromal Symptoms (SIPS), have been developed to assess prodromes of psychosis. We assessed psychometric properties of the Italian version of the instrument.Methods.We collected socio-demographic and clinical data of 128 people seeking first-time psychiatric help in a large Roman area, either as outpatients at community facilities or as inpatients in psychiatric wards of two general hospitals. Participants were administered the Italian version of the SOPS and the 24-item Brief

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Agius, M., M. Blinc-Pesek, S. Ivezic, et al. "Developing Services for Schizophrenia in Croatia, Slovenia, and Bosnia." European Psychiatry 24, S1 (2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)70495-x.

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Along the coast of the Adriatic, several small projects have developed to improve treatment of patients with Schizophrenia. All these projects have benefited from links with the Department of Psychiatry in Cambridge.In Ljubljana, The Ljubljana Prodrome Project has developed a system of early intervention and treatment which has a strong research arm. It has contributed knowledge about how psychosis develops, and shown that treatment in the prodromal phase of illness gives patients significant advantages.The Assertive Outreach Team in Ljubljana Psychiatric Hospital has reduced readmissions for

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Simmons, Magenta B., and Sarah E. Hetrick. "‘Prodromal’ research and clinical services: The imperative for shared decision-making." Australian & New Zealand Journal of Psychiatry 46, no. 1 (2012): 66. http://dx.doi.org/10.1177/0004867411427813.

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Dvorakova, Monika, and Lucie Kondratova. "S226. DEVELOPMENT OF EARLY DETECTION AND EARLY INTERVENTION SERVICES WITHIN PSYCHIATRIC CARE IN THE CZECH REPUBLIC." Schizophrenia Bulletin 46, Supplement_1 (2020): S125. http://dx.doi.org/10.1093/schbul/sbaa031.292.

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Abstract Background Early Detection (ED) and Early Intervention (EI) are specialized services aiming at early diagnosis and early treatment of psychosis. There are evidence-based effects of ED and EI services that cannot be overlooked, such as early recognition of prodromal symptoms, preventing the adverse effects of untreated psychosis, lowering the risk of hospitalization, and therefore it has become part of the ongoing mental health care reform in the Czech Republic. Methods A total of 12 mental health professionals were trained in order to provide specialised ED and EI services within thre

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Broome, Matthew R., James B. Woolley, Louise C. Johns, et al. "Outreach and support in south London (OASIS): implementation of a clinical service for prodromal psychosis and the at risk mental state." European Psychiatry 20, no. 5-6 (2005): 372–78. http://dx.doi.org/10.1016/j.eurpsy.2005.03.001.

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AbstractBackgroundWhile recent research points to the potential benefits of clinical intervention before the first episode of psychosis, the logistical feasibility of this is unclear.AimsTo assess the feasibility of providing a clinical service for people with prodromal symptoms in an inner city area where engagement with mental health services is generally poor.MethodsFollowing a period of liaison with local agencies to promote the service, referrals were assessed and managed in a primary care setting. Activity of the service was audited over 30 months.ResultsPeople with prodromal symptoms we

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Yung, A. R., H. P. Yuen, G. Berger, et al. "Declining Transition Rate in Ultra High Risk (Prodromal) Services: Dilution or Reduction of Risk?" Schizophrenia Bulletin 33, no. 3 (2007): 673–81. http://dx.doi.org/10.1093/schbul/sbm015.

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Nelson, Barnaby, Magenta B. Simmons, Alison R. Yung, et al. "Identifying the Ultra-High Risk (Prodromal) Population: Evaluation of Training Workshops with Mental Health Services." Australian & New Zealand Journal of Psychiatry 42, no. 3 (2008): 236–43. http://dx.doi.org/10.1080/00048670701827630.

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Calahorro, C. M. Carrillo de Albornoz, M. Guerrero Jiménez, and J. E. Muñoz Negro. "Gynecological consultations during the period of untreated psychosis." European Psychiatry 41, S1 (2017): s813—s814. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1579.

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BackgroundTwenty-one percent of women with first episode of psychosis in the south Granada between 2008 and 2014 went to hospital emergency during the duration of untreated psychosis (DUP) aiming a gynecological consultation caused by psychotic symptoms. Only one in five was referred to mental health services.AimsTo improve difficulties detecting cases during the prodromal phase, we aim to analyze the patient's profile and reasons for consultation and study whether there are variables that facilitate referral to specialist intervention.MethodsA retrospective clinical–cases review of medical hi

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Savic, A., D. Ostojic, T. Jendricko, P. Brecic, and J. Vukojevic. "Prodromal services for at-risk youth and their integration with existing programs: A “modular integration” model." European Psychiatry 64, S1 (2021): S57. http://dx.doi.org/10.1192/j.eurpsy.2021.179.

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Prodromal symptoms may precede onset of the psychotic disorders by years, and while we have instruments for identification of clinical high-risk (CHR), existing predictive models yield low specificity and fail in successfuly predicting transition to psychosis. This, along with the fact that we see a notable decline in transition rates, and the ever-looming lack of resources, means CHR work is still often relegated to research settings. First-episode psychosis (FEP) unit of our institution offers both inpatient and outpatient programs, and while it is common having CHR services emerge from FEP

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Iudici, Antonio, Giulia Alecu, Maria Quarato, and Jessica Neri. "Early Support for People Who Hear Voices: Exploratory Research on Family Medicine Physicians’ Clinical Practice and Beliefs." Behavioral Sciences 14, no. 5 (2024): 357. http://dx.doi.org/10.3390/bs14050357.

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Nowadays the phenomenon of hearing voices represents a very fertile and discussed field of research. In psychological and psychiatric fields, the phenomenon has been described as a normal phenomenon, but also as a prodromal stage and as a symptom of psychosis. Through a qualitative research methodology, the aim was to explore how family medicine physicians configure the phenomenon and its clinical and interactive implications. The present research involved 35 family medicine physicians as figures of primary importance in the approach toward people who start to hear voices. Semi-structured inte

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Camacho, Erica, Leonard Levin, and John Torous. "Smartphone Apps to Support Coordinated Specialty Care for Prodromal and Early Course Schizophrenia Disorders: Systematic Review." Journal of Medical Internet Research 21, no. 11 (2019): e16393. http://dx.doi.org/10.2196/16393.

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Background Demand for mental health services, especially for clinical high-risk and early psychosis, has increased, creating a need for new solutions to increase access to and quality of care. Smartphones and mobile technology are potential tools to support coordinated specialty care for early psychosis, given their potential to augment the six core roles of care: case management and team leadership, recovery-oriented psychotherapy, medication management, support for employment and education, coordination with primary care services, and family education and support. However, the services smart

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De Maio, Valerie J., Ian G. Stiell, George A. Wells, and Daniel W. Spaite. "Cardiac arrest witnessed by emergency medical services personnel: descriptive epidemiology, prodromal symptoms, and predictors of survival." Annals of Emergency Medicine 35, no. 2 (2000): 138–46. http://dx.doi.org/10.1016/s0196-0644(00)70133-8.

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Singh, Swaran P., and Helen L. Fisher. "Early intervention in psychosis: obstacles and opportunities." Advances in Psychiatric Treatment 11, no. 1 (2005): 71–78. http://dx.doi.org/10.1192/apt.11.1.71.

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By focusing therapeutic effort on the early stages of psychotic disorders, effective early intervention should improve short- and long-term outcomes. Strategies include pre-psychotic and prodromal interventions to prevent emergence of psychosis, detecting untreated cases in the community and facilitating recovery in established cases of psychosis. The evidence base for each of these strategies is currently limited, although several international trials are under way. The Department of Health in the UK has announced the intention of setting up 50 early intervention services nationally, several

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Fusar-Poli, P., A. Meneghelli, L. Valmaggia, et al. "Duration of untreated prodromal symptoms and 12-month functional outcome of individuals at risk of psychosis." British Journal of Psychiatry 194, no. 2 (2009): 181–82. http://dx.doi.org/10.1192/bjp.bp.107.047951.

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SummaryIndividuals seeking help from prodromal services may have been experiencing attenuated psychotic features and psychosocial impairments for a long period prior to referral. The effect of an extended duration of these untreated ‘at risk’ symptoms on patients' long-term functional outcome was assessed in a 12-month longitudinal observational study (n=49). A longer duration of untreated ‘at risk’ symptoms was correlated with a reduced improvement in Global Assessment of Functioning scores after 12 months (β=0.375, P=0.008). This effect was independent of age and gender and may have implicat

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Bargiota, S. I., G. Garyfallos, and V. P. Bozikas. "The Status of Early Intervention Services in Greece." European Psychiatry 41, S1 (2017): S728—S729. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1329.

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IntroductionSchizophrenia and other psychotic disorders usually emerge during adolescence and early adulthood deteriorating the lives of young people. As a result, a lot of early intervention services have been developed worldwide.ObjectiveThis study aims to investigate the status of early intervention services in Greece related to similar programs around the world.MethodsThe literature was accessed in order to investigate the status of clinical early intervention services throughout the world. In terms of Greece, a naturalistic research was added to the literature one, since there are not eno

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Giordano, Vincenza, Assunta Guillari, Vincenza Sansone, Maria Catone, and Teresa Rea. "Women Acute Myocardial Infarction—Identifying and Understanding the Gender Gap (WAMy-GAP): A Study Protocol." Healthcare 12, no. 10 (2024): 972. http://dx.doi.org/10.3390/healthcare12100972.

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Barriers to accessing care and misinterpretations of ischemic heart disease symptoms due to lack of awareness contribute to women’s delay in seeking care. Women may delay seeking treatment for up to 3 h or even up to 5 days. They often perceive themselves to be at low risk of cardiovascular disease (CVD) and prioritize family responsibilities or household chores. The causes of this delay are multifactorial and influence the decision-making process, particularly in the pre-hospital phase. The objective of this study protocol is to evaluate prodromal symptoms and identify risk behaviors in women

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Webb, Alastair J. S., Susannah A. E. Brain, Ruth Wood, Simon Rinaldi, and Martin R. Turner. "Seasonal variation in Guillain-Barré syndrome: a systematic review, meta-analysis and Oxfordshire cohort study." Journal of Neurology, Neurosurgery & Psychiatry 86, no. 11 (2014): 1196–201. http://dx.doi.org/10.1136/jnnp-2014-309056.

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IntroductionEvidence for seasonal variation in incidence and subtype of Guillain-Barré syndrome (GBS) is contradictory, but has implications for provision of neurological services and understanding pathogenesis.MethodsWe searched PubMed and EMBASE between inception and January 2014, including all studies reporting seasonal incidence of GBS. We included a retrospective cohort study of patients with GBS at the John Radcliffe Hospital, Oxford 2001–2012 and determined the seasonal variation in GBS incidence and length of stay. The incidence rate ratio (IRR) for winter versus summer was pooled acro

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Calahorro, C. M., M. Guerrero Jiménez, and B. Girala Serrano. "A gender approach in prodromes of psychosis." European Psychiatry 41, S1 (2017): s804. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1555.

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BackgroundOnly 21% of patients included in the South of Granada's First Episodes Program in the year 2014 were women. Studies do not use to focus on sex differences at first-episode samples and it can be masking some relevant variables in this population.AimsIn this exploratory study, we aim to focus on gynaecological consultations during the period of untreated psychosis (DUP) at first episodes of psychosis in women.MethodsA retrospective clinical-cases review of medical histories was made searching for sociodemographic variables, consultations during DUP and psychotic prodromal outcomes.Resu

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Ajnakina, Olesya, Craig Morgan, Sherifat Oduola, et al. "Poster #M218 PATHWAYS TO CARE FOR YOUNG INDIVIDUALS WITH A FIRST-EPISODE PSYCHOSIS IN SOUTH LONDON: USE OF PRODROMAL SERVICES." Schizophrenia Research 153 (April 2014): S269. http://dx.doi.org/10.1016/s0920-9964(14)70768-6.

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Fusar-Poli, P., M. Byrne, S. Badger, L. R. Valmaggia, and P. K. McGuire. "Outreach and support in South London (OASIS), 2001–2011: Ten years of early diagnosis and treatment for young individuals at high clinical risk for psychosis." European Psychiatry 28, no. 5 (2013): 315–26. http://dx.doi.org/10.1016/j.eurpsy.2012.08.002.

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AbstractIntroduction:Prevention of psychosis has become a major objective of modern clinical psychiatry. An increasing number of new services have been established in Europe and in the world. The OASIS team has become an established model where clinical practice and research are fully integrated in the field of preventative interventions in psychosis.Method:Comprehensive analysis of different clinical and service measures describing the 2001–2011 implementation of the OASIS team.Results:Over the last decade, the OASIS team has received a total of 1102 referrals, mostly young males from ethnic

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Vasiliadis, Helen-Maria, Sarah Gagné, Natalia Jozwiak, and Michel Préville. "Gender differences in health service use for mental health reasons in community dwelling older adults with suicidal ideation." International Psychogeriatrics 25, no. 3 (2012): 374–81. http://dx.doi.org/10.1017/s1041610212001895.

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ABSTRACTBackground: To ascertain gender-specific determinants of antidepressant and mental health (MH) service use associated with suicidal ideation.Methods: Data used in this study came from the ESA (Enquête sur la Santé des Aînés) survey carried out in 2005–2008 on a large sample of community-dwelling older adults (n = 2,004). Multivariate logistic regression analyses were carried out.Results: The two-year prevalence of suicidal ideation was 8.4% and 20.3% had persistent suicidal thoughts at one-year follow-up. In males, the prevalence of antidepressant and MH service use in respondents with

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Бережний, О. В., T. O. Білобородова, and І. С. Скарга-Бандурова. "Remote Parkinson's disease monitoring system: from smartphone to cloud platform." ВІСНИК СХІДНОУКРАЇНСЬКОГО НАЦІОНАЛЬНОГО УНІВЕРСИТЕТУ імені Володимира Даля, no. 5(253) (September 5, 2019): 21–25. http://dx.doi.org/10.33216/1998-7927-2019-253-5-21-25.

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Parkinson's disease (PD) is a slowly progressive disorder that affects movement, muscle control, and balance. The earlier treatment can prevent the disease from developing and to prolongate the diseases prodromal phase. In this context, home monitoring services are potentially powerful tools for remote diagnosis and can improve healthcare services. Tremor is the most common symptom of a PD disorder and it has several advantages for continuous PD symptoms monitoring. The developing of solution based on smartphone sensors that allow remote monitoring of the monitored user is present. The connect

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Eady, Nicole, Rory Sheehan, Khadija Rantell, et al. "Impact of cholinesterase inhibitors or memantine on survival in adults with Down syndrome and dementia: clinical cohort study." British Journal of Psychiatry 212, no. 3 (2018): 155–60. http://dx.doi.org/10.1192/bjp.2017.21.

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BackgroundThere is little evidence to guide pharmacological treatment in adults with Down syndrome and Alzheimer's disease.AimsTo investigate the effect of cholinesterase inhibitors or memantine on survival and function in adults with Down syndrome and Alzheimer's disease.MethodThis was a naturalistic longitudinal follow-up of a clinical cohort of 310 people with Down syndrome diagnosed with Alzheimer's disease collected from specialist community services in England.ResultsMedian survival time (5.59 years, 95% CI 4.67–6.67) for those on medication (n = 145, mainly cholinesterase inhibitors) wa

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Mangione, Carol M., Michael J. Barry, Wanda K. Nicholson, et al. "Serologic Screening for Genital Herpes Infection." JAMA 329, no. 6 (2023): 502. http://dx.doi.org/10.1001/jama.2023.0057.

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ImportanceGenital herpes is a common sexually transmitted infection caused by 2 related viruses, herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Infection is lifelong; currently, there is no cure for HSV infection. Antiviral medications may provide clinical benefits to symptomatic persons. Transmission of HSV from a pregnant person to their infant can occur, most commonly during delivery; when genital lesions or prodromal symptoms are present, cesarean delivery can reduce the risk of transmission. Neonatal herpes infection is uncommon yet can result in substantial morbidity an

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Zhang, T. H., H. J. Li, K. A. Woodberry, et al. "Two-year follow-up of a Chinese sample at clinical high risk for psychosis: timeline of symptoms, help-seeking and conversion." Epidemiology and Psychiatric Sciences 26, no. 3 (2016): 287–98. http://dx.doi.org/10.1017/s2045796016000184.

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Background.Chinese psychiatrists have gradually started to focus on those who are deemed to be at ‘clinical high-risk (CHR)’ for psychosis; however, it is still unknown how often those individuals identified as CHR from a different country background than previously studied would transition to psychosis. The objectives of this study are to examine baseline characteristics and the timing of symptom onset, help-seeking, or transition to psychosis over a 2-year period in China.Method.The presence of CHR was determined with the Structured Interview for Prodromal Syndromes (SIPS) at the participant

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Ajnakina, Olesya, Craig Morgan, Charlotte Gayer-Anderson, et al. "35.1 ONLY A SMALL PROPORTION OF PATIENTS WITH FIRST EPISODE PSYCHOSIS COME VIA PRODROMAL SERVICES: A RETROSPECTIVE SURVEY OF A LARGE UK MENTAL HEALTH PROGRAMME." Schizophrenia Bulletin 44, suppl_1 (2018): S58. http://dx.doi.org/10.1093/schbul/sby014.147.

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Bryant, Richard A., Ahmad Bawaneh, Manar Awwad, et al. "Effectiveness of a brief group behavioral intervention for common mental disorders in Syrian refugees in Jordan: A randomized controlled trial." PLOS Medicine 19, no. 3 (2022): e1003949. http://dx.doi.org/10.1371/journal.pmed.1003949.

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Background Common mental disorders are frequently experienced by refugees. This study evaluates the impact of a brief, lay provider delivered group-based psychological intervention [Group Problem Management Plus (gPM+)] on the mental health of refugees in a camp, as well as on parenting behavior and children’s mental health. Methods and findings In this single-blind, parallel, randomized controlled trial, 410 adult Syrian refugees (300 females, 110 males) in Azraq Refugee Camp (Jordan) were identified through screening of psychological distress (≥16 on the Kessler Psychological Distress Scale)

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Khan, Umair, Armughan Ali, Salabat Khan, et al. "Internet of Medical Things–based decision system for automated classification of Alzheimer’s using three-dimensional views of magnetic resonance imaging scans." International Journal of Distributed Sensor Networks 15, no. 3 (2019): 155014771983118. http://dx.doi.org/10.1177/1550147719831186.

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Internet of Medical Things is a smart provision of medical services to patients interacting with the doctors in harmony to uplift healthcare facilities. It enables the automated diagnosis of diseases for patients in remote areas. Alzheimer’s disease is one of the most chronic diseases and the main cause of dementia in human beings. Dementia affects the patient by a process of gradual degeneration of the human brain and results in an inability to perform daily routine tasks and actions. An automated system needs to be developed, to classify the subject with dementia and to determine the prodrom

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Pelizza, Lorenzo, Silvia Azzali, Federica Paterlini, et al. "Screening for psychosis risk among help-seeking adolescents: Application of the Italian version of the 16-item prodromal questionnaire (iPQ-16) in child and adolescent neuropsychiatry services." Early Intervention in Psychiatry 13, no. 4 (2018): 752–60. http://dx.doi.org/10.1111/eip.12554.

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Perez-Sanchez, S., and I. Martin. "Childhood and adolescent schizophrenia and networking." European Psychiatry 67, S1 (2024): S466. http://dx.doi.org/10.1192/j.eurpsy.2024.965.

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IntroductionReviewing the histories of patients with childhood and adolescent schizophrenia, on numerous occasions, traumatic factors with great emotional and social impact are observed, such as situations of mistreatment, abuse and emotional deprivation, where help is requested but resources are scarce and the approach is limited without work in network.Objectives1. Analysis of the consultation pathways in adolescents with severe psychiatric and socio-familial symptoms and the time delay in optimal guidance. 2. Evaluate the services involved. 3. Evaluate the clinical control of treatment with

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Singh, Nishant Kumar, and Dr Vikas Singhal. "Self Identifying Mental Health Status and Get Guidance For Support Using AI." International Research Journal of Computer Science 11, no. 05 (2024): 471–76. http://dx.doi.org/10.26562/irjcs.2024.v1105.07.

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In recent years, an awareness has emerged about the importance of the individual in mental health and treatment. Mental health problems are common among college students around the world; Therefore, identifying at-risk groups will help provide services. Self-diagnosis of mental illness is an important step in recognizing and addressing personal health. Our goal is to develop a screening tool to identify students at risk for mental illness. Students are taught to use assessment tools to distinguish between those at reduced and increased risk of mental illness. Psychological services should be p

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Naismith, Sharon. "Optimising cognition in at-risk older people: A journey of discovery, clinical research and health translation." Journal of the International Neuropsychological Society 29, s1 (2023): 520–21. http://dx.doi.org/10.1017/s1355617723006719.

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AbstractModifiable dementia risk factors such as depression, cardiovascular disease and physical and cognitive activity account for 40-50% of dementia risk and their association with neuropsychological performance is evident in both preclinical and prodromal dementia stages. Over the course of her career, Professor Naismith has examined how modifiable risk factors relate to various aspects of cognition and brain degeneration and how best to treat them. She has led the development of cognitive training programs and clinical trials targeting these risk factors. She has authored more than 350 pap

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Runde, Benjamin S., Ajit Alapati, and Nicolas G. Bazan. "The Optimization of a Natural Language Processing Approach for the Automatic Detection of Alzheimer’s Disease Using GPT Embeddings." Brain Sciences 14, no. 3 (2024): 211. http://dx.doi.org/10.3390/brainsci14030211.

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The development of noninvasive and cost-effective methods of detecting Alzheimer’s disease (AD) is essential for its early prevention and mitigation. We optimize the detection of AD using natural language processing (NLP) of spontaneous speech through the use of audio enhancement techniques and novel transcription methodologies. Specifically, we utilized Boll Spectral Subtraction to improve audio fidelity and created transcriptions using state-of-the-art AI services—locally-based Wav2Vec and Whisper, alongside cloud-based IBM Cloud and Rev AI—evaluating their performance against traditional ma

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Pinho, M., D. Martins, and S. Carvalho. "Cognitive-behavioural therapy role in the prevention of psychosis." European Psychiatry 64, S1 (2021): S498. http://dx.doi.org/10.1192/j.eurpsy.2021.1333.

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IntroductionAbout 30% of individuals in ultra-high risk (UHR) of psychosis develop overt psychosis within 3 years, and about 40% of those who don’t will keep experiencing ongoing attenuated psychotic symptoms and persistent functional disability. During this prodromal period, it’s possible to prevent the transition to a first-episode psychosis.ObjectivesTo conduct a short review of literature on the role of cognitive-behavioural therapy (CBT) in preventing psychosis in ultra-high risk patients.MethodsWe performed a literature search on PUBMED, using the query: “Cognitive Behavioral Therapy” [M

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Fusar-Poli, P., M. Frascarelli, L. Valmaggia, et al. "Antidepressant, antipsychotic and psychological interventions in subjects at high clinical risk for psychosis: OASIS 6-year naturalistic study." Psychological Medicine 45, no. 6 (2014): 1327–39. http://dx.doi.org/10.1017/s003329171400244x.

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Background.Recent randomized controlled trials suggest some efficacy for focused interventions in subjects at high risk (HR) for psychosis. However, treating HR subjects within the real-world setting of prodromal services is hindered by several practical problems that can significantly make an impact on the effect of focused interventions.Method.All subjects referred to Outreach and Support in South London (OASIS) and diagnosed with a HR state in the period 2001–2012 were included (n = 258). Exposure to focused interventions was correlated with sociodemographic and clinical characteristics at

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Kumar, Abhishek, Nihar M. Ranjan, Siddhartha Kr Shah, and Neha Sarkar. "AI-based Interventions for Mental Health: Current Scenario and Future Prospects." Nepal Journal of Neuroscience 21, no. 3 (2001): 20–30. https://doi.org/10.3126/njn.v21i3.67403.

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Modern artificial intelligence (AI), and machine learning in particular, is being used to create prediction, diagnostic, and treatment solutions for mental health care in light of the growing popularity of digital approaches to mental health. Due to their prevalence, depression and anxiety represent the two main mental health conditions that have been the subject of most digital phenotyping research. Chatbots have been used for mental health issues since the 1990s, but their effectiveness remains unknown due to their early stages, though some early studies suggest improvement in anxiety and de

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de Jong, Yvonne, Cornelis L. Mulder, Albert E. Boon, Mathijs Deen, Maarten van ’t Hof, and Mark van der Gaag. "Screening for psychosis risk among adolescents in Child and Adolescent Mental Health Services: a description of the first step with the 16-item version of the Prodromal Questionnaire (PQ-16)." Early Intervention in Psychiatry 12, no. 4 (2016): 669–76. http://dx.doi.org/10.1111/eip.12362.

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Peakman, Georgia, Nishshanka Karunatilake, Mathieu Seynaeve, et al. "Clinical factors associated with progression to dementia in people with late-life depression: a cohort study of patients in secondary care." BMJ Open 10, no. 5 (2020): e035147. http://dx.doi.org/10.1136/bmjopen-2019-035147.

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ObjectivesDepression can be a prodromal feature or a risk factor for dementia. We aimed to investigate which clinical factors in patients with late-life depression are associated with a higher risk of developing dementia and a more rapid conversion.DesignRetrospective cohort study.SettingSouth London and Maudsley NHS Foundation Trust (SLaM) secondary mental healthcare services.ParticipantsThe SLaM Clinical Record Interactive Search was used to retrieve anonymised data on 3659 patients aged 65 years or older who had received a diagnosis of depression in mental health services and had been follo

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Harmata, Barbara, Halina Jędrzejowska-Szypułka, Katarzyna Pawletko, and Joanna Lewin-Kowalik. "Progranulin in neurodegenerative diseases." Postępy Higieny i Medycyny Doświadczalnej 72 (December 11, 2018): 1052–61. http://dx.doi.org/10.5604/01.3001.0012.7836.

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Neurodegenerative diseases as a group of congenital or acquired diseases of the nervous system are currently more common in the aging societies, being one of the most severe diseases faced the healthcare services. Many scientific teams are searching for a better understanding of the mechanisms of these diseases, i.e. their detection, treatment as well as putative prevention methods. Progranulin is one of the twenty-first century discoveries and is a precursor of multifunctional cysteine-rich proteins granulins, which play a crucial role in cell development, cell cycle control, wound healing, i

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Matos, Pedro, Paulo Pinho, Pedro Guedes, et al. "Sarampo: protocolo de atuação num Hospital Português." Revista Portuguesa de Saúde Ocupacional 12 (December 31, 2021): 78–85. http://dx.doi.org/10.31252/rpso.04.12.2021.

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Introduction Measles is a highly contagious infectious disease caused by a paramyxovirus. In the last six decades, the promotion of vaccination against this disease has drastically reduced its incidence. Despite this, in 2016, around seven million new infections were diagnosed. Since healthcare workers have an increased risk of infection, the promotion of vaccination by the Occupational Health Services represents one of the main strategies to consolidate the eradication of this pathology in Portugal. Objectives Review the clinical aspects and prevention measures of Measles with a focus on vacc

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Eisner, Emily, Richard Drake, Richard Emsley, Christine Barrowclough, and Sandra Bucci. "S112. ELUCIDATING THE CHRONOLOGY OF FLUCTUATIONS IN BASIC SYMPTOMS, EARLY SIGNS AND PSYCHOTIC SYMPTOMS IN ESTABLISHED PSYCHOSIS USING REPEATED MEASURES DATA GATHERED USING A SMARTPHONE APP." Schizophrenia Bulletin 46, Supplement_1 (2020): S77. http://dx.doi.org/10.1093/schbul/sbaa031.178.

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Abstract Background Psychosis relapses are common, have profound adverse consequences for patients, and are costly to health services. ‘Early signs’ (e.g. anxiety; insomnia) have been used to predict relapse, in the hope of prevention or mitigation, with moderate sensitivity and specificity. Recent studies have provided preliminary prospective evidence that assessing ‘basic symptoms’ (e.g. vivid colour vision; disturbances in expressive speech) in addition to conventional early signs improves relapse prediction. Basic symptoms are assumed to be one of the earliest, most basic subjective expres

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Martinez, Jairo E., Yamile Bocanegra, Ana Baena, et al. "26 Religious Stress Coping, Memory, and Markers of Brain Pathology in Individuals with Autosomal Dominant Alzheimer’s Disease from the Colombia-Boston Biomarker Study." Journal of the International Neuropsychological Society 29, s1 (2023): 236–37. http://dx.doi.org/10.1017/s1355617723003454.

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Objective:High levels of stress may increase risk for Alzheimer’s disease (AD) dementia. Religious coping practices to deal with stress (i.e., prayer, having faith, attending religious services) may reduce risk of dementia. Studying religious stress coping in cognitively unimpaired individuals with autosomal-dominant AD (ADAD), who will develop dementia later in life, may inform us about the role of religious coping in modifying the clinical trajectory from preclinical to clinical stages of the disease. We examined religious stress coping in cognitively unimpaired mutation carriers from the wo

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Murphy, Brendan P., and Warrick J. Brewer. "Early intervention in psychosis: strengths and limitations of services." Advances in Psychiatric Treatment 17, no. 6 (2011): 401–7. http://dx.doi.org/10.1192/apt.bp.110.008573.

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SummaryEarly intervention services were established on the basis of a number of fundamental principles, including the notions that intervening in the early stages of psychosis alters illness trajectory and prognosis, that multicomponent interventions promote psychosocial recovery and reduce iatrogenic damage, and that early targeting of non-responders reduces treatment resistance. There is growing evidence of the benefits of specialised early intervention services. These include improved clinical, social and vocational outcomes, reduced in-patient stays and better engagement. Early interventio

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Kounali, Daphne, Sarah Sullivan, Jon Heron, et al. "M110. PREDICTING RISK OF PSYCHOSIS IN A GENERAL POPULATION SAMPLE." Schizophrenia Bulletin 46, Supplement_1 (2020): S176—S177. http://dx.doi.org/10.1093/schbul/sbaa030.422.

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Abstract Background At present clinical high-risk states for psychosis are determined by specialist mental health services using clinical tools such as the CAARMS, which largely rely on the detection of attenuated psychotic symptoms. However, the positive predictive value (PPV) of the CAARMS for transition to psychosis is only 25% in help seeking populations and as low as 5% in general population, non-help seeking samples. There is therefore a clear need to improve the prediction of psychotic disorder using other (non-symptom related) markers of risk. Our aim was to derive a risk prediction to

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Duran i López, Irema, and Rocío Juliá-Sanchis. "Continuidad de cuidados en menores con problemas neuropsiquiátricos: a propósito de un caso clínico." Nº 14 septiembre 2021, no. 14 (2021): 12–21. http://dx.doi.org/10.35761/reesme.2021.14.03.

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Resumen Introducción: Hasta un tercio de los menores y adolescentes presentan algún tipo de trastorno mental, siendo el trastorno con déficit de atención e hiperactividad uno de los más prevalentes. Dicho trastorno aumenta el riesgo de comorbilidades neuropsiquiátricas que alteran el funcionamiento académico y social, dificultando la escolarización ordinaria ante la falta de recursos y programasde atención específicos. Objetivo: Evidenciar la falta de continuidad de cuidados integrales en menores con problemas neuropsiquiátricos y proponer un plan de cuidados: a propósito de un caso. Descripci

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