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Journal articles on the topic 'Producer-producer interaction'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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1

Nahuis, Roel, Ellen H. M. Moors, and Ruud E. H. M. Smits. "User producer interaction in context." Technological Forecasting and Social Change 79, no. 6 (2012): 1121–34. http://dx.doi.org/10.1016/j.techfore.2012.01.005.

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2

Heiskanen, Eva, and Raimo Lovio. "User−Producer Interaction in Housing Energy Innovations." Journal of Industrial Ecology 14, no. 1 (2010): 91–102. http://dx.doi.org/10.1111/j.1530-9290.2009.00196.x.

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3

Bower, D. Jane. "User-producer Interaction and the Case of Biomedical Innovation." Journal of Industry Studies 3, no. 1 (1996): 21–34. http://dx.doi.org/10.1080/13662719600000002.

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4

Dong, Hongmei, and Lili Huang. "A Study on the Co-Agglomeration of Manufacturing Industry and Producer Services in Heilongjiang Province." E3S Web of Conferences 292 (2021): 03005. http://dx.doi.org/10.1051/e3sconf/202129203005.

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Manufacturing industry and producer services are two important categories of industrial development in Heilongjiang Province. The co-agglomeration development is conducive to improving the interaction level between them and promoting the development of regional industrial cluster. Based on the relevant data of manufacturing and producer services in Heilongjiang Province, this paper uses the location quotient model to estimate the co-agglomeration of manufacturing and producer services. Heilongjiang Province should promote the integrated development of producer services and manufacturing industry, so as to realize the transformation and upgrading of traditional manufacturing industry in the old industrial base.

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MOORS, E. H. M., W. P. C. BOON, R. NAHUIS, and R. L. J. VANDEBERG. "USER-PRODUCER INTERACTIONS IN EMERGING PHARMACEUTICAL AND FOOD INNOVATIONS." International Journal of Innovation Management 12, no. 03 (2008): 459–87. http://dx.doi.org/10.1142/s1363919608001984.

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In order to study user-producer interaction (UPI) in emerging pharmaceutical and food innovation processes, a classification of user involvement has been developed, including a contextualised view on UPIs. Case studies are performed on two types of UPI: demand articulation in intermediary organisations and interactive learning in consortia, in the pharmaceutical and food sector, respectively.Regarding demand articulation processes, articulation of problems, needs, demands and expectations through agenda-setting practices is important. Expression and evaluation of demands with other factors leads to moblization of creative potential of prospective users and facilitation of emerging innovation processes.Regarding interactive learning, geographical, organisational, regulatory and cognitive proximity conditions could facilitate structures for emerging technology development, and codes and networks for frequent interaction between complementary stakeholders. Demands, concerns and opportunities are articulated by shared visions. Organised UPIs via intermediary user organisations or consortia seem to be the important tools for demand articulation and interactive learning involving patient organisations, researchers and private and public organisations.

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Medvedev, Alexey, Ivan Kislyakov, Yevgheniya Prokopenko, Maria Semenkina, and Kristina Brester. "Automated Toolkit for Encouraging a Producer to Use Innovative Technologies in Environmentally Oriented Economic Development of Mining Regions." E3S Web of Conferences 105 (2019): 03020. http://dx.doi.org/10.1051/e3sconf/201910503020.

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The automated toolkit for assessing environmental and investment attractiveness of a mining region and the results of its application are discussed in the article. This toolkit includes the optimization mathematical model, the algorithms for the interaction between a regional control center and a producer within the territory, as well as the automated software package for their analysis. The use of the optimization mathematical model makes it possible to take into account the maximum economic potential of a producer, which determines, respectively, a mining region’s environment pollution potential. Accounting for environmental risks will allow the control center or other decision makers to identify not only the optimal pattern of eco-economic interaction in the region, but also reflect changes in the environmental and investment climate as a combination of economic potential and involved risks. The model and the algorithms of interaction between a regional control center and a producer, as well as the results of their numerical analysis given in this paper, allow considering this toolkit as an effective decision support tool aimed at improving environmental and investment attractiveness of a mining region by encouraging a producer to use the best available technologies and conserve the natural environment.

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7

Li, Bingqiang. "The interaction of clusters between manufacturing and producer services in China." Economic Research-Ekonomska Istraživanja 30, no. 1 (2017): 1427–42. http://dx.doi.org/10.1080/1331677x.2017.1355253.

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8

HASU, MERVI, and YRJÖ ENGESTRÖM. "Measurement in action: an activity-theoretical perspective on producer–user interaction." International Journal of Human-Computer Studies 53, no. 1 (2000): 61–89. http://dx.doi.org/10.1006/ijhc.2000.0375.

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9

van Rijnsoever, Frank J., Jan Faber, Marnix L. J. Brinkman, and Marijn A. van Weele. "User-producer interaction in Web site development: Motives, modes, and misfits." Journal of the American Society for Information Science and Technology 61, no. 3 (2010): 495–504. http://dx.doi.org/10.1002/asi.21277.

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10

CHIVERS, W. J., W. GLADSTONE, and R. D. HERBERT. "SPATIAL EFFECTS IN AN INDIVIDUAL-BASED MODEL OF PRODUCER-HERBIVORE INTERACTION." Natural Resource Modeling 21, no. 1 (2008): 72–92. http://dx.doi.org/10.1111/j.1939-7445.2008.00013.x.

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11

Beise-Zee, Rian, and Christian Rammer. "Local User-Producer Interaction in Innovation and Export Performance of Firms." Small Business Economics 27, no. 2-3 (2006): 207–22. http://dx.doi.org/10.1007/s11187-006-0013-z.

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12

Kalashnikov, Vitaliy, Daniel Flores Curiel, and Vyacheslav V. Kalashnikov. "Production Competition in Electricity Sector: Social Welfare vs. Managerial Incentives in a Partially Regulated Duopoly." Journal of Advanced Computational Intelligence and Intelligent Informatics 21, no. 6 (2017): 1034–39. http://dx.doi.org/10.20965/jaciii.2017.p1034.

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We study production competition between two electricity producers, where one of them is subject to a nationalization decision and the other is a private producer that chooses managerial incentives to counter governmental actions. The government wants to maximize a modified form of social welfare and chooses partial nationalization, which still has a serious impact on the rival private producer. We find, that by offering managerial incentives the private producer recovers its lost profit and induces even less nationalization. We also find that such equilibrium might produce the same level of social welfare than one without incentives.

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13

Lanchier, N. "Stochastic Spatial Model of Producer-Consumer Systems on the Lattice." Advances in Applied Probability 45, no. 04 (2013): 1157–81. http://dx.doi.org/10.1017/s0001867800006819.

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The objective of this paper is to give a rigorous analysis of a stochastic spatial model of producer-consumer systems that has been recently introduced by Kang and the author to understand the role of space in ecological communities in which individuals compete for resources. Each point of the square lattice is occupied by an individual which is characterized by one of two possible types, and updates its type in continuous time at rate 1. Each individual being thought of as a producer and consumer of resources, the new type at each update is chosen at random from a certain interaction neighborhood according to probabilities proportional to the ability of the neighbors to consume the resource produced by the individual to be updated. In addition to giving a complete qualitative picture of the phase diagram of the spatial model, our results indicate that the nonspatial deterministic mean-field approximation of the stochastic process fails to describe the behavior of the system in the presence of local interactions. In particular, we prove that, in the parameter region where the nonspatial model displays bistability, there is a dominant type that wins regardless of its initial density in the spatial model, and that the inclusion of space also translates into a significant reduction of the parameter region where both types coexist.

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Lanchier, N. "Stochastic Spatial Model of Producer-Consumer Systems on the Lattice." Advances in Applied Probability 45, no. 4 (2013): 1157–81. http://dx.doi.org/10.1239/aap/1386857862.

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The objective of this paper is to give a rigorous analysis of a stochastic spatial model of producer-consumer systems that has been recently introduced by Kang and the author to understand the role of space in ecological communities in which individuals compete for resources. Each point of the square lattice is occupied by an individual which is characterized by one of two possible types, and updates its type in continuous time at rate 1. Each individual being thought of as a producer and consumer of resources, the new type at each update is chosen at random from a certain interaction neighborhood according to probabilities proportional to the ability of the neighbors to consume the resource produced by the individual to be updated. In addition to giving a complete qualitative picture of the phase diagram of the spatial model, our results indicate that the nonspatial deterministic mean-field approximation of the stochastic process fails to describe the behavior of the system in the presence of local interactions. In particular, we prove that, in the parameter region where the nonspatial model displays bistability, there is a dominant type that wins regardless of its initial density in the spatial model, and that the inclusion of space also translates into a significant reduction of the parameter region where both types coexist.

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15

Krasovskii, Andrey, Nikolay Khabarov, Ruben Lubowski, and Michael Obersteiner. "Flexible Options for Greenhouse Gas-Emitting Energy Producer." Energies 12, no. 19 (2019): 3792. http://dx.doi.org/10.3390/en12193792.

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The reduction of emissions from deforestation and forest degradation (REDD) constitutes part of the international climate agreements and contributes to the Sustainable Development Goals. This research is motivated by the risks associated with the future C O 2 price uncertainty in the context of the offsetting of carbon emissions by regulated entities. The research asked whether it is possible to reduce these financial risks. In this study, we consider the bilateral interaction of a REDD supplier and a greenhouse gas (GHG)-emitting energy producer in an incomplete emission offsets market. Within this setting, we explore an innovative financial instrument—flobsion—a flexible option with benefit-sharing. For the quantitative assessment, we used a research method based on a two-stage stochastic technological portfolio optimization model established in earlier studies. First, we obtain an important result that the availability of REDD offsets does not increase the optimal emissions of the electricity producer under any future C O 2 price realization. Moreover, addressing concerns about a possible “crowding–out” effect of REDD-based offsets, we demonstrate that the emissions and offsetting cost will decrease and increase, respectively. Second, we demonstrate the flexibility of the proposed instrument by analyzing flobsion contracts with respect to the benefit-sharing ratio and strike price within the risk-adjusted supply and demand framework. Finally, we perform a sensitivity analysis with respect to C O 2 price distributions and the opportunity costs of the forest owner supplying REDD offsets. Our results show that flobsion’s flexibility has advantages compared to a standard option, which can help GHG-emitting energy producers with managing their compliance risks, while at the same time facilitating the development of REDD programs. In this study we limited our analysis to the case of the same C O 2 price distributions foreseen by both parties; the flobsion pricing under asymmetric information could be considered in the future.

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16

Cvetnić, Zdenka, and Stjepan Pepeljnjak. "Interaction Between Certain Moulds and Aflatoxin B1 Producer Aspergillus Flavus NRRL 3251." Archives of Industrial Hygiene and Toxicology 58, no. 4 (2007): 429–34. http://dx.doi.org/10.2478/v10004-007-0036-0.

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Interaction Between Certain Moulds and Aflatoxin B1ProducerAspergillus FlavusNRRL 3251The objective of this study was to evaluate biotic interaction between some mould species and active producer of aflatoxin B1Aspergillus flavusNRRL 3251, co-cultured in yeast-extract sucrose (YES) broth. Twenty-five mould strains ofAlternariaspp.,Cladosporiumspp.,Mucorspp.,A. flavusandA. niger, used as biocompetitive agents, were isolated from outdoor and indoor airborne fungi, scrapings of mouldy household walls, and from stored and post-harvest maize. Aflatoxin B1was extracted from mould biomasses with chloroform and detected using the multitoxin TLC method. The results confirm antagonistic interaction between all strains tested. WithAlternariaspp. andCladosporiumspp., aflatoxin B1production decreased 100 %, compared to detection in a single culture ofA. flavusNRRL 3251 (Cmean=18.7 μg mL-1). In mixed cultures withMucorspp., aflatoxinB1levels dropped to (5.6-9.3) μg mL-1, and the inhibition was from 50 % to 70 %. Four of five aflatoxin non-producing strains ofA. flavusinterfered with aflatoxin production in mixed culture, and reduced AFB1productivity by 100 %. One strain showed a lower efficacy in inhibiting AFB1production (80 %) with a detectable amount of AFB13.7 μg mL-1when compared to control. A decrease in toxin production was also observed in dual cultivation withA. nigerstrains. It resulted in 100 % reduction in three strains), 90 % reduction in one strain (Cmean=1.9 μg mL-1) and 80 % reduction in one strain (Cmean=3.7 μg mL-1) inhibition.

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17

Esparza, Adrian, and Andrew J. Krmenec. "The Spatial Extent of Producer Service Markets: Hierarchical Models of Interaction Revisited." Papers in Regional Science 75, no. 3 (2005): 375–95. http://dx.doi.org/10.1111/j.1435-5597.1996.tb00670.x.

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18

Esparza, Adrian, and Andrew J. Krmenec. "The spatial extent of producer service markets: Hierarchical models of interaction revisited." Papers in Regional Science 75, no. 3 (1996): 375–95. http://dx.doi.org/10.1007/bf02406759.

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19

Grasseni, Cristina. "Re-localizing Milk and Cheese." Gastronomica 14, no. 4 (2014): 34–43. http://dx.doi.org/10.1525/gfc.2014.14.4.34.

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The reinvention of food is also a matter of re-localization. This means rethinking food chains in terms of their spatiality. This article deals with milk and cheese and their reinvention in Italy through two distinct, even opposing, strategies: automatization and face-to-face involvement of critical consumers with producers. Each of these strategies associates trust with different spatial arrangements. In the case of raw milk automated distributors (locally named the equivalent of “milk ATMs”), trust is associated with the short distance to the raw milk producer, with whom, however, there is no direct interaction. In the case of food activist circles, notably Italy’s Solidarity Purchase Groups or GAS, trust lies in actual interaction with the producer. This acquires a specific meaning in a culture that assigns added social significance to the act of food provisioning and cultivates plural practices of social interactions that are mediated through food.

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20

Ram, Zvi, Kenneth W. Culver, Stuart Walbridge, Joseph A. Frank, R. Michael Blaese, and Edward H. Oldfield. "Toxicity studies of retroviral-mediated gene transfer for the treatment of brain tumors." Journal of Neurosurgery 79, no. 3 (1993): 400–407. http://dx.doi.org/10.3171/jns.1993.79.3.0400.

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✓ Retroviral-mediated transfer of the herpes simplex virus thymidine kinase (HSVtk) gene into malignant tumors confers drug susceptibility to the antiviral drug ganciclovir. The authors have recently shown that in situ transduction of the rat 9L brain tumor following HSVtk-producer cell implantation led to tumor regression after ganciclovir administration in treated rats. A wide spectrum of potential adverse effects may, however, be associated with the application of this approach to treat brain tumors, including dissemination of the retroviral vector to nontumoral tissues within or outside the central nervous system, proliferation of the injected murine vector-producer cells at the injection site, immune-mediated responses to the implantation of xenogeneic cells, and damage to the brain from toxic by-products of the HSVtk-ganciclovir interaction. These possibilities were investigated using intracerebral and systemic injections of retroviral vector-producer cells carrying the HSVtk or the lacZ gene in mice, rats, and nonhuman primates. Using the lacZ gene as a reporter gene, no evidence of β-galactosidase activity consistent with vector transduction was detected in any major body organ in the treated mice or rats. Similarly, the HSVtk gene transfer did not result in toxicity, with or without ganciclovir administration. In studies using rat and monkey models, no proliferation of the vector-producer cells occurred after intracerebral injection. Vector-producer cell survival was limited to 7 to 14 days. High-dose steroid therapy did not appear to extend the survival of these xenogeneic cells in rats. No significant inflammatory response was observed in the meninges or brain parenchyma. Endothelial cells were occasionally transduced in brain capillaries adjacent to the injected site of the vector-producer cells. Injection of producer cells into brain tissue elicited mild edema and reactive gliosis surrounding the injection site, which were probably the cause of a transient toxic response arising 4 to 5 days following injection of the producer cells; short-term administration of dexamethasone eliminated that response. No neurological deficits were observed in the rats or primates treated with the HSVtk vector-producer cells, with or without ganciclovir. In primates injected with producer cells, magnetic resonance imaging before, during, and after ganciclovir administration showed minimal and localized breakdown of the blood-brain barrier without significant edema or mass effect. Similarly, histological examination of the monkeys' brains showed no damage to neurons, astroglia, or myelin. Long-term clinical (> 9 months) and radiological (3 months) assessment of the primates has revealed no evidence of toxicity. The results of these studies indicate that intratumoral implantation of HSVtk-producer cells can be attempted for the treatment of brain tumors, without anticipating significant adverse toxicity to normal brain or remote proliferating tissues.

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Mikhailova, Olga. "Adoption and implementation of new technologies in hospitals: a network perspective." IMP Journal 12, no. 2 (2018): 368–91. http://dx.doi.org/10.1108/imp-05-2017-0027.

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Purpose The purpose of this paper is to address challenges and opportunities that smaller hospitals with limited resources may face when they are adopting and implementing innovative technologies. Design/methodology/approach Based on a single case study with interviews and document analysis, this paper focuses on the recombination of resources, actors and activities during the process of technology adoption and implementation at a Danish hospital. Theoretically, it takes an interaction perspective for exploring the interplay between inner and outer networking during the innovation processes. Findings This study illustrates how the adoption and implementation of advanced medical technology requires significant investment, which is particularly burdensome for smaller hospitals. Constrained by limited resources, they have to develop creative combinations of resources through negotiation and embrace collaborative approaches to join and sustain themselves in the user-producer network. Originality/value This paper contributes to the innovation field by suggesting ways in which practitioners at smaller hospitals can align with technology providers’ strategies and succeed by positioning their hospitals in relation to extended user-producer networks. This study further emphasizes the necessity of a broader discussion regarding the importance of user-producer interactions during innovation processes in health care settings.

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22

Kong, Lingyi, and Xiao Liang. "Research on the Interaction between Producer Services and Manufacturing Industry in Shaanxi Province." American Journal of Industrial and Business Management 08, no. 05 (2018): 1277–89. http://dx.doi.org/10.4236/ajibm.2018.85087.

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23

Slot, Mijke. "Exploring user-producer interaction in an online community: the case of Habbo Hotel." International Journal of Web Based Communities 5, no. 1 (2009): 33. http://dx.doi.org/10.1504/ijwbc.2009.021560.

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24

Lázár, Attila N., Andrew J. Wade, and Brian Moss. "Modelling Primary Producer Interaction and Composition: an Example of a UK Lowland River." Environmental Modeling & Assessment 21, no. 1 (2015): 125–48. http://dx.doi.org/10.1007/s10666-015-9473-3.

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25

LYON, WANDA J., DENNIS G. OLSON, and ELSA A. MURANO. "Isolation and Purification of Enterocin EL1, a Bacteriocin Produced by a Strain of Enterococcus faecium†." Journal of Food Protection 58, no. 8 (1995): 890–98. http://dx.doi.org/10.4315/0362-028x-58.8.890.

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A meat isolate, identified as Enterococcus faecium L1, was found to produce a bacteriocin designated enterocin EL1 Enterocin EL1 was active against a narrow spectrum of microorganisms, inhibiting all tested strains of Listeria. Identification of the producer strain was determined phenotypically by biochemical and morphological tests. Enterocin EL1 was heat stable, sensitive to several proteolytic enzymes, and stable from pH 2 to 11. Adsorption of the bacteriocin to producer cells was dependent on ionic interaction of the bacteriocin and the cell surface at various pHs. By changing the pH of the extraction buffer, enterocin EL1 was extracted from E. faecium L1 cells in a concentrated form. Enterocin EL1 isolated by cell extraction was resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis as a protein with an approximate molecular weight of 2,300. Partially purified enterocin EL1 added to sensitive cells of Listeria ivanovii was bactericidal; however, the bacteriocin did not inhibit the producer strain L1.

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26

Deodato, Joseph. "The patron as producer: libraries, web 2.0, and participatory culture." Journal of Documentation 70, no. 5 (2014): 734–58. http://dx.doi.org/10.1108/jd-10-2012-0127.

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Purpose – The purpose of this paper is to offer a theoretical framework for applying Web 2.0 technologies and design principles to the development of participatory cultures within libraries. A participatory culture is one that focusses on facilitating interaction and the creation of content by users rather than the consumption of content created or compiled by experts. Design/methodology/approach – This study is a literature-based theoretical analysis that explores the role of libraries as agents of cultural hegemony and techniques for developing socially responsible library praxis. It combines insights from a variety of discourses including Western Marxist theories of hegemony, critical theories of library and information science, professional literature regarding “Library 2.0” service models, and media studies theories of participatory culture. Findings – Libraries do not just organize knowledge; they construct it. Furthermore, these constructions tend to reinforce dominant discourses while marginalizing others. By adopting participatory technologies and design principles, libraries can support greater diversity of expression and create spaces for marginalized discourses. Practical implications – This paper offers suggestions for applying principles of participatory culture to the design of library services such as collection development, cataloging and classification, reference, instruction, and institutional repositories. Originality/value – This paper provides a conceptual framework for understanding and evaluating the significance of Web 2.0 for library and information science by applying theoretical perspectives from other disciplines.

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Tamayo-Belda, Miguel, Juan José Vargas-Guerrero, Keila Martín-Betancor, et al. "Understanding nanoplastic toxicity and their interaction with engineered cationic nanopolymers in microalgae by physiological and proteomic approaches." Environmental Science: Nano 8, no. 8 (2021): 2277–96. http://dx.doi.org/10.1039/d1en00284h.

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This study reveals novel mechanisms and potential biomarkers of nanopolymer toxicity (polystyrene nanoplastics and PAMAM dendrimers) singly and in combination in a relevant aquatic primary producer, essential for sustaining the food chain.

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Simpson, I. H., G. Kay, and W. K. Mason. "The SGS Regional Producer Network: a successful application of interactive participation." Australian Journal of Experimental Agriculture 43, no. 8 (2003): 673. http://dx.doi.org/10.1071/ea02190.

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The Regional Producer Network (RPN) functioned across southern Australia as the primary delivery mechanism of the Sustainable Grazing Systems (SGS) Program for 5 years (1996–2001) and the Harvest Year (2001–2002). It consisted of a network of Producer Committees that provided on-ground organisation to coordinate extension activities in the 11 SGS regions. The operation of the RPN was modelled on a participation mode called Interactive Participation. The main objective was to support the adoption of a large-scale practice change in the high rainfall zone towards more productive, profitable and sustainable grazing systems. Strong producer leadership developed and information exchange improved to achieve a high level of impact on management skills among those producers motivated to improve their grazing operations. The characteristics of Interactive Participation were incorporated into the processes and operation of the RPN. Defined and structured methodologies were used for collective and context-specific learning within the framework of a producer network that encouraged interaction. The strength of Interactive Participation was that producers saw participation as a right and not just a means to achieve the program goal. Each region took control over local decisions including the allocation of available resources. The process engaged all sectors of the program (producers, researchers, management and funders). The experiential extension procedures used systematic and structured learning activities to support producers who were committed to learning, on-farm change and improvement to grazing management. In developing a coordinated approach to their operation, the Producer Committees engaged grazing industry researchers, public and private extension practitioners and community groups. This collaboration strengthened local organisations and developed community confidence in the grazing industries.

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Ritter, Caroline, Herman W. Barkema, and Cindy L. Adams. "Action cameras and the Roter interaction analysis system to assess veterinarian-producer interactions in a dairy setting." Veterinary Record 182, no. 8 (2017): 227. http://dx.doi.org/10.1136/vr.104423.

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Herd health and production management (HH&PM) are critical aspects of production animal veterinary practice; therefore, dairy veterinarians need to effectively deliver these services. However, limited research that can inform veterinary education has been conducted to characterise these farm visits. The aim of the present study was to assess the applicability of action cameras (eg, GoPro cameras) worn by veterinarians to provide on-farm recordings, and the suitability of these recordings for comprehensive communication analyses. Seven veterinarians each recorded three dairy HH&PM visits. Recordings were analysed using the Roter interaction analysis system (RIAS), which has been used to evaluate medical conversations in human and companion animal contexts, and provided insights regarding the importance of effective clinical communication. However, the RIAS has never been used in a production animal environment. Results of this pilot study indicate that on-farm recordings were suitable for RIAS coding. Dairy practitioners use a substantial amount of talk allocated to relationship-building and farmer education but that communication patterns of the same veterinarian vary considerably between farm visits. Consecutive studies using this method will provide observational data for research purposes and promise to aid in the improvement of veterinary education through identification of communication priorities and gaps in dairy advisory discussions.

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30

Foster, Christopher, and Richard Heeks. "Nurturing user–producer interaction: inclusive innovation flows in a low-income mobile phone market." Innovation and Development 4, no. 2 (2014): 221–37. http://dx.doi.org/10.1080/2157930x.2014.921353.

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Sokolskaja, Elena, David M. Sayah, and Jeremy Luban. "Target Cell Cyclophilin A Modulates Human Immunodeficiency Virus Type 1 Infectivity." Journal of Virology 78, no. 23 (2004): 12800–12808. http://dx.doi.org/10.1128/jvi.78.23.12800-12808.2004.

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ABSTRACT The peptidyl-prolyl isomerase cyclophilin A (CypA) increases the kinetics by which human immunodeficiency virus type 1 (HIV-1) spreads in tissue culture. This was conclusively demonstrated by gene targeting in human CD4+ T cells, but the role of CypA in HIV-1 replication remains unknown. Though CypA binds to mature HIV-1 capsid protein (CA), it is also incorporated into nascent HIV-1 virions via interaction with the CA domain of the Gag polyprotein. These findings raised the possibility that CypA might act at multiple steps of the retroviral life cycle. Disruption of the CA-CypA interaction, either by the competitive inhibitor cyclosporine (CsA) or by mutation of CA residue G89 or P90, suggested that producer cell CypA was required for full virion infectivity. However, recent studies indicate that CypA within the target cell regulates HIV-1 infectivity by modulating Ref1- or Lv1-mediated restriction. To examine the relative contribution to HIV-1 replication of producer cell CypA and target cell CypA, we exploited multiple tools that disrupt the HIV-1 CA-CypA interaction. These tools included the drugs CsA, MeIle4-CsA, and Sanglifehrin; CA mutants exhibiting decreased affinity for CypA or altered CypA dependence; HeLa cells with CypA knockdown by RNA interference; and Jurkat T cells homozygous for a deletion of the gene encoding CypA. Our results clearly demonstrate that target cell CypA, and not producer cell CypA, is important for HIV-1 CA-mediated function. Inhibition of HIV-1 infectivity resulting from virion production in the presence of CsA occurs independently of the CA-CypA interaction or even of CypA.

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Shaymukhametova, Liudmila N. "The Pianist-Producer. Interpretation and Transcription in the Work with Beginning Pianists." ICONI, no. 3 (2019): 77–89. http://dx.doi.org/10.33779/2658-4824.2019.3.077-089.

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One of the main criteria of professional performance by the musician of compositions established in the repertoire is considered to be a concise interpretation of the musical text with rendering all the markings made by the editor and the composer. A steadfast tradition has been created of application in pedagogical practice of interpretation by other musicians and an authoritarian approach to learning. However, if such demands are to be considered to be admissible, they cannot be applied to all the styles and genres. The pianist’s interaction with the musical text has been historically determined by two forms which have evolved in the practice of music-making itself. For example, in Baroque music the ensemble form of music-making, which predominated in it, presumed a variant-type unfolding of the keyboard musical text in various performance versions and ensembles. The Baroque tradition is distinct for its active transformation of the musical material and its improvisatory manner in the work with the primary musical source, and it presumes an active incorporation of transcriptions, adaptations, elaborations, arrangements and variations on the original musical text. The second form, which is the soloist variety, regulated by the composer’s precise notation, is designed for interpretation of the music and its performance in concerts. It is particularly the second type, characteristic for the later Classical-Romantic tradition, which is used in teaching, hence the rules of interaction with the musical text are transferred by pedagogues to the other type of musical text, namely, the Baroque variety, as well. The primary musical source contains numerous possibilities for the variant-type replication and creation of performance scenarios both in the ensemble and solo forms. By applying both forms of performing music, transcription and interpretation, the pedagogue would enhance the revival of the traditions of a creative attitude towards the musical text. The article shows examples of work with beginning pianists in a problem-based situation which may be called the role game of “Pianist- Producer.”

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Wubben, E. F. M., M. Fondse, and S. Pascucci. "The importance of stakeholder-initiatives for business models in short food supply chains: the case of the Netherlands." Journal on Chain and Network Science 13, no. 2 (2013): 139–49. http://dx.doi.org/10.3920/jcns2013.1004.

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While the interest in Short Food Supply Chains (SFSCs) is growing, we still await management studies that explore the impact of stakeholders of SFSCs in substantial numbers. This article investigates the differences in the business models of SFSCs that may be attributed to the initiator-stakeholder, interacting with other stakeholders. Essential to business models are the value proposition, value creation and value capture, but it is the ambition of the initiator-stakeholder that starts a SFSC. Initiator-stakeholders of 57 SFSCs were interviewed on a combination of both multiple choice and open questions. The data converges on three categories of business models. First and foremost, a large majority of SFSCs is driven by the aim of the initiator-stakeholder to increase economic viability, uses the market as governance structure, resulting in profit margins likely to be above margins in conventional business. Two other categories of business models of SFSCs group around the theme of producer-support, and, producer-consumer interaction, respectively.

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Hennion, Antoine. "An Intermediary Between Production and Consumption: The Producer of Popular Music." Science, Technology, & Human Values 14, no. 4 (1989): 400–424. http://dx.doi.org/10.1177/016224398901400405.

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Booth, Ginger. "Gecko: A Continuous 2D World for Ecological Modeling." Artificial Life 3, no. 3 (1997): 147–63. http://dx.doi.org/10.1162/artl.1997.3.3.147.

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An individual-based simulation system, named Gecko, is presented for modeling multiple species at multiple trophic levels, on a spatially explicit, continuous two-dimensional landscape. Biologically motivated rules are specified at an individual level, and resulting behaviors are observed at an ecosystem level. Individuals are represented by circles with free range on a resource-producing plane. These circles grow allometrically with biomass of fixed resources. Resource acquisition behaviors include competition by area overlap for producers, and movement based on perception and intent. Individual-level energetics are explicitly modeled with inefficient assimilation, resource transformation, and allometrically specified metabolic costs. Individual growth and reproduction requires a history of successful resource acquisition. Terrestrial producer, herbivore, and carnivore species classes are included, extensible to further classes. A grassland food chain model of “plants,” “grasshoppers,” and “spiders” is used to demonstrate ecosystem-level results of given individual-level behaviors. Ecosystem-level behaviors include a trophic cascade of indirect carnivore-producer interaction effects; stable persistence of all populations; a near-realistic biomass pyramid; and spatial competition and coexistence of multiple producer species. Initial Gecko results show promise for application in both theoretical and natural ecosystem modeling.

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Walters, Cory, and Richard Preston. "Net income risk, crop insurance and hedging." Agricultural Finance Review 78, no. 1 (2018): 135–51. http://dx.doi.org/10.1108/afr-05-2017-0036.

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Purpose At the beginning of the production year producers face a complex risk management decision environment given by risks specific to their operation, multiple crop insurance contracts and hedging opportunities. The purpose of this paper is to provide a producer-level framework for risk management decision making, focusing on the interaction between crop insurance and hedging. Design/methodology/approach The authors develop a Monte Carlo simulation model that generates a producer’s net income (NI) distribution that incorporates historical producer risk, price-yield correlation via a copula, price risk, and production costs. The authors evaluate the NI distribution through a modified Modern Portfolio Theory (MPT) decision framework. The authors use the modified MPT decision framework to explore tradeoffs between expected NI and farm ruin (defined as 1 or 5 percent expected shortfall) from different crop insurance contracts and pre-harvest hedging options. Findings Only revenue protection and the highest two levels of coverage level exist on the efficient frontier. The level of hedging on the efficient frontier ranges from 0 to 55 percent of Actual Production History. The authors find that increasing coverage level 5 percent (from 80 to 85 percent) negatively impacts the optimal hedging amount by 26 percentage points (from 35 to 9 percent). Originality/value The model provides the precise identification of financial benefits from different risk management strategies by incorporating producer-level historical yield data, using a copula to capture yield-price dependency structure and producer production cost in generating the NI distribution. This model can be applied to any producer’s characteristics and data.

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Dring, Colin, John F. Devlin, Gemma Boag, et al. "Incentives and disincentives identified by producers and drainage contractors/experts on the adoption of controlled tile drainage in eastern Ontario, Canada." Water Quality Research Journal 51, no. 1 (2015): 1–16. http://dx.doi.org/10.2166/wqrjc.2015.047.

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This study investigates incentives and disincentives regarding adoption of controlled tile drainage (CTD) in a region of eastern Ontario, Canada, where CTD could be used prolifically from a biophysical standpoint, but is not. Irrespective of documented environmental and agronomic benefits of CTD, adoption remains low. Surveys and semi-structured interviews with producers and drainage contractors/experts were used to evaluate awareness of CTD and identify producer adoption impediments. Surveys indicated nearly 70% of producer respondents had heard about CTD. Top ranked incentives identified by producers (who adopted) and drainage contractors/experts combined were: soil water retention benefits, increased crop yields, and gratification improving the environment. Top ranked disincentives combined by target groups were: increased farm labor, perceived lack of extension services, and costs. Many producer adopters emphasized motivators grounded in personal or community bearing, such as peer interaction and doing the right thing for the environment. Drainage contractors emphasized adoption impediments tied to a perceived lack of extension support for CTD. Drainage contractors themselves desired more extension support and firm data/research foundations with respect to advocating CTD to clients. With respect to motivation for producers to adopt CTD, this latter point may be critical given that producers highly valued drainage contractors as an information source on drainage practices.

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Ceballos, Yony Fernando, Jesus David Galarcio-Noguera, Pablo Andres Maya-Duque, and Gloria Lucia Ramirez-Cordoba. "Agent-based Model for Environmental Awareness and Extended Producer Responsibility in Developing Countries." Scientia et Technica 25, no. 3 (2020): 430–37. http://dx.doi.org/10.22517/23447214.24181.

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To make an effective transition towards a circular economy, we must have the responsibility and active participation of all the stakeholders involved, including customers. In this work, we seek to develop an agent-based model to describe and analyze an environmental awareness system in a population, whose behavior is based on an indicator that can change by agent’s interaction and modify its consumption habits. The model is described using the ODD + D protocol, and we use Netlogo software for coding. After model validation process, its results are analyzed to understand how can environmental awareness level, consumption habits and social skills of each individual influence on the average environmental awareness level of a heterogeneous population, which makes simple the identification of emerging behaviors and the forecasting of the potentially recyclable waste according to the quality in the separation at source.

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Batabyal, Amitrajeet A., and Hamid Beladi. "Advertising and Competition for Market Share between a New Good Producer and a Remanufacturer." German Economic Review 19, no. 1 (2018): 113–18. http://dx.doi.org/10.1111/geer.12121.

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Abstract We study the strategic interaction between a new good producer and a remanufacturer who use advertising campaigns to compete for a dominant share of the market for a certain good. Each firm chooses one of three possible strategies for running its advertising campaign. The two rival firms care only about capturing a dominant share of the relevant market. Hence, if a firm expects to capture dominant market share with probability p є [0, 1], then its payoff in the game we study is also p. Our analysis leads to four results. First, we provide the normal form representation of the game between the new good producer and the remanufacturer. Second, we specify the game in matrix form. Third, we indicate what happens at each stage of the elimination of strictly dominated strategies. Finally, we show that the iterated elimination of strictly dominated strategies yields a clear and unique prediction about the outcome of the advertising game.

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Laursen, Keld. "User–producer interaction as a driver of innovation: costs and advantages in an open innovation model." Science and Public Policy 38, no. 9 (2011): 713–23. http://dx.doi.org/10.3152/030234211x13070021633242.

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Munoz Arteaga, Jaime, Hector Cardona Reyes, Cesar A. Collazos Collazos Ordonez, and Juan Manuel Gonzalez-Calleros. "Producer–Consumer Model of a Textbook for the Community of Human–Computer Interaction in Latin America." IEEE Revista Iberoamericana de Tecnologias del Aprendizaje 11, no. 1 (2016): 23–30. http://dx.doi.org/10.1109/rita.2016.2518442.

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Kosonen, Miia, and Hanna-Kaisa Ellonen. "The Business Value of Consumer Participation through Social Media." International Journal of Interactive Communication Systems and Technologies 2, no. 1 (2012): 1–17. http://dx.doi.org/10.4018/ijicst.2012010101.

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Despite the growing enthusiasm about social media’s revolutionary potential, there is a lack of research on the possible business-side benefits. The authors maintain that in order to realize social media’s business potential, it is essential to identify the roles in which customers can participate in value co-creation. This study explores consumer participation enabled by social interaction technologies in the context of the newspaper and magazine industry. A qualitative analysis of 31 interviews with the publishers of the leading Finnish newspapers and magazines was conducted. A typology of six different roles of online consumer participation was developed: namely, agent, commentator, tester, debater, content producer, and messenger. The more company-driven types of participation (agent, commentator, and tester) can be integrated with product development support and learning from customers, the more consumer-driven types (debater, content producer, and messenger) are able to provide brand support and options for value co-creation.

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Lotz, Peter. "Demand as a Driving Force in Medical Innovation." International Journal of Technology Assessment in Health Care 9, no. 2 (1993): 174–88. http://dx.doi.org/10.1017/s0266462300004414.

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AbstractOn the basis of two case histories of medical device innovation, two aspects of demand are identified: (a) the prospect of new markets and (b) information about user needs. Conditions for direct interaction between the user and producer in the innovation process are identified. The article concludes with some normative implications for the publicly designed generation of new medical technology.

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Wu, Zhuoying, Chengsong Ye, Feng Guo, Shenghua Zhang, and Xin Yu. "Evidence for Broad-Spectrum Biofilm Inhibition by the Bacterium Bacillus sp. Strain SW9." Applied and Environmental Microbiology 79, no. 5 (2012): 1735–38. http://dx.doi.org/10.1128/aem.02796-12.

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ABSTRACTWe isolated aBacillussp. strain that could display broad-spectrum biofilm inhibition. The broad biofilm prevention could be achieved mainly by direct contact between inhibitor and target cells or was accompanied by an interaction with secreted inhibitory compounds. The repression of cell surface fimbria-like appendages of a biofilm producer was also observed; this was considered to contribute to the reduction in mixed biofilms.

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Liu, Deguang. "A Dynamic Evolutionary Game Model of Collaborative Innovation in Manufacturing Services Industry and Manufacturing Industry." International Journal of Circuits, Systems and Signal Processing 15 (August 26, 2021): 1099–108. http://dx.doi.org/10.46300/9106.2021.15.119.

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Collaborative innovation has a significant impact on the efficiency of manufacturing services and manufacturing innovation. In this paper, a collaborative innovation model of manufacturing services and manufacturing is constructed based on the two-dimensional asymmetric evolutionary game basic model. The stable evolution strategy of the model is to be found through the solutions to the replicator dynamic differential equation of both sides of the game. The results show that on the one hand, producer services can rely on the carrier of knowledge capital and human capital to link to the manufacturing process from front to back, and form the forward and backward spillover effect. On the other hand, the knowledge elements in producer services, especially tacit knowledge, are transmitted through the modern network under the common industrial culture atmosphere in the process of continuous industrial interaction and industrial integration, which can promote the sharing and transfer of knowledge, produce interactive innovation, and finally promote the innovation of value chain.

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Miranda, Rodrigo Otávio, Maria Emilene Martino Campos-Galvão, and Luís Augusto Nero. "Expression of genes associated with stress conditions by Listeria monocytogenes in interaction with nisin producer Lactococcus lactis." Food Research International 105 (March 2018): 897–904. http://dx.doi.org/10.1016/j.foodres.2017.12.030.

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Young, Won-Bin, Gary L. Lindberg, and Charles J. Link. "DNA Methylation of Helper Virus Increases Genetic Instability of Retroviral Vector Producer Cells." Journal of Virology 74, no. 7 (2000): 3177–87. http://dx.doi.org/10.1128/jvi.74.7.3177-3187.2000.

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ABSTRACT Retroviral vector producer cells (VPC) have been considered genetically stable. A clonal cell population exhibiting a uniform vector integration pattern is used for sustained vector production. Here, we observed that the vector copy number is increased and varied in a population of established LTKOSN.2 VPC. Among five subclones of LTKOSN.2 VPC, the vector copy number ranged from 1 to approximately 29 copies per cell. A vector superinfection experiment and Northern blot analysis demonstrated that suppression of helper virus gene expression decreased Env-receptor interference and allowed increased superinfection. The titer production was tightly associated with helper virus gene expression and varied between 0 and 2.2 × 105 CFU/ml in these subclones. In one analyzed subclone, the number of integrated vectors increased from one copy per cell to nine copies per cell during a 31-day period. Vector titer was reduced from 1.5 × 105 CFU to an undetectable level. To understand the mechanism involved, helper virus and vectors were examined for DNA methylation status by methylation-sensitive restriction enzyme digestion. We demonstrated that DNA methylation of helper virus 5′ long terminal repeat occurred in approximately 2% of the VPC population per day and correlated closely with inactivation of helper virus gene expression. In contrast, retroviral vectors did not exhibit significant methylation and maintained consistent transcription activity. Treatment with 5-azacytidine, a methylation inhibitor, partially reversed the helper virus DNA methylation and restored a portion of vector production. The preference for methylation of helper virus sequences over vector sequences may have important implications for host-virus interaction. Designing a helper virus to overcome cellular DNA methylation may therefore improve vector production. The maintenance of increased viral envelope-receptor interference might also prevent replication-competent retrovirus formation.

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Gonzaga, T. O. D., C. C. Vilar, A. S. Silva Filho, and V. L. Silva. "Bradyrhizobium and azospirllum interaction in soybean cultivars (Glycine Max (l.) Merrill) and their effects on productivity." Scientific Electronic Archives 13, no. 1 (2020): 60. http://dx.doi.org/10.36560/1312020864.

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Brazil is a major producer of soybeans and a model in the use of biological nitrogen fixation, however, few authors are investigating the use of more than one genus of bacteria acting alone and / or together. An example is the use of the diazotrophic bacteria of the genus Bradyrhizobium and Azospirillum, the latter besides the fixation presents growth promoting function. Thus, the objective of this bibliographic review and to verify the influence on the productive performance Bradyrhizobium japonicum and Azospirillum brasilense, in the soybean crop.

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Martínez, Carolina. "’This One’s for VIP Users!’: Participation and Commercial Strategies in Children’s Virtual Worlds." Culture Unbound 6, no. 3 (2014): 697–721. http://dx.doi.org/10.3384/cu.2000.1525.146697.

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Through the integrated framework of participation theory and political economy, this article analyzes participatory opportunities in the virtual world Habbo Hotel, and how participation is constrained and framed by the producer’s commercial strategies, which are based on advertising and sales of virtual goods. The study also looks into the ways in which the producer Sulake Corporation discursively represents the virtual world, and how the users with various forms of tactics try to bypass the commercial constraints. The methods used include observations of the English and Swedish language versions of Habbo Hotel, document analysis, and an interview with one designer employed by Sulake. The results show how participation in this virtual world takes minimalist forms, and that it is foremost an arena for interaction and consumption. Users’ participation in the virtual world is constrained by the commercial strategies in numerous ways, and the producer strategically takes advantage of children’s need to gain status in their peer group, in order to get them to purchase on the site. Habbo Hotel is represented by the producer as a safe and creative environment with learning opportunities for the children. Observations of the virtual world instead reveal Habbo as a panopticon-like shopping mall where users, through the practice of begging and other tactics, try to resist the commercial strategies. Virtual worlds could be potential spaces for children’s participation and contribute to a democratization of the social; however, this study shows how participation in this virtual world is clearly structured and limited for commercial purposes.

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Harirchi, Gouya, and Cristina Chaminade. "Exploring the Relation Between the Degree of Novelty of Innovations and User–Producer Interaction Across Different Income Regions." World Development 57 (May 2014): 19–31. http://dx.doi.org/10.1016/j.worlddev.2013.11.013.

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