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1

Goreglyad, V. "“Budget 3-Year Plan” (2006-2008) and the State Economic Policy." Voprosy Ekonomiki, no. 8 (August 20, 2005): 106–13. http://dx.doi.org/10.32609/0042-8736-2005-8-106-113.

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The article contains critical analysis of methodology of the medium-term budgetary forecasting in present-day Russia. This methodology is based on the monetarist principles understood in the way of vulgar economic theory. The author proposes a variant forecast of using budget proficit including the possibility of investment of its part. Special attention is paid to the problem of forming the effective state in Russia.
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Casu, Agostino. "« Translata proficit arbos » Le imprese “eteree” nelle Rime del Tasso." Italique, no. II (December 1, 1999): 81–111. http://dx.doi.org/10.4000/italique.200.

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Abalkin, L. "Thoughts on the Long-Term Strategy, Science and Democracy." Voprosy Ekonomiki, no. 12 (December 20, 2006): 4–19. http://dx.doi.org/10.32609/0042-8736-2006-12-4-19.

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The article covers unified issues of the long-term strategy development, the role of science as well as democracy development in present-day Russia. The problems of budget proficit, the Stabilization Fund issues, implementation of the adopted national projects, an increasing role of regions in strengthening the integrity and prosperity of the country are analyzed. The author reveals that the protection of businessmen and citizens from the all-embracing power of bureaucrats is the crucial condition of democratization of the society. Global trends of the world development and expert functions of
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4

Zaharia, Oana-Alis. "Translata Proficit: Revisiting John Florio’s translation of Michel de Montaigne’s Les Essais." Sederi, no. 22 (2012): 115–36. http://dx.doi.org/10.34136/sederi.2012.6.

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This paper considers John Florio’s famous translation of Montaigne’s Essays as a source of invaluable insight into the Elizabethan practice and theory of translation. In the letter addressed to the reader, Florio strongly advocates the use of translation as a means of advancing knowledge and developing the language and culture of a nation. Echoing the Elizabethan debate between the defenders and detractors of translation, his preface provides precious information on the various Elizabethan understandings of the role of translation. Casting himself in the role of a “foster-father”, Florio foreg
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Meszaros, Andrew. "‘Haec Traditio proficit’: Congar's Reception of Newman in Dei Verbum, Section 8." New Blackfriars 92, no. 1038 (2011): 247–54. http://dx.doi.org/10.1111/j.1741-2005.2010.01414.x.

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6

LaPorte, Justin L., Rupert J. Egan, Peter C. Hart, et al. "Qui non proficit, deficit: Experimental models for ‘integrative’ research of affective disorders." Journal of Affective Disorders 121, no. 1-2 (2010): 1–9. http://dx.doi.org/10.1016/j.jad.2009.04.010.

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Desan, Philippe. "« Translata proficit » : John Florio, sa réécriture des Essais et l’influence de la langue de Montaigne-Florio sur Shakespeare." Actes des congrès de la Société française Shakespeare, no. 21 (November 1, 2004): 29–93. http://dx.doi.org/10.4000/shakespeare.151.

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Pavlovskyi, V. V., and A. V. Prykhodko. "APPLICATION OF HVDC SYSTEMS FOR RES INTEGRATION AND POWER TRANSMISSION FROM THE PROFICIT SOUTH PART OF THE IES OF UKRAINE." Praci Institutu elektrodinamiki Nacionalanoi akademii nauk Ukraini 2021, no. 59 (2021): 36–42. http://dx.doi.org/10.15407/publishing2021.59.036.

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The analysis and estimation of advantages from implementation of HVDC systems in parallel to the loaded alternating current lines as a means of solving the problem of power output from surplus energy regions of the IES of Ukraine was presented. Such regions arise with the active development of new Renewable Energy Resources (RES). Two variants of installation of such systems are proposed and the corresponding analysis of electrical modes of IES of Ukraine with reliability criteria "N-1" was executed. References 11, figures 4, table 1.
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Lasauskas, Eduardas, and Laurynas Naujokaiti. "ANALYSIS OF THREE WING SECTIONS." Aviation 13, no. 1 (2009): 3–10. http://dx.doi.org/10.3846/1648-7788.2009.13.3-10.

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Three wing sections FX66-S-196VI, E603 and AH82–150A were analyzed. Measured data of these wing sections are published. First wing section was measured in Stuttgart University and in Delft University of Technology, when other two wing sections were measured in Stuttgart University. These wing sections have different behavior in the region of maximum lift. FX66‐S‐196VI wing section has sharp drop in lift. The stall of the second and third wing sections is smooth, though different. All wing sections are affected by laminar separation bubbles. The calculations were performed using three codes: Ep
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Ginevičienė, Valentina, and Gabrielius Buzas. "BENDRO GENOTIPŲ ĮVERČIO ANALIZĖ VERTINANT POLIGENINĮ SPORTO PROFILĮ LIETUVOS FUTBOLININKŲ POPULIACIJOJE." Health Sciences 35, no. 1 (2025): 66–71. https://doi.org/10.35988/sm-hs.2025.011.

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Bendras genotipų įvertis (BGĮ) yra vis plačiau naudo­jamas analizuojant suminį poligeninį sportinių savybių profilį. Tyrimo tikslas − išanalizuoti ir įvertinti Lietuvos profesionalių futbolininkų ir nesportuojančių vyrų fizinio pajėgumo ir traumų rizikos poligeninio profilio ypatu­mus. Tyrimo metu buvo siekiama išsiaiškinti potencialias sąsajas tarp BGĮ ir sportininko statuso, futbolininko pa­dėties aikštelėje ir traumų rizikos. Tyrimo metu buvo su­darytas aerobinio/anaerobinio pajėgumo ir traumų rizikos BGĮ 150 vyriškos lyties Lietuvos futbolo žaidėjų ir 150 profesionaliai nesportuojančių vyr
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Dringelytė, Kristina, and Jurgita Gulbinienė. "SLAUGYTOJŲ MIEGO IR GYVENIMO KOKYBĖS SĄSAJOS." Health Sciences 29, no. 6 (2019): 195–200. http://dx.doi.org/10.35988/sm-hs.2019.126.

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Tyrimo tikslas – ištirti slaugytojų miego kokybės ryšį su gyvenimo kokybe. Tyrimo metodika. Atliktas kiekybinis tyrimas – anoniminė anketinė apklausa raštu. Apklaustos Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų chirurgijos, terapijos ir intensyvios terapijos (IT) skyriuose dirbančios slaugytojos. Tyrimui naudotas Pitsburgo miego kokybės indeksas (PMKI), gyvenimo kokybės klausimynas „SF-36“ ir papildomai sudaryti klausimai. Tyrimo rezultatai. Skirtingo profilio skyrių slaugytojai patiria miego sutrikimus, nes visų tiriamųjų bendrojo PMKI vidurkis didesnis kaip 5 balai. Inten
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Kim, Sung Hui. "The Profit Principle: Tracing the Moral Decline of Corporate Law Firms." Michigan Law Review, no. 122.6 (2024): 1321. http://dx.doi.org/10.36644/mlr.122.6.profit.

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Žuraulis, Vidas. "IMPACT OF THE ROAD PROFILE ON VEHICLE DECELERATION / IŠILGINIO KELIO PROFILIO ĮTAKA AUTOMOBILIO LĖTĖJIMO PAGREIČIUI." Mokslas - Lietuvos ateitis 4, no. 4 (2012): 403–7. http://dx.doi.org/10.3846/mla.2012.65.

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The article analyzes the impact of the longitudinal road profile on the efficiency of car braking estimated applying deceleration value. Different formulas are used for theoretical calculations, and therefore experimental brakes in different road slopes were performed to obtain the most accurate results. Deceleration, as one of the most important safety parameters, depends on the technical condition of the braking system, road conditions and structural and dynamic properties of the other car. Road alignments can significantly affect car manageability, because of weight transfer and extra track
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Lillehoj, Hyun, Sung Hyen Lee, Laurent Dupuis, and Juliette Ben Arous. "Evaluation of Montanide™ ISA 71 VG adjuvant against coccidiosis (VET2P.1030)." Journal of Immunology 192, no. 1_Supplement (2014): 207.2. http://dx.doi.org/10.4049/jimmunol.192.supp.207.2.

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Abstract Chickens were immunized subcutaneously with an Eimeria recombinant profilin protein plus MontanideTM ISA 70 VG (ISA70) or MontanideTM ISA 71 VG (ISA 71) water-in-oil adjuvants, or with profilin alone. While immunization with profilin/ISA 70 vs. profilin alone altered the levels of more total transcripts compared with profilin/ISA 71 vs. profilin alone (509 vs. 296), the latter was associated with a greater number of unique biological functions, and a larger number of genes within these functions, compared with the former. Canonical pathway analysis identified 10 pathways related with
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15

Bezhanishvili, Guram, and Patrick J. Morandi. "Profinite Heyting Algebras and Profinite Completions of Heyting Algebras." gmj 16, no. 1 (2009): 29–47. http://dx.doi.org/10.1515/gmj.2009.29.

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Abstract This paper surveys recent developments in the theory of profinite Heyting algebras (resp. bounded distributive lattices, Boolean algebras) and profinite completions of Heyting algebras (resp. bounded distributive lattices, Boolean algebras). The new contributions include a necessary and sufficient condition for a profinite Heyting algebra (resp. bounded distributive lattice) to be isomorphic to the profinite completion of a Heyting algebra (resp. bounded distributive lattice). This results in simple examples of profinite bounded distributive lattices that are not isomorphic to the pro
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Di Nardo, A., R. Gareus, D. Kwiatkowski, and W. Witke. "Alternative splicing of the mouse profilin II gene generates functionally different profilin isoforms." Journal of Cell Science 113, no. 21 (2000): 3795–803. http://dx.doi.org/10.1242/jcs.113.21.3795.

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Profilins are a conserved family of proteins participating in actin dynamics and cell motility. In the mouse, two profilin genes are known. Profilin I is expressed universally at high levels, while profilin II is expressed mainly in the brain. Here we describe the occurrence of two mouse profilin II isoforms, A and B, which are derived by alternative splicing. They are identical through residue 107 of the protein, but then have distinct C-terminal sequences. Profilin IIA binds to poly-L-proline and actin with high affinity similar to profilin I. Profilin IIB on the other hand does not bind to
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Di Domenico, Marina, Melanie Jokwitz, Walter Witke, and Pietro Pilo Boyl. "Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure." Cells 10, no. 9 (2021): 2310. http://dx.doi.org/10.3390/cells10092310.

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Profilin functions have been discussed in numerous cellular processes, including actin polymerization. One puzzling aspect is the concomitant expression of more than one profilin isoform in most tissues. In neuronal precursors and in neurons, profilin 1 and profilin 2 are co-expressed, but their specific and redundant functions in brain morphogenesis are still unclear. Using a conditional knockout mouse model to inactivate both profilins in the developing CNS, we found that threshold levels of profilin are necessary for the maintenance of the neuronal stem-cell compartment and the generation o
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18

Haugwitz, M., A. A. Noegel, D. Rieger, F. Lottspeich, and M. Schleicher. "Dictyostelium discoideum contains two profilin isoforms that differ in structure and function." Journal of Cell Science 100, no. 3 (1991): 481–89. http://dx.doi.org/10.1242/jcs.100.3.481.

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Two profilin isoforms (profilins I and II) have been purified from Dictyostelium discoideum, using affinity chromatography on a poly(L-proline) matrix; the isoforms could be separated by cation-exchange chromatography on a FPLC system. The gene coding for profilin I was cloned from a lambda gt11 cDNA library using a profilin I-specific monoclonal antibody. The profilin II cDNA was isolated by probing the cDNA library with an oligonucleotide deduced from the N-terminal amino acid sequence of profilin II, which has an open N terminus in contrast to profilin I. The deduced amino acid sequences of
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 . "Dutch Cochrane Centre proficiat!" Huisarts en Wetenschap 50, no. 4 (2007): 227. http://dx.doi.org/10.1007/bf03085120.

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Kletzien, Sharon Benge. "Proficient and Less Proficient Comprehenders' Strategy use for Different Top-Level Structures." Journal of Reading Behavior 24, no. 2 (1992): 191–215. http://dx.doi.org/10.1080/10862969209547772.

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This study examined proficient and less proficient high school comprehenders' use of strategies as they read three passages with different top-level structures: collection, causation, and comparison. Subjects were 24 tenth and eleventh graders who were divided into proficient and less proficient comprehenders based on results of standardized comprehension tests: proficient comprehenders scored above the 70th percentile; less proficient comprehenders below the 50th percentile. Content area passages were used with the proficient comprehenders and were revised for the less proficient comprehender
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RHODES, JOHN, and BENJAMIN STEINBERG. "PROFINITE SEMIGROUPS, VARIETIES, EXPANSIONS AND THE STRUCTURE OF RELATIVELY FREE PROFINITE SEMIGROUPS." International Journal of Algebra and Computation 11, no. 06 (2001): 627–72. http://dx.doi.org/10.1142/s0218196701000784.

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Building on the now generally accepted thesis that profinite semigroups are important to the study of finite semigroups, this paper proposes to apply various of the techniques, already used in studying algebraic semigroups, to profinite semigroups. The goal in mind is to understand free profinite semigroups on a finite set. To do this we define profinite varieties. We then introduce expansions of profinite semigroups, giving examples of several classes of such expansions. These expansions will then be useful in studying various structural properties of relatively free profinite semigroups, sin
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Koll-Schretzenmayr, Martina. "Profit! Profit?" disP - The Planning Review 51, no. 2 (2015): 2–3. http://dx.doi.org/10.1080/02513625.2015.1064606.

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23

Kaiser, D. A., V. K. Vinson, D. B. Murphy, and T. D. Pollard. "Profilin is predominantly associated with monomeric actin in Acanthamoeba." Journal of Cell Science 112, no. 21 (1999): 3779–90. http://dx.doi.org/10.1242/jcs.112.21.3779.

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We used biochemical fractionation, immunoassays and microscopy of live and fixed Acanthamoeba to determine how much profilin is bound to its known ligands: actin, membrane PIP(2), Arp2/3 complex and polyproline sequences. Virtually all profilin is soluble after gentle homogenization of cells. During gel filtration of extracts on Sephadex G75, approximately 60% of profilin chromatographs with monomeric actin, 40% is free and none voids with Arp2/3 complex or other large particles. Selective monoclonal antibodies confirm that most of the profilin is bound to actin: 65% in extract immunoadsorptio
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Lu, Jia, and Thomas D. Pollard. "Profilin Binding to Poly-l-Proline and Actin Monomers along with Ability to Catalyze Actin Nucleotide Exchange Is Required for Viability of Fission Yeast." Molecular Biology of the Cell 12, no. 4 (2001): 1161–75. http://dx.doi.org/10.1091/mbc.12.4.1161.

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We tested the ability of 87 profilin point mutations to complement temperature-sensitive and null mutations of the single profilin gene of the fission yeast Schizosaccharomyces pombe. We compared the biochemical properties of 13 stable noncomplementing profilins with an equal number of complementing profilin mutants. A large quantitative database revealed the following: 1) in a profilin null background fission yeast grow normally with profilin mutations having >10% of wild-type affinity for actin or poly-l-proline, but lower affinity for either ligand is incompatible with life; 2) in thecdc
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Raed, Latif Ugla, Jafre Zainol Abidin Mohamad, and Najim Abdullah Mohammed. "The influence of proficiency level on the use and choice of L1/L2 communication strategies used by Iraqi EFL students." International Journal of Evaluation and Research in Education (IJERE) 8, no. 1 (2019): 127–37. https://doi.org/10.11591/ijere.v8i1.15179.

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This study aimed to investigate the influence of language proficiency level on the frequency of the use and choice of L1/L2 communication strategies used by Iraqi EFL students. This study was qualitative in nature. The interactive task and speaking task were used to gather data regarding communication strategy use and choice from<em> </em>52 second and third year English major students. Those participants were divided into two groups; low and high proficient students (n=27 low proficient students and n=25 high proficient students). Taxonomy of communication strategies was adopted to code the c
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Vandekerckhove, J. S., D. A. Kaiser, and T. D. Pollard. "Acanthamoeba actin and profilin can be cross-linked between glutamic acid 364 of actin and lysine 115 of profilin." Journal of Cell Biology 109, no. 2 (1989): 619–26. http://dx.doi.org/10.1083/jcb.109.2.619.

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Acanthamoeba profilin was cross-linked to actin via a zero-length isopeptide bond using carbodiimide. The covalently linked 1:1 complex was purified and treated with cyanogen bromide. This cleaves actin into small cyanogen bromide (CNBr) peptides and leaves the profilin intact owing to its lack of methionine. Profilin with one covalently attached actin CNBr peptide was purified by gel filtration followed by gel electrophoresis and electroblotting on polybase-coated glass-fiber membranes. Since the NH2 terminus of profilin is blocked, Edman degradation gave only the sequence of the conjugated a
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Wolven, Amy K., Lisa D. Belmont, Nicole M. Mahoney, Steven C. Almo, and David G. Drubin. "In Vivo Importance of Actin Nucleotide Exchange Catalyzed by Profilin." Journal of Cell Biology 150, no. 4 (2000): 895–904. http://dx.doi.org/10.1083/jcb.150.4.895.

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The actin monomer-binding protein, profilin, influences the dynamics of actin filaments in vitro by suppressing nucleation, enhancing nucleotide exchange on actin, and promoting barbed-end assembly. Profilin may also link signaling pathways to actin cytoskeleton organization by binding to the phosphoinositide PIP2 and to polyproline stretches on several proteins. Although activities of profilin have been studied extensively in vitro, the significance of each of these activities in vivo needs to be tested. To study profilin function, we extensively mutagenized the Saccharomyces cerevisiae profi
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TAMURA, MASAHITO, NOBUYUKI YANAGIHARA, HIROSHI TANAKA, et al. "Activation of DNA Synthesis and AP-1 by Profilin, an Actin-Binding Protein, via Binding to a Cell Surface Receptor in Cultured Rat Mesangial Cells." Journal of the American Society of Nephrology 11, no. 9 (2000): 1620–30. http://dx.doi.org/10.1681/asn.v1191620.

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Abstract.Profilin is known to bind to actin monomers (to regulate actin polymerization) and to phosphatidylinositol-4,5-bisphosphate (to inhibit hydrolysis by unphosphorylated phospholipase C-γl). It was recently reported that profilin is overexpressed in glomerular mesangial cells (MC) of rats with anti-Thy-1.1-induced glomerulonephritis and is accumulated in the extracellular space around MC. In this study, the biologic activities of extracellular profilin were examined. Scatchard analysis indicated the existence of a single class of cell surface binding sites, with similar equilibrium disso
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Tang, Dale D., and Jian Tan. "Downregulation of profilin with antisense oligodeoxynucleotides inhibits force development during stimulation of smooth muscle." American Journal of Physiology-Heart and Circulatory Physiology 285, no. 4 (2003): H1528—H1536. http://dx.doi.org/10.1152/ajpheart.00188.2003.

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The actin-regulatory protein profilin has been shown to regulate the actin cytoskeleton and the motility of nonmuscle cells. To test the hypothesis that profilin plays a role in regulating smooth muscle contraction, profilin antisense or sense oligodeoxynucleotides were introduced into the canine carotid smooth muscle by a method of reversible permeabilization, and these strips were incubated for 2 days for protein downregulation. The treatment of smooth muscle strips with profilin antisense oligodeoxynucleotides inhibited the expression of profilin; it did not influence the expression of acti
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Thawarom, Thiwaporn, Jeffrey D. Wilang, and Wareesiri Singhasiri. "Metacognitive Knowledge in Performing a Speaking Task: A Report From High and Low Proficient Thai University Students." Journal of Language Teaching and Research 13, no. 3 (2022): 609–19. http://dx.doi.org/10.17507/jltr.1303.17.

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This study analyzes the use of metacognitive knowledge in performing a speaking task between high-proficient and low-proficient university students. The data was collected by employing stimulated recall interviews from 34-first year students. The data was coded deductively by using metacognitive knowledge frameworks. The results showed that the students employed all types of metacognitive knowledge in their speaking. Both high-proficient and low-proficient students prominently manifested strategy knowledge such as vocabulary strategies, planning strategies and problem-solving strategies. Howev
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J. Tolibas, Mae Caroline. "MATHEMATICS PROFICIENCY OF LEARNERS IN GRADES 1 TO 3: INSIGHTS FROM THE RAPID MATHEMATICS ASSESSMENT (RMA) OUTCOMES." International Journal of Education Humanities and Social Science 08, no. 01 (2025): 24–32. https://doi.org/10.54922/ijehss.2025.0886.

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Mathematical proficiency in early grades is critical for foundational learning. This study assessed the mathematical proficiency of learners in Grades 1 to 3 at a public elementary school in the DepEd Tacloban City Division using Rapid Mathematics Assessment (RMA) outcomes. Using a descriptive survey design, data were gathered from 222 students through the RMA, categorizing learners into five proficiency levels: Highly Proficient, Proficient, Nearly Proficient, Low Proficient, and Non-Proficient. Results revealed that most students were in the Emerging (Low Proficient and Non-Proficient) categ
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Southwick, F. S., and C. L. Young. "The actin released from profilin--actin complexes is insufficient to account for the increase in F-actin in chemoattractant-stimulated polymorphonuclear leukocytes." Journal of Cell Biology 110, no. 6 (1990): 1965–73. http://dx.doi.org/10.1083/jcb.110.6.1965.

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Chemoattractant stimulation of polymorphonuclear leukocytes is associated with a nearly two-fold rise in actin filament content. We examined the role of the actin monomer sequestering protein, profilin, in the regulation of PMN actin filament assembly during chemoattractant stimulation using a Triton extraction method. Poly-L-proline-conjugated Sepharose beads were used to assess the relative concentration of actin bound to profilin with high enough affinity to withstand dilution (profilin-actin complex) and DNase I-conjugated beads to measure the relative concentration of actin in the Triton-
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Ardila, Istiqamah. "Writing Strategies Used by Indonesian EFL Undergraduate Students across Their Proficiency and Gender." Journal of Language Intelligence and Culture 1, no. 02 (2020): 138–49. http://dx.doi.org/10.35719/jlic.v1i02.20.

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Proficient writers in L2 setting used many kinds of strategies to face their difficulties in English writing. This study investigates the writing strategies used by Indonesian EFL undergraduate students and examines if there is any differences between proficient and less proficient students across their gender in choosing strategies in writing. The subject of the study consisted of 100 (one hundred) undergraduate students of English Department in Islamic State University of Antasari, Banjarmasin. A questionnaire was adopted from Peñuelas (2012) to gather data about student writing strategies.
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TAMURA, MASAHITO, HIROSHI TANAKA, AKIRA YASHIRO, et al. "Expression of Profilin, an Actin-Binding Protein, in Rat Experimental Glomerulonephritis and Its Upregulation by Basic Fibroblast Growth Factor in Cultured Rat Mesangial Cells." Journal of the American Society of Nephrology 11, no. 3 (2000): 423–33. http://dx.doi.org/10.1681/asn.v113423.

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Abstract. Profilin binds to actin monomer to regulate actin polymerization, and to phosphatidylinositol 4,5-biphosphate to inhibit hydrolysis by phospholipase Cγ1. This study investigated the expression of profilin in rat anti-Thy-1.1 mesangial proliferative glomerulonephritis (GN) and examined the effect of growth factors on its expression in cultured rat mesangial cells. Profilin mRNA was constitutively expressed in isolated glomeruli of untreated rats. However, in glomeruli of anti-Thy-1.1 GN rats, its expression was upregulated beginning on day 1, reaching a peak level on day 4 (3.9-fold v
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Ardila, Istiqamah. "Writing Strategies Used by Indonesian EFL Undergraduate Students across Their Proficiency and Gender." Journal of Language Intelligence and Culture 2, no. 1 (2020): 16–27. http://dx.doi.org/10.35719/jlic.v2i1.20.

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Proficient writers in L2 setting used many kinds of strategies to face their difficulties in English writing. This study investigates the writing strategies used by Indonesian EFL undergraduate students and examines if there is any differences between proficient and less proficient students across their gender in choosing strategies in writing. The subject of the study consisted of 100 (one hundred) undergraduate students of English Department in Islamic State University of Antasari, Banjarmasin. A questionnaire was adopted from Peñuelas (2012) to gather data about student writing strategies.
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Salvador, Juvelyn. "Attitudes and Language Proficiency of College Students at Catanduanes State University Panganiban Campus." JPAIR Institutional Research 19, no. 1 (2022): 68–86. http://dx.doi.org/10.7719/irj.v19i1.837.

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The study determined the attitudes toward the English language, the general proficiency level of 60 selected first-year college students, language structure, reading comprehension, and vocabulary. This was conducted to solve current issues of reading comprehension difficulties and poor linguistic competence in English subjects. It utilized descriptive research. Findings revealed “zero highly unfavorable” attitudes towards English; 2 “highly favorable.” For language structure, half of them were “slightly proficient,” 26 (43.33%) “Proficient,” 2 (3.33%) “Moderately proficient,” and 2 (3.33%) “Ve
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Uemura, Wataru, and Shoji Tatsumi. "About the Reinforcement Function for Profit Sharing." Transactions of the Japanese Society for Artificial Intelligence 19 (2004): 197–203. http://dx.doi.org/10.1527/tjsai.19.197.

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38

Saito, Ken, and Shiro Masuda. "Profit Sharing Introducing the Judgement of Incomplete Perception." Transactions of the Japanese Society for Artificial Intelligence 19 (2004): 379–88. http://dx.doi.org/10.1527/tjsai.19.379.

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39

Ugla, Raed Latif, Mohamad Jafre Zainol Abidin, and Mohammed Najim Abdullah. "The influence of proficiency level on the use and choice of L1/L2 communication strategies used by Iraqi EFL students." International Journal of Evaluation and Research in Education (IJERE) 8, no. 1 (2019): 127. http://dx.doi.org/10.11591/ijere.v8i1.15179.

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&lt;span&gt;This study aimed at investigating the influence of language proficiency level on the frequency of the use and choice of L1/L2 communication strategies used by Iraqi EFL students. This study was qualitative in nature. The interactive task and speaking task were used to gather data regarding communication strategy use and choice from&lt;em&gt; &lt;/em&gt;52 second and third year English major students. Those participants were divided into two groups; low and high proficient students (n=27 low proficient students and n=25 high proficient students). A taxonomy of communication strategi
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40

Goldschmidt-Clermont, P. J., L. M. Machesky, S. K. Doberstein, and T. D. Pollard. "Mechanism of the interaction of human platelet profilin with actin." Journal of Cell Biology 113, no. 5 (1991): 1081–89. http://dx.doi.org/10.1083/jcb.113.5.1081.

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We have reexamined the interaction of purified platelet profilin with actin and present evidence that simple sequestration of actin monomers in a 1:1 complex with profilin cannot explain many of the effects of profilin on actin assembly. Three different methods to assess binding of profilin to actin show that the complex with platelet actin has a dissociation constant in the range of 1 to 5 microM. The value for muscle actin is similar. When bound to actin, profilin increases the rate constant for dissociation of ATP from actin by 1,000-fold and also increases the rate of dissociation of Ca2+
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41

Yang, Changsong, Minzhou Huang, John DeBiasio, et al. "Profilin Enhances Cdc42-Induced Nucleation of Actin Polymerization." Journal of Cell Biology 150, no. 5 (2000): 1001–12. http://dx.doi.org/10.1083/jcb.150.5.1001.

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We find that profilin contributes in several ways to Cdc42-induced nucleation of actin filaments in high speed supernatant of lysed neutrophils. Depletion of profilin inhibited Cdc42-induced nucleation; re-addition of profilin restored much of the activity. Mutant profilins with a decreased affinity for either actin or poly-l-proline were less effective at restoring activity. Whereas Cdc42 must activate Wiskott-Aldrich Syndrome protein (WASP) to stimulate nucleation by the Arp2/3 complex, VCA (verpolin homology, cofilin, and acidic domain contained in the COOH-terminal fragment of N-WASP) cons
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42

Lambrechts, Anja, Attila Braun, Veronique Jonckheere, et al. "Profilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties." Molecular and Cellular Biology 20, no. 21 (2000): 8209–19. http://dx.doi.org/10.1128/mcb.20.21.8209-8219.2000.

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ABSTRACT We deduced the structure of the mouse profilin II gene. It contains five exons that can generate four different transcripts by alternative splicing. Two transcripts encode different profilin II isoforms (designated IIa and IIb) that have similar affinities for actin but different affinities for polyphosphoinositides and proline-rich sequences. Profilins IIa and IIb are also present in humans, suggesting that all mammals have three profilin isoforms. Profilin I is the major form in all tissues, except in the brain, where profilin IIa is most abundant. Profilin IIb appears to be a minor
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43

Schluter, K., M. Schleicher, and B. M. Jockusch. "Effects of single amino acid substitutions in the actin-binding site on the biological activity of bovine profilin I." Journal of Cell Science 111, no. 22 (1998): 3261–73. http://dx.doi.org/10.1242/jcs.111.22.3261.

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For a detailed analysis of the profilin-actin interaction, we designed several point mutations in bovine profilin I by computer modeling. The recombinant proteins were analyzed in vitro for their actin-binding properties. Mutant proteins with a putatively higher affinity for actin were produced by attempting to introduce an additional bond to actin. However, these mutants displayed a lower affinity for actin than wild-type profilin, suggesting that additional putative bonds created this way cannot increase profilin's affinity for actin. In contrast, mutants designed to have a reduced affinity
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44

Hartwig, J. H., K. A. Chambers, K. L. Hopcia, and D. J. Kwiatkowski. "Association of profilin with filament-free regions of human leukocyte and platelet membranes and reversible membrane binding during platelet activation." Journal of Cell Biology 109, no. 4 (1989): 1571–79. http://dx.doi.org/10.1083/jcb.109.4.1571.

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Profilin is a conserved, widely distributed actin monomer binding protein found in eukaryotic cells. Mammalian profilin reversibly sequesters actin monomers in a high affinity profilactin complex. In vitro, the complex is dissociated in response to treatment with the polyphosphoinositides, phosphatidylinositol monophosphate, and phosphatidylinositol 4,5-bisphosphate. Here, we demonstrate the ultrastructural immunolocalization of profilin in human leukocytes and platelets. In both cell types, a significant fraction of profilin is found associated with regions of cell membrane devoid of actin fi
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45

Machesky, L. M., P. J. Goldschmidt-Clermont, and T. D. Pollard. "The affinities of human platelet and Acanthamoeba profilin isoforms for polyphosphoinositides account for their relative abilities to inhibit phospholipase C." Cell Regulation 1, no. 12 (1990): 937–50. http://dx.doi.org/10.1091/mbc.1.12.937.

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In light of recent work implicating profilin from human platelets as a possible regulator of both cytoskeletal dynamics and inositol phospholipid-mediated signaling, we have further characterized the interaction of platelet profilin and the two isoforms of Acanthamoeba profilin with inositol phospholipids. Profilin from human platelets binds to phosphatidylinositol-4-monophosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2) with relatively high affinity (Kd approximately 1 microM for PIP2 by equilibrium gel filtration), but interacts only weakly (if at all) with phosphatidylinositol
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46

ALKİBAY, Turgut, Serhat GÜROCAK, İyimser ÜRE, et al. "Profile of Prostatectomy Cases." Turkiye Klinikleri Journal of Medical Sciences 34, no. 1 (2014): 53–59. http://dx.doi.org/10.5336/medsci.2013-35571.

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47

Liu, Jun, Qiao-Chu Wang, Xing Duan, et al. "Profilin 1 plays feedback role in actin-mediated polar body extrusion in mouse oocytes." Reproduction, Fertility and Development 30, no. 5 (2018): 752. http://dx.doi.org/10.1071/rd17354.

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Mammalian oocytes undergo several crucial processes during meiosis maturation, including spindle formation and migration and polar body extrusion, which rely on the regulation of actin. As a small actin-binding protein, profilin 1 plays a central role in the regulation of actin assembly. However, the functions of profilin 1 in mammalian oocytes are uncertain. To investigate the function of profilin 1 in oocytes, immunofluorescent staining was first used to examine profilin 1 localisation. The results showed that profilin 1 was localised around the meiotic spindles and was colocalised with cyto
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48

Güçlü, Aydın, Kağan Tur, Ömer Jaradat, et al. "Profilin as a Novel Biomarker for Assessing Atherosclerosis in Hemodialysis Patients." Kardiologiia 65, no. 5 (2025): 16–20. https://doi.org/10.18087/cardio.2025.5.n2605.

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Aim. Studies have shown a significant correlation between atherosclerosis and profilin-1. However, there is no information in the literature on the concentration of profilin in hemodialysis (HD) patients. This research examined the association between profilin-1 and carotid intima-media thickness (CIMT), as a marker of early atherosclerosis in HD patients.Material and methods. 50 chronic HD patients and 38 healthy, control patients were included in this study. CIMT was measured by high-resolution ultrasonography.Results. The HD patients were older and had higher concentrations of profilin-1, C
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49

Milošević, Srđan. "IMPLEMENTACIJA PROFINET PROTOKOLA ZA INDUSTRIJSKE UREĐAJE." Zbornik radova Fakulteta tehničkih nauka u Novom Sadu 38, no. 08 (2023): 1041–44. http://dx.doi.org/10.24867/23ih01milosevic.

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U radu je prikazan postupak razvoja PROFINET protokola na Hardware In the Loop (HIL) uređajima. Date su karakteristike i specifičnosti PROFINET protokola. Opisana je realizacija aplikacije i grafičkog interfejsa za PROFINET, način konfigurisanja uređaja u TIA Portal-u kao i način uspostavljanja komunikacije između uređaja. Ispitana je ispravnost implementiranog protokola u Tajfun HIL programskom okruženju i dati su rezultati testiranja PROFINET protokola.
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50

Shao, Jieya, William J. Welch, Nicholas A. DiProspero, and Marc I. Diamond. "Phosphorylation of Profilin by ROCK1 Regulates Polyglutamine Aggregation." Molecular and Cellular Biology 28, no. 17 (2008): 5196–208. http://dx.doi.org/10.1128/mcb.00079-08.

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ABSTRACT Y-27632, an inhibitor of the Rho-associated kinase ROCK, is a therapeutic lead for Huntington disease (HD). The downstream targets that mediate its inhibitory effects on huntingtin (Htt) aggregation and toxicity are unknown. We have identified profilin, a small actin-binding factor that also interacts with Htt, as being a direct target of the ROCK1 isoform. The overexpression of profilin reduces the aggregation of polyglutamine-expanded Htt and androgen receptor (AR) peptides. This requires profilin's G-actin binding activity and its direct interaction with Htt, which are both inhibit
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