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Journal articles on the topic 'Proflavine'

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Published: 4 June 2021
Last updated: 9 February 2022

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1

&NA;. "Proflavine." Reactions Weekly &NA;, no. 374 (October 1991): 6–7. http://dx.doi.org/10.2165/00128415-199103740-00033.

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2

Girousi, S., and V. Kinigopoulou. "Detection of short oligonucleotide sequences using an electrochemical DNA hybridization biosensor." Open Chemistry 8, no. 4 (August 1, 2010): 732–36. http://dx.doi.org/10.2478/s11532-010-0056-5.

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AbstractAn electrochemical DNA hybridization biosensor was developed for the detection of DNA hybridization using MDB and proflavine as electrochemical labels. The biosensor was based on the interaction of 7-dimethyl-amino-1,2-benzophenoxazi-nium Meldola’s Blue (MDB) and proflavine with double stranded DNA (dsDNA) The electrochemical behaviour of MDB and proflavine as well as its interaction with double stranded (dsDNA) were investigated by cyclic (CV) and square wave voltammetry (SWV) and screen printed electrodes (ScPE). Furthermore, DNA-hybridization biosensors were developed for the detection of hybridization between oligonucleotides, which was detected by studying changes in the voltammetric peaks of MDB (reduction peak at −0.251 V) and proflavine (reduction peak at 0.075 V). MDB and proflavine were found to intercalate between the base pairs of dsDNA and oligonucleotides. Several factors affecting the dsDNA or oligonucleotides immobilization, hybridization and indicator preconcentration and interaction time, were investigated. As a result of the interaction of MDB with dsDNA and hybridized oligonucleotides, the voltammetric signals of MDB increased. Furthermore, guanine’s oxidation peak (at 0.901 V) was decreased as MDB’s concentration was increased. As a result of the interaction of proflavine with dsDNA and hybridized oligonucleotides, the voltammetric signals of proflavine decreased. These results were similar for carbon paste and screen printed electrodes. A comparison of the performance between CPE and ScPE was done. Our results showed that lower concentrations of MDB and proflavine were detected using screen printed electrodes. Moreover, reproducibility was better using screen printed electrodes and the detection was faster (regarding the experimental steps), but they are more cost effective.
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3

Cisárikováa, Alžbeta, Pavel Abaffy, Ján Imrich, and Helena Paulíková. "Photocleavage of pDNA by bis-imidazolidino and bis-thioureido proflavines." Acta Chimica Slovaca 8, no. 2 (October 1, 2015): 97–100. http://dx.doi.org/10.1515/acs-2015-0017.

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Abstract New photosensitizers are needed for photodynamic antimicrobial and anticancer chemotherapy. Two new groups of proflavine derivatives have been recently prepared and their action on the cancer cells has been investigated by our research team. In this paper, we studied an effect of UV-A irradiation of two groups of proflavines: 3,6-bis((1-alkyl-5-oxo-imidazolidin-2-yliden)imino)acridine hydrochlorides (AcrDIMs) and 1’,1”-(acridin-3,6-diyl)-3’,3”-dialkyldithiourea hydrochlorides (AcrDTUs) on a plasmid DNA (pDNA). These compounds induced a photocleavage of pDNA characteristic by generation of free radicals, single strand DNA breaks and formation of an open circular form of pDNA.
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4

Streisinger, George, and Joyce Emrich Owen. "MECHANISMS OF SPONTANEOUS AND INDUCED FRAMESHIFT MUTATION IN BACTERIOPHAGE T4." Genetics 109, no. 4 (April 1, 1985): 633–59. http://dx.doi.org/10.1093/genetics/109.4.633.

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ABSTRACT Frequencies of spontaneous and proflavine-induced frameshift mutations increase dramatically as a function of the number of reiterated base pairs at each of two sites in the lysozyme gene of bacteriophage T4. At each site, proflavine induces addition mutations more frequently than deletion mutations. We confirm that the steroidal diamine, irehdiamine A, induces frameshift addition mutations. At sites of reiterated bases, we propose that base pairing is misaligned adjacent to a gap. The misaligned configuration is stabilized by the stacking of mutagen molecules around the extrahelical base, forming a sandwich. Proflavine induces addition mutations efficiently at a site without any reiterated bases. Mutagenesis at such sites may be due to mutagen-induced stuttering of the replication complex.
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5

Nedu, Maria-Eliza, Mihaela Tertis, Cecilia Cristea, and Alexandru Valentin Georgescu. "Comparative Study Regarding the Properties of Methylene Blue and Proflavine and Their Optimal Concentrations for In Vitro and In Vivo Applications." Diagnostics 10, no. 4 (April 15, 2020): 223. http://dx.doi.org/10.3390/diagnostics10040223.

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Methylene blue and proflavine are fluorescent dyes used to stain nucleic acid from the molecular level to the tissue level. Already clinically used for sentinel node mapping, detection of neuroendocrine tumors, methemoglobinemia, septic shock, ifosfamide-induced encephalopathy, and photodynamic inactivation of RNA viruses, the antimicrobial, anti-inflammatory, and antioxidant effect of methylene blue has been demonstrated in different in vitro and in vivo studies. Proflavine was used as a disinfectant and bacteriostatic agent against many gram-positive bacteria, as well as a urinary antiseptic involved in highlighting cell nuclei. At the tissue level, the anti-inflammatory effects of methylene blue protect against pulmonary, renal, cardiac, pancreatic, ischemic-reperfusion lesions, and fevers. First used for their antiseptic and antiviral activity, respectively, methylene blue and proflavine turned out to be excellent dyes for diagnostic and treatment purposes. In vitro and in vivo studies demonstrated that both dyes are efficient as perfusion and tissue tracers and permitted to evaluate the minimal efficient concentration in different species, as well as their pharmacokinetics and toxicity. This review aims to identify the optimal concentrations of methylene blue and proflavine that can be used for in vivo experiments to highlight the vascularization of the skin in the case of a perforasome (both as a tissue tracer and in vascular mapping), as well as their effects on tissues. This review is intended to be a comparative and critical presentation of the possible applications of methylene blue (MB) and proflavine (PRO) in the surgical field, and the relevant biomedical findings from specialized literature to date are discussed as well.
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6

Goh, C. L. "Contact Sensitivity to Proflavine." International Journal of Dermatology 25, no. 7 (September 1986): 449. http://dx.doi.org/10.1111/j.1365-4362.1986.tb03451.x.

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7

Goh, C. L. "Occupational dermatitis from proflavine." Contact Dermatitis 17, no. 4 (October 1987): 256. http://dx.doi.org/10.1111/j.1600-0536.1987.tb02733.x.

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8

Ciatto, Carlo, Maria L. D’Amico, Giovanni Natile, Fernando Secco, and Marcella Venturini. "Intercalation of Proflavine and a Platinum Derivative of Proflavine into Double-Helical Poly(A)." Biophysical Journal 77, no. 5 (November 1999): 2717–24. http://dx.doi.org/10.1016/s0006-3495(99)77105-5.

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9

Biver, Tarita, Fernando Secco, Maria Rosaria Tinè, and Marcella Venturini. "Equilibria and kinetics of the intercalation of Pt-proflavine and proflavine into calf thymus DNA." Archives of Biochemistry and Biophysics 418, no. 1 (October 2003): 63–70. http://dx.doi.org/10.1016/s0003-9861(03)00384-9.

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10

Schoonheydt, Robert A., Jos Cenens, and Frans C. De Schrijver. "Spectroscopy of proflavine adsorbed on clays." Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases 82, no. 2 (1986): 281. http://dx.doi.org/10.1039/f19868200281.

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11

Sasikala, Wilbee D., and Arnab Mukherjee. "Structure and dynamics of proflavine association around DNA." Physical Chemistry Chemical Physics 18, no. 15 (2016): 10383–91. http://dx.doi.org/10.1039/c5cp07789c.

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12

Shemchuk, Oleksii, Dario Braga, Fabrizia Grepioni, and Raymond J. Turner. "Co-crystallization of antibacterials with inorganic salts: paving the way to activity enhancement." RSC Advances 10, no. 4 (2020): 2146–49. http://dx.doi.org/10.1039/c9ra10353h.

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Co-crystallization of the antibacterial agents proflavine and methyl viologen with the inorganic salts CuCl, CuCl2 and AgNO3 results in enhanced antimicrobial activity with respect to the separate components.
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13

Bhattar, S. L., G. B. Kolekar, and S. R. Patil. "FRET Between Anthracene and Proflavine Hemisulphate in Micellar Solution and Analytical Application on Determination of Proflavine Hemisulphate." Journal of Dispersion Science and Technology 32, no. 1 (December 21, 2010): 23–27. http://dx.doi.org/10.1080/01932690903543360.

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14

Wilmańska, Dorota, Malgorzata Czyz, Kazimierz Studzian, Mariola K. Piestrzeniewicz, and Marek Gniazdowski. "Effects of Anticancer Drugs on Transcription in vitro." Zeitschrift für Naturforschung C 56, no. 9-10 (October 1, 2001): 886–91. http://dx.doi.org/10.1515/znc-2001-9-1034.

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AbstractThe effects of DNA interacting drugs on: (1) total RNA synthesis catalyzed by E.coli and T7 RNA polymerase; (2) synthesis of the initiating dinucleotide (pppApU) by E .coli RNA polymerase (“abortive initiation“); (3) elongation of RNA chains synthesized by T7 RNA polymerase on pT7-7 plasmid DNA bearing T7 RNA polymerase promoter ϕ 10 with human Cu/Zn superoxide dismutase coding sequence, (4) interaction of transcription factor Sp1 and its binding site were studied. Intercalating ligands which form quickly dissociating complexes with DNA (anthracyclines, proflavine, ethidium bromide) are compared with the slowly dissociating drug of d(G · C ) specificity (actinomycin D), the non-intercalating, d(A · T ) specific pyrrole antibiotics (netropsin and distamycin A) and covalently binding to DNA 1-nitroacridine derivative (nitracrine). The obtained results indicate that rapidly dissociating ligands, proflavine and ethidium bromide, inhibit total RNA synthesis in vitro and the abortive initiation to a similar extent while they do not induce discrete elongation stops of RNA polymerase. Actinomycin D and nitracrine exhibit a high inhibitory effect on total RNA synthesis and induce stops of RNA polymerase while not affecting abortive initiation. Pyrrole antibiotics primarily inhibit the initiation, while no elongation stops are induced. Actinomycin D inhibits complex formation between nuclear proteins and the Sp1 binding site. Netropsin, ethidium bromide, proflavine and other intercalating acridines do not affect Sp1 binding. The results indicate that the effects primarily depend on sequence specificity and secondarily on the dissociation rate of ligands from their complexes with DNA.
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15

Sabolova, Danica, Pavol Kristian, and Mária Kozurkova. "Proflavine/acriflavine derivatives with versatile biological activities." Journal of Applied Toxicology 40, no. 1 (June 20, 2019): 64–71. http://dx.doi.org/10.1002/jat.3818.

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16

Girousi, Stella Th, Despina K. Alexiadou, and Andrea K. Ioannou. "An electroanalytical study of the drug proflavine." Microchimica Acta 160, no. 4 (July 16, 2007): 435–39. http://dx.doi.org/10.1007/s00604-007-0812-1.

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17

Neidle, S., L. H. Pearl, P. Herzyk, and H. M. Berman. "A molecular model for proflavine--DNA intercalation." Nucleic Acids Research 16, no. 18 (September 26, 1988): 8999–9016. http://dx.doi.org/10.1093/nar/16.18.8999.

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18

Ortona, Ornella, Lucia Costantino, Claudio Della Volpe, and Vincenzo Vitagliano. "Stacking equilibria of proflavine in various solutions." Journal of Molecular Liquids 45, no. 3-4 (April 1990): 201–11. http://dx.doi.org/10.1016/0167-7322(90)80030-n.

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19

Bonaca, A., and G. Bilalbegović. "Optical spectrum of proflavine and its ions." Chemical Physics Letters 493, no. 1-3 (June 2010): 33–36. http://dx.doi.org/10.1016/j.cplett.2010.05.003.

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20

Bandey, S. A., J. Atkins, and W. F. Neil. "Silastic foam dressing in pinnaplasty." Journal of Laryngology & Otology 100, no. 2 (February 1986): 201–2. http://dx.doi.org/10.1017/s0022215100098972.

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SummaryVarious forms of dressings, including proflavine wool, have been used traditionally for pinnaplasties.We report the use of Silastic Foam as a dressing in seven of our pinnaplasty cases. The advantages of Silastic Foam dressing over conventional dressings are mainly:1. Patient comfort.2. No change of dressing is required.
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21

Banassi, C. A., E. Scoffone, G. Galiazzo, and G. Iori. "PROFLAVINE-SENSITIZED PHOTOOXIDATION OF TRYPTOPHAN AND RELATED PEPTIDES." Photochemistry and Photobiology 6, no. 12 (June 28, 2008): 857–66. http://dx.doi.org/10.1111/j.1751-1097.1967.tb09650.x.

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22

Vlasova, N. N., L. P. Golovkova, N. G. Stukalina, and O. V. Markitan. "Interaction of nucleobases with proflavine on silica surface." Colloid Journal 75, no. 4 (July 2013): 373–77. http://dx.doi.org/10.1134/s1061933x13040170.

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23

Fiore, Cecilia, Oleksii Shemchuk, Fabrizia Grepioni, Raymond J. Turner, and Dario Braga. "Proflavine and zinc chloride “team chemistry”: combining antibacterial agents via solid-state interaction." CrystEngComm 23, no. 25 (2021): 4494–99. http://dx.doi.org/10.1039/d1ce00612f.

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Mechanochemical and solution reaction of ZnCl2 with proflavine yields the antimicrobials [HPF]2[ZnCl4]·H2O and ZnCl3(HPF), more active, with respect to the separate components and the AgNO3 standard, towards P. aeruginosa, E. coli and S. aureus.
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24

Pétusseau, Arthur F., Petr Bruza, and Brian W. Pogue. "Survey of X-ray induced Cherenkov excited fluorophores with potential for human use." Journal of Radiation Research 62, no. 5 (July 12, 2021): 833–40. http://dx.doi.org/10.1093/jrr/rrab055.

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Abstract X-ray induced molecular luminescence (XML) is a phenomenon that can be utilized for clinical, deep-tissue functional imaging of tailored molecular probes. In this study, a survey of common or clinically approved fluorophores was carried out for their megavoltage X-ray induced excitation and emission characteristics. We find that direct scintillation effects and Cherenkov generation are two possible ways to cause these molecules’ excitation. To distinguish the contributions of each excitation mechanism, we exploited the dependency of Cherenkov radiation yield on X-ray energy. The probes were irradiated by constant dose of 6 MV and 18 MV X-ray radiation, and their relative emission intensities and spectra were quantified for each X-ray energy pair. From the ratios of XML, yield for 6 MV and 18 MV irradiation we found that the Cherenkov radiation dominated as an excitation mechanism, except for aluminum phthalocyanine, which exhibited substantial scintillation. The highest emission yields were detected from fluorescein, proflavin and aluminum phthalocyanine, in that order. XML yield was found to be affected by the emission quantum yield, overlap of the fluorescence excitation and Cherenkov emission spectra, scintillation yield. Considering all these factors and XML emission spectrum respective to tissue optical window, aluminum phthalocyanine offers the best XML yield for deep tissue use, while fluorescein and proflavine are most useful for subcutaneous or superficial use.
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Radu, Liliana, B. Constantinescu, and Doina Gazdaru. "Effects of fast neutrons on chromatin: dependence on chromatin structure." Canadian Journal of Physiology and Pharmacology 80, no. 7 (July 1, 2002): 625–28. http://dx.doi.org/10.1139/y02-087.

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The effects of fast neutrons (10–100 Gy) on chromatin extracted from normal (liver of Wistar rats) and tumor (Walker carcinosarcoma maintained on Wistar rats) tissues were compared. The spectroscopic assays used were (i) chromatin intrinsic fluorescence, (ii) time-resolved fluorescence of chromatin – proflavine complexes, and (iii) fluorescence resonance energy transfer (FRET) between dansyl chloride and acridine orange coupled to chromatin. For both normal and tumor chromatin, the intensity of intrinsic fluorescence specific for acidic and basic proteins decreased with increasing dose. The relative contributions of the excited-state lifetime of proflavine bound to chromatin were reduced upon fast-neutron irradiation, indicating a decrease in the proportion of chromatin DNA available for ligand binding. The Förster energy transfer efficiencies were also modified by irradiation. These effects were larger for chromatin from tumor tissue. In the range 0–100 Gy, fast neutrons induced alterations in DNA and acidic and basic proteins, as well as in global chromatin structure. The radiosensitivity of chromatin extracted from tumor tissue seems to be higher than that of chromatin extracted from normal tissue, probably because of its higher euchromatin (loose) – heterochromatin (compact) ratio.Key words: chromatin structure, normal and tumor tissues, fast neutrons, spectrofluorimetric methods.
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26

Bonaca, A., and G. Bilalbegović. "Electronic absorption spectra of hydrogenated protonated naphthalene and proflavine." Monthly Notices of the Royal Astronomical Society 416, no. 2 (July 19, 2011): 1509–13. http://dx.doi.org/10.1111/j.1365-2966.2011.19149.x.

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27

Shah, Kiramat, Hamna Shadab, Muhammad Raza Shah, and Zahid Hussain Soomro. "Selective Chemosensor for Proflavine Dye Based on Fluorene Derivative." Sensor Letters 14, no. 2 (February 1, 2016): 153–58. http://dx.doi.org/10.1166/sl.2016.3608.

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28

Gajiwala, Himansu M., and Robert Zand. "Synthesis and Characterization of 3,6-Diaminoacridine (Proflavine) Containing Polyimides." Macromolecules 28, no. 2 (March 1995): 481–85. http://dx.doi.org/10.1021/ma00106a010.

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29

Bereznyak, E. G., N. A. Gladkovskaya, A. S. Khrebtova, E. V. Dukhopelnikov, and A. V. Zinchenko. "Peculiarities of DNA-proflavine binding under different concentration ratios." Biophysics 54, no. 5 (October 2009): 574–80. http://dx.doi.org/10.1134/s0006350909050030.

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30

Basu, Anirban, and Gopinatha Suresh Kumar. "Thermodynamic characterization of proflavine–DNA binding through microcalorimetric studies." Journal of Chemical Thermodynamics 87 (August 2015): 1–7. http://dx.doi.org/10.1016/j.jct.2015.03.009.

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31

Choudhury, Molina, and Rama Basu. "Studies of charge transfer interaction of nucleotides with proflavine." Journal of Photochemistry and Photobiology A: Chemistry 85, no. 1-2 (January 1995): 89–92. http://dx.doi.org/10.1016/1010-6030(94)03888-2.

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32

Garin, Dominique, Fatima Oukhatar, Andrew B. Mahon, Andrew C. Try, Michel Dubois-Dauphin, Frank M. Laferla, Martine Demeunynck, Marcelle Moulin Sallanon, and Sabine Chierici. "Proflavine derivatives as fluorescent imaging agents of amyloid deposits." Bioorganic & Medicinal Chemistry Letters 21, no. 8 (April 2011): 2203–6. http://dx.doi.org/10.1016/j.bmcl.2011.03.010.

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33

Robinson, Sarah M., Zuliang Shen, Jon R. Askim, Christopher B. Montgomery, Herman O. Sintim, and Steve Semancik. "Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform." Biosensors 9, no. 2 (April 12, 2019): 54. http://dx.doi.org/10.3390/bios9020054.

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Development of technologies for rapid screening of DNA secondary structure thermal stability and the effects on stability for binding of small molecule drugs is important to the drug discovery process. In this report, we describe the capabilities of an electrochemical, microdevice-based approach for determining the melting temperatures (Tm) of electrode-bound duplex DNA structures. We also highlight new features of the technology that are compatible with array development and adaptation for high-throughput screening. As a foundational study to exhibit device performance and capabilities, melting-curve analyses were performed on 12-mer DNA duplexes in the presence/absence of two binding ligands: diminazene aceturate (DMZ) and proflavine. By measuring electrochemical current as a function of temperature, our measurement platform has the ability to determine the effect of binding ligands on Tm values with high signal-to-noise ratios and good reproducibility. We also demonstrate that heating our three-electrode cell with either an embedded microheater or a thermoelectric module produces similar results. The ΔTm values we report show the stabilizing ability of DMZ and proflavine when bound to duplex DNA structures. These initial proof-of-concept studies highlight the operating characteristics of the microdevice platform and the potential for future application toward other immobilized samples.
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Janovec, Ladislav, Eva Kovacova, Martina Semelakova, Monika Kvakova, Daniel Kupka, David Jager, and Maria Kozurkova. "Synthesis of Novel Biologically Active Proflavine Ureas Designed on the Basis of Predicted Entropy Changes." Molecules 26, no. 16 (August 11, 2021): 4860. http://dx.doi.org/10.3390/molecules26164860.

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A novel series of proflavine ureas, derivatives 11a–11i, were synthesized on the basis of molecular modeling design studies. The structure of the novel ureas was obtained from the pharmacological model, the parameters of which were determined from studies of the structure-activity relationship of previously prepared proflavine ureas bearing n-alkyl chains. The lipophilicity (LogP) and the changes in the standard entropy (ΔS°) of the urea models, the input parameters of the pharmacological model, were determined using quantum mechanics and cheminformatics. The anticancer activity of the synthesized derivatives was evaluated against NCI-60 human cancer cell lines. The urea derivatives azepyl 11b, phenyl 11c and phenylethyl 11f displayed the highest levels of anticancer activity, although the results were only a slight improvement over the hexyl urea, derivative 11j, which was reported in a previous publication. Several of the novel urea derivatives displayed GI50 values against the HCT-116 cancer cell line, which suggest the cytostatic effect of the compounds azepyl 11b–0.44 μM, phenyl 11c–0.23 μM, phenylethyl 11f–0.35 μM and hexyl 11j–0.36 μM. In contrast, the novel urea derivatives 11b, 11c and 11f exhibited levels of cytotoxicity three orders of magnitude lower than that of hexyl urea 11j or amsacrine.
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García, Begoña, José M. Leal, Vittorio Paiotta, Rebeca Ruiz, Fernando Secco, and Marcella Venturini. "Role of the Third Strand in the Binding of Proflavine and Pt-Proflavine to Poly(rA)·2poly(rU): A Thermodynamic and Kinetic Study." Journal of Physical Chemistry B 112, no. 23 (June 2008): 7132–39. http://dx.doi.org/10.1021/jp800163n.

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Schneider, B., S. L. Ginell, and H. M. Berman. "Low temperature structures of dCpG-proflavine. Conformational and hydration effects." Biophysical Journal 63, no. 6 (December 1992): 1572–78. http://dx.doi.org/10.1016/s0006-3495(92)81755-1.

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37

Kemp, Sharon, Nial J. Wheate, Frank H. Stootman, and Janice R. Aldrich-Wright. "The Host-Guest Chemistry of Proflavine with Cucurbit[6,7,8]urils." Supramolecular Chemistry 19, no. 7 (October 1, 2007): 475–84. http://dx.doi.org/10.1080/10610270601124019.

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38

Swenberg, Charles E., Susan E. Carberry, and Nicholas E. Geacintov. "Linear dichroism characteristics of ethidium-and proflavine-supercoiled DNA complexes." Biopolymers 29, no. 14 (December 1990): 1735–44. http://dx.doi.org/10.1002/bip.360291406.

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Bailly, Christian, William Laine, Martine Demeunynck, and Jean Lhomme. "Enantiospecific Recognition of DNA Sequences by a Proflavine Tröger Base." Biochemical and Biophysical Research Communications 273, no. 2 (July 2000): 681–85. http://dx.doi.org/10.1006/bbrc.2000.2997.

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40

Nam, Dong Heon, and Chan Beum Park. "Visible Light-Driven NADH Regeneration Sensitized by Proflavine for Biocatalysis." ChemBioChem 13, no. 9 (May 3, 2012): 1278–82. http://dx.doi.org/10.1002/cbic.201200115.

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41

Buchelnikov, Anatoly S., Galina I. Dovbeshko, Dmitry P. Voronin, Vladimir V. Trachevsky, Viktor V. Kostjukov, and Maxim P. Evstigneev. "Spectroscopic Study of Proflavine Adsorption on the Carbon Nanotube Surface." Applied Spectroscopy 68, no. 2 (February 2014): 232–37. http://dx.doi.org/10.1366/13-07205.

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42

More, Vishalkumar R., Prashant V. Anbhule, Sang H. Lee, Shivajirao R. Patil, and Govind B. Kolekar. "Fluorimetric Study on the Interaction between Norfloxacin and Proflavine Hemisulphate." Journal of Fluorescence 21, no. 4 (March 30, 2011): 1789–96. http://dx.doi.org/10.1007/s10895-011-0873-8.

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43

Polyanskaya, Tatyana V., Irene Kazhdan, D. Michelle Motley, and Judith A. Walmsley. "Synthesis, characterization and cytotoxicity studies of palladium(II)–proflavine complexes." Journal of Inorganic Biochemistry 104, no. 11 (November 2010): 1205–13. http://dx.doi.org/10.1016/j.jinorgbio.2010.07.010.

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Ancel, Laetitia, Christelle Gateau, Colette Lebrun, and Pascale Delangle. "DNA Sensing by a Eu-Binding Peptide Containing a Proflavine Unit." Inorganic Chemistry 52, no. 2 (January 4, 2013): 552–54. http://dx.doi.org/10.1021/ic302456q.

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ASLANOGLU, Mehmet. "Electrochemical and Spectroscopic Studies of the Interaction of Proflavine with DNA." Analytical Sciences 22, no. 3 (2006): 439–43. http://dx.doi.org/10.2116/analsci.22.439.

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Kim, Kwang S., and E. Clementi. "Energetics and pattern analysis of crystals of proflavine deoxydinucleoside phosphate complex." Journal of the American Chemical Society 107, no. 1 (January 1985): 227–34. http://dx.doi.org/10.1021/ja00287a041.

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Horowitz, Eric D., and Nicholas V. Hud. "Ethidium and Proflavine Binding to a 2‘,5‘-Linked RNA Duplex." Journal of the American Chemical Society 128, no. 48 (December 2006): 15380–81. http://dx.doi.org/10.1021/ja065339l.

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Baldeyrou, Brigitte, Christelle Tardy, Christian Bailly, Pierre Colson, Claude Houssier, Franck Charmantray, and Martine Demeunynck. "Synthesis and DNA interaction of a mixed proflavine–phenanthroline Tröger base." European Journal of Medicinal Chemistry 37, no. 4 (April 2002): 315–22. http://dx.doi.org/10.1016/s0223-5234(02)01356-9.

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Inanobe, Atsushi, Hideaki Itamochi, and Yoshihisa Kurachi. "Kir Channel Blockages by Proflavine Derivatives via Multiple Modes of Interaction." Molecular Pharmacology 93, no. 6 (April 12, 2018): 592–600. http://dx.doi.org/10.1124/mol.117.111377.

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Jin, Biao, Gi Woong Sung, and Yoon Jung Jang. "Binding mode of proflavine to DNA probed by polarized light spectroscopy." Journal of the Chinese Chemical Society 66, no. 4 (November 20, 2018): 391–95. http://dx.doi.org/10.1002/jccs.201800246.

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