Academic literature on the topic 'Profound hypoglycaemia'

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Journal articles on the topic "Profound hypoglycaemia"

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Schiemsky, Toon, Kathleen Croes, Pieter Vermeersch, et al. "An unconscious man with profound drug-induced hypoglycaemia." Biochemia medica 30, no. 1 (2020): 143–48. http://dx.doi.org/10.11613/bm.2020.010802.

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Introduction: Hypoglycaemia has been reported as an unusual complication of tramadol use and in a few cases of tramadol poisoning, but the exact mechanism is not known. Case description: An ambulance crew was dispatched to an unconscious 46-year old man. A glucometer point-of-care measurement revealed a profound hypoglycaemia (1.9 mmol/L). Treatment with intravenous glucose was started and the patient was transported to the hospital. The patient had several episodes of pulseless electrical activity requiring cardiopulmonary resuscitation in the ambulance and upon arrival in the hospital. Despi
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Croxson, Simon C. M., Remy McConvey, and Louise Molodynski. "Profound hypoglycaemia and cognitive impairment." Practical Diabetes International 18, no. 9 (2001): 315–16. http://dx.doi.org/10.1002/pdi.271.

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Frankton, Sarah, Suhail Baithun, Ehab Husain, Katherine Davis, and Ashley Grossman. "Phaeochromocytoma crisis presenting with profound hypoglycaemia and subsequent hypertension." HORMONES 8, no. 1 (2009): 65–70. http://dx.doi.org/10.14310/horm.2002.1224.

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Kanbour, Sarah, Aanika Balaji, Kacey Chae, and Nestoras Mathioudakis. "Insulinoma mimic: methadone-induced hypoglycaemia." BMJ Case Reports 15, no. 7 (2022): e245890. http://dx.doi.org/10.1136/bcr-2021-245890.

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Methadone use for opioid use disorder and chronic pain has increased since the start of the century with about 4.4 million dispensed prescriptions in 2009. With increased use of methadone, there has been increasing reporting of less commonly reported side effects (ie, hypoglycaemia). Here, we describe a woman in her 70s with history of opioid use disorder on methadone, stage 4 chronic kidney disease and prior hypoglycaemic episodes who initially presented with perforated gastric ulcer requiring surgical repair. Her perioperative course was complicated by profound hyperinsulinaemic hypoglycaemi
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Fraser, R., J. Fuller, M. Horowitz, and J. Dent. "Effect of insulin-induced hypoglycaemia on antral, pyloric and duodenal motility in fasting subjects." Clinical Science 81, no. 2 (1991): 281–85. http://dx.doi.org/10.1042/cs0810281.

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1. Hyperglycaemia alters gastric motility and delays gastric emptying. By contrast, there is little information regarding the effect of sub-normal blood glucose concentrations on gastric and, in particular, pyloric motility, although limited data suggest that hypoglycaemia is associated with accelerated gastric emptying despite an apparently increased basal pyloric pressure. 2. To determine the effects of hypoglycaemia on pyloric motility, we compared the effects of an intravenous injection of insulin (0.15 units/kg) with those of a placebo injection of saline in eight healthy human volunteers
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Smith, Jay. "Hypoglycaemic Coma Associated with Anorexia Nervosa." Australian & New Zealand Journal of Psychiatry 22, no. 4 (1988): 448–53. http://dx.doi.org/10.3109/00048678809161355.

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Profound hypoglycaemia is a rare event which has been described in seven cases of anorexia nervosa. A further case is reported here and the literature regarding this complication is reviewed. The major risk factors identified are body weight below 30 kg, a period of fasting and intercurrent infection. Excessive exercise may also play a role. The precise pathogenesis has not been elucidated but several mechanisms, including depletion of liver glycogen, defective gluconeogenesis or failure of glucagon secretion have been proposed. Although hypoglycaemic coma frequently results in death, prompt t
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Dunne, Thomas Frederick, Tarekegn Geberhiwot, and Rowena Jones. "Acute psychosis in glycogen storage disease: a rare but severe complication." BMJ Case Reports 12, no. 7 (2019): e222307. http://dx.doi.org/10.1136/bcr-2017-222307.

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Glycogen storage disease type 1 (GSD-1) is a group of inherited metabolic disorders characterised by the inability to use intracellular glucose stores. It is associated with a high risk of hypoglycaemia, as well as long-term complications including growth retardation, hepatocellular adenomas, renal disease, hypertriglyceridaemia and hyperuricaemia. Treatment involves slow absorption carbohydrates, for example, cornstarch. We present a case of acute psychosis in a patient with GSD-1a. This was initially attributed to his opiate use. Later in his management an MRI scan of his head was performed
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Waring, W. S., and W. D. Alexander. "Emergency Presentation of an Elderly Female Patient with Profound Hypoglycaemia." Scottish Medical Journal 49, no. 3 (2004): 105–7. http://dx.doi.org/10.1177/003693300404900311.

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Ezeanochie, Michael, Oghenefegor Olokor, and Ofure Yamah. "Sickle cell anaemia in vaso-occlusive crisis and acute fatty liver of pregnancy: a case report." Ghana Medical Journal 54, no. 3 (2020): 201–3. http://dx.doi.org/10.4314/gmj.v54i3.12.

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Acute fatty liver of pregnancy (AFLP) is an uncommon condition that manifests in the third trimester of pregnancy.Its association with vaso-occlusive crisis from Sickle Cell Anaemia is not common. Published data on the simultaneous occurrence of these two conditions is rare, hence this case report. A 32-year-old gravida 3 para 1+1 lady, with Sickle Cell Anaemia, had a vaso-occlusive crisis in association with AFLP at 32 weeks’ gestation, and the outcome of her management was successful. AFLP is a rare late-gestational event affecting about 1 in 10,000 to 15,000 pregnancies. The exact aetiology
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Saluja, Sushant, and Edward Bernard Jude. "Hypoglycaemia as a cause of dynamic ECG changes: recognition and management." BMJ Case Reports 18, no. 5 (2025): e265603. https://doi.org/10.1136/bcr-2025-265603.

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An elderly man with type 2 diabetes on two times per day biphasic insulin presented after a fall in the toilet, preceded by reduced intake and transient loss of consciousness. Paramedics found profound hypoglycaemia (capillary blood glucose (BG) – 0.9 mmol/L) and administered intravenous glucose, raising BG to 7.2 mmol/L. In the emergency department, he experienced recurrent hypoglycaemia (BG 1.8 and 2.6 mmol/L). ECG revealed T-wave abnormalities and QT prolongation, raising concerns for myocardial ischaemia or arrhythmia. Troponin was mildly elevated (14 ng/L), but he remained haemodynamicall
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Books on the topic "Profound hypoglycaemia"

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Mesotten, Dieter, and Sophie Van Cromphaut. Management of diabetic emergencies in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0260.

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The three major diabetic emergencies comprise diabetic ketoacidosis (DKA), hyperglycaemic hyperosmolar state (HHS), and prolonged hypoglycaemia. These complications are preventable, treatable, and rather infrequently lead to prolonged intensive care (ICU) admission. Hyperglycaemic crises, whether DKA in type 1 diabetics, or HHS in type 2 diabetics, are characterized by moderate to severe hypovolaemia, electrolyte disturbances and a potentially life-threatening trigger. Hence, airway–breathing–circulation securement, diagnosis, and treatment of the underlying condition, as well as fluid resusci
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Debaveye, Yves, Dieter Mesotten, and Greet Van den Berghe. Hyperglycaemia, diabetes, and other endocrine emergencies. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0069.

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Although endocrine pathology is usually treated in outpatient clinic, intensive care may be required when endocrinopathies are associated with other medical illnesses or reach a state of decompensation. Although endocrine emergencies are quite rare, they are potentially life-threatening, if not recognized promptly and managed effectively. Therefore, every clinician should always be attentive to a possible diagnosis of these complex disorders. The three major diabetic emergencies comprise diabetic ketoacidosis, hyperglycaemic hyperosmolar state, and prolonged hypoglycaemia. Hyperglycaemic crise
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Book chapters on the topic "Profound hypoglycaemia"

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Gunst, Jan, Yves Debaveye, and Greet Van den Berghe. "Stress hyperglycaemia and endocrine emergencies." In The ESC Textbook of Intensive and Acute Cardiovascular Care, edited by Marco Tubaro, Pascal Vranckx, Eric Bonnefoy-Cudraz, Susanna Price, and Christiaan Vrints. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198849346.003.0068.

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Although endocrine pathology is usually treated in an outpatient clinic, intensive care may be required when endocrinopathies are associated with other medical illnesses or reach a state of decompensation. Although endocrine emergencies are quite rare, they are potentially life-threatening if not recognised promptly and managed effectively. Therefore, every clinician should always be attentive to a possible diagnosis of these complex disorders. The three major diabetic emergencies comprise diabetic ketoacidosis, hyperglycaemic hyperosmolar state, and prolonged hypoglycaemia. Hyperglycaemic cri
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Cummings, David E. "Metabolic surgery in the treatment of type 2 diabetes mellitus." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1416.

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Faced with the dual pandemics of obesity and type 2 diabetes mellitus, heath care providers require a broad array of treatment options. Diet, exercise, and medications remain the cornerstones of type 2 diabetes therapy, but long-term results with lifestyle modifications can be disappointing, and, despite an ever-increasing armamentarium of pharmacotherapeutics, adequate glycaemic control often remains elusive. Moreover, most diabetes medications promote weight gain, and using them to achieve tight glycaemic control introduces a proportionate risk of hypoglycaemia. In cases where behavioural/ph
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Ismail, Khalida, Chris Garrett, and Marietta Stadler. "Type 1 Diabetes and Psychiatry." In Oxford Textbook of Endocrinology and Diabetes 3e, edited by John A. H. Wass, Wiebke Arlt, and Robert K. Semple. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198870197.003.0273.

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There is a consistent pattern of association of several psychiatric disorders and type 1 diabetes (T1D) including depression, anxiety, eating disorders, and personality disorders. The presumption is that most psychiatric morbidity is accrued from the psychological burden per se of T1D or that individuals with subclinical pre-existing mental health difficulties are tipped into an overt psychiatric diagnosis. Elements of the T1D regime, namely the acute focus on food and the energy it contains, as well as heightened requirements of self-control can predispose to eating disorders, while others fi
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