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Journal articles on the topic 'Progesterone Levels'

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Published: 2 June 2025

Last updated: 31 July 2025

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1

Jerat, Sandra, and Susan Kaufman. "Effect of pregnancy and steroid hormones on plasma adrenomedullin levels in the rat." Canadian Journal of Physiology and Pharmacology 76, no. 4 (1998): 463–66. http://dx.doi.org/10.1139/y98-113.

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Pregnancy is characterized by volumeexpansion and vasodilation. We investigated whether thehypotensive peptide adrenomedullin (ADM) might be a significantfactor in the cardiovascular adaptation to pregnancy. Rats wereprepared with indwelling cannulae. Plasma ADM levels weremeasured by RIA before mating, at 7, 14, and 21 days ofpregnancy, and at 7 days postpartum. We also investigated theeffects on plasma ADM levels of administering estrogen,progesterone, and the metabolite of progesterone3-OH-5-pregnan-20-one(3-OH-DHP); this last steroid has been implicated inaltering reflex control of blood p

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Szrok-Jurga, Sylwia, Jacek Turyn, Julian Swierczynski, Wiktoria Stelmanska, Malgorzata Presler, and Ewa Stelmanska. "Gender-Dependent Effect of Progesterone on the Expression of Metallothionein Genes in Rat Inguinal Adipose Tissue." International Journal of Molecular Sciences 26, no. 9 (2025): 4066. https://doi.org/10.3390/ijms26094066.

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Metallothioneins (MTs) are low-molecular-weight metal-binding proteins potentially involved in the detoxification of heavy metals, protection against oxidative stress, and other biological processes. This study examined progesterone’s influence on Mt gene expression in rat adipose tissue. Wistar rats (females and males) received 100 mg of progesterone per rat. MT mRNA and protein levels were quantified by real-time PCR and Western blotting methods. Using radioimmunoassay, the serum progesterone level was measured. In this study, progesterone administration to female rats led to a 2.5-fold incr

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3

Nahoul, Khalil, and Dominique de Ziegler. "“Validity” of Serum Progesterone Levels After Oral Progesterone." Fertility and Sterility 61, no. 4 (1994): 790–91. http://dx.doi.org/10.1016/s0015-0282(16)56666-7.

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4

Lisnawati, Yuyun, Noroyono Wibowo, and Ana Mariana. "Correlation of cervical progesterone levels to plasma progesterone levels in normal pregnancy and preterm labor: A cross-sectional study." F1000Research 8 (February 15, 2019): 189. http://dx.doi.org/10.12688/f1000research.17525.1.

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Background: Theory of “functional progesterone withdrawal” explains the role of progesterone prior to delivery. Previous studies mentioned the existence of progesterone regulation in the cervix that plays a role in maintaining the integrity of the cervix and cervical ripening. Cervical progesterone levels relate to activities of progesterone at the cervix, compared to its amount in circulation. The objective of this study was to measure cervical mucus progesterone levels and its correlation to plasma progesterone levels in pregnancy. Methods: This was a cross sectional study conducted in Janua

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Lisnawati, Yuyun, and Noroyono Wibowo. "Correlation of cervical progesterone levels to plasma progesterone levels in normal pregnancy and preterm labor: A cross-sectional study." F1000Research 8 (October 25, 2022): 189. http://dx.doi.org/10.12688/f1000research.17525.2.

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Background: The theory of “functional progesterone withdrawal” explains the role of progesterone prior to delivery. Previous studies mentioned the existence of progesterone regulation in the cervix that plays a role in maintaining the integrity of the cervix and cervical ripening. Cervical progesterone levels relate to activities of progesterone at the cervix, compared to its amount in circulation. The objective of this study was to measure cervical mucus progesterone levels and its correlation to plasma progesterone levels in pregnancy. Methods: This was a cross-sectional study conducted in J

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Rybkin, I., G. Bareh, K. Wei, J. D. Jacobson, J. Corselli, and P. J. Chan. "Progesterone levels and IVF pregnancy." Fertility and Sterility 106, no. 3 (2016): e336. http://dx.doi.org/10.1016/j.fertnstert.2016.07.952.

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7

KIRLANGIÇ, Mehmet Mete, Mefkure ERASLAN ŞAHİN, Merve VURAL YALMAN, et al. "Polikistik over sendromlu obez olmayan kadınlarda progesteron ve progesteron kaynaklı bloke edici faktör (PIBF) düzeyleri." Cukurova Medical Journal 47, no. 3 (2022): 1114–20. http://dx.doi.org/10.17826/cumj.1121724.

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Purpose: This study aimed to evaluate the level of progesterone and progesterone-induced blocking factor (PIBF), an immune mediator, in non-obese patients with polycystic ovary syndrome (PCOS). Materials and Methods: Totally 72 patients were recruited into study and divided into 2 groups: The first group was patients diagnosed with PCOS (n = 36) and the second was the healthy control group (n=36). The diagnosis of PCOS was made according to Rotterdam diagnostic criteria. All patients were 18–35 years old and non-obese (body mass index (BMI) < 25 kg/m2). Follicle-stimulating hormone (F

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Cai, Zailong, and Carlos Stocco. "Expression and Regulation of Progestin Membrane Receptors in the Rat Corpus Luteum." Endocrinology 146, no. 12 (2005): 5522–32. http://dx.doi.org/10.1210/en.2005-0759.

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Despite evidence strongly supporting progesterone’s autocrine actions in the rat corpus luteum (CL), classical progesterone receptors (PR) have not been detected in this gland. Alternatively, in several other systems, progestins have been reported to activate nongenomic pathways via putative progestin membrane receptors (PMRs). The aim of this investigation was to determine whether rat CL membranes bind progestins and contain PMR homologs and whether these proteins are expressed during CL development in a manner that parallels luteal function. We found that luteal cell membranes specifically b

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9

Mlaco, N., A. Katica, B. Cengic, and V. Sakic. "Results of applying gonadorelin Fertagyl on the progesterone concentrations in the blood serum and cow conception." Biotehnologija u stocarstvu 29, no. 1 (2013): 19–28. http://dx.doi.org/10.2298/bah1301019m.

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Considering there are different and inconsistent results of the wider use of gonadotropin-releasing hormone or its analogs in cattle breeding and due to scarce research studies in the field of individual breeding, we decided to explore the influence of gonadorelin Fertagyl on the results of the blood serum progesterone levels and conception of cows in veterinary field practice. Examination of the progesterone levels involved 14 (fourteen) cows treated with gonadorelin (GnRH), Fertagyl, manufactured by Intervet, according to the manufacturer?s instructions dose of 2,5ml (250 micrograms), within

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Kareem Juhi, Ali, and Aliaa Saadoon Abdul- Razzaq Al-Faraji. "Measuring levels of hormones in osteoporosis Iraqi women patients." Bionatura 8, no. 1 (2023): 1–3. http://dx.doi.org/10.21931/rb/2023.08.01.85.

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This study was conducted to investigate the effect of the hormone progesterone and testosterone on osteoporosis in women, and it was found that there are statistically significant differences between the hormone progesterone and there are no statistically significant differences for the hormone testosterone. The ELISA method measured the testosterone concentration in the blood and the progesterone concentration. The purpose of the study measuring the levels of some hormones in osteoporosis Iraqi women patients. Fifty (50) women patients with osteoporosis were admitting Baghdad Teaching Hospita

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11

Devarajan, Nayana, Shibu Simon, C. Jayakumar, et al. "Progesterone and Prostaglandin F metabolite levels in relation to modes of whelping." Journal of Veterinary and animal sciences 55, no. 4 (2024): 739–43. https://doi.org/10.51966/jvas.2024.55.4.739-743.

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Parturition involves a series of changes in the blood levels of various hormones. The present study aimed to examine the concentrations of progesterone and 15-ketodihydroprostaglandin F2α or PGFM (prostaglandin F metabolite) hormones on the day of delivery across different modes of whelping. Bitches that underwent vaginal whelping (VW) (Group I), elective caesarean section (CS) (Group II), emergency CS (Group III) and mifepristone primed whelping (Group IV) presented to University Veterinary Hospitals, Kokkalai and Mannuthy constituted the material for the present study. The study enrolled a t

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Panjaitan, Budianto, Citra Chyntia Helwana, Nellita Meutia, et al. "Hubungan Kadar Progesteron pada Fase Awal Luteal dengan Kematian Embrio pada Sapi Aceh." Jurnal Agripet 19, no. 2 (2019): 107–12. http://dx.doi.org/10.17969/agripet.v19i2.14881.

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ABSTRAK. Progesteron merupakan hormon yang berperan penting dalam proses pemeliharaan kebuntingan dan dihasilkan oleh corpus luteum. Penelitian ini bertujuan mengetahui hubungan antara kadar hormon progesteron pada fase awal luteal dengan kematian embrio pada sapi Aceh. Dalam penelitian ini digunakan empat ekor sapi betina dewasa berumur 3-5 tahun, bobot badan 150-250 kg, sehat secara klinis, dan memiliki reproduksi normal. Sapi disinkronisasi menggunakan 5 ml prostaglandin F2 alfa (PGF2α) dengan pola penyuntikan ganda berinterval 11 hari. Koleksi sampel darah untuk pengukuran konsentrasi prog

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Kawabe, K., Y. Yoshii, K. Ikeda, and Y. Iwasaki. "Progesterone levels in amyotrophic lateral sclerosis." Acta Neurologica Scandinavica 124, no. 5 (2011): 359. http://dx.doi.org/10.1111/j.1600-0404.2011.01531.x.

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Núñez-de la Mora, Alejandra, Robert T. Chatterton, Osul A. Choudhury, Dora A. Napolitano, and Gillian R. Bentley. "Childhood Conditions Influence Adult Progesterone Levels." PLoS Medicine 4, no. 5 (2007): e167. http://dx.doi.org/10.1371/journal.pmed.0040167.

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15

Rose, David P., Kathryn Tilton, Heli Lahtis, and Ernst L. Wynders. "Progesterone levels in breast duct fluid." European Journal of Cancer and Clinical Oncology 22, no. 1 (1986): 111–13. http://dx.doi.org/10.1016/0277-5379(86)90350-0.

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16

TSUNODA, NOBUO, HIROAKI AKITA, KIYOSHI MIYAZAWA, et al. "Progesterone Levels in the Serum of Mares Determined by Progesterone ELISA Kit." Journal of the Japan Veterinary Medical Association 42, no. 11 (1989): 759–62. http://dx.doi.org/10.12935/jvma1951.42.759.

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17

Martel, D., M. N. Monier, D. Roche, V. J. De Feo, and A. Psychoyos. "Hormonal dependence of the metrial gland: further studies on oestradiol and progesterone receptor levels in the rat." Journal of Endocrinology 120, no. 3 (1989): 465–72. http://dx.doi.org/10.1677/joe.0.1200465.

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ABSTRACT The main objective of the present study was to analyse the hormonal dependence of the metrial gland formed in pseudopregnant animals following massive decidualization. On day 13 of pseudopregnancy (when the metrial gland reaches its maximal development) animals were ovariectomized and given s.c. implants of oestradiol and/or progesterone. A new implant technique for oestradiol delivery is described which provides circulating concentrations of oestradiol in the physiological range. In addition, we extended our previous work concerning oestradiol receptor and progesterone receptor conce

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18

Martínez-Montoro, José Ignacio, María Molina-Vega, Maite Asenjo-Plaza, et al. "Adiposity is Associated with Decreased Serum 17-Hydroxyprogesterone Levels in Non-Diabetic Obese Men Aged 18–49: A Cross-Sectional Study." Journal of Clinical Medicine 9, no. 12 (2020): 3873. http://dx.doi.org/10.3390/jcm9123873.

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Obesity is associated with decreased circulating testosterone levels, the main male sex hormone. However, there are a number of different male sex hormones whose dynamics remain poorly understood regarding this pathology. In this regard, 17 hydroxyprogesterone (17-OH progesterone), as an important precursor of testosterone synthetized in testes and adrenal glands, could play an essential role in testosterone deficiency in male obesity. Moreover, similarly to testosterone, 17-OH progesterone could be closely associated with visceral fat distribution and metabolic dysfunction. Thus, the aim of t

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19

Seki, Makoto, Norio Watanabe, Kenyo Ishii, et al. "Plasma progesterone profiles in Beagle bitches with and without the whelping experience." Acta Veterinaria Hungarica 58, no. 1 (2010): 117–24. http://dx.doi.org/10.1556/avet.58.2010.1.12.

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The aim of this study was to investigate differences between the progesterone profiles of Beagle bitches with (multiparous) and without (nulliparous) the whelping experience and to examine whether the selection of bitches by progesterone analyses before the programmed mating improved the whelping rates. In the first experiment, the progesterone profiles of nulliparous and multiparous bitches were evaluated from Days 1 to 13 (onset of prooestrus = Day 0). The mean duration of the elevation in progesterone levels (> 2 ng/mL) after the onset of prooestrus tended to be approximately 1 day short

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Ghasemzadeh, Alieh, Gilda Mostafavi, Mohammad Nouri, Parastoo Chaichi, Laya Farzadi, and Parvin Hakimi. "Survey of Relation between Midcycle Progesterone Level with IUI Cycles Success Rate." Advances in Bioscience and Clinical Medicine 7, no. 4 (2020): 9. http://dx.doi.org/10.7575/aiac.abcmed.v.7n.4p.9.

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Introduction: Assisted reproductive technology is used routinely for treatment of infertile spouses. Previous studies reported conflicting results regarding effect of progesterone rise at the HCG injection day. The aim of current study is to evaluate the effects of mid cycle progesterone levels in IUI cycles. Methods: In this analytical cross-sectional study, the outcome of treatment in 200 IUI cycles were evaluated. Patients’ demographic findings, progesterone level at the day of HCG injection, number of follicles >16 mm, endometrial thickness and clinical pregnancy rate were recorded. For

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Morissette, Marc, Daniel Lévesque, Alain Bélanger, and Thérèse Di Paolo. "A physiological dose of estradiol with progesterone affects striatum biogenic amines." Canadian Journal of Physiology and Pharmacology 68, no. 12 (1990): 1520–26. http://dx.doi.org/10.1139/y90-231.

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The acute effect of estradiol and progesterone on dopamine and serotonin metabolism in rat striatum was studied. One subcutaneous injection of 17β-estradiol (300 ng) and progesterone (150 μg) into intact male rats increased plasma levels of these steroids, while testosterone, corticosterone, and estrone remained unchanged. Dehydroepiandrosterone, androstane-3β, 17β-diol and dihydrotestosterone remained undetectably low. Prolactin decreased and androstane-3α,17β-diol, and 17-OH progesterone increased, but less than estradiol and progesterone. Peak levels of striatal dopamine, dihydroxyphenylace

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Aleksandrov, A., V. Konopelniuk, and L. Ostapchenko. "Peripheral serotonin and tryptophan levels in rats under progesterone long-term administration." Bulletin of Taras Shevchenko National University of Kyiv. Series: Problems of Physiological Functions Regulation 20, no. 1 (2016): 5–7. http://dx.doi.org/10.17721/2616_6410.2016.20.5-7.

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Tryptophan and serotonin levels in duodenum mucosa and blood serum of rats under progesterone long-term administration have been determined. The studies show that tryptophan and the serotonin content increase in rats under progesterone long-term administration compared with control group of rats. Obtained data give evidence that biosynthetic pathway of serotonin, particularly, content of serotonin, is involved in the obesity development induced by progesterone long-term administration.

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Hornung, Rebecca S., Namrata GR Raut, Daisy J. Cantu, Lauren M. Lockhart, and Dayna L. Averitt. "Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone." Molecular Pain 18 (January 2022): 174480692110692. http://dx.doi.org/10.1177/17448069211069255.

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Orofacial pain disorders are predominately experienced by women. Progesterone, a major ovarian hormone, is neuroprotective and antinociceptive. We recently reported that progesterone attenuates estrogen-exacerbated orofacial pain behaviors, yet it remains unclear what anatomical substrate underlies progesterone’s activity in the trigeminal system. Progesterone has been reported to exert protective effects through actions at intracellular progesterone receptors (iPR), membrane-progesterone receptors (mPR), or sigma 1 receptors (Sig-1R). Of these, the iPR and Sig-1R have been reported to have a

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Handito Sarwwotatwadhiko, Widyanti Soewoto, and Ida Bagus Budhi Surya. "Evaluating Progesterone Level Fluctuations as a Response Indicator to Chemotherapy in Triple Negative Breast Cancer." Bioscientia Medicina : Journal of Biomedicine and Translational Research 9, no. 7 (2025): 8033–44. https://doi.org/10.37275/bsm.v9i7.1334.

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Background: Triple negative breast cancer (TNBC) represents an aggressive subtype with limited targeted therapies and often poorer prognosis. Chemotherapy remains a cornerstone of treatment, yet its systemic effects, including hormonal alterations, are not fully elucidated. The role of progesterone in TNBC progression and its modulation by chemotherapy is particularly complex and warrants investigation. This study aimed to evaluate changes in serum progesterone levels following chemotherapy in TNBC patients. Methods: A prospective cohort study was conducted at Dr. Moewardi General Hospital, Su

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Tsompos, Constantinos, Constantinos Panoulis, Konstantinos Toutouzas, George Zografos, and Apostolos Papalois. "The Effect of Erythropoietin on Progesterone Levels during Ischemia Reperfusion Injury in Rats." Journal of South Asian Federation of Obstetrics and Gynaecology 6, no. 2 (2014): 65–70. http://dx.doi.org/10.5005/jp-journals-10006-1273.

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ABSTRACT The aim of this experiment was to study the effects of erythropoietin on rat model, particularly in ischemia reperfusion protocol. The beneficial or other effects of that molecule were studied estimating the mean blood progesterone levels. Materials and methods Forty rats were used of mean weight 247.7 gm. Progesterone levels were measured 60 minutes after reperfusion for groups A and C and 120 minutes after reperfusion for groups B and D. Groups A and B without the drug but C and D with erythropoietin administration. Results That erythropoietin administration nonsignificantly increas

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Kasambala, Hildegard R., Mwemezi J. Rwiza, and Robinson H. Mdegela. "Levels and distribution of progesterone in receiving waters and wastewaters of a growing urban area." Water Science and Technology 80, no. 6 (2019): 1107–17. http://dx.doi.org/10.2166/wst.2019.350.

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Abstract This study aimed at investigating the levels and distribution of progesterone in receiving waters and wastewaters in Arusha, a fast-growing urban area and the third largest city in Tanzania. Specifically, the study was conducted along the Themi River and the adjacent waste stabilization ponds (WSPs). Progesterone was detected and quantified by using an enzyme-linked immunosorbent assay (ELISA) kit. For Themi River samples, the level of progesterone obtained ranged from ‘no detection’ to 439 ng/L with a mean value of 120.3 ng/L. The levels detected were significantly higher in the mids

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Nidoieva, Z. M., and A. P. Latsyshyna. "Effect of progesterone on the MGMT gene expression in MCF7, HEp-2 and 293 cells." Visnik ukrains'kogo tovaristva genetikiv i selekcioneriv 18, no. 1-2 (2021): 16–21. http://dx.doi.org/10.7124/visnyk.utgis.18.1-2.1350.

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Aims: to investigate the steroid hormone progesterone effect on the human MGMT gene expression at the mRNA and protein levels in cell lines with different expression patterns of the nuclear progesterone receptors and membrane receptor PGRMC1. Methods: cell culture, RNA / protein isolation, cDNA synthesis, real-time polymerase chain reaction, Western blot analysis. Results: We observe the MGMT gene upregulation by progesterone at both mRNA and protein levels. Conclusions the effect of progesterone on MGMT expression is more complex than direct regulation through the classical nuclear receptor.K

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Habert, R., and R. Picon. "Relationships between plasma progesterone levels and testicular testosterone production in the rat fetus: effects of maternal ovariectomy." Journal of Endocrinology 108, no. 3 (1986): 361–67. http://dx.doi.org/10.1677/joe.0.1080361.

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ABSTRACT The present study was performed to examine whether circulating progesterone regulates testicular testosterone production in the fetal rat. Progesterone levels in fetal plasma were found to increase from day 14·5 to day 16·5; thereafter they reached a plateau between days 16·5 and 18·5 (80 nmol/l) and decreased threefold between days 18·5 and 21·5. The addition of progesterone, within the range of normal plasma concentrations, induced a dose-dependent increase in testosterone produced in vitro by the testes on days 16·5 and 18·5 but not on day 20·5. However, in 18·5-day-old fetuses, in

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Jahangard, Leila, Thorsten Mikoteit, Saman Bahiraei, et al. "Prenatal and Postnatal Hair Steroid Levels Predict Post-Partum Depression 12 Weeks after Delivery." Journal of Clinical Medicine 8, no. 9 (2019): 1290. http://dx.doi.org/10.3390/jcm8091290.

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Background: Within three to six months after delivery, 13%–19% of women suffer from post-partum depression (PPD), understood as a dysfunctional adaptation to the postpartum condition and motherhood. In the present cross-sectional study, we compared the hair steroid levels of women 12 weeks before and after delivery and with or without PPD. Method: The present study was a cross-sectional study conducted twelve weeks after delivery. At that time, 48 women (mean age: 25.9 years) with PPD and 50 healthy controls (mean age: 25.2 years) completed questionnaires on depressive symptoms. Further, at th

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Moshal, Karni S., Zhe Zhang, Karim Roder, et al. "Progesterone modulates SERCA2a expression and function in rabbit cardiomyocytes." American Journal of Physiology-Cell Physiology 307, no. 11 (2014): C1050—C1057. http://dx.doi.org/10.1152/ajpcell.00127.2014.

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We recently showed that progesterone treatment abolished arrhythmias and sudden cardiac death in a transgenic rabbit model of long QT syndrome type 2 (LQT2). Moreover, levels of cardiac sarco(endo)plasmic reticulum Ca2+-ATPase type 2a (SERCA2a) were upregulated in LQT2 heart extracts. We hypothesized that progesterone treatment upregulated SERCA2a expression, thereby reducing Ca2+-dependent arrhythmias in LQT2 rabbits. We therefore investigated the effect of progesterone on SERCA2a regulation in isolated cardiomyocytes. Cardiomyocytes from neonatal (3- to 5-day-old) rabbits were isolated, cult

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Stamatelou, Foteini, Efthimios Deligeoroglou, Georgios Farmakides, and Georgios Creatsas. "Abnormal Progesterone and Corticotropin Releasing Hormone Levels are Associated with Preterm Labour." Annals of the Academy of Medicine, Singapore 38, no. 11 (2009): 1011–16. http://dx.doi.org/10.47102/annals-acadmedsg.v38n11p1011.

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Introduction: This study examined whether maternal plasma progesterone and corticotropin releasing hormone (CRH) concentrations can predict the likelihood of preterm labour. Materials and Methods: Maternal plasma progesterone and CRH concentrations were examined in a total of 51 women. The subject cohort included 20 women who were followed from the beginning of the third trimester (28 to 34 weeks gestation), half of whom delivered early preterm and half of whom were not in labour and subsequently delivered at full term (n = 10 per group). In a follow-up experiment, 31 women who were admitted d

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&NA;. "Increased endometrial progesterone levels with vaginal administration." Inpharma Weekly &NA;, no. 956 (1994): 20. http://dx.doi.org/10.2165/00128413-199409560-00045.

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Gargiulo Monachelli, G., M. Meyer, G. E. Rodríguez, et al. "Response: progesterone levels in amyotrophic lateral sclerosis." Acta Neurologica Scandinavica 124, no. 5 (2011): 360. http://dx.doi.org/10.1111/j.1600-0404.2011.01534.x.

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Belvederi Murri, Martino, Flaminia Fanelli, Uberto Pagotto, et al. "Neuroactive Steroids in First-Episode Psychosis: A Role for Progesterone?" Schizophrenia Research and Treatment 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/1942828.

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Neuroactive steroids may play a role in the pathophysiology of psychotic disorders, but few studies examined this issue. We compared serum levels of cortisol, testosterone, dehydroepiandrosterone, and progesterone between a representative sample of first-episode psychosis (FEP) patients and age- and gender-matched healthy subjects. Furthermore, we analyzed the associations between neuroactive steroids levels and the severity of psychotic symptom dimensions. Male patients had lower levels of progesterone than controls (p=0.03). Progesterone levels were inversely associated with the severity of

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Levin, Gabriel, and Amihai Rottenstreich. "Vaginal progesterone treatment and circulating progesterone levels-an association yet to be determined." Acta Obstetricia et Gynecologica Scandinavica 98, no. 3 (2018): 397. http://dx.doi.org/10.1111/aogs.13472.

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Chandrasekhar, Yallampalli, and David T. Armstrong. "Effects of the antiandrogen hydroxyflutamide on progesterone secretion by preovulatory rat follicles in vivo and in vitro." Canadian Journal of Physiology and Pharmacology 69, no. 9 (1991): 1288–93. http://dx.doi.org/10.1139/y91-189.

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Serum and ovarian progesterone levels and in vitro production of progesterone by preovulatory follicles were measured on proestrus in pregnant mare's serum gonadotropin (PMSG) primed immature rats in which the luteinizing hormone (LH) surge and ovulation were blocked by administration of the antiandrogen hydroxyflutamide. Serum progesterone levels observed at 12:00 on proestrus were significantly elevated, twofold above those observed in vehicle-treated controls, by in vivo administration of 5 mg hydroxyflutamide 4 h earlier. In control rats, proestrous progesterone did not increase until 16:0

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Roesch, D. M., and M. Keller-Wood. "Progesterone rapidly reduces arterial pressure in ewes." American Journal of Physiology-Heart and Circulatory Physiology 272, no. 1 (1997): H386—H391. http://dx.doi.org/10.1152/ajpheart.1997.272.1.h386.

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Chronic progesterone treatment decreases mean arterial pressure (MAP) and expands plasma volume. Evidence now suggests that progesterone metabolites have rapid nongenomic actions on the baroreflex. This experiment tests for a rapid effect of progesterone on MAP,Na+, arginine vasopressin, and baroreflex sensitivity. Ewes were studied during 2-h infusions of vehicle or progesterone at 3 and 6 micrograms.kg-1.min-1. Infusion of progesterone at 3 micrograms.kg-1.min-1 resulted in progesterone levels characteristic of ovine pregnancy and significantly reduced MAP by the 17th minute, suggesting a no

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Harlow, Henry J., Thomas D. I. Beck, Lisa M. Walters, and Shelley S. Greenhouse. "Seasonal serum glucose, progesterone, and Cortisol levels of black bears (Ursus americanus)." Canadian Journal of Zoology 68, no. 1 (1990): 183–87. http://dx.doi.org/10.1139/z90-025.

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Sixty-two black bears were captured at different seasons during the years 1983–1987. Bears were anesthetized in their dens during the winter and parts of the fall and spring, while bears captured during the summer were snared prior to anesthesia. Radioimmunoassays for both Cortisol and progesterone were validated on black bear serum. An improved, rapid progesterone radioimmunoassay for black bear serum is reported. Serum glucose demonstrated a tendency for reduction during spring. Serum progesterone levels did not demonstrate seasonal differences and were significantly higher in females only d

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Bailey, K. J. "Diurnal progesterone rhythms in the female mouse." Journal of Endocrinology 112, no. 1 (1987): 15–21. http://dx.doi.org/10.1677/joe.0.1120015.

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ABSTRACT The patterns of peripheral progesterone concentrations were investigated in a number of murine models on a 13 h light: 11 h darkness lighting regime. The pattern in the intact mouse at dioestrus was compared with that in the ovariectomized mouse. A diurnal pattern was recorded in both, maxima occurring around the end of the light period; no conspicuous nadir was recorded, levels of progesterone remaining relatively constant over a 14-h period. Adrenalectomized mice displayed no such rhythm, indicating that the adrenal is responsible for any diurnal rhythm in peripheral plasma progeste

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Thipasary, Yanne, Jusuf Sulaeman Effendi, and Anita Deborah Anwar. "The Role of Natural Progesterone Administration on the Levels of Progesterone-induced Blocking Factor, Interleukin-10 and the Prolongation of Gestational Length in Impending Preterm Delivery." Journal of South Asian Federation of Obstetrics and Gynaecology 7, no. 3 (2015): 118–25. http://dx.doi.org/10.5005/jp-journals-10006-1340.

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ABSTRACT Progesterone plays an important role in maintaining pregnancy. The success of pregnancy depends on the balance of immune response between the mother and the fetus. Progesterone regulates the immunological response through progesteroneinduced blocking factor (PIBF) which is synthesized by lymphocytes. Progesterone-induced blocking factor inhibits the production of arachidonic acid, reduced NK cell activity, and modulates the cytokine balance by increasing interleukin-10 (IL-10) level that is produced by Th2. This study aims to determine the roles of natural progesterone administration

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Al Riyami, Bashair, Marah El-Tahir, Sultan Al Maskari, Eugene H. Johnson, and Jumana Saleh. "Acute Effects of Exogenous Hormone Administration on Postprandial Acylation Stimulating Protein Levels in Ovariectomized Rats after a Fat Load." Journal of Nutrition and Metabolism 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/510916.

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Background. ASP, a potent lipogenic factor, was linked to female fat metabolism in association studies.Aim. To investigate acute effects of sex hormone treatment on postprandial ASP levelsin vivo.Methods. 24 female rats were randomly divided into 4 groups including controls. The rats were ovariectomized and injected with progesterone, estrogen, or testosterone. An hour later, olive oil was administered orally. Plasma ASP and triglycerides were measured at several postprandial time points. Area under the curve (TG-AUC) represented TG clearance.Results. Only the progesterone treated group had a

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Yen, Lin, Lin, Liu, Long, and Ko. "Early- and Late-Luteal-Phase Estrogen and Progesterone Levels of Women with Premenstrual Dysphoric Disorder." International Journal of Environmental Research and Public Health 16, no. 22 (2019): 4352. http://dx.doi.org/10.3390/ijerph16224352.

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: Objective/introduction: The dynamics of ovarian hormone fluctuations during the luteal phase of the menstruation cycle were previously suggested to contribute to the development of premenstrual dysphoric disorder (PMDD) symptoms, but adequate empirical evidence has not been obtained from hormone concentration studies. We prospectively evaluated estrogen and progesterone levels in the early luteal (EL) and late luteal (LL) phases in women with PMDD and the association of these levels with PMDD symptom severity. Methods: 63 women with PMDD and 53 controls without such severe symptoms were eval

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Flores-Ramos, M., and I. Méndez Ramírez. "FC11-05 - Hormonal profile in depressed and non-depressed perimenopausal women." European Psychiatry 26, S2 (2011): 1874. http://dx.doi.org/10.1016/s0924-9338(11)73578-7.

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ObjectiveTo determine if serum levels of Follicle Stimulating Hormone, Luteinizing Hormone, estradiol, progesterone, Free Testosterone and Total Testosterone differ between perimenopausal women with first depressive episode, recurrent depression and without depression.MethodsDemographic and clinical characteristics were evaluated in 63 perimenopausal women with first depressive episode (N = 20), recurrent depression (N = 23) or non-depressed (N = 20). Hormonal measurements were evaluated at follicular and luteal menstrual phases and mid-cycle, around one menstrual cycle.ResultsWhen compared de

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Okulicz, W. C. "Temporal effects of progesterone inhibition of occupied nuclear oestrogen receptor retention in the rat uterus." Journal of Endocrinology 121, no. 1 (1989): 101–7. http://dx.doi.org/10.1677/joe.0.1210101.

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ABSTRACT Previous studies have shown that progesterone rapidly inhibits retention of uterine nuclear oestrogen receptor in several mammalian species. This effect of progesterone may constitute a general mechanism by which progesterone modulates oestrogen action. The objective of the present study was to examine the temporal pattern of progesterone inhibition of retention of occupied nuclear oestrogen receptors in the rat uterus at various sustained serum concentrations of progesterone. Silicone elastomer implants (1 cm) packed with crystalline oestrogen were placed s.c. in the flank region of

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González-Foruria, I., I. Rodríguez, F. Martínez, et al. "Clinically significant intra-day variability of serum progesterone levels during the final day of oocyte maturation: a prospective study with repeated measurements." Human Reproduction 34, no. 8 (2019): 1551–58. http://dx.doi.org/10.1093/humrep/dez091.

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Abstract STUDY QUESTION Is there significant variability in progesterone levels during the final day of oocyte maturation in women undergoing ovarian stimulation? SUMMARY ANSWER Progesterone levels drop from the basal level up to 44% during the final day of oocyte maturation in women undergoing ovarian stimulation. WHAT IS KNOWN ALREADY It has been suggested that elevated progesterone levels on the final day of ovarian stimulation may be related to poorer outcomes in in vitro fertilization fresh cycles due to a negative impact on the endometrium. However, despite conflicting results regarding

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Sadiq, Mas’ud E., Aminu L. Abubakar, Almustapha Lawal, Alkassim H. Ahmad, and Nafisa Sada. "Preterm deliveries and progesterone levels in pregnant women attending antenatal care in a health care facility in Sokoto state, Nigeria: a preliminary study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 7 (2020): 2969. http://dx.doi.org/10.18203/2320-1770.ijrcog20202742.

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Background: Progesterone related complication during pregnancy is currently being viewed as one of the underlying causes of miscarriages and preterm deliveries. Progesterone assay is often neglected during routine screening in antenatal clinics (ANC) in primary health care centres in Nigeria. This study was designed to monitor 40 volunteer expecting mothers between the ages 18-35 years with a history of child birth and to evaluate serum progesterone levels accordingly for pregnancy in second and third trimesters.Methods: Volunteers were categorized according to their age and stage of pregnancy

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Nishikawa, S., R. C. Moore, N. Nonomura, and T. Oka. "Progesterone and EGF inhibit mouse mammary gland prolactin receptor and beta-casein gene expression." American Journal of Physiology-Cell Physiology 267, no. 5 (1994): C1467—C1472. http://dx.doi.org/10.1152/ajpcell.1994.267.5.c1467.

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Regulation of mouse mammary gland long-form prolactin receptor (PRL-RL) mRNA levels by progesterone and epidermal growth factor (EGF) and the relationship between PRL-RL and beta-casein gene expression were examined in vivo and in vitro. PRL-RL and beta-casein mRNA levels increased approximately 6- and 15-fold from the pregnant to the lactating period, respectively, when normalized to the level of beta-actin mRNA. Ovariectomy of pregnant mice rapidly reduced the serum concentration of progesterone and increased the level of PRL-RL and beta-casein mRNAs approximately three- and fourfold compare

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Hlavaty, Juraj, Reinhard Ertl, Ingrid Miller, and Cordula Gabriel. "Expression of Progesterone Receptor Membrane Component 1 (PGRMC1), Progestin and AdipoQ Receptor 7 (PAQPR7), and Plasminogen Activator Inhibitor 1 RNA-Binding Protein (PAIRBP1) in Glioma SpheroidsIn Vitro." BioMed Research International 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/8065830.

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Objective.Some effects of progesterone on glioma cells can be explained through the slow, genomic mediated responsevianuclear receptors; the other effects suggest potential role of a fast, nongenomic action mediated by membrane-associated progesterone receptors.Methods.The effects of progesterone treatment on the expression levels of progesterone receptor membrane component 1 (PGRMC1), plasminogen activator inhibitor 1 RNA-binding protein (PAIRBP1), and progestin and adipoQ receptor 7 (PAQR7) on both mRNA and protein levels were investigated in spheroids derived from human glioma cell lines U-

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Zargar-Shoshtari, Sara, Hannaneh Wahhabaghei, Abdolrasoul Mehrsai, Jingyuan Wen та Raid Alany. "Transdermal Delivery of Bioidentical Progesterone with a Steroid 5α-Reductase Inhibitor (Dutasteride): a Pilot Study". Journal of Pharmacy & Pharmaceutical Sciences 13, № 4 (2011): 626. http://dx.doi.org/10.18433/j3rw2h.

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Purpose: Bioavailability of transdermal progesterone is low and variable. This may be attributed to transdermal metabolism by the 5α-reductase enzymes or the direct transport to the saliva. The objective of the current study was to evaluate the effect of enzyme inhibition on the bioavailability of transdermal progesterone. Serum and salivary progesterone levels were evaluated to gain a better insight into the mechanism progesterone transport across the skin. Method: Twenty postmenopausal women with a Follicle Stimulating Hormone > 40iu/L were recruited to take part in the study. The subject

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Bogdanova, S. "New data on progesterone levels and the limits of the fertile period in dogs." Genetics and breeding of animals, no. 2 (August 26, 2022): 132–35. http://dx.doi.org/10.31043/2410-2733-2022-2-132-135.

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Purpose: to clarify the possibility of pregnancy in dogs with blood progesterone levels above 20 ng/ml.Materials and methods. The study was conducted in the period from January 2018 to May 2022. The study involved 25 females of various breeds aged from 1.5 to 8 years. The progesterone level of peripheral blood was analyzed, taken into vacuum tubes using a butterfly needle with a size from 20G to 23G, the size of the needle section was selected depending on the thickness of the anterior subcutaneous vein of the forearm, from which samples were taken. Blood sampling for progesterone is performed

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