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Journal articles on the topic 'Progesterone'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lubis, Pika Novriani. "Efektivitas Progesteron Oral dan Vagina pada Tata Laksana Abortus Imminens." Cermin Dunia Kedokteran 50, no. 6 (2023): 339–41. http://dx.doi.org/10.55175/cdk.v50i6.922.

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Abortus imminens adalah perdarahan yang terjadi sebelum usia kehamilan 20 minggu, tanpa keluarnya janin. Selama kehamilan, progesteron berperan dalam proses implantasi janin ke dalam rahim. Beberapa penelitian menunjukkan bahwa progesteron bermanfaat dalam penanganan abortus imminens, baik dalam bentuk oral maupun supositoria. Sediaan oral terbukti lebih efektif dibandingkan progesteron vaginal. Threatened miscarriage or imminent abortion is vaginal bleeding that happened before a 20-week gestation without fetus expulsion. During pregnancy, progesterone plays a role in the process of imp

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Szrok-Jurga, Sylwia, Jacek Turyn, Julian Swierczynski, Wiktoria Stelmanska, Malgorzata Presler, and Ewa Stelmanska. "Gender-Dependent Effect of Progesterone on the Expression of Metallothionein Genes in Rat Inguinal Adipose Tissue." International Journal of Molecular Sciences 26, no. 9 (2025): 4066. https://doi.org/10.3390/ijms26094066.

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Metallothioneins (MTs) are low-molecular-weight metal-binding proteins potentially involved in the detoxification of heavy metals, protection against oxidative stress, and other biological processes. This study examined progesterone’s influence on Mt gene expression in rat adipose tissue. Wistar rats (females and males) received 100 mg of progesterone per rat. MT mRNA and protein levels were quantified by real-time PCR and Western blotting methods. Using radioimmunoassay, the serum progesterone level was measured. In this study, progesterone administration to female rats led to a 2.5-fold incr

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Setiawan, Angga, Elis Dihansih, and Desy Zamanti. "PENGGUNAAN PREPARAT PROGESTERON DAN HORMON GnRH DALAM PENENTUAN ESTRUS PADA PROGRAM SUPEROVULASI SAPI LIMOSIN." JURNAL PERTANIAN 8, no. 1 (2017): 7. http://dx.doi.org/10.30997/jp.v8i1.631.

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Program superovulasi dapat dilakukan dengan Perlakuan hormonal, hormon yang sering digunakan antara lain: Preparat Progesteron dan hormon GnRH sebagai penentu estrus dalam program superovulasi. Penelitian ini bertujuan untuk menguji pengaruh implan preparat progesteron dan penggunaan hormon GnRH terhadap respon superovulasi. Penelitian ini menggunakan 10 ekor sapi Limosin yang memiliki umur 3 – 7 tahun, genetik unggul, siklus estrus normal, fertilitas tinggi, dan bebas dari penyakit reproduksi menular. Semua sapi telah dilakukan seleksi dengan cara palpasi rektal untuk menentukan status ovariu

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Panjaitan, Budianto, Citra Chyntia Helwana, Nellita Meutia, et al. "Hubungan Kadar Progesteron pada Fase Awal Luteal dengan Kematian Embrio pada Sapi Aceh." Jurnal Agripet 19, no. 2 (2019): 107–12. http://dx.doi.org/10.17969/agripet.v19i2.14881.

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ABSTRAK. Progesteron merupakan hormon yang berperan penting dalam proses pemeliharaan kebuntingan dan dihasilkan oleh corpus luteum. Penelitian ini bertujuan mengetahui hubungan antara kadar hormon progesteron pada fase awal luteal dengan kematian embrio pada sapi Aceh. Dalam penelitian ini digunakan empat ekor sapi betina dewasa berumur 3-5 tahun, bobot badan 150-250 kg, sehat secara klinis, dan memiliki reproduksi normal. Sapi disinkronisasi menggunakan 5 ml prostaglandin F2 alfa (PGF2α) dengan pola penyuntikan ganda berinterval 11 hari. Koleksi sampel darah untuk pengukuran konsentrasi prog

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DeMayo, Francesco J., and John P. Lydon. "90 YEARS OF PROGESTERONE: New insights into progesterone receptor signaling in the endometrium required for embryo implantation." Journal of Molecular Endocrinology 65, no. 1 (2020): T1—T14. http://dx.doi.org/10.1530/jme-19-0212.

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Progesterone’s ability to maintain pregnancy in eutherian mammals highlighted this steroid as the ‘hormone of pregnancy’. It was the unique ‘pro-gestational’ bioactivity of progesterone that enabled eventual purification of this ovarian steroid to crystalline form by Willard Myron Allen in the early 1930s. While a functional connection between normal progesterone responses (’progestational proliferation’) of the uterus with the maintenance of pregnancy was quickly appreciated, an understanding of progesterone’s involvement in the early stages of pregnancy establishment was comparatively less w

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Chaudhari, Shilpa, Aparajita Mishra, Kishor Hol, and Shraddha Shastri. "Compare safety and efficacy of intramuscular progesterone versus vaginal progesterone in prevention of preterm labour." Indian Journal of Obstetrics and Gynecology Research 8, no. 4 (2021): 541–47. http://dx.doi.org/10.18231/j.ijogr.2021.111.

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Currently preterm labour is one of the most challenging problem faced by both obstetricians and perinatologists, this episode in the course of woman’s pregnancy takes a heavy tool for perinatal mortality which accounts for approximately 50-75%. The incidence of preterm labour is estimated to be 5-10% of all pregnancies. It was a prospective randomize control study. All the cases with inclusion and exclusion criteria were selected during the study period. The subjects were randomized into two groups with group A received vaginal micronized progesteron and group B intramuscular 17a hydroxyproges

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Merkis, Cecilia I., and Adriana B. Vivas. "Actividad sérica del Factor Precoz de Preñez (EPF) durante la gestación en porcinos." Revista Colombiana de Ciencias Pecuarias 15, no. 1 (2016): 63–67. http://dx.doi.org/10.17533/udea.rccp.323789.

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Resumen Para lograr una preñez exitosa es necesario un reconocimiento inmunológico entre la madre y el feto. Tal reconocimiento se realizaría a través de señales como el Factor precoz de preñez (EPF) y de hormonas como la progesterona, que se sintetizan muy tempranamente y poseen actividad inmunosupresora. En este trabajo, se estudió el comportamiento de ambas sustancias durante toda la gestación en porcinos. Se investigó en el suero de 5 cerdas, la actividad de EPF y la concentración de progesterona en estro y en los días 3, 7, 14, 21, 28, 45, 75, 90 y 110 post-servicio. La actividad del EPF

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Widi Nugroho, Setyo, Harris Istianggoro, Fabianto Santoso, David Tandian, Renindra Ananda Aman, and Eka Susanto. "Characteristics and Correlation Between Progesterone Receptors and The Use of Hormonal Contraceptive in Women with Meningioma in dr. Cipto Mangunkusumo National General Hospital." eJournal Kedokteran Indonesia 10, no. 2 (2022): 101–6. http://dx.doi.org/10.23886/ejki.10.161.101-6.

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Meningiomas are the most common primary, intracranial and extra axial tumours, estimated for 30% of all intracranial tumors. The use of hormonal contraceptive is one of the risk factors for meningioma, but the studies still have controversial results. The purpose of this study is to describe the characteristics and to correlate between progesterone receptor and the use of hormonal contraceptive in women diagnosed with brain tumor meningioma. This is a cross-sectional study which collect data in dr. Cipto Mangunkusumo National General Hospital in the year 2017-2018. Patient data collection was

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9

Jerat, Sandra, and Susan Kaufman. "Effect of pregnancy and steroid hormones on plasma adrenomedullin levels in the rat." Canadian Journal of Physiology and Pharmacology 76, no. 4 (1998): 463–66. http://dx.doi.org/10.1139/y98-113.

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Pregnancy is characterized by volumeexpansion and vasodilation. We investigated whether thehypotensive peptide adrenomedullin (ADM) might be a significantfactor in the cardiovascular adaptation to pregnancy. Rats wereprepared with indwelling cannulae. Plasma ADM levels weremeasured by RIA before mating, at 7, 14, and 21 days ofpregnancy, and at 7 days postpartum. We also investigated theeffects on plasma ADM levels of administering estrogen,progesterone, and the metabolite of progesterone3-OH-5-pregnan-20-one(3-OH-DHP); this last steroid has been implicated inaltering reflex control of blood p

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10

Hornung, Rebecca S., Namrata GR Raut, Daisy J. Cantu, Lauren M. Lockhart, and Dayna L. Averitt. "Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone." Molecular Pain 18 (January 2022): 174480692110692. http://dx.doi.org/10.1177/17448069211069255.

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Orofacial pain disorders are predominately experienced by women. Progesterone, a major ovarian hormone, is neuroprotective and antinociceptive. We recently reported that progesterone attenuates estrogen-exacerbated orofacial pain behaviors, yet it remains unclear what anatomical substrate underlies progesterone’s activity in the trigeminal system. Progesterone has been reported to exert protective effects through actions at intracellular progesterone receptors (iPR), membrane-progesterone receptors (mPR), or sigma 1 receptors (Sig-1R). Of these, the iPR and Sig-1R have been reported to have a

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11

Dosiou, C., A. E. Hamilton, Y. Pang, et al. "Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone." Journal of Endocrinology 196, no. 1 (2007): 67–77. http://dx.doi.org/10.1677/joe-07-0317.

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Although there is significant evidence for progesterone's role as an immunomodulator, nuclear progesterone receptors have not been consistently identified in immune cells. Recently, three new putative membrane progesterone receptors (mPRs), mPRα, mPRβ, and mPRγ have been described. The objective of this study was to examine whether mPRs are expressed in peripheral blood leukocytes (PBLs) in women of reproductive age, and to further characterize them in T lymphocytes and immortalized T cells (Jurkat cells). Transcripts for mPRα and mPRβ but not mPRγ, were detected by RT-PCR in PBLs, T lymphocyt

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12

&NA;. "Progesterone see Estrogen/progesterone." Reactions Weekly &NA;, no. 375 (1991): 12. http://dx.doi.org/10.2165/00128415-199103750-00071.

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&NA;. "Progesterone see Estrogen/progesterone." Reactions Weekly &NA;, no. 287 (1990): 7. http://dx.doi.org/10.2165/00128415-199002870-00025.

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14

Sadeghi, Homayoun, та Hugh S. Taylor. "HOXA10 regulates endometrial GABAA π receptor expression and membrane translocation". American Journal of Physiology-Endocrinology and Metabolism 298, № 4 (2010): E889—E893. http://dx.doi.org/10.1152/ajpendo.00577.2009.

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Expression of the GABAA π receptor has been described previously in the human endometrium in both luminal epithelium and stroma. Its expression is increased during decidualization in rodents and in the implantation window of human endometrium. Here we localized GABA π subunit receptor protein in human endometrium and identified regulators of gene expression and activation. GABAA π was localized to the cell surface, and expression increased during the window of embryo implantation in human endometrium. The well-differentiated human endometrial adenocarcinoma cell line Ishikawa was treated with

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15

Peluso, John J., and Anna Pappalardo. "Progesterone and cell–cell adhesion interact to regulate rat granulosa cell apoptosis." Biochemistry and Cell Biology 72, no. 11-12 (1994): 547–51. http://dx.doi.org/10.1139/o94-073.

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Ovarian follicles are composed of both small and large granulosa cells, but only the large granulosa cells undergo apoptosis within 24 h of culture in serum-free medium. The present study was designed to assess the relationship between cell–cell contact, progesterone treatment, and granulosa cell apoptosis. For this study, individual large granulosa cells were isolated from immature rat ovaries after sequential incubation with EGTA and EGTA–sucrose solutions. Granulosa cells were then cultured for 24 h in RPMI-1640 (control) supplemented with progesterone and (or) the progesterone antagonist R

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16

Fernandez-Valdivia, Rodrigo, Atish Mukherjee, Chad J. Creighton, et al. "Transcriptional Response of the Murine Mammary Gland to Acute Progesterone Exposure." Endocrinology 149, no. 12 (2008): 6236–50. http://dx.doi.org/10.1210/en.2008-0768.

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Our mechanistic understanding of progesterone’s involvement in murine mammary morphogenesis and tumorigenesis is dependent on defining effector pathways responsible for transducing the progesterone signal into a morphogenetic response. Toward this goal, microarray methods were applied to the murine mammary gland to identify novel downstream gene targets of progesterone. Consistent with a tissue undergoing epithelial expansion, mining of the progesterone-responsive transcriptome revealed the up-regulation of functional gene classes involved in epithelial proliferation and survival. Reassuringly

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17

Mlaco, N., A. Katica, B. Cengic, and V. Sakic. "Results of applying gonadorelin Fertagyl on the progesterone concentrations in the blood serum and cow conception." Biotehnologija u stocarstvu 29, no. 1 (2013): 19–28. http://dx.doi.org/10.2298/bah1301019m.

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Considering there are different and inconsistent results of the wider use of gonadotropin-releasing hormone or its analogs in cattle breeding and due to scarce research studies in the field of individual breeding, we decided to explore the influence of gonadorelin Fertagyl on the results of the blood serum progesterone levels and conception of cows in veterinary field practice. Examination of the progesterone levels involved 14 (fourteen) cows treated with gonadorelin (GnRH), Fertagyl, manufactured by Intervet, according to the manufacturer?s instructions dose of 2,5ml (250 micrograms), within

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18

Duarsa, Ni Made Meta Satya Buda, Izza Mufida, Daffa Aulia Faza Adhima, and Muhammad Rizkinov Jumsa. "THE ROLE OF PROGESTERONE AND BETA-HUMAN CHORIONIC GONADOTROPIN IN ECTOPIC PREGNANCY." Jurnal Ilmu Kedokteran dan Kesehatan 11, no. 1 (2024): 083–87. http://dx.doi.org/10.33024/jikk.v11i1.12960.

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Abstrak: Peran Progesterone dan Beta-Human Chorionic Gonadotropin dalam Kehamilan Ektopik. Angka kematian ibu (AKI) telah umum diterima sebagai salah satu indikator tingkat kesehatan suatu negara. Kehamilan ektopik (KE) adalah komplikasi kehamilan dengan morbiditas dan mortalitas atau tingkat kematian yang tinggi jika tidak dideteksi dan ditangani dengan segera. Pengukuran serum progesteron dan beta-human chorionic gonadotropin (β-hCG) memiliki potensi untuk mendeteksi dini kehamilan ektopik. Artikel ini bertujuan untuk membahas peran progesterone dan β-hCG dalam kehamilan ektopik. Metode yang

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Larsen, Bryan, and Joseph Hwang. "Progesterone Interactions with the Cervix: Translational Implications for Term and Preterm Birth." Infectious Diseases in Obstetrics and Gynecology 2011 (2011): 1–13. http://dx.doi.org/10.1155/2011/353297.

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The uterine cervix plays a vital role in maintaining pregnancy and an equally important role in allowing parturition to occur. Progesterone, either endogenously produced or supplied exogenously, supports the function of the cervix in sustaining intrauterine pregnancy, and the withdrawal of progesterone, either through natural processes or pharmacologic intervention, leads to delivery which underscores the importance of the progesterone's biological activities manifest in normal gestation and pregnancy that ends prematurely. Research crossing many scientific disciplines has demonstrated that pr

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20

Zhang, Qi, and Wen Xuan Wu. "Separate and synergistic effect of progesterone and estradiol on induction of annexin 2 and its interaction protein p11 in pregnant sheep myometrium." Journal of Molecular Endocrinology 38, no. 4 (2007): 441–54. http://dx.doi.org/10.1677/jme.1.02143.

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To search for myometrial candidate genes regulated by progesterone, we isolated annexin 2 cDNA by subtractive hybridization and cloning. We also examined the effect of estradiol and/or progesterone, individually or combined, on expressions of annexin 2 and its ligand protein, p11 in pregnant sheep intrauterine tissues. Annexin 2 is a Ca2+-dependent phospholipid-binding protein which interacts with p11 to form a bivalent heterotetramer. The heterotetramer was indicated in the production of prostaglandins through the regulation of cytosolic phospholipase A2 (cPLA2) and arachidonic acid release.

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MESIANO, SAM, and TONI WELSH. "PROGESTERONE AND THE CONTROL OF HUMAN PREGNANCY AND PARTURITION." Fetal and Maternal Medicine Review 20, no. 2 (2009): 97–118. http://dx.doi.org/10.1017/s096553950900240x.

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Almost 80 years ago George Corner and colleagues provided the first evidence that progesterone maintains pregnancy and that it does so, at least in part, by promoting myometrial relaxation. In the 1950s, Arpad Csapo proposed the “progesterone block hypothesis”, which posits that progesterone maintains pregnancy by promoting myometrial relaxation and that its withdrawal initiates a cascade of hormonal interactions that transforms the myometrium to a highly contractile state leading to the onset of labour. Csapo later proposed that contractility of the pregnant myometrium is determined by the ba

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DS, Bhosale, and Kalshetti MS. "Amplification of Aqueous Solubility of Progesterone Using Melt-Granulation Technique." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 26–32. http://dx.doi.org/10.25258/ijddt.14.1.05.

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The objective of the present research was to enhance the rate of dissolution of progesterone by boosting the hormone’s solubility in water. This research determines whether or not employing melt granulation techniques with various polymers may improve the degree to which progesterone is soluble. When looking into the interactions between drug carriers and other substances, researchers turned to techniques such as X-ray diffraction (XRD), differential scanning calorimetry (DSC), and Fourier transform infrared (FTIR). PEG 6000 (1:1.5) demonstrated the highest solubility, followed by PEG 6000 (1:

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Chatterjee, Ankita, and Nida Afreen. "Soil fungi, Aspergillus niger NAAC, as environmental pollution clean-up agent against Progesterone: Remediation strategy and preparation of Bioformulation." Applied Environmental Biotechnology 7, no. 2 (2022): 15–20. http://dx.doi.org/10.26789/aeb.2022.02.003.

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The presence of hormones, drugs and chemicals in the environment are disrupting the ecosystem. The existence of chemicals in the environment is a threat to the ecosystem as they have dangerous effects on animals, plants and microbes. Progesterones are steroid hormones used for human contraceptives and therapeutic purposes as well as promoting animal growth. The cases of consumption of progesterone for medical purposes are much higher than estrogens, however, much studies related to estrogens have been conducted thereby neglecting the effects of progesterone. This invention focuses on removal o

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1378 (2011): 29. http://dx.doi.org/10.2165/00128415-201113780-00106.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1381 (2011): 25. http://dx.doi.org/10.2165/00128415-201113810-00091.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1382 (2011): 29. http://dx.doi.org/10.2165/00128415-201113820-00107.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1394 (2012): 35. http://dx.doi.org/10.2165/00128415-201213940-00130.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1161 (2007): 21. http://dx.doi.org/10.2165/00128415-200711610-00066.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1186 (2008): 32. http://dx.doi.org/10.2165/00128415-200811860-00102.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1188 (2008): 20. http://dx.doi.org/10.2165/00128415-200811880-00065.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1189 (2008): 29. http://dx.doi.org/10.2165/00128415-200811890-00092.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1159 (2007): 24. http://dx.doi.org/10.2165/00128415-200711590-00073.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1359 (2011): 31. http://dx.doi.org/10.2165/00128415-201113590-00121.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 590 (1996): 13. http://dx.doi.org/10.2165/00128415-199605900-00043.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1201 (2008): 25. http://dx.doi.org/10.2165/00128415-200812010-00071.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1224 (2008): 24. http://dx.doi.org/10.2165/00128415-200812240-00072.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1089 (2006): 22. http://dx.doi.org/10.2165/00128415-200610890-00072.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1102 (2006): 13. http://dx.doi.org/10.2165/00128415-200611020-00039.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 923 (2002): 10–11. http://dx.doi.org/10.2165/00128415-200209230-00035.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1258 (2009): 26. http://dx.doi.org/10.2165/00128415-200912580-00088.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1268 (2009): 25. http://dx.doi.org/10.2165/00128415-200912680-00080.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1332 (2010): 35–36. http://dx.doi.org/10.2165/00128415-201013320-00123.

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&NA;. "Progesterone." Reactions Weekly &NA;, no. 1352 (2011): 32–33. http://dx.doi.org/10.2165/00128415-201113520-00121.

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MAGGIO, LINDSAY, and DWIGHT J. ROUSE. "Progesterone." Clinical Obstetrics and Gynecology 57, no. 3 (2014): 547–56. http://dx.doi.org/10.1097/grf.0000000000000039.

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Pickar, James H. "Progesterone." Climacteric 21, no. 4 (2018): 305. http://dx.doi.org/10.1080/13697137.2018.1462910.

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Suparman, Erna, and Eddy Suparman. "PEMBERIAN PROGESTERON PADA KEGUGURAN BERULANG." JURNAL BIOMEDIK (JBM) 5, no. 2 (2013). http://dx.doi.org/10.35790/jbm.5.2.2013.2588.

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Abstract: Recurrent pregnancy loss (RPL) occurs in 0.5-1% of partners. The pathophysiology of this RPL is complex. The causes include anatomical, genetic and molecular abnormalities, endocrine disorders, thrombophilia, and the anti-phospholipid syndrome, meanwhile in 50% of cases no cause can be identified. Progesterone is needed to create a suitable environment for the implantation. Low progesterone level during early pregnancy may reflect corpus luteum defects or abnormal products of conception. Besides that, low progesterone is a sign of a coming miscarriage; an administration of progestero

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Ozcan, P., Ç. Çetin, B. Ökten, et al. "P-579 The effect of serum progesterone level on ET Day and the efficacy of rescue progesterone treatment on ongoing pregnancy rates with artificial FET cycles." Human Reproduction 37, Supplement_1 (2022). http://dx.doi.org/10.1093/humrep/deac107.534.

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Abstract Study question To evaluate serum progesteron level on ET day during FET cycles with a vaginal progesterone tablet plus weekly twice IM progesteron; to determine the efficacy of resque sc progesteron treatment Summary answer Resque daily sc progesterone treatment can improve PRs. The measurement of progesterone on ET day may create a chance to resque treatment on ET day. What is known already Successful implantation requires a suitable decidualized endometrium combined with a good quality embryo. The secretory phase of endometrium induced by progesterone is one of the most crucial step

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Rajuddin, Rajuddin, Fitra Rizia, and Sarah I. Nainggolan. "Role of C-Reactive Protein, Erythrocyte Sedimentation Rate, Progesterone and Estradiol Hormone Levels in First Trimester Threatened Abortion." Indonesian Journal of Obstetrics and Gynecology, January 22, 2021, 42–48. http://dx.doi.org/10.32771/inajog.v9i1.1386.

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Objective: To assess correlation of High sensitivity C-Reactive Protein (Hs-CRP), erythrocyte sedimentation rate (ESR), progesterone and estradiol levels in the first trimester threatened abortion incidence in Dr. Zainoel Abidin Hospital, Banda Aceh.Methods: Case control design used in this study divided threatened abortion into a case group and normal pregnancy into a control group with a total of 20 subjects for each group. This research was conducted in the Emergency Room and Obstetric Ward of Dr. Zainoel Abidin hospital Banda Aceh in 2019. Eta correlation test was conducted to find out the

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Berg, Malia, and Matthew Dean. "Membrane progesterone receptors mediate progesterone-stimulated glycogenolysis in the bovine uterine epithelium." Reproduction, September 2024. http://dx.doi.org/10.1530/rep-24-0174.

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In livestock, the amount of glucose needed by the endometrium and embryo increases during early pregnancy. Yet, how glucose concentrations in the endometrium are regulated remains unclear. The bovine uterine epithelium can store glucose as glycogen, and glycogen content decreases in the luteal phase. Our objective was to elucidate the role of progesterone in glycogen breakdown in immortalized bovine uterine epithelial (BUTE) cells. After 48 hours of treatment, progesterone decreased glycogen abundance in BUTE cells (P<0.001) but did not alter glycogen phosphorylase levels. RU486, a nuclear

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Demir Çendek, Büşra, Gulsah Dagdeviren, Şevki Çelen, and Ali Çağlar. "Assessing the relationship between intrahepatic cholestasis of pregnancy and exogenous progesterone intake." Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, May 20, 2024. http://dx.doi.org/10.38136/jgon.1410939.

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Abstract:

Abstract Aim: Progesterone metabolites are known to be elevated in the serum of patients with intrahepatic cholestasis of pregnancy (ICP), and exogenous progesterone supplementation in early pregnancy may cause an increase in progesterone metabolites. The aim of this study is to investigate the relationship between ICP and exogenous progesterone intake. Materials and Methods: This study is a retrospective case-control study conducted between January 2015 and November 2023. The groups liver function tests, total bile acids, maternal age, body mass index, parity, history of cholestasis, history

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