Relevant bibliographies by topics / Prolinamid

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Prolinamid'

Author: Grafiati
Published: 24 April 2022
Last updated: 30 July 2025

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Journal articles on the topic "Prolinamid"

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Maciá, María, Raúl Porcar, Vicente Martí-Centelles, Eduardo García-Verdugo, Maria Isabel Burguete, and Santiago V. Luis. "Rational Design of Simple Organocatalysts for the HSiCl3 Enantioselective Reduction of (E)-N-(1-Phenylethylidene)aniline." Molecules 26, no. 22 (2021): 6963. http://dx.doi.org/10.3390/molecules26226963.

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Prolinamides are well-known organocatalysts for the HSiCl3 reduction of imines; however, custom design of catalysts is based on trial-and-error experiments. In this work, we have used a combination of computational calculations and experimental work, including kinetic analyses, to properly understand this process and to design optimized catalysts for the benchmark (E)-N-(1-phenylethylidene)aniline. The best results have been obtained with the amide derived from 4-methoxyaniline and the N-pivaloyl protected proline, for which the catalyzed process is almost 600 times faster than the uncatalyzed
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Hoffm�ller, Winfried, Kurt Polborn, J�rg Knizek, Heinrich N�th, and Wolfgang Beck. "Metallkomplexe mit biologisch wichtigen Liganden. XCV. ?5- Pentamethylcyclopentadienyl-Rhodium-, -Iridium-, (?6-Benzol)-Ruthenium- und Phosphan-Palladium-Komplexe von Prolinmethylester und Prolinamid." Zeitschrift f�r anorganische und allgemeine Chemie 623, no. 12 (1997): 1903–11. http://dx.doi.org/10.1002/zaac.19976231214.

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Sundararaju, Kavya, Ramesh Kumar Chidambaram, and Radhakrishnan Narayanaswamy. "SYNTHESIS, CHARACTERIZATION, AND MOLECULAR DOCKING ANALYSIS OF PROLINE (PYRROLIDINE 2-CARBOXYLIC ACID) AND PROLINAMIDE (PYRROLIDINE 2-CARBOXYLIC ACID AMIDE) ISOMERS AS BACTERIAL COLLAGENASE INHIBITORS." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 487. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.29894.

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Objectives: D-proline is an isomer of L-proline, naturally occurring amino acid. Apart from this, several proline homologs and analogs are available in nature. For instance, hydroxyproline one of proline analog plays a key role in collagen function. Inhibition of collagenase activity plays a significant role in protecting the unbalanced turnover of collagen, caused due to inflammation and photoaging of skin. This prompted us to carry out the study on proline and prolinamide isomers.Methods: These proline and prolinamide isomers were evaluated on the docking behavior of bacterial collagenase us
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Sundararaju, Kavya, Ramesh Kumar Chidambaram, and Radhakrishnan Narayanaswamy. "SYNTHESIS, CHARACTERIZATION, AND MOLECULAR DOCKING ANALYSIS OF PROLINE (PYRROLIDINE 2-CARBOXYLIC ACID) AND PROLINAMIDE (PYRROLIDINE 2-CARBOXYLIC ACID AMIDE) ISOMERS AS BACTERIAL COLLAGENASE INHIBITORS." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 487. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.29894.

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Objectives: D-proline is an isomer of L-proline, naturally occurring amino acid. Apart from this, several proline homologs and analogs are available in nature. For instance, hydroxyproline one of proline analog plays a key role in collagen function. Inhibition of collagenase activity plays a significant role in protecting the unbalanced turnover of collagen, caused due to inflammation and photoaging of skin. This prompted us to carry out the study on proline and prolinamide isomers.Methods: These proline and prolinamide isomers were evaluated on the docking behavior of bacterial collagenase us
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Du, Ganhong, Jun Ling, Fangyu Hu, Keyuan Liu, Long Ye, and Liming Jiang. "Bioinspired Polymer-Bound Organocatalysts for Direct Asymmetric Aldol Reaction: Experimental and Computational Studies." Catalysts 9, no. 5 (2019): 398. http://dx.doi.org/10.3390/catal9050398.

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A series of poly(2-oxazoline) (POX) derivatives bearing prolinamide pendants were designed as organocatalysts and evaluated in the direct asymmetric aldol reaction between aromatic aldehydes and cyclic ketones. The structural variation of the alkyl spacer connecting the polymer backbone with the catalytic unit was applied so as to deduce structure–performance relationships combined with comparable experiments from model catalysts. Results showed that the POX-bound prolinamides can promote the aldol reaction more effectively as compared to their small-molecular and non-POX-bound analogs. The ca
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Mousa, Mai H. A., Nermin S. Ahmed, Kai Schwedtmann, et al. "Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors." Pharmaceuticals 14, no. 4 (2021): 292. http://dx.doi.org/10.3390/ph14040292.

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Hepatitis C virus (HCV) is an international challenge. Since the discovery of NS5A direct-acting antivirals, researchers turned their attention to pursue novel NS5A inhibitors with optimized design and structure. Herein we explore highly potent hepatitis C virus (HCV) NS5A inhibitors; the novel analogs share a common symmetrical prolinamide 2,7-diaminofluorene scaffold. Modification of the 2,7-diaminofluorene backbone included the use of (S)-prolinamide or its isostere (S,R)-piperidine-3-caboxamide, both bearing different amino acid residues with terminal carbamate groups. Compound 26 exhibite
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Arivalagan, Premkumar Rathinam, and Yan Zhao. "Interfacial catalysis of aldol reactions by prolinamide surfactants in reverse micelles." Organic & Biomolecular Chemistry 13, no. 3 (2015): 770–75. http://dx.doi.org/10.1039/c4ob02074j.

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Yadav, Geeta Devi, and Surendra Singh. "(l)-Prolinamide imidazolium hexafluorophosphate ionic liquid as an efficient reusable organocatalyst for direct asymmetric aldol reaction in solvent-free condition." RSC Advances 6, no. 102 (2016): 100459–66. http://dx.doi.org/10.1039/c6ra23652a.

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Chauhan, Ajay, Sushovan Paladhi, Manish Debnath, and Jyotirmayee Dash. "Selective recognition of c-MYC G-quadruplex DNA using prolinamide derivatives." Organic & Biomolecular Chemistry 14, no. 24 (2016): 5761–67. http://dx.doi.org/10.1039/c6ob00177g.

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Kucherenko, A. S., A. A. Kostenko, V. V. Gerasimchuk, and S. G. Zlotin. "Stereospecific diaza-Cope rearrangement as an efficient tool for the synthesis of DPEDA pyridine analogs and related C2-symmetric organocatalysts." Organic & Biomolecular Chemistry 15, no. 33 (2017): 7028–33. http://dx.doi.org/10.1039/c7ob01852e.

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Dissertations / Theses on the topic "Prolinamid"

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Viózquez, Cámara Santiago Fidel. "BINAM-prolinamidas como organocatalizadores en síntesis asimétrica." Doctoral thesis, Universidad de Alicante, 2010. http://hdl.handle.net/10045/17371.

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En la presente memoria se describe la síntesis y aplicación de varios organocatalizadores quirales en reacciones aldólicas y adición Michael. Para ello se describe la síntesis de distintos compuestos derivados de 1,1'- Binaftil-2,2'-diamina (Binam) y prolina. Dichos compuestos se aplican en la reacción aldólica intermolecular sin disolvente empleando aldehídos como electrófilos. En estas condiciones se llega a obtener excesos enantioméricos de hasta el 98%. Además, se estudia la recuperación del catalizador del medio de reacción. También se detalla el estudio llevado a cabo sobre el mecanismo
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Monge, Marcet Amalia. "Silices hybrides dérivées de prolinamide et des sels d’imidazoliums : applications en catalyse." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2011. http://www.theses.fr/2011ENCM0007.

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La récupération et le recyclage des systèmes catalytiques dans la formation de liaisons carbone-carbone reste un défi scientifique important pour des raisons économiques et environnementales. Leur immobilisation sur des polymères insolubles permet une séparation simple par filtration et une purification facile des composés finaux. Les organosilices sont des gels de silice modifiés par des fragments organiques. Elles ont été appliquées comme supports pour une grande variété de catalyseurs. Dans ce travail, différentes organosilices ont été préparées par le procédé sol-gel ou par des méthodes de
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Navarro, Moles Fernando Javier. "Reacciones aldólicas enantioselectivas con α-oxoaldehídos organocatalizadas por prolinamidas derivadas de Binam". Doctoral thesis, Universidad de Alicante, 2014. http://hdl.handle.net/10045/39870.

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En el año 2003, nuestro grupo de investigación comenzó a trabajar en el campo de la organocatálisis haciendo uso de prolinamidas como catalizadores. En el presente trabajo se muestra la síntesis y aplicación de varios organocatalizadores quirales derivados de 1,1'-binaftil-2,2'-diamina (Binam) y prolinamidas en la reacción aldólica directa de α-oxoaldehídos como aceptores tales como ácido glioxílico, glioxilato de etilo, metilglioxal y 2,2-dimetoxiacetaldehído, con varios tipos de cetonas y aldehídos como donores, con el fin de obtener derivados de γ-oxo-α hidroxicarboxílicos con un alto nivel
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Akkoca, Hasan Ufuk. "Synthesis Of Bifunctional 2-aminodmap/prolinamide Organocatalysts And Their Use In Asymmetric Michael Reaction To Afford Warfarin." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12613984/index.pdf.

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In the first part of this thesis, the construction of the novel bifunctional proline-(1R,2R)-2-aminoDMAP organocatalyst backbone is described. Target compound has both Lewis base and Br&oslash<br>nsted acid catalaphoric sites. The Lewis base site is synthesized via selective mono-N-pyridilization of trans-(1R,2R)-cyclohexane-1,2-diamine by Cu catalysis and Br&oslash<br>nsted acid site is subsequently introduced by anchoring L-proline unit. In the second part, catalytic activities of organocatalysts are tested in asymmetric Michael addition reaction between a cyclic 1,3-dicarbonyl compound 4-hy
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Mitsui, Kazuhiko. "Dendritic Effects in Homogeneous Asymmetric Catalysis." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1245200227.

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Chassillan, Louis. "New Chiral Bifunctional Organocatalysts : Synthesis and Application in Enantioselective Reactions Under Batch and Continuous-Flow Conditions." Thesis, université Paris-Saclay, 2022. http://www.theses.fr/2022UPASF027.

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Au cours des dernières années, l’organocatalyse asymétrique a connu un engouement sans précédent et de nombreux catalyseurs organiques ont été synthétisés dans le but d’effectuer des réactions plus rapides et plus sélectives. Cependant, étant donné la demande croissante de molécules chirales dans l’industrie, il demeure crucial de développer de nouveaux outils afin de rendre leur production plus efficace. Pour ce faire, l’utilisation de la catalyse bifonctionnelle apparait comme une évidence du fait de sa capacité à activer simultanément le nucléophile et l’électrophile et ainsi permettre un m
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Prause, Felix [Verfasser], and Matthias [Akademischer Betreuer] Breuning. "5-Cis-substituierte Prolinamine : Modulare Synthese und Anwendung in der enantioselektiven Katalyse / Felix Prause ; Betreuer: Matthias Breuning." Bayreuth : Universität Bayreuth, 2017. http://d-nb.info/1136659137/34.

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Guevara, Hornedo Mar��a del Pilar. "Dise��o y s��ntesis de una nueva prolinamida quiral y su aplicaci��n como organocatalizador en la reacci��n ald��lica." Thesis, Universidad de las Am��ricas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/lqu/guevara_h_md/.

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El presente proyecto de tesis desarrolla un nuevo organocatalizador del tipo prolinamida, adem��s posee simetr��a C2, este factor hipot��ticamente aumenta la enantioselectividad de los organocatalizadores. Se prob�� su poder organocatal��tico en la reacci��n ald��lica modelo, la condensaci��n de 4-nitrobenzaldeh��do con acetona, obteni��ndose diversos resultados (Ver Cap��tulo 5 RESULTADOS Y DISCUSI��N). Entre las condiciones que destacan son el uso del organocatalizador (1) dise��ado y sintetizado en este proyecto en una concentraci��n al 10 mol%, 1 equivalente de 4- nitrobenzaldeh��do, 5 equ
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Gut, Bartosz. "Synteza aldoz na drodze enancjoselektywnej reakcji aldolowej." Praca doktorska, 2015. https://ruj.uj.edu.pl/xmlui/handle/item/45007.

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Hita, López María del Carmen. "BINAM-prolinamidas: nuevos organocatalizadores quirales en reacciones aldólicas." Doctoral thesis, 2007. http://hdl.handle.net/10045/14373.

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En la presente memoria se describe la síntesis y aplicaciones de nuevos organocatalizadores derivados de B1NAM y prolina en reacciones aldólicas. Se ha puesto a punto la síntesis de las diferentes prolinamidas derivadas de BINAM y prolina, discutiendo su estructura, relación entre ellas, así como su recuperación. Se ha estudiado la actividad catalítica de los nuevos catalizadores BINAM-prolinamidas en condensación aldólica directa entre aldehidos y cetonas alifáticas, en diferentes disolventes comparando con L-Pro. Las prolinamidas han sido recuperadas por técnicas de extracción sencillas, pud
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Book chapters on the topic "Prolinamid"

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Itsuno, S., and N. Haraguchi. "Supported Prolinamide Catalysts." In Brønsted Base and Acid Catalysts, and Additional Topics. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00513.

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Conference papers on the topic "Prolinamid"

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Ahmed, Nermin, Mai Mousa, Kai Schwedtmann, et al. "Design and synthesis of novel symmetric diaminofluorene prolinamide analogues as potent hepatitis C virus inhibitors." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07367.

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