Relevant bibliographies by topics / Proline – Analogues

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Proline – Analogues'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Proline – Analogues"

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Mauger, Anthony B. "Naturally Occurring Proline Analogues." Journal of Natural Products 59, no. 12 (1996): 1205–11. http://dx.doi.org/10.1021/np9603479.

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Tolmachova, Nataliya A., Ivan S. Kondratov, Violetta G. Dolovanyuk та ін. "Synthesis of new fluorinated proline analogues from polyfluoroalkyl β-ketoacetals and ethyl isocyanoacetate". Chemical Communications 54, № 69 (2018): 9683–86. http://dx.doi.org/10.1039/c8cc05912h.

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Díez, David, Ana B. Antón, Javier Peña, et al. "New proline analogues for organocatalysis." Tetrahedron: Asymmetry 21, no. 7 (2010): 786–93. http://dx.doi.org/10.1016/j.tetasy.2010.05.005.

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Tritsch, Denis, Hiba Mawlawi, and Jean-François Biellmann. "Mechanism-based inhibition of proline dehydrogenase by proline analogues." Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1202, no. 1 (1993): 77–81. http://dx.doi.org/10.1016/0167-4838(93)90065-y.

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Randall, K., M. Lever, B. A. Peddie, and S. T. Chambers. "Accumulation of natural and synthetic betaines by a mammalian renal cell line." Biochemistry and Cell Biology 74, no. 2 (1996): 283–87. http://dx.doi.org/10.1139/o96-030.

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Intracellular accumulation of different betaines was compared in osmotically stressed Madin Darby canine kidney (MDCK) cells to model the betaine accumulation specificity of the mammalian inner medulla and to show how this accumulation differed from that of bacteria. All betaines accumulated less than glycine betaine. Arsenobetaine (the arsenic analogue of glycine betaine) accumulated to 12% of the glycine betaine levels and the sulphur analogue dimethylthetin accumulated to >80%. Most substituted glycine betaine analogues accumulated to 2–5% of intracellular glycine betaine concentrations,
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Calaza, M. Isabel, and Carlos Cativiela. "Stereoselective Synthesis of Quaternary Proline Analogues." European Journal of Organic Chemistry 2008, no. 20 (2008): 3427–48. http://dx.doi.org/10.1002/ejoc.200800225.

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Galardy, R. E., and Z. P. Kortylewicz. "Inhibitors of angiotensin-converting enzyme containing a tetrahedral arsenic atom." Biochemical Journal 226, no. 2 (1985): 447–54. http://dx.doi.org/10.1042/bj2260447.

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A series of tetrahedral oxo acids of Group VA and VIA elements and of silicon and boron were examined as inhibitors of angiotensin-converting enzyme. Arsenate is a competitive inhibitor with a Ki of 27 +/- 1 mM, at least 10-fold more potent than phosphate. Dimethylarsinate is a competitive inhibitor with a Ki of 70 +/- 9 mM, 2-fold more potent than dimethylphosphinate. Oxo acids of boron, silicon, antimony, sulphur and selenium are not inhibitors. On the basis of these results and the strong inhibition of this zinc metallopeptidase by substrate analogues containing a tetrahedral phosphorus ato
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Calaza, M. Isabel, Francisco J. Sayago, Pedro Laborda, and Carlos Cativiela. "Synthesis of [c]-Fused Bicyclic Proline Analogues." European Journal of Organic Chemistry 2015, no. 8 (2015): 1633–58. http://dx.doi.org/10.1002/ejoc.201403121.

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Diez, David, Ana B. Anton, Javier Pena, et al. "ChemInform Abstract: New Proline Analogues for Organocatalysis." ChemInform 41, no. 47 (2010): no. http://dx.doi.org/10.1002/chin.201047026.

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Flores-Ortega, Alejandra, Ana I. Jiménez, Carlos Cativiela, Ruth Nussinov, Carlos Alemán та Jordi Casanovas. "Conformational Preferences of α-Substituted Proline Analogues". Journal of Organic Chemistry 73, № 9 (2008): 3418–27. http://dx.doi.org/10.1021/jo702710x.

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Dissertations / Theses on the topic "Proline – Analogues"

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Athlan, Audrey. "Synthèse d'un dérivé de l'acide pipérazique comme analogue rigide de la proline : étude de son influence sur la formation de coudes peptidiques." Lyon 1, 2000. http://www.theses.fr/2000LYO10278.

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Les coudes peptidiques (ou peptide turns) constituent des sites où la direction de la chaîne polypeptidique s'inverse. Localisés à la surface des protéines, les turns sont impliqués dans de nombreux phénomènes de reconnaissance comme les interactions ligand-recepteur, antigène-anticorps, ADN-protéine, etc. La proline, un acide aminé souvent présent au niveau de ces coudes peptidiques, semble favoriser la formation des turns, mais la présence de la proline à elle seule n'est pas suffisante pour induire un coude. De nombreuses stabilisations comme les liaisons hydrogène, ponts disulfure sont néc
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Flores, Ortega Alejandra. "Conformational properties of constrained proline analogues and their application in nanobiology." Doctoral thesis, Universitat Politècnica de Catalunya, 2009. http://hdl.handle.net/10803/6477.

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This thesis is composed of two parts:<br/><br/>We have used different computer simulation techniques to investigate the impact of different chemical modifications on the conformational preferences of proline and to examine the application of conformationally constrained proline analogues in Nanobiology.<br/><br/>Specifically, the first part shows the conformational study of proline derivatives that were obtained by introducing one or more double bonds in the pyrrolidine ring, by replacing the &#945;-hydrogen atom by an alkyl group or by incorporating a polar substituent at the &#946;- or &#947
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Aubry, Carine. "Synthèse, analyse structurale et activité biologique d'analogues rigides d'un antagoniste de l'octadécaneuropeptide ODN." Rouen, 2003. http://www.theses.fr/2003ROUES002.

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L'ODN fait partie d'une série de peptides, les endozépines, qui se lient aux récepteurs des benzodiazépines mais aussi à un récepteur métabotropique astrocytaire en cours de caractérisation. Des études de relations structure-activité menées sur des analogues de l'ODN ont montré que l'octapeptide Ct de l'ODN a une activité égale à celle de l'ODN. Parallèlement, le premier antagoniste complet du récepteur métabotropique a été synthétisé. Il correspond à l'OP cyclisé et modifié en position 5 par une D-leucine. La conformation de ce dernier, déterminée par RMN, a permis de montrer l'existence de d
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Clavaud, Cécile. "Développement de ligands de protéines par assemblage combinatoire autour d'un coeur de rheniumV : application à la cyclophiline hCyp-18." Paris 11, 2006. http://www.theses.fr/2006PA112006.

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Cette thèse décrit une nouvelle stratégie pour le développement de composés organométalliques bioactifs, reposant sur l'assemblage combinatoire de sous-chimiothèques (A et B) indépendantes mais complémentaires et capables de coordiner un cœur métallique M, pour former des complexes A-M-B ligands potentiels de biomolécules. La coordination des métaux, bien adaptée à la production de diversité moléculaire est couramment utilisée en chimie médicinale, en médecine nucléaire diagnostique et thérapeutique. Parmi les éléments utilisables, le rhénium et le technétium sont des métaux de choix pour le d
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Hu, Zilun. "CONSTRAINED β–PROLINES: I. METHANOPYRROLIDINE β-AMINO ACIDS: SYNTHESIS AND CHARACTERIZATION OF NOVEL C6- SUBSTITUTED ANALOGUES AND PEPTIDE OLIGOMERS II. SYNTHESIS OF 2,2-DISUBSTITUTED PYRROLIDINE-3-CARBOXYLIC ACIDS". Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/339315.

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Chemistry<br>Ph.D.<br>In the study of structurally restricted cyclic β-amino acids and peptides, methanopyrrolidine-5-carboxylic acids (MetPyr-5-acids), or 5-syn-carboxy-2-azabicyclo[2.1.1] hexanes, and derivatives were investigated. MetPyr-5-acids are a series of highly conformationally constrained β-proline derivatives, which belong to a novel category of β-amino acids utilized as building blocks for the synthesis of β-peptides. These β-peptides lack the backbone hydrogen bonds necessary for folding in the usual manner. Substituents and functional groups in this ring system were envisioned t
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Gadamsetty, Surendra Babu. "Application of sulfonimidoyl substituted allyltitanium (IV) complexes to the asymmetric synthesis of alkenyloxiranes, 2,3-dihydrofurans, tetrahydrofurans, unsaturated proline analogues and allylic alcohols." [S.l.] : [s.n.], 2007. http://deposit.ddb.de/cgi-bin/dokserv?idn=983701350.

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Garcia, Ariel Lazaro Llanes. "Reação de arilação de Heck com sais de arenodiazonio : aplicações nas sinteses totais de prolinas e pirrolidinas poliidroxiladas, rolipram e analogos do baclofeno, e na sintese formal de prepolicitrina A e policitrina A." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/248358.

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Orientador: Carlos Roque Duarte Correia<br>Acompanha Anexo denominado V.2. Paginação continua<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-12T12:04:47Z (GMT). No. of bitstreams: 1 Garcia_ArielLazaroLlanes_D.pdf: 15520800 bytes, checksum: 2744757a92f3045d187a1c68320729d5 (MD5) Previous issue date: 2008<br>Resumo: A reação de arilação de Heck-Matsuda é um procedimento sintético valioso e extremamente versátil para a formação de ligações carbono-carbono, baseada no acoplamento de uma olefina com um sal de arenodiazônio na p
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Smet-Nocca, Caroline. "Etude des interactions entre la peptidyl-prolyl cis/trans isomérase Pin1 et la protéine microtubulaire Tau. Recherche d'inhibiteurs ciblant la liaison de Pin1 à ses substrats phosphorylés." Phd thesis, Université du Droit et de la Santé - Lille II, 2004. http://tel.archives-ouvertes.fr/tel-00354986.

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La phosphorylation constitue un mécanisme de régulation de la fonction biologique des protéines lié au contrôle des associations inter-moléculaires, de l'activité enzymatique ou de la liaison de ligands. L'isomérisation des liaisons Ser/Thr-Pro après phosphorylation par des kinases spécifiques, souvent impliquées dans le contrôle du cycle cellulaire, se présente comme un nouveau mode de régulation. Ces deux mécanismes de signalisation sont étroitement liés par l'intermédiaire d'enzymes catalysant l'isomérisation cis/trans des prolines au niveau de motifs Ser/Thr-Pro phosphorylés telles que les
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Manfre, Franco. "Synthese de substrats suicide potentiels de la proline deshydrogenase et des beta-lactamases." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13157.

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Lima, Mary Anne Sousa. "Enecarbamatos endociclicos enantiomericamente puros em sintese organica assimetrica : estudos visando a sintese enantiosseletiva de analogos da (-)-detoxinina e de aminoacidos derivados da 4-hidroxi-prolina benzilados em C5." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249867.

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Orientador : Carlos Roque Duarte Correia<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-07-27T23:15:06Z (GMT). No. of bitstreams: 1 Lima_MaryAnneSousa_D.pdf: 5888662 bytes, checksum: 3f44af19017e11ad7ebf30b59bcefd1d (MD5) Previous issue date: 1999<br>Doutorado
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Book chapters on the topic "Proline – Analogues"

1

Stavropoulos, G., K. Karagiannis, and D. Papaioannou. "Synthesis of TRH analogues incorporating cis- and trans-4-hydroxy-L-proline." In Peptides 1990. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3034-9_77.

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Armishaw, Christopher J., Anders A. Jensen, Christian Skonberg, Tommy Liljefors, and Kristian Strømgaard. "Synthesis and Biological Activity of Novel α-Conotoxin Analogues Incorporating Substituted Proline Derivatives." In Advances in Experimental Medicine and Biology. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-73657-0_82.

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Kendrick, David A., Hamish Ryder, Graeme Semple, Andrew Sheppard, and Michael Szelke. "The synthesis of α-(3-indolylmethyl) proline-containing compounds as CCK ligands: Analogues of PD-134308." In Peptides 1992. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1470-7_261.

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Bailey, P. D., K. M. Morgan, D. J. Londesbrough, and R. D. Wilson. "Synthesis of pipecolic acid derivatives via the Diels-Alder reaction and their potential as proline analogues." In Peptides. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_51.

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Sobolewski, Dariusz, Adam Prahl, Jiřina Slaninová, and Bernard Lammek. "Analogues of arginine vasopressin modified at position 2 with proline derivatives: selective antagonists of oxytocin in vitro." In Advances in Experimental Medicine and Biology. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-73657-0_218.

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Galoyan, Armen A. "Prophylaxis and Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection with Proline-Rich Polypeptides Galarmin and Its Structural Analogues in an Experimental Murine Model." In Advances in Neurobiology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-3667-6_6.

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Poiani, George J., James M. Sumka, Carol A. Tozzi, Wei-Chi Liao, and David J. Riley. "Local delivery of liposome-encapsulated proline analogue prevents pulmonary hypertension in the rat." In Amino Acids. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-011-2262-7_74.

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Armstrong, Alan, and Paul Dingwall. "Mechanistic Understanding of Proline Analogs and Related Protic Lewis Bases (n?→?π* )." In Lewis Base Catalysis in Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527675142.ch6.

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Baláspiri, Lajos, Csaba Somlai, Gyula Telegdy, and Ferenc A. László. "Synthesis and biological studies of some arginine-vasopressin analogs containing unusual, mainly proline-like amino acids." In Peptides 1990. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3034-9_274.

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Cai, Chaozhong, Wei Wang, Chiyi Xiong, Vadim A. Soloshonok, Minying Cai, and Victor J. Hruby. "Synthesis of β and γ-Substituted Prolines for Conformation-Activity Relationship Studies of the α-MSH Analogue MT-II." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_4.

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